Publications by authors named "Ross D Hannan"

94Publications

Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression.

Cancer Res 2020 Sep 10;80(17):3706-3718. Epub 2020 Jul 10.

Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-3914DOI Listing
September 2020

Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes.

Mol Cell 2020 08 25;79(4):546-560.e7. Epub 2020 Jun 25.

Laboratory of Regulation of Gene Expression, Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, 142 20, Prague, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2020.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447980PMC
August 2020

Transcriptional repression of Myc underlies the tumour suppressor function of AGO1 in .

Development 2020 Jun 11;147(11). Epub 2020 Jun 11.

Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia

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http://dx.doi.org/10.1242/dev.190231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295588PMC
June 2020

Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age.

Cells 2020 01 21;9(2). Epub 2020 Jan 21.

ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, Australian National University, Acton 2601, Australian Capital Territory, Australia.

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http://dx.doi.org/10.3390/cells9020266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072222PMC
January 2020

Migration of Small Ribosomal Subunits on the 5' Untranslated Regions of Capped Messenger RNA.

Int J Mol Sci 2019 Sep 10;20(18). Epub 2019 Sep 10.

EMBL-Australia Collaborating Group, Department of Genome Sciences, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.

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http://dx.doi.org/10.3390/ijms20184464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769788PMC
September 2019

High-Content Imaging Approaches to Quantitate Stress-Induced Changes in Nucleolar Morphology.

Assay Drug Dev Technol 2018 Aug/Sep;16(6):320-332

1 ANU Centre for Therapeutic Discovery, The Australian National University , Acton, Australia .

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https://www.liebertpub.com/doi/10.1089/adt.2018.861
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http://dx.doi.org/10.1089/adt.2018.861DOI Listing
October 2019

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy.

Eur Urol 2018 11 23;74(5):562-572. Epub 2018 Jul 23.

Monash Partners Comprehensive Cancer Consortium, Monash Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia; Melbourne Urological Research Alliance (MURAL), Melbourne, VIC, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2018.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351078PMC
November 2018

Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers.

Proc Natl Acad Sci U S A 2018 05 18;115(18):4737-4742. Epub 2018 Apr 18.

Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia;

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http://dx.doi.org/10.1073/pnas.1720391115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939086PMC
May 2018

Transcriptional profiles for distinct aggregation states of mutant Huntingtin exon 1 protein unmask new Huntington's disease pathways.

Mol Cell Neurosci 2017 09 23;83:103-112. Epub 2017 Jul 23.

Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.mcn.2017.07.004DOI Listing
September 2017

Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis.

PLoS Negl Trop Dis 2017 03 6;11(3):e0005432. Epub 2017 Mar 6.

Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pntd.0005432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354456PMC
March 2017

Therapeutic Approaches Targeting MYC-Driven Prostate Cancer.

Genes (Basel) 2017 Feb 16;8(2). Epub 2017 Feb 16.

Prostate Cancer Translational Research Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.

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http://dx.doi.org/10.3390/genes8020071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333060PMC
February 2017

The Potential of Targeting Ribosome Biogenesis in High-Grade Serous Ovarian Cancer.

Int J Mol Sci 2017 Jan 20;18(1). Epub 2017 Jan 20.

Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.

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http://www.mdpi.com/1422-0067/18/1/210
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http://dx.doi.org/10.3390/ijms18010210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297839PMC
January 2017

Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription.

Gene 2017 May 15;612:36-48. Epub 2016 Dec 15.

Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia; The Department of Pathology, The University of Melbourne, Victoria 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2016.12.015DOI Listing
May 2017

The Dual Inhibition of RNA Pol I Transcription and PIM Kinase as a New Therapeutic Approach to Treat Advanced Prostate Cancer.

Clin Cancer Res 2016 Nov 2;22(22):5539-5552. Epub 2016 Aug 2.

Cancer Program, Biomedicine Discovery Institute and Department of Anatomy & Developmental Biology, Monash University, Victoria, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0124DOI Listing
November 2016

Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription.

Oncotarget 2016 Aug;7(31):48887-48904

Oncogenic Signaling and Growth Control Program, Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.18632/oncotarget.10346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226478PMC
August 2016

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma.

Cancer Discov 2016 Jan 21;6(1):59-70. Epub 2015 Oct 21.

Division of Research, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia. Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia. Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria, Australia. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1158/2159-8290.CD-14-0673DOI Listing
January 2016

Genome wide mapping of UBF binding-sites in mouse and human cell lines.

Genom Data 2015 Mar 5;3:103-5. Epub 2015 Jan 5.

Division of Cancer Research, Peter MacCallum Cancer Centre, St. Andrews Place, East Melbourne, Victoria 3002, Australia ; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3010, Australia ; Department of Pathology, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/j.gdata.2014.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535872PMC
March 2015

S6 Kinase is essential for MYC-dependent rDNA transcription in Drosophila.

Cell Signal 2015 Oct 26;27(10):2045-53. Epub 2015 Jul 26.

Department of Anatomy and Neuroscience, The University of Melbourne, Parkville 3010, Melbourne Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2015.07.018DOI Listing
October 2015

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models.

Nat Commun 2015 Jun 15;6:7404. Epub 2015 Jun 15.

Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Melbourne 3010, Australia.

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http://dx.doi.org/10.1038/ncomms8404DOI Listing
June 2015

Unexpected role of CDK4 in a G2/M checkpoint.

Cell Cycle 2015 ;14(9):1351-2

a Division of Cancer Research; Peter MacCallum Cancer Centre ; East Melbourne , Victoria , Australia.

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https://www.tandfonline.com/doi/full/10.1080/15384101.2015.1
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http://dx.doi.org/10.1080/15384101.2015.1022060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614524PMC
January 2016

Implications of epithelial-mesenchymal plasticity for heterogeneity in colorectal cancer.

Front Oncol 2015 2;5:13. Epub 2015 Feb 2.

Research Division, Peter MacCallum Cancer Centre , Melbourne, VIC , Australia ; Sir Peter MacCallum Department of Oncology, The University of Melbourne , Melbourne, VIC , Australia ; Department of Pathology, The University of Melbourne , Melbourne, VIC , Australia.

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http://dx.doi.org/10.3389/fonc.2015.00013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313606PMC
February 2015

The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy.

Biochim Biophys Acta 2015 Jul 11;1849(7):821-9. Epub 2014 Nov 11.

Division of Research, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3052, Australia; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3052, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3168, Australia; School of Biomedical Sciences, University of Queensland, Queensland 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2014.10.007DOI Listing
July 2015

A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes.

Genome Res 2015 Feb 1;25(2):201-12. Epub 2014 Dec 1.

Research Division, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3010, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia; Division of Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia; School of Biomedical Sciences, University of Queensland, Brisbane 4072, Queensland, Australia

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http://dx.doi.org/10.1101/gr.176115.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315294PMC
February 2015

Regulation of rDNA transcription in response to growth factors, nutrients and energy.

Gene 2015 Feb 8;556(1):27-34. Epub 2014 Nov 8.

Division of Research, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia.

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http://dx.doi.org/10.1016/j.gene.2014.11.010DOI Listing
February 2015

Widespread FRA1-dependent control of mesenchymal transdifferentiation programs in colorectal cancer cells.

PLoS One 2014 21;9(3):e88950. Epub 2014 Mar 21.

Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Victoria, Australia; Department of Pathology, University of Melbourne, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088950PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962334PMC
January 2015

Targeting the nucleolus for cancer intervention.

Biochim Biophys Acta 2014 Jun 2;1842(6):802-16. Epub 2014 Jan 2.

Oncogenic Signalling and Growth Control Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia; Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia; Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia; School of Biomedical Sciences, The University of Queensland, St Lucia, Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2013.12.009DOI Listing
June 2014

Perturbations at the ribosomal genes loci are at the centre of cellular dysfunction and human disease.

Cell Biosci 2014 19;4:43. Epub 2014 Aug 19.

Growth Control Laboratory, Research Division, Peter MacCallum Cancer Centre, St. Andrews Place, East Melbourne, Victoria 3002, Australia ; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3010, Australia ; Department of Pathology, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1186/2045-3701-4-43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422213PMC
May 2015

A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation.

J Cell Sci 2013 Dec 17;126(Pt 23):5377-90. Epub 2013 Sep 17.

School of Biomedical Sciences, The University of Queensland, St. Lucia, Queensland, 4072, Australia.

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http://dx.doi.org/10.1242/jcs.128280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843137PMC
December 2013

Synergistic inhibition of ovarian cancer cell growth by combining selective PI3K/mTOR and RAS/ERK pathway inhibitors.

Eur J Cancer 2013 Dec 3;49(18):3936-44. Epub 2013 Sep 3.

Oncogenic Signalling and Growth Control Program, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett St, Melbourne, Victoria 8006, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3010, Australia; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/j.ejca.2013.08.007DOI Listing
December 2013

AKT-independent PI3-K signaling in cancer - emerging role for SGK3.

Cancer Manag Res 2013 26;5:281-92. Epub 2013 Aug 26.

Division of Cancer Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia ; School of Biological Sciences, Flinders University, Bedford Park, South Australia, Australia.

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http://dx.doi.org/10.2147/CMAR.S35178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762672PMC
September 2013

Targeting the nucleolus for cancer-specific activation of p53.

Drug Discov Today 2014 Mar 28;19(3):259-65. Epub 2013 Aug 28.

The Translational Genomics Research Institute, 445 N. Fifth Street, Phoenix, AZ 85004, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2013.08.012DOI Listing
March 2014

Unravelling the molecular complexity of GPCR-mediated EGFR transactivation using functional genomics approaches.

FEBS J 2013 Nov 23;280(21):5258-68. Epub 2013 Sep 23.

School of Biomedical Sciences, The University of Queensland, St Lucia, Qld, Australia; Oncogenic Signalling and Growth Control Program, Peter MacCallum Cancer Centre, East Melbourne, Vic., Australia; Department of Pathology, The University of Melbourne, Parkville, Vic., Australia.

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http://dx.doi.org/10.1111/febs.12509DOI Listing
November 2013

The nucleolus: an emerging target for cancer therapy.

Trends Mol Med 2013 Nov 15;19(11):643-54. Epub 2013 Aug 15.

Division of Cancer Research, Peter MacCallum Cancer Centre, East Melbourne, 3002, Victoria, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, 3010, Victoria, Australia.

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http://dx.doi.org/10.1016/j.molmed.2013.07.005DOI Listing
November 2013

Dysregulation of the basal RNA polymerase transcription apparatus in cancer.

Nat Rev Cancer 2013 May;13(5):299-314

Division of Cancer Research, Peter MacCallum Cancer Centre, Melbourne 8006, Victoria, Australia.

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http://dx.doi.org/10.1038/nrc3496DOI Listing
May 2013

AKT signalling is required for ribosomal RNA synthesis and progression of Eμ-Myc B-cell lymphoma in vivo.

FEBS J 2013 Nov 13;280(21):5307-16. Epub 2013 Feb 13.

Division of Research, Peter MacCallum Cancer Centre, East Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/febs.12135DOI Listing
November 2013

Relative Expression Levels Rather Than Specific Activity Plays the Major Role in Determining In Vivo AKT Isoform Substrate Specificity.

Enzyme Res 2011 22;2011:720985. Epub 2011 Aug 22.

Growth Control and Differentiation Program, Trescowthick Research Laboratories, Peter MacCallum Cancer Centre, Melbourne, VIC 8006, Australia.

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http://dx.doi.org/10.4061/2011/720985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160084PMC
November 2011

A phospho-proteomic screen identifies novel S6K1 and mTORC1 substrates revealing additional complexity in the signaling network regulating cell growth.

Cell Signal 2011 Aug 1;23(8):1338-47. Epub 2011 Apr 1.

Research Division, Peter MacCallum Cancer Centre, Melbourne, Locked Bag 1, A'Beckett Street, Victoria 8006, Australia.

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http://dx.doi.org/10.1016/j.cellsig.2011.03.016DOI Listing
August 2011

Signaling to the ribosome in cancer--It is more than just mTORC1.

IUBMB Life 2011 Feb;63(2):79-85

Growth Control and Differentiation Program, Peter MacCallum Cancer Centre, St. Andrews Place, East Melbourne, VIC, Australia.

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http://dx.doi.org/10.1002/iub.428DOI Listing
February 2011

Hfp, the Drosophila homolog of the mammalian c-myc transcriptional-repressor and tumor suppressor FIR, inhibits dmyc transcription and cell growth.

Fly (Austin) 2011 Apr-Jun;5(2):129-33. Epub 2011 Apr 1.

Department of Anatomy and Cell Biology, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.4161/fly.5.2.14482DOI Listing
September 2011

The renin-angiotensin system and cancer: old dog, new tricks.

Nat Rev Cancer 2010 Nov 22;10(11):745-59. Epub 2010 Oct 22.

School of Biomedical Sciences, The University of Queensland, St. Lucia, Queensland 4072, Australia.

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http://www.nature.com/articles/nrc2945
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http://dx.doi.org/10.1038/nrc2945DOI Listing
November 2010

Second AKT: the rise of SGK in cancer signalling.

Growth Factors 2010 Dec 5;28(6):394-408. Epub 2010 Oct 5.

Growth Control and Differentiation Program, Peter MacCallum Cancer Centre, Melbourne, 3002, Victoria, Australia.

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http://www.tandfonline.com/doi/full/10.3109/08977194.2010.51
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http://dx.doi.org/10.3109/08977194.2010.518616DOI Listing
December 2010

Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner.

Development 2010 Sep 28;137(17):2875-84. Epub 2010 Jul 28.

Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Melbourne, Australia.

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http://dx.doi.org/10.1242/dev.049585DOI Listing
September 2010

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells.

Genome Res 2010 Mar 28;20(3):351-60. Epub 2010 Jan 28.

Chromosome and Chromatin Research, Murdoch Childrens Research Institute, Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1101/gr.101477.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840985PMC
March 2010

The role of UBF in regulating the structure and dynamics of transcriptionally active rDNA chromatin.

Epigenetics 2009 Aug 6;4(6):374-82. Epub 2009 Aug 6.

Research Division, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.4161/epi.4.6.9449DOI Listing
August 2009

The 'Odd Pols' are even when it comes to controlling cell function. Conference on RNA Polymerases I and III.

EMBO Rep 2008 Dec 31;9(12):1188-92. Epub 2008 Oct 31.

Division of Research, Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne 3002, Victoria, Australia.

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http://dx.doi.org/10.1038/embor.2008.201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603449PMC
December 2008

Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation.

Blood 2008 Sep 11;112(6):2305-17. Epub 2008 Jul 11.

Division of Research, Peter MacCallum Cancer Centre, East Melbourne, Australia.

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http://dx.doi.org/10.1182/blood-2007-09-111856DOI Listing
September 2008

Chromatin organization and expression.

Genome Biol 2008 Apr 14;9(4):305. Epub 2008 Apr 14.

Division of Research, Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne 3002, Victoria, Australia.

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http://dx.doi.org/10.1186/gb-2008-9-4-305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643933PMC
April 2008

Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function.

Growth Factors 2007 Aug;25(4):209-26

Growth Control and Differentiation Program, Trescowthick Research Laboratories, Peter MacCallum Cancer Centre, Melbourne, Australia.

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http://www.tandfonline.com/doi/full/10.1080/0897719070177910
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http://dx.doi.org/10.1080/08977190701779101DOI Listing
August 2007

A specific role for AKT3 in the genesis of ovarian cancer through modulation of G(2)-M phase transition.

Cancer Res 2006 Dec;66(24):11718-25

Growth Control and Differentiation Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-1968DOI Listing
December 2006

Effect of dominant-negative epidermal growth factor receptors on cardiomyocyte hypertrophy.

J Recept Signal Transduct Res 2006 ;26(5-6):659-77

Molecular Endocrinology Laboratory, Baker Heart Research Institute, Prahran, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1080/10799890600923187DOI Listing
March 2007

Expression of constitutively active angiotensin receptors in the rostral ventrolateral medulla increases blood pressure.

Hypertension 2006 Jun 17;47(6):1054-61. Epub 2006 Apr 17.

Department of Physiology, University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1161/01.HYP.0000218576.36574.54DOI Listing
June 2006

Cross talk between corticosteroids and alpha-adrenergic signalling augments cardiomyocyte hypertrophy: a possible role for SGK1.

Cardiovasc Res 2006 Jun 14;70(3):555-65. Epub 2006 Feb 14.

Baker Heart Research Institute, Prahran, Victoria, Australia.

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http://dx.doi.org/10.1016/j.cardiores.2006.02.010DOI Listing
June 2006

Tackling the EGFR in pathological tissue remodelling.

Pulm Pharmacol Ther 2006 24;19(1):74-8. Epub 2005 Jun 24.

Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1016/j.pupt.2005.04.005DOI Listing
May 2006

Cardiovascular role of urotensin II: effect of chronic infusion in the rat.

Peptides 2004 Oct;25(10):1783-8

NHMRC Centre of Clinical Research Excellence in Therapeutics, Departments of Medicine and Epidemiology & Preventive Medicine, Central and Eastern Clinical School, Monash University, Alfred Hospital, Commercial Road, Prahran, Vic. 3181, Australia.

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http://dx.doi.org/10.1016/j.peptides.2004.03.029DOI Listing
October 2004

Urotensin II promotes hypertrophy of cardiac myocytes via mitogen-activated protein kinases.

Mol Endocrinol 2004 Sep 17;18(9):2344-54. Epub 2004 Jun 17.

Molecular Endocrinology, Baker Heart Research Institute, P.O. Box 6492, St. Kilda Road Central, Melbourne 8008, Victoria, Australia.

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http://dx.doi.org/10.1210/me.2003-0309DOI Listing
September 2004

Urotensin II: the old kid in town.

Trends Endocrinol Metab 2004 May-Jun;15(4):175-82

Peter McCallum Cancer Centre, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.tem.2004.03.007DOI Listing
December 2004

Cardiac hypertrophy in vivo is associated with increased expression of the ribosomal gene transcription factor UBF.

FEBS Lett 2003 Jul;548(1-3):79-84

Molecular Cardiology, Baker Heart Research Institute, P.O. Box 6492, St Kilda Road Central, Melbourne, Vic., 8008, Australia.

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http://dx.doi.org/10.1016/s0014-5793(03)00744-0DOI Listing
July 2003

Direct actions of urotensin II on the heart: implications for cardiac fibrosis and hypertrophy.

Circ Res 2003 Aug 3;93(3):246-53. Epub 2003 Jul 3.

NHMRC Centre of Clinical Research Excellence in Therapeutics, Department of MedicineEpidemiology and Preventive Medicine, Monash University Medical School, Prahran, Victoria, Australia.

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http://dx.doi.org/10.1161/01.RES.0000084382.64418.BCDOI Listing
August 2003

Inositol polyphosphate 1-phosphatase is a novel antihypertrophic factor.

J Biol Chem 2002 Jun 3;277(25):22734-42. Epub 2002 Apr 3.

Cellular Biochemistry Laboratory, Baker Medical Research Institute, PO Box 6492, St. Kilda Road Central, Melbourne, 8008, Victoria, Australia.

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http://dx.doi.org/10.1074/jbc.M110405200DOI Listing
June 2002