Roopali Gandhi

Roopali Gandhi

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Roopali Gandhi

Roopali Gandhi

Publications by authors named "Roopali Gandhi"

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Biomarkers in Multiple Sclerosis.

Cold Spring Harb Perspect Med 2019 Mar 1;9(3). Epub 2019 Mar 1.

Department of Neurology, Ann Romney Center for Neurological Diseases, Brigham and Women's Hospital, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1101/cshperspect.a029058DOI Listing
March 2019

MRI phenotypes in MS: Longitudinal changes and miRNA signatures.

Neurol Neuroimmunol Neuroinflamm 2019 Mar 14;6(2):e530. Epub 2019 Feb 14.

Departments of Neurology (C.C.H., B.C.H., S.T., M.A.M., F.J.Q., R.G., H.L.W, R.B.) and Department of Radiology (R.B.); Brigham and Women's Hospital (C.C.H., B.C.H., S.T., M.A.M., F.J.Q., R.G., H.L.W, R.B.); Laboratory for Neuroimaging Research (C.C.H., S.T., R.H.); Partners Multiple Sclerosis Center (C.C.H., B.C.H., S.T., M.A.M., F.J.Q., R.G., H.L.W, R.B.); Ann Romney Center for Neurologic Diseases (C.C.H., B.C.H., S.T., M.A.M., F.J.Q., R.G., H.L.W, R.B.); and Harvard Medical School (C.C.H., B.C.H., S.T., M.A.M., F.J.Q., R.G., H.L.W., R.B.), Boston, MA.

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http://dx.doi.org/10.1212/NXI.0000000000000530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384020PMC
March 2019

Monomethyl fumarate treatment impairs maturation of human myeloid dendritic cells and their ability to activate T cells.

Mult Scler 2019 01 6;25(1):63-71. Epub 2017 Nov 6.

Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://journals.sagepub.com/doi/10.1177/1352458517740213
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http://dx.doi.org/10.1177/1352458517740213DOI Listing
January 2019

Isolation of Extracellular RNA from Serum/Plasma.

Methods Mol Biol 2018 ;1740:43-57

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center (MDACC), Houston, TX, USA.

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http://dx.doi.org/10.1007/978-1-4939-7652-2_5DOI Listing
January 2019

Identification of MS-specific serum miRNAs in an international multicenter study.

Neurol Neuroimmunol Neuroinflamm 2018 Sep 20;5(5):e491. Epub 2018 Aug 20.

Partners Multiple Sclerosis Center (K.R., B.C.H., A.P., M.A.M., R.R., P.K., T.C., H.L.W., R.G.), Brigham and Women's Hospital; Department of Neurology, Harvard Medical School (B.C.H., C.D.-C., B.I.G., T.C., H.L.W, R.G.), Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital; Biostatistics Center (B.C.H.); Massachusetts General Hospital, Boston, MA; Department of Clinical Neuroscience, Neuroimmunology Unit (M.J., F.P., T.O., M.K.), Karolinska Institute, Stockholm, Sweden; Department of Neurology (S.H., J.O.), School of Medicine, University of California, San Francisco; and Nehme and Therese Tohme Multiple Sclerosis Center (S.J.K.), Faculty of Medicine, American University of Beirut Medical Center, Lebanon.

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http://dx.doi.org/10.1212/NXI.0000000000000491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117192PMC
September 2018

Correlating serum micrornas and clinical parameters in amyotrophic lateral sclerosis.

Muscle Nerve 2018 Aug 25;58(2):261-269. Epub 2018 Mar 25.

Department of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/mus.26106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103911PMC
August 2018

A probiotic modulates the microbiome and immunity in multiple sclerosis.

Ann Neurol 2018 06 8;83(6):1147-1161. Epub 2018 Jun 8.

Ann Romney Center for Neurologic Diseases, Partners Multiple Sclerosis Center, Brigham and Women's Hospital, Department of Neurology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1002/ana.25244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181139PMC
June 2018

Investigation of probiotics in multiple sclerosis.

Mult Scler 2018 01;24(1):58-63

Ann Romney Center for Neurologic Diseases, Evergrande Center for Immunologic Diseases, Partners Multiple Sclerosis Center, Brigham and Women's Hospital and Department of Neurology, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1177/1352458517737390DOI Listing
January 2018

Association Between Serum MicroRNAs and Magnetic Resonance Imaging Measures of Multiple Sclerosis Severity.

JAMA Neurol 2017 03;74(3):275-285

Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts3Partners Multiple Sclerosis Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts4Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2016.5197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014611PMC
March 2017

FXR1: Linking cellular quiescence, immune genes and cancer.

Cell Cycle 2016 10 26;15(20):2695-6. Epub 2016 Jul 26.

a Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital , Boston , MA , USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053567PMC
http://dx.doi.org/10.1080/15384101.2016.1215692DOI Listing
October 2016

Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis.

Neurol Neuroimmunol Neuroinflamm 2016 Oct 23;3(5):e267. Epub 2016 Aug 23.

Ann Romney Center for Neurologic Diseases (K.R., A.P., B.H., F.v.G., M.A.M., R.R., P.K., T.C., H.L.W., R.G.), and Partners MS Center (C.D.-C., T.G., P.N., B.I.G., T.C., H.L.W.), Brigham & Women's Hospital, Harvard Medical School, Boston; and Biostatistics Center (B.H.), Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1212/NXI.0000000000000267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996540PMC
October 2016

AHR Activation Is Protective against Colitis Driven by T Cells in Humanized Mice.

Cell Rep 2016 10;17(5):1318-1329

Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA; The Broad Institute of MIT and Harvard University, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.09.082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106873PMC
October 2016

Dysregulation of regulatory CD56(bright) NK cells/T cells interactions in multiple sclerosis.

J Autoimmun 2016 08 4;72:8-18. Epub 2016 May 4.

Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Largo Daneo 3, 16132 Genova, Italy; Centre of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 9, 1612 Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2016.04.003DOI Listing
August 2016

Alterations of the human gut microbiome in multiple sclerosis.

Nat Commun 2016 06 28;7:12015. Epub 2016 Jun 28.

Ann Romney Center for Neurologic Diseases, Evergrande Center for Immunologic Diseases, Partners Multiple Sclerosis Center, Brigham and Women's Hospital, Department of Neurology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ncomms12015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931233PMC
June 2016

The Host Shapes the Gut Microbiota via Fecal MicroRNA.

Cell Host Microbe 2016 Jan;19(1):32-43

Department of Neurology, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847146PMC
January 2016

Effect of natalizumab treatment on circulating plasmacytoid dendritic cells: a cross-sectional observational study in patients with multiple sclerosis.

PLoS One 2014 30;9(7):e103716. Epub 2014 Jul 30.

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Partners Multiple Sclerosis Center, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Abu Haidar Neuroscience Institute, American University of Beirut, Beirut, Lebanon.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103716PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116240PMC
November 2015

miRNA in multiple sclerosis: search for novel biomarkers.

Authors:
Roopali Gandhi

Mult Scler 2015 Aug 28;21(9):1095-103. Epub 2015 Apr 28.

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http://dx.doi.org/10.1177/1352458515578771DOI Listing
August 2015

Circulating microRNAs as biomarkers for disease staging in multiple sclerosis.

Ann Neurol 2013 Jun 8;73(6):729-40. Epub 2013 Jul 8.

Partners Multiple Sclerosis Center, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.

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http://doi.wiley.com/10.1002/ana.23880
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http://dx.doi.org/10.1002/ana.23880DOI Listing
June 2013

Increased Th17 response to myelin peptides in pediatric MS.

Clin Immunol 2013 Mar 28;146(3):176-84. Epub 2012 Dec 28.

Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.clim.2012.12.008DOI Listing
March 2013

Accurate measurement of peripheral blood mononuclear cell concentration using image cytometry to eliminate RBC-induced counting error.

J Immunol Methods 2013 Feb 29;388(1-2):25-32. Epub 2012 Nov 29.

Department of Technology R&D, Nexcelom Bioscience LLC, Lawrence, MA 01843, USA.

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http://dx.doi.org/10.1016/j.jim.2012.11.010DOI Listing
February 2013

IL-27 imparts immunoregulatory function to human NK cell subsets.

PLoS One 2011 19;6(10):e26173. Epub 2011 Oct 19.

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026173PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198386PMC
February 2012

Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells.

Nat Immunol 2010 Sep 1;11(9):846-53. Epub 2010 Aug 1.

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/ni.1915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929008PMC
September 2010

Role of the innate immune system in the pathogenesis of multiple sclerosis.

J Neuroimmunol 2010 Apr;221(1-2):7-14

Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.jneuroim.2009.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854189PMC
April 2010

Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE.

Nat Immunol 2009 Sep 16;10(9):958-64. Epub 2009 Aug 16.

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ni.1775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746562PMC
September 2009

New immunosuppressive approaches: oral administration of CD3-specific antibody to treat autoimmunity.

J Neurol Sci 2008 Nov 18;274(1-2):9-12. Epub 2008 Sep 18.

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.jns.2008.07.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167084PMC
November 2008

In vitro induction of regulatory T cells by anti-CD3 antibody in humans.

J Autoimmun 2008 Feb-Mar;30(1-2):21-8

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.jaut.2007.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2239265PMC
April 2008

Membrane bound IL-15 is increased on CD14 monocytes in early stages of MS.

J Neuroimmunol 2008 Mar 1;195(1-2):135-9. Epub 2008 Apr 1.

Center for Neurological Diseases, Brigham and Women's Hospital, Harvard Medical, School, Boston Massachusetts 02115, United States.

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http://dx.doi.org/10.1016/j.jneuroim.2008.01.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747383PMC
March 2008

Cutting Edge: Immature human dendritic cells express latency-associated peptide and inhibit T cell activation in a TGF-beta-dependent manner.

J Immunol 2007 Apr;178(7):4017-21

Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.4049/jimmunol.178.7.4017DOI Listing
April 2007

Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25- LAP+ T cells.

Nat Med 2006 Jun 21;12(6):627-35. Epub 2006 May 21.

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

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http://www.nature.com/articles/nm1408
Publisher Site
http://dx.doi.org/10.1038/nm1408DOI Listing
June 2006