Rotem Sorek

Rotem Sorek

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Rotem Sorek

Publications by authors named "Rotem Sorek"

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The pan-immune system of bacteria: antiviral defence as a community resource.

Nat Rev Microbiol 2020 Feb 6;18(2):113-119. Epub 2019 Nov 6.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1038/s41579-019-0278-2DOI Listing
February 2020

Cyclic GMP-AMP signalling protects bacteria against viral infection.

Nature 2019 10 18;574(7780):691-695. Epub 2019 Sep 18.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1038/s41586-019-1605-5DOI Listing
October 2019

Widespread Utilization of Peptide Communication in Phages Infecting Soil and Pathogenic Bacteria.

Cell Host Microbe 2019 05;25(5):746-755.e5

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2019.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986904PMC
May 2019

Successful Brincidofovir Treatment of Metagenomics-detected Adenovirus Infection in a Severely Ill Signal Transducer and Activator of Transcription-1-deficient Patient.

Pediatr Infect Dis J 2019 03;38(3):297-299

Department of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://Insights.ovid.com/crossref?an=00006454-900000000-9661
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http://dx.doi.org/10.1097/INF.0000000000002090DOI Listing
March 2019

HflXr, a homolog of a ribosome-splitting factor, mediates antibiotic resistance.

Proc Natl Acad Sci U S A 2018 12 13;115(52):13359-13364. Epub 2018 Dec 13.

Département de Biologie Cellulaire et Infection, Unité des Interactions Bactéries-Cellules, Institut Pasteur, F-75015 Paris, France;

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http://dx.doi.org/10.1073/pnas.1810555115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310831PMC
December 2018

Bacterial Noncoding RNAs Excised from within Protein-Coding Transcripts.

mBio 2018 09 25;9(5). Epub 2018 Sep 25.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

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http://dx.doi.org/10.1128/mBio.01730-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156199PMC
September 2018

High-resolution RNA 3'-ends mapping of bacterial Rho-dependent transcripts.

Nucleic Acids Res 2018 07;46(13):6797-6805

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1093/nar/gky274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061677PMC
July 2018

Viruses cooperate to defeat bacteria.

Nature 2018 07;559(7715):482-484

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http://dx.doi.org/10.1038/d41586-018-05762-1DOI Listing
July 2018

Extensive reshaping of bacterial operons by programmed mRNA decay.

PLoS Genet 2018 04 18;14(4):e1007354. Epub 2018 Apr 18.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1371/journal.pgen.1007354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927463PMC
April 2018

Systematic discovery of antiphage defense systems in the microbial pangenome.

Science 2018 03 25;359(6379). Epub 2018 Jan 25.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://www.sciencemag.org/lookup/doi/10.1126/science.aar4120
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http://dx.doi.org/10.1126/science.aar4120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387622PMC
March 2018

Contemporary Phage Biology: From Classic Models to New Insights.

Cell 2018 03;172(6):1260-1270

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.10.045DOI Listing
March 2018

DISARM is a widespread bacterial defence system with broad anti-phage activities.

Nat Microbiol 2018 Jan 30;3(1):90-98. Epub 2017 Oct 30.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1038/s41564-017-0051-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739279PMC
January 2018

Intracellular signaling in CRISPR-Cas defense.

Science 2017 08;357(6351):550-551

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1126/science.aao2210DOI Listing
August 2017

Regulation of antibiotic-resistance by non-coding RNAs in bacteria.

Curr Opin Microbiol 2017 Apr 14;36:111-117. Epub 2017 Apr 14.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.mib.2017.02.005DOI Listing
April 2017

Computational prediction of regulatory, premature transcription termination in bacteria.

Nucleic Acids Res 2017 01 29;45(2):886-893. Epub 2016 Aug 29.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel

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http://dx.doi.org/10.1093/nar/gkw749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314783PMC
January 2017

Vesicles Spread Susceptibility to Phages.

Cell 2017 01 12;168(1-2):13-15. Epub 2017 Jan 12.

Department of Molecular Genetics, Weizmann Institute of Science, 76100 Rehovot, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.12.035DOI Listing
January 2017

Communication between viruses guides lysis-lysogeny decisions.

Nature 2017 01 18;541(7638):488-493. Epub 2017 Jan 18.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.

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http://dx.doi.org/10.1038/nature21049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378303PMC
January 2017

Optimality and sub-optimality in a bacterial growth law.

Nat Commun 2017 01 19;8:14123. Epub 2017 Jan 19.

Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1038/ncomms14123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253639PMC
January 2017

Repeat Size Determination by Two Molecular Rulers in the Type I-E CRISPR Array.

Cell Rep 2016 09;16(11):2811-2818

Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, 69978 Tel Aviv, Israel. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039180PMC
http://dx.doi.org/10.1016/j.celrep.2016.08.043DOI Listing
September 2016

Widespread formation of alternative 3' UTR isoforms via transcription termination in archaea.

Nat Microbiol 2016 08 22;1(10):16143. Epub 2016 Aug 22.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1038/nmicrobiol.2016.143DOI Listing
August 2016

Comparative transcriptomics across the prokaryotic tree of life.

Nucleic Acids Res 2016 Jul 6;44(W1):W46-53. Epub 2016 May 6.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel

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http://dx.doi.org/10.1093/nar/gkw394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987935PMC
July 2016

CRISPR-Cas: Spacer Diversity Determines the Efficiency of Defense.

Curr Biol 2016 07;26(14):R683-5

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2016.05.034DOI Listing
July 2016

Natural selection underlies apparent stress-induced mutagenesis in a bacteriophage infection model.

Nat Microbiol 2016 04 18;1(6):16047. Epub 2016 Apr 18.

Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1038/nmicrobiol.2016.47DOI Listing
April 2016

CRISPR-Cas adaptation: insights into the mechanism of action.

Nat Rev Microbiol 2016 Feb 11;14(2):67-76. Epub 2016 Jan 11.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1038/nrmicro.2015.14DOI Listing
February 2016

CRISPR adaptation biases explain preference for acquisition of foreign DNA.

Nature 2015 Apr 13;520(7548):505-510. Epub 2015 Apr 13.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1038/nature14302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561520PMC
April 2015

Pregnancy-associated listeriosis: clinical characteristics and geospatial analysis of a 10-year period in Israel.

Clin Infect Dis 2014 Oct 27;59(7):953-61. Epub 2014 Jun 27.

Department of Clinical Microbiology and Infectious Diseases, Hadassah Hebrew University Medical Center, Ein Kerem.

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http://dx.doi.org/10.1093/cid/ciu504DOI Listing
October 2014

High-resolution metagenomics.

Nat Biotechnol 2014 Aug;32(8):750-1

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1038/nbt.2962DOI Listing
August 2014

Riboswitches. Sequestration of a two-component response regulator by a riboswitch-regulated noncoding RNA.

Science 2014 Aug;345(6199):940-3

Unité des Interactions Bactéries-Cellules, Institut Pasteur, F-75015 Paris, France. INSERM, U604, Paris, F-75015 France. INRA, USC2020, F-75015 Paris, France.

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http://dx.doi.org/10.1126/science.1255083DOI Listing
August 2014

CRISPR-mediated adaptive immune systems in bacteria and archaea.

Annu Rev Biochem 2013 11;82:237-66. Epub 2013 Mar 11.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1146/annurev-biochem-072911-172315DOI Listing
November 2013

Computational evaluation of cellular metabolic costs successfully predicts genes whose expression is deleterious.

Proc Natl Acad Sci U S A 2013 Nov 6;110(47):19166-71. Epub 2013 Nov 6.

The Blavatnik School of Computer Science, Sackler School of Medicine, and Department of Molecular Microbiology and Biotechnology, Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv 69978, Israel.

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http://dx.doi.org/10.1073/pnas.1312361110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839766PMC
November 2013

Correlated occurrence and bypass of frame-shifting insertion-deletions (InDels) to give functional proteins.

PLoS Genet 2013 Oct 24;9(10):e1003882. Epub 2013 Oct 24.

Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1371/journal.pgen.1003882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812077PMC
October 2013

Differential translation tunes uneven production of operon-encoded proteins.

Cell Rep 2013 Sep 5;4(5):938-44. Epub 2013 Sep 5.

Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2013.07.049DOI Listing
September 2013

Transcriptome-wide mapping of 5-methylcytidine RNA modifications in bacteria, archaea, and yeast reveals m5C within archaeal mRNAs.

PLoS Genet 2013 Jun 27;9(6):e1003602. Epub 2013 Jun 27.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1371/journal.pgen.1003602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694839PMC
June 2013

Holding a grudge: persisting anti-phage CRISPR immunity in multiple human gut microbiomes.

RNA Biol 2013 May 25;10(5):900-6. Epub 2013 Feb 25.

Department of Systems Biology, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.4161/rna.23929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737347PMC
May 2013

Discovery of functional toxin/antitoxin systems in bacteria by shotgun cloning.

Mol Cell 2013 Apr 7;50(1):136-48. Epub 2013 Mar 7.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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https://linkinghub.elsevier.com/retrieve/pii/S10972765130012
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http://dx.doi.org/10.1016/j.molcel.2013.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644417PMC
April 2013

PanDaTox: a tool for accelerated metabolic engineering.

Bioengineered 2012 Jul-Aug;3(4):218-21. Epub 2012 Jun 18.

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http://dx.doi.org/10.4161/bioe.20431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476872PMC
March 2013

The excludon: a new concept in bacterial antisense RNA-mediated gene regulation.

Nat Rev Microbiol 2013 02 24;11(2):75-82. Epub 2012 Dec 24.

Unité des Interactions Bactéries-Cellules, Institut National de Santé et de Recherche Médicale (INSERM) U604, Institut Pasteur, and Institut Scientifique de Recherche Agronomique USC2020, Institut Pasteur, Paris F-75015, France.

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http://dx.doi.org/10.1038/nrmicro2934DOI Listing
February 2013

CRISPR targeting reveals a reservoir of common phages associated with the human gut microbiome.

Genome Res 2012 Oct 25;22(10):1985-94. Epub 2012 Jun 25.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1101/gr.138297.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460193PMC
October 2012

The single-nucleotide resolution transcriptome of Pseudomonas aeruginosa grown in body temperature.

PLoS Pathog 2012 Sep 27;8(9):e1002945. Epub 2012 Sep 27.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1371/journal.ppat.1002945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460626PMC
September 2012

Comparative transcriptomics of pathogenic and non-pathogenic Listeria species.

Mol Syst Biol 2012 May 22;8:583. Epub 2012 May 22.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1038/msb.2012.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377988PMC
May 2012

Transcriptome-wide discovery of circular RNAs in Archaea.

Nucleic Acids Res 2012 Apr 2;40(7):3131-42. Epub 2011 Dec 2.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1093/nar/gkr1009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326292PMC
April 2012

A vast collection of microbial genes that are toxic to bacteria.

Genome Res 2012 Apr 1;22(4):802-9. Epub 2012 Feb 1.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1101/gr.133850.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317161PMC
April 2012

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq.

Nature 2012 Apr 29;485(7397):201-6. Epub 2012 Apr 29.

Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer 52621, Israel.

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http://dx.doi.org/10.1038/nature11112DOI Listing
April 2012

RNA-seq analysis of small RNPs in Trypanosoma brucei reveals a rich repertoire of non-coding RNAs.

Nucleic Acids Res 2012 Feb 5;40(3):1282-98. Epub 2011 Oct 5.

The Mina and Everard Goodman Faculty of Life Sciences, and Advanced Materials and Nanotechnology Institute, Bar-Ilan University, Ramat-Gan 52900, Israel.

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http://dx.doi.org/10.1093/nar/gkr786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273796PMC
February 2012

Bacterial genomes: from regulatory complexity to engineering.

Curr Opin Microbiol 2011 Oct 28;14(5):577-8. Epub 2011 Sep 28.

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http://dx.doi.org/10.1016/j.mib.2011.09.006DOI Listing
October 2011

Genomic island variability facilitates Prochlorococcus-virus coexistence.

Nature 2011 Jun 29;474(7353):604-8. Epub 2011 Jun 29.

Faculty of Biology, Technion - Israel Institute of Technology, Haifa 32000, Israel.

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http://www.nature.com/doifinder/10.1038/nature10172
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http://dx.doi.org/10.1038/nature10172DOI Listing
June 2011

The phage-host arms race: shaping the evolution of microbes.

Bioessays 2011 Jan;33(1):43-51

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1002/bies.201000071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274958PMC
January 2011

Mutation detection with next-generation resequencing through a mediator genome.

PLoS One 2010 Dec 31;5(12):e15628. Epub 2010 Dec 31.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015628PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013116PMC
December 2010

Validation of two ribosomal RNA removal methods for microbial metatranscriptomics.

Nat Methods 2010 Oct 19;7(10):807-12. Epub 2010 Sep 19.

Department of Energy Joint Genome Institute, Walnut Creek, California, USA.

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http://dx.doi.org/10.1038/nmeth.1507DOI Listing
October 2010

Self-targeting by CRISPR: gene regulation or autoimmunity?

Trends Genet 2010 Aug 1;26(8):335-40. Epub 2010 Jul 1.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1016/j.tig.2010.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910793PMC
August 2010

A single-base resolution map of an archaeal transcriptome.

Genome Res 2010 Jan 2;20(1):133-41. Epub 2009 Nov 2.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1101/gr.100396.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798825PMC
January 2010

Prokaryotic transcriptomics: a new view on regulation, physiology and pathogenicity.

Nat Rev Genet 2010 01 24;11(1):9-16. Epub 2009 Nov 24.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

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http://dx.doi.org/10.1038/nrg2695DOI Listing
January 2010

The dynamics and time scale of ongoing genomic erosion in symbiotic bacteria.

Science 2009 Jan;323(5912):379-82

Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, AZ 85721, USA.

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http://dx.doi.org/10.1126/science.1167140DOI Listing
January 2009

CRISPR--a widespread system that provides acquired resistance against phages in bacteria and archaea.

Nat Rev Microbiol 2008 Mar;6(3):181-6

Rotem Sorek, Victor Kunin and Philip Hugenholtz are at the Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, California 94598, USA.

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http://dx.doi.org/10.1038/nrmicro1793DOI Listing
March 2008

Evolutionary conservation of sequence and secondary structures in CRISPR repeats.

Genome Biol 2007 ;8(4):R61

DOE Joint Genome Institute, Walnut Creek, CA 94598, USA.

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http://dx.doi.org/10.1186/gb-2007-8-4-r61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1896005PMC
November 2007

Genome-wide experimental determination of barriers to horizontal gene transfer.

Science 2007 Nov 18;318(5855):1449-52. Epub 2007 Oct 18.

Department of Energy, Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA.

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http://dx.doi.org/10.1126/science.1147112DOI Listing
November 2007

The birth of new exons: mechanisms and evolutionary consequences.

Authors:
Rotem Sorek

RNA 2007 Oct 20;13(10):1603-8. Epub 2007 Aug 20.

Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1261/rna.682507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1986822PMC
October 2007

RNA-editing-mediated exon evolution.

Genome Biol 2007 ;8(2):R29

Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel.

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http://dx.doi.org/10.1186/gb-2007-8-2-r29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852406PMC
July 2007

Assessing the number of ancestral alternatively spliced exons in the human genome.

BMC Genomics 2006 Oct 24;7:273. Epub 2006 Oct 24.

Department of Human Genetics, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1186/1471-2164-7-273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635713PMC
October 2006

Transcription-mediated gene fusion in the human genome.

Genome Res 2006 Jan 12;16(1):30-6. Epub 2005 Dec 12.

Compugen Ltd., Tel Aviv 69512, Israel.

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http://dx.doi.org/10.1101/gr.4137606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356126PMC
January 2006

Genomic fossils as a snapshot of the human transcriptome.

Proc Natl Acad Sci U S A 2006 Jan 23;103(5):1364-9. Epub 2006 Jan 23.

Compugen Ltd., 72 Pinchas Rosen Street, Tel Aviv 69512, Israel.

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http://dx.doi.org/10.1073/pnas.0509330103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360558PMC
January 2006

Is there any sense in antisense editing?

Trends Genet 2005 Oct;21(10):544-7

Compugen Ltd, 72 Pinchas Rosen St, Tel-Aviv 69512, Israel.

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http://dx.doi.org/10.1016/j.tig.2005.08.005DOI Listing
October 2005

Accurate identification of alternatively spliced exons using support vector machine.

Bioinformatics 2005 Apr 5;21(7):897-901. Epub 2004 Nov 5.

The Academic College of Tel-Aviv-Yaffo, Tel Aviv 4044, Israel.

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http://dx.doi.org/10.1093/bioinformatics/bti132DOI Listing
April 2005

Naturally occurring antisense: transcriptional leakage or real overlap?

Genome Res 2005 Mar 14;15(3):364-8. Epub 2005 Feb 14.

Compugen Ltd., Tel Aviv 69512 Israel.

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http://dx.doi.org/10.1101/gr.3308405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC551562PMC
March 2005

Is abundant A-to-I RNA editing primate-specific?

Trends Genet 2005 Feb;21(2):77-81

Compugen Ltd, 72 Pinchas Rosen St, Tel-Aviv 69512, Israel.

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http://dx.doi.org/10.1016/j.tig.2004.12.005DOI Listing
February 2005

A non-EST-based method for exon-skipping prediction.

Genome Res 2004 Aug;14(8):1617-23

Department of Human Genetics, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel.

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http://dx.doi.org/10.1101/gr.2572604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC509271PMC
August 2004

Minimal conditions for exonization of intronic sequences: 5' splice site formation in alu exons.

Mol Cell 2004 Apr;14(2):221-31

Department of Human Genetics and Molecular Medicine, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel.

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http://dx.doi.org/10.1016/s1097-2765(04)00181-9DOI Listing
April 2004

How prevalent is functional alternative splicing in the human genome?

Trends Genet 2004 Feb;20(2):68-71

Department of Human Genetics, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel.

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http://dx.doi.org/10.1016/j.tig.2003.12.004DOI Listing
February 2004

In search of antisense.

Trends Biochem Sci 2004 Feb;29(2):88-94

Human Molecular Genetics Unit, Dibit-San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy.

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http://dx.doi.org/10.1016/j.tibs.2003.12.002DOI Listing
February 2004

AluGene: a database of Alu elements incorporated within protein-coding genes.

Nucleic Acids Res 2004 Jan;32(Database issue):D489-92

Department of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv 69978, Israel.

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http://dx.doi.org/10.1093/nar/gkh132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC308866PMC
January 2004

Intronic sequences flanking alternatively spliced exons are conserved between human and mouse.

Authors:
Rotem Sorek Gil Ast

Genome Res 2003 Jul;13(7):1631-7

Department of Human Genetics, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel.

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http://dx.doi.org/10.1101/gr.1208803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC403736PMC
July 2003

The birth of an alternatively spliced exon: 3' splice-site selection in Alu exons.

Science 2003 May;300(5623):1288-91

Department of Human Genetics and Molecular Medicine, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel.

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http://dx.doi.org/10.1126/science.1082588DOI Listing
May 2003

A novel algorithm for computational identification of contaminated EST libraries.

Nucleic Acids Res 2003 Feb;31(3):1067-74

Compugen Ltd, 72 Pinchas Rosen Street, Tel Aviv 69512, Israel.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149192PMC
http://dx.doi.org/10.1093/nar/gkg170DOI Listing
February 2003

Evolutionary dynamics of large numts in the human genome: rarity of independent insertions and abundance of post-insertion duplications.

J Mol Evol 2003 Feb;56(2):169-74

Department of Zoology, George S Wise Faculty of Life Sciences, Tel Aviv University, 69978, Ramat Aviv, Israel.

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http://link.springer.com/10.1007/s00239-002-2390-5
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http://dx.doi.org/10.1007/s00239-002-2390-5DOI Listing
February 2003

Alu-containing exons are alternatively spliced.

Genome Res 2002 Jul;12(7):1060-7

Department of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv 69978, Israel.

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http://dx.doi.org/10.1101/gr.229302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC186627PMC
July 2002