Rosie M Walker

Rosie M Walker

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Rosie M Walker

Rosie M Walker

Publications by authors named "Rosie M Walker"

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14Publications

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An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort.

Authors:
Olivia K L Hamilton Qian Zhang Allan F McRae Rosie M Walker Stewart W Morris Paul Redmond Archie Campbell Alison D Murray David J Porteous Kathryn L Evans Andrew M McIntosh Ian J Deary Riccardo E Marioni

Int J Obes (Lond) 2019 Sep 6;43(9):1795-1802. Epub 2019 Mar 6.

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41366-018-0262-3DOI Listing
September 2019

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing.

Authors:
Qian Zhang Costanza L Vallerga Rosie M Walker Tian Lin Anjali K Henders Grant W Montgomery Ji He Dongsheng Fan Javed Fowdar Martin Kennedy Toni Pitcher John Pearson Glenda Halliday John B Kwok Ian Hickie Simon Lewis Tim Anderson Peter A Silburn George D Mellick Sarah E Harris Paul Redmond Alison D Murray David J Porteous Christopher S Haley Kathryn L Evans Andrew M McIntosh Jian Yang Jacob Gratten Riccardo E Marioni Naomi R Wray Ian J Deary Allan F McRae Peter M Visscher

Genome Med 2019 08 23;11(1):54. Epub 2019 Aug 23.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.

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http://dx.doi.org/10.1186/s13073-019-0667-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708158PMC
August 2019

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD.

Authors:
Mairead L Bermingham Rosie M Walker Riccardo E Marioni Stewart W Morris Konrad Rawlik Yanni Zeng Archie Campbell Paul Redmond Heather C Whalley Mark J Adams Caroline Hayward Ian J Deary David J Porteous Andrew M McIntosh Kathryn L Evans

EBioMedicine 2019 May 29;43:576-586. Epub 2019 Mar 29.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S23523964193021
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http://dx.doi.org/10.1016/j.ebiom.2019.03.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557748PMC
May 2019

Publisher Correction: Parent of origin genetic effects on methylation in humans are common and influence complex trait variation.

Authors:
Yanni Zeng Carmen Amador Charley Xia Riccardo Marioni Duncan Sproul Rosie M Walker Stewart W Morris Andrew Bretherick Oriol Canela-Xandri Thibaud S Boutin David W Clark Archie Campbell Konrad Rawlik Caroline Hayward Reka Nagy Albert Tenesa David J Porteous James F Wilson Ian J Deary Kathryn L Evans Andrew M McIntosh Pau Navarro Chris S Haley

Nat Commun 2019 May 1;10(1):2069. Epub 2019 May 1.

MRC Human Genetic Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1038/s41467-019-10155-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494888PMC
May 2019

Parent of origin genetic effects on methylation in humans are common and influence complex trait variation.

Authors:
Yanni Zeng Carmen Amador Charley Xia Riccardo Marioni Duncan Sproul Rosie M Walker Stewart W Morris Andrew Bretherick Oriol Canela-Xandri Thibaud S Boutin David W Clark Archie Campbell Konrad Rawlik Caroline Hayward Reka Nagy Albert Tenesa David J Porteous James F Wilson Ian J Deary Kathryn L Evans Andrew M McIntosh Pau Navarro Chris S Haley

Nat Commun 2019 03 27;10(1):1383. Epub 2019 Mar 27.

MRC Human Genetic Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1038/s41467-019-09301-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437195PMC
March 2019

Assessment of dried blood spots for DNA methylation profiling.

Authors:
Rosie M Walker Louise MacGillivray Sarah McCafferty Nicola Wrobel Lee Murphy Shona M Kerr Stewart W Morris Archie Campbell Andrew M McIntosh David J Porteous Kathryn L Evans

Wellcome Open Res 2019 6;4:44. Epub 2019 Mar 6.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Midlothian, EH4 2XU, UK.

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https://wellcomeopenresearch.org/articles/4-44/v1
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http://dx.doi.org/10.12688/wellcomeopenres.15136.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446498PMC
March 2019

Epigenetic signatures of starting and stopping smoking.

Authors:
Daniel L McCartney Anna J Stevenson Robert F Hillary Rosie M Walker Mairead L Bermingham Stewart W Morris Toni-Kim Clarke Archie Campbell Alison D Murray Heather C Whalley David J Porteous Peter M Visscher Andrew M McIntosh Kathryn L Evans Ian J Deary Riccardo E Marioni

EBioMedicine 2018 Nov 30;37:214-220. Epub 2018 Oct 30.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, Scotland, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.10.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286188PMC
November 2018

DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies.

Authors:
Olivera Story Jovanova Ivana Nedeljkovic Derek Spieler Rosie M Walker Chunyu Liu Michelle Luciano Jan Bressler Jennifer Brody Amanda J Drake Kathryn L Evans Rahul Gondalia Sonja Kunze Brigitte Kuhnel Jari Lahti Rozenn N Lemaitre Riccardo E Marioni Brenton Swenson Jayandra Jung Himali Hongsheng Wu Yun Li Allan F McRae Tom C Russ James Stewart Zhiying Wang Guosheng Zhang Karl-Heinz Ladwig Andre G Uitterlinden Xiuqing Guo Annette Peters Katri Räikkönen John M Starr Melanie Waldenberger Naomi R Wray Eric A Whitsel Nona Sotoodehnia Sudha Seshadri David J Porteous Joyce van Meurs Thomas H Mosley Andrew M McIntosh Michael M Mendelson Daniel Levy Lifang Hou Johan G Eriksson Myriam Fornage Ian J Deary Andrea Baccarelli Henning Tiemeier Najaf Amin

JAMA Psychiatry 2018 Sep;75(9):949-959

Department of Epidemiology, Erasmus MC-University Medical Center Rotterdam, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1001/jamapsychiatry.2018.1725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142917PMC
September 2018

Epigenetic prediction of complex traits and death.

Authors:
Daniel L McCartney Robert F Hillary Anna J Stevenson Stuart J Ritchie Rosie M Walker Qian Zhang Stewart W Morris Mairead L Bermingham Archie Campbell Alison D Murray Heather C Whalley Catharine R Gale David J Porteous Chris S Haley Allan F McRae Naomi R Wray Peter M Visscher Andrew M McIntosh Kathryn L Evans Ian J Deary Riccardo E Marioni

Genome Biol 2018 09 27;19(1):136. Epub 2018 Sep 27.

Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1186/s13059-018-1514-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158884PMC
September 2018

Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease.

Authors:
Daniel L McCartney Anna J Stevenson Rosie M Walker Jude Gibson Stewart W Morris Archie Campbell Alison D Murray Heather C Whalley David J Porteous Andrew M McIntosh Kathryn L Evans Ian J Deary Riccardo E Marioni

Alzheimers Dement (Amst) 2018 21;10:429-437. Epub 2018 Jun 21.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland.

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http://dx.doi.org/10.1016/j.dadm.2018.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111045PMC
June 2018

Altered DNA methylation associated with a translocation linked to major mental illness.

Authors:
Daniel L McCartney Rosie M Walker Stewart W Morris Susan M Anderson Barbara J Duff Riccardo E Marioni J Kirsty Millar Shane E McCarthy Niamh M Ryan Stephen M Lawrie Andrew R Watson Douglas H R Blackwood Pippa A Thomson Andrew M McIntosh W Richard McCombie David J Porteous Kathryn L Evans

NPJ Schizophr 2018 Mar 19;4(1). Epub 2018 Mar 19.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1038/s41537-018-0047-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859082PMC
March 2018

Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip.

Authors:
Daniel L McCartney Rosie M Walker Stewart W Morris Andrew M McIntosh David J Porteous Kathryn L Evans

Genom Data 2016 Sep 26;9:22-4. Epub 2016 May 26.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, Western General Hospital, The University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, The University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, UK.

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http://dx.doi.org/10.1016/j.gdata.2016.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909830PMC
September 2016

The DISC1 promoter: characterization and regulation by FOXP2.

Authors:
Rosie M Walker Alison E Hill Alice C Newman Gillian Hamilton Helen S Torrance Susan M Anderson Fumiaki Ogawa Pelagia Derizioti Jérôme Nicod Sonja C Vernes Simon E Fisher Pippa A Thomson David J Porteous Kathryn L Evans

Hum Mol Genet 2012 Jul 20;21(13):2862-72. Epub 2012 Mar 20.

Medical Genetics Section, Molecular Medicine Centre, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1093/hmg/dds111DOI Listing
July 2012

Association analysis of Neuregulin 1 candidate regions in schizophrenia and bipolar disorder.

Authors:
Rosie M Walker Andrea Christoforou Pippa A Thomson Kevin A McGhee Alan Maclean Thomas W Mühleisen Jana Strohmaier Vanessa Nieratschker Markus M Nöthen Marcella Rietschel Sven Cichon Stewart W Morris Omer Jilani David Stclair Douglas H Blackwood Walter J Muir David J Porteous Kathryn L Evans

Neurosci Lett 2010 Jun 7;478(1):9-13. Epub 2010 May 7.

Medical Genetics Section, Centre for Molecular Medicine and Institute of Genetics and Molecular Medicine, Molecular Medicine Centre, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1016/j.neulet.2010.04.056DOI Listing
June 2010