Roy Silverstein

Roy Silverstein

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CD36 and ERK5 link dyslipidemia to apoptotic-like platelet procoagulant function.

Curr Opin Hematol 2019 Sep;26(5):357-365

Blood Research Institute, Versiti Blood Center of Wisconsin.

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http://dx.doi.org/10.1097/MOH.0000000000000522DOI Listing
September 2019

Modification of HDL by reactive aldehydes alters select cardioprotective functions of HDL in macrophages.

FEBS J 2019 Aug 6. Epub 2019 Aug 6.

Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, USA.

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http://dx.doi.org/10.1111/febs.15034DOI Listing
August 2019

CD36 signaling in vascular redox stress.

Free Radic Biol Med 2019 May 27;136:159-171. Epub 2019 Feb 27.

Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, USA; Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2019.02.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488418PMC
May 2019

CD36 Enhances Vascular Smooth Muscle Cell Proliferation and Development of Neointimal Hyperplasia.

Arterioscler Thromb Vasc Biol 2019 Feb;39(2):263-275

From the Department of Biomedical Sciences, Marshall University Joan C. Edwards School of Medicine, Huntington, WV (H.Y., A.B., W.L.).

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.118.312186
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http://dx.doi.org/10.1161/ATVBAHA.118.312186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345504PMC
February 2019

Platelet metabolism meets thrombosis.

Blood 2018 09;132(11):1089-1091

Blood Center of Wisconsin.

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http://dx.doi.org/10.1182/blood-2018-08-865600DOI Listing
September 2018

Oxidized Lipid Uptake by Scavenger Receptor CD36 (Cluster of Differentiation 36) Modulates Endothelial Surface Properties and May Contribute to Atherogenesis.

Arterioscler Thromb Vasc Biol 2018 01;38(1):4-5

From the Department of Medicine, Medical College of Wisconsin, and Blood Research Institute, Blood Center of Wisconsin, Milwaukee.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.117.310351
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http://dx.doi.org/10.1161/ATVBAHA.117.310351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751929PMC
January 2018

Cardiotonic Steroids Stimulate Macrophage Inflammatory Responses Through a Pathway Involving CD36, TLR4, and Na/K-ATPase.

Arterioscler Thromb Vasc Biol 2017 08 15;37(8):1462-1469. Epub 2017 Jun 15.

From the Blood Research Institute, Blood Center of Wisconsin, Milwaukee (Y.C., W.H., M.Y., G.X., W.C., R.L.S.); Department of Cell Biology, Neurobiology and Anatomy (M.Y., R.L.S.) and Department of Medicine (R.L.S.), Medical College of Wisconsin, Milwaukee; and Departments of Medicine, Pharmacology and Surgery, Joan C. Edwards School of Medicine, Marshall University, Huntington, WV (Z.X.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532064PMC
August 2017

Linking Metabolic Dysfunction to Atherosclerosis Via Activation of Macrophage CD36 Gene Transcription by Retinol Binding Protein-4.

Circulation 2017 04;135(14):1355-1356

From Medical College of Wisconsin and Blood Center of Wisconsin, Milwaukee.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.027505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415385PMC
April 2017

Circulating protein Z concentration, PROZ variants, and unexplained cerebral infarction in young and middle-aged adults.

Thromb Haemost 2017 01 29;117(1):149-157. Epub 2016 Sep 29.

Dr. Jorge Kizer, Cardiovascular Clinical Research Unit, 1300 Morris Park Ave, Bronx, NY 10461, USA, Tel.: +1 718 430 2197, Fax: +1 718 839 7960, E-mail:

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http://dx.doi.org/10.1160/TH16-04-0277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798600PMC
January 2017

Metabolic Manipulation to Put the Brakes on Platelet Activation: A Potential Novel Pharmacologic Approach to Atherothrombosis.

Arterioscler Thromb Vasc Biol 2016 10;36(10):2031-2

From the Department of Medicine, Medical College of Wisconsin and Blood Research Institute of BloodCenter of Wisconsin, Milwaukee.

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http://dx.doi.org/10.1161/ATVBAHA.116.308218DOI Listing
October 2016

LPA/PKD-1-FoxO1 Signaling Axis Mediates Endothelial Cell CD36 Transcriptional Repression and Proangiogenic and Proarteriogenic Reprogramming.

Arterioscler Thromb Vasc Biol 2016 06 24;36(6):1197-208. Epub 2016 Mar 24.

From the Department of Medicine, Medical College of Wisconsin, Milwaukee (B.R., R.L.S.); Blood Research Institute, Blood Center of Wisconsin, Milwaukee (B.R., B.B., D.P.R., R.L.S.); Department of Neurological Surgery, Cardiovascular Research Center, Massachusetts General Hospital & Harvard Medical School, Boston (B.P.W.); and Department of Cancer Biology, Mayo Clinic, Jacksonville, FL (P.S.).

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http://dx.doi.org/10.1161/ATVBAHA.116.307421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882231PMC
June 2016

Acrolein impairs the cholesterol transport functions of high density lipoproteins.

PLoS One 2015 7;10(4):e0123138. Epub 2015 Apr 7.

Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123138PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388475PMC
April 2016

Extracellular Vesicles Activate a CD36-Dependent Signaling Pathway to Inhibit Microvascular Endothelial Cell Migration and Tube Formation.

Arterioscler Thromb Vasc Biol 2016 Mar 28;36(3):534-44. Epub 2016 Jan 28.

From the Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH (D.P.R.); Laboratory of Vascular Pathobiology, Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI (D.P.R., Y.C., R.L.S.); Department of Rheumatologic and Immunologic Disease, Orthopedic and Rheumatologic Institute, Cleveland Clinic Foundation, Cleveland, OH (R.A.H.-A.); and Department of Medicine, Medical College of Wisconsin, Milwaukee, WI (R.L.S.).

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http://dx.doi.org/10.1161/ATVBAHA.115.307085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767682PMC
March 2016

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.

Cell 2016 Mar 10;165(1):111-124. Epub 2016 Mar 10.

Department of Cellular & Molecular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA; Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862743PMC
March 2016

Atherothrombosis: Seeing Red?

Circulation 2015 Nov 14;132(20):1860-2. Epub 2015 Oct 14.

From Harrington Heart & Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH (D.I.S.); and Department of Medicine, Medical College of Wisconsin and Blood Research Institute, Blood Center of Wisconsin, Milwaukee (R.L.S.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.115.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651722PMC
November 2015

Oxidized LDL-bound CD36 recruits an Na⁺/K⁺-ATPase-Lyn complex in macrophages that promotes atherosclerosis.

Sci Signal 2015 Sep 8;8(393):ra91. Epub 2015 Sep 8.

Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI 53226, USA. Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

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http://dx.doi.org/10.1126/scisignal.aaa9623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852751PMC
September 2015

Ferric chloride-induced murine carotid arterial injury: A model of redox pathology.

Redox Biol 2013 26;1:50-5. Epub 2013 Jan 26.

Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

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http://dx.doi.org/10.1016/j.redox.2012.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116643PMC
April 2015

Disabling the platelet's brakes to promote thrombosis.

Blood 2015 Apr;125(17):2591-3

MEDICAL COLLEGE OF WISCONSIN.

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http://dx.doi.org/10.1182/blood-2015-03-630822DOI Listing
April 2015

Hyper-inflammation and skin destruction mediated by rosiglitazone activation of macrophages in IL-6 deficiency.

J Invest Dermatol 2015 Feb 3;135(2):389-399. Epub 2014 Sep 3.

Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291681PMC
February 2015

Thymidine phosphorylase participates in platelet signaling and promotes thrombosis.

Circ Res 2014 Dec 6;115(12):997-1006. Epub 2014 Oct 6.

From the Department of Cellular and Molecular Medicine, Lerner Research Institute, The Cleveland Clinic, OH (W.L., T.M.M.); Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, OH (W.L., T.M.M.); Instituto de Quimica Medica, Consejo Superior De Investigaciones Cientificas (IQM-CSIC), Madrid, Spain (A.G.,M.-J.P.-P.); Department of Biological Sciences, Case Western Reserve University, Cleveland, OH (H.Y.); Department of Neurology, Columbia University Medical Center, New York, NY (M.H.); and Department of Medicine, Medical College of Wisconsin and Blood Research Institute, Blood Center of Wisconsin, Milwaukee (R.L.S.).

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http://circres.ahajournals.org/content/early/2014/10/06/CIRC
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http://circres.ahajournals.org/cgi/doi/10.1161/CIRCRESAHA.11
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http://dx.doi.org/10.1161/CIRCRESAHA.115.304591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258140PMC
December 2014

Platelet CD36 links not only α-granule-derived proteins to thrombus stability but also metabolic and oxidant stress to a prothrombotic phenotype.

Arterioscler Thromb Vasc Biol 2014 Jun;34(6):1120-1

From the Department of Medicine, Medical College of Wisconsin and Blood Research Institute, Blood Center of Wisconsin, Milwaukee.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.114.303687
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http://dx.doi.org/10.1161/ATVBAHA.114.303687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629480PMC
June 2014

Proteasome proteolysis supports stimulated platelet function and thrombosis.

Arterioscler Thromb Vasc Biol 2014 Jan 31;34(1):160-8. Epub 2013 Oct 31.

From the Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland, OH (N.G., W.L., B.W., R.L.S., T.M.M.); and Department of Biological Geological and Environmental Sciences, Cleveland State University, Cleveland, OH (N.G., T.M.M.).

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.113.302116
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http://dx.doi.org/10.1161/ATVBAHA.113.302116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059534PMC
January 2014

Lipopolysaccharide stimulates platelets through an IL-1β autocrine loop.

J Immunol 2013 Nov 30;191(10):5196-203. Epub 2013 Sep 30.

Department of Cellular & Molecular Medicine, Lerner Research Institute, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1300354
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http://dx.doi.org/10.4049/jimmunol.1300354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818355PMC
November 2013

Vav Guanine nucleotide exchange factors regulate atherosclerotic lesion development in mice.

Arterioscler Thromb Vasc Biol 2013 Sep 3;33(9):2053-7. Epub 2013 Jul 3.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

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http://dx.doi.org/10.1161/ATVBAHA.113.301414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864095PMC
September 2013

Thrombospondin-1 modulates VEGF signaling via CD36 by recruiting SHP-1 to VEGFR2 complex in microvascular endothelial cells.

Blood 2013 Sep 29;122(10):1822-32. Epub 2013 Jul 29.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland OH, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2013-01-48
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http://dx.doi.org/10.1182/blood-2013-01-482315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765061PMC
September 2013

Nicotine potentiates proatherogenic effects of oxLDL by stimulating and upregulating macrophage CD36 signaling.

Am J Physiol Heart Circ Physiol 2013 Aug 7;305(4):H563-74. Epub 2013 Jun 7.

Department of Physiology, Liaoning Medical University, Jinzhou, Peoples Republic of China;

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http://dx.doi.org/10.1152/ajpheart.00042.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891251PMC
August 2013

Molecular basis of antiangiogenic thrombospondin-1 type 1 repeat domain interactions with CD36.

Arterioscler Thromb Vasc Biol 2013 Jul 2;33(7):1655-62. Epub 2013 May 2.

Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

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http://dx.doi.org/10.1161/ATVBAHA.113.301523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737738PMC
July 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

Authors:
Santhi K Ganesh Vinicius Tragante Wei Guo Yiran Guo Matthew B Lanktree Erin N Smith Toby Johnson Berta Almoguera Castillo John Barnard Jens Baumert Yen-Pei Christy Chang Clara C Elbers Martin Farrall Mary E Fischer Nora Franceschini Tom R Gaunt Johannes M I H Gho Christian Gieger Yan Gong Aaron Isaacs Marcus E Kleber Irene Mateo Leach Caitrin W McDonough Matthijs F L Meijs Olle Mellander Cliona M Molony Ilja M Nolte Sandosh Padmanabhan Tom S Price Ramakrishnan Rajagopalan Jonathan Shaffer Sonia Shah Haiqing Shen Nicole Soranzo Peter J van der Most Erik P A Van Iperen Jessica Van Setten Jessic A Van Setten Judith M Vonk Li Zhang Amber L Beitelshees Gerald S Berenson Deepak L Bhatt Jolanda M A Boer Eric Boerwinkle Ben Burkley Amber Burt Aravinda Chakravarti Wei Chen Rhonda M Cooper-Dehoff Sean P Curtis Albert Dreisbach David Duggan Georg B Ehret Richard R Fabsitz Myriam Fornage Ervin Fox Clement E Furlong Ron T Gansevoort Marten H Hofker G Kees Hovingh Susan A Kirkland Kandice Kottke-Marchant Abdullah Kutlar Andrea Z Lacroix Taimour Y Langaee Yun R Li Honghuang Lin Kiang Liu Steffi Maiwald Rainer Malik Gurunathan Murugesan Christopher Newton-Cheh Jeffery R O'Connell N Charlotte Onland-Moret Willem H Ouwehand Walter Palmas Brenda W Penninx Carl J Pepine Mary Pettinger Joseph F Polak Vasan S Ramachandran Jane Ranchalis Susan Redline Paul M Ridker Lynda M Rose Hubert Scharnag Nicholas J Schork Daichi Shimbo Alan R Shuldiner Sathanur R Srinivasan Ronald P Stolk Herman A Taylor Barbara Thorand Mieke D Trip Cornelia M van Duijn W Monique Verschuren Cisca Wijmenga Bernhard R Winkelmann Sharon Wyatt J Hunter Young Bernhard O Boehm Mark J Caulfield Daniel I Chasman Karina W Davidson Pieter A Doevendans Garret A Fitzgerald John G Gums Hakon Hakonarson Hans L Hillege Thomas Illig Gail P Jarvik Julie A Johnson John J P Kastelein Wolfgang Koenig Winfried März Braxton D Mitchell Sarah S Murray Albertine J Oldehinkel Daniel J Rader Muredach P Reilly Alex P Reiner Eric E Schadt Roy L Silverstein Harold Snieder Alice V Stanton André G Uitterlinden Pim van der Harst Yvonne T van der Schouw Nilesh J Samani Andrew D Johnson Patricia B Munroe Paul I W de Bakker Xiaofeng Zhu Daniel Levy Brendan J Keating Folkert W Asselbergs

Hum Mol Genet 2013 Apr 8;22(8):1663-78. Epub 2013 Jan 8.

Division of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, MI, USA.

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http://hmg.oxfordjournals.org/content/22/8/1663.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/dds555
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http://dx.doi.org/10.1093/hmg/dds555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657476PMC
April 2013

Context dependent role of the CD36--thrombospondin--histidine-rich glycoprotein axis in tumor angiogenesis and growth.

PLoS One 2012 10;7(7):e40033. Epub 2012 Jul 10.

Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040033PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393734PMC
March 2013

CD36 and Na/K-ATPase-α1 form a proinflammatory signaling loop in kidney.

Hypertension 2013 Jan 19;61(1):216-24. Epub 2012 Nov 19.

Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.112.198770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521864PMC
January 2013

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

Authors:
Folkert W Asselbergs Yiran Guo Erik P A van Iperen Suthesh Sivapalaratnam Vinicius Tragante Matthew B Lanktree Leslie A Lange Berta Almoguera Yolande E Appelman John Barnard Jens Baumert Amber L Beitelshees Tushar R Bhangale Yii-Der Ida Chen Tom R Gaunt Yan Gong Jemma C Hopewell Toby Johnson Marcus E Kleber Taimour Y Langaee Mingyao Li Yun R Li Kiang Liu Caitrin W McDonough Matthijs F L Meijs Rita P S Middelberg Kiran Musunuru Christopher P Nelson Jeffery R O'Connell Sandosh Padmanabhan James S Pankow Nathan Pankratz Suzanne Rafelt Ramakrishnan Rajagopalan Simon P R Romaine Nicholas J Schork Jonathan Shaffer Haiqing Shen Erin N Smith Sam E Tischfield Peter J van der Most Jana V van Vliet-Ostaptchouk Niek Verweij Kelly A Volcik Li Zhang Kent R Bailey Kristian M Bailey Florianne Bauer Jolanda M A Boer Peter S Braund Amber Burt Paul R Burton Sarah G Buxbaum Wei Chen Rhonda M Cooper-Dehoff L Adrienne Cupples Jonas S deJong Christian Delles David Duggan Myriam Fornage Clement E Furlong Nicole Glazer John G Gums Claire Hastie Michael V Holmes Thomas Illig Susan A Kirkland Mika Kivimaki Ronald Klein Barbara E Klein Charles Kooperberg Kandice Kottke-Marchant Meena Kumari Andrea Z LaCroix Laya Mallela Gurunathan Murugesan Jose Ordovas Willem H Ouwehand Wendy S Post Richa Saxena Hubert Scharnagl Pamela J Schreiner Tina Shah Denis C Shields Daichi Shimbo Sathanur R Srinivasan Ronald P Stolk Daniel I Swerdlow Herman A Taylor Eric J Topol Elina Toskala Joost L van Pelt Jessica van Setten Salim Yusuf John C Whittaker A H Zwinderman Sonia S Anand Anthony J Balmforth Gerald S Berenson Connie R Bezzina Bernhard O Boehm Eric Boerwinkle Juan P Casas Mark J Caulfield Robert Clarke John M Connell Karen J Cruickshanks Karina W Davidson Ian N M Day Paul I W de Bakker Pieter A Doevendans Anna F Dominiczak Alistair S Hall Catharina A Hartman Christian Hengstenberg Hans L Hillege Marten H Hofker Steve E Humphries Gail P Jarvik Julie A Johnson Bernhard M Kaess Sekar Kathiresan Wolfgang Koenig Debbie A Lawlor Winfried März Olle Melander Braxton D Mitchell Grant W Montgomery Patricia B Munroe Sarah S Murray Stephen J Newhouse N Charlotte Onland-Moret Neil Poulter Bruce Psaty Susan Redline Stephen S Rich Jerome I Rotter Heribert Schunkert Peter Sever Alan R Shuldiner Roy L Silverstein Alice Stanton Barbara Thorand Mieke D Trip Michael Y Tsai Pim van der Harst Ellen van der Schoot Yvonne T van der Schouw W M Monique Verschuren Hugh Watkins Arthur A M Wilde Bruce H R Wolffenbuttel John B Whitfield G Kees Hovingh Christie M Ballantyne Cisca Wijmenga Muredach P Reilly Nicholas G Martin James G Wilson Daniel J Rader Nilesh J Samani Alex P Reiner Robert A Hegele John J P Kastelein Aroon D Hingorani Philippa J Talmud Hakon Hakonarson Clara C Elbers Brendan J Keating Fotios Drenos

Am J Hum Genet 2012 Nov 11;91(5):823-38. Epub 2012 Oct 11.

Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.ajhg.2012.08.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487124PMC
November 2012

Insulin promotes macrophage foam cell formation: potential implications in diabetes-related atherosclerosis.

Lab Invest 2012 Aug 23;92(8):1171-80. Epub 2012 Apr 23.

Department of Molecular Medicine, Ewha Womans University School of Medicine, Seoul, Republic of Korea.

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http://www.nature.com/articles/labinvest201274
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http://dx.doi.org/10.1038/labinvest.2012.74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407326PMC
August 2012

Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion.

Mol Biol Cell 2012 Aug 20;23(16):3057-68. Epub 2012 Jun 20.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1091/mbc.E11-12-1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418302PMC
August 2012

Advanced glycation end products induce a prothrombotic phenotype in mice via interaction with platelet CD36.

Blood 2012 Jun 19;119(25):6136-44. Epub 2012 Mar 19.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-10-38
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http://dx.doi.org/10.1182/blood-2011-10-387506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383021PMC
June 2012

CD36 ectodomain phosphorylation blocks thrombospondin-1 binding: structure-function relationships and regulation by protein kinase C.

Arterioscler Thromb Vasc Biol 2012 Mar 12;32(3):760-7. Epub 2012 Jan 12.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.111.242511
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http://dx.doi.org/10.1161/ATVBAHA.111.242511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298081PMC
March 2012

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.

Authors:
Richa Saxena Clara C Elbers Yiran Guo Inga Peter Tom R Gaunt Jessica L Mega Matthew B Lanktree Archana Tare Berta Almoguera Castillo Yun R Li Toby Johnson Marcel Bruinenberg Diane Gilbert-Diamond Ramakrishnan Rajagopalan Benjamin F Voight Ashok Balasubramanyam John Barnard Florianne Bauer Jens Baumert Tushar Bhangale Bernhard O Böhm Peter S Braund Paul R Burton Hareesh R Chandrupatla Robert Clarke Rhonda M Cooper-DeHoff Errol D Crook George Davey-Smith Ian N Day Anthonius de Boer Mark C H de Groot Fotios Drenos Jane Ferguson Caroline S Fox Clement E Furlong Quince Gibson Christian Gieger Lisa A Gilhuijs-Pederson Joseph T Glessner Anuj Goel Yan Gong Struan F A Grant Diederick E Grobbee Claire Hastie Steve E Humphries Cecilia E Kim Mika Kivimaki Marcus Kleber Christa Meisinger Meena Kumari Taimour Y Langaee Debbie A Lawlor Mingyao Li Maximilian T Lobmeyer Anke-Hilse Maitland-van der Zee Matthijs F L Meijs Cliona M Molony David A Morrow Gurunathan Murugesan Solomon K Musani Christopher P Nelson Stephen J Newhouse Jeffery R O'Connell Sandosh Padmanabhan Jutta Palmen Sanjey R Patel Carl J Pepine Mary Pettinger Thomas S Price Suzanne Rafelt Jane Ranchalis Asif Rasheed Elisabeth Rosenthal Ingo Ruczinski Sonia Shah Haiqing Shen Günther Silbernagel Erin N Smith Annemieke W M Spijkerman Alice Stanton Michael W Steffes Barbara Thorand Mieke Trip Pim van der Harst Daphne L van der A Erik P A van Iperen Jessica van Setten Jana V van Vliet-Ostaptchouk Niek Verweij Bruce H R Wolffenbuttel Taylor Young M Hadi Zafarmand Joseph M Zmuda Michael Boehnke David Altshuler Mark McCarthy W H Linda Kao James S Pankow Thomas P Cappola Peter Sever Neil Poulter Mark Caulfield Anna Dominiczak Denis C Shields Deepak L Bhatt Deepak Bhatt Li Zhang Sean P Curtis John Danesh Juan P Casas Yvonne T van der Schouw N Charlotte Onland-Moret Pieter A Doevendans Gerald W Dorn Martin Farrall Garret A FitzGerald Anders Hamsten Robert Hegele Aroon D Hingorani Marten H Hofker Gordon S Huggins Thomas Illig Gail P Jarvik Julie A Johnson Olaf H Klungel William C Knowler Wolfgang Koenig Winfried März James B Meigs Olle Melander Patricia B Munroe Braxton D Mitchell Susan J Bielinski Daniel J Rader Muredach P Reilly Stephen S Rich Jerome I Rotter Danish Saleheen Nilesh J Samani Eric E Schadt Alan R Shuldiner Roy Silverstein Kandice Kottke-Marchant Philippa J Talmud Hugh Watkins Folkert W Asselbergs Folkert Asselbergs Paul I W de Bakker Jeanne McCaffery Cisca Wijmenga Marc S Sabatine James G Wilson Alex Reiner Donald W Bowden Hakon Hakonarson David S Siscovick Brendan J Keating

Am J Hum Genet 2012 Mar 9;90(3):410-25. Epub 2012 Feb 9.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, 02114, USA.

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http://dx.doi.org/10.1016/j.ajhg.2011.12.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309185PMC
March 2012

Teaching an old dog new tricks: potential antiatherothrombotic use for statins.

J Clin Invest 2012 Feb 3;122(2):478-81. Epub 2012 Jan 3.

Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

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http://www.jci.org/articles/view/61857
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http://dx.doi.org/10.1172/JCI61857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266801PMC
February 2012

Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.

Protein Expr Purif 2011 Dec 29;80(2):253-9. Epub 2011 Jul 29.

Department of Cell Biology, NC10, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.pep.2011.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195888PMC
December 2011

Vav protein guanine nucleotide exchange factor regulates CD36 protein-mediated macrophage foam cell formation via calcium and dynamin-dependent processes.

J Biol Chem 2011 Oct 24;286(41):36011-9. Epub 2011 Aug 24.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1074/jbc.M111.265082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195569PMC
October 2011

Lysophosphatidic acid suppresses endothelial cell CD36 expression and promotes angiogenesis via a PKD-1-dependent signaling pathway.

Blood 2011 Jun 25;117(22):6036-45. Epub 2011 Mar 25.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1182/blood-2010-12-326017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112047PMC
June 2011

Vav guanine nucleotide exchange factors link hyperlipidemia and a prothrombotic state.

Blood 2011 May 22;117(21):5744-50. Epub 2011 Mar 22.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

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http://dx.doi.org/10.1182/blood-2009-01-201970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110031PMC
May 2011

Vav family Rho guanine nucleotide exchange factors regulate CD36-mediated macrophage foam cell formation.

J Biol Chem 2011 Mar 5;286(9):7010-7. Epub 2011 Jan 5.

Department of Cell Biology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1074/jbc.M110.192450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044957PMC
March 2011

A CD36-dependent pathway enhances macrophage and adipose tissue inflammation and impairs insulin signalling.

Cardiovasc Res 2011 Feb 18;89(3):604-13. Epub 2010 Nov 18.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1093/cvr/cvq360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028977PMC
February 2011

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

Authors:
Matthew B Lanktree Yiran Guo Muhammed Murtaza Joseph T Glessner Swneke D Bailey N Charlotte Onland-Moret Guillaume Lettre Halit Ongen Ramakrishnan Rajagopalan Toby Johnson Haiqing Shen Christopher P Nelson Norman Klopp Jens Baumert Sandosh Padmanabhan Nathan Pankratz James S Pankow Sonia Shah Kira Taylor John Barnard Bas J Peters Cliona M Maloney Maximilian T Lobmeyer Alice Stanton M Hadi Zafarmand Simon P R Romaine Amar Mehta Erik P A van Iperen Yan Gong Tom S Price Erin N Smith Cecilia E Kim Yun R Li Folkert W Asselbergs Larry D Atwood Kristian M Bailey Deepak Bhatt Florianne Bauer Elijah R Behr Tushar Bhangale Jolanda M A Boer Bernhard O Boehm Jonathan P Bradfield Morris Brown Peter S Braund Paul R Burton Cara Carty Hareesh R Chandrupatla Wei Chen John Connell Chrysoula Dalgeorgou Anthonius de Boer Fotios Drenos Clara C Elbers James C Fang Caroline S Fox Edward C Frackelton Barry Fuchs Clement E Furlong Quince Gibson Christian Gieger Anuj Goel Diederik E Grobbee Claire Hastie Philip J Howard Guan-Hua Huang W Craig Johnson Qing Li Marcus E Kleber Barbara E K Klein Ronald Klein Charles Kooperberg Bonnie Ky Andrea Lacroix Paul Lanken Mark Lathrop Mingyao Li Vanessa Marshall Olle Melander Frank D Mentch Nuala J Meyer Keri L Monda Alexandre Montpetit Gurunathan Murugesan Karen Nakayama Dave Nondahl Abiodun Onipinla Suzanne Rafelt Stephen J Newhouse F George Otieno Sanjey R Patel Mary E Putt Santiago Rodriguez Radwan N Safa Douglas B Sawyer Pamela J Schreiner Claire Simpson Suthesh Sivapalaratnam Sathanur R Srinivasan Christine Suver Gary Swergold Nancy K Sweitzer Kelly A Thomas Barbara Thorand Nicholas J Timpson Sam Tischfield Martin Tobin Maciej Tomaszewski Maciej Tomaszweski W M Monique Verschuren Chris Wallace Bernhard Winkelmann Haitao Zhang Dongling Zheng Li Zhang Joseph M Zmuda Robert Clarke Anthony J Balmforth John Danesh Ian N Day Nicholas J Schork Paul I W de Bakker Christian Delles David Duggan Aroon D Hingorani Joel N Hirschhorn Marten H Hofker Steve E Humphries Mika Kivimaki Debbie A Lawlor Kandice Kottke-Marchant Jessica L Mega Braxton D Mitchell David A Morrow Jutta Palmen Susan Redline Denis C Shields Alan R Shuldiner Patrick M Sleiman George Davey Smith Martin Farrall Yalda Jamshidi David C Christiani Juan P Casas Alistair S Hall Pieter A Doevendans Jason D Christie Gerald S Berenson Sarah S Murray Thomas Illig Gerald W Dorn Thomas P Cappola Eric Boerwinkle Peter Sever Daniel J Rader Muredach P Reilly Mark Caulfield Philippa J Talmud Eric Topol James C Engert Kai Wang Anna Dominiczak Anders Hamsten Sean P Curtis Roy L Silverstein Leslie A Lange Marc S Sabatine Mieke Trip Danish Saleheen John F Peden Karen J Cruickshanks Winfried März Jeffrey R O'Connell Olaf H Klungel Cisca Wijmenga Anke Hilse Maitland-van der Zee Eric E Schadt Julie A Johnson Gail P Jarvik George J Papanicolaou Struan F A Grant Patricia B Munroe Kari E North Nilesh J Samani Wolfgang Koenig Tom R Gaunt Sonia S Anand Yvonne T van der Schouw Nicole Soranzo Garret A Fitzgerald Alex Reiner Robert A Hegele Hakon Hakonarson Brendan J Keating

Am J Hum Genet 2011 Jan 30;88(1):6-18. Epub 2010 Dec 30.

Department of Medicine and Biochemistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.

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http://dx.doi.org/10.1016/j.ajhg.2010.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014369PMC
January 2011

Mechanisms of cell signaling by the scavenger receptor CD36: implications in atherosclerosis and thrombosis.

Trans Am Clin Climatol Assoc 2010 ;121:206-20

Department of Cell Biology, Lerner Research Institute, NC10, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917163PMC
December 2010

CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs.

J Clin Invest 2010 Nov 11;120(11):3996-4006. Epub 2010 Oct 11.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1172/JCI42823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964976PMC
November 2010

A novel broadband impedance method for detection of cell-derived microparticles.

Biosens Bioelectron 2010 Oct 3;26(2):444-51. Epub 2010 Aug 3.

The Cleveland Clinic Foundation, Department of Biomedical Engineering/ND20, 9500 Euclid Ave., Cleveland, OH 44195, United States.

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http://dx.doi.org/10.1016/j.bios.2010.07.094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946439PMC
October 2010

Histidine-rich glycoprotein modulates the anti-angiogenic effects of vasculostatin.

Am J Pathol 2010 Apr 18;176(4):2039-50. Epub 2010 Feb 18.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.2353/ajpath.2010.090782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843491PMC
April 2010

Surveillance for deep vein thrombosis and pulmonary embolism: recommendations from a national workshop.

Am J Prev Med 2010 Apr;38(4 Suppl):S502-9

College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.

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http://dx.doi.org/10.1016/j.amepre.2010.01.010DOI Listing
April 2010

Lipid-induced insulin resistance is associated with increased monocyte expression of scavenger receptor CD36 and internalization of oxidized LDL.

Obesity (Silver Spring) 2009 Dec 11;17(12):2142-8. Epub 2009 Jun 11.

Department of Endocrinology, Diabetes and Metabolism, Endocrinology Institute, Lerner Research Institute; Cleveland Clinic Foundation, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1038/oby.2009.179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836489PMC
December 2009

Type 2 scavenger receptor CD36 in platelet activation: the role of hyperlipemia and oxidative stress.

Clin Lipidol 2009 Dec;4(6):767

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, 9500 Euclid Ave 44195, NC10, Cleveland, OH, USA Tel.: +1 216 444 5220.

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http://dx.doi.org/10.2217/clp.09.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819200PMC
December 2009

TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.

Cell Immunol 2009 11;258(1):29-37. Epub 2009 Apr 11.

Department of Pathology, Case Western Reserve University School of Medicine/University Hospitals Case Medical Center, Cleveland, OH 44106, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000887490900048
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http://dx.doi.org/10.1016/j.cellimm.2009.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730726PMC
June 2009

CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior.

Sci Signal 2009 May 26;2(72):re3. Epub 2009 May 26.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA.

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http://stke.sciencemag.org/cgi/doi/10.1126/scisignal.272re3
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http://dx.doi.org/10.1126/scisignal.272re3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811062PMC
May 2009

Inflammation, atherosclerosis, and arterial thrombosis: role of the scavenger receptor CD36.

Cleve Clin J Med 2009 Apr;76 Suppl 2:S27-30

Department of Cell Biology, Cleveland Clinic, 9500 Euclid Avenue, NC10, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.3949/ccjm.76.s2.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810530PMC
April 2009

Deficiency of LRP8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis.

Thromb Res 2009 Feb 15;123(4):644-52. Epub 2008 Aug 15.

Department of Cell Biology, Cleveland Clinic, Cleveland, OH; Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, OH, USA.

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http://dx.doi.org/10.1016/j.thromres.2008.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661626PMC
February 2009

Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism.

Cancer Res 2009 Feb 27;69(3):1212-20. Epub 2009 Jan 27.

Department of Neurosurgery, Laboratory of Molecular Neuro-Oncology, Winship Cancer Institute, Emory University, School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659670PMC
February 2009

Thrombospondin-1-induced apoptosis of brain microvascular endothelial cells can be mediated by TNF-R1.

J Cell Physiol 2009 Jan;218(1):94-103

Division of Neuropathology, Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1002/jcp.21570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597846PMC
January 2009

CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima.

J Clin Invest 2009 Jan 8;119(1):136-45. Epub 2008 Dec 8.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1172/JCI35535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613464PMC
January 2009

A specific CD36-dependent signaling pathway is required for platelet activation by oxidized low-density lipoprotein.

Circ Res 2008 Jun 22;102(12):1512-9. Epub 2008 May 22.

Program in Cell Biology, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.108.172064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749986PMC
June 2008

Platelet CD36 mediates interactions with endothelial cell-derived microparticles and contributes to thrombosis in mice.

J Clin Invest 2008 May;118(5):1934-43

Department of Biological, Geological, and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1172/JCI34904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323190PMC
May 2008

CD36-TSP-HRGP interactions in the regulation of angiogenesis.

Curr Pharm Des 2007 ;13(35):3559-67

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.2174/138161207782794185DOI Listing
February 2008

Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis.

Gastroenterology 2008 Feb 28;134(2):556-67. Epub 2007 Nov 28.

Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1053/j.gastro.2007.11.037DOI Listing
February 2008

CD36: implications in cardiovascular disease.

Int J Biochem Cell Biol 2007 23;39(11):2012-30. Epub 2007 Mar 23.

Cleveland Clinic, Lerner Research Institute, Department of Cell Biology, NC-10, 9500 Euclid Avenue, Cleveland, OH 44195, United States.

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http://dx.doi.org/10.1016/j.biocel.2007.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034445PMC
December 2007

Venous thrombosis in the elderly: more questions than answers.

Blood 2007 Nov 7;110(9):3097-101. Epub 2007 Aug 7.

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2007-06-09
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http://dx.doi.org/10.1182/blood-2007-06-096545DOI Listing
November 2007

Continued inhibition of atherosclerotic lesion development in long term Western diet fed CD36o /apoEo mice .

Atherosclerosis 2007 May 17;192(1):123-30. Epub 2006 Aug 17.

Department of Medicine, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, United States.

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http://dx.doi.org/10.1016/j.atherosclerosis.2006.07.015DOI Listing
May 2007

Neprilysin inhibits angiogenesis via proteolysis of fibroblast growth factor-2.

J Biol Chem 2006 Nov 28;281(44):33597-605. Epub 2006 Aug 28.

Urologic Oncology Research Laboratory, Department of Urology, Weil Medical College of Cornell University-New York Presbyterian Hospital, New York, NY 10021, USA.

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http://dx.doi.org/10.1074/jbc.M602490200DOI Listing
November 2006

Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells.

J Exp Med 2006 Nov 13;203(12):2613-25. Epub 2006 Nov 13.

Department of Cell Biology, Center for Cardiovascular Diagnostics and Prevention, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://www.jem.org/lookup/doi/10.1084/jem.20060370
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http://dx.doi.org/10.1084/jem.20060370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118161PMC
November 2006

A CD36-dependent signaling cascade is necessary for macrophage foam cell formation.

Cell Metab 2006 Sep;4(3):211-21

Department of Cell Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1016/j.cmet.2006.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855263PMC
September 2006

Requirements for apoptotic cell contact in regulation of macrophage responses.

J Immunol 2006 Sep;177(6):4047-54

Medical Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.177.6.4047DOI Listing
September 2006

A novel isoform of human Golgi complex-localized glycoprotein-1 (also known as E-selectin ligand-1, MG-160 and cysteine-rich fibroblast growth factor receptor) targets differential subcellular localization.

J Cell Sci 2005 Apr 29;118(Pt 8):1725-31. Epub 2005 Mar 29.

Department of Medicine, Division of Hematology and Medical Oncology, Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.02310
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April 2005

Stem cell transplantation reveals that absence of macrophage CD36 is protective against atherosclerosis.

Arterioscler Thromb Vasc Biol 2004 Dec 14;24(12):2333-8. Epub 2004 Oct 14.

Department of Cell Biology, Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1161/01.ATV.0000148007.06370.68DOI Listing
December 2004

Identification of the growth hormone-releasing peptide binding site in CD36: a photoaffinity cross-linking study.

Biochem J 2004 Sep;382(Pt 2):417-24

Faculty of Pharmacy, Université de Montréal, C.P. 6128, Succursale Centre-ville, Montreal, Quebec, H3C 3J7 Canada.

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http://dx.doi.org/10.1042/BJ20040036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133797PMC
September 2004

Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo.

J Clin Invest 2004 Jan;113(1):38-48

Department of Cell and Developmental Biology, Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://www.jci.org/articles/view/19684
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http://dx.doi.org/10.1172/JCI19684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC300771PMC
January 2004

CD36 mediates the phagocytosis of Plasmodium falciparum-infected erythrocytes by rodent macrophages.

J Infect Dis 2004 Jan 9;189(2):204-13. Epub 2004 Jan 9.

Department of Medicine, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1086/380764DOI Listing
January 2004

CD36: a critical anti-angiogenic receptor.

Front Biosci 2003 Sep 1;8:s874-82. Epub 2003 Sep 1.

Division of Hematology-Oncology, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.2741/1168DOI Listing
September 2003

Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR.

Cancer Cell 2003 Feb;3(2):131-43

Laboratory of Viral Oncogenesis, Department of Medicine, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA.

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February 2003

The face of TSR revealed: an extracellular signaling domain is exposed.

J Cell Biol 2002 Oct 28;159(2):203-6. Epub 2002 Oct 28.

Division of Hematology and Medical Oncology, Department of Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1083/jcb.200209138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173053PMC
October 2002

Hematology Grants Workshop-2000.

Hematology Am Soc Hematol Educ Program 2000 :424-437

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January 2000