Rose A Maciewicz

Rose A Maciewicz

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Rose A Maciewicz

Rose A Maciewicz

Publications by authors named "Rose A Maciewicz"

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Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases.

J Exp Med 2019 Sep 9;216(9):2184-2201. Epub 2019 Jul 9.

Manchester Collaborative Centre for Inflammation Research, the University of Manchester, Manchester, UK

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http://dx.doi.org/10.1084/jem.20171978DOI Listing
September 2019

Phenotypic screening identifies Axl kinase as a negative regulator of an alveolar epithelial cell phenotype.

Lab Invest 2017 09 29;97(9):1047-1062. Epub 2017 May 29.

Innovative Medicines and Early Development, Respiratory, Inflammation and Autoimmunity, AstraZeneca AB, Mölndal, Sweden.

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http://www.nature.com/doifinder/10.1038/labinvest.2017.52
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http://dx.doi.org/10.1038/labinvest.2017.52DOI Listing
September 2017

Association of Beta-Blocker Use With Less Prevalent Joint Pain and Lower Opioid Requirement in People With Osteoarthritis.

Arthritis Care Res (Hoboken) 2017 07 7;69(7):1076-1081. Epub 2017 Jun 7.

University of Nottingham, Nottingham City Hospital, and Arthritis Research UK Pain Centre, Nottingham, UK.

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http://dx.doi.org/10.1002/acr.23091DOI Listing
July 2017

Bone Area Provides a Responsive Outcome Measure for Bone Changes in Short-term Knee Osteoarthritis Studies.

J Rheumatol 2016 12 1;43(12):2179-2182. Epub 2016 Oct 1.

From the Imorphics; Biomedical Imaging Institute, Manchester Academic Health Sciences Centre, University of Manchester, Manchester; Respiratory, Inflammation, Autoimmunity Innovative Medicines and Early Development (IMED), AstraZeneca, Cambridge; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK; Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia; Rheumatology Department, Royal North Shore Hospital, St. Leonards, Australia.

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http://dx.doi.org/10.3899/jrheum.151118DOI Listing
December 2016

The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.

Mucosal Immunol 2015 Sep 21;8(5):1021-1030. Epub 2015 Jan 21.

Manchester Collaborative Centre for Inflammation Research, Manchester University, Core Technology Facility, 46 Grafton Street, Manchester. M13 9NT, UK.

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http://www.nature.com/articles/mi2014129
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http://dx.doi.org/10.1038/mi.2014.129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430298PMC
September 2015

Beer and wine consumption and risk of knee or hip osteoarthritis: a case control study.

Arthritis Res Ther 2015 Feb 5;17:23. Epub 2015 Feb 5.

Academic Rheumatology, University of Nottingham, Clinical Sciences Building, Nottingham City Hospital, Nottingham, NG5 1PB, UK.

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http://dx.doi.org/10.1186/s13075-015-0534-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355424PMC
February 2015

Self-reported adult footwear and the risks of lower limb osteoarthritis: the GOAL case control study.

BMC Musculoskelet Disord 2014 Sep 20;15:308. Epub 2014 Sep 20.

Division of Rheumatology, Orthopaedics and Dermatology, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1186/1471-2474-15-308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190490PMC
September 2014

Evidence of changes to skeletal muscle contractile properties during the initiation of disease in the ageing guinea pig model of osteoarthritis.

Longev Healthspan 2013 Dec 1;2(1):15. Epub 2013 Dec 1.

Nutritional Sciences, School of Biosciences, Sutton Bonington Campus, Sutton Bonington, University of Nottingham, Nottingham LE12 5RD, England.

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http://dx.doi.org/10.1186/2046-2395-2-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177544PMC
December 2013

The genetic contribution to severe post-traumatic osteoarthritis.

Ann Rheum Dis 2013 Oct 26;72(10):1687-90. Epub 2013 Jan 26.

Academic Rheumatology, Nottingham City Hospital, Nottingham, UK.

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http://dx.doi.org/10.1136/annrheumdis-2012-202562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786638PMC
October 2013

Hydantoin based inhibitors of MMP13--discovery of AZD6605.

Bioorg Med Chem Lett 2013 Aug 10;23(16):4705-12. Epub 2013 Jun 10.

Oncology Innovative Medicines, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, MA 02451, USA.

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http://dx.doi.org/10.1016/j.bmcl.2013.05.089DOI Listing
August 2013

Genetic contribution to radiographic severity in osteoarthritis of the knee.

Ann Rheum Dis 2012 Sep 21;71(9):1537-40. Epub 2012 May 21.

Correspondence to Dr Ana M Valdes, Kings College London, Twin Research Unit, St Thomas Hospital, Lambeth Palace Rd, London SE1 7EH, UK.

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http://ard.bmj.com/content/71/9/1537.full.pdf
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http://ard.bmj.com/cgi/doi/10.1136/annrheumdis-2012-201382
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http://dx.doi.org/10.1136/annrheumdis-2012-201382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414227PMC
September 2012

Inverse relationship between preoperative radiographic severity and postoperative pain in patients with osteoarthritis who have undergone total joint arthroplasty.

Semin Arthritis Rheum 2012 Feb 24;41(4):568-75. Epub 2011 Aug 24.

Department of Twin Research, King's College London, St. Thomas' Hospital, London, UK.

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http://dx.doi.org/10.1016/j.semarthrit.2011.07.002DOI Listing
February 2012

Mild acetabular dysplasia and risk of osteoarthritis of the hip: a case-control study.

Ann Rheum Dis 2010 Oct 14;69(10):1774-8. Epub 2010 May 14.

Academic Rheumatology, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1136/ard.2009.127076DOI Listing
October 2010

Relationship of serum markers of cartilage metabolism to imaging and clinical outcome measures of knee joint structure.

Ann Rheum Dis 2010 Oct 15;69(10):1816-22. Epub 2010 Jun 15.

Department of Epidemiology and Preventive Medicine, Monash University Medical School, Alfred Hospital, Prahran, Victoria, Australia.

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http://dx.doi.org/10.1136/ard.2009.124420DOI Listing
October 2010

Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes.

Arthritis Rheum 2010 Sep;62(9):2688-95

Department of Twin Research and Genetic Epidemiology, King's College London and St. Thomas' Hospital, London, UK.

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http://dx.doi.org/10.1002/art.27574DOI Listing
September 2010

Anatomically corresponded regional analysis of cartilage in asymptomatic and osteoarthritic knees by statistical shape modelling of the bone.

IEEE Trans Med Imaging 2010 Aug 8;29(8):1541-59. Epub 2010 Apr 8.

Imaging Science and Biomedical Engineering, School of Cancer and Enabling Sciences, The University of Manchester, M13 9PT Manchester, UK.

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http://dx.doi.org/10.1109/TMI.2010.2047653DOI Listing
August 2010

Markers of bone formation and resorption identify subgroups of patients with clinical knee osteoarthritis who have reduced rates of cartilage loss.

J Rheumatol 2010 Jun 15;37(6):1252-9. Epub 2010 Apr 15.

Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, Alfred Hospital, Melbourne, Victoria 3004, Australia.

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http://dx.doi.org/10.3899/jrheum.091055DOI Listing
June 2010

Self-reported knee and foot alignments in early adult life and risk of osteoarthritis.

Arthritis Care Res (Hoboken) 2010 Apr;62(4):489-95

Academic Rheumatology, Clinical Sciences Building, University of Nottingham, City Hospital, Nottingham, UK.

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http://dx.doi.org/10.1002/acr.20169DOI Listing
April 2010

Characterization of fibrodysplasia in the dog following inhibition of metalloproteinases.

Toxicol Pathol 2009 Dec;37(7):860-72

AstraZeneca Pharmaceuticals - Safety Assessment, Mereside, Alderley Park, Macclesfield, United Kingdom.

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http://dx.doi.org/10.1177/0192623309347909DOI Listing
December 2009

Can increased understanding of the role of lung development and aging drive new advances in chronic obstructive pulmonary disease?

Proc Am Thorac Soc 2009 Dec;6(7):614-7

Pulmonary and Critical Care Medicine, University of Nebraska Medical Center, 985910 Nebraska Medical Center, Omaha, NE 68198-5910, USA.

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http://dx.doi.org/10.1513/pats.200908-094RMDOI Listing
December 2009

Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized.

Arthritis Res Ther 2009 26;11(1):R11. Epub 2009 Jan 26.

Division of Research, New England Baptist Hospital, 125 Parker Hill Avenue, Boston, MA 02120, USA.

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http://dx.doi.org/10.1186/ar2601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688243PMC
September 2009

Nonspherical femoral head shape (pistol grip deformity), neck shaft angle, and risk of hip osteoarthritis: a case-control study.

Arthritis Rheum 2008 Oct;58(10):3172-82

University of Nottingham, Nottingham University Hospitals Trust, Nottingham, UK.

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http://dx.doi.org/10.1002/art.23939DOI Listing
October 2008

Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells.

J Biol Chem 2004 May 16;279(21):22377-86. Epub 2004 Feb 16.

Wellcome Trust Centre for Cell-Matrix Research, School of Biological Sciences, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT.

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http://dx.doi.org/10.1074/jbc.M400180200DOI Listing
May 2004