Rosario Sanchez-Pernaute

Rosario Sanchez-Pernaute

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Rosario Sanchez-Pernaute

Rosario Sanchez-Pernaute

Publications by authors named "Rosario Sanchez-Pernaute"

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Chimeras for the twenty-first century.

Crit Rev Biotechnol 2020 Feb 13:1-9. Epub 2020 Feb 13.

Preclinical Department, Andalusian Network for Advanced Therapies, Fundación Progreso y Salud, Sevilla, Spain.

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http://dx.doi.org/10.1080/07388551.2019.1679084DOI Listing
February 2020

Small fiber neuropathy and phosphorylated alpha-synuclein in the skin of E46K-SNCA mutation carriers.

Parkinsonism Relat Disord 2019 08 5;65:139-145. Epub 2019 Jun 5.

Neurodegenerative Diseases Group, Biocruces Bizkaia Health Research Institute, Cruces-Barakaldo, Bizkaia, Spain; Neurology Department, Cruces University Hospital, Cruces-Barakaldo, Bizkaia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.05.038DOI Listing
August 2019

Sox-2 Positive Neural Progenitors in the Primate Striatum Undergo Dynamic Changes after Dopamine Denervation.

PLoS One 2013 18;8(6):e66377. Epub 2013 Jun 18.

Laboratory of Regenerative Therapy, Neuroscience Division, Centro de Investigación Médica Aplicada and Department of Neurology, Clínica Universidad de Navarra, Pamplona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066377PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688912PMC
October 2017

Mitochondrial respiratory chain disorganization in Parkinson's disease-relevant PINK1 and DJ1 mutants.

Neurochem Int 2017 Oct 11;109:101-105. Epub 2017 Apr 11.

University of Salamanca, CIBERFES, Institute of Functional Biology and Genomics (IBFG), CSIC, 37007 Salamanca, Spain; Institute of Biomedical Research of Salamanca (IBSAL), University Hospital of Salamanca, 37007 Salamanca, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuint.2017.03.023DOI Listing
October 2017

Fast and Efficient Neural Conversion of Human Hematopoietic Cells.

Curr Protoc Stem Cell Biol 2016 Nov;39(1):1F.15.1-1F.15.20

Center for Regenerative Medicine in Barcelona, (CMRB), Barcelona, Spain.

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http://dx.doi.org/10.1002/cpsc.16DOI Listing
November 2016

Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons.

J Neuroinflammation 2016 11 18;13(1):295. Epub 2016 Nov 18.

Laboratory of Stem Cells and Neural Repair, Inbiomed, Paseo Mikeletegi, 81, E-20009, San Sebastian, Spain.

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http://dx.doi.org/10.1186/s12974-016-0761-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116223PMC
November 2016

Selection Based on FOXA2 Expression Is Not Sufficient to Enrich for Dopamine Neurons From Human Pluripotent Stem Cells.

Stem Cells Transl Med 2014 Sep 14;3(9):1032-42. Epub 2014 Jul 14.

Laboratory of Stem Cells and Neural Repair and Cytometry and Advanced Optical Microscopy Facility, Inbiomed, San Sebastian, Spain; STEMCELL Technologies, Inc., Vancouver, British Columbia, Canada; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, USA

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http://dx.doi.org/10.5966/sctm.2014-0011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149300PMC
September 2014

Leucine-rich repeat kinase 2 modulates cyclooxygenase 2 and the inflammatory response in idiopathic and genetic Parkinson's disease.

Neurobiol Aging 2014 May 22;35(5):1116-24. Epub 2013 Nov 22.

Laboratory of Stem Cells and Neural Repair, Fundación Inbiomed, San Sebastián, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.11.018DOI Listing
May 2014

Buspirone anti-dyskinetic effect is correlated with temporal normalization of dysregulated striatal DRD1 signalling in L-DOPA-treated rats.

Neuropharmacology 2014 Apr 10;79:726-37. Epub 2013 Dec 10.

Laboratory of Stem Cells and Neural Repair, Inbiomed, P. Mikeletegi, 81, 20009 San Sebastian, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2013.11.024DOI Listing
April 2014

The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway.

Cell Mol Life Sci 2013 Jan 8;70(1):121-36. Epub 2012 Jul 8.

Departamento de Bioquímica y Biología Molecular y Genética, E. Enfermería y T.O., Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Universidad de Extremadura, Avda Universidad, s/n, 10003, Cáceres, Spain.

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http://dx.doi.org/10.1007/s00018-012-1061-yDOI Listing
January 2013

The MAPK1/3 pathway is essential for the deregulation of autophagy observed in G2019S LRRK2 mutant fibroblasts.

Autophagy 2012 Oct 23;8(10):1537-9. Epub 2012 Aug 23.

Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Departamento de Bioquímica y Biología Molecular y Genética, E. Enfermería y T.O., Universidad de Extremadura, Cáceres, Spain.

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http://dx.doi.org/10.4161/auto.21270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463455PMC
October 2012

Cellular programming and reprogramming: sculpting cell fate for the production of dopamine neurons for cell therapy.

Stem Cells Int 2012 4;2012:412040. Epub 2012 Sep 4.

Laboratory of Stem Cells and Neural Repair, Fundacion Inbiomed, Paseo Mikeletegi 81, 20009 San Sebastian, Spain.

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http://downloads.hindawi.com/journals/sci/2012/412040.pdf
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http://www.hindawi.com/journals/sci/2012/412040/
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http://dx.doi.org/10.1155/2012/412040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441013PMC
September 2012

Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease.

Brain 2008 Aug 22;131(Pt 8):2127-39. Epub 2008 Jul 22.

McLean Hospital/Harvard University Udall Parkinson's Disease Research Center of Excellence, McLean Hospital, Belmont, MA 02478, USA.

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http://dx.doi.org/10.1093/brain/awn144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724903PMC
August 2008

Nociceptin/orphanin FQ receptor blockade attenuates MPTP-induced parkinsonism.

Neurobiol Dis 2008 Jun 8;30(3):430-8. Epub 2008 Mar 8.

Department of Experimental and Clinical Medicine, Section of Pharmacology, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1016/j.nbd.2008.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605654PMC
June 2008

Markers and methods for cell sorting of human embryonic stem cell-derived neural cell populations.

Stem Cells 2007 Sep 21;25(9):2257-68. Epub 2007 Jun 21.

Center for Neuroregeneration Research, McLean Hospital/Harvard Medical School, Belmont, Massachusetts 02478, USA.

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http://dx.doi.org/10.1634/stemcells.2006-0744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238728PMC
September 2007

In vivo evidence of D3 dopamine receptor sensitization in parkinsonian primates and rodents with l-DOPA-induced dyskinesias.

Neurobiol Dis 2007 Aug 18;27(2):220-7. Epub 2007 May 18.

McLean Hospital/Harvard University Udall Parkinson's Disease Research Center of Excellence, McLean Hospital, 115 Mill St., Belmont, MA 02478, USA.

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http://dx.doi.org/10.1016/j.nbd.2007.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674779PMC
August 2007

Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using the bone morphogenic protein antagonist noggin.

Stem Cells 2007 Feb 12;25(2):411-8. Epub 2006 Oct 12.

Center for Neuroregeneration Research, Udall Parkinson's Disease Center of Excellence, McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, USA.

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http://dx.doi.org/10.1634/stemcells.2006-0380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667240PMC
February 2007

Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC.

Mol Ther 2006 Oct 7;14(4):564-70. Epub 2006 Jul 7.

Department of Neurosurgery, University of California at San Francisco, Room MCB 226, 1855 Folsom Street, San Francisco, CA 94103-0555, USA.

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http://dx.doi.org/10.1016/j.ymthe.2006.05.005DOI Listing
October 2006

Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft.

Eur J Neurosci 2006 Oct;24(7):1885-96

McLean Hospital/Harvard University Udall Parkinson's Disease Research Center of Excellence, 115 Mill St, Belmont, MA 02478, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2006.05093.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602801PMC
October 2006

Tailoring human embryonic stem cells for neurodegenerative disease therapy.

Curr Opin Investig Drugs 2006 Jul;7(7):614-8

Center for Neuroregeneration Research, Udall Parkinson's Disease Center of Excellence, McLean Hospital, Belmont, MA 02478, USA.

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July 2006

Insights into Parkinson's disease models and neurotoxicity using non-invasive imaging.

Toxicol Appl Pharmacol 2005 Sep;207(2 Suppl):251-6

McLean Hospital/Harvard University, Udall Parkinson's Disease Research Center of Excellence, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA.

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http://dx.doi.org/10.1016/j.taap.2005.02.039DOI Listing
September 2005

Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation.

Stem Cells 2005 Aug 7;23(7):914-22. Epub 2005 Jun 7.

McLean Hospital/Harvard University Udall Parkinson's Disease Research Center of Excellence and Neuroregeneration Laboratories, McLean Hospital, 115 Mill St., Belmont, Massachusetts 02478, USA.

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http://dx.doi.org/10.1634/stemcells.2004-0172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654596PMC
August 2005

Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease.

Brain 2005 Jul 4;128(Pt 7):1498-510. Epub 2005 May 4.

Dalhousie University and Queen Elizabeth II Health Science Center, Division of Neurosurgery and Neuroscience, Halifax, Canada.

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http://dx.doi.org/10.1093/brain/awh510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2610438PMC
July 2005

Mapping dopamine function in primates using pharmacologic magnetic resonance imaging.

J Neurosci 2004 Oct;24(43):9553-60

Massachusetts General Hospital (MGH) Nuclear Magnetic Resonance Center, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts 02129, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1558-04.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629666PMC
October 2004

Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease.

J Neuroinflammation 2004 May 17;1(1). Epub 2004 May 17.

McLean Hospital/Harvard University Udall Parkinson's Disease Research Center of Excellence, Belmont, Massachusetts, USA.

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http://dx.doi.org/10.1186/1742-2094-1-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC483059PMC
May 2004

Preclinical models of Parkinson's disease.

Curr Protoc Toxicol 2004 Feb;Chapter 1:Unit1.8

University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1002/0471140856.tx0108s18DOI Listing
February 2004

Progressive and extensive dopaminergic degeneration induced by convection-enhanced delivery of 6-hydroxydopamine into the rat striatum: a novel rodent model of Parkinson disease.

J Neurosurg 2003 Jan;98(1):136-44

Molecular Therapeutics Section, Laboratory of Molecular Medicine and Neuroscience, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.3171/jns.2003.98.1.0136DOI Listing
January 2003

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

Nature 2002 Jul 20;418(6893):50-6. Epub 2002 Jun 20.

Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nature00900DOI Listing
July 2002

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model.

Proc Natl Acad Sci U S A 2002 Feb 8;99(4):2344-9. Epub 2002 Jan 8.

Udall Parkinson's Disease Research Center of Excellence, Neuroregeneration Laboratories, and Molecular Neurobiology Laboratory, McLean Hospital/Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA.

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http://dx.doi.org/10.1073/pnas.022438099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC122367PMC
February 2002