Publications by authors named "Ronald M Krauss"

100Publications

Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines.

BMC Genomics 2020 Aug 12;21(1):555. Epub 2020 Aug 12.

Department of Pediatrics, University of California San Francisco, Oakland, CA, USA.

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http://dx.doi.org/10.1186/s12864-020-06966-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430882PMC
August 2020

Saturated Fats and Health: A Reassessment and Proposal for Food-Based Recommendations: JACC State-of-the-Art Review.

J Am Coll Cardiol 2020 Aug 17;76(7):844-857. Epub 2020 Jun 17.

Department of Pediatrics, University of California-San Francisco, San Francisco, California; Department of Medicine, University of California-San Francisco, San Francisco, California.

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http://dx.doi.org/10.1016/j.jacc.2020.05.077DOI Listing
August 2020

Public health guidelines should recommend reducing saturated fat consumption as much as possible: YES.

Am J Clin Nutr 2020 07;112(1):13-18

Departments of Pediatrics and Medicine, University of California-San Francisco (UCSF).

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http://dx.doi.org/10.1093/ajcn/nqaa110DOI Listing
July 2020

Public health guidelines should recommend reducing saturated fat consumption as much as possible: Debate Consensus.

Am J Clin Nutr 2020 07;112(1):25-26

Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA.

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http://dx.doi.org/10.1093/ajcn/nqaa134DOI Listing
July 2020

Public health guidelines should recommend reducing saturated fat consumption as much as possible: NO.

Am J Clin Nutr 2020 07;112(1):19-24

Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA.

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http://dx.doi.org/10.1093/ajcn/nqaa111DOI Listing
July 2020

Lipoprotein Particle Predictors of Arterial Stiffness after 17 Years of Follow Up: The Malmö Diet and Cancer Study.

Int J Vasc Med 2020 28;2020:4219180. Epub 2020 Apr 28.

Department of Cardiology, Children's National Hospital, Washington D.C., USA.

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http://dx.doi.org/10.1155/2020/4219180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204174PMC
April 2020

Comparison of nonfasting and fasting lipoprotein subfractions and size in 15,397 apparently healthy individuals: An analysis from the VITamin D and OmegA-3 TriaL.

J Clin Lipidol 2020 Mar - Apr;14(2):241-251. Epub 2020 Feb 21.

Center for Lipid Metabolomics, Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2020.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166180PMC
February 2020

A Randomized Study of the Effect of Replacing Sugar-Sweetened Soda by Reduced Fat Milk on Cardiometabolic Health in Male Adolescent Soda Drinkers.

Nutrients 2020 Feb 4;12(2). Epub 2020 Feb 4.

Children's Hospital Oakland Research Institute; 5700 Martin Luther King Jr. Way, Oakland, CA 94609, USA.

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http://dx.doi.org/10.3390/nu12020405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071288PMC
February 2020

Expanding Precompetitive Multisector Collaborations to Advance Drug Development and Pharmacogenomics.

Clin Pharmacol Ther 2020 01 27;107(1):96-101. Epub 2019 Nov 27.

Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1002/cpt.1691DOI Listing
January 2020

Lifestyle factors and high-risk atherosclerosis: Pathways and mechanisms beyond traditional risk factors.

Eur J Prev Cardiol 2020 Mar 13;27(4):394-406. Epub 2019 Aug 13.

Technical University of Munich, School of Medicine, Department of Prevention, Rehabilitation and Sports Medicine, Germany.

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http://journals.sagepub.com/doi/10.1177/2047487319869400
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http://dx.doi.org/10.1177/2047487319869400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065445PMC
March 2020

Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation.

Stem Cell Res 2019 05 10;37:101434. Epub 2019 Apr 10.

Children's Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2019.101434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570500PMC
May 2019

Low plasma adropin concentrations increase risks of weight gain and metabolic dysregulation in response to a high-sugar diet in male nonhuman primates.

J Biol Chem 2019 06 15;294(25):9706-9719. Epub 2019 Apr 15.

the Department of Molecular Biosciences, School of Veterinary Medicine and Department of Nutrition, University of California, Davis, Davis, California 95616,

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http://dx.doi.org/10.1074/jbc.RA119.007528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597842PMC
June 2019

Low-Density Lipoprotein Particle Size Subfractions and Cerebral Amyloidosis.

J Alzheimers Dis 2019 ;68(3):983-990

Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.3233/JAD-181252DOI Listing
August 2020

Fructose-induced hypertriglyceridemia in rhesus macaques is attenuated with fish oil or ApoC3 RNA interference.

J Lipid Res 2019 04 5;60(4):805-818. Epub 2019 Feb 5.

Department of Molecular Biosciences, School of Veterinary Medicine, California National Primate Research Center, and Department of Nutrition, University of California, Davis, CA

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http://dx.doi.org/10.1194/jlr.M089508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446715PMC
April 2019

Single-molecule 3D imaging of human plasma intermediate-density lipoproteins reveals a polyhedral structure.

Biochim Biophys Acta Mol Cell Biol Lipids 2019 03 14;1864(3):260-270. Epub 2018 Dec 14.

The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13881981183037
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http://dx.doi.org/10.1016/j.bbalip.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409128PMC
March 2019

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Authors:
Symen Ligthart Ahmad Vaez Urmo Võsa Maria G Stathopoulou Paul S de Vries Bram P Prins Peter J Van der Most Toshiko Tanaka Elnaz Naderi Lynda M Rose Ying Wu Robert Karlsson Maja Barbalic Honghuang Lin René Pool Gu Zhu Aurélien Macé Carlo Sidore Stella Trompet Massimo Mangino Maria Sabater-Lleal John P Kemp Ali Abbasi Tim Kacprowski Niek Verweij Albert V Smith Tao Huang Carola Marzi Mary F Feitosa Kurt K Lohman Marcus E Kleber Yuri Milaneschi Christian Mueller Mahmudul Huq Efthymia Vlachopoulou Leo-Pekka Lyytikäinen Christopher Oldmeadow Joris Deelen Markus Perola Jing Hua Zhao Bjarke Feenstra Marzyeh Amini Jari Lahti Katharina E Schraut Myriam Fornage Bhoom Suktitipat Wei-Min Chen Xiaohui Li Teresa Nutile Giovanni Malerba Jian'an Luan Tom Bak Nicholas Schork Fabiola Del Greco M Elisabeth Thiering Anubha Mahajan Riccardo E Marioni Evelin Mihailov Joel Eriksson Ayse Bilge Ozel Weihua Zhang Maria Nethander Yu-Ching Cheng Stella Aslibekyan Wei Ang Ilaria Gandin Loïc Yengo Laura Portas Charles Kooperberg Edith Hofer Kumar B Rajan Claudia Schurmann Wouter den Hollander Tarunveer S Ahluwalia Jing Zhao Harmen H M Draisma Ian Ford Nicholas Timpson Alexander Teumer Hongyan Huang Simone Wahl YongMei Liu Jie Huang Hae-Won Uh Frank Geller Peter K Joshi Lisa R Yanek Elisabetta Trabetti Benjamin Lehne Diego Vozzi Marie Verbanck Ginevra Biino Yasaman Saba Ingrid Meulenbelt Jeff R O'Connell Markku Laakso Franco Giulianini Patrik K E Magnusson Christie M Ballantyne Jouke Jan Hottenga Grant W Montgomery Fernando Rivadineira Rico Rueedi Maristella Steri Karl-Heinz Herzig David J Stott Cristina Menni Mattias Frånberg Beate St Pourcain Stephan B Felix Tune H Pers Stephan J L Bakker Peter Kraft Annette Peters Dhananjay Vaidya Graciela Delgado Johannes H Smit Vera Großmann Juha Sinisalo Ilkka Seppälä Stephen R Williams Elizabeth G Holliday Matthijs Moed Claudia Langenberg Katri Räikkönen Jingzhong Ding Harry Campbell Michele M Sale Yii-Der I Chen Alan L James Daniela Ruggiero Nicole Soranzo Catharina A Hartman Erin N Smith Gerald S Berenson Christian Fuchsberger Dena Hernandez Carla M T Tiesler Vilmantas Giedraitis David Liewald Krista Fischer Dan Mellström Anders Larsson Yunmei Wang William R Scott Matthias Lorentzon John Beilby Kathleen A Ryan Craig E Pennell Dragana Vuckovic Beverly Balkau Maria Pina Concas Reinhold Schmidt Carlos F Mendes de Leon Erwin P Bottinger Margreet Kloppenburg Lavinia Paternoster Michael Boehnke A W Musk Gonneke Willemsen David M Evans Pamela A F Madden Mika Kähönen Zoltán Kutalik Magdalena Zoledziewska Ville Karhunen Stephen B Kritchevsky Naveed Sattar Genevieve Lachance Robert Clarke Tamara B Harris Olli T Raitakari John R Attia Diana van Heemst Eero Kajantie Rossella Sorice Giovanni Gambaro Robert A Scott Andrew A Hicks Luigi Ferrucci Marie Standl Cecilia M Lindgren John M Starr Magnus Karlsson Lars Lind Jun Z Li John C Chambers Trevor A Mori Eco J C N de Geus Andrew C Heath Nicholas G Martin Juha Auvinen Brendan M Buckley Anton J M de Craen Melanie Waldenberger Konstantin Strauch Thomas Meitinger Rodney J Scott Mark McEvoy Marian Beekman Cristina Bombieri Paul M Ridker Karen L Mohlke Nancy L Pedersen Alanna C Morrison Dorret I Boomsma John B Whitfield David P Strachan Albert Hofman Peter Vollenweider Francesco Cucca Marjo-Riitta Jarvelin J Wouter Jukema Tim D Spector Anders Hamsten Tanja Zeller André G Uitterlinden Matthias Nauck Vilmundur Gudnason Lu Qi Harald Grallert Ingrid B Borecki Jerome I Rotter Winfried März Philipp S Wild Marja-Liisa Lokki Michael Boyle Veikko Salomaa Mads Melbye Johan G Eriksson James F Wilson Brenda W J H Penninx Diane M Becker Bradford B Worrall Greg Gibson Ronald M Krauss Marina Ciullo Gianluigi Zaza Nicholas J Wareham Albertine J Oldehinkel Lyle J Palmer Sarah S Murray Peter P Pramstaller Stefania Bandinelli Joachim Heinrich Erik Ingelsson Ian J Deary Reedik Mägi Liesbeth Vandenput Pim van der Harst Karl C Desch Jaspal S Kooner Claes Ohlsson Caroline Hayward Terho Lehtimäki Alan R Shuldiner Donna K Arnett Lawrence J Beilin Antonietta Robino Philippe Froguel Mario Pirastu Tine Jess Wolfgang Koenig Ruth J F Loos Denis A Evans Helena Schmidt George Davey Smith P Eline Slagboom Gudny Eiriksdottir Andrew P Morris Bruce M Psaty Russell P Tracy Ilja M Nolte Eric Boerwinkle Sophie Visvikis-Siest Alex P Reiner Myron Gross Joshua C Bis Lude Franke Oscar H Franco Emelia J Benjamin Daniel I Chasman Josée Dupuis Harold Snieder Abbas Dehghan Behrooz Z Alizadeh

Am J Hum Genet 2018 11;103(5):691-706

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183032
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http://dx.doi.org/10.1016/j.ajhg.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218410PMC
November 2018

Metagenomic Insights into the Degradation of Resistant Starch by Human Gut Microbiota.

Appl Environ Microbiol 2018 12 15;84(23). Epub 2018 Nov 15.

Center for Microbial Ecology, Michigan State University, East Lansing, Michigan, USA

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http://aem.asm.org/lookup/doi/10.1128/AEM.01562-18
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http://dx.doi.org/10.1128/AEM.01562-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238065PMC
December 2018

ZNF542P is a pseudogene associated with LDL response to simvastatin treatment.

Sci Rep 2018 08 20;8(1):12443. Epub 2018 Aug 20.

Children's Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA, 94609, USA.

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http://dx.doi.org/10.1038/s41598-018-30859-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102286PMC
August 2018

Dietary fat and cardiometabolic health: evidence, controversies, and consensus for guidance.

BMJ 2018 Jun 13;361:k2139. Epub 2018 Jun 13.

Departments of Nutrition and Epidemiology, Harvard T H Chan School of Public Health, Harvard University, Boston, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053258PMC
http://dx.doi.org/10.1136/bmj.k2139DOI Listing
June 2018

Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content.

PLoS Biol 2018 04 16;16(4):e2002907. Epub 2018 Apr 16.

Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.2002907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919692PMC
April 2018

PCSK9 deficiency reduces atherosclerosis, apolipoprotein B secretion, and endothelial dysfunction.

J Lipid Res 2018 02 27;59(2):207-223. Epub 2017 Nov 27.

Research Center for Human Genetics, Brown Foundation Institute of Molecular Medicine University of Texas Health Science Center at Houston, Houston, TX

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http://dx.doi.org/10.1194/jlr.M078360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794417PMC
February 2018

Assessing the mechanisms of cholesteryl ester transfer protein inhibitors.

Biochim Biophys Acta Mol Cell Biol Lipids 2017 Dec 12;1862(12):1606-1617. Epub 2017 Sep 12.

Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2017.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239860PMC
December 2017

Changes in low-density lipoprotein size phenotypes associate with changes in apolipoprotein C-III glycoforms after dietary interventions.

J Clin Lipidol 2017 Jan - Feb;11(1):224-233.e2. Epub 2016 Dec 28.

Department of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2016.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790205PMC
October 2017

Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies.

Circ Cardiovasc Genet 2017 Jan;10(1)

From the Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory (Å.K.H., S.G., E.I.) and Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory (J.K.S.), Uppsala University, Sweden; Cardiovascular Medicine unit, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden (Å.K.H.) Framingham Heart Study, MA (M.M.M., R.J., C.Y., C.L., T.H., S.D., L.A.C., D.L.); Department of Biostatistics (C.L., L.A.C., S.D.), Boston University, MA; Boston University, MA (M.M.M.); Department of Cardiology, Boston Children's Hospital, MA (M.M.M.); Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (M.M.M., R.J., C.Y., C.L., T.H., D.L.); Centre for Cognitive Ageing and Cognitive Epidemiology (R.E.M., J.M.S., I.J.D.), Medical Genetics Section, Centre for Genomics and Experimental Medicine, Institute of Genetics and Molecular Medicine (R.E.M.), Alzheimer Scotland Dementia Research Centre (J.M.S.), and Department of Psychology (I.J.D.), University of Edinburgh, United Kingdom; Queensland Brain Institute, The University of Queensland, Brisbane, Australia (R.E.M., A.F.M., S.S.); Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia (S.S., A.F.M.); Hebrew Senior Life, Harvard Medical School, Boston, MA (R.J.); Department of Epidemiology, School of Public Health (M.R.I.) and Department of Biostatistics, Section on Statistical Genetics (D.Z.), University of Alabama at Birmingham; Department of Biostatistics, Harvard School of Public Health, Boston, MA (L. Liang); William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (P.D.); Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia (P.D.); Department of Twin Research and Genetic Epidemiology, King's College London, United Kingdom (T.D.S.); Deparment of Medical Sciences, Cardiovascular Epidemiology, Uppsala University Hospital, Sweden (J.S., L.L.); Children's Hospital Oakland Research Institute, CA (R.M.K.); College of Public Health, University of Kentucky, Lexington (D.K.A.); and Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, CA (E.I.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331877PMC
January 2017

Effects of a very high saturated fat diet on LDL particles in adults with atherogenic dyslipidemia: A randomized controlled trial.

PLoS One 2017 6;12(2):e0170664. Epub 2017 Feb 6.

Children's Hospital Oakland Research Institute, Oakland, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170664PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293238PMC
August 2017

Pharmacometabolomic signature links simvastatin therapy and insulin resistance.

Metabolomics 2017 01 23;13. Epub 2016 Dec 23.

Department of Internal Medicine; Department of Psychiatry and Behavioral Sciences, Duke Institute for Brain Sciences, Duke University Medical Center, Durham, NC, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931366PMC
http://dx.doi.org/10.1007/s11306-016-1141-3DOI Listing
January 2017

Which cheese to choose?

Am J Clin Nutr 2016 10 14;104(4):953-954. Epub 2016 Sep 14.

Children's Hospital Oakland Research Institute, Oakland, CA

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http://dx.doi.org/10.3945/ajcn.116.143305DOI Listing
October 2016

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.

Authors:
Georg B Ehret Teresa Ferreira Daniel I Chasman Anne U Jackson Ellen M Schmidt Toby Johnson Gudmar Thorleifsson Jian'an Luan Lousie A Donnelly Stavroula Kanoni Ann-Kristin Petersen Vasyl Pihur Rona J Strawbridge Dmitry Shungin Maria F Hughes Osorio Meirelles Marika Kaakinen Nabila Bouatia-Naji Kati Kristiansson Sonia Shah Marcus E Kleber Xiuqing Guo Leo-Pekka Lyytikäinen Cristiano Fava Niclas Eriksson Ilja M Nolte Patrik K Magnusson Elias L Salfati Loukianos S Rallidis Elizabeth Theusch Andrew J P Smith Lasse Folkersen Kate Witkowska Tune H Pers Roby Joehanes Stuart K Kim Lazaros Lataniotis Rick Jansen Andrew D Johnson Helen Warren Young Jin Kim Wei Zhao Ying Wu Bamidele O Tayo Murielle Bochud Devin Absher Linda S Adair Najaf Amin Dan E Arking Tomas Axelsson Damiano Baldassarre Beverley Balkau Stefania Bandinelli Michael R Barnes Inês Barroso Stephen Bevan Joshua C Bis Gyda Bjornsdottir Michael Boehnke Eric Boerwinkle Lori L Bonnycastle Dorret I Boomsma Stefan R Bornstein Morris J Brown Michel Burnier Claudia P Cabrera John C Chambers I-Shou Chang Ching-Yu Cheng Peter S Chines Ren-Hua Chung Francis S Collins John M Connell Angela Döring Jean Dallongeville John Danesh Ulf de Faire Graciela Delgado Anna F Dominiczak Alex S F Doney Fotios Drenos Sarah Edkins John D Eicher Roberto Elosua Stefan Enroth Jeanette Erdmann Per Eriksson Tonu Esko Evangelos Evangelou Alun Evans Tove Fall Martin Farrall Janine F Felix Jean Ferrières Luigi Ferrucci Myriam Fornage Terrence Forrester Nora Franceschini Oscar H Franco Duran Anders Franco-Cereceda Ross M Fraser Santhi K Ganesh He Gao Karl Gertow Francesco Gianfagna Bruna Gigante Franco Giulianini Anuj Goel Alison H Goodall Mark O Goodarzi Mathias Gorski Jürgen Gräßler Christopher Groves Vilmundur Gudnason Ulf Gyllensten Göran Hallmans Anna-Liisa Hartikainen Maija Hassinen Aki S Havulinna Caroline Hayward Serge Hercberg Karl-Heinz Herzig Andrew A Hicks Aroon D Hingorani Joel N Hirschhorn Albert Hofman Jostein Holmen Oddgeir Lingaas Holmen Jouke-Jan Hottenga Phil Howard Chao A Hsiung Steven C Hunt M Arfan Ikram Thomas Illig Carlos Iribarren Richard A Jensen Mika Kähönen Hyun Kang Sekar Kathiresan Brendan J Keating Kay-Tee Khaw Yun Kyoung Kim Eric Kim Mika Kivimaki Norman Klopp Genovefa Kolovou Pirjo Komulainen Jaspal S Kooner Gulum Kosova Ronald M Krauss Diana Kuh Zoltan Kutalik Johanna Kuusisto Kirsti Kvaløy Timo A Lakka Nanette R Lee I-Te Lee Wen-Jane Lee Daniel Levy Xiaohui Li Kae-Woei Liang Honghuang Lin Li Lin Jaana Lindström Stéphane Lobbens Satu Männistö Gabriele Müller Martina Müller-Nurasyid François Mach Hugh S Markus Eirini Marouli Mark I McCarthy Colin A McKenzie Pierre Meneton Cristina Menni Andres Metspalu Vladan Mijatovic Leena Moilanen May E Montasser Andrew D Morris Alanna C Morrison Antonella Mulas Ramaiah Nagaraja Narisu Narisu Kjell Nikus Christopher J O'Donnell Paul F O'Reilly Ken K Ong Fred Paccaud Cameron D Palmer Afshin Parsa Nancy L Pedersen Brenda W Penninx Markus Perola Annette Peters Neil Poulter Peter P Pramstaller Bruce M Psaty Thomas Quertermous Dabeeru C Rao Asif Rasheed N William N W R Rayner Frida Renström Rainer Rettig Kenneth M Rice Robert Roberts Lynda M Rose Jacques Rossouw Nilesh J Samani Serena Sanna Jouko Saramies Heribert Schunkert Sylvain Sebert Wayne H-H Sheu Young-Ah Shin Xueling Sim Johannes H Smit Albert V Smith Maria X Sosa Tim D Spector Alena Stančáková Alice Stanton Kathleen E Stirrups Heather M Stringham Johan Sundstrom Amy J Swift Ann-Christine Syvänen E-Shyong Tai Toshiko Tanaka Kirill V Tarasov Alexander Teumer Unnur Thorsteinsdottir Martin D Tobin Elena Tremoli Andre G Uitterlinden Matti Uusitupa Ahmad Vaez Dhananjay Vaidya Cornelia M van Duijn Erik P A van Iperen Ramachandran S Vasan Germaine C Verwoert Jarmo Virtamo Veronique Vitart Benjamin F Voight Peter Vollenweider Aline Wagner Louise V Wain Nicholas J Wareham Hugh Watkins Alan B Weder Harm-Jan Westra Rainford Wilks Tom Wilsgaard James F Wilson Tien Y Wong Tsun-Po Yang Jie Yao Loic Yengo Weihua Zhang Jing Hua Zhao Xiaofeng Zhu Pascal Bovet Richard S Cooper Karen L Mohlke Danish Saleheen Jong-Young Lee Paul Elliott Hinco J Gierman Cristen J Willer Lude Franke G Kees Hovingh Kent D Taylor George Dedoussis Peter Sever Andrew Wong Lars Lind Themistocles L Assimes Inger Njølstad Peter Eh Schwarz Claudia Langenberg Harold Snieder Mark J Caulfield Olle Melander Markku Laakso Juha Saltevo Rainer Rauramaa Jaakko Tuomilehto Erik Ingelsson Terho Lehtimäki Kristian Hveem Walter Palmas Winfried März Meena Kumari Veikko Salomaa Yii-Der I Chen Jerome I Rotter Philippe Froguel Marjo-Riitta Jarvelin Edward G Lakatta Kari Kuulasmaa Paul W Franks Anders Hamsten H-Erich Wichmann Colin N A Palmer Kari Stefansson Paul M Ridker Ruth J F Loos Aravinda Chakravarti Panos Deloukas Andrew P Morris Christopher Newton-Cheh Patricia B Munroe

Nat Genet 2016 10 12;48(10):1171-1184. Epub 2016 Sep 12.

Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK.

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http://dx.doi.org/10.1038/ng.3667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042863PMC
October 2016

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.

J Med Genet 2016 12 1;53(12):835-845. Epub 2016 Sep 1.

Department of Atherosclerosis Research, Children's Hospital Oakland Research Institute, Oakland, California, USA.

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http://dx.doi.org/10.1136/jmedgenet-2016-103966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309131PMC
December 2016

Polyhedral 3D structure of human plasma very low density lipoproteins by individual particle cryo-electron tomography1.

J Lipid Res 2016 10 18;57(10):1879-1888. Epub 2016 Aug 18.

Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036368PMC
http://dx.doi.org/10.1194/jlr.M070375DOI Listing
October 2016

The early years of lipoprotein research: from discovery to clinical application.

J Lipid Res 2016 10 29;57(10):1771-1777. Epub 2016 Jul 29.

Children's Hospital Oakland Research Institute, Oakland, CA 94609-1673

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036374PMC
http://dx.doi.org/10.1194/jlr.R069575DOI Listing
October 2016

Diet, lipids, and cardiovascular disease.

Curr Opin Lipidol 2016 08;27(4):323-8

Children's Hospital Oakland Research Institute, Oakland, California, USA.

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http://dx.doi.org/10.1097/MOL.0000000000000310DOI Listing
August 2016

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.

Authors:
Ching-Ti Liu Sridharan Raghavan Nisa Maruthur Edmond Kato Kabagambe Jaeyoung Hong Maggie C Y Ng Marie-France Hivert Yingchang Lu Ping An Amy R Bentley Anne M Drolet Kyle J Gaulton Xiuqing Guo Loren L Armstrong Marguerite R Irvin Man Li Leonard Lipovich Denis V Rybin Kent D Taylor Charles Agyemang Nicholette D Palmer Brian E Cade Wei-Min Chen Marco Dauriz Joseph A C Delaney Todd L Edwards Daniel S Evans Michele K Evans Leslie A Lange Aaron Leong Jingmin Liu Yongmei Liu Uma Nayak Sanjay R Patel Bianca C Porneala Laura J Rasmussen-Torvik Marieke B Snijder Sarah C Stallings Toshiko Tanaka Lisa R Yanek Wei Zhao Diane M Becker Lawrence F Bielak Mary L Biggs Erwin P Bottinger Donald W Bowden Guanjie Chen Adolfo Correa David J Couper Dana C Crawford Mary Cushman John D Eicher Myriam Fornage Nora Franceschini Yi-Ping Fu Mark O Goodarzi Omri Gottesman Kazuo Hara Tamara B Harris Richard A Jensen Andrew D Johnson Min A Jhun Andrew J Karter Margaux F Keller Abel N Kho Jorge R Kizer Ronald M Krauss Carl D Langefeld Xiaohui Li Jingling Liang Simin Liu William L Lowe Thomas H Mosley Kari E North Jennifer A Pacheco Patricia A Peyser Alan L Patrick Kenneth M Rice Elizabeth Selvin Mario Sims Jennifer A Smith Salman M Tajuddin Dhananjay Vaidya Mary P Wren Jie Yao Xiaofeng Zhu Julie T Ziegler Joseph M Zmuda Alan B Zonderman Aeilko H Zwinderman Adebowale Adeyemo Eric Boerwinkle Luigi Ferrucci M Geoffrey Hayes Sharon L R Kardia Iva Miljkovic James S Pankow Charles N Rotimi Michele M Sale Lynne E Wagenknecht Donna K Arnett Yii-Der Ida Chen Michael A Nalls Michael A Province W H Linda Kao David S Siscovick Bruce M Psaty James G Wilson Ruth J F Loos Josée Dupuis Stephen S Rich Jose C Florez Jerome I Rotter Andrew P Morris James B Meigs

Am J Hum Genet 2016 Jul 16;99(1):56-75. Epub 2016 Jun 16.

Division of General Internal Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005440PMC
July 2016

Does Milk Consumption Contribute to Cardiometabolic Health and Overall Diet Quality?

Can J Cardiol 2016 08 12;32(8):1026-32. Epub 2016 Jan 12.

Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, and Department of Kinesiology, Faculty of Medicine, Université Laval, Québec City, Québec, Canada.

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http://dx.doi.org/10.1016/j.cjca.2015.12.033DOI Listing
August 2016

Prepregnancy Adverse Lipid Profile and Subsequent Risk of Gestational Diabetes.

J Clin Endocrinol Metab 2016 07 5;101(7):2721-7. Epub 2016 Apr 5.

Division of Research (E.S.H., F.X., S.B.S., A.F., C.P.Q., M.M.H.), Kaiser Permanente Northern California, Oakland, California 94612; and Children's Hospital Oakland Research Institute (R.M.K.), Oakland, California 94609.

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http://dx.doi.org/10.1210/jc.2015-3904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929836PMC
July 2016

PharmGKB summary: very important pharmacogene information for RYR1.

Pharmacogenet Genomics 2016 Mar;26(3):138-44

Departments of aGenetics bBioengineering, Stanford University, Stanford cChildren's Hospital Oakland Research Institute and UCSF, Oakland, California dDepartment of Medicine, University of North Dakota, Fargo, North Dakota eIMAGENETICS, Sanford Healthcare, Sioux Falls, South Dakota, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738161PMC
March 2016

Vaccenic acid and trans fatty acid isomers from partially hydrogenated oil both adversely affect LDL cholesterol: a double-blind, randomized controlled trial.

Am J Clin Nutr 2015 Dec 11;102(6):1339-46. Epub 2015 Nov 11.

USDA, Agricultural Research Service, Beltsville Human Nutrition Research Center, Beltsville, MD;

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http://dx.doi.org/10.3945/ajcn.115.116129DOI Listing
December 2015

Proprotein convertase subtilisin/kexin type 9 inhibition: a new therapeutic mechanism for reducing cardiovascular disease risk.

Circulation 2015 Oct;132(17):1648-66

From Children's Hospital Oakland Research Institute, CA (N.B., R.M.K.); Touro University, College of Pharmacy, Vallejo, CA (N.B., Y.D., A.F.); and University of California, San Francisco (B.A.P.P., R.M.K.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.016080DOI Listing
October 2015

Association study of androgen signaling pathway genes in polycystic ovary syndrome.

Fertil Steril 2016 Feb 20;105(2):467-73.e4. Epub 2015 Oct 20.

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2015.09.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744098PMC
February 2016

Endogenous Sex Steroid Hormones, Lipid Subfractions, and Ectopic Adiposity in Asian Indians.

Metab Syndr Relat Disord 2015 Dec 2;13(10):445-52. Epub 2015 Oct 2.

8 Department of Medicine, University of California , San Francisco, California.

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http://dx.doi.org/10.1089/met.2015.0063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696444PMC
December 2015

Atherogenic Lipoprotein Subfractions Determined by Ion Mobility and First Cardiovascular Events After Random Allocation to High-Intensity Statin or Placebo: The Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) Trial.

Circulation 2015 Dec 25;132(23):2220-9. Epub 2015 Sep 25.

From the Divisions of Preventive (S.M., R.J.G., P.MR.) and Cardiovascular Medicine (S.M., P.MR.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Quest Diagnostics, Alameda, CA (M.P.C., J.W., Z.C., C.M.R.); Cholesterol, Genetics, and Heart Disease Institute, Carmel, CA (H.R.S.); and Children's Hospital Oakland Research Institute, Oakland, CA (R.M.K.).

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December 2015

Saturated Fats Versus Polyunsaturated Fats Versus Carbohydrates for Cardiovascular Disease Prevention and Treatment.

Annu Rev Nutr 2015 ;35:517-43

Atherosclerosis Research Program, Children's Hospital Oakland Research Institute, Oakland, California 94609; email: ,

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http://dx.doi.org/10.1146/annurev-nutr-071714-034449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744652PMC
April 2016

Individual and Combined Associations of Genetic Variants in CYP3A4, CYP3A5, and SLCO1B1 With Simvastatin and Simvastatin Acid Plasma Concentrations.

J Cardiovasc Pharmacol 2015 Jul;66(1):80-5

*Department of Pharmacology, Center for Pharmacogenomics, The Ohio State University Wexner Medical Center, Columbus, OH; †Children's Hospital Oakland Research Institute, Oakland, CA; ‡Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, and §Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA; and ‖Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503374PMC
July 2015

A multicomponent nutrient bar promotes weight loss and improves dyslipidemia and insulin resistance in the overweight/obese: chronic inflammation blunts these improvements.

FASEB J 2015 Aug 21;29(8):3287-301. Epub 2015 Apr 21.

*Nutrition and Metabolism Center, Children's Hospital Oakland Research Institute, Oakland, California, USA; Children's National Medical Center, Washington, DC, USA; and Processed Foods Research Unit, U.S. Department of Agriculture-Agricultural Research Service-Western Regional Research Center, Albany, California, USA.

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August 2015

A multivariate genome-wide association analysis of 10 LDL subfractions, and their response to statin treatment, in 1868 Caucasians.

PLoS One 2015 21;10(4):e0120758. Epub 2015 Apr 21.

Department of Human Genetics, University of Chicago, Chicago, IL, USA; Department of Statistics, University of Chicago, Chicago, IL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405269PMC
April 2016

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.

Authors:
Iris Postmus Stella Trompet Harshal A Deshmukh Michael R Barnes Xiaohui Li Helen R Warren Daniel I Chasman Kaixin Zhou Benoit J Arsenault Louise A Donnelly Kerri L Wiggins Christy L Avery Paula Griffin QiPing Feng Kent D Taylor Guo Li Daniel S Evans Albert V Smith Catherine E de Keyser Andrew D Johnson Anton J M de Craen David J Stott Brendan M Buckley Ian Ford Rudi G J Westendorp P Eline Slagboom Naveed Sattar Patricia B Munroe Peter Sever Neil Poulter Alice Stanton Denis C Shields Eoin O'Brien Sue Shaw-Hawkins Y-D Ida Chen Deborah A Nickerson Joshua D Smith Marie Pierre Dubé S Matthijs Boekholdt G Kees Hovingh John J P Kastelein Paul M McKeigue John Betteridge Andrew Neil Paul N Durrington Alex Doney Fiona Carr Andrew Morris Mark I McCarthy Leif Groop Emma Ahlqvist Joshua C Bis Kenneth Rice Nicholas L Smith Thomas Lumley Eric A Whitsel Til Stürmer Eric Boerwinkle Julius S Ngwa Christopher J O'Donnell Ramachandran S Vasan Wei-Qi Wei Russell A Wilke Ching-Ti Liu Fangui Sun Xiuqing Guo Susan R Heckbert Wendy Post Nona Sotoodehnia Alice M Arnold Jeanette M Stafford Jingzhong Ding David M Herrington Stephen B Kritchevsky Gudny Eiriksdottir Leonore J Launer Tamara B Harris Audrey Y Chu Franco Giulianini Jean G MacFadyen Bryan J Barratt Fredrik Nyberg Bruno H Stricker André G Uitterlinden Albert Hofman Fernando Rivadeneira Valur Emilsson Oscar H Franco Paul M Ridker Vilmundur Gudnason Yongmei Liu Joshua C Denny Christie M Ballantyne Jerome I Rotter L Adrienne Cupples Bruce M Psaty Colin N A Palmer Jean-Claude Tardif Helen M Colhoun Graham Hitman Ronald M Krauss J Wouter Jukema Mark J Caulfield

Nat Commun 2014 Oct 28;5:5068. Epub 2014 Oct 28.

1] NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London EC1M 6BQ, UK [2] Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London EC1M6BQ, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220464PMC
October 2014

Further investigation in europeans of susceptibility variants for polycystic ovary syndrome discovered in genome-wide association studies of Chinese individuals.

J Clin Endocrinol Metab 2015 Jan;100(1):E182-6

Department of Obstetrics and Gynecology (M.A.B.), David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California 90095; Division of Endocrinology, Diabetes, and Metabolism (M.R.J., M.O.G.), Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048; Institute for Translational Genomics and Population Sciences and Department of Pediatrics (J.I.R.), Los Angeles Biomedical Research Institute at Harbor-University of California, Los Angeles, Medical Center, Torrance, California 90502; Children's Hospital of Oakland Research Institute (R.M.K.), Oakland, California 94609; Department of Obstetrics and Gynecology (R.S.L.), Pennsylvania State College of Medicine, Hershey, Pennsylvania 17033; and Departments of Obstetrics and Gynecology and Medicine (R.A.), Medical College of Georgia, Georgia Regents University, Augusta, Georgia 30912.

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http://dx.doi.org/10.1210/jc.2014-2689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283012PMC
January 2015

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

Authors:
Daniel I Swerdlow David Preiss Karoline B Kuchenbaecker Michael V Holmes Jorgen E L Engmann Tina Shah Reecha Sofat Stefan Stender Paul C D Johnson Robert A Scott Maarten Leusink Niek Verweij Stephen J Sharp Yiran Guo Claudia Giambartolomei Christina Chung Anne Peasey Antoinette Amuzu KaWah Li Jutta Palmen Philip Howard Jackie A Cooper Fotios Drenos Yun R Li Gordon Lowe John Gallacher Marlene C W Stewart Ioanna Tzoulaki Sarah G Buxbaum Daphne L van der A Nita G Forouhi N Charlotte Onland-Moret Yvonne T van der Schouw Renate B Schnabel Jaroslav A Hubacek Ruzena Kubinova Migle Baceviciene Abdonas Tamosiunas Andrzej Pajak Roman Topor-Madry Urszula Stepaniak Sofia Malyutina Damiano Baldassarre Bengt Sennblad Elena Tremoli Ulf de Faire Fabrizio Veglia Ian Ford J Wouter Jukema Rudi G J Westendorp Gert Jan de Borst Pim A de Jong Ale Algra Wilko Spiering Anke H Maitland-van der Zee Olaf H Klungel Anthonius de Boer Pieter A Doevendans Charles B Eaton Jennifer G Robinson David Duggan John Kjekshus John R Downs Antonio M Gotto Anthony C Keech Roberto Marchioli Gianni Tognoni Peter S Sever Neil R Poulter David D Waters Terje R Pedersen Pierre Amarenco Haruo Nakamura John J V McMurray James D Lewsey Daniel I Chasman Paul M Ridker Aldo P Maggioni Luigi Tavazzi Kausik K Ray Sreenivasa Rao Kondapally Seshasai JoAnn E Manson Jackie F Price Peter H Whincup Richard W Morris Debbie A Lawlor George Davey Smith Yoav Ben-Shlomo Pamela J Schreiner Myriam Fornage David S Siscovick Mary Cushman Meena Kumari Nick J Wareham W M Monique Verschuren Susan Redline Sanjay R Patel John C Whittaker Anders Hamsten Joseph A Delaney Caroline Dale Tom R Gaunt Andrew Wong Diana Kuh Rebecca Hardy Sekar Kathiresan Berta A Castillo Pim van der Harst Eric J Brunner Anne Tybjaerg-Hansen Michael G Marmot Ronald M Krauss Michael Tsai Josef Coresh Ronald C Hoogeveen Bruce M Psaty Leslie A Lange Hakon Hakonarson Frank Dudbridge Steve E Humphries Philippa J Talmud Mika Kivimäki Nicholas J Timpson Claudia Langenberg Folkert W Asselbergs Mikhail Voevoda Martin Bobak Hynek Pikhart James G Wilson Alex P Reiner Brendan J Keating Aroon D Hingorani Naveed Sattar

Lancet 2015 Jan 24;385(9965):351-61. Epub 2014 Sep 24.

BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322187PMC
January 2015

Mangravite et al. reply.

Nature 2014 Sep;513(7518):E3

Children's Hospital Research Institute, Oakland, California 94609, USA.

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September 2014

Ancestry and other genetic associations with plasma PCSK9 response to simvastatin.

Pharmacogenet Genomics 2014 Oct;24(10):492-500

aChildren's Hospital Oakland Research Institute, Oakland bLos Angeles Biomedical Research Institute at Harbor-UCLA, Torrance, California, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159722PMC
October 2014

CYP3A4*22 and CYP3A5*3 are associated with increased levels of plasma simvastatin concentrations in the cholesterol and pharmacogenetics study cohort.

Pharmacogenet Genomics 2014 Oct;24(10):486-91

aCenter for Pharmacogenomics, College of Medicine, The Ohio State University,Columbus, Ohio bChildren's Hospital Oakland Research Institute, Oakland, California, USA cDipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.

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October 2014

Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism.

Arterioscler Thromb Vasc Biol 2014 Sep 17;34(9):1917-23. Epub 2014 Jul 17.

From the Children's Hospital Oakland Research Institute, CA (M.W.M., F.B., D.N., E.T., K.S., R.M.K.); Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany (J.S., H.R.); Sage Bionetworks, Seattle, WA (L.M.M.); Section on Lipid Sciences, Department of Pathology, Wake Forest University Health Sciences, Winston-Salem, NC (L.L.R., R.E.T.); and Molecular Medicine Partnership Unit (MMPU), Heidelberg, Germany (C.S., H.R.).

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http://dx.doi.org/10.1161/ATVBAHA.113.302806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141484PMC
September 2014

Overfeeding of polyunsaturated versus saturated fatty acids reduces ectopic fat.

Diabetes 2014 Jul;63(7):2222-4

Children's Hospital Oakland Research Institute, Oakland, CA.

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http://dx.doi.org/10.2337/db14-0493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392897PMC
July 2014

Nonalcoholic steatohepatitis is associated with an atherogenic lipoprotein subfraction profile.

Lipids Health Dis 2014 Jun 21;13:100. Epub 2014 Jun 21.

Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074829PMC
June 2014

All low-density lipoprotein particles are not created equal.

Authors:
Ronald M Krauss

Arterioscler Thromb Vasc Biol 2014 May;34(5):959-61

From the Children's Hospital Oakland Research Institute, Oakland, CA.

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http://dx.doi.org/10.1161/ATVBAHA.114.303458DOI Listing
May 2014

Organophosphorus flame retardants inhibit specific liver carboxylesterases and cause serum hypertriglyceridemia.

ACS Chem Biol 2014 May 10;9(5):1097-103. Epub 2014 Mar 10.

Department of Nutritional Sciences and Toxicology, University of California, Berkeley , 127 Morgan Hall, Berkeley, California 94720, United States.

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http://dx.doi.org/10.1021/cb500014rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027947PMC
May 2014

Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines.

Pharmacogenomics 2014 Feb;15(2):137-46

Bioinformatics Research Center, Department of Statistics, North Carolina State University, Raleigh, NC 27607, USA.

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http://dx.doi.org/10.2217/pgs.13.213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055088PMC
February 2014

Statin-induced changes in gene expression in EBV-transformed and native B-cells.

Hum Mol Genet 2014 Mar 30;23(5):1202-10. Epub 2013 Oct 30.

Children's Hospital Oakland Research Institute, 5700 Martin Luther King Jr. Way, Oakland, CA 94609, USA.

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http://dx.doi.org/10.1093/hmg/ddt512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919007PMC
March 2014

Discovery and refinement of loci associated with lipid levels.

Authors:
Cristen J Willer Ellen M Schmidt Sebanti Sengupta Gina M Peloso Stefan Gustafsson Stavroula Kanoni Andrea Ganna Jin Chen Martin L Buchkovich Samia Mora Jacques S Beckmann Jennifer L Bragg-Gresham Hsing-Yi Chang Ayşe Demirkan Heleen M Den Hertog Ron Do Louise A Donnelly Georg B Ehret Tõnu Esko Mary F Feitosa Teresa Ferreira Krista Fischer Pierre Fontanillas Ross M Fraser Daniel F Freitag Deepti Gurdasani Kauko Heikkilä Elina Hyppönen Aaron Isaacs Anne U Jackson Åsa Johansson Toby Johnson Marika Kaakinen Johannes Kettunen Marcus E Kleber Xiaohui Li Jian'an Luan Leo-Pekka Lyytikäinen Patrik K E Magnusson Massimo Mangino Evelin Mihailov May E Montasser Martina Müller-Nurasyid Ilja M Nolte Jeffrey R O'Connell Cameron D Palmer Markus Perola Ann-Kristin Petersen Serena Sanna Richa Saxena Susan K Service Sonia Shah Dmitry Shungin Carlo Sidore Ci Song Rona J Strawbridge Ida Surakka Toshiko Tanaka Tanya M Teslovich Gudmar Thorleifsson Evita G Van den Herik Benjamin F Voight Kelly A Volcik Lindsay L Waite Andrew Wong Ying Wu Weihua Zhang Devin Absher Gershim Asiki Inês Barroso Latonya F Been Jennifer L Bolton Lori L Bonnycastle Paolo Brambilla Mary S Burnett Giancarlo Cesana Maria Dimitriou Alex S F Doney Angela Döring Paul Elliott Stephen E Epstein Gudmundur Ingi Eyjolfsson Bruna Gigante Mark O Goodarzi Harald Grallert Martha L Gravito Christopher J Groves Göran Hallmans Anna-Liisa Hartikainen Caroline Hayward Dena Hernandez Andrew A Hicks Hilma Holm Yi-Jen Hung Thomas Illig Michelle R Jones Pontiano Kaleebu John J P Kastelein Kay-Tee Khaw Eric Kim Norman Klopp Pirjo Komulainen Meena Kumari Claudia Langenberg Terho Lehtimäki Shih-Yi Lin Jaana Lindström Ruth J F Loos François Mach Wendy L McArdle Christa Meisinger Braxton D Mitchell Gabrielle Müller Ramaiah Nagaraja Narisu Narisu Tuomo V M Nieminen Rebecca N Nsubuga Isleifur Olafsson Ken K Ong Aarno Palotie Theodore Papamarkou Cristina Pomilla Anneli Pouta Daniel J Rader Muredach P Reilly Paul M Ridker Fernando Rivadeneira Igor Rudan Aimo Ruokonen Nilesh Samani Hubert Scharnagl Janet Seeley Kaisa Silander Alena Stančáková Kathleen Stirrups Amy J Swift Laurence Tiret Andre G Uitterlinden L Joost van Pelt Sailaja Vedantam Nicholas Wainwright Cisca Wijmenga Sarah H Wild Gonneke Willemsen Tom Wilsgaard James F Wilson Elizabeth H Young Jing Hua Zhao Linda S Adair Dominique Arveiler Themistocles L Assimes Stefania Bandinelli Franklyn Bennett Murielle Bochud Bernhard O Boehm Dorret I Boomsma Ingrid B Borecki Stefan R Bornstein Pascal Bovet Michel Burnier Harry Campbell Aravinda Chakravarti John C Chambers Yii-Der Ida Chen Francis S Collins Richard S Cooper John Danesh George Dedoussis Ulf de Faire Alan B Feranil Jean Ferrières Luigi Ferrucci Nelson B Freimer Christian Gieger Leif C Groop Vilmundur Gudnason Ulf Gyllensten Anders Hamsten Tamara B Harris Aroon Hingorani Joel N Hirschhorn Albert Hofman G Kees Hovingh Chao Agnes Hsiung Steve E Humphries Steven C Hunt Kristian Hveem Carlos Iribarren Marjo-Riitta Järvelin Antti Jula Mika Kähönen Jaakko Kaprio Antero Kesäniemi Mika Kivimaki Jaspal S Kooner Peter J Koudstaal Ronald M Krauss Diana Kuh Johanna Kuusisto Kirsten O Kyvik Markku Laakso Timo A Lakka Lars Lind Cecilia M Lindgren Nicholas G Martin Winfried März Mark I McCarthy Colin A McKenzie Pierre Meneton Andres Metspalu Leena Moilanen Andrew D Morris Patricia B Munroe Inger Njølstad Nancy L Pedersen Chris Power Peter P Pramstaller Jackie F Price Bruce M Psaty Thomas Quertermous Rainer Rauramaa Danish Saleheen Veikko Salomaa Dharambir K Sanghera Jouko Saramies Peter E H Schwarz Wayne H-H Sheu Alan R Shuldiner Agneta Siegbahn Tim D Spector Kari Stefansson David P Strachan Bamidele O Tayo Elena Tremoli Jaakko Tuomilehto Matti Uusitupa Cornelia M van Duijn Peter Vollenweider Lars Wallentin Nicholas J Wareham John B Whitfield Bruce H R Wolffenbuttel Jose M Ordovas Eric Boerwinkle Colin N A Palmer Unnur Thorsteinsdottir Daniel I Chasman Jerome I Rotter Paul W Franks Samuli Ripatti L Adrienne Cupples Manjinder S Sandhu Stephen S Rich Michael Boehnke Panos Deloukas Sekar Kathiresan Karen L Mohlke Erik Ingelsson Gonçalo R Abecasis

Nat Genet 2013 Nov 6;45(11):1274-1283. Epub 2013 Oct 6.

Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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November 2013

Common variants associated with plasma triglycerides and risk for coronary artery disease.

Authors:
Ron Do Cristen J Willer Ellen M Schmidt Sebanti Sengupta Chi Gao Gina M Peloso Stefan Gustafsson Stavroula Kanoni Andrea Ganna Jin Chen Martin L Buchkovich Samia Mora Jacques S Beckmann Jennifer L Bragg-Gresham Hsing-Yi Chang Ayşe Demirkan Heleen M Den Hertog Louise A Donnelly Georg B Ehret Tõnu Esko Mary F Feitosa Teresa Ferreira Krista Fischer Pierre Fontanillas Ross M Fraser Daniel F Freitag Deepti Gurdasani Kauko Heikkilä Elina Hyppönen Aaron Isaacs Anne U Jackson Asa Johansson Toby Johnson Marika Kaakinen Johannes Kettunen Marcus E Kleber Xiaohui Li Jian'an Luan Leo-Pekka Lyytikäinen Patrik K E Magnusson Massimo Mangino Evelin Mihailov May E Montasser Martina Müller-Nurasyid Ilja M Nolte Jeffrey R O'Connell Cameron D Palmer Markus Perola Ann-Kristin Petersen Serena Sanna Richa Saxena Susan K Service Sonia Shah Dmitry Shungin Carlo Sidore Ci Song Rona J Strawbridge Ida Surakka Toshiko Tanaka Tanya M Teslovich Gudmar Thorleifsson Evita G Van den Herik Benjamin F Voight Kelly A Volcik Lindsay L Waite Andrew Wong Ying Wu Weihua Zhang Devin Absher Gershim Asiki Inês Barroso Latonya F Been Jennifer L Bolton Lori L Bonnycastle Paolo Brambilla Mary S Burnett Giancarlo Cesana Maria Dimitriou Alex S F Doney Angela Döring Paul Elliott Stephen E Epstein Gudmundur Ingi Eyjolfsson Bruna Gigante Mark O Goodarzi Harald Grallert Martha L Gravito Christopher J Groves Göran Hallmans Anna-Liisa Hartikainen Caroline Hayward Dena Hernandez Andrew A Hicks Hilma Holm Yi-Jen Hung Thomas Illig Michelle R Jones Pontiano Kaleebu John J P Kastelein Kay-Tee Khaw Eric Kim Norman Klopp Pirjo Komulainen Meena Kumari Claudia Langenberg Terho Lehtimäki Shih-Yi Lin Jaana Lindström Ruth J F Loos François Mach Wendy L McArdle Christa Meisinger Braxton D Mitchell Gabrielle Müller Ramaiah Nagaraja Narisu Narisu Tuomo V M Nieminen Rebecca N Nsubuga Isleifur Olafsson Ken K Ong Aarno Palotie Theodore Papamarkou Cristina Pomilla Anneli Pouta Daniel J Rader Muredach P Reilly Paul M Ridker Fernando Rivadeneira Igor Rudan Aimo Ruokonen Nilesh Samani Hubert Scharnagl Janet Seeley Kaisa Silander Alena Stančáková Kathleen Stirrups Amy J Swift Laurence Tiret Andre G Uitterlinden L Joost van Pelt Sailaja Vedantam Nicholas Wainwright Cisca Wijmenga Sarah H Wild Gonneke Willemsen Tom Wilsgaard James F Wilson Elizabeth H Young Jing Hua Zhao Linda S Adair Dominique Arveiler Themistocles L Assimes Stefania Bandinelli Franklyn Bennett Murielle Bochud Bernhard O Boehm Dorret I Boomsma Ingrid B Borecki Stefan R Bornstein Pascal Bovet Michel Burnier Harry Campbell Aravinda Chakravarti John C Chambers Yii-Der Ida Chen Francis S Collins Richard S Cooper John Danesh George Dedoussis Ulf de Faire Alan B Feranil Jean Ferrières Luigi Ferrucci Nelson B Freimer Christian Gieger Leif C Groop Vilmundur Gudnason Ulf Gyllensten Anders Hamsten Tamara B Harris Aroon Hingorani Joel N Hirschhorn Albert Hofman G Kees Hovingh Chao Agnes Hsiung Steve E Humphries Steven C Hunt Kristian Hveem Carlos Iribarren Marjo-Riitta Järvelin Antti Jula Mika Kähönen Jaakko Kaprio Antero Kesäniemi Mika Kivimaki Jaspal S Kooner Peter J Koudstaal Ronald M Krauss Diana Kuh Johanna Kuusisto Kirsten O Kyvik Markku Laakso Timo A Lakka Lars Lind Cecilia M Lindgren Nicholas G Martin Winfried März Mark I McCarthy Colin A McKenzie Pierre Meneton Andres Metspalu Leena Moilanen Andrew D Morris Patricia B Munroe Inger Njølstad Nancy L Pedersen Chris Power Peter P Pramstaller Jackie F Price Bruce M Psaty Thomas Quertermous Rainer Rauramaa Danish Saleheen Veikko Salomaa Dharambir K Sanghera Jouko Saramies Peter E H Schwarz Wayne H-H Sheu Alan R Shuldiner Agneta Siegbahn Tim D Spector Kari Stefansson David P Strachan Bamidele O Tayo Elena Tremoli Jaakko Tuomilehto Matti Uusitupa Cornelia M van Duijn Peter Vollenweider Lars Wallentin Nicholas J Wareham John B Whitfield Bruce H R Wolffenbuttel David Altshuler Jose M Ordovas Eric Boerwinkle Colin N A Palmer Unnur Thorsteinsdottir Daniel I Chasman Jerome I Rotter Paul W Franks Samuli Ripatti L Adrienne Cupples Manjinder S Sandhu Stephen S Rich Michael Boehnke Panos Deloukas Karen L Mohlke Erik Ingelsson Goncalo R Abecasis Mark J Daly Benjamin M Neale Sekar Kathiresan

Nat Genet 2013 Nov 6;45(11):1345-52. Epub 2013 Oct 6.

1] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. [4] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.2795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904346PMC
November 2013

High-density lipoproteins: a consensus statement from the National Lipid Association.

J Clin Lipidol 2013 Sep-Oct;7(5):484-525. Epub 2013 Aug 11.

CGH Medical Center, Sterling, IL 61081, USA; University of Illinois School of Medicine, Peoria, IL, USA; Michigan State University College of Osteopathic Medicine, East Lansing, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2013.08.001DOI Listing
October 2014