Rosalind A Eeles

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Rosalind A Eeles

Publications by authors named "Rosalind A Eeles"

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Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.

Authors:
Fredrick R Schumacher Ali Amin Al Olama Sonja I Berndt Sara Benlloch Mahbubl Ahmed Edward J Saunders Tokhir Dadaev Daniel Leongamornlert Ezequiel Anokian Clara Cieza-Borrella Chee Goh Mark N Brook Xin Sheng Laura Fachal Joe Dennis Jonathan Tyrer Kenneth Muir Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis J Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail P Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Håkansson Catharine M L West Alison M Dunning Neil Burnet Lorelei A Mucci Edward Giovannucci Gerald L Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry S Rosenstein Sarah L Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weischer Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Sandeep Singhal Chavdar Slavov Vanio Mitev Matthew Parliament Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Zuxi Cui Peter Kraft Christopher I Amos David V Conti Douglas F Easton Fredrik Wiklund Stephen J Chanock Brian E Henderson Zsofia Kote-Jarai Christopher A Haiman Rosalind A Eeles

Nat Genet 2018 Jun 11. Epub 2018 Jun 11.

Institute of Cancer Research, London, UK.

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June 2018

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

Authors:
Tokhir Dadaev Edward J Saunders Paul J Newcombe Ezequiel Anokian Daniel A Leongamornlert Mark N Brook Clara Cieza-Borrella Martina Mijuskovic Sarah Wakerell Ali Amin Al Olama Fredrick R Schumacher Sonja I Berndt Sara Benlloch Mahbubl Ahmed Chee Goh Xin Sheng Zhuo Zhang Kenneth Muir Koveela Govindasami Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Hakansson Catharine West Alison M Dunning Neil Burnet Lorelei Mucci Edward Giovannucci Gerald Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry Rosenstein Sarah Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Laura Fachal Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weisher Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Chavdar Slavov Vanio Mitev Matthew Parliament Sandeep Singhal Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Andrzej Kierzek Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Peter Kraft Matthew Freedman Fredrik Wiklund Stephen Chanock Brian E Henderson Douglas F Easton Christopher A Haiman Rosalind A Eeles David V Conti Zsofia Kote-Jarai

Nat Commun 2018 Jun 11;9(1):2256. Epub 2018 Jun 11.

The Institute of Cancer Research, London, SW7 3RP, UK.

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June 2018

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.

Nat Genet 2018 May 16;50(5):682-692. Epub 2018 Apr 16.

The Institute of Cancer Research, London, UK.

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May 2018

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.

Authors:
Christos Mikropoulos Christina G Hutten Selkirk Sibel Saya Elizabeth Bancroft Emily Vertosick Tokhir Dadaev Charles Brendler Elizabeth Page Alexander Dias D Gareth Evans Jeanette Rothwell Lovise Maehle Karol Axcrona Kate Richardson Diana Eccles Thomas Jensen Palle J Osther Christi J van Asperen Hans Vasen Lambertus A Kiemeney Janneke Ringelberg Cezary Cybulski Dominika Wokolorczyk Rachel Hart Wayne Glover Jimmy Lam Louise Taylor Monica Salinas Lidia Feliubadaló Rogier Oldenburg Ruben Cremers Gerald Verhaegh Wendy A van Zelst-Stams Jan C Oosterwijk Jackie Cook Derek J Rosario Saundra S Buys Tom Conner Susan Domchek Jacquelyn Powers Margreet G E M Ausems Manuel R Teixeira Sofia Maia Louise Izatt Rita Schmutzler Kerstin Rhiem William D Foulkes Talia Boshari Rosemarie Davidson Marielle Ruijs Apollonia T J M Helderman-van den Enden Lesley Andrews Lisa Walker Katie Snape Alex Henderson Irene Jobson Geoffrey J Lindeman Annelie Liljegren Marion Harris Muriel A Adank Judy Kirk Amy Taylor Rachel Susman Rakefet Chen-Shtoyerman Nicholas Pachter Allan Spigelman Lucy Side Janez Zgajnar Josefina Mora Carole Brewer Neus Gadea Angela F Brady David Gallagher Theo van Os Alan Donaldson Vigdis Stefansdottir Julian Barwell Paul A James Declan Murphy Eitan Friedman Nicola Nicolai Lynn Greenhalgh Elias Obeid Vedang Murthy Lucia Copakova John McGrath Soo-Hwang Teo Sara Strom Karin Kast Daniel A Leongamornlert Anthony Chamberlain Jenny Pope Anna C Newlin Neil Aaronson Audrey Ardern-Jones Chris Bangma Elena Castro David Dearnaley Jorunn Eyfjord Alison Falconer Christopher S Foster Henrik Gronberg Freddie C Hamdy Oskar Johannsson Vincent Khoo Jan Lubinski Eli Marie Grindedal Joanne McKinley Kylie Shackleton Anita V Mitra Clare Moynihan Gad Rennert Mohnish Suri Karen Tricker Sue Moss Zsofia Kote-Jarai Andrew Vickers Hans Lilja Brian T Helfand Rosalind A Eeles

Br J Cancer 2018 Mar 6;118(6):e17. Epub 2018 Mar 6.

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March 2018

Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition.

Authors:
Christos Mikropoulos Christina G Hutten Selkirk Sibel Saya Elizabeth Bancroft Emily Vertosick Tokhir Dadaev Charles Brendler Elizabeth Page Alexander Dias D Gareth Evans Jeanette Rothwell Lovise Maehle Karol Axcrona Kate Richardson Diana Eccles Thomas Jensen Palle J Osther Christi J van Asperen Hans Vasen Lambertus A Kiemeney Janneke Ringelberg Cezary Cybulski Dominika Wokolorczyk Rachel Hart Wayne Glover Jimmy Lam Louise Taylor Monica Salinas Lidia Feliubadaló Rogier Oldenburg Ruben Cremers Gerald Verhaegh Wendy A van Zelst-Stams Jan C Oosterwijk Jackie Cook Derek J Rosario Saundra S Buys Tom Conner Susan Domchek Jacquelyn Powers Margreet Gem Ausems Manuel R Teixeira Sofia Maia Louise Izatt Rita Schmutzler Kerstin Rhiem William D Foulkes Talia Boshari Rosemarie Davidson Marielle Ruijs Apollonia Tjm Helderman-van den Enden Lesley Andrews Lisa Walker Katie Snape Alex Henderson Irene Jobson Geoffrey J Lindeman Annelie Liljegren Marion Harris Muriel A Adank Judy Kirk Amy Taylor Rachel Susman Rakefet Chen-Shtoyerman Nicholas Pachter Allan Spigelman Lucy Side Janez Zgajnar Josefina Mora Carole Brewer Neus Gadea Angela F Brady David Gallagher Theo van Os Alan Donaldson Vigdis Stefansdottir Julian Barwell Paul A James Declan Murphy Eitan Friedman Nicola Nicolai Lynn Greenhalgh Elias Obeid Vedang Murthy Lucia Copakova John McGrath Soo-Hwang Teo Sara Strom Karin Kast Daniel A Leongamornlert Anthony Chamberlain Jenny Pope Anna C Newlin Neil Aaronson Audrey Ardern-Jones Chris Bangma Elena Castro David Dearnaley Jorunn Eyfjord Alison Falconer Christopher S Foster Henrik Gronberg Freddie C Hamdy Oskar Johannsson Vincent Khoo Jan Lubinski Eli Marie Grindedal Joanne McKinley Kylie Shackleton Anita V Mitra Clare Moynihan Gad Rennert Mohnish Suri Karen Tricker Sue Moss Zsofia Kote-Jarai Andrew Vickers Hans Lilja Brian T Helfand Rosalind A Eeles

Br J Cancer 2018 Jan 4;118(2):266-276. Epub 2018 Jan 4.

The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, UK.

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January 2018

A review of prostate cancer genome wide association studies (GWAS).

Cancer Epidemiol Biomarkers Prev 2018 Jan 18. Epub 2018 Jan 18.

Genetics & Epidemiology, The Institute of Cancer Research.

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January 2018

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.

J Natl Cancer Inst 2017 Aug;109(8)

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.

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August 2017

Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium.

Cancer Epidemiol Biomarkers Prev 2017 06 23;26(6):816-825. Epub 2017 Jan 23.

National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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June 2017

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Authors:
Philip C Haycock Stephen Burgess Aayah Nounu Jie Zheng George N Okoli Jack Bowden Kaitlin Hazel Wade Nicholas J Timpson David M Evans Peter Willeit Abraham Aviv Tom R Gaunt Gibran Hemani Massimo Mangino Hayley Patricia Ellis Kathreena M Kurian Karen A Pooley Rosalind A Eeles Jeffrey E Lee Shenying Fang Wei V Chen Matthew H Law Lisa M Bowdler Mark M Iles Qiong Yang Bradford B Worrall Hugh Stephen Markus Rayjean J Hung Chris I Amos Amanda B Spurdle Deborah J Thompson Tracy A O'Mara Brian Wolpin Laufey Amundadottir Rachael Stolzenberg-Solomon Antonia Trichopoulou N Charlotte Onland-Moret Eiliv Lund Eric J Duell Federico Canzian Gianluca Severi Kim Overvad Marc J Gunter Rosario Tumino Ulrika Svenson Andre van Rij Annette F Baas Matthew J Bown Nilesh J Samani Femke N G van t'Hof Gerard Tromp Gregory T Jones Helena Kuivaniemi James R Elmore Mattias Johansson James Mckay Ghislaine Scelo Robert Carreras-Torres Valerie Gaborieau Paul Brennan Paige M Bracci Rachel E Neale Sara H Olson Steven Gallinger Donghui Li Gloria M Petersen Harvey A Risch Alison P Klein Jiali Han Christian C Abnet Neal D Freedman Philip R Taylor John M Maris Katja K Aben Lambertus A Kiemeney Sita H Vermeulen John K Wiencke Kyle M Walsh Margaret Wrensch Terri Rice Clare Turnbull Kevin Litchfield Lavinia Paternoster Marie Standl Gonçalo R Abecasis John Paul SanGiovanni Yong Li Vladan Mijatovic Yadav Sapkota Siew-Kee Low Krina T Zondervan Grant W Montgomery Dale R Nyholt David A van Heel Karen Hunt Dan E Arking Foram N Ashar Nona Sotoodehnia Daniel Woo Jonathan Rosand Mary E Comeau W Mark Brown Edwin K Silverman John E Hokanson Michael H Cho Jennie Hui Manuel A Ferreira Philip J Thompson Alanna C Morrison Janine F Felix Nicholas L Smith Angela M Christiano Lynn Petukhova Regina C Betz Xing Fan Xuejun Zhang Caihong Zhu Carl D Langefeld Susan D Thompson Feijie Wang Xu Lin David A Schwartz Tasha Fingerlin Jerome I Rotter Mary Frances Cotch Richard A Jensen Matthias Munz Henrik Dommisch Arne S Schaefer Fang Han Hanna M Ollila Ryan P Hillary Omar Albagha Stuart H Ralston Chenjie Zeng Wei Zheng Xiao-Ou Shu Andre Reis Steffen Uebe Ulrike Hüffmeier Yoshiya Kawamura Takeshi Otowa Tsukasa Sasaki Martin Lloyd Hibberd Sonia Davila Gang Xie Katherine Siminovitch Jin-Xin Bei Yi-Xin Zeng Asta Försti Bowang Chen Stefano Landi Andre Franke Annegret Fischer David Ellinghaus Carlos Flores Imre Noth Shwu-Fan Ma Jia Nee Foo Jianjun Liu Jong-Won Kim David G Cox Olivier Delattre Olivier Mirabeau Christine F Skibola Clara S Tang Merce Garcia-Barcelo Kai-Ping Chang Wen-Hui Su Yu-Sun Chang Nicholas G Martin Scott Gordon Tracey D Wade Chaeyoung Lee Michiaki Kubo Pei-Chieng Cha Yusuke Nakamura Daniel Levy Masayuki Kimura Shih-Jen Hwang Steven Hunt Tim Spector Nicole Soranzo Ani W Manichaikul R Graham Barr Bratati Kahali Elizabeth Speliotes Laura M Yerges-Armstrong Ching-Yu Cheng Jost B Jonas Tien Yin Wong Isabella Fogh Kuang Lin John F Powell Kenneth Rice Caroline L Relton Richard M Martin George Davey Smith

JAMA Oncol 2017 May;3(5):636-651

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.

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May 2017

seXY: a tool for sex inference from genotype arrays.

Bioinformatics 2017 02;33(4):561-563

Department of Biomedical Data Science, Dartmouth Geisel School of Medicine, Lebanon, NH 03756, USA.

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February 2017

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.

Authors:
Christopher I Amos Joe Dennis Zhaoming Wang Jinyoung Byun Fredrick R Schumacher Simon A Gayther Graham Casey David J Hunter Thomas A Sellers Stephen B Gruber Alison M Dunning Kyriaki Michailidou Laura Fachal Kimberly Doheny Amanda B Spurdle Yafang Li Xiangjun Xiao Jane Romm Elizabeth Pugh Gerhard A Coetzee Dennis J Hazelett Stig E Bojesen Charlisse Caga-Anan Christopher A Haiman Ahsan Kamal Craig Luccarini Daniel Tessier Daniel Vincent François Bacot David J Van Den Berg Stefanie Nelson Stephen Demetriades David E Goldgar Fergus J Couch Judith L Forman Graham G Giles David V Conti Heike Bickeböller Angela Risch Melanie Waldenberger Irene Brüske-Hohlfeld Belynda D Hicks Hua Ling Lesley McGuffog Andrew Lee Karoline Kuchenbaecker Penny Soucy Judith Manz Julie M Cunningham Katja Butterbach Zsofia Kote-Jarai Peter Kraft Liesel FitzGerald Sara Lindström Marcia Adams James D McKay Catherine M Phelan Sara Benlloch Linda E Kelemen Paul Brennan Marjorie Riggan Tracy A O'Mara Hongbing Shen Yongyong Shi Deborah J Thompson Marc T Goodman Sune F Nielsen Andrew Berchuck Sylvie Laboissiere Stephanie L Schmit Tameka Shelford Christopher K Edlund Jack A Taylor John K Field Sue K Park Kenneth Offit Mads Thomassen Rita Schmutzler Laura Ottini Rayjean J Hung Jonathan Marchini Ali Amin Al Olama Ulrike Peters Rosalind A Eeles Michael F Seldin Elizabeth Gillanders Daniela Seminara Antonis C Antoniou Paul D P Pharoah Georgia Chenevix-Trench Stephen J Chanock Jacques Simard Douglas F Easton

Cancer Epidemiol Biomarkers Prev 2017 01 3;26(1):126-135. Epub 2016 Oct 3.

Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, United Kingdom.

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January 2017

Reducing GWAS Complexity.

Cell Cycle 2016 ;15(1):22-4

b Departments of Preventive Medicine and Urology , USC/Norris Cancer Center , USA.

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October 2016

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

Authors:
Gordon Fehringer Peter Kraft Paul D Pharoah Rosalind A Eeles Nilanjan Chatterjee Fredrick R Schumacher Joellen M Schildkraut Sara Lindström Paul Brennan Heike Bickeböller Richard S Houlston Maria Teresa Landi Neil Caporaso Angela Risch Ali Amin Al Olama Sonja I Berndt Edward L Giovannucci Henrik Grönberg Zsofia Kote-Jarai Jing Ma Kenneth Muir Meir J Stampfer Victoria L Stevens Fredrik Wiklund Walter C Willett Ellen L Goode Jennifer B Permuth Harvey A Risch Brett M Reid Stephane Bezieau Hermann Brenner Andrew T Chan Jenny Chang-Claude Thomas J Hudson Jonathan K Kocarnik Polly A Newcomb Robert E Schoen Martha L Slattery Emily White Muriel A Adank Habibul Ahsan Kristiina Aittomäki Laura Baglietto Carl Blomquist Federico Canzian Kamila Czene Isabel Dos-Santos-Silva A Heather Eliassen Jonine D Figueroa Dieter Flesch-Janys Olivia Fletcher Montserrat Garcia-Closas Mia M Gaudet Nichola Johnson Per Hall Aditi Hazra Rebecca Hein Albert Hofman John L Hopper Astrid Irwanto Mattias Johansson Rudolf Kaaks Muhammad G Kibriya Peter Lichtner Jianjun Liu Eiliv Lund Enes Makalic Alfons Meindl Bertram Müller-Myhsok Taru A Muranen Heli Nevanlinna Petra H Peeters Julian Peto Ross L Prentice Nazneen Rahman Maria Jose Sanchez Daniel F Schmidt Rita K Schmutzler Melissa C Southey Rulla Tamimi Ruth C Travis Clare Turnbull Andre G Uitterlinden Zhaoming Wang Alice S Whittemore Xiaohong R Yang Wei Zheng Daniel D Buchanan Graham Casey David V Conti Christopher K Edlund Steven Gallinger Robert W Haile Mark Jenkins Loïc Le Marchand Li Li Noralene M Lindor Stephanie L Schmit Stephen N Thibodeau Michael O Woods Thorunn Rafnar Julius Gudmundsson Simon N Stacey Kari Stefansson Patrick Sulem Y Ann Chen Jonathan P Tyrer David C Christiani Yongyue Wei Hongbing Shen Zhibin Hu Xiao-Ou Shu Kouya Shiraishi Atsushi Takahashi Yohan Bossé Ma'en Obeidat David Nickle Wim Timens Matthew L Freedman Qiyuan Li Daniela Seminara Stephen J Chanock Jian Gong Ulrike Peters Stephen B Gruber Christopher I Amos Thomas A Sellers Douglas F Easton David J Hunter Christopher A Haiman Brian E Henderson Rayjean J Hung

Cancer Res 2016 09 20;76(17):5103-14. Epub 2016 Apr 20.

Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada.

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September 2016

Reply to S. Kilickap et al, Y. Karakas et al, and I.A. Voutsadakis.

J Clin Oncol 2016 Jun 21;34(17):2071-2. Epub 2016 Mar 21.

The Institute of Cancer Research, Sutton, London, United Kingdom.

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June 2016

The PROFILE Feasibility Study: Targeted Screening of Men With a Family History of Prostate Cancer.

Oncologist 2016 06 5;21(6):716-22. Epub 2016 May 5.

Oncogenetics Team, The Institute of Cancer Research, London, United Kingdom Academic Urology Unit, The Royal Marsden National Health Service Foundation Trust, London, United Kingdom

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June 2016

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.

Authors:
Robert A Scott Daniel F Freitag Li Li Audrey Y Chu Praveen Surendran Robin Young Niels Grarup Alena Stancáková Yuning Chen Tibor V Varga Hanieh Yaghootkar Jian'an Luan Jing Hua Zhao Sara M Willems Jennifer Wessel Shuai Wang Nisa Maruthur Kyriaki Michailidou Ailith Pirie Sven J van der Lee Christopher Gillson Ali Amin Al Olama Philippe Amouyel Larraitz Arriola Dominique Arveiler Iciar Aviles-Olmos Beverley Balkau Aurelio Barricarte Inês Barroso Sara Benlloch Garcia Joshua C Bis Stefan Blankenberg Michael Boehnke Heiner Boeing Eric Boerwinkle Ingrid B Borecki Jette Bork-Jensen Sarah Bowden Carlos Caldas Muriel Caslake L Adrienne Cupples Carlos Cruchaga Jacek Czajkowski Marcel den Hoed Janet A Dunn Helena M Earl Georg B Ehret Ele Ferrannini Jean Ferrieres Thomas Foltynie Ian Ford Nita G Forouhi Francesco Gianfagna Carlos Gonzalez Sara Grioni Louise Hiller Jan-Håkan Jansson Marit E Jørgensen J Wouter Jukema Rudolf Kaaks Frank Kee Nicola D Kerrison Timothy J Key Jukka Kontto Zsofia Kote-Jarai Aldi T Kraja Kari Kuulasmaa Johanna Kuusisto Allan Linneberg Chunyu Liu Gaëlle Marenne Karen L Mohlke Andrew P Morris Kenneth Muir Martina Müller-Nurasyid Patricia B Munroe Carmen Navarro Sune F Nielsen Peter M Nilsson Børge G Nordestgaard Chris J Packard Domenico Palli Salvatore Panico Gina M Peloso Markus Perola Annette Peters Christopher J Poole J Ramón Quirós Olov Rolandsson Carlotta Sacerdote Veikko Salomaa María-José Sánchez Naveed Sattar Stephen J Sharp Rebecca Sims Nadia Slimani Jennifer A Smith Deborah J Thompson Stella Trompet Rosario Tumino Daphne L van der A Yvonne T van der Schouw Jarmo Virtamo Mark Walker Klaudia Walter Jean E Abraham Laufey T Amundadottir Jennifer L Aponte Adam S Butterworth Josée Dupuis Douglas F Easton Rosalind A Eeles Jeanette Erdmann Paul W Franks Timothy M Frayling Torben Hansen Joanna M M Howson Torben Jørgensen Jaspal Kooner Markku Laakso Claudia Langenberg Mark I McCarthy James S Pankow Oluf Pedersen Elio Riboli Jerome I Rotter Danish Saleheen Nilesh J Samani Heribert Schunkert Peter Vollenweider Stephen O'Rahilly Panos Deloukas John Danesh Mark O Goodarzi Sekar Kathiresan James B Meigs Margaret G Ehm Nicholas J Wareham Dawn M Waterworth

Sci Transl Med 2016 06;8(341):341ra76

Genetics, PCPS, GlaxoSmithKline, Philadelphia, PA 19104, USA.

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June 2016

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.

Authors:
Alexander Gusev Huwenbo Shi Gleb Kichaev Mark Pomerantz Fugen Li Henry W Long Sue A Ingles Rick A Kittles Sara S Strom Benjamin A Rybicki Barbara Nemesure William B Isaacs Wei Zheng Curtis A Pettaway Edward D Yeboah Yao Tettey Richard B Biritwum Andrew A Adjei Evelyn Tay Ann Truelove Shelley Niwa Anand P Chokkalingam Esther M John Adam B Murphy Lisa B Signorello John Carpten M Cristina Leske Suh-Yuh Wu Anslem J M Hennis Christine Neslund-Dudas Ann W Hsing Lisa Chu Phyllis J Goodman Eric A Klein John S Witte Graham Casey Sam Kaggwa Michael B Cook Daniel O Stram William J Blot Rosalind A Eeles Douglas Easton Zsofia Kote-Jarai Ali Amin Al Olama Sara Benlloch Kenneth Muir Graham G Giles Melissa C Southey Liesel M Fitzgerald Henrik Gronberg Fredrik Wiklund Markus Aly Brian E Henderson Johanna Schleutker Tiina Wahlfors Teuvo L J Tammela Børge G Nordestgaard Tim J Key Ruth C Travis David E Neal Jenny L Donovan Freddie C Hamdy Paul Pharoah Nora Pashayan Kay-Tee Khaw Janet L Stanford Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Christiane Maier Walther Vogel Manuel Luedeke Kathleen Herkommer Adam S Kibel Cezary Cybulski Dominika Wokolorczyk Wojciech Kluzniak Lisa Cannon-Albright Craig Teerlink Hermann Brenner Aida K Dieffenbach Volker Arndt Jong Y Park Thomas A Sellers Hui-Yi Lin Chavdar Slavov Radka Kaneva Vanio Mitev Jyotsna Batra Amanda Spurdle Judith A Clements Manuel R Teixeira Hardev Pandha Agnieszka Michael Paula Paulo Sofia Maia Andrzej Kierzek David V Conti Demetrius Albanes Christine Berg Sonja I Berndt Daniele Campa E David Crawford W Ryan Diver Susan M Gapstur J Michael Gaziano Edward Giovannucci Robert Hoover David J Hunter Mattias Johansson Peter Kraft Loic Le Marchand Sara Lindström Carmen Navarro Kim Overvad Elio Riboli Afshan Siddiq Victoria L Stevens Dimitrios Trichopoulos Paolo Vineis Meredith Yeager Gosia Trynka Soumya Raychaudhuri Frederick R Schumacher Alkes L Price Matthew L Freedman Christopher A Haiman Bogdan Pasaniuc

Nat Commun 2016 Apr 7;7:10979. Epub 2016 Apr 7.

Bioinformatics Interdepartmental Program, University of California Los Angeles, Los Angeles, California 90095, USA.

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April 2016

Risk Analysis of Prostate Cancer in PRACTICAL Consortium--Response.

Cancer Epidemiol Biomarkers Prev 2016 Jan;25(1):223

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.

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January 2016

Prostate cancer screening in BRCA and Lynch syndrome mutation carriers.

Am Soc Clin Oncol Educ Book 2013

From the Prostate and Genitourinary Tumors Unit, Spanish National Cancer Research Centre, Madrid, Spain; Oncogenetics Team, Division of Cancer Genetics and Epidemiology, The Institute of Cancer Research, Sutton, United Kingdom; and the Academic Urology and Cancer Genetics Units, The Royal Marsden NH Foundation Trust, Sutton, United Kingdom.

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December 2015

Adjuvant Hormone Therapy May Improve Survival in Epithelial Ovarian Cancer: Results of the AHT Randomized Trial.

J Clin Oncol 2015 Dec 28;33(35):4138-44. Epub 2015 Sep 28.

Rosalind A. Eeles, James P. Morden, and Judith M. Bliss, The Institute of Cancer Research; Martin Gore, The Royal Marsden Hospital; Janine Mansi, St George's Hospital; Peter Harper, Guy's Hospital, London; John Glees, Epsom Hospital, Epsom, and The Royal Marsden Hospital, Sutton; Christopher Williams, Southampton General Hospital, Southampton; Henry Kitchener, Aberdeen Royal Infirmary, Aberdeen; Richard Osborne, Addenbrookes Hospital, Cambridge; David Guthrie, Derbyshire Royal Infirmary, Derby, United Kingdom; and Miklos Wenczl, Markusovszky Teaching Hospital, Szombathely, Hungary.

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December 2015

Genome-wide association study of prostate cancer-specific survival.

Cancer Epidemiol Biomarkers Prev 2015 Nov 25;24(11):1796-800. Epub 2015 Aug 25.

Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.

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November 2015

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.

Hum Mol Genet 2015 Oct 29;24(19):5589-602. Epub 2015 May 29.

Division of Genetics and Epidemiology, The Institute of Cancer Research & Royal Marsden NHS Foundation Trust, London, UK,

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October 2015

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.

Hum Mol Genet 2015 Oct 10;24(19):5603-18. Epub 2015 Jul 10.

Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center,

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October 2015

Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci.

Cancer Epidemiol Biomarkers Prev 2015 Jul 2;24(7):1121-9. Epub 2015 Apr 2.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, United Kingdom.

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July 2015

Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis.

PLoS One 2014 31;9(10):e110569. Epub 2014 Oct 31.

Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan; Research Center for Genes, Environment and Human Health, College of Public Health, National Taiwan University, Taipei, Taiwan; Department of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan.

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June 2015

Corrigendum to "Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study" [Eur Urol 2014;66:489-99].

Eur Urol 2015 Jun 18;67(6):e126. Epub 2014 Dec 18.

Oncogenetics Team, Institute of Cancer Research, London, UK; Cancer Genetics Unit and Academic Urology Unit, Royal Marsden NHS Foundation Trust, London, UK. Electronic address:

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June 2015

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.

Authors:
Paolo Peterlongo Jenny Chang-Claude Kirsten B Moysich Anja Rudolph Rita K Schmutzler Jacques Simard Penny Soucy Rosalind A Eeles Douglas F Easton Ute Hamann Stefan Wilkening Bowang Chen Matti A Rookus Marjanka K Schmidt Frederieke H van der Baan Amanda B Spurdle Logan C Walker Felicity Lose Ana-Teresa Maia Marco Montagna Laura Matricardi Jan Lubinski Anna Jakubowska Encarna B Gómez Garcia Olufunmilayo I Olopade Robert L Nussbaum Katherine L Nathanson Susan M Domchek Timothy R Rebbeck Banu K Arun Beth Y Karlan Sandra Orsulic Jenny Lester Wendy K Chung Alex Miron Melissa C Southey David E Goldgar Saundra S Buys Ramunas Janavicius Cecilia M Dorfling Elizabeth J van Rensburg Yuan Chun Ding Susan L Neuhausen Thomas V O Hansen Anne-Marie Gerdes Bent Ejlertsen Lars Jønson Ana Osorio Cristina Martínez-Bouzas Javier Benitez Edye E Conway Kathleen R Blazer Jeffrey N Weitzel Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Giulietta Scuvera Monica Barile Filomena Ficarazzi Frederique Mariette Stefano Fortuzzi Alessandra Viel Giuseppe Giannini Laura Papi Aline Martayan Maria Grazia Tibiletti Paolo Radice Athanassios Vratimos Florentia Fostira Judy E Garber Alan Donaldson Carole Brewer Claire Foo D Gareth R Evans Debra Frost Diana Eccles Angela Brady Jackie Cook Marc Tischkowitz Julian Adlard Julian Barwell Lisa Walker Louise Izatt Lucy E Side M John Kennedy Mark T Rogers Mary E Porteous Patrick J Morrison Radka Platte Rosemarie Davidson Shirley V Hodgson Steve Ellis Trevor Cole Andrew K Godwin Kathleen Claes Tom Van Maerken Alfons Meindl Andrea Gehrig Christian Sutter Christoph Engel Dieter Niederacher Doris Steinemann Hansjoerg Plendl Karin Kast Kerstin Rhiem Nina Ditsch Norbert Arnold Raymonda Varon-Mateeva Barbara Wappenschmidt Shan Wang-Gohrke Brigitte Bressac-de Paillerets Bruno Buecher Capucine Delnatte Claude Houdayer Dominique Stoppa-Lyonnet Francesca Damiola Isabelle Coupier Laure Barjhoux Laurence Venat-Bouvet Lisa Golmard Nadia Boutry-Kryza Olga M Sinilnikova Olivier Caron Pascal Pujol Sylvie Mazoyer Muriel Belotti Marion Piedmonte Michael L Friedlander Gustavo C Rodriguez Larry J Copeland Miguel de la Hoya Pedro Perez Segura Heli Nevanlinna Kristiina Aittomäki Theo A M van Os Hanne E J Meijers-Heijboer Annemarie H van der Hout Maaike P G Vreeswijk Nicoline Hoogerbrugge Margreet G E M Ausems Helena C van Doorn J Margriet Collée Edith Olah Orland Diez Ignacio Blanco Conxi Lazaro Joan Brunet Lidia Feliubadalo Cezary Cybulski Jacek Gronwald Katarzyna Durda Katarzyna Jaworska-Bieniek Grzegorz Sukiennicki Adalgeir Arason Jocelyne Chiquette Manuel R Teixeira Curtis Olswold Fergus J Couch Noralane M Lindor Xianshu Wang Csilla I Szabo Kenneth Offit Marina Corines Lauren Jacobs Mark E Robson Liying Zhang Vijai Joseph Andreas Berger Christian F Singer Christine Rappaport Daphne Geschwantler Kaulich Georg Pfeiler Muy-Kheng M Tea Catherine M Phelan Mark H Greene Phuong L Mai Gad Rennert Anna Marie Mulligan Gord Glendon Sandrine Tchatchou Irene L Andrulis Amanda Ewart Toland Anders Bojesen Inge Sokilde Pedersen Mads Thomassen Uffe Birk Jensen Yael Laitman Johanna Rantala Anna von Wachenfeldt Hans Ehrencrona Marie Stenmark Askmalm Åke Borg Karoline B Kuchenbaecker Lesley McGuffog Daniel Barrowdale Sue Healey Andrew Lee Paul D P Pharoah Georgia Chenevix-Trench Antonis C Antoniou Eitan Friedman

Cancer Epidemiol Biomarkers Prev 2015 Jan 21;24(1):308-16. Epub 2014 Oct 21.

Sheba Medical Center, Tel Aviv, Israel.

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January 2015

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.

Authors:
Ali Amin Al Olama Zsofia Kote-Jarai Sonja I Berndt David V Conti Fredrick Schumacher Ying Han Sara Benlloch Dennis J Hazelett Zhaoming Wang Ed Saunders Daniel Leongamornlert Sara Lindstrom Sara Jugurnauth-Little Tokhir Dadaev Malgorzata Tymrakiewicz Daniel O Stram Kristin Rand Peggy Wan Alex Stram Xin Sheng Loreall C Pooler Karen Park Lucy Xia Jonathan Tyrer Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Merideth Yeager Laurie Burdette Charles C Chung Amy Hutchinson Kai Yu Chee Goh Mahbubl Ahmed Koveela Govindasami Michelle Guy Teuvo L J Tammela Anssi Auvinen Tiina Wahlfors Johanna Schleutker Tapio Visakorpi Katri A Leinonen Jianfeng Xu Markus Aly Jenny Donovan Ruth C Travis Tim J Key Afshan Siddiq Federico Canzian Kay-Tee Khaw Atsushi Takahashi Michiaki Kubo Paul Pharoah Nora Pashayan Maren Weischer Borge G Nordestgaard Sune F Nielsen Peter Klarskov Martin Andreas Røder Peter Iversen Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Janet L Stanford Suzanne Kolb Sarah Holt Beatrice Knudsen Antonio Hurtado Coll Susan M Gapstur W Ryan Diver Victoria L Stevens Christiane Maier Manuel Luedeke Kathleen Herkommer Antje E Rinckleb Sara S Strom Curtis Pettaway Edward D Yeboah Yao Tettey Richard B Biritwum Andrew A Adjei Evelyn Tay Ann Truelove Shelley Niwa Anand P Chokkalingam Lisa Cannon-Albright Cezary Cybulski Dominika Wokołorczyk Wojciech Kluźniak Jong Park Thomas Sellers Hui-Yi Lin William B Isaacs Alan W Partin Hermann Brenner Aida Karina Dieffenbach Christa Stegmaier Constance Chen Edward L Giovannucci Jing Ma Meir Stampfer Kathryn L Penney Lorelei Mucci Esther M John Sue A Ingles Rick A Kittles Adam B Murphy Hardev Pandha Agnieszka Michael Andrzej M Kierzek William Blot Lisa B Signorello Wei Zheng Demetrius Albanes Jarmo Virtamo Stephanie Weinstein Barbara Nemesure John Carpten Cristina Leske Suh-Yuh Wu Anselm Hennis Adam S Kibel Benjamin A Rybicki Christine Neslund-Dudas Ann W Hsing Lisa Chu Phyllis J Goodman Eric A Klein S Lilly Zheng Jyotsna Batra Judith Clements Amanda Spurdle Manuel R Teixeira Paula Paulo Sofia Maia Chavdar Slavov Radka Kaneva Vanio Mitev John S Witte Graham Casey Elizabeth M Gillanders Daniella Seminara Elio Riboli Freddie C Hamdy Gerhard A Coetzee Qiyuan Li Matthew L Freedman David J Hunter Kenneth Muir Henrik Gronberg David E Neal Melissa Southey Graham G Giles Gianluca Severi Michael B Cook Hidewaki Nakagawa Fredrik Wiklund Peter Kraft Stephen J Chanock Brian E Henderson Douglas F Easton Rosalind A Eeles Christopher A Haiman

Nat Genet 2014 Oct 14;46(10):1103-9. Epub 2014 Sep 14.

1] Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA. [2] Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA. [3].

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October 2014

Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study.

Authors:
Elizabeth K Bancroft Elizabeth C Page Elena Castro Hans Lilja Andrew Vickers Daniel Sjoberg Melissa Assel Christopher S Foster Gillian Mitchell Kate Drew Lovise Mæhle Karol Axcrona D Gareth Evans Barbara Bulman Diana Eccles Donna McBride Christi van Asperen Hans Vasen Lambertus A Kiemeney Janneke Ringelberg Cezary Cybulski Dominika Wokolorczyk Christina Selkirk Peter J Hulick Anders Bojesen Anne-Bine Skytte Jimmy Lam Louise Taylor Rogier Oldenburg Ruben Cremers Gerald Verhaegh Wendy A van Zelst-Stams Jan C Oosterwijk Ignacio Blanco Monica Salinas Jackie Cook Derek J Rosario Saundra Buys Tom Conner Margreet G Ausems Kai-ren Ong Jonathan Hoffman Susan Domchek Jacquelyn Powers Manuel R Teixeira Sofia Maia William D Foulkes Nassim Taherian Marielle Ruijs Apollonia T Helderman-van den Enden Louise Izatt Rosemarie Davidson Muriel A Adank Lisa Walker Rita Schmutzler Kathy Tucker Judy Kirk Shirley Hodgson Marion Harris Fiona Douglas Geoffrey J Lindeman Janez Zgajnar Marc Tischkowitz Virginia E Clowes Rachel Susman Teresa Ramón y Cajal Nicholas Patcher Neus Gadea Allan Spigelman Theo van Os Annelie Liljegren Lucy Side Carole Brewer Angela F Brady Alan Donaldson Vigdis Stefansdottir Eitan Friedman Rakefet Chen-Shtoyerman David J Amor Lucia Copakova Julian Barwell Veda N Giri Vedang Murthy Nicola Nicolai Soo-Hwang Teo Lynn Greenhalgh Sara Strom Alex Henderson John McGrath David Gallagher Neil Aaronson Audrey Ardern-Jones Chris Bangma David Dearnaley Philandra Costello Jorunn Eyfjord Jeanette Rothwell Alison Falconer Henrik Gronberg Freddie C Hamdy Oskar Johannsson Vincent Khoo Zsofia Kote-Jarai Jan Lubinski Ulrika Axcrona Jane Melia Joanne McKinley Anita V Mitra Clare Moynihan Gad Rennert Mohnish Suri Penny Wilson Emma Killick Sue Moss Rosalind A Eeles

Eur Urol 2014 Sep 15;66(3):489-99. Epub 2014 Jan 15.

Oncogenetics Team, Institute of Cancer Research, London, UK; Cancer Genetics Unit and Academic Urology Unit, Royal Marsden NHS Foundation Trust, London, UK. Electronic address:

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September 2014

Lymphocyte telomere length is long in BRCA1 and BRCA2 mutation carriers regardless of cancer-affected status.

Cancer Epidemiol Biomarkers Prev 2014 Jun 18;23(6):1018-24. Epub 2014 Mar 18.

Authors' Affiliations: Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care; Centre for Cancer Genetic Epidemiology, Department of Oncology, Strangeways Research Laboratory, University of Cambridge; Department of Epigenetics, Babraham Institute, Babraham Research Campus; Department of Medical Genetics, University of Cambridge, Cambridge; South East Thames Regional Genetics Service, Guy's Hospital; North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust; Clinical Genetics Department, St. Georges Hospital, University of London, London; Yorkshire Regional Genetics Service, Leeds; Leicestershire Clinical Genetics Service, University Hospitals of Leicester NHS Trust; Department of Clinical Genetics, Royal Devon & Exeter Hospital, Exeter; West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham;Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield; Ferguson-Smith Centre for Clinical Genetics, Yorkhill Hospitals, Glasgow; South West Regional Genetics Service, Bristol; North West Thames Regional Genetics Service, Kennedy-Galton Centre, Harrow; Institute of Human Genetics, Centre for Life, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle upon Tyne; Nottingham Clinical Genetics Service, Nottingham University Hospitals NHS Trust; Cheshire & Merseyside Clinical Genetics Service, Liverpool Women's NHS Foundation Trust, Liverpool; All Wales Medical Genetics Service, Glan Clwyd Hospital, Rhyl; North of Scotland Regional Genetics Service, NHS Grampian & University of Aberdeen, Foresterhill, Aberdeen; All Wales Medical Genetics Services, Singleton Hospital, Swansea; South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh; All Wales Medical Genetics Services, University Hospital of Wales, Cardiff; Oxford Regional Genetics Service, Churchill Hospital, Oxford; Wessex Clinical Genetics Service, Princess A

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June 2014

Li-Fraumeni syndrome: cancer risk assessment and clinical management.

Nat Rev Clin Oncol 2014 May 18;11(5):260-71. Epub 2014 Mar 18.

The Familial Cancer Centre, Sir Peter MacCallum Department of Oncology, University of Melbourne, Peter MacCallum Cancer Centre, East Melbourne, VIC 3002, Australia.

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May 2014

Comprehensive functional annotation of 77 prostate cancer risk loci.

PLoS Genet 2014 Jan 30;10(1):e1004102. Epub 2014 Jan 30.

Departments of Urology and Preventive Medicine, Norris Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California, United States of America.

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January 2014

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.

Hum Mol Genet 2013 Jun 27;22(12):2520-8. Epub 2013 Mar 27.

The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, UK.

View Article
June 2013

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.

Authors:
Fergus J Couch Xianshu Wang Lesley McGuffog Andrew Lee Curtis Olswold Karoline B Kuchenbaecker Penny Soucy Zachary Fredericksen Daniel Barrowdale Joe Dennis Mia M Gaudet Ed Dicks Matthew Kosel Sue Healey Olga M Sinilnikova Adam Lee François Bacot Daniel Vincent Frans B L Hogervorst Susan Peock Dominique Stoppa-Lyonnet Anna Jakubowska Paolo Radice Rita Katharina Schmutzler Susan M Domchek Marion Piedmonte Christian F Singer Eitan Friedman Mads Thomassen Thomas V O Hansen Susan L Neuhausen Csilla I Szabo Ignacio Blanco Mark H Greene Beth Y Karlan Judy Garber Catherine M Phelan Jeffrey N Weitzel Marco Montagna Edith Olah Irene L Andrulis Andrew K Godwin Drakoulis Yannoukakos David E Goldgar Trinidad Caldes Heli Nevanlinna Ana Osorio Mary Beth Terry Mary B Daly Elizabeth J van Rensburg Ute Hamann Susan J Ramus Amanda Ewart Toland Maria A Caligo Olufunmilayo I Olopade Nadine Tung Kathleen Claes Mary S Beattie Melissa C Southey Evgeny N Imyanitov Marc Tischkowitz Ramunas Janavicius Esther M John Ava Kwong Orland Diez Judith Balmaña Rosa B Barkardottir Banu K Arun Gad Rennert Soo-Hwang Teo Patricia A Ganz Ian Campbell Annemarie H van der Hout Carolien H M van Deurzen Caroline Seynaeve Encarna B Gómez Garcia Flora E van Leeuwen Hanne E J Meijers-Heijboer Johannes J P Gille Margreet G E M Ausems Marinus J Blok Marjolijn J L Ligtenberg Matti A Rookus Peter Devilee Senno Verhoef Theo A M van Os Juul T Wijnen Debra Frost Steve Ellis Elena Fineberg Radka Platte D Gareth Evans Louise Izatt Rosalind A Eeles Julian Adlard Diana M Eccles Jackie Cook Carole Brewer Fiona Douglas Shirley Hodgson Patrick J Morrison Lucy E Side Alan Donaldson Catherine Houghton Mark T Rogers Huw Dorkins Jacqueline Eason Helen Gregory Emma McCann Alex Murray Alain Calender Agnès Hardouin Pascaline Berthet Capucine Delnatte Catherine Nogues Christine Lasset Claude Houdayer Dominique Leroux Etienne Rouleau Fabienne Prieur Francesca Damiola Hagay Sobol Isabelle Coupier Laurence Venat-Bouvet Laurent Castera Marion Gauthier-Villars Mélanie Léoné Pascal Pujol Sylvie Mazoyer Yves-Jean Bignon Elżbieta Złowocka-Perłowska Jacek Gronwald Jan Lubinski Katarzyna Durda Katarzyna Jaworska Tomasz Huzarski Amanda B Spurdle Alessandra Viel Bernard Peissel Bernardo Bonanni Giulia Melloni Laura Ottini Laura Papi Liliana Varesco Maria Grazia Tibiletti Paolo Peterlongo Sara Volorio Siranoush Manoukian Valeria Pensotti Norbert Arnold Christoph Engel Helmut Deissler Dorothea Gadzicki Andrea Gehrig Karin Kast Kerstin Rhiem Alfons Meindl Dieter Niederacher Nina Ditsch Hansjoerg Plendl Sabine Preisler-Adams Stefanie Engert Christian Sutter Raymonda Varon-Mateeva Barbara Wappenschmidt Bernhard H F Weber Brita Arver Marie Stenmark-Askmalm Niklas Loman Richard Rosenquist Zakaria Einbeigi Katherine L Nathanson Timothy R Rebbeck Stephanie V Blank David E Cohn Gustavo C Rodriguez Laurie Small Michael Friedlander Victoria L Bae-Jump Anneliese Fink-Retter Christine Rappaport Daphne Gschwantler-Kaulich Georg Pfeiler Muy-Kheng Tea Noralane M Lindor Bella Kaufman Shani Shimon Paluch Yael Laitman Anne-Bine Skytte Anne-Marie Gerdes Inge Sokilde Pedersen Sanne Traasdahl Moeller Torben A Kruse Uffe Birk Jensen Joseph Vijai Kara Sarrel Mark Robson Noah Kauff Anna Marie Mulligan Gord Glendon Hilmi Ozcelik Bent Ejlertsen Finn C Nielsen Lars Jønson Mette K Andersen Yuan Chun Ding Linda Steele Lenka Foretova Alex Teulé Conxi Lazaro Joan Brunet Miquel Angel Pujana Phuong L Mai Jennifer T Loud Christine Walsh Jenny Lester Sandra Orsulic Steven A Narod Josef Herzog Sharon R Sand Silvia Tognazzo Simona Agata Tibor Vaszko Joellen Weaver Alexandra V Stavropoulou Saundra S Buys Atocha Romero Miguel de la Hoya Kristiina Aittomäki Taru A Muranen Mercedes Duran Wendy K Chung Adriana Lasa Cecilia M Dorfling Alexander Miron Javier Benitez Leigha Senter Dezheng Huo Salina B Chan Anna P Sokolenko Jocelyne Chiquette Laima Tihomirova Tara M Friebel Bjarni A Agnarsson Karen H Lu Flavio Lejbkowicz Paul A James Per Hall Alison M Dunning Daniel Tessier Julie Cunningham Susan L Slager Chen Wang Steven Hart Kristen Stevens Jacques Simard Tomi Pastinen Vernon S Pankratz Kenneth Offit Douglas F Easton Georgia Chenevix-Trench Antonis C Antoniou

PLoS Genet 2013 27;9(3):e1003212. Epub 2013 Mar 27.

Department of Laboratory Medicine and Pathology, and Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.

View Article
June 2013

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.

Authors:
Rosalind A Eeles Ali Amin Al Olama Sara Benlloch Edward J Saunders Daniel A Leongamornlert Malgorzata Tymrakiewicz Maya Ghoussaini Craig Luccarini Joe Dennis Sarah Jugurnauth-Little Tokhir Dadaev David E Neal Freddie C Hamdy Jenny L Donovan Ken Muir Graham G Giles Gianluca Severi Fredrik Wiklund Henrik Gronberg Christopher A Haiman Fredrick Schumacher Brian E Henderson Loic Le Marchand Sara Lindstrom Peter Kraft David J Hunter Susan Gapstur Stephen J Chanock Sonja I Berndt Demetrius Albanes Gerald Andriole Johanna Schleutker Maren Weischer Federico Canzian Elio Riboli Tim J Key Ruth C Travis Daniele Campa Sue A Ingles Esther M John Richard B Hayes Paul D P Pharoah Nora Pashayan Kay-Tee Khaw Janet L Stanford Elaine A Ostrander Lisa B Signorello Stephen N Thibodeau Dan Schaid Christiane Maier Walther Vogel Adam S Kibel Cezary Cybulski Jan Lubinski Lisa Cannon-Albright Hermann Brenner Jong Y Park Radka Kaneva Jyotsna Batra Amanda B Spurdle Judith A Clements Manuel R Teixeira Ed Dicks Andrew Lee Alison M Dunning Caroline Baynes Don Conroy Melanie J Maranian Shahana Ahmed Koveela Govindasami Michelle Guy Rosemary A Wilkinson Emma J Sawyer Angela Morgan David P Dearnaley Alan Horwich Robert A Huddart Vincent S Khoo Christopher C Parker Nicholas J Van As Christopher J Woodhouse Alan Thompson Tim Dudderidge Chris Ogden Colin S Cooper Artitaya Lophatananon Angela Cox Melissa C Southey John L Hopper Dallas R English Markus Aly Jan Adolfsson Jiangfeng Xu Siqun L Zheng Meredith Yeager Rudolf Kaaks W Ryan Diver Mia M Gaudet Mariana C Stern Roman Corral Amit D Joshi Ahva Shahabi Tiina Wahlfors Teuvo L J Tammela Anssi Auvinen Jarmo Virtamo Peter Klarskov Børge G Nordestgaard M Andreas Røder Sune F Nielsen Stig E Bojesen Afshan Siddiq Liesel M Fitzgerald Suzanne Kolb Erika M Kwon Danielle M Karyadi William J Blot Wei Zheng Qiuyin Cai Shannon K McDonnell Antje E Rinckleb Bettina Drake Graham Colditz Dominika Wokolorczyk Robert A Stephenson Craig Teerlink Heiko Muller Dietrich Rothenbacher Thomas A Sellers Hui-Yi Lin Chavdar Slavov Vanio Mitev Felicity Lose Srilakshmi Srinivasan Sofia Maia Paula Paulo Ethan Lange Kathleen A Cooney Antonis C Antoniou Daniel Vincent François Bacot Daniel C Tessier Zsofia Kote-Jarai Douglas F Easton

Nat Genet 2013 Apr;45(4):385-91, 391e1-2

The Institute of Cancer Research, Sutton, UK.

View Article
April 2013

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.

Authors:
Ali Amin Al Olama Zsofia Kote-Jarai Fredrick R Schumacher Fredrik Wiklund Sonja I Berndt Sara Benlloch Graham G Giles Gianluca Severi David E Neal Freddie C Hamdy Jenny L Donovan David J Hunter Brian E Henderson Michael J Thun Michael Gaziano Edward L Giovannucci Afshan Siddiq Ruth C Travis David G Cox Federico Canzian Elio Riboli Timothy J Key Gerald Andriole Demetrius Albanes Richard B Hayes Johanna Schleutker Anssi Auvinen Teuvo L J Tammela Maren Weischer Janet L Stanford Elaine A Ostrander Cezary Cybulski Jan Lubinski Stephen N Thibodeau Daniel J Schaid Karina D Sorensen Jyotsna Batra Judith A Clements Suzanne Chambers Joanne Aitken Robert A Gardiner Christiane Maier Walther Vogel Thilo Dörk Hermann Brenner Tomonori Habuchi Sue Ingles Esther M John Joanne L Dickinson Lisa Cannon-Albright Manuel R Teixeira Radka Kaneva Hong-Wei Zhang Yong-Jie Lu Jong Y Park Kathleen A Cooney Kenneth R Muir Daniel A Leongamornlert Edward Saunders Malgorzata Tymrakiewicz Nadiya Mahmud Michelle Guy Koveela Govindasami Lynne T O'Brien Rosemary A Wilkinson Amanda L Hall Emma J Sawyer Tokhir Dadaev Jonathan Morrison David P Dearnaley Alan Horwich Robert A Huddart Vincent S Khoo Christopher C Parker Nicholas Van As Christopher J Woodhouse Alan Thompson Tim Dudderidge Chris Ogden Colin S Cooper Artitaya Lophatonanon Melissa C Southey John L Hopper Dallas English Jarmo Virtamo Loic Le Marchand Daniele Campa Rudolf Kaaks Sara Lindstrom W Ryan Diver Susan Gapstur Meredith Yeager Angela Cox Mariana C Stern Roman Corral Markus Aly William Isaacs Jan Adolfsson Jianfeng Xu S Lilly Zheng Tiina Wahlfors Kimmo Taari Paula Kujala Peter Klarskov Børge G Nordestgaard M Andreas Røder Ruth Frikke-Schmidt Stig E Bojesen Liesel M FitzGerald Suzanne Kolb Erika M Kwon Danielle M Karyadi Torben Falck Orntoft Michael Borre Antje Rinckleb Manuel Luedeke Kathleen Herkommer Andreas Meyer Jürgen Serth James R Marthick Briony Patterson Dominika Wokolorczyk Amanda Spurdle Felicity Lose Shannon K McDonnell Amit D Joshi Ahva Shahabi Pedro Pinto Joana Santos Ana Ray Thomas A Sellers Hui-Yi Lin Robert A Stephenson Craig Teerlink Heiko Muller Dietrich Rothenbacher Norihiko Tsuchiya Shintaro Narita Guang-Wen Cao Chavdar Slavov Vanio Mitev Stephen Chanock Henrik Gronberg Christopher A Haiman Peter Kraft Douglas F Easton Rosalind A Eeles

Hum Mol Genet 2013 Jan 12;22(2):408-15. Epub 2012 Oct 12.

Strangeways Laboratory, Centre for Cancer Genetic Epidemiology, Worts Causeway, Cambridge CB1 8RN, UK.

View Article
January 2013

Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk.

Cancer Epidemiol Biomarkers Prev 2012 Jul 27;21(7):1156-66. Epub 2012 Mar 27.

Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

View Article
July 2012

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.

Authors:
Fergus J Couch Mia M Gaudet Antonis C Antoniou Susan J Ramus Karoline B Kuchenbaecker Penny Soucy Jonathan Beesley Xiaoqing Chen Xianshu Wang Tomas Kirchhoff Lesley McGuffog Daniel Barrowdale Andrew Lee Sue Healey Olga M Sinilnikova Irene L Andrulis Hilmi Ozcelik Anna Marie Mulligan Mads Thomassen Anne-Marie Gerdes Uffe Birk Jensen Anne-Bine Skytte Torben A Kruse Maria A Caligo Anna von Wachenfeldt Gisela Barbany-Bustinza Niklas Loman Maria Soller Hans Ehrencrona Per Karlsson Katherine L Nathanson Timothy R Rebbeck Susan M Domchek Ania Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Elzbieta Zlowocka Tomasz Huzarski Tomasz Byrski Jacek Gronwald Cezary Cybulski Bohdan Górski Ana Osorio Mercedes Durán María Isabel Tejada Javier Benitez Ute Hamann Frans B L Hogervorst Theo A van Os Flora E van Leeuwen Hanne E J Meijers-Heijboer Juul Wijnen Marinus J Blok Marleen Kets Maartje J Hooning Rogier A Oldenburg Margreet G E M Ausems Susan Peock Debra Frost Steve D Ellis Radka Platte Elena Fineberg D Gareth Evans Chris Jacobs Rosalind A Eeles Julian Adlard Rosemarie Davidson Diana M Eccles Trevor Cole Jackie Cook Joan Paterson Carole Brewer Fiona Douglas Shirley V Hodgson Patrick J Morrison Lisa Walker Mary E Porteous M John Kennedy Lucy E Side Betsy Bove Andrew K Godwin Dominique Stoppa-Lyonnet Marion Fassy-Colcombet Laurent Castera François Cornelis Sylvie Mazoyer Mélanie Léoné Nadia Boutry-Kryza Brigitte Bressac-de Paillerets Olivier Caron Pascal Pujol Isabelle Coupier Capucine Delnatte Linda Akloul Henry T Lynch Carrie L Snyder Saundra S Buys Mary B Daly Marybeth Terry Wendy K Chung Esther M John Alexander Miron Melissa C Southey John L Hopper David E Goldgar Christian F Singer Christine Rappaport Muy-Kheng M Tea Anneliese Fink-Retter Thomas V O Hansen Finn C Nielsen Aðalgeir Arason Joseph Vijai Sohela Shah Kara Sarrel Mark E Robson Marion Piedmonte Kelly Phillips Jack Basil Wendy S Rubinstein John Boggess Katie Wakeley Amanda Ewart-Toland Marco Montagna Simona Agata Evgeny N Imyanitov Claudine Isaacs Ramunas Janavicius Conxi Lazaro Ignacio Blanco Lidia Feliubadalo Joan Brunet Simon A Gayther Paul P D Pharoah Kunle O Odunsi Beth Y Karlan Christine S Walsh Edith Olah Soo Hwang Teo Patricia A Ganz Mary S Beattie Elizabeth J van Rensburg Cecelia M Dorfling Orland Diez Ava Kwong Rita K Schmutzler Barbara Wappenschmidt Christoph Engel Alfons Meindl Nina Ditsch Norbert Arnold Simone Heidemann Dieter Niederacher Sabine Preisler-Adams Dorothea Gadzicki Raymonda Varon-Mateeva Helmut Deissler Andrea Gehrig Christian Sutter Karin Kast Britta Fiebig Wolfram Heinritz Trinidad Caldes Miguel de la Hoya Taru A Muranen Heli Nevanlinna Marc D Tischkowitz Amanda B Spurdle Susan L Neuhausen Yuan Chun Ding Noralane M Lindor Zachary Fredericksen V Shane Pankratz Paolo Peterlongo Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Monica Barile Loris Bernard Alessandra Viel Giuseppe Giannini Liliana Varesco Paolo Radice Mark H Greene Phuong L Mai Douglas F Easton Georgia Chenevix-Trench Kenneth Offit Jacques Simard

Cancer Epidemiol Biomarkers Prev 2012 Apr 20;21(4):645-57. Epub 2012 Feb 20.

Departments of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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April 2012

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study.

Authors:
Zsofia Kote-Jarai Ali Amin Al Olama Graham G Giles Gianluca Severi Johanna Schleutker Maren Weischer Daniele Campa Elio Riboli Tim Key Henrik Gronberg David J Hunter Peter Kraft Michael J Thun Sue Ingles Stephen Chanock Demetrius Albanes Richard B Hayes David E Neal Freddie C Hamdy Jenny L Donovan Paul Pharoah Fredrick Schumacher Brian E Henderson Janet L Stanford Elaine A Ostrander Karina Dalsgaard Sorensen Thilo Dörk Gerald Andriole Joanne L Dickinson Cezary Cybulski Jan Lubinski Amanda Spurdle Judith A Clements Suzanne Chambers Joanne Aitken R A Frank Gardiner Stephen N Thibodeau Dan Schaid Esther M John Christiane Maier Walther Vogel Kathleen A Cooney Jong Y Park Lisa Cannon-Albright Hermann Brenner Tomonori Habuchi Hong-Wei Zhang Yong-Jie Lu Radka Kaneva Ken Muir Sara Benlloch Daniel A Leongamornlert Edward J Saunders Malgorzata Tymrakiewicz Nadiya Mahmud Michelle Guy Lynne T O'Brien Rosemary A Wilkinson Amanda L Hall Emma J Sawyer Tokhir Dadaev Jonathan Morrison David P Dearnaley Alan Horwich Robert A Huddart Vincent S Khoo Christopher C Parker Nicholas Van As Christopher J Woodhouse Alan Thompson Tim Christmas Chris Ogden Colin S Cooper Aritaya Lophatonanon Melissa C Southey John L Hopper Dallas R English Tiina Wahlfors Teuvo L J Tammela Peter Klarskov Børge G Nordestgaard M Andreas Røder Anne Tybjærg-Hansen Stig E Bojesen Ruth Travis Federico Canzian Rudolf Kaaks Fredrik Wiklund Markus Aly Sara Lindstrom W Ryan Diver Susan Gapstur Mariana C Stern Roman Corral Jarmo Virtamo Angela Cox Christopher A Haiman Loic Le Marchand Liesel Fitzgerald Suzanne Kolb Erika M Kwon Danielle M Karyadi Torben Falck Orntoft Michael Borre Andreas Meyer Jürgen Serth Meredith Yeager Sonja I Berndt James R Marthick Briony Patterson Dominika Wokolorczyk Jyotsna Batra Felicity Lose Shannon K McDonnell Amit D Joshi Ahva Shahabi Antje E Rinckleb Ana Ray Thomas A Sellers Hui-Yi Lin Robert A Stephenson James Farnham Heiko Muller Dietrich Rothenbacher Norihiko Tsuchiya Shintaro Narita Guang-Wen Cao Chavdar Slavov Vanio Mitev Douglas F Easton Rosalind A Eeles

Nat Genet 2011 Jul 10;43(8):785-91. Epub 2011 Jul 10.

The Institute of Cancer Research, Sutton, Surrey, UK.

View Article
July 2011

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.

Authors:
Rosalind A Eeles Zsofia Kote-Jarai Ali Amin Al Olama Graham G Giles Michelle Guy Gianluca Severi Kenneth Muir John L Hopper Brian E Henderson Christopher A Haiman Johanna Schleutker Freddie C Hamdy David E Neal Jenny L Donovan Janet L Stanford Elaine A Ostrander Sue A Ingles Esther M John Stephen N Thibodeau Daniel Schaid Jong Y Park Amanda Spurdle Judith Clements Joanne L Dickinson Christiane Maier Walther Vogel Thilo Dörk Timothy R Rebbeck Kathleen A Cooney Lisa Cannon-Albright Pierre O Chappuis Pierre Hutter Maurice Zeegers Radka Kaneva Hong-Wei Zhang Yong-Jie Lu William D Foulkes Dallas R English Daniel A Leongamornlert Malgorzata Tymrakiewicz Jonathan Morrison Audrey T Ardern-Jones Amanda L Hall Lynne T O'Brien Rosemary A Wilkinson Edward J Saunders Elizabeth C Page Emma J Sawyer Stephen M Edwards David P Dearnaley Alan Horwich Robert A Huddart Vincent S Khoo Christopher C Parker Nicholas Van As Christopher J Woodhouse Alan Thompson Tim Christmas Chris Ogden Colin S Cooper Melissa C Southey Artitaya Lophatananon Jo-Fen Liu Laurence N Kolonel Loic Le Marchand Tiina Wahlfors Teuvo L Tammela Anssi Auvinen Sarah J Lewis Angela Cox Liesel M FitzGerald Joseph S Koopmeiners Danielle M Karyadi Erika M Kwon Mariana C Stern Roman Corral Amit D Joshi Ahva Shahabi Shannon K McDonnell Thomas A Sellers Julio Pow-Sang Suzanne Chambers Joanne Aitken R A Frank Gardiner Jyotsna Batra Mary Anne Kedda Felicity Lose Andrea Polanowski Briony Patterson Jürgen Serth Andreas Meyer Manuel Luedeke Klara Stefflova Anna M Ray Ethan M Lange Jim Farnham Humera Khan Chavdar Slavov Atanaska Mitkova Guangwen Cao Douglas F Easton

Nat Genet 2009 Oct 20;41(10):1116-21. Epub 2009 Sep 20.

The Institute of Cancer Research, Sutton, Surrey, UK.

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October 2009

Genome-wide association studies in cancer.

Hum Mol Genet 2008 Oct;17(R2):R109-15

Cancer Research UK Genetic Epidemiology Unit, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK.

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October 2008

A review of targeted screening for prostate cancer: introducing the IMPACT study.

BJU Int 2007 Jun 5;99(6):1350-5. Epub 2007 Apr 5.

Cancer Genetics, Institute of Cancer Research and Royal Marsden Hospital, London, UK.

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June 2007