Ronald de Groot

Ronald de Groot

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Ronald de Groot

Publications by authors named "Ronald de Groot"

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Cerebrospinal fluid immunoglobulins are increased in neonates exposed to Zika virus during foetal life.

J Infect 2020 Jan 23. Epub 2020 Jan 23.

Federal University of Bahia School of Medicine, Paediatrics, Rua Prof. Aristides Novis, No. 105, Salvador, Bahia 40210-630, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2020.01.006DOI Listing
January 2020

Biosynthetic homeostasis and resilience of the complement system in health and infectious disease.

EBioMedicine 2019 Jul 29;45:303-313. Epub 2019 Jun 29.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands; Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ebiom.2019.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642076PMC
July 2019

Common Genetic Variants in the Complement System and their Potential Link with Disease Susceptibility and Outcome of Invasive Bacterial Infection.

J Innate Immun 2020 3;12(2):131-141. Epub 2019 Jul 3.

Section Paediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Nijmegen, The Netherlands,

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http://dx.doi.org/10.1159/000500545DOI Listing
July 2019

Big Data Analyses for Continuous Evaluation of Pharmacotherapy: A Proof of Principle with Doxapram in Preterm Infants.

Curr Pharm Des 2017 ;23(38):5919-5927

Department of Pediatrics, Division of Neonatology, Erasmus University Medical Center - Sophia Children's Hospital, Rotterdam, Netherlands.

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http://dx.doi.org/10.2174/1381612823666170918121556DOI Listing
June 2019

Nationwide Study on the Course of Influenza A (H1N1) Infections in Hospitalized Children in the Netherlands During the Pandemic 2009-2010.

Pediatr Infect Dis J 2018 12;37(12):e283-e291

From the Department of Pediatrics, Laboratory of Pediatric Infectious Diseases, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/INF.0000000000002177DOI Listing
December 2018

Large differences in neonatal drug use between NICUs are common practice: time for consensus?

Br J Clin Pharmacol 2018 06 17;84(6):1313-1323. Epub 2018 Apr 17.

Department of Pediatrics, Division of Neonatology, Erasmus University Medical Center - Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/bcp.13563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980600PMC
June 2018

Siglec-1 inhibits RSV-induced interferon gamma production by adult T cells in contrast to newborn T cells.

Eur J Immunol 2018 04 18;48(4):621-631. Epub 2018 Jan 18.

Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands.

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http://doi.wiley.com/10.1002/eji.201747161
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http://dx.doi.org/10.1002/eji.201747161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947594PMC
April 2018

Streptococcus pneumoniae PspC Subgroup Prevalence in Invasive Disease and Differences in Contribution to Complement Evasion.

Infect Immun 2018 04 22;86(4). Epub 2018 Mar 22.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands

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http://dx.doi.org/10.1128/IAI.00010-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865030PMC
April 2018

New legal requirements for submission of product information to poisons centres in EU member states.

Clin Toxicol (Phila) 2018 Jan 23;56(1):1-6. Epub 2017 Jun 23.

a National Poisons Information Center, University Medical Center Utrecht , Utrecht , The Netherlands.

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http://dx.doi.org/10.1080/15563650.2017.1339888DOI Listing
January 2018

Haemophilus is overrepresented in the nasopharynx of infants hospitalized with RSV infection and associated with increased viral load and enhanced mucosal CXCL8 responses.

Microbiome 2018 01 11;6(1):10. Epub 2018 Jan 11.

Laboratory of Pediatric Infectious Diseases, Radboud Center for Infectious Diseases, Radboud University Medical Center, Geert Grooteplein-Zuid 10 (Route 412), 6525, GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s40168-017-0395-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765694PMC
January 2018

Model-based clinical dose optimization for phenobarbital in neonates: An illustration of the importance of data sharing and external validation.

Eur J Pharm Sci 2017 Nov 12;109S:S90-S97. Epub 2017 May 12.

Division of Pharmacology, Leiden Academic Center for Drug Research, Gorlaeus Laboratories, Einsteinweg 55, 2333 CC Leiden, The Netherlands; Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands.

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http://dx.doi.org/10.1016/j.ejps.2017.05.026DOI Listing
November 2017

Sustained Viral Suppression in HIV-infected Children on Once-daily Lopinavir/Ritonavir in Clinical Practice.

Pediatr Infect Dis J 2017 Oct;36(10):976-980

From the *Department of Pediatrics, Division of Infectious Diseases and Immunology, Erasmus MC University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands; †Department of Pharmacy, and ‡Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands; and §Department of Pediatrics, Franciscus Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/INF.0000000000001627DOI Listing
October 2017

Characteristics of RSV-Specific Maternal Antibodies in Plasma of Hospitalized, Acute RSV Patients under Three Months of Age.

PLoS One 2017 30;12(1):e0170877. Epub 2017 Jan 30.

Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170877PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279754PMC
August 2017

Human newborn B cells mount an interferon-α/β receptor-dependent humoral response to respiratory syncytial virus.

J Allergy Clin Immunol 2017 06 5;139(6):1997-2000.e4. Epub 2016 Dec 5.

Boston Children's Hospital, Precision Vaccines Program, Division of Infectious Diseases, Department of Medicine, Boston, Mass; Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2016.10.032DOI Listing
June 2017

Prospective observational study in two Dutch hospitals to assess the performance of inflammatory plasma markers to determine disease severity of viral respiratory tract infections in children.

BMJ Open 2017 06 30;7(6):e014596. Epub 2017 Jun 30.

Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Center for Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1136/bmjopen-2016-014596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734420PMC
June 2017

Pitfalls in interpretation of CT-values of RT-PCR in children with acute respiratory tract infections.

J Clin Virol 2017 05 24;90:1-6. Epub 2017 Feb 24.

Franciscus Gasthuis en Vlietland, Department of Pediatrics, Postbus 10900, 3004BA Rotterdam, The Netherlands; Erasmus MC, University Medical Center Rotterdam, Department of Pediatric Infectious Diseases and Immunology, PO Box 2040, 3000CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jcv.2017.02.010DOI Listing
May 2017

A versatile assay to determine bacterial and host factors contributing to opsonophagocytotic killing in hirudin-anticoagulated whole blood.

Sci Rep 2017 02 8;7:42137. Epub 2017 Feb 8.

Laboratory of Pediatric Infectious Diseases, Radboud Center for Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/srep42137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296863PMC
February 2017

Single- and multiple viral respiratory infections in children: disease and management cannot be related to a specific pathogen.

BMC Infect Dis 2017 01 11;17(1):62. Epub 2017 Jan 11.

Department of Pediatrics, Franciscus Gasthuis en Vlietland, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/s12879-016-2118-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225597PMC
January 2017

Alternative pathway regulation by factor H modulates Streptococcus pneumoniae induced proinflammatory cytokine responses by decreasing C5a receptor crosstalk.

Cytokine 2016 12 6;88:281-286. Epub 2016 Oct 6.

Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboudumc, 6525 GA Nijmegen, The Netherlands; Pediatric Infectious Diseases and Immunology, Department of Pediatrics, Radboudumc, 6525 GA Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2016.09.025DOI Listing
December 2016

Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease.

J Infect Dis 2016 06 21;213(11):1820-7. Epub 2016 Jan 21.

Laboratory of Pediatric Infectious Diseases Division of Pediatric Infectious Diseases and Immunology, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/infdis/jiw029DOI Listing
June 2016

Reduced Expression of HLA-DR on Monocytes During Severe Respiratory Syncytial Virus Infections.

Pediatr Infect Dis J 2016 Mar;35(3):e89-96

From the Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/INF.0000000000001007DOI Listing
March 2016

High pneumococcal density correlates with more mucosal inflammation and reduced respiratory syncytial virus disease severity in infants.

BMC Infect Dis 2016 Mar 17;16:129. Epub 2016 Mar 17.

Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, P. O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12879-016-1454-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794819PMC
March 2016

Actin- and clathrin-dependent mechanisms regulate interferon gamma release after stimulation of human immune cells with respiratory syncytial virus.

Virol J 2016 Mar 22;13:52. Epub 2016 Mar 22.

Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Science, Radboud university medical center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12985-016-0506-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802911PMC
March 2016

Antibodies enhance CXCL10 production during RSV infection of infant and adult immune cells.

Cytokine 2015 Dec 5;76(2):458-464. Epub 2015 Aug 5.

Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10434666153003
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http://dx.doi.org/10.1016/j.cyto.2015.07.024DOI Listing
December 2015

What is the responsibility of national government with respect to vaccination?

Authors:
Ronald de Groot

Vaccine 2015 Nov 3;33(48):6511-2. Epub 2015 Jul 3.

Radboud University Medical Center, Department of Pediatrics, Laboratory of Pediatric Infectious Diseases and Oncology, Geert Grooteplein 10, 6525 GA Nijmegen, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.06.089DOI Listing
November 2015

Recurrent, protracted and persistent lower respiratory tract infection: A neglected clinical entity.

J Infect 2015 Jun 25;71 Suppl 1:S106-11. Epub 2015 Apr 25.

Department of Pediatrics, Radboud University Medical Centre, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2015.04.011DOI Listing
June 2015

Nasopharyngeal gene expression, a novel approach to study the course of respiratory syncytial virus infection.

Eur Respir J 2015 Mar 26;45(3):718-25. Epub 2014 Sep 26.

Laboratory of Pediatric Infectious Diseases, Dept of Pediatrics, Radboud University Medical Center, Nijmegen, The Netherlands Laboratory of Medical Immunology, Dept of Laboratory Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1183/09031936.00085614DOI Listing
March 2015

Dengue in children.

J Infect 2014 Nov 13;69 Suppl 1:S77-86. Epub 2014 Sep 13.

Department of Pediatrics, Radboud University Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2014.07.020DOI Listing
November 2014

Commentary: Continuous infusion of vancomycin in neonates: to use or not to use remains the question.

Pediatr Infect Dis J 2014 Jun;33(6):606-7

From the *Departments of Pediatrics, Divisions of Neonatology and Pediatric Pharmacology, and Pharmacology/Toxicology, University of Utah, Salt Lake City, UT; †Neonatal Intensive Care Unit, University Hospitals Leuven; ‡Department of Development and Regeneration, Catholic University Leuven, Leuven, Belgium; §Department of Pediatrics, University Medical Center Nijmegen, the Netherlands; ¶Division of Pediatric Clinical Pharmacology, Children's National Medical Center; ‖Departments of Pediatrics, Pharmacology, Physiology and Integrative Systems Biology, George Washington University School of Medicine and Health Sciences, Washington, DC; and **Intensive Care, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1097/INF.0000000000000244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709250PMC
June 2014

Influenza vaccination in kids, are you kidding me?

J Infect 2014 Jan 25;68 Suppl 1:S100-7. Epub 2013 Oct 25.

Department of Pediatrics, Laboratory of Pediatric Infectious Diseases, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2013.09.019DOI Listing
January 2014

Decreased expression of serum and microvascular vascular endothelial growth factor receptor-2 in meningococcal sepsis*.

Pediatr Crit Care Med 2013 Sep;14(7):682-5

1Department of Pediatrics, Radboud University Medical Centre, Nijmegen, The Netherlands. 2The Nijmegen Institute for Infection, Inflammation, and Immunity, Radboud University Medical Centre, Nijmegen, The Netherlands. 3Department of Immunology, Erasmus Medical Centre, Rotterdam, The Netherlands. 4Department of Dermatology, Erasmus Medical Centre, Rotterdam, The Netherlands. 5Pediatric Intensive Care Unit, University Medical Centre Utrecht, Utrecht, The Netherlands. 6Department of Pediatric Infectious Diseases and Immunology, Erasmus Medical Centre, Rotterdam, The Netherlands. 7Pediatric Intensive Care Unit, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/PCC.0b013e3182917ccbDOI Listing
September 2013

Elucidation and clinical role of emerging viral respiratory tract infections in children.

Adv Exp Med Biol 2013 ;764:191-204

Department of Pediatrics, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/978-1-4614-4726-9_16DOI Listing
June 2013

Bacterial respiratory pathogens in children with inherited immune and airway disorders: nasopharyngeal carriage and disease risk.

Pediatr Infect Dis J 2013 Apr;32(4):399-404

Department of Pediatrics, Laboratory of Pediatric Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/INF.0b013e31827db77aDOI Listing
April 2013

CD4+ T-cell counts and interleukin-8 and CCL-5 plasma concentrations discriminate disease severity in children with RSV infection.

Pediatr Res 2013 Feb 19;73(2):187-93. Epub 2012 Nov 19.

Department of Pediatrics, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/pr.2012.163DOI Listing
February 2013

Paediatric conferences: only a profit making enterprise?

Acta Paediatr 2012 Dec 10;101(12):1194-5. Epub 2012 Sep 10.

Dr von Hauner Children's Hospital, University of Munich Medical Centre, München, Germany.

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http://dx.doi.org/10.1111/apa.12003DOI Listing
December 2012

Use of MMP-8 and MMP-9 to assess disease severity in children with viral lower respiratory tract infections.

J Med Virol 2012 Sep;84(9):1471-80

Department of Pediatrics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/jmv.23301DOI Listing
September 2012

Infection with multiple viruses is not associated with increased disease severity in children with bronchiolitis.

Pediatr Pulmonol 2012 Apr 7;47(4):393-400. Epub 2011 Sep 7.

Department of Pediatrics, Radboud University Nijmegen Medical Centre, P.O. box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://doi.wiley.com/10.1002/ppul.21552
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http://dx.doi.org/10.1002/ppul.21552DOI Listing
April 2012

29th ESPID Annual Meeting in The Hague, the Netherlands.

Pediatr Infect Dis J 2012 Apr;31(4):404

Department of Pediatrics, Division of Pediatric Infectious Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/INF.0b013e31824ae9bfDOI Listing
April 2012

Implications of the new EU legislation on chemicals for Poisons Centres.

Clin Toxicol (Phila) 2011 Nov;49(9):794-8

National Poisons Information Center, University Medical Center Utrecht, The Netherlands.

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http://dx.doi.org/10.3109/15563650.2011.623129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231849PMC
November 2011

Chlamydia trachomatis and placental inflammation in early preterm delivery.

Eur J Epidemiol 2011 May 24;26(5):421-8. Epub 2011 Mar 24.

Department of Paediatric Infectious Disease and Immunology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10654-011-9569-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109244PMC
May 2011

Biomedical application of MALDI mass spectrometry for small-molecule analysis.

Mass Spectrom Rev 2011 Jan-Feb;30(1):101-20

Laboratories of Neuro-Oncology/Clinical and Cancer Proteomics, Department of Neurology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/mas.20268DOI Listing
April 2011

Coagulase-negative staphylococcal skin carriage among neonatal intensive care unit personnel: from population to infection.

J Clin Microbiol 2010 Nov 8;48(11):3876-81. Epub 2010 Sep 8.

Department of Pediatrics, Erasmus MC-Sophia Children’s Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1128/JCM.00967-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020886PMC
November 2010

Human immunodeficiency virus and tuberculosis coinfection in children: challenges in diagnosis and treatment.

Pediatr Infect Dis J 2010 Oct;29(10):e63-70

Division of Pediatric Infectious Diseases, Department of Pediatrics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/INF.0b013e3181ee23aeDOI Listing
October 2010

Polymorphisms in PARP, IL1B, IL4, IL10, C1INH, DEFB1, and DEFA4 in meningococcal disease in three populations.

Shock 2010 Jul;34(1):17-22

Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, University Medical Center, Dr Molewaterplein 60, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/SHK.0b013e3181ce2c7dDOI Listing
July 2010

Passive immunisation against respiratory syncytial virus: a cost-effectiveness analysis.

Arch Dis Child 2010 Jul 26;95(7):493-8. Epub 2010 May 26.

Department of Pediatrics, Erasmus MC-Sophia, Rotterdam 3000 CB, the Netherlands.

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http://dx.doi.org/10.1136/adc.2008.155556DOI Listing
July 2010

Reduced ADAMTS13 in children with severe meningococcal sepsis is associated with severity and outcome.

Thromb Haemost 2010 Jun 13;103(6):1181-7. Epub 2010 Apr 13.

Erasmus Medical Centre, Department of Hematology, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1160/TH09-06-0376DOI Listing
June 2010

The changes in hazard classification and product notification procedures of the new European CLP and Cosmetics Regulations.

Clin Toxicol (Phila) 2010 Jan;48(1):28-33

National Institute for Public Health and the Environment, National Poisons Information Centre, Bilthoven, The Netherlands.

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http://dx.doi.org/10.3109/15563650903376097DOI Listing
January 2010

Meropenem pharmacokinetics in the newborn.

Antimicrob Agents Chemother 2009 Sep 6;53(9):3871-9. Epub 2009 Jul 6.

Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

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http://dx.doi.org/10.1128/AAC.00351-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737888PMC
September 2009

Strain-specific impact of PsaR of Streptococcus pneumoniae on global gene expression and virulence.

Microbiology 2009 May 16;155(Pt 5):1569-1579. Epub 2009 Apr 16.

Laboratory of Pediatric Infectious Diseases, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands.

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http://mic.microbiologyresearch.org/content/journal/micro/10
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http://dx.doi.org/10.1099/mic.0.025072-0DOI Listing
May 2009

Factors associated with pneumococcal carriage in healthy Dutch infants: the generation R study.

J Pediatr 2008 Dec 14;153(6):771-6. Epub 2008 Jul 14.

Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands; department of Pediatrics, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jpeds.2008.05.061DOI Listing
December 2008

Quantitative analysis of antiretroviral drugs in lysates of peripheral blood mononuclear cells using MALDI-triple quadrupole mass spectrometry.

Anal Chem 2008 Jul 6;80(13):4969-75. Epub 2008 Jun 6.

Department of Neurology, Laboratory of Neuro-Oncology and Clinical & Cancer Proteomics, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/ac800218aDOI Listing
July 2008

Improved survival of children with sepsis and purpura: effects of age, gender, and era.

Crit Care 2007 ;11(5):R112

Department of Paediatrics, Division of Infectious Diseases and Immunology, Erasmus MC-Sophia Children's Hospital, University Medical Center, Dr, Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/cc6161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556765PMC
May 2008

Quantitative analysis of HIV-1 protease inhibitors in cell lysates using MALDI-FTICR mass spectrometry.

Anal Chem 2008 May 8;80(10):3751-6. Epub 2008 Apr 8.

Department of Neurology, Laboratory of Neuro-Oncology and Clinical and Cancer Proteomics, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/ac702072cDOI Listing
May 2008

Chlamydia trachomatis as a cause of neonatal conjunctivitis in Dutch infants.

Pediatrics 2008 Feb;121(2):e321-6

Department of Pediatrics, Erasmus Medical Centre, Sophia Children's Hospital, Dr Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands.

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http://dx.doi.org/10.1542/peds.2007-0153DOI Listing
February 2008

CodY of Streptococcus pneumoniae: link between nutritional gene regulation and colonization.

J Bacteriol 2008 Jan 16;190(2):590-601. Epub 2007 Nov 16.

Laboratory of Pediatric Infectious Diseases, Radboud University Nijmegen Medical Centre, P.O. Box 9101 (Route 224), 6500 HB Nijmegen, The Netherlands.

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http://jb.asm.org/cgi/doi/10.1128/JB.00917-07
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http://dx.doi.org/10.1128/JB.00917-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223708PMC
January 2008

Human metapneumovirus: an important cause of acute respiratory illness.

Adv Exp Med Biol 2006 ;582:251-64

Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/0-387-33026-7_21DOI Listing
October 2007

Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media.

Pediatrics 2007 Oct;120(4):814-23

Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, University Medical Center, Dr Molewaterplein 50, Room Ee15-02, 3015 GE, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1542/peds.2007-0524DOI Listing
October 2007

Two patients with complete defects in interferon gamma receptor-dependent signaling.

J Clin Immunol 2007 Sep 21;27(5):490-6. Epub 2007 May 21.

Department of Immunology, Erasmus MC/University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10875-007-9097-8DOI Listing
September 2007

Economic evaluation of targeted treatments of invasive aspergillosis in adult haematopoietic stem cell transplant recipients in the Netherlands: a modelling approach.

J Antimicrob Chemother 2007 Aug 7;60(2):385-93. Epub 2007 Jun 7.

Department of Health Organization Policy and Economics (HOPE), Faculty of Health Sciences, Maastricht University, Maastricht, and Department of General Internal Medicine, Bronovo Hospital, The Hague, The Netherlands.

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http://academic.oup.com/jac/article/60/2/385/713824/Economic
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http://dx.doi.org/10.1093/jac/dkm196DOI Listing
August 2007

The 4G/4G plasminogen activator inhibitor-1 genotype is associated with frequent recurrence of acute otitis media.

Pediatrics 2007 Aug;120(2):e317-23

Department of Pediatrics, Erasmus MC-Sophia Rotterdam, Dr Molewaterplein 50, Room Ee15-02, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1542/peds.2006-1390DOI Listing
August 2007

Validation of an HIV-1 inactivation protocol that is compatible with intracellular drug analysis by mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2007 Feb 20;847(1):38-44. Epub 2006 Oct 20.

Department of Neurology, Laboratory of Neuro-Oncology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jchromb.2006.10.001DOI Listing
February 2007

Pharmacokinetics of a once-daily regimen of lopinavir/ritonavir in HIV-1-infected children.

Antivir Ther 2006 ;11(4):439-45

Department of Clinical Pharmacy, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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August 2006

Qualitative and quantitative analysis of pharmaceutical compounds by MALDI-TOF mass spectrometry.

Anal Chem 2006 Aug;78(15):5403-11

Department of Neurology, Laboratory of Neuro-Oncology, and Department of Pediatrics, Division of Pediatric Infectious Diseases & Immunology, Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/ac060436iDOI Listing
August 2006

Detection of lipoatrophy in human immunodeficiency virus-1-infected children treated with highly active antiretroviral therapy.

Pediatr Infect Dis J 2006 May;25(5):427-31

Department of Paediatrics, Division of Paediatric Infectious Diseases and Immunology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/01.inf.0000215003.32256.aaDOI Listing
May 2006

Hospitalization for respiratory syncytial virus infection in young children: development of a clinical prediction rule.

Pediatr Infect Dis J 2006 Mar;25(3):201-7

Division of General Pediatrics, Department of Pediatrics, Erasmus Medical Centre-Sophia, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/01.inf.0000202135.24485.f8DOI Listing
March 2006

Pharmacokinetics of antiretroviral therapy in HIV-1-infected children.

Clin Pharmacokinet 2005 ;44(9):935-56

Department of Pediatrics, Erasmus MC/Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.2165/00003088-200544090-00004DOI Listing
December 2005

Porin A-specific antibody avidity in patients who are convalescing from meningococcal B disease.

Pediatr Res 2005 Jul 17;58(1):149-52. Epub 2005 Mar 17.

Laboratory for Vaccine Research, Netherlands Vaccine Institute, 3720 AL Bilthoven, The Netherlands.

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http://dx.doi.org/10.1203/01.PDR.0000156372.13569.08DOI Listing
July 2005

Increased dose of lopinavir/ritonavir compensates for efavirenz-induced drug-drug interaction in HIV-1-infected children.

J Acquir Immune Defic Syndr 2005 May;39(1):63-8

Department of Clinical Pharmacy, University Medical Center, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/01.qai.0000155203.89350.85DOI Listing
May 2005

Reactogenicity of acellular pertussis vaccine in 4-year-olds in The Netherlands.

Vaccine 2004 Sep;22(25-26):3256-7

Erasmus MC-Sophia Children's Hospital, Room SP 2456, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.vaccine.2004.03.010DOI Listing
September 2004

Maintaining the nelfinavir trough concentration above 0.8 mg/L improves virologic response in HIV-1-infected children.

J Pediatr 2004 Sep;145(3):403-5

University Medical Centre Nijmegen, Nijmegen University Centre for Infectious Diseases, Geert Grooteplein 8, 6525 GA Nijmegen, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S002234760400365
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http://dx.doi.org/10.1016/j.jpeds.2004.04.048DOI Listing
September 2004