Publications by authors named "Rosa Noguera"

100Publications

Imbalance between genomic gain and loss identifies high-risk neuroblastoma patients with worse outcomes.

Neoplasia 2020 Nov 12;23(1):12-20. Epub 2020 Nov 12.

Pathology Department, Medical School, University of Valencia-INCLIVA, Valencia, Spain; CIBERONC, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2020.11.001DOI Listing
November 2020

Potential Molecular Players of the Tumor Microenvironment in Extracranial Pediatric Solid Tumors.

Cancers (Basel) 2020 Oct 9;12(10). Epub 2020 Oct 9.

Low Prevalence Tumors, Center for Biomedical Research in Cancer Network (CIBERONC), Carlos III Health Institute, 28029 Madrid, Spain.

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http://dx.doi.org/10.3390/cancers12102905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600141PMC
October 2020

Integrating the Tumor Microenvironment into Cancer Therapy.

Cancers (Basel) 2020 Jun 24;12(6). Epub 2020 Jun 24.

Low Prevalence Tumors, Centro de investigación biomédica en red de cáncer (CIBERONC), Instituto de Salud Carlos III, 28029 Madrid, Spain.

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http://dx.doi.org/10.3390/cancers12061677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352326PMC
June 2020

[An integral view of cancer (III). Evaluation of new biomarkers and treatment strategies].

Rev Esp Patol 2020 Apr - Jun;53(2):88-99. Epub 2019 Nov 22.

CIBERONC, Madrid, España; Servicio de Anatomía Patológica, Hospital Verge de la Cinta, Tortosa, Tarragona, España. Electronic address:

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http://dx.doi.org/10.1016/j.patol.2019.08.001DOI Listing
November 2019

[An integral view of cancer (II). Fields of investigation and emerging biomarkers].

Rev Esp Patol 2019 Oct - Dec;52(4):222-233. Epub 2019 Jun 11.

CIBERONC, Madrid, España; Servicio de Anatomía Patólogica, Hospital Verge de la Cinta, Tortosa, Tarragona, España. Electronic address:

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http://dx.doi.org/10.1016/j.patol.2019.04.005DOI Listing
June 2020

The tumour microenvironment as an integrated framework to understand cancer biology.

Cancer Lett 2019 Oct 17;461:112-122. Epub 2019 Jul 17.

Departament of Pathology, Medical School, University of Valencia - INCLIVA Biomedical Health Research Institute, Valencia, Spain; CIBERONC, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.07.010DOI Listing
October 2019

The topology of vitronectin: A complementary feature for neuroblastoma risk classification based on computer-aided detection.

Int J Cancer 2020 01 8;146(2):553-565. Epub 2019 Jul 8.

Departamento de Biología Celular, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Roció/CSIC/Universidad de Sevilla, Seville, Spain.

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http://dx.doi.org/10.1002/ijc.32495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899647PMC
January 2020

Vitronectin as a molecular player of the tumor microenvironment in neuroblastoma.

BMC Cancer 2019 May 22;19(1):479. Epub 2019 May 22.

Pathology Department, Medical School, University of Valencia-INCLIVA, Valencia, Spain.

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http://dx.doi.org/10.1186/s12885-019-5693-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532218PMC
May 2019

[An integral view of cancer (I). The study, classification and reprogramming of the tumoral microclimate].

Rev Esp Patol 2019 Apr - Jun;52(2):92-102. Epub 2019 Feb 10.

CIBERONC, Madrid, España; Hospital Verge de la Cinta, Tortosa, Tarragona, España. Electronic address:

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http://dx.doi.org/10.1016/j.patol.2018.11.003DOI Listing
May 2020

Therapeutic Opportunities in Neuroblastoma Using Nanotechnology.

J Pharmacol Exp Ther 2019 09 11;370(3):625-635. Epub 2019 Jan 11.

Pharmacy and Pharmaceutical Technology Department, University of Navarra (C.R.-N., M.J.B.-P.), and Instituto de Investigación Sanitaria de Navarra (IdiSNA) (C.R.-N., M.J.B.-P.), Pamplona, Pathology Department, Medical School, University of Valencia-INCLIVA, Valencia (R.N.), and Cancer CIBER (CIBERONC), Madrid (R.N.), Spain; and Institut Galien Paris-Sud, UMR, Université Paris-Sud, Université Paris-Saclay, Châtenay-Malabry Cedex, France (P.C.)

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http://jpet.aspetjournals.org/lookup/doi/10.1124/jpet.118.25
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http://dx.doi.org/10.1124/jpet.118.255067DOI Listing
September 2019

High Oct4 expression: implications in the pathogenesis of neuroblastic tumours.

BMC Cancer 2019 Jan 3;19(1). Epub 2019 Jan 3.

Pathology Department, Medical School, University of Valencia-INCLIVA, Av. Blasco Ibáñez, 15, 46010, Valencia, Spain.

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http://dx.doi.org/10.1186/s12885-018-5219-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318846PMC
January 2019

Lymph microvascularization as a prognostic indicator in neuroblastoma.

Oncotarget 2018 May 25;9(40):26157-26170. Epub 2018 May 25.

Pathology Department, Medical School, University of Valencia-INCLIVA, Valencia, Spain.

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http://dx.doi.org/10.18632/oncotarget.25457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995242PMC
May 2018

Congenital undifferentiated sarcoma associated to BCOR-CCNB3 gene fusion.

Pathol Res Pract 2017 Nov 14;213(11):1435-1439. Epub 2017 Jul 14.

Department of Pathology, University Clinic Hospital of Valencia, Spain; Department of Pathology, Medical School of Valencia, University of Valencia - INCLIVA, Spain; Ciberonc, Madrid, Spain.

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http://dx.doi.org/10.1016/j.prp.2017.07.012DOI Listing
November 2017

A stiff extracellular matrix is associated with malignancy in peripheral neuroblastic tumors.

Pediatr Blood Cancer 2017 Sep 25;64(9). Epub 2017 Jan 25.

Pathology Department, Medical School, University of Valencia-INCLIVA, Valencia, Spain.

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http://dx.doi.org/10.1002/pbc.26449DOI Listing
September 2017

Extracellular matrix composition defines an ultra-high-risk group of neuroblastoma within the high-risk patient cohort.

Br J Cancer 2016 08 14;115(4):480-9. Epub 2016 Jul 14.

Department of Pathology, Medical School, University of Valencia - INCLIVA, Avda. Blasco Ibañez 15, 46010 Valencia, Spain.

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http://dx.doi.org/10.1038/bjc.2016.210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985353PMC
August 2016

Diagnostic implications of intrapatient genetic tumor heterogeneity.

Mol Cell Oncol 2016 Mar 11;3(2):e1079671. Epub 2015 Sep 11.

Pathology Department, Medical School, University of Valencia, INCLIVA Institute , Valencia, Spain.

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http://dx.doi.org/10.1080/23723556.2015.1079671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905381PMC
March 2016

Genetic features of neuroblastic tumors associated with opsoclonus-myoclonus syndrome opens up the possibility for detection in peripheral blood.

Expert Rev Neurother 2016 05 6;16(5):465-7. Epub 2016 Apr 6.

a Pathology Department , Medical School, University of Valencia, INCLIVA , Valencia , Spain.

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http://dx.doi.org/10.1586/14737175.2016.1163221DOI Listing
May 2016

Two independent epigenetic biomarkers predict survival in neuroblastoma.

Clin Epigenetics 2015 27;7:16. Epub 2015 Feb 27.

Pediatric Oncology Unit, Hospital Universitari i Politècnic La Fe, Avda Fernando Abril Martorell, Valencia, 46026 Spain.

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http://dx.doi.org/10.1186/s13148-015-0054-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357365PMC
March 2015

Individual patient risk stratification of high-risk neuroblastomas using a two-gene score suited for clinical use.

Int J Cancer 2015 Aug 20;137(4):868-77. Epub 2015 Feb 20.

Translational Cancer Research, Department of Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1002/ijc.29461DOI Listing
August 2015

Intragenic anaplastic lymphoma kinase (ALK) rearrangements: translocations as a novel mechanism of ALK activation in neuroblastoma tumors.

Genes Chromosomes Cancer 2015 Feb 23;54(2):99-109. Epub 2014 Sep 23.

Department of Medical and Clinical Genetics, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/gcc.22223DOI Listing
February 2015

Glycosaminoglycan profiling in different cell types using infrared spectroscopy and imaging.

Anal Bioanal Chem 2014 Sep 15;406(24):5795-803. Epub 2014 Jul 15.

Laboratoire de Biochimie médicale et de Biologie Moléculaire, UFR de Médecine, Université de Reims Champagne-Ardenne, 51 rue Cognacq-Jay, 51095, Reims Cedex, France.

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http://link.springer.com/content/pdf/10.1007/s00216-014-7994
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http://link.springer.com/10.1007/s00216-014-7994-2
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http://dx.doi.org/10.1007/s00216-014-7994-2DOI Listing
September 2014

TMA vessel segmentation based on color and morphological features: application to angiogenesis research.

ScientificWorldJournal 2013 5;2013:263190. Epub 2013 Dec 5.

Departmento de Anatomía Patológica, Hospital General Universitario de Ciudad Real, 13005 Ciudad Real, Spain.

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http://dx.doi.org/10.1155/2013/263190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893865PMC
June 2014

Quantitative modeling of clinical, cellular, and extracellular matrix variables suggest prognostic indicators in cancer: a model in neuroblastoma.

Pediatr Res 2014 Feb 11;75(2):302-14. Epub 2013 Nov 11.

Pathology Department, Medical School, University of Valencia, Valencia, Spain.

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http://dx.doi.org/10.1038/pr.2013.217DOI Listing
February 2014

snoRNPs Regulate Telomerase Activity in Neuroblastoma and Are Associated with Poor Prognosis.

Transl Oncol 2013 Aug 1;6(4):447-57. Epub 2013 Aug 1.

Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, Skåne University Hospital, Malmö, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730020PMC
http://dx.doi.org/10.1593/tlo.13112DOI Listing
August 2013

New prognostic markers in neuroblastoma.

Expert Opin Med Diagn 2012 Nov 11;6(6):555-67. Epub 2012 Jul 11.

Department of Pathology, Medical School, University of Valencia , Avda. Blasco Ibañez 15 Valencia 46010 , Spain +34 96 3864146 ; +34 96 3864173 ;

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http://dx.doi.org/10.1517/17530059.2012.704018DOI Listing
November 2012

NeuPAT: an intranet database supporting translational research in neuroblastic tumors.

Comput Biol Med 2013 Mar 4;43(3):219-28. Epub 2013 Jan 4.

Department of Pathology, Medical School, University of Valencia, and Research Foundation of Hospital Clínico Universitario of Valencia, Valencia 46010, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S00104825120019
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http://dx.doi.org/10.1016/j.compbiomed.2012.11.011DOI Listing
March 2013

Pleomorphic hyalinizing angiectatic tumor: a report of 3 new cases, 1 with sarcomatous myxofibrosarcoma component and another with unreported soft tissue palpebral location.

Appl Immunohistochem Mol Morphol 2012 Jan;20(1):96-101

Department of Pathology, Instituto Valenciano de Oncología, Valencia University, Valencia, Spain.

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http://dx.doi.org/10.1097/PAI.0b013e31821a24abDOI Listing
January 2012

Minimal disease detection in peripheral blood and bone marrow from patients with non-metastatic neuroblastoma.

J Cancer Res Clin Oncol 2011 Aug 25;137(8):1263-72. Epub 2011 Jun 25.

Unidad de Oncología Pediátrica, Hospital Universitario y Politécnico La Fe, Bulevar Sur S/N, 46026 Valencia, Spain.

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http://link.springer.com/10.1007/s00432-011-0997-x
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http://dx.doi.org/10.1007/s00432-011-0997-xDOI Listing
August 2011

Prognostic value of partial genetic instability in neuroblastoma with ≤50% neuroblastic cell content.

Histopathology 2011 Jul 13;59(1):22-30. Epub 2011 Jun 13.

Department of Pathology, Medical School, University of Valencia, Spain.

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http://dx.doi.org/10.1111/j.1365-2559.2011.03899.xDOI Listing
July 2011

Alternative lengthening of telomeres--an enhanced chromosomal instability in aggressive non-MYCN amplified and telomere elongated neuroblastomas.

Genes Chromosomes Cancer 2011 Apr 14;50(4):250-62. Epub 2011 Jan 14.

Department of Clinical Genetics, Lund University, University and Regional Laboratories, Skåne University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1002/gcc.20850DOI Listing
April 2011

The epithelial mesenchymal transition process in wilms tumor: a study based on a xenograft model.

Appl Immunohistochem Mol Morphol 2011 Jul;19(4):369-75

Department of Pathology, Medical School, University of Valencia, Valencia, Spain.

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http://dx.doi.org/10.1097/PAI.0b013e31820287a7DOI Listing
July 2011

The many faces of atypical Ewing's sarcoma. A true entity mimicking sarcomas, carcinomas and lymphomas.

Virchows Arch 2011 Mar 23;458(3):281-90. Epub 2010 Dec 23.

Pathology Department, Medical School, Valencia University, Avda Blasco Ibáñez, 15, Valencia, 46010, Spain.

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http://dx.doi.org/10.1007/s00428-010-1023-4DOI Listing
March 2011

Hypermethylation of apoptotic genes as independent prognostic factor in neuroblastoma disease.

Mol Carcinog 2011 Mar 23;50(3):153-62. Epub 2010 Nov 23.

Unidad de Genética y Diagnóstico Prenatal, Hospital Universitario La Fe, Valencia, Spain.

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http://dx.doi.org/10.1002/mc.20700DOI Listing
March 2011

Gain of MYCN region in a Wilms tumor-derived xenotransplanted cell line.

Diagn Mol Pathol 2010 Mar;19(1):33-9

Department of Pathology, University of Valencia, Blasco Ibañez 17, Valencia, Spain.

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https://insights.ovid.com/crossref?an=00019606-201003000-000
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http://dx.doi.org/10.1097/PDM.0b013e3181b11a9dDOI Listing
March 2010

Neuroblastoma in adolescents: genetic and clinical characterisation.

Clin Transl Oncol 2010 Jan;12(1):49-54

Unidad de Oncología Pediátrica, Hospital Universitario La Fe, Valencia, Spain.

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http://dx.doi.org/10.1007/s12094-010-0466-zDOI Listing
January 2010

HIF-2alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells.

Proc Natl Acad Sci U S A 2009 Sep 16;106(39):16805-10. Epub 2009 Sep 16.

Department of Laboratory Medicine, Center for Molecular Pathology, CREATE Health, University Hospital MAS, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1073/pnas.0904606106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745331PMC
September 2009

Immunohistochemical study as a tool in differential diagnosis of pediatric malignant rhabdoid tumor.

Appl Immunohistochem Mol Morphol 2010 Mar;18(2):150-8

Department of Pathology, University of Valencia and University Clinic Hospital, Valencia, Spain.

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http://dx.doi.org/10.1097/PAI.0b013e3181b91a51DOI Listing
March 2010

Aberrant copy numbers of ALK gene is a frequent genetic alteration in neuroblastomas.

Hum Pathol 2009 Nov 5;40(11):1638-42. Epub 2009 Aug 5.

Department of Pathology, Medical School, University of Valencia, 46010 Valencia, Spain.

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http://dx.doi.org/10.1016/j.humpath.2009.05.002DOI Listing
November 2009

New approaches in the diagnosis of small-cell round tumors of bone and soft tissue.

Arkh Patol 2009 Jan-Feb;71(1):34-40

Department of Pathology, Kazan Cancer Center, Kazan 420029, Russia.

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July 2009

HIF-1alpha induces MXI1 by alternate promoter usage in human neuroblastoma cells.

Exp Cell Res 2009 Jul 27;315(11):1924-36. Epub 2009 Feb 27.

Center for Molecular Pathology, Department of Laboratory Medicine, Lund University, University Hospital MAS, Entrance 78, S-20502 Malmö, Sweden.

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http://dx.doi.org/10.1016/j.yexcr.2009.02.015DOI Listing
July 2009

Analysis of biological prognostic factors using tissue microarrays in neuroblastic tumors.

Pediatr Blood Cancer 2009 Feb;52(2):209-14

Department of Pathology, Medical School, University of Valencia, Valencia, Spain.

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http://dx.doi.org/10.1002/pbc.21833DOI Listing
February 2009

Comparison of different techniques for the detection of genetic risk-identifying chromosomal gains and losses in neuroblastoma.

Virchows Arch 2008 Jul 24;453(1):47-55. Epub 2008 Jun 24.

Department of Pathology, Medical School, University of Valencia, Avda/Blasco Ibáñez, 17, Valencia, Spain.

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http://dx.doi.org/10.1007/s00428-008-0633-6DOI Listing
July 2008

GIST: particular aspects related to cell cultures, xenografts, and cytogenetics.

Semin Diagn Pathol 2006 May;23(2):103-10

Unit of Molecular Biology, Fundación Instituto Valenciano de Oncología, Valencia, Spain.

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http://dx.doi.org/10.1053/j.semdp.2006.08.004DOI Listing
May 2006

Evaluation of genetic stability of the SYT gene rearrangement by break-apart FISH in primary and xenotransplanted synovial sarcomas.

Cancer Genet Cytogenet 2007 Jan;172(1):23-8

Department of Pathology, Medical School, University of Valencia, Avda. Blasco Ibañez, 17, 46010 Valencia, Spain.

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http://dx.doi.org/10.1016/j.cancergencyto.2006.07.008DOI Listing
January 2007

p16INK4A (CDKN2A) gene deletion is a frequent genetic event in synovial sarcomas.

Am J Clin Pathol 2006 Dec;126(6):866-74

Department of Pathology, Medical School, University of Valencia, Spain.

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http://dx.doi.org/10.1309/E2AAY2XXN431WL81DOI Listing
December 2006

Comparative effects of estradiol, raloxifene, and genistein on the uterus of ovariectomized mice.

Fertil Steril 2006 Oct 11;86(4):1003-5. Epub 2006 Sep 11.

Research Unit, Hospital Clínico Universitario of Valencia, Valencia, Spain.

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http://dx.doi.org/10.1016/j.fertnstert.2006.03.029DOI Listing
October 2006

Prognostic value of the International Neuroblastoma Pathology Classification in Neuroblastoma (Schwannian stroma-poor) and comparison with other prognostic factors: a study of 182 cases from the Spanish Neuroblastoma Registry.

Virchows Arch 2006 Oct 29;449(4):410-20. Epub 2006 Aug 29.

Departamento de Patología, Facultad de Medicina de Valencia, Avda. Blasco Ibañez, 17, E-46010, Pediatric Oncology Unit, Hospital Universitario La Fe, Valencia, Spain.

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http://dx.doi.org/10.1007/s00428-006-0253-yDOI Listing
October 2006

[Neuroblastoma].

Clin Transl Oncol 2005 Apr;7(3):133-45

Pediatric Oncology Unit, Hospital Infantil La Fe, Avda. Campanar 21, 48009 Valencia, Spain.

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http://dx.doi.org/10.1007/BF02708748DOI Listing
April 2005

MYCN gain and MYCN amplification in a stage 4S neuroblastoma.

Cancer Genet Cytogenet 2003 Jan;140(2):157-61

Deparment of Pathology, Medical School, University of Valencia, Avda. Blasco Ibañez, 17,46010 Valencia, Spain.

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http://dx.doi.org/10.1016/s0165-4608(02)00677-5DOI Listing
January 2003