Publications by authors named "Rosa Luna"

32Publications

Remediation by means of EDTA of an agricultural calcareous soil polluted with Pb.

Environ Geochem Health 2020 Oct 22. Epub 2020 Oct 22.

Departamento de Energía, Unidad Azcapotzalco, Universidad Autónoma Metropolitana, Av. San Pablo 180, 02200, Ciudad de México, México.

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http://dx.doi.org/10.1007/s10653-020-00754-5DOI Listing
October 2020

The THO Complex as a Paradigm for the Prevention of Cotranscriptional R-Loops.

Cold Spring Harb Symp Quant Biol 2019 3;84:105-114. Epub 2020 Jun 3.

Centro Andaluz de Biología Molecular y Medicina Regenerativa CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, 41092 Seville, Spain.

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http://dx.doi.org/10.1101/sqb.2019.84.039594DOI Listing
June 2020

Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability.

Cell Rep 2019 08;28(6):1551-1563.e7

Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville 41092, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693559PMC
August 2019

Human THO-Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability.

EMBO J 2017 12 26;36(23):3532-3547. Epub 2017 Oct 26.

Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Consejo Superior de Investigaciones Científicas-Universidad Pablo de Olavide-Universidad de Sevilla, Seville, Spain

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http://dx.doi.org/10.15252/embj.201797208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709763PMC
December 2017

Excess of Yra1 RNA-Binding Factor Causes Transcription-Dependent Genome Instability, Replication Impairment and Telomere Shortening.

PLoS Genet 2016 Apr 1;12(4):e1005966. Epub 2016 Apr 1.

Centro Andaluz de Biología Molecular y Medicina Regenerativa CABIMER, Universidad de Sevilla, Seville, Spain.

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http://dx.doi.org/10.1371/journal.pgen.1005966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818039PMC
April 2016

A genome-wide function of THSC/TREX-2 at active genes prevents transcription-replication collisions.

Nucleic Acids Res 2014 Oct 7;42(19):12000-14. Epub 2014 Oct 7.

Centro Andaluz de Biología Molecular y Medicina Regenerativa CABIMER, Universidad de Sevilla-CSIC, 41092 Seville, Spain

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http://dx.doi.org/10.1093/nar/gku906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231764PMC
October 2014

R-loop mediated transcription-associated recombination in trf4Δ mutants reveals new links between RNA surveillance and genome integrity.

PLoS One 2013 7;8(6):e65541. Epub 2013 Jun 7.

Departamento de Biología Molecular, Centro Andaluz de Biología Molecular y Medicina Regenerativa CABIMER, Universidad de Sevilla, Seville, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065541PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676323PMC
January 2014

New clues to understand the role of THO and other functionally related factors in mRNP biogenesis.

Biochim Biophys Acta 2012 Jun 20;1819(6):514-20. Epub 2011 Dec 20.

Centro Andaluz de Biología Molecular y Medicina Regenerativa CABIMER, Universidad de Sevilla-CSIC, Av Américo Vespucio s/n, 41092 Sevilla, Spain. rlvarp@is/es

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https://linkinghub.elsevier.com/retrieve/pii/S18749399110022
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http://dx.doi.org/10.1016/j.bbagrm.2011.11.012DOI Listing
June 2012

Genome instability and transcription elongation impairment in human cells depleted of THO/TREX.

PLoS Genet 2011 Dec 1;7(12):e1002386. Epub 2011 Dec 1.

Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Universidad de Sevilla - Consejo Superior de Investigaciones Científicas (CSIC), Sevilla, Spain.

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https://dx.plos.org/10.1371/journal.pgen.1002386
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http://dx.doi.org/10.1371/journal.pgen.1002386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228816PMC
December 2011

Nab2 functions in the metabolism of RNA driven by polymerases II and III.

Mol Biol Cell 2011 Aug 16;22(15):2729-40. Epub 2011 Jun 16.

Centro Andaluz de Biología Molecular y Medicina Regenerativa, Universidad de Sevilla-Consejo Superior de Investigaciones Científicas, 41092 Seville, Spain.

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http://www.molbiolcell.org/doi/10.1091/mbc.e11-01-0055
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http://dx.doi.org/10.1091/mbc.E11-01-0055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145548PMC
August 2011

A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors.

EMBO J 2011 May 8;30(10):1953-64. Epub 2011 Apr 8.

Centro Andaluz de Biología Molecular y Medicina Regenerativa CABIMER, Universidad de Sevilla-CSIC, Sevilla, Spain.

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http://emboj.embopress.org/cgi/doi/10.1038/emboj.2011.109
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http://dx.doi.org/10.1038/emboj.2011.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098481PMC
May 2011

Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers.

BMC Cancer 2011 Feb 17;11:77. Epub 2011 Feb 17.

Centro Andaluz de Biología Molecular y Medicina Regenerativa CABIMER, Universidad de Sevilla-CSIC, Av, Américo Vespucio s/n, 41092 Sevilla, Spain.

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http://dx.doi.org/10.1186/1471-2407-11-77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050854PMC
February 2011

Female-biased incidence of experimental autoimmune encephalomyelitis reflects sexually dimorphic expression of surface CTLA-4 (CD152) on T lymphocytes.

Gend Med 2010 Aug;7(4):296-308

Department of Experimental Pediatrics, Otto-von-Guericke University, Magdeburg, Germany.

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http://dx.doi.org/10.1016/j.genm.2010.08.005DOI Listing
August 2010

The SWI/SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING finger protein Unkempt.

FEBS J 2010 Mar 8;277(6):1453-64. Epub 2010 Feb 8.

Institut Cochin, Université Paris Descartes, CNRS (UMR8104), Paris, France.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07575.xDOI Listing
March 2010

Transcription at the proximity of the nuclear pore: a role for the THP1-SAC3-SUS1-CDC31 (THSC) complex.

RNA Biol 2009 Apr-Jun;6(2):145-8. Epub 2009 Apr 8.

Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Universidad de Sevilla-CSIC, Seville, Spain.

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http://dx.doi.org/10.4161/rna.6.2.7803DOI Listing
February 2010

A reduction in RNA polymerase II initiation rate suppresses hyper-recombination and transcription-elongation impairment of THO mutants.

Mol Genet Genomics 2008 Oct 6;280(4):327-36. Epub 2008 Aug 6.

Centro Andaluz de Biologia Molecular y Medicina Regenerativa CABIMER, Universidad de Sevilla-CSIC, Av. Américo Vespucio s/n, 41092 Sevilla, Spain.

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http://dx.doi.org/10.1007/s00438-008-0368-8DOI Listing
October 2008

The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.

Mol Biol Cell 2008 Oct 30;19(10):4310-8. Epub 2008 Jul 30.

Centro Andaluz de Biologia Molecular y Medicina Regenerativa, Universidad de Sevilla-CSIC, 41092 Sevilla, Spain.

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http://www.molbiolcell.org/doi/10.1091/mbc.e08-04-0355
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http://dx.doi.org/10.1091/mbc.e08-04-0355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2555943PMC
October 2008

Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus.

Chromosoma 2008 Aug 22;117(4):319-31. Epub 2008 Apr 22.

Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Universidad de Sevilla-CSIC, Seville, Spain.

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http://link.springer.com/10.1007/s00412-008-0158-4
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http://dx.doi.org/10.1007/s00412-008-0158-4DOI Listing
August 2008

Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity.

Mol Genet Genomics 2008 Feb 25;279(2):123-32. Epub 2007 Oct 25.

Departamento de Biología Molecular, CABIMER, CSIC, Universidad de Sevilla, Av. Américo Vespucio s/n, Seville, Spain.

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http://dx.doi.org/10.1007/s00438-007-0301-6DOI Listing
February 2008

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

Authors:
Ewan Birney John A Stamatoyannopoulos Anindya Dutta Roderic Guigó Thomas R Gingeras Elliott H Margulies Zhiping Weng Michael Snyder Emmanouil T Dermitzakis Robert E Thurman Michael S Kuehn Christopher M Taylor Shane Neph Christoph M Koch Saurabh Asthana Ankit Malhotra Ivan Adzhubei Jason A Greenbaum Robert M Andrews Paul Flicek Patrick J Boyle Hua Cao Nigel P Carter Gayle K Clelland Sean Davis Nathan Day Pawandeep Dhami Shane C Dillon Michael O Dorschner Heike Fiegler Paul G Giresi Jeff Goldy Michael Hawrylycz Andrew Haydock Richard Humbert Keith D James Brett E Johnson Ericka M Johnson Tristan T Frum Elizabeth R Rosenzweig Neerja Karnani Kirsten Lee Gregory C Lefebvre Patrick A Navas Fidencio Neri Stephen C J Parker Peter J Sabo Richard Sandstrom Anthony Shafer David Vetrie Molly Weaver Sarah Wilcox Man Yu Francis S Collins Job Dekker Jason D Lieb Thomas D Tullius Gregory E Crawford Shamil Sunyaev William S Noble Ian Dunham France Denoeud Alexandre Reymond Philipp Kapranov Joel Rozowsky Deyou Zheng Robert Castelo Adam Frankish Jennifer Harrow Srinka Ghosh Albin Sandelin Ivo L Hofacker Robert Baertsch Damian Keefe Sujit Dike Jill Cheng Heather A Hirsch Edward A Sekinger Julien Lagarde Josep F Abril Atif Shahab Christoph Flamm Claudia Fried Jörg Hackermüller Jana Hertel Manja Lindemeyer Kristin Missal Andrea Tanzer Stefan Washietl Jan Korbel Olof Emanuelsson Jakob S Pedersen Nancy Holroyd Ruth Taylor David Swarbreck Nicholas Matthews Mark C Dickson Daryl J Thomas Matthew T Weirauch James Gilbert Jorg Drenkow Ian Bell XiaoDong Zhao K G Srinivasan Wing-Kin Sung Hong Sain Ooi Kuo Ping Chiu Sylvain Foissac Tyler Alioto Michael Brent Lior Pachter Michael L Tress Alfonso Valencia Siew Woh Choo Chiou Yu Choo Catherine Ucla Caroline Manzano Carine Wyss Evelyn Cheung Taane G Clark James B Brown Madhavan Ganesh Sandeep Patel Hari Tammana Jacqueline Chrast Charlotte N Henrichsen Chikatoshi Kai Jun Kawai Ugrappa Nagalakshmi Jiaqian Wu Zheng Lian Jin Lian Peter Newburger Xueqing Zhang Peter Bickel John S Mattick Piero Carninci Yoshihide Hayashizaki Sherman Weissman Tim Hubbard Richard M Myers Jane Rogers Peter F Stadler Todd M Lowe Chia-Lin Wei Yijun Ruan Kevin Struhl Mark Gerstein Stylianos E Antonarakis Yutao Fu Eric D Green Ulaş Karaöz Adam Siepel James Taylor Laura A Liefer Kris A Wetterstrand Peter J Good Elise A Feingold Mark S Guyer Gregory M Cooper George Asimenos Colin N Dewey Minmei Hou Sergey Nikolaev Juan I Montoya-Burgos Ari Löytynoja Simon Whelan Fabio Pardi Tim Massingham Haiyan Huang Nancy R Zhang Ian Holmes James C Mullikin Abel Ureta-Vidal Benedict Paten Michael Seringhaus Deanna Church Kate Rosenbloom W James Kent Eric A Stone Serafim Batzoglou Nick Goldman Ross C Hardison David Haussler Webb Miller Arend Sidow Nathan D Trinklein Zhengdong D Zhang Leah Barrera Rhona Stuart David C King Adam Ameur Stefan Enroth Mark C Bieda Jonghwan Kim Akshay A Bhinge Nan Jiang Jun Liu Fei Yao Vinsensius B Vega Charlie W H Lee Patrick Ng Atif Shahab Annie Yang Zarmik Moqtaderi Zhou Zhu Xiaoqin Xu Sharon Squazzo Matthew J Oberley David Inman Michael A Singer Todd A Richmond Kyle J Munn Alvaro Rada-Iglesias Ola Wallerman Jan Komorowski Joanna C Fowler Phillippe Couttet Alexander W Bruce Oliver M Dovey Peter D Ellis Cordelia F Langford David A Nix Ghia Euskirchen Stephen Hartman Alexander E Urban Peter Kraus Sara Van Calcar Nate Heintzman Tae Hoon Kim Kun Wang Chunxu Qu Gary Hon Rosa Luna Christopher K Glass M Geoff Rosenfeld Shelley Force Aldred Sara J Cooper Anason Halees Jane M Lin Hennady P Shulha Xiaoling Zhang Mousheng Xu Jaafar N S Haidar Yong Yu Yijun Ruan Vishwanath R Iyer Roland D Green Claes Wadelius Peggy J Farnham Bing Ren Rachel A Harte Angie S Hinrichs Heather Trumbower Hiram Clawson Jennifer Hillman-Jackson Ann S Zweig Kayla Smith Archana Thakkapallayil Galt Barber Robert M Kuhn Donna Karolchik Lluis Armengol Christine P Bird Paul I W de Bakker Andrew D Kern Nuria Lopez-Bigas Joel D Martin Barbara E Stranger Abigail Woodroffe Eugene Davydov Antigone Dimas Eduardo Eyras Ingileif B Hallgrímsdóttir Julian Huppert Michael C Zody Gonçalo R Abecasis Xavier Estivill Gerard G Bouffard Xiaobin Guan Nancy F Hansen Jacquelyn R Idol Valerie V B Maduro Baishali Maskeri Jennifer C McDowell Morgan Park Pamela J Thomas Alice C Young Robert W Blakesley Donna M Muzny Erica Sodergren David A Wheeler Kim C Worley Huaiyang Jiang George M Weinstock Richard A Gibbs Tina Graves Robert Fulton Elaine R Mardis Richard K Wilson Michele Clamp James Cuff Sante Gnerre David B Jaffe Jean L Chang Kerstin Lindblad-Toh Eric S Lander Maxim Koriabine Mikhail Nefedov Kazutoyo Osoegawa Yuko Yoshinaga Baoli Zhu Pieter J de Jong
June 2007

Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS.

Cell Cycle 2007 Jul 20;6(13):1594-604. Epub 2007 Apr 20.

Biomedical Sciences Graduate Program, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California 92093, USA.

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http://www.tandfonline.com/doi/abs/10.4161/cc.6.13.4336
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http://dx.doi.org/10.4161/cc.6.13.4336DOI Listing
July 2007

An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination.

Mol Cell Biol 2006 Oct 14;26(20):7451-65. Epub 2006 Aug 14.

Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Avd. Reina Mercedes 6, 41012 Sevilla, Spain.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.00684-06
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http://dx.doi.org/10.1128/MCB.00684-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636866PMC
October 2006

Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants.

Mol Cell Biol 2006 Jun;26(12):4387-98

Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Avd. Reina Mercedes 6, 41012 Sevilla, Spain.

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http://dx.doi.org/10.1128/MCB.00234-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489133PMC
June 2006

Direct isolation and identification of promoters in the human genome.

Genome Res 2005 Jun 17;15(6):830-9. Epub 2005 May 17.

Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1101/gr.3430605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142473PMC
June 2005

Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism.

J Biol Chem 2003 Jun 17;278(26):24225-32. Epub 2003 Apr 17.

Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Avenida Reina Mercedes 6, 41012 Sevilla, Spain.

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http://dx.doi.org/10.1074/jbc.M302900200DOI Listing
June 2003

Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis.

Nat Genet 2002 Oct 23;32(2):306-11. Epub 2002 Sep 23.

Instituto de Recursos Naturales y Agrobiología, Consejo Superior Investigaciones Científicas, Apdo 1052, 41080-Sevilla, Spain.

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http://www.nature.com/articles/ng997
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http://dx.doi.org/10.1038/ng997DOI Listing
October 2002

Characterization of two highly similar Rad51 homologs of Physcomitrella patens.

J Mol Biol 2002 Feb;316(1):35-49

Departamento de Biotecnología Microbiana, Centro Nacional de Biotecnología, CSIC, Cantoblanco, Campus Universidad Autónoma de Madrid, 28049, Spain.

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http://dx.doi.org/10.1006/jmbi.2001.5336DOI Listing
February 2002