Ross McManus

Ross McManus

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Ross McManus

Ross McManus

Publications by authors named "Ross McManus"

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Changes in Presentation of Celiac Disease in Ireland From the 1960s to 2015.

Clin Gastroenterol Hepatol 2017 Jun 31;15(6):864-871.e3. Epub 2016 Dec 31.

Trinity Translational Medicine Institute & Department of Clinical Medicine, Trinity Centre for Health Science, St James's Hospital, Dublin, Republic of Ireland.

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http://dx.doi.org/10.1016/j.cgh.2016.11.018DOI Listing
June 2017

Viral Bronchiolitis is Associated With Altered Cytokine Gene Expression and Lymphocyte Activation Status.

Pediatr Infect Dis J 2016 11;35(11):e326-e338

From the *Department of Paediatrics, Children's University Hospital, Temple Street, Dublin 1, Ireland; †Department of Clinical Medicine, ‡Department of Immunology, Trinity College, Dublin, Ireland; §Department of Anaesthesia and Critical Care Medicine, St. James' Hospital, James's St, Dublin 8, Ireland; and ¶National Virus Reference Laboratory, University College Dublin, Dublin 4, Ireland.

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http://dx.doi.org/10.1097/INF.0000000000001299DOI Listing
November 2016

Cloning Gene Variants and Reporter Assays.

Methods Mol Biol 2015 ;1326:117-30

Department of Medicine, Institute of Molecular Medicine, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1007/978-1-4939-2839-2_12DOI Listing
August 2016

Candidate Gene Knockdown in Celiac Disease.

Methods Mol Biol 2015 ;1326:159-73

Department of Medicine, Institute of Molecular Medicine, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1007/978-1-4939-2839-2_14DOI Listing
August 2016

Quality Control Procedures for High-Throughput Genetic Association Studies.

Methods Mol Biol 2015 ;1326:203-15

Department of Medicine, Institute of Molecular Medicine, Trinity College Dublin, College Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1007/978-1-4939-2839-2_17DOI Listing
August 2016

Quality Control and Analysis of NGS RNA Sequencing Data.

Methods Mol Biol 2015 ;1326:217-32

Department of Medicine, Institute of Molecular Medicine, Trinity College Dublin, College Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1007/978-1-4939-2839-2_18DOI Listing
August 2016

Replication of a distinct psoriatic arthritis risk variant at the IL23R locus.

Ann Rheum Dis 2016 07 25;75(7):1417-8. Epub 2016 Mar 25.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, The University of Manchester, UK NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academy of Health Sciences, Manchester, UK The Kellgren Centre for Rheumatology, Central Manchester Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2016-209290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941176PMC
July 2016

Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity.

J Allergy Clin Immunol 2016 Feb 20;137(2):482-91. Epub 2015 Aug 20.

Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland; Institute of Molecular Medicine, St James's Hospital, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735016PMC
February 2016

PTPN22 is associated with susceptibility to psoriatic arthritis but not psoriasis: evidence for a further PsA-specific risk locus.

Ann Rheum Dis 2015 Oct 28;74(10):1882-5. Epub 2015 Apr 28.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute for Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK The Kellgren Centre for Rheumatology, Central Manchester Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2014-207187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602265PMC
October 2015

Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus.

Gastroenterology 2015 Feb 5;148(2):367-78. Epub 2014 Nov 5.

University Hospitals Coventry & Warwickshire NHS Trust, Warwickshire, England; Warwick Medical School, University of Warwick, Warwickshire, England. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.10.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315134PMC
February 2015

Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.

Nat Commun 2015 Feb 5;6:6046. Epub 2015 Feb 5.

1] Arthritis Research UK Centre for Genetics and Genomics, The University of Manchester, Manchester M13 9PT, UK [2] NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academy of Health Sciences, Manchester M13 9WU, UK.

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http://dx.doi.org/10.1038/ncomms7046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327416PMC
February 2015

Characterising cytokine gene expression signatures in patients with severe sepsis.

Mediators Inflamm 2013 2;2013:164246. Epub 2013 Jul 2.

Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1155/2013/164246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713593PMC
February 2014

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.

Authors:
Zhan Su Laura J Gay Amy Strange Claire Palles Gavin Band David C Whiteman Francesco Lescai Cordelia Langford Manoj Nanji Sarah Edkins Anouk van der Winkel David Levine Peter Sasieni Céline Bellenguez Kimberley Howarth Colin Freeman Nigel Trudgill Art T Tucker Matti Pirinen Maikel P Peppelenbosch Luc J W van der Laan Ernst J Kuipers Joost P H Drenth Wilbert H Peters John V Reynolds Dermot P Kelleher Ross McManus Heike Grabsch Hans Prenen Raf Bisschops Kausila Krishnadath Peter D Siersema Jantine W P M van Baal Mark Middleton Russell Petty Richard Gillies Nicola Burch Pradeep Bhandari Stuart Paterson Cathryn Edwards Ian Penman Kishor Vaidya Yeng Ang Iain Murray Praful Patel Weimin Ye Paul Mullins Anna H Wu Nigel C Bird Helen Dallal Nicholas J Shaheen Liam J Murray Konrad Koss Leslie Bernstein Yvonne Romero Laura J Hardie Rui Zhang Helen Winter Douglas A Corley Simon Panter Harvey A Risch Brian J Reid Ian Sargeant Marilie D Gammon Howard Smart Anjan Dhar Hugh McMurtry Haythem Ali Geoffrey Liu Alan G Casson Wong-Ho Chow Matt Rutter Ashref Tawil Danielle Morris Chuka Nwokolo Peter Isaacs Colin Rodgers Krish Ragunath Chris MacDonald Chris Haigh David Monk Gareth Davies Saj Wajed David Johnston Michael Gibbons Sue Cullen Nicholas Church Ruth Langley Michael Griffin Derek Alderson Panos Deloukas Sarah E Hunt Emma Gray Serge Dronov Simon C Potter Avazeh Tashakkori-Ghanbaria Mark Anderson Claire Brooks Jenefer M Blackwell Elvira Bramon Matthew A Brown Juan P Casas Aiden Corvin Audrey Duncanson Hugh S Markus Christopher G Mathew Colin N A Palmer Robert Plomin Anna Rautanen Stephen J Sawcer Richard C Trembath Ananth C Viswanathan Nicholas Wood Gosia Trynka Cisca Wijmenga Jean-Baptiste Cazier Paul Atherfold Anna M Nicholson Nichola L Gellatly Deborah Glancy Sheldon C Cooper David Cunningham Tore Lind Julie Hapeshi David Ferry Barrie Rathbone Julia Brown Sharon Love Stephen Attwood Stuart MacGregor Peter Watson Scott Sanders Weronica Ek Rebecca F Harrison Paul Moayyedi John de Caestecker Hugh Barr Elia Stupka Thomas L Vaughan Leena Peltonen Chris C A Spencer Ian Tomlinson Peter Donnelly Janusz A Z Jankowski

Nat Genet 2012 Oct 9;44(10):1131-6. Epub 2012 Sep 9.

Wellcome Trust Centre for Human Genetics, Oxford, UK.

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http://dx.doi.org/10.1038/ng.2408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459818PMC
October 2012

An update on female sexual function and dysfunction in old age and its relevance to old age psychiatry.

Aging Dis 2012 Oct 25;3(5):373-84. Epub 2012 Aug 25.

Old Age Psychiatry, Sheffield Health and Social Care Trust, Eastglade Centre, Sheffield, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501393PMC
October 2012

Genes of the interleukin-18 pathway are associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma.

Am J Gastroenterol 2012 Sep 5;107(9):1331-41. Epub 2012 Jun 5.

Department of Surgery, St. James's Hospital and Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1038/ajg.2012.134DOI Listing
September 2012

High dietary saturated fat intake accentuates obesity risk associated with the fat mass and obesity-associated gene in adults.

J Nutr 2012 May 28;142(5):824-31. Epub 2012 Mar 28.

Nutrigenomics Research Group, University College Dublin School of Public Health and Population Science, University College Dublin Conway Institute, Dublin, Ireland.

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http://dx.doi.org/10.3945/jn.111.153460DOI Listing
May 2012

Dietary saturated fat, gender and genetic variation at the TCF7L2 locus predict the development of metabolic syndrome.

J Nutr Biochem 2012 Mar 2;23(3):239-44. Epub 2011 May 2.

Nutrigenomics Research Group, UCD School of Public Health and Population Science, UCD Conway Institute, University College Dublin, Ireland.

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http://dx.doi.org/10.1016/j.jnutbio.2010.11.020DOI Listing
March 2012

Dietary fat, abdominal obesity and smoking modulate the relationship between plasma complement component 3 concentrations and metabolic syndrome risk.

Atherosclerosis 2012 Feb 16;220(2):513-9. Epub 2011 Nov 16.

Nutrigenomics Research Group, UCD Conway Institute, UCD School of Public Health and Population Science, University College Dublin, Belfield, Dublin 4, Ireland.

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http://linkinghub.elsevier.com/retrieve/pii/S002191501101076
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http://dx.doi.org/10.1016/j.atherosclerosis.2011.11.007DOI Listing
February 2012

Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis.

Ann Rheum Dis 2011 Sep 29;70(9):1641-4. Epub 2011 May 29.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/ard.2011.150102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147229PMC
September 2011

Common variation in the vitamin D receptor gene and risk of inflammatory bowel disease in an Irish case-control study.

Eur J Gastroenterol Hepatol 2011 Sep;23(9):807-12

Department of Clinical Medicine, Adelaide and Meath Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1097/MEG.0b013e328349283eDOI Listing
September 2011

The myeloid transcription factor KLF2 regulates the host response to polymicrobial infection and endotoxic shock.

Immunity 2011 May 12;34(5):715-28. Epub 2011 May 12.

Case Cardiovascular Research Institute, Department of Medicine, Harrington-McLaughlin Heart and Vascular Institute, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1016/j.immuni.2011.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103656PMC
May 2011

Hospital-acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expression.

Chest 2011 Mar 9;139(3):626-632. Epub 2010 Sep 9.

Department of Anaesthesia and Intensive Care Medicine, St James Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1378/chest.10-0016DOI Listing
March 2011

Gene-nutrient interactions and gender may modulate the association between ApoA1 and ApoB gene polymorphisms and metabolic syndrome risk.

Atherosclerosis 2011 Feb 3;214(2):408-14. Epub 2010 Nov 3.

Nutrigenomics Research Group, UCD Conway Institute, UCD School of Public Health and Population Science, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2010.10.029DOI Listing
February 2011

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

Nat Genet 2010 Nov 17;42(11):985-90. Epub 2010 Oct 17.

Wellcome Trust Centre for Human Genetics, Oxford, UK.

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http://dx.doi.org/10.1038/ng.694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749730PMC
November 2010

Transforming growth factor beta-1 and interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection.

Cytokine 2010 Jun 5;50(3):322-7. Epub 2010 Mar 5.

Department of Anaesthesia, St. James Hospital, Dublin 8, Ireland; Institute of Molecular Medicine, Trinity College Dublin, Ireland.

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http://dx.doi.org/10.1016/j.cyto.2010.01.003DOI Listing
June 2010

Multiple common variants for celiac disease influencing immune gene expression.

Nat Genet 2010 Apr 28;42(4):295-302. Epub 2010 Feb 28.

Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1038/ng.543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847618PMC
April 2010

Additive effect of polymorphisms in the IL-6, LTA, and TNF-{alpha} genes and plasma fatty acid level modulate risk for the metabolic syndrome and its components.

J Clin Endocrinol Metab 2010 Mar 15;95(3):1386-94. Epub 2010 Jan 15.

Nutrigenomics Research Group, University College Dublin School of Public Health and Population Science, University College Dublin Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2009-1081DOI Listing
March 2010

Complement component 3 polymorphisms interact with polyunsaturated fatty acids to modulate risk of metabolic syndrome.

Am J Clin Nutr 2009 Dec 14;90(6):1665-73. Epub 2009 Oct 14.

Nutrigenomics Research Group, UCD School of Public Health and Population Science, UCD Conway Institute, University College Dublin, Dublin, Ireland.

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https://academic.oup.com/ajcn/article/90/6/1665/4598129
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http://dx.doi.org/10.3945/ajcn.2009.28101DOI Listing
December 2009

Dietary saturated fat modulates the association between STAT3 polymorphisms and abdominal obesity in adults.

J Nutr 2009 Nov 23;139(11):2011-7. Epub 2009 Sep 23.

Nutrigenomics Research Group, School of Public Health and Population Science, University College Dublin Conway Institute, University College, Dublin 4, Ireland.

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https://academic.oup.com/jn/article/139/11/2011/4751038
Publisher Site
http://dx.doi.org/10.3945/jn.109.110635DOI Listing
November 2009

Analysis of HLA and non-HLA alleles can identify individuals at high risk for celiac disease.

Gastroenterology 2009 Sep 18;137(3):834-40, 840.e1-3. Epub 2009 May 18.

Department of Genetics, University Medical Centre of Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1053/j.gastro.2009.05.040DOI Listing
September 2009

Association of gastric disease with polymorphisms in the inflammatory-related genes IL-1B, IL-1RN, IL-10, TNF and TLR4.

Eur J Gastroenterol Hepatol 2009 Jun;21(6):630-5

Cancer Prevention Fellowship Program, Office of Preventive Oncology and Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1097/MEG.0b013e3283140eeaDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802816PMC
June 2009

NF-kappaB regulation: the nuclear response.

J Cell Mol Med 2009 Apr;13(4):631-43

Department of Clinical Medicine and Institute of Molecular Medicine, Trinity College, Dublin, Ireland.

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http://dx.doi.org/10.1111/j.1582-4934.2009.00632.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822870PMC
April 2009

Natural selection and the molecular basis of electrophoretic variation at the coagulation F13B locus.

Eur J Hum Genet 2009 Feb 20;17(2):219-27. Epub 2008 Aug 20.

Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

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http://dx.doi.org/10.1038/ejhg.2008.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2986062PMC
February 2009

Shared and distinct genetic variants in type 1 diabetes and celiac disease.

N Engl J Med 2008 Dec 10;359(26):2767-77. Epub 2008 Dec 10.

Juvenile Diabetes Research Foundation-Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://www.nejm.org/doi/abs/10.1056/NEJMoa0807917
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http://dx.doi.org/10.1056/NEJMoa0807917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840835PMC
December 2008

The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expression.

Intensive Care Med 2008 Apr 29;34(4):683-91. Epub 2008 Jan 29.

Department of Anaesthesia, St James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1007/s00134-007-0968-5DOI Listing
April 2008

Filaggrin null alleles are not associated with psoriasis.

J Invest Dermatol 2007 Aug 5;127(8):1878-82. Epub 2007 Apr 5.

Epithelial Genetics Group, Human Genetics Unit, Division of Pathology and Neuroscience, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.

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http://dx.doi.org/10.1038/sj.jid.5700817DOI Listing
August 2007

Genetic polymorphisms and the risk of infection following esophagectomy. positive association with TNF-alpha gene -308 genotype.

Ann Surg 2007 Jul;246(1):122-8

Department of Clinical Surgery and Dublin, of Molecular Medicine Center, St. Jame's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1097/01.sla.0000259389.09161.49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899211PMC
July 2007

Coagulopathy after cardiac surgery may be influenced by a functional plasminogen activator inhibitor polymorphism.

Anesth Analg 2007 Jun;104(6):1343-7, table of contents

Department of Anaesthesia, Trinity Centre for Health Sciences, St. James's Hospital, Dublin, Ireland.

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https://insights.ovid.com/crossref?an=00000539-200706000-000
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http://dx.doi.org/10.1213/01.ane.0000261267.28891.00DOI Listing
June 2007

Gene polymorphism and requirement for vasopressor infusion after cardiac surgery.

Ann Thorac Surg 2006 Sep;82(3):895-901

Department of Cardiothoracic Surgery, St. James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.athoracsur.2006.04.029DOI Listing
September 2006

Genetic and nutrient determinants of the metabolic syndrome.

Curr Opin Cardiol 2006 May;21(3):185-93

Nutrigenomics Research Group, Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin, Ireland.

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http://pdfs.journals.lww.com/co-cardiology/2006/05000/Geneti
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Publisher Site
http://dx.doi.org/10.1097/01.hco.0000221579.25878.11DOI Listing
May 2006

Pharmacogenetics of inflammatory bowel disease.

Novartis Found Symp 2004 ;263:41-53; discussion 53-6, 211-8

Department of Clinical Medicine and Dublin Molecular Medicine Centre, Trinity College Dublin, Ireland.

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February 2005

Haplotype frequency estimation error analysis in the presence of missing genotype data.

BMC Bioinformatics 2004 Dec 1;5:188. Epub 2004 Dec 1.

Hitachi Dublin Lab,, Hitachi Europe Ltd., O'Reilly Institute, Trinity College, Dublin 2, Ireland.

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http://dx.doi.org/10.1186/1471-2105-5-188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544188PMC
December 2004

Mechanisms of steroid action and resistance in inflammation and disease.

Authors:
Ross McManus

J Endocrinol 2003 Jul;178(1):1-4

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http://dx.doi.org/10.1677/joe.0.1780001DOI Listing
July 2003

Celiac disease--the villain unmasked?

N Engl J Med 2003 Jun;348(25):2573-4

Dublin Molecular Medicine Centre, Trinity Centre for Health Sciences, St. James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1056/NEJMcibr035033DOI Listing
June 2003