Publications by authors named "Ronan MacLoughlin"

35Publications

Targeting eosinophils in respiratory diseases: Biological axis, emerging therapeutics and treatment modalities.

Authors:
Li-Yen Lee Geena Suet Yin Hew Meenu Mehta Shakti D Shukla Saurabh Satija Navneet Khurana Krishnan Anand Harish Dureja Sachin Kumar Singh Vijay Mishra Pankaj Kumar Singh Monica Gulati Parteek Prasher Alaa A A Aljabali Murtaza M Tambuwala Lakshmi Thangavelu Jithendra Panneerselvam Gaurav Gupta Flavia C Zacconi Madhur Shastri Niraj Kumar Jha Dikaia Xenaki Ronan MacLoughlin Brian G Oliver Dinesh Kumar Chellappan Kamal Dua

Life Sci 2021 Jan 2;267:118973. Epub 2021 Jan 2.

Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, NSW 2007, Australia; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute (HMRI), University of Newcastle, New Lambton Heights, Newcastle, NSW 2305, Australia; School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh 173229, India. Electronic address:

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January 2021

Simultaneous Aerosol and Intramuscular Immunization with Influenza Vaccine Induces Powerful Protective Local T Cell and Systemic Antibody Immune Responses in Pigs.

Authors:
Veronica Martini Basu Paudyal Tiphany Chrun Adam McNee Matthew Edmans Emmanuel Atangana Maze Beckie Clark Alejandro Nunez Garry Dolton Andrew Sewell Peter Beverley Ronan MacLoughlin Alain Townsend Elma Tchilian

J Immunol 2020 Dec 16. Epub 2020 Dec 16.

The Pirbright Institute, Pirbright GU24 0NF, United Kingdom;

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December 2020

An In Vitro Investigation of the Release of Fugitive Medical Aerosols into the Environment during Manual Ventilation.

Authors:
Marc Mac Giolla Eain Mary Joyce Andrew O'Sullivan James A McGrath Ronan MacLoughlin

J Hosp Infect 2020 Dec 6. Epub 2020 Dec 6.

Aerogen, IDA Business Park, Dangan, Galway, Ireland; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons, Dublin, Ireland; School of Pharmacy and Pharmaceutical Sciences, Trinity College, Dublin, Ireland. Electronic address:

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December 2020

Aerosolized drug-loaded nanoparticles targeting migration inhibitory factors inhibit -induced inflammation and biofilm formation.

Authors:
Mohammad Doroudian Andrew O'Neill Ciaran O'Reilly Aisling Tynan Leona Mawhinney Aoife McElroy Shanice S Webster Ronan MacLoughlin Yuri Volkov Michelle E Armstrong George A O'Toole Adriele Prina-Mello Seamas C Donnelly

Nanomedicine (Lond) 2020 12 26;15(30):2933-2953. Epub 2020 Nov 26.

Department of Medicine, Tallaght University Hospital & Trinity College Dublin, Ireland.

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December 2020

Distribution of Droplets and Immune Responses After Aerosol and Intra-Nasal Delivery of Influenza Virus to the Respiratory Tract of Pigs.

Authors:
Veronica Martini Michael Hinchcliffe Elaine Blackshaw Mary Joyce Adam McNee Peter Beverley Alain Townsend Ronan MacLoughlin Elma Tchilian

Front Immunol 2020 27;11:594470. Epub 2020 Oct 27.

Department of Enhanced Host Responses, The Pirbright Institute, Pirbright, United Kingdom.

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October 2020

Defining a Regulatory Strategy for ATMP/Aerosol Delivery Device Combinations in the Treatment of Respiratory Disease.

Authors:
Niamh Woods Ronan MacLoughlin

Pharmaceutics 2020 Sep 26;12(10). Epub 2020 Sep 26.

School of Pharmacy & Biomolecular Sciences, Royal College of Surgeons in Ireland, D02 YN77 Dublin, Ireland.

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September 2020

State of the Art Review of Cell Therapy in the Treatment of Lung Disease, and the Potential for Aerosol Delivery.

Authors:
Hosanna Brave Ronan MacLoughlin

Int J Mol Sci 2020 Sep 3;21(17). Epub 2020 Sep 3.

Department of Chemistry, Royal College of Surgeons in Ireland, D02 YN77 Dublin, Ireland.

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September 2020

A narrative review on trans-nasal pulmonary aerosol delivery.

Authors:
Jie Li James B Fink Ronan MacLoughlin Rajiv Dhand

Crit Care 2020 08 17;24(1):506. Epub 2020 Aug 17.

Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.

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August 2020

Reducing Aerosol-Related Risk of Transmission in the Era of COVID-19: An Interim Guidance Endorsed by the International Society of Aerosols in Medicine.

Authors:
James B Fink Stephan Ehrmann Jie Li Patricia Dailey Paul McKiernan Chantal Darquenne Andrew R Martin Barbara Rothen-Rutishauser Philip J Kuehl Sabine Häussermann Ronan MacLoughlin Gerald C Smaldone Bernhard Muellinger Timothy E Corcoran Rajiv Dhand

J Aerosol Med Pulm Drug Deliv 2020 12 12;33(6):300-304. Epub 2020 Aug 12.

Department of Medicine, Graduate School of Medicine, University of Tennessee Health Science Center, Knoxville, Tennessee, USA.

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December 2020

In Vitro and In Vivo Assessment of PEGylated PEI for Anti-IL-8/CxCL-1 siRNA Delivery to the Lungs.

Authors:
Alan J Hibbitts Joanne M Ramsey James Barlow Ronan MacLoughlin Sally-Ann Cryan

Nanomaterials (Basel) 2020 Jun 27;10(7). Epub 2020 Jun 27.

School of Pharmacy & Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin D02 YN77, Ireland.

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June 2020

Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells.

Authors:
Chiara De Santi Elena Fernández Fernández Rachel Gaul Sebastian Vencken Arlene Glasgow Irene K Oglesby Killian Hurley Finn Hawkins Nilay Mitash Fangping Mu Rana Raoof David C Henshall Meritxell B Cutrona Jeremy C Simpson Brian J Harvey Barry Linnane Paul McNally Sally Ann Cryan Ronan MacLoughlin Agnieszka Swiatecka-Urban Catherine M Greene

Mol Ther 2020 04 6;28(4):1190-1199. Epub 2020 Feb 6.

Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin 9, Ireland.

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April 2020

In Vitro Study of the Effect of Breathing Pattern on Aerosol Delivery During High-Flow Nasal Therapy.

Authors:
Gavin Bennett Mary Joyce Louise Sweeney Ronan MacLoughlin

Pulm Ther 2019 Jun 6;5(1):43-54. Epub 2019 Feb 6.

Aerogen Limited, IDA Business Park, Dangan, Galway, Ireland.

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June 2019

Nebulized Mesenchymal Stem Cell Derived Conditioned Medium Retains Antibacterial Properties Against Clinical Pathogen Isolates.

Authors:
Sean D McCarthy Elizabeth Horgan Areeba Ali Claire Masterson John G Laffey Ronan MacLoughlin Daniel O'Toole

J Aerosol Med Pulm Drug Deliv 2020 06 15;33(3):140-152. Epub 2019 Nov 15.

Anaesthesia, School of Medicine, National University of Ireland Galway, Galway, Ireland.

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June 2020

Progress in mucosal immunization for protection against pneumococcal pneumonia.

Authors:
Viviane Maimoni Gonçalves Kan Kaneko Carla Solórzano Ronan MacLoughlin Imran Saleem Eliane Namie Miyaji

Expert Rev Vaccines 2019 08 23;18(8):781-792. Epub 2019 Jul 23.

e Laboratory of Bacteriology 2, Instituto Butantan , Sao Paulo , Brazil.

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August 2019

Nanotechnology based therapeutics for lung disease.

Authors:
Mohammad Doroudian Ronan MacLoughlin Fergus Poynton Adriele Prina-Mello Seamas C Donnelly

Thorax 2019 10 8;74(10):965-976. Epub 2019 Jul 8.

Department of Medicine, Tallaght University Hospital, Dublin 24 & Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland

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October 2019

Aerosolized recombinant human butyrylcholinesterase delivered by a nebulizer provides long term protection against inhaled paraoxon in macaques.

Authors:
Yvonne Rosenberg James Fink Ronan MacLoughlin Tara Ooms-Konecny Dennis Sullivan William Gerk Lingjun Mao Xiaoming Jiang Jonathan Lees Lori Urban Narayanan Rajendran

Chem Biol Interact 2019 Aug 12;309:108712. Epub 2019 Jun 12.

IIT Research Institute, Chicago, IL, 60616, USA.

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August 2019

Investigation of Fugitive Aerosols Released into the Environment during High-Flow Therapy.

Authors:
James A McGrath Ciarraí O'Toole Gavin Bennett Mary Joyce Miriam A Byrne Ronan MacLoughlin

Pharmaceutics 2019 Jun 1;11(6). Epub 2019 Jun 1.

Aerogen, IDA Business Park, Dangan, H91 HE94 Galway, Ireland.

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June 2019

Vibrating Mesh Nebulisation of Pro-Antimicrobial Peptides for Use in Cystic Fibrosis.

Authors:
Éanna Forde Graeme Kelly Louise Sweeney Deirdre Fitzgerald-Hughes Ronan MacLoughlin Marc Devocelle

Pharmaceutics 2019 May 17;11(5). Epub 2019 May 17.

Department of Chemistry, Royal College of Surgeons in Ireland (RCSI), 123 St. Stephen's Green, Dublin 2, Ireland.

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May 2019

The effect of UV-protected ethylene vinyl acetate (EVA) bags on the physicochemical stability of pediatric parenteral nutrition admixtures.

Authors:
Dorota Watrobska-Swietlikowska Ronan MacLoughlin

Daru 2019 Jun 17;27(1):255-264. Epub 2019 May 17.

Aerogen, IDA Business Park, Dangan, Galway, Ireland.

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June 2019

Nebulised lipid-polymer hybrid nanoparticles for the delivery of a therapeutic anti-inflammatory microRNA to bronchial epithelial cells.

Authors:
Sebastian Vencken Camilla Foged Joanne M Ramsey Louise Sweeney Sally-Ann Cryan Ronan J MacLoughlin Catherine M Greene

ERJ Open Res 2019 Apr 8;5(2). Epub 2019 Apr 8.

Lung Biology Group, Dept of Clinical Microbiology, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland.

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April 2019

Comparison of aerosol delivery across combinations of drug delivery interfaces with and without concurrent high-flow nasal therapy.

Authors:
Gavin Bennett Mary Joyce Elena Fernández Fernández Ronan MacLoughlin

Intensive Care Med Exp 2019 Apr 3;7(1):20. Epub 2019 Apr 3.

Aerogen Limited, IDA Business Park, Dangan, Galway, Ireland.

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April 2019

Effective nebulization of interferon-γ using a novel vibrating mesh.

Authors:
Louise Sweeney Alice P McCloskey Gerard Higgins Joanne M Ramsey Sally-Ann Cryan Ronan MacLoughlin

Respir Res 2019 Apr 3;20(1):66. Epub 2019 Apr 3.

Aerogen, IDA Business Park, Dangan, Galway, Ireland.

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April 2019

Investigation of the Quantity of Exhaled Aerosols Released into the Environment during Nebulisation.

Authors:
James A McGrath Andrew O'Sullivan Gavin Bennett Ciarraí O'Toole Mary Joyce Miriam A Byrne Ronan MacLoughlin

Pharmaceutics 2019 Feb 12;11(2). Epub 2019 Feb 12.

Aerogen, IDA Business Park, Dangan, Galway, H91 HE94, Ireland.

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February 2019

In Vitro Determination of the Main Effects in the Design of High-Flow Nasal Therapy Systems with Respect to Aerosol Performance.

Authors:
Gavin Bennett Mary Joyce Louise Sweeney Ronan MacLoughlin

Pulm Ther 2018 Jun 18;4(1):73-86. Epub 2018 Apr 18.

Aerogen Limited, IDA Business Park, Dangan, Galway, Ireland.

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June 2018

Comparison of Heterosubtypic Protection in Ferrets and Pigs Induced by a Single-Cycle Influenza Vaccine.

Authors:
Barbara Holzer Sophie B Morgan Yumi Matsuoka Matthew Edmans Francisco J Salguero Helen Everett Sharon M Brookes Emily Porter Ronan MacLoughlin Bryan Charleston Kanta Subbarao Alain Townsend Elma Tchilian

J Immunol 2018 06 27;200(12):4068-4077. Epub 2018 Apr 27.

The Pirbright Institute, Pirbright GU24 0NF, United Kingdom;

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June 2018

The presence of inorganic calcium in pediatric parenteral admixtures.

Authors:
Dorota Watrobska-Swietlikowska Agnieszka Szlagatys-Sidorkiewicz Ronan MacLoughlin

Nutr Hosp 2018 Jan 10;35(1):11-18. Epub 2018 Jan 10.

Department of Pharmaceutical Technology, Medical University of Gdansk, Poland.

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January 2018

Chemical Design of Both a Glutathione-Sensitive Dimeric Drug Guest and a Glucose-Derived Nanocarrier Host to Achieve Enhanced Osteosarcoma Lung Metastatic Anticancer Selectivity.

Authors:
Lu Su Richen Li Sarosh Khan Ryan Clanton Fuwu Zhang Yen-Nan Lin Yue Song Hai Wang Jingwei Fan Soleil Hernandez Andrew S Butters Gamal Akabani Ronan MacLoughlin Justin Smolen Karen L Wooley

J Am Chem Soc 2018 01 19;140(4):1438-1446. Epub 2018 Jan 19.

Departments of Chemistry, Chemical Engineering, and Materials Science & Engineering, Texas A&M University , College Station, Texas 77842, United States.

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January 2018

Biopolymer-Based Nanoparticles for Cystic Fibrosis Lung Gene Therapy Studies.

Authors:
Elena Fernández Fernández Beatriz Santos-Carballal Chiara de Santi Joanne M Ramsey Ronan MacLoughlin Sally-Ann Cryan Catherine M Greene

Materials (Basel) 2018 Jan 13;11(1). Epub 2018 Jan 13.

Lung Biology Group, Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland.

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January 2018

Aerosol: A Novel Vehicle for Pharmacotherapy in Neonates.

Authors:
Ronan MacLoughlin Colin Telfer Andy Clark James Fink

Curr Pharm Des 2017 ;23(38):5928-5934

Aerogen Pharma Corporation, 1660 S. Amphlett Blvd. Suite 360, San Mateo, CA 94402, United States.

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June 2019

Modified Vaccinia Virus Ankara Preferentially Targets Antigen Presenting Cells In Vitro, Ex Vivo and In Vivo.

Authors:
Arwen F Altenburg Carolien E van de Sandt Bobby W S Li Ronan J MacLoughlin Ron A M Fouchier Geert van Amerongen Asisa Volz Rudi W Hendriks Rik L de Swart Gerd Sutter Guus F Rimmelzwaan Rory D de Vries

Sci Rep 2017 08 17;7(1):8580. Epub 2017 Aug 17.

Department of Viroscience, Postgraduate School of Molecular Medicine, Erasmus MC, Rotterdam, The Netherlands.

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August 2017

Optimization and Dose Estimation of Aerosol Delivery to Non-Human Primates.

Authors:
Ronan J MacLoughlin Geert van Amerongen James B Fink Hettie M Janssens W Paul Duprex Rik L de Swart

J Aerosol Med Pulm Drug Deliv 2016 06 8;29(3):281-7. Epub 2015 Dec 8.

2 Department of Viroscience, Erasmus MC , Rotterdam, Netherlands .

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June 2016

Aerosol-mediated delivery of AAV2/6-IκBα attenuates lipopolysaccharide-induced acute lung injury in rats.

Authors:
Ronan J MacLoughlin Brendan D Higgins James Devaney Daniel O'Toole John G Laffey Timothy O'Brien

Hum Gene Ther 2015 Jan;26(1):36-46

1 Regenerative Medicine Institute (REMEDI), National University of Ireland , Galway, Ireland .

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January 2015

Magnetic core-shell nanoparticles for drug delivery by nebulization.

Authors:
Navin Kumar Verma Kieran Crosbie-Staunton Amro Satti Shane Gallagher Katie B Ryan Timothy Doody Colm McAtamney Ronan MacLoughlin Paul Galvin Conor S Burke Yuri Volkov Yurii K Gun'ko

J Nanobiotechnology 2013 Jan 23;11. Epub 2013 Jan 23.

Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland.

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January 2013

Nanoparticle-based drug delivery: case studies for cancer and cardiovascular applications.

Authors:
Paul Galvin Damien Thompson Katie B Ryan Anna McCarthy Anne C Moore Conor S Burke Maya Dyson Brian D Maccraith Yurii K Gun'ko Michelle T Byrne Yuri Volkov Chris Keely Enda Keehan Michael Howe Conor Duffy Ronan MacLoughlin

Cell Mol Life Sci 2012 Feb 21;69(3):389-404. Epub 2011 Oct 21.

Tyndall National Institute, University College Cork, Cork, Ireland.

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February 2012

Optimized aerosol delivery to a mechanically ventilated rodent.

Authors:
Ronan J MacLoughlin Brendan D Higgins John G Laffey Timothy O'Brien

J Aerosol Med Pulm Drug Deliv 2009 Dec;22(4):323-32

Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway, Ireland.

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December 2009