Publications by authors named "Ronald M Laxer"

100Publications

A 10-year-old girl with cervical lymphadenopathy, fever, and cytopenia.

Paediatr Child Health 2020 Oct 29;25(6):342-344. Epub 2019 Aug 29.

Department of Paediatrics, The Hospital for Sick Children, The University of Toronto, Toronto, Ontario.

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http://dx.doi.org/10.1093/pch/pxz114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492631PMC
October 2020

Whole-body MRI Quantification for Assessment of Bone Lesions in CNO Patients Treated with Pamidronate: A Prevalence, Reproducibility, and Responsiveness Study.

J Rheumatol 2020 Sep 15. Epub 2020 Sep 15.

From the Department of Radiodiagnosis, Christian Medical College and Hospital, Vellore, India; Department of Diagnostic Imaging, The Hospital for Sick Children, Department of Medical Imaging, University of Toronto, Toronto, ON, Canada; Division of Pediatric Rheumatology, Department of Pediatrics, University of Alberta; Edmonton, AB, Canada; Division of Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada. Address correspondence to Jyoti Panwar, MD, FRCR, Professor, Department of Radiodiagnosis, Christian Medical College and Hospital, Vellore, India, Phone: +91-638-5209-311. Department of Diagnostic Imaging, The Hospital for Sick Children, Department of Medical Imaging, University of Toronto, Toronto, ON, Canada. Email:

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http://dx.doi.org/10.3899/jrheum.200329DOI Listing
September 2020

Follow the complex bread crumbs: A review of autoinflammation for the general paediatrician.

Paediatr Child Health 2020 Aug 18;25(5):279-285. Epub 2019 Jul 18.

Pediatric Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, Ontario.

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http://dx.doi.org/10.1093/pch/pxz072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395328PMC
August 2020

Monogenic autoinflammatory diseases in children: single center experience with clinical, genetic, and imaging review.

Insights Imaging 2020 Jul 31;11(1):87. Epub 2020 Jul 31.

Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1186/s13244-020-00889-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394994PMC
July 2020

Secondary hypertrophic osteoarthropathy in pediatric Hodgkin Lymphoma.

Arthritis Rheumatol 2020 Jul 20. Epub 2020 Jul 20.

The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/art.41445DOI Listing
July 2020

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction.

Nat Commun 2020 06 19;11(1):3150. Epub 2020 Jun 19.

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1038/s41467-020-16819-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305203PMC
June 2020

Gut microbiota in chronic inflammatory disorders: A focus on pediatric inflammatory bowel diseases and juvenile idiopathic arthritis.

Clin Immunol 2020 Jun 9;215:108415. Epub 2020 Apr 9.

Department of Paediatrics, Faculty of Medicine, University of Toronto, Canada; Division of Rheumatology, The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2020.108415DOI Listing
June 2020

The Challenges and Opportunities of Classifying Childhood Arthritis.

Curr Rheumatol Rep 2020 01 11;22(1). Epub 2020 Jan 11.

Departments of Paediatrics and Medicine, Division of Rheumatology, University of Toronto and The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.

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http://dx.doi.org/10.1007/s11926-020-0880-3DOI Listing
January 2020

Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases.

J Clin Invest 2020 Apr;130(4):1669-1682

Translational Autoinflammatory Diseases Section (TADS), NIAID/NIH, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1172/JCI129301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108905PMC
April 2020

Childhood GPA, EGPA, and MPA.

Clin Immunol 2020 02 11;211:108325. Epub 2019 Dec 11.

Departments of Pediatrics and Medicine, University of Toronto, Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2019.108325DOI Listing
February 2020

Initial Results from a Pilot Comparative Effectiveness Study of 3 Methotrexate-based Consensus Treatment Plans for Juvenile Localized Scleroderma.

J Rheumatol 2020 08 15;47(8):1242-1252. Epub 2019 Oct 15.

From the Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack Meridian School of Medicine at Seton Hall University, Nutley, New Jersey; UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania; Duke University School of Medicine, Durham, North Carolina; Boston Children's Hospital, Boston, Massachusetts; Children's Mercy Hospital, Kansas City, Missouri; University of Iowa Carver College of Medicine; University of Iowa Stead Family Children's Hospital, Iowa City, Iowa; Children's Medical Center of Dallas and UT Southwestern, Dallas, Texas; The Ohio State University, Columbus, Ohio; Mayo Clinic, Rochester, Minnesota; University of Colorado-Denver and Children's Hospital Colorado, Denver, Colorado; Rutgers University, School of Public Health, Newark, New Jersey, USA; University of Toronto and The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.190311DOI Listing
August 2020

A 5-year-old girl with recurrent fever.

Paediatr Child Health 2019 Sep 5;24(6):368-370. Epub 2019 Jan 5.

The Hospital for Sick Children.

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http://dx.doi.org/10.1093/pch/pxy184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735584PMC
September 2019

Towards therapeutic drug monitoring of TNF inhibitors for children with juvenile idiopathic arthritis: a scoping review.

Rheumatology (Oxford) 2020 02;59(2):386-397

Division of Rheumatology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/rheumatology/kez285DOI Listing
February 2020

Hallmark trials in ANCA-associated vasculitis (AAV) for the pediatric rheumatologist.

Pediatr Rheumatol Online J 2019 Jun 26;17(1):31. Epub 2019 Jun 26.

Department of Pediatrics, Division of Rheumatology, Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.

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http://dx.doi.org/10.1186/s12969-019-0343-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595671PMC
June 2019

PANDAS/PANS in childhood: Controversies and evidence.

Paediatr Child Health 2019 May 9;24(2):85-91. Epub 2018 Dec 9.

Division of Neurology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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https://academic.oup.com/pch/article/24/2/85/5236858
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http://dx.doi.org/10.1093/pch/pxy145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462125PMC
May 2019

A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency.

J Allergy Clin Immunol 2019 06 13;143(6):2296-2299. Epub 2019 Feb 13.

Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory AMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677392PMC
June 2019

Concurrent chronic recurrent multifocal osteomyelitis and familial Mediterranean fever. A case report.

Clin Exp Rheumatol 2018 Nov-Dec;36(6 Suppl 115):151. Epub 2018 Dec 14.

The Hospital for Sick Children and University of Toronto, Canada.

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March 2019

Pediatric Idiopathic Intervertebral Disc Calcification: Single-Center Series and Review of the Literature.

J Pediatr 2019 03 19;206:212-216. Epub 2018 Nov 19.

Division of Neurosurgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S00223476183156
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http://dx.doi.org/10.1016/j.jpeds.2018.10.058DOI Listing
March 2019

Risk of Serious Infections Associated with Biologic Agents in Juvenile Idiopathic Arthritis: A Systematic Review and Meta-Analyses.

J Pediatr 2019 01 11;204:162-171.e3. Epub 2018 Oct 11.

Division of Rheumatology, The Hospital for Sick Children, Department of Pediatrics and Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jpeds.2018.08.065DOI Listing
January 2019

Toward New Classification Criteria for Juvenile Idiopathic Arthritis: First Steps, Pediatric Rheumatology International Trials Organization International Consensus.

J Rheumatol 2019 02 1;46(2):190-197. Epub 2018 Oct 1.

From Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Giannina Gaslini, Direzione Scientifica; IRCCS Istituto Giannina Gaslini, Clinica Pediatrica e Reumatologia, Pediatric Rheumatology International Trials Organization (PRINTO), and Università degli Studi di Genova; IRCCS Istituto Giannina Gaslini, Servizio di Epidemiologia e Biostatistica, Genoa, Italy; University Children's Hospital, University Medical Center Ljubljana, Department of Allergology, Rheumatology and Clinical Immunology, Ljubljana, Slovenia; Department of Paediatric Rheumatology, Alder Hey Children's National Health Service (NHS) Foundation Trust; Institute of Translational Medicine, University of Liverpool, Liverpool, UK; Hospital General de Mexico, Departamento de Reumatología, Mexico City, Mexico; Hospital Pedro de Elizalde, Rheumatology Section, Buenos Aires, Argentina; Children's Hospital at Montefiore, Albert Einstein College of Medicine, Pediatrics, New Hyde Park, New York; Cincinnati Children's Hospital Medical Center, Division of Rheumatology, Cincinnati, Ohio; Seattle Children's Hospital, Seattle, Washington, USA; Jaslok Hospital and Research Centre, Department of Paediatrics, Mumbai, India; The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, Ontario; British Columbia Children's Hospital, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada; Wilhelmina Children's Hospital, Department of Pediatric Immunology and Rheumatology, Utrecht, the Netherlands.

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http://dx.doi.org/10.3899/jrheum.180168DOI Listing
February 2019

Imaging findings of sterile pyogenic arthritis, pyoderma gangrenosum and acne (PAPA) syndrome: differential diagnosis and review of the literature.

Pediatr Radiol 2019 01 17;49(1):23-36. Epub 2018 Sep 17.

Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00247-018-4246-1DOI Listing
January 2019

New Features for Measuring Disease Activity in Pediatric Localized Scleroderma.

J Rheumatol 2018 12 15;45(12):1680-1688. Epub 2018 Sep 15.

From the Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, Department of Pediatrics, Hackensack; Stevens Institute of Technology, Hoboken, New Jersey, USA; Hospital for Sick Children, Toronto, Ontario, Canada; Texas Scottish Rite Hospital, University of Texas (UT) Southwestern, Dallas, Texas; The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio; Duke University, Durham, North Carolina; Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana; Rockefeller University, New York, New York, USA; Hamburger Zentrum für Kinder- und Jugendrheumatologie, Hamburg, Germany; Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.3899/jrheum.171381DOI Listing
December 2018

Natural history and extracutaneous involvement of congenital morphea: Multicenter retrospective cohort study and literature review.

Pediatr Dermatol 2018 Nov 6;35(6):761-768. Epub 2018 Sep 6.

Section of Dermatology, Division of Paediatric Medicine, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/pde.13605DOI Listing
November 2018

Primary Vasculitis in Childhood: GPA and MPA in Childhood.

Front Pediatr 2018 16;6:226. Epub 2018 Aug 16.

The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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https://www.frontiersin.org/article/10.3389/fped.2018.00226/
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http://dx.doi.org/10.3389/fped.2018.00226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107029PMC
August 2018

Presentation and Disease Course of Childhood-Onset Versus Adult-Onset Takayasu Arteritis.

Arthritis Rheumatol 2019 02 29;71(2):315-323. Epub 2018 Dec 29.

The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/art.40690DOI Listing
February 2019

Recurrent oral ulcerations following heart transplant in a pediatric patient: A diagnostic dilemma.

Pediatr Transplant 2018 11 12;22(7):e13264. Epub 2018 Jul 12.

Division of Hematology and Oncology, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/petr.13264DOI Listing
November 2018

Haploinsufficiency of A20 and other paediatric inflammatory disorders with mucosal involvement.

Curr Opin Rheumatol 2018 09;30(5):506-513

Division of Rheumatology, Departments of Pediatrics and Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://Insights.ovid.com/crossref?an=00002281-900000000-9912
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http://dx.doi.org/10.1097/BOR.0000000000000532DOI Listing
September 2018

Response to: 'A20 haploinsufficiency (HA20): clinical phenotypes and disease course of patients with a newly recognised NF-kB-mediated autoinflammatory disease' by Aeschlimann .

Ann Rheum Dis 2019 05 24;78(5):e36. Epub 2018 Mar 24.

Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/annrheumdis-2018-213359DOI Listing
May 2019

Chemotherapy-Colchicine Interaction in a Child with Familial Mediterranean Fever and Hodgkin Lymphoma.

Mediterr J Hematol Infect Dis 2018 1;10(1):e2018019. Epub 2018 Mar 1.

Division of Hematology/Oncology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://www.mjhid.org/index.php/mjhid/article/view/2018.019
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http://dx.doi.org/10.4084/MJHID.2018.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841933PMC
March 2018

Childhood Takayasu arteritis: disease course and response to therapy.

Arthritis Res Ther 2017 Nov 22;19(1):255. Epub 2017 Nov 22.

Division of Rheumatology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.

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http://dx.doi.org/10.1186/s13075-017-1452-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700506PMC
November 2017

Approche à la fièvre récurrente de l’enfant.

Can Fam Physician 2017 Oct;63(10):e408-e415

Professeur au Département de pédiatrie et au Département de médecine de l'Université de Toronto, et est rhumatologue membre du personnel à la Division de rhumatologie de l'Hospital for Sick Children.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638488PMC
October 2017

Approach to recurrent fever in childhood.

Can Fam Physician 2017 Oct;63(10):756-762

Professor in the Department of Paediatrics and the Department of Medicine at the University of Toronto and a staff rheumatologist in the Division of Rheumatology at The Hospital for Sick Children.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638471PMC
October 2017

A Toddler Presenting with Pulmonary Renal Syndrome.

Case Rep Nephrol Dial 2017 May-Aug;7(2):73-80. Epub 2017 Jun 23.

Division of Nephrology, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1159/000477662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567106PMC
June 2017

Adie Pupil as the Initial Presentation of Localized En Coup de Sabre Scleroderma.

J Rheumatol 2017 07;44(7):1096-1097

Section of Dermatology, The Hospital for Sick Children, and Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.161442DOI Listing
July 2017

Learning the hard way: clinical trials in juvenile idiopathic arthritis.

Ann Rheum Dis 2018 01 25;77(1):1-2. Epub 2017 May 25.

Division of Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1136/annrheumdis-2017-211108DOI Listing
January 2018

Ultrasound-guided steroid tendon sheath injections in juvenile idiopathic arthritis: a 10-year single-center retrospective study.

Pediatr Rheumatol Online J 2017 Apr 11;15(1):22. Epub 2017 Apr 11.

Image Guided Therapy, Department of Diagnostic Imaging, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada.

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http://ped-rheum.biomedcentral.com/articles/10.1186/s12969-0
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http://dx.doi.org/10.1186/s12969-017-0155-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387283PMC
April 2017

Interferon-Stimulated Gene Expression as a Preferred Biomarker for Disease Activity in Aicardi-Goutières Syndrome.

J Interferon Cytokine Res 2017 04 17;37(4):147-152. Epub 2017 Feb 17.

1 Toronto General Research Institute, University Health Network , Toronto, Ontario, Canada .

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http://dx.doi.org/10.1089/jir.2016.0117DOI Listing
April 2017

Physicians' Perspectives on the Diagnosis and Treatment of Chronic Nonbacterial Osteomyelitis.

Int J Rheumatol 2017 10;2017:7694942. Epub 2017 Jan 10.

Pediatrics, Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, USA.

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http://dx.doi.org/10.1155/2017/7694942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259599PMC
January 2017

Arterial dissection in childhood Takayasu Arteritis: not as rare as thought.

Pediatr Rheumatol Online J 2016 Sep 22;14(1):56. Epub 2016 Sep 22.

Division of Rheumatology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1186/s12969-016-0115-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034589PMC
September 2016

Early Onset of Chronic Rheumatic Disease May Lead to Creative Expression: The Stories of Antoni Gaudí and Maud Lewis.

J Rheumatol 2016 07;43(7):1436-43

Division of Rheumatology, Department of Pediatrics and Medicine, The Hospital for Sick Children, and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.151191DOI Listing
July 2016

Pediatric Mixed Connective Tissue Disease.

Curr Rheumatol Rep 2016 May;18(5):28

Division of Rheumatology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada.

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http://dx.doi.org/10.1007/s11926-016-0576-xDOI Listing
May 2016

New discoveries in CRMO: IL-1β, the neutrophil, and the microbiome implicated in disease pathogenesis in Pstpip2-deficient mice.

Semin Immunopathol 2015 Jul 17;37(4):407-12. Epub 2015 Apr 17.

Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, USA,

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http://dx.doi.org/10.1007/s00281-015-0488-2DOI Listing
July 2015

Early aggressive therapy for patients with juvenile idiopathic arthritis: are we there yet?

J Rheumatol 2014 Dec;41(12):2343-6

Professor of Pediatrics and Medicine, University of Toronto, Staff Rheumatologist, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.141051DOI Listing
December 2014

Trying to improve care: the Morbidity and Mortality Conference in a division of rheumatology.

J Rheumatol 2014 Dec 1;41(12):2452-8. Epub 2014 Nov 1.

From the Division of Rheumatology, Department of Pediatrics, McMaster Children's Hospital, McMaster University, Hamilton; Division of Rheumatology, Department of Pediatrics, Department of Medicine, The Hospital for Sick Children; Dalla Lana School of Public Health; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.M. Batthish, MD, Division of Rheumatology, Department of Pediatrics, McMaster Children's Hospital, McMaster University; S.M.L. Tse, MD, Division of Rheumatology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto; B.M. Feldman, MD, Division of Rheumatology, Department of Pediatrics, The Hospital for Sick Children, Dalla Lana School of Public Health, University of Toronto; G.R. Baker, PhD, Institute of Health Policy, Management and Evaluation, University of Toronto; R.M. Laxer, MD, Division of Rheumatology, Departments of Pediatrics and Medicine, The Hospital for Sick Children, University of Toronto.

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http://dx.doi.org/10.3899/jrheum.140203DOI Listing
December 2014

Paediatric rheumatology: A disease activity index for juvenile SpA-a welcome addition.

Nat Rev Rheumatol 2014 Nov 9;10(11):642-4. Epub 2014 Sep 9.

Department of Paediatrics, Division of Rheumatology, The University of Toronto and The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.

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http://dx.doi.org/10.1038/nrrheum.2014.150DOI Listing
November 2014

The new histopathologic classification of ANCA-associated GN and its association with renal outcomes in childhood.

Clin J Am Soc Nephrol 2014 Oct 21;9(10):1684-91. Epub 2014 Aug 21.

Divisions of Nephrology, Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.2215/CJN.01210214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186506PMC
October 2014

Multicentric carpotarsal osteolysis syndrome is caused by only a few domain-specific mutations in MAFB, a negative regulator of RANKL-induced osteoclastogenesis.

Am J Med Genet A 2014 Sep 2;164A(9):2287-93. Epub 2014 Jul 2.

Division of Bone and Mineral Diseases, Washington University School of Medicine at Barnes-Jewish Hospital, St. Louis, Missouri; Center for Metabolic Bone Disease and Molecular Research, Shriners Hospital for Children, St. Louis, Missouri.

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http://dx.doi.org/10.1002/ajmg.a.36641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505615PMC
September 2014

Advances in paediatric rheumatology and translation of research to targeted therapies. Preface.

Best Pract Res Clin Rheumatol 2014 Apr;28(2):173-4

Paediatrics and Medicine, The Hospital for Sick Children, University of Toronto, Canada.

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http://dx.doi.org/10.1016/j.berh.2014.06.001DOI Listing
April 2014

Diagnosis and management of morphea and lichen sclerosus and atrophicus in children.

Pediatr Clin North Am 2014 Apr 27;61(2):309-19. Epub 2013 Dec 27.

Departments of Paediatrics and Medicine, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada.

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http://dx.doi.org/10.1016/j.pcl.2013.11.006DOI Listing
April 2014

Methotrexate: new uses for an old drug.

J Pediatr 2014 Feb 25;164(2):231-6. Epub 2013 Nov 25.

Department of Pediatrics, University of Padua, Padua, Italy.

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http://dx.doi.org/10.1016/j.jpeds.2013.10.029DOI Listing
February 2014

Etanercept (Enbrel) in the treatment of juvenile idiopathic arthritis.

Expert Opin Biol Ther 2013 Nov 26;13(11):1623-30. Epub 2013 Sep 26.

Pediatric Rheumatologist, Western University, Children's Hospital, London Health Sciences Centre, 800 Commissioners Road East, London, Ontario N6A5W9 , Canada +519 685 8138 ; +519 685 8156 ;

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http://dx.doi.org/10.1517/14712598.2013.840580DOI Listing
November 2013

Case 2: Monoarthritis in a four-year-old child.

Paediatr Child Health 2012 Aug;17(7):387-8

Division of Infectious Diseases, The Hospital for Sick Children.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448542PMC
August 2012

Vascular malformation as a cause of limp in a child.

Arthritis Rheum 2013 Sep;65(9):2485

The Hospital for Sick Children and University of Toronto Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/art.38005DOI Listing
September 2013

Later-onset rheumatoid factor negative polyarticular juvenile idiopathic arthritis (JIA): a unique patient group?

Clin Exp Rheumatol 2013 Jul-Aug;31(4):645-52. Epub 2013 Apr 22.

Department of Pediatrics, University of Toronto, Canada.

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October 2013

The challenge of periodic fevers in children.

Paediatr Child Health 2012 Mar;17(3):123

Janeway Children's Health and Rehabilitation Centre, St John's, Newfoundland and Labrador;

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http://www.cpsp.cps.ca/uploads/publications/Highlights-perio
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287087PMC
http://dx.doi.org/10.1093/pch/17.3.123DOI Listing
March 2012

The use of biologic response modifiers in polyarticular-course juvenile idiopathic arthritis: a systematic review.

Semin Arthritis Rheum 2013 Jun 18;42(6):597-618. Epub 2013 Jan 18.

Program of Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1016/j.semarthrit.2012.10.006DOI Listing
June 2013

Reversible splenial lesion syndrome in pediatric systemic lupus erythematosus.

J Rheumatol 2012 Aug;39(8):1698-9

The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.120390
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http://dx.doi.org/10.3899/jrheum.120390DOI Listing
August 2012

Pediatric rheumatology.

Pediatr Clin North Am 2012 Apr 29;59(2):xiii-xiv. Epub 2012 Mar 29.

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http://dx.doi.org/10.1016/j.pcl.2012.03.015DOI Listing
April 2012

New advances in juvenile spondyloarthritis.

Nat Rev Rheumatol 2012 Apr 10;8(5):269-79. Epub 2012 Apr 10.

Division of Rheumatology, The Hospital for Sick Children, 555 University Avenue, University of Toronto, Toronto, ON, M5G 1X8, Canada.

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http://dx.doi.org/10.1038/nrrheum.2012.37DOI Listing
April 2012

Topical imiquimod 5% cream for pediatric plaque morphea: a prospective, multiple-baseline, open-label pilot study.

Dermatology 2011 8;223(4):363-9. Epub 2012 Feb 8.

Section of Dermatology, The Hospital for Sick Children, University of Toronto, Toronto, Ont., Canada.

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http://dx.doi.org/10.1159/000335560DOI Listing
July 2012

Sleep and fatigue and the relationship to pain, disease activity and quality of life in juvenile idiopathic arthritis and juvenile dermatomyositis.

Rheumatology (Oxford) 2011 Nov 25;50(11):2051-60. Epub 2011 Aug 25.

Department of Pediatrics, Technion Institution, Pediatric Department Rheumatology Unit, Technion Faculty of Medicine, Meyer Children’s Hospital of Haifa, Haifa, Israel.

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http://dx.doi.org/10.1093/rheumatology/ker256DOI Listing
November 2011

Brain cavernomas associated with en coup de sabre linear scleroderma: Two case reports.

Pediatr Rheumatol Online J 2011 Jul 29;9:18. Epub 2011 Jul 29.

Department of Pediatrics, Division of Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1186/1546-0096-9-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162908PMC
July 2011

Clinical care of children with sterile bone inflammation.

Curr Opin Rheumatol 2011 Sep;23(5):424-31

Division of Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/BOR.0b013e328349c363DOI Listing
September 2011

En coup de sabre scleroderma and Parry-Romberg syndrome in adolescents: surgical options and patient-related outcomes.

J Rheumatol 2010 Oct 15;37(10):2174-9. Epub 2010 Sep 15.

Section of Dermatology, Division of Paediatric Medicine, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.100062DOI Listing
October 2010

The safety profile of biologic therapies for juvenile idiopathic arthritis.

Nat Rev Rheumatol 2010 Oct 31;6(10):561-71. Epub 2010 Aug 31.

Pediatric Rheumatology Unit, Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem 91031, Israel.

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http://dx.doi.org/10.1038/nrrheum.2010.142DOI Listing
October 2010

Cost-effectiveness of biologics in polyarticular-course juvenile idiopathic arthritis patients unresponsive to disease-modifying antirheumatic drugs.

Arthritis Care Res (Hoboken) 2011 Jan;63(1):111-9

The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/acr.20337DOI Listing
January 2011

Redesigning a morbidity and mortality program in a university-affiliated pediatric anesthesia department.

Jt Comm J Qual Patient Saf 2010 Mar;36(3):117-25

Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto.

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http://dx.doi.org/10.1016/s1553-7250(10)36020-xDOI Listing
March 2010

Lipoatrophy resulting from steroid injection into the temporomandibular joint.

Arthritis Rheum 2009 Nov;60(11):3512

The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/art.24987DOI Listing
November 2009