Publications by authors named "Roya Mansour-Ghanaei"

11 Publications

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Investigating the relationship between social support and quality of life in the elderly.

J Educ Health Promot 2020 31;9:215. Epub 2020 Aug 31.

Department of Social Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Background: Dynamic aging depends on providing opportunities to improve the quality of life of the elderly. The objective of this study was to investigate the relationship between social support and quality of life in the elderly in Guilan.

Materials And Methods: This descriptive-correlational study was conducted in the elderly who visited urban public places in the East of Guilan (mosques, parks, weekly markets, and clubs). A total of 168 elderly who met the inclusion criteria were selected through two-stage, cluster, and convenience sampling. Data were collected using Phillips Standard 23-item social support scale and 12-item quality of life scale-short form. Data were analyzed through descriptive and inferential statistics (Pearson correlation coefficient).

Results: The mean score of social support in the elderly in Guilan was 73.25 ± 9.18 and the mean quality of life was obtained at 24.67 ± 7.06. Data analysis showed that there was a significant and positive correlation between social support and quality of life (r = 0.29, < 0.0001).

Conclusions: Increased social support leads to a higher quality of life in the elderly. Thus, it is necessary to timely identify the needs and promote comprehensive social support to improve the quality of life in the elderly.
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http://dx.doi.org/10.4103/jehp.jehp_149_20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530409PMC
August 2020

Knowledge About Gastrointestinal Cancers in People Referred for Endoscopy and Colonoscopy During a Screening Program: a Cross-sectional Study in Guilan, North of Iran.

J Gastrointest Cancer 2021 Mar;52(1):192-200

Caspian Digestive Disease Research Center, Guilan University of Medical Sciences, Rasht, Iran.

Purpose: The most northern and northwestern regions of Iran are at a high risk for gastrointestinal cancers. In this study, we evaluated knowledge of gastrointestinal (GI) cancers in people referred for endoscopy and colonoscopy screening.

Methods: This cross-sectional study was carried out among 461 people who were under the patronage of a local relief foundation and referred for endoscopy and colonoscopy to the Gastrointestinal and Liver Disease Research Center (GLDRC), Rasht, north of Iran, from March 2016 to March 2017. A well-defined two-sectioned questionnaire was carried out for each group.

Results: Overall, 300 and 161 individuals were in the gastric and colon cancer knowledge group, respectively. The level of knowledge in various areas of gastric and colon cancer was desirable. In general, the average of different domains in gastric and colon cancer knowledge questions were 20.2 ± 6.6 and 19.2 ± 4.9, with the knowledge level higher than the mean in gastric cancer (58%) and colon cancer (67.1%). The mean score of knowledge of GI cancers in terms of risk factor indicated a significant relationship between BMI and alcohol consumption. Meanwhile, a meaningful relationship between symptoms and BMI with knowledge was declared. About domains of colon cancer, there was a significant relationship between younger age and knowledge in the risk factor.

Conclusions: The results of this study can provide an opportunity to formulate strategies to achieve goals, especially in the field of education, prevention, and control of the disease by raising knowledge for the general public and educating people who are responsible for providing and delivering health services to this community.
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http://dx.doi.org/10.1007/s12029-020-00383-2DOI Listing
March 2021

The Lifestyle Characteristics in Non-Alcoholic Fatty Liver Disease in the PERSIAN Guilan Cohort Study.

Open Access Maced J Med Sci 2019 Oct 14;7(19):3313-3318. Epub 2019 Sep 14.

Gastrointestinal & Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.

Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is the most common cause of chronic liver disease worldwide. Since the effect and safety of pharmacotherapy for NAFLD are unknown, the proper management of lifestyle is crucial.

Aim: The present study was conducted to determine the status of food, Physical Activity (PA), and sleep in patients with and without NAFLD.

Methods: In this analytical- cross-sectional study, 630 clients with 36-60 years old who referred to the PERSIAN Guilan cohort study were included through simple non-random sampling. The developed questionnaire and lifestyle characteristics, including the status of nutrition, physical activity, and sleep, were completed for all samples. BMI was also calculated by determining weight and height, and fatty liver was confirmed based on abdominal ultrasound.

Results: The prevalence of NAFLD in this study was by 43.7% (275 / 630). Smoking, alcohol consumption, BMI, and weight loss over the past six months, regular exercise and exercise intensity, sedentary living, speed of eating, consuming fatty food, red meat, sweets beverages, and use of saturated fatty acid (SFA), and consuming fruits and vegetables were associated with presence of NAFLD (all p < 0.05). However, no significant relationship was observed between the parameters of sleep duration, the interval between dinner and night sleep, consuming breakfast and snack during the day and NAFLD (All p > 0.05).

Conclusion: The onset and progression of NAFLD are associated with lifestyle. Therefore, dietary therapy solutions, physical activity, and sleep and rest situations should be paid attention for people with or at risk of NAFLD.
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http://dx.doi.org/10.3889/oamjms.2019.647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953935PMC
October 2019

A correlational study of hope and its relationship with spiritual health on hemodialysis patients.

J Educ Health Promot 2019 29;8:146. Epub 2019 Jul 29.

Department of Social Medicine, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Background: One of the main psychological problems in hemodialysis patients is hopelessness. Spiritual health leads the patients toward hope and goal in life. Given the importance of the issue and the little research in this area, this study aimed to assess hope and its relationship with spiritual health on hemodialysis patients in Rasht Razi Hospital of Iran.

Materials And Methods: This correlational study carried out on 103 patients who admitted in Rasht Razi Hospital Hemodialysis Center by simple random sampling. The data were collected through Snyder's Hope Scale and Spiritual Health. The psychomotricity of these questionnaires has been confirmed in domestic studies. The data were analyzed by using descriptive and inferential statistics (Pearson correlation coefficient).

Results: The majority of the patients were male (59.2%), in the age group of above 60 (46.60%), married (83.5%), with low income (60.2%), and under diploma (53.4%). The mean of hope score was 36.36 (±9.10) that showed the high level of hope in the majority of the patients. The mean of the total spiritual health score was 227.93 (±19.01) that indicates the high level of spiritual health in hemodialysis patients. There was a positive and significant correlation between spiritual health and its dimensions and hope ( < 0.05).

Conclusions: The results of this study approve the importance of spiritual health as an effective variable on hope among hemodialysis patients. Hence, health-care providers and clinical experts are recommended to focus on spiritual health to increase hope among such patients.
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http://dx.doi.org/10.4103/jehp.jehp_461_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691628PMC
July 2019

Prevalence of pre-cancerous colon lesions in referred patients under patronage of a local relief foundation in Guilan province.

J Med Life 2019 Apr-Jun;12(2):133-139

Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.

Colon cancer is the most commonly diagnosed gastrointestinal cancers in developed countries with varied incidence and the onset age of disease worldwide. Overall, 161 participants who were under patronage of a local relief foundation and referred to the endoscopy ward of Razi Hospital affiliated to the Guilan University of Medical Sciences. These patients have been aged more than 50 or more than 40 years with history of colorectal cancer in their first-degree family were enrolled from March 2016-March 2017. Demographic information were collected. Colonoscopy was performed and histopathological evaluation of observed lesions and polyps was done. Most of participants were female (113 individuals, 70.2%) and aged 50-60 years (83 individuals, 51.6%). Seventy-four (46%) had certain lesions. Most of colonoscopy findings were observed in the ascending colon in which depressed polyps and diverticulum were most frequent. However, rectum showed the most histological findings. All polyps of descending and ascending colons were neoplastic, while most of rectal polyps were non-neoplastic. Male patients, who were aged more than 60 years and smokers had significant higher percentage of both lesions and polyps in their colon (p<0.05). Moreover, significant positive association was detected between exposure to harmful industries and having polyps (p=0.01). We found male gender, higher age, smoking, and exposure to harmful industries as important risk factors for having colorectal lesions, which must be confirmed in further studies.
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http://dx.doi.org/10.25122/jml-2018-0074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685299PMC
October 2019

Gastrointestinal symptoms in patients with diabetes mellitus and non-diabetic: A cross-sectional study in north of Iran.

Diabetes Metab Syndr 2019 May - Jun;13(3):2236-2240. Epub 2019 May 25.

GI Cancer Screening and Prevention Research Center, Guilan University of Medical Sciences, Rasht, Iran; Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran. Electronic address:

Background And Aim: Gastrointestinal (GI) symptoms are common in patients with diabetes mellitus (DM), which involved in high cost of health care and low quality of life. The aim of this study to investigate the prevalence of GI symptoms in diabetic patients referred to the Gastrointestinal and Liver Diseases Research Center (GLDRC), Guilan University of Medical Sciences (Rasht, Iran) using a validated questionnaire.

Methods: In this descriptive, cross-sectional study, 255 diabetic patients and 255 non-diabetic subjects were recruited. Participants were randomly selected. The questionnaire recorded GI symptoms among the study population.

Results: GI symptoms were reported in 91.4% of diabetic patients, and 42.1% of them were male. The common GI symptoms in diabetic patients were flatulence (33.0%), followed by retrosternal pain (14.9%), belching (13.7%), postprandial fullness (12.5%), and constipation (11.4%). Retrosternal pain, constipation, flatulence, loss of appetite, and abdominal distention were more prevalent in diabetic women than men.

Conclusions: DM is associated with high prevalence rate of upper and lower GI symptoms. This effect may be linked to gender and poor glycemic control in diabetic patients, but not to type and duration of diabetes.
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http://dx.doi.org/10.1016/j.dsx.2019.05.028DOI Listing
December 2019

Biochemical markers and lipid profile in nonalcoholic fatty liver disease patients in the PERSIAN Guilan cohort study (PGCS), Iran.

J Family Med Prim Care 2019 Mar;8(3):923-928

Department of Gastroenterology, Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.

Background And Aim: Nonalcoholic fatty liver disease (NAFLD) is a global epidemic that is often asymptomatic and silent, and progresses slowly. This study aimed to determine the biochemical markers and lipid profile among NAFLD patients and their possible relationship with degrees of fatty liver.

Methods: This is analytical cross-sectional study, in which, 950 individuals referred to the PERSIAN Guilan cohort study were included through sequential sampling method. The demographic information and blood pressure of the subjects were taken and the blood sample was prepared to investigate the biochemical markers and lipid profile. Also, abdominal ultrasonography was performed to investigate NAFLD and its grades. For data analysis, independent sample -test, one-way ANOVA, and logistic regression model were used, where < 0.05 was considered significant.

Results: The systolic blood pressure (SBP) ( < 0.001), diastolic blood pressure (DBP) ( < 0.001), hepatic enzymes (aspartate aminotransferase [AST], < 0.001, alanine aminotransferase [ALT], < 0.001; gamma-glutamyle transferase [GGT], < 0.001; AST/ALT ratio, < 0.001), lipid profile (triglyceride [TG], < 0.001; total cholesterol [TC], = 0.008; high density lipoprotein [HDL], < 0.001; LDL-C/HDL-C (ratio), = 0.003; TC/HDL-C (ratio), < 0.001); and fasting blood sugar [FBS], < 0.001 correlated with NAFLD. However, there was no relationship between age ( = 0.34), alkaline phosphatase [ALP] ( = 0.26) and low-density lipoprotein [LDL] ( = 0.72). Further, a significant relationship was observed between AST ( < 0.001), ALT ( < 0.001), and GGT ( = 0.004) and NAFLD degrees based on the ultrasonography.

Conclusion: Biochemical markers and lipid profile are associated with NAFLD. Thus, it is recommended to investigate NAFLD in clinical settings in cases in which their changes are observed in patients through ultrasonography.
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http://dx.doi.org/10.4103/jfmpc.jfmpc_243_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482810PMC
March 2019

The role of anthropometric indices in the prediction of non-alcoholic fatty liver disease in the PERSIAN Guilan Cohort study (PGCS).

J Med Life 2018 Jul-Sep;11(3):194-202

Gastrointestinal & Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.

Non-alcoholic fatty liver disease (NAFLD) is an obesity-associated health problem that causes other liver diseases for the patient. Four anthropometric indices: body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) were analyzed as NAFLD predictors in the present study. From the total number of individuals who referred to the PERSIAN Guilan Cohort study (PGCS) located in the north of Iran during the period of study, a total of 960 people were enrolled in the present study. NAFLD was diagnosed using through an abdominal ultrasound exam. Height, weight, WC, BMI, WHR and WHtR were later calculated. Chi-square, ANOVA and logistic regression analyses were used to analyze the risk factors. Out of the 960 individuals who were enrolled in the study, 597 (62.2%) were male and 363 (37.8%) were female (with an average age of 47.21 ± 7.29 years). There was a significant relationship between weight and NAFLD (P<0.001). There was also a significant relationship between BMI (OR= 8.41; 95% CI = 5.59-12.75), WC (OR= 2.67; 95% CI = 2.05-3.48), WHR (OR= 3.84; 95% CI = 2.26-6.52), WHtR (OR= 28.53; 95% CI = 6.94-117.31) and NAFLD (P<0.001). The results of the logistic regression analysis showed that WHtR, BMI and WC were effective predictors for the risk of NAFLD while WHtR played a more important role in the prediction of NAFLD. Anthropometric indices, especially WHtR, as a simple screening tool, seem to be an important criterion for the detection of NAFLD.
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http://dx.doi.org/10.25122/jml-2018-0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197514PMC
December 2018

Association between knowledge, locus of control and health belief with self-management, Hb A1c level and number of attendances in type 1 diabetes mellitus patients.

Int J Clin Exp Med 2013 26;6(6):470-7. Epub 2013 Jun 26.

Gastrointestinal & Liver Diseases Research Center (GLDRC), Guilan University (Medical Sciences) Rasht, Iran.

This survey was designed to determine the association between knowledge, locus of control and health belief with self-management, Hb A1c level and Number of attendances in type 1 diabetic patients in Rasht, Guilan Province - North of Iran. Data was derived from chart reviews of 92 patients. Patients' glycosylated hemoglobin level and their number of health care attendances during the last 6 months were recorded. The four part questionnaires covered patients' demographic data, knowledge, perceived control and health belief of diabetes. A blood sample was taken from each patient. There was no significant relationship between demographic data such as gender, age, marital status, education, occupation, duration of the disease, place of living and family history with knowledge, health belief and locus of control (P > 0.05). Also the results didn't show any significant association between the complicated group and their knowledge and health belief (P > 0.05) while it was significantly related to their locus of control (P < 0.004). The majority of the samples had poor knowledge (59.8%), health belief (71.7%) and locus of control (62%). There was no significant relationship between patients' knowledge, health belief and locus of control with their glycosylated hemoglobin level, number of referrals and self-management. It is suggested by the present survey that locus of control, health belief and knowledge of patients are not found to have no practical effect upon diabetic self-management behavior or outcomes, according to the variables used and care for the diabetic patients must be tailored to individual requirements.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703118PMC
July 2013

Knowledge and attitude of medical science students toward hepatitis B and C infections.

Int J Clin Exp Med 2013 21;6(3):197-205. Epub 2013 Mar 21.

MS (Nursing), Faculty member, Gastrointestinal & Liver Diseases Research Center (GLDRC), Guilan University (Medical Sciences) Rasht, Iran.

The present survey aimed to determine the knowledge level and attitude of medical students in Guilan University toward Hepatitis B and C viruses' infections. In a cross-sectional survey, the knowledge and attitude of 424 medical science undergraduate students of nursing, midwifery, operating room technician, laboratory, anesthesiology and radiology in Guilan University of Medical Sciences toward Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections were investigated using a standardized questionnaire. The mean (SD) knowledge level of the medical students toward HBV and HCV were 17 ± 5 from 28 and 10.58 ± 6.7 from 29 questions respectively. Females, nursing students, forth year students, those who worked in hospital and those who had needle stick injuries (NSI) history showed significantly higher knowledge scores toward HBV (P< 0.05). Married students, anesthesiology students, those who were in their fourth year of study, and those who worked in hospital had significantly higher mean knowledge scores toward HCV (P< 0.05). Also students' attitude toward HBV and HCV was positively correlated with their mean knowledge level (r=0.14, p=0.004), (r=0.18, p=0.0001). Education on the nature, symptoms, transmission, prevention and treatment of HBV and HCV infections may increase the willingness of health care workers to care for infected persons.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609696PMC
April 2013

Frequency of celiac disease in patients with hypothyroidism.

J Thyroid Res 2012 28;2012:201538. Epub 2012 Mar 28.

Department of Endocrinology, Guilan University of Medical Sciences, Rasht, Iran.

Background. Celiac disease (CD) is closely associated with other autoimmune endocrine disorders, particularly autoimmune thyroid disease. The aim of this study was to find the frequency of celiac disease in patients with hypothyroidism in Guilan province, north of Iran. Methods. A total of 454 consecutive patients with hypothyroidism underwent celiac serological tests antiGliadin antibodies (AGA), antitissue transglutaminase antibodies (IgA-tTG) and antiendomysial antibodies (EMA-IgA). Small intestinal biopsy was performed when any of celiac serological tests was positive. Results. Eleven (2.4%) patients were positive for celiac serology, and two patients with documented villous atrophy were diagnosed with classic CD (0.4%; 95%). Two patients with classic CD had Hashimoto's thyroiditis (HT) (0.6%; 95%). Six (54.5%) of 11 were suffering from overt hypothyroidism and 45.5% from subclinical hypothyroidism. Six (54.5%) had HT, and 45.5% had nonautoimmune hypothyroidism. Conclusions. In this study, prevalence of CD was lower than other studies. Most of the patients with CD were suffering from HT, but there was no significant statistical relation between CD and HT.
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http://dx.doi.org/10.1155/2012/201538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321550PMC
August 2012