Rossella Libe

Rossella Libe

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Rossella Libe

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Clinical and molecular prognostic factors in adrenocortical carcinoma.

Authors:
Rossella Libé

Minerva Endocrinol 2019 Mar 12;44(1):58-69. Epub 2018 Sep 12.

French Network for Adrenal Cancer, Department of Endocrinology, Cochin Hospital, Paris, France -

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https://www.minervamedica.it/index2.php?show=R07Y2019N01A005
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http://dx.doi.org/10.23736/S0391-1977.18.02900-0DOI Listing
March 2019

18F-FDG PET reveals an adrenocortical carcinoma in a bilateral adrenal multinodular disease.

Endocrine 2019 01 24;63(1):188-189. Epub 2018 Sep 24.

COMETE Cancer Network for Adrenal Cancers, Department of Endocrinology, Cochin Hospital, Paris, France.

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http://link.springer.com/10.1007/s12020-018-1757-3
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http://dx.doi.org/10.1007/s12020-018-1757-3DOI Listing
January 2019

Successful response to pegylated interferon alpha in a patient with recurrent paraganglioma.

Endocr Relat Cancer 2017 02 28;24(2):L7-L11. Epub 2016 Nov 28.

Service d'Endocrinologie et DiabétologieHôpitaux Universitaires de Strasbourg, Strasbourg, France.

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http://dx.doi.org/10.1530/ERC-16-0431DOI Listing
February 2017

[Adrenocortical carcinoma and pregnancy].

Ann Endocrinol (Paris) 2016 Jun 9;77(2):139-47. Epub 2016 May 9.

Department of Endocrinology, Cochin University Hospital, AP-HP, French Adrenal Cancer Network COMETE-Cancer, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France; UMR 8104, institut Cochin, Paris, France.

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http://dx.doi.org/10.1016/j.ando.2016.04.024DOI Listing
June 2016

Adrenocortical carcinoma (ACC): diagnosis, prognosis, and treatment.

Authors:
Rossella Libé

Front Cell Dev Biol 2015 3;3:45. Epub 2015 Jul 3.

Department of Endocrinology, French Network for Adrenal Cancer, Cochin Hospital Paris, France.

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http://dx.doi.org/10.3389/fcell.2015.00045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490795PMC
July 2015

Primary Aldosteronism and ARMC5 Variants.

J Clin Endocrinol Metab 2015 Jun 30;100(6):E900-9. Epub 2015 Mar 30.

Section on Endocrinology and Genetics (M.Z., P.X., F.R.F., A.B., A.G., M.H.S.-R., M.B., S.B.A., S.E., M.B.L., C.A.S.), Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892; Biostatistics and Clinical Epidemiology Service (N.S.), Clinical Center, National Institutes of Health, Bethesda, Maryland 20892; Laboratory of Pathology (M.M.Q., M.M.), Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892; Department of Pediatrics (A.H.), University Hospitals Case Medical Center, Rainbow Babies and Children's Hospital, Cleveland, Ohio 44106; Cardiovascular Disease Section (R.L., G.A., L.D., B.R.), Genomics of Metabolic, Cardiovascular, and Inflammatory Disease Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892; Department of Endocrinology, Metabolism, and Diabetes (A.D., S.Y.G., R.N., J.B.), Inserm Unit 1016, Centre National de la Recherche Scientifique UMR 8104, Institut Cochin, 75014 Paris, France; and Endocrine Oncology Branch (E.K.), National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.

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http://dx.doi.org/10.1210/jc.2014-4167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454793PMC
June 2015

Multi-omics analysis defines core genomic alterations in pheochromocytomas and paragangliomas.

Nat Commun 2015 Jan 27;6:6044. Epub 2015 Jan 27.

1] INSERM, UMR970, Paris-Cardiovascular Research Center, F-75015 Paris, France [2] Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, F-75006 Paris, France [3] Department of Genetics, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, F-75015 Paris, France [4] Rare Adrenal Cancer Network COMETE, F-75006 Paris, France.

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http://dx.doi.org/10.1038/ncomms7044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354166PMC
January 2015

Primary pigmented nodular adrenocortical disease: the original 4 cases revisited after 30 years for follow-up, new investigations, and molecular genetic findings.

Am J Surg Pathol 2014 Sep;38(9):1266-73

*Department of Laboratory Medicine and Pathology ‡Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN †Service d'Endocrinologie, Hôpital Cochin, Paris, France.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PAS.0000000000000220DOI Listing
September 2014

Macronodular adrenal hyperplasia due to mutations in an armadillo repeat containing 5 (ARMC5) gene: a clinical and genetic investigation.

J Clin Endocrinol Metab 2014 Jun 6;99(6):E1113-9. Epub 2014 Mar 6.

Section on Endocrinology and Genetics (F.R.F., M.Z., M.B.L., E.S., G.T., A.B., C.A.S.), Program on Developmental Endocrinology and Genetics, Program on Reproductive and Adult Endocrinology (M.Z.), Biostatistics and Clinical Epidemiology Service (N.S.), Clinical Center, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892; Group for Advanced Molecular Investigation (F.R.F.), Graduate Program in Health Science, Center for Biological and Sciences, Pontificia Universidade Catolica do Paraná, Curitiba Brazil 80215-901; Department of Endocrinology, Metabolism, and Cancer (R.L., G.A., S.E., L.D., B.R., J.B.), INSERM Unité 1016, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104, Institut Cochin, 75014 Paris, France.

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http://dx.doi.org/10.1210/jc.2013-4280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037724PMC
June 2014

A feminizing adrenocortical carcinoma in the context of a late onset 21-hydroxylase deficiency.

J Clin Endocrinol Metab 2014 Jun 21;99(6):1943-4. Epub 2014 Mar 21.

French COMETE Network (R.L.), 75014 Paris, France; Centre for Endocrinology, Diabetes and Metabolism, School of Clinical and Experimental Medicine (W.A.), University of Birmingham, Birmingham B15 2TT, United Kingdom; INSERM U982 (E.L.), Différenciation & Communication Neuronale & Neuroendocrine, Université de Rouen, 76821 Mont-Saint-Aignan, France; Departments of Endocrinology (C.W., L.G.), Hormonal Biology (J.G.), Pathology (M.S.), and Oncogenetics (E.C.), Hôpital Cochin, Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris, France; and INSERM U1016 (L.G.), Institut Cochin, 75014 Paris, France.

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http://dx.doi.org/10.1210/jc.2014-1342DOI Listing
June 2014

Integrated genomic characterization of adrenocortical carcinoma.

Nat Genet 2014 Jun 20;46(6):607-12. Epub 2014 Apr 20.

1] INSERM U1016, Institut Cochin, Paris, France. [2] CNRS UMR 8104, Paris, France. [3] Université Paris Descartes, Sorbonne Paris Cité, Paris, France. [4] Center for Rare Adrenal Diseases, Department of Endocrinology, Assistance Publique-Hôpitaux de Paris, Hôpital Cochin, Paris, France. [5] Rare Adrenal Cancer Network COMETE, Paris, France. [6].

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http://dx.doi.org/10.1038/ng.2953DOI Listing
June 2014

[Adrenocortical carcinoma: Update in 2014].

Presse Med 2014 Apr 7;43(4 Pt 1):401-9. Epub 2014 Mar 7.

Hôpital Cochin, service des maladies endocriniennes et métaboliques, centre de référence des cancers rares - COMETE-Cancer, 75014 Paris, France; Inserm U-1016, CNRS UMR8104, institut Cochin, université Paris-5, faculté de médecine Paris Descartes, 75006 Paris, France.

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http://dx.doi.org/10.1016/j.lpm.2014.01.009DOI Listing
April 2014

ARMC5 mutations in macronodular adrenal hyperplasia with Cushing's syndrome.

N Engl J Med 2013 Nov;369(22):2105-14

From INSERM Unité 1016, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104, Institut Cochin (G.A., R.L., S.E., M.R.-R., A.G., W.L., O.B., L.L., S.R., K.P., F.R.-C., F.L., L. Groussin, X.B., B.R., J.B.), Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité (G.A., S.E., A.G., O.B., L.L., M.S., K.P., F.R.-C., L. Groussin, X.B., J.B.), Department of Endocrinology, Referral Center for Rare Adrenal Diseases (G.A., R.L., O.B., L. Guignat, L. Groussin, X.B., J.B.), and Department of Pathology (M.S.), Assistance Publique-Hôpitaux de Paris, Hôpital Cochin, and Unit of Endocrinology, Department of Obstetrics and Gynecology, Hôpital Tenon (N.C.-B.) - all in Paris; Unit of Endocrinology, Centre Hospitalier du Centre Bretagne, Site de Kério, Noyal-Pontivy (B.T.), Unit of Endocrinology, Hôtel Dieu du Creusot, Le Creusot (A.P.), and Department of Endocrinology Lyon-Est, Groupement Hospitalier Est, Bron (F.B.-C.) - all in France; and the Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics and the Pediatric Endocrinology Inter-Institute Training Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD (C.A.S.).

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http://dx.doi.org/10.1056/NEJMoa1304603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727443PMC
November 2013

Intraadrenal corticotropin in bilateral macronodular adrenal hyperplasia.

N Engl J Med 2013 Nov;369(22):2115-25

From INSERM Unité 982, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication, Institute for Research and Innovation in Biomedicine, and Rouen University, Mont-Saint-Aignan (E.L., C.D., S.R., M.T.N., I.B., Z.B., J-.M.K., Y.A., H.L.), the Department of Endocrinology, Hôpital Bicêtre, Assistance Publique-Hôpitaux de Paris (AP-HP), University Paris Sud, INSERM Unité 693, Le Kremlin-Bicêtre (J.Y.), INSERM Unité 1016, Institut Cochin (R.L., L.G., X.B., J.B.), the Department of Endocrinology AP-HP, Hôpital Cochin (L.G., X.B., J.B.), Université Paris Descartes (L.G., X.B., J.B.), Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104 (L.G., X.B., J.B.), and the Department of Endocrinology, Hôpital Saint-Antoine, AP-HP (S.C.-M.), Paris; the Department of Endocrinology and Metabolic Diseases, Centre Hospitalier Universitaire Larrey, Toulouse (P.C.); the Department of Endocrinology, Hôpital Haut Lévêque, Centre Hospitalier Universitaire de Bordeaux, Pessac (A.T.); Service de Médecine Interne et Nutrition, Centre Hospitalier Régional Universitaire de Strasbourg, Strasbourg (F.G.); and the Department of Endocrinology, Diabetes, and Metabolic Diseases, Rouen University Hospital, Rouen (J.M.K., H.L.) - all in France.

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http://dx.doi.org/10.1056/NEJMoa1215245DOI Listing
November 2013

A rare cause of hypertestosteronemia in a 68-year-old patient: a Leydig cell tumor due to a somatic GNAS (guanine nucleotide-binding protein, alpha-stimulating activity polypeptide 1)-activating mutation.

J Androl 2012 Jul-Aug;33(4):578-84. Epub 2011 Oct 20.

Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 1016, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104, Department of Endocrinology, Metabolism and Cancer, Institut Cochin, Paris, France.

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http://dx.doi.org/10.2164/jandrol.111.013441DOI Listing
November 2012

Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP-specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours.

Clin Endocrinol (Oxf) 2012 Aug;77(2):195-9

Section on Endocrinology and Genetics and Pediatric Endocrinology Training Program, both at Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1103, USA.

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http://dx.doi.org/10.1111/j.1365-2265.2012.04366.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360985PMC
August 2012

Epithelial to mesenchymal transition is activated in metastatic pheochromocytomas and paragangliomas caused by SDHB gene mutations.

J Clin Endocrinol Metab 2012 Jun 4;97(6):E954-62. Epub 2012 Apr 4.

Centre de recherche cardiovasculaire de l'Hôpital Européen Georges Pompidou, 56 rue Leblanc 75015 Paris, France.

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http://dx.doi.org/10.1210/jc.2011-3437DOI Listing
June 2012

Pasireotide in Cushing's disease.

N Engl J Med 2012 05;366(22):2134; author reply 2134-5

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http://dx.doi.org/10.1056/NEJMc1204078DOI Listing
May 2012

The Weiss score and beyond--histopathology for adrenocortical carcinoma.

Horm Cancer 2011 Dec;2(6):333-40

Department of Clinical and Biological Sciences, University of Turin at San Luigi Hospital, regione Gonzole 10, 10043, Orbassano, Turin, Italy.

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http://dx.doi.org/10.1007/s12672-011-0088-0DOI Listing
December 2011

Adrenocortical carcinoma: a clinician's update.

Nat Rev Endocrinol 2011 Jun 8;7(6):323-35. Epub 2011 Mar 8.

Department of Internal Medicine I, Endocrine Unit, University Hospital, University of Würzburg, Oberdürrbacher Straße 6, 97080 Würzburg, Germany.

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http://dx.doi.org/10.1038/nrendo.2010.235DOI Listing
June 2011

Phosphodiesterase 11A (PDE11A) genetic variants may increase susceptibility to prostatic cancer.

J Clin Endocrinol Metab 2011 Jan 29;96(1):E135-40. Epub 2010 Sep 29.

Section of Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1210/jc.2010-1655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3038491PMC
January 2011

SDHA is a tumor suppressor gene causing paraganglioma.

Hum Mol Genet 2010 Aug 18;19(15):3011-20. Epub 2010 May 18.

Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Génétique, 20-40 rue Leblanc, F-75015 Paris, France.

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http://dx.doi.org/10.1093/hmg/ddq206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901140PMC
August 2010

Aberrant cortisol regulations in bilateral macronodular adrenal hyperplasia: a frequent finding in a prospective study of 32 patients with overt or subclinical Cushing's syndrome.

Eur J Endocrinol 2010 Jul 8;163(1):129-38. Epub 2010 Apr 8.

Department of Endocrinology, Metabolism and Cancer, Institut National de la Santé et de la Recherche Médicale Unité 567, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104, Institut Cochin, 75014 Paris, France.

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http://dx.doi.org/10.1530/EJE-10-0195DOI Listing
July 2010

ACTH-independent Cushing's syndrome with bilateral micronodular adrenal hyperplasia and ectopic adrenocortical adenoma.

J Clin Endocrinol Metab 2010 Jan 13;95(1):18-24. Epub 2009 Nov 13.

Institut National de la Santé et de la Recherche Médicale, Unité 982/Equipe Associée 4310, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication, Institut Fédératif de Recherches Multidisciplinaires sur les Peptides 23, University of Rouen, 76821 Mont-Saint-Aignan, France.

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http://dx.doi.org/10.1210/jc.2009-0881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805485PMC
January 2010

Adrenocortical tumor with two distinct elements revealed by combined (18)F-fluorodeoxyglucose positron emission tomography and (131)I nor-cholesterol scintigraphy.

J Clin Endocrinol Metab 2009 Oct;94(10):3631-2

Institut National de la Santé et de la Recherche Mé diale Unité 567, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104, Department of Endocrinology, Metabolism and Cancer, 75014 Paris, France.

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http://dx.doi.org/10.1210/jc.2009-1025DOI Listing
October 2009

The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on protein kinase A catalytic subunits.

J Clin Endocrinol Metab 2009 Jul 21;94(7):2406-13. Epub 2009 Apr 21.

Institut National de la Santé et de la Recherche Médicale, Unité 413, EA4310, Laboratory of Differentiation and Neuronal and Neuroendocrine Communication, University of Rouen, Mont Saint Aignan, France.

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http://dx.doi.org/10.1210/jc.2009-0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708955PMC
July 2009

Functional phosphodiesterase 11A mutations may modify the risk of familial and bilateral testicular germ cell tumors.

Cancer Res 2009 Jul 23;69(13):5301-6. Epub 2009 Jun 23.

Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 10 Center Drive, CRC, Room 1-3330, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-0884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734464PMC
July 2009

A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex.

Eur J Hum Genet 2008 Oct 23;16(10):1245-53. Epub 2008 Apr 23.

Section on Endocrinology & Genetics, Program on Developmental Endocrinology & Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/ejhg.2008.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671148PMC
October 2008

[Adrenal cortical carcinoma: advances in the pathophysiology and management of this malignancy].

Bull Acad Natl Med 2008 Jan;192(1):87-102; discussion 102-3

Service des Maladies Endocriniennes et Métaboliques, Hôpital Cochin, Paris, Faculté de médecine Paris-Descartes, Université Paris 5.

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January 2008

Adrenocortical cancer: pathophysiology and clinical management.

Endocr Relat Cancer 2007 Mar;14(1):13-28

INSERM U567, Endocrinology, Metabolism and Cancer Department, Institut Cochin, Paris, France.

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https://erc.bioscientifica.com/view/journals/erc/14/1/014001
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http://dx.doi.org/10.1677/erc.1.01130DOI Listing
March 2007

Somatic TP53 mutations are relatively rare among adrenocortical cancers with the frequent 17p13 loss of heterozygosity.

Clin Cancer Res 2007 Feb;13(3):844-50

Institut National de la Sante et de la Recherche Medicale U567, Centre National de la Recherche Scientifique UMR8104, Université Paris 5, and Assitance Publique-Hôpitaux de Paris, France.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-06-2085DOI Listing
February 2007

Molecular genetics of adrenocortical tumours, from familial to sporadic diseases.

Eur J Endocrinol 2005 Oct;153(4):477-87

INSERM U567 and CNRS UMR 8104, Institut Cochin, Paris, France.

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http://dx.doi.org/10.1530/eje.1.02004DOI Listing
October 2005

Ghrelin and adiponectin in patients with Cushing's disease before and after successful transsphenoidal surgery.

Clin Endocrinol (Oxf) 2005 Jan;62(1):30-6

Institute of Endocrine Science, University of Milan, Ospedale Maggiore IRCCS, Milan, Italy.

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http://dx.doi.org/10.1111/j.1365-2265.2004.02169.xDOI Listing
January 2005

Effect of recombinant human growth hormone (GH) replacement on the hypothalamic-pituitary-adrenal axis in adult GH-deficient patients.

J Clin Endocrinol Metab 2004 Nov;89(11):5397-401

Institute of Endocrine Sciences, University of Milan, Ospedale Maggiore IRCCS, Pad. Granelli, Via F. Sforza, 35, 20122 Milan, Italy.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2004-1114DOI Listing
November 2004

Effects of chronic administration of PPAR-gamma ligand rosiglitazone in Cushing's disease.

Eur J Endocrinol 2004 Aug;151(2):173-8

Endocrinology Unit, Department of Medical and Surgical Sciences, University of Milan, Istituto Policlinico San Donato, San Donato Milanese, Milan, Italy.

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http://dx.doi.org/10.1530/eje.0.1510173DOI Listing
August 2004

Coexistence of 21-hydroxylase and 11 beta-hydroxylase deficiency in adrenal incidentalomas and in subclinical Cushing's syndrome.

Horm Res 2002 ;57(5-6):192-6

Institute of Endocrine Sciences, Ospedale Maggiore IRCCS, Milan, Italy.

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http://dx.doi.org/10.1159/000058381DOI Listing
October 2002

Long-term follow-up study of patients with adrenal incidentalomas.

Eur J Endocrinol 2002 Oct;147(4):489-94

Institute of Endocrine Sciences, University of Milan, Ospedale Maggiore IRCCS, Milan, Italy.

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http://dx.doi.org/10.1530/eje.0.1470489DOI Listing
October 2002