Ronald M Evans

Ronald M Evans

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Ronald M Evans

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E47 modulates hepatic glucocorticoid action.

Nat Commun 2019 Jan 18;10(1):306. Epub 2019 Jan 18.

Molecular Endocrinology, Helmholtz Diabetes Center (HMGU) and German Center for Diabetes Research (DZD), IDO, Ingolstädter Landstr. 1, 85764, Neuherberg, Munich, Germany.

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http://dx.doi.org/10.1038/s41467-018-08196-5DOI Listing
January 2019

Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity.

Cell Rep 2018 Dec;25(12):3283-3298.e6

Division of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183185
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http://dx.doi.org/10.1016/j.celrep.2018.11.074DOI Listing
December 2018

Author Correction: Inflammation-induced IgA cells dismantle anti-liver cancer immunity.

Nature 2018 09;561(7721):E1

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, California, 92093, USA.

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http://dx.doi.org/10.1038/s41586-018-0304-yDOI Listing
September 2018

Ligand-Dependent Corepressor (LCoR) Is a Rexinoid-Inhibited Peroxisome Proliferator-Activated Receptor γ-Retinoid X Receptor α Coactivator.

Mol Cell Biol 2018 May 16;38(9). Epub 2018 Apr 16.

Magee-Womens Research Institute, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

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http://dx.doi.org/10.1128/MCB.00107-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902596PMC
May 2018

Rational application of macrophage-specific LXR agonists avoids the pitfalls of SREBP-induced lipogenesis.

Proc Natl Acad Sci U S A 2018 05 30;115(20):5051-5053. Epub 2018 Apr 30.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037;

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http://dx.doi.org/10.1073/pnas.1805128115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960336PMC
May 2018

Vitamin D Switches BAF Complexes to Protect β Cells.

Cell 2018 May 10;173(5):1135-1149.e15. Epub 2018 May 10.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987229PMC
May 2018

Visible light reduces C. elegans longevity.

Nat Commun 2018 03 2;9(1):927. Epub 2018 Mar 2.

The Howard Hughes Medical Institute, Molecular and Cell Biology Department, Li Ka Shing Center, University of California Berkeley, Berkeley, CA, 94720, USA.

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http://dx.doi.org/10.1038/s41467-018-02934-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834526PMC
March 2018

ERRγ Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1α/β-Deficient Muscle.

Cell Rep 2018 Mar;22(10):2521-2529

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.02.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860878PMC
March 2018

ERRγ Preserves Brown Fat Innate Thermogenic Activity.

Cell Rep 2018 Mar;22(11):2849-2859

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.02.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884669PMC
March 2018

Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and Cancer.

Cold Spring Harb Symp Quant Biol 2015 22;80:249-55. Epub 2016 Jan 22.

Gene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037 Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, California 92037.

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http://dx.doi.org/10.1101/sqb.2015.80.027185DOI Listing
January 2018

Metabolic control of regulatory T cell (Treg) survival and function by Lkb1.

Proc Natl Acad Sci U S A 2017 11 6;114(47):12542-12547. Epub 2017 Nov 6.

Gene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037;

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http://dx.doi.org/10.1073/pnas.1715363114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703326PMC
November 2017

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity.

Nature 2017 11 8;551(7680):340-345. Epub 2017 Nov 8.

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego (UCSD), 9500 Gilman Drive, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1038/nature24302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884449PMC
November 2017

FGF1 - a new weapon to control type 2 diabetes mellitus.

Nat Rev Endocrinol 2017 Oct 30;13(10):599-609. Epub 2017 Jun 30.

Gene Expression Laboratory, Salk Institute for Biological Studies.

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http://dx.doi.org/10.1038/nrendo.2017.78DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839646PMC
October 2017

NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection.

Nat Commun 2017 10 16;8(1):959. Epub 2017 Oct 16.

CAS Key Laboratory of Molecular Virology & Immunology, Unit of Immune Regulation, Institut Pasteur of Shanghai, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.

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http://dx.doi.org/10.1038/s41467-017-00931-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643384PMC
October 2017

30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Short reflections on the discovery of the mineralocorticoid receptor.

Authors:
Ronald M Evans

J Endocrinol 2017 07;234(1):E1-E2

Howard Hughes Medical InstituteSalk Institute for Biological Studies, La Jolla, California, USA

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http://dx.doi.org/10.1530/JOE-17-0287DOI Listing
July 2017

Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes.

Cell Metab 2017 Jul;26(1):157-170.e7

Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA; Departments of Medicine and Pharmacology, University of California, San Diego School of Medicine, La Jolla, CA 92093, USA; Institute of Diabetes and Metabolic Health, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0757, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663294PMC
July 2017

Farnesoid X Receptor an Emerging Target to Combat Obesity.

Dig Dis 2017 1;35(3):185-190. Epub 2017 Mar 1.

Gene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, Calif., USA.

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http://dx.doi.org/10.1159/000450909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417073PMC
May 2017

PPARδ Promotes Running Endurance by Preserving Glucose.

Cell Metab 2017 May;25(5):1186-1193.e4

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492977PMC
May 2017

Re-engineering the Pancreas Tumor Microenvironment: A "Regenerative Program" Hacked.

Clin Cancer Res 2017 Apr;23(7):1647-1655

Gene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-3275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381729PMC
April 2017

Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia.

Sci Rep 2017 04 12;7(1):846. Epub 2017 Apr 12.

Section of Molecular Metabolism and Nutrition, Department of Pediatrics, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-017-00889-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429805PMC
April 2017

Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ.

Proc Natl Acad Sci U S A 2017 03 20;114(13):E2563-E2570. Epub 2017 Mar 20.

Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037;

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http://dx.doi.org/10.1073/pnas.1621513114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380080PMC
March 2017

Exercise Mimetics: Impact on Health and Performance.

Cell Metab 2017 02 23;25(2):242-247. Epub 2016 Nov 23.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.10.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555683PMC
February 2017

Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.

Proc Natl Acad Sci U S A 2017 02 6;114(8):E1432-E1440. Epub 2017 Feb 6.

Laboratory of Environmental Toxicology, Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093.

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http://dx.doi.org/10.1073/pnas.1700232114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338369PMC
February 2017

Liver Cancer Checks in When Bile Acid Clocks Out.

Cancer Cell 2016 Dec;30(6):827-828

Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439430PMC
December 2016

Reply to "PPAR-γ regulates pharmacological but not physiological or pathological osteoclast formation".

Nat Med 2016 11;22(11):1205

Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1038/nm.4207DOI Listing
November 2016

Barx2 and Pax7 Regulate Axin2 Expression in Myoblasts by Interaction with β-Catenin and Chromatin Remodelling.

Stem Cells 2016 08 6;34(8):2169-82. Epub 2016 Jun 6.

Department of Clinical Pharmacology, Flinders University, Bedford Park, South Australia, Australia.

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http://dx.doi.org/10.1002/stem.2396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019118PMC
August 2016

Nuclear receptors and AMPK: can exercise mimetics cure diabetes?

J Mol Endocrinol 2016 07 22;57(1):R49-58. Epub 2016 Apr 22.

Gene Expression LaboratorySalk Institute, La Jolla, California, USA Howard Hughes Medical InstituteSalk Institute, La Jolla, California, USA

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http://dx.doi.org/10.1530/JME-16-0073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929025PMC
July 2016

Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation.

Cell 2016 Jun 26;165(7):1644-1657. Epub 2016 May 26.

Gene Expression Laboratory, Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912445PMC
June 2016

ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cells.

Cell Metab 2016 Apr;23(4):622-34

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832237PMC
April 2016

PPARδ preserves a high resistance to fatigue in the mouse medial gastrocnemius after spinal cord transection.

Muscle Nerve 2016 Feb 26;53(2):287-96. Epub 2015 Nov 26.

Department of Integrative Biology and Physiology, University of California, Los Angeles, 610 Charles E. Young Drive East, Los Angeles, California, 90095-7239, USA.

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http://dx.doi.org/10.1002/mus.24723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670275PMC
February 2016

Fibroblast Growth Factor Signaling in Metabolic Regulation.

Front Endocrinol (Lausanne) 2015 19;6:193. Epub 2016 Jan 19.

Gene Expression Laboratory, Salk Institute for Biological Studies , La Jolla, CA , USA.

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http://dx.doi.org/10.3389/fendo.2015.00193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718082PMC
February 2016

Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease.

Proc Natl Acad Sci U S A 2016 Feb 8;113(8):2288-93. Epub 2016 Feb 8.

Center for Liver, Digestive and Metabolic Diseases, Department of Pediatrics, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1525093113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776526PMC
February 2016

Depletion of fat-resident Treg cells prevents age-associated insulin resistance.

Nature 2015 Dec 18;528(7580):137-41. Epub 2015 Nov 18.

Immunobiology and Microbial Pathogenesis Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nature16151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670283PMC
December 2015

BRD4 is a novel therapeutic target for liver fibrosis.

Proc Natl Acad Sci U S A 2015 Dec 7;112(51):15713-8. Epub 2015 Dec 7.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037

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http://dx.doi.org/10.1073/pnas.1522163112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697417PMC
December 2015

Phosphorylation of the nuclear receptor corepressor 1 by protein kinase B switches its corepressor targets in the liver in mice.

Hepatology 2015 Nov 22;62(5):1606-18. Epub 2015 Jul 22.

Laboratory of Integrative and Systems Physiology, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1002/hep.27907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618256PMC
November 2015

Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer.

Mol Cancer Res 2015 Nov 29;13(11):1509-19. Epub 2015 Jul 29.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California. Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, California.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644680PMC
November 2015

Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling.

Science 2015 Oct;350(6260):558-63

Nomis Center for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1126/science.aac6468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732872PMC
October 2015

Imaging Fibrosis and Separating Collagens using Second Harmonic Generation and Phasor Approach to Fluorescence Lifetime Imaging.

Sci Rep 2015 Aug 21;5:13378. Epub 2015 Aug 21.

Laboratory for Fluorescence Dynamics, Department of Biomedical Engineering, University of California Irvine, California.

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http://dx.doi.org/10.1038/srep13378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543938PMC
August 2015

High-fat diet and FGF21 cooperatively promote aerobic thermogenesis in mtDNA mutator mice.

Proc Natl Acad Sci U S A 2015 Jul 29;112(28):8714-9. Epub 2015 Jun 29.

Gene Expression Laboratory, Salk Institute, La Jolla, CA 92037; Howard Hughes Medical Institute, Salk Institute, La Jolla, CA 92037

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http://dx.doi.org/10.1073/pnas.1509930112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507233PMC
July 2015

Nuclear Receptor Signaling: a home for nuclear receptor and coregulator signaling research.

Nucl Recept Signal 2014 15;12:e006. Epub 2014 Dec 15.

Nuclear Receptor Signaling Atlas (NJM, RME, BWO) and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030 (NJM, BWO), and Gene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037 (RME).

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http://journals.sagepub.com/doi/10.1621/nrs.12006
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http://dx.doi.org/10.1621/nrs.12006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303009PMC
June 2015

ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency.

Cell Stem Cell 2015 May 9;16(5):547-55. Epub 2015 Apr 9.

Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427539PMC
May 2015

Turning up the heat on membrane fluidity.

Cell 2015 May;161(5):962-963

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.04.046DOI Listing
May 2015

Estrogen-related receptor α (ERRα) and ERRγ are essential coordinators of cardiac metabolism and function.

Mol Cell Biol 2015 Apr 26;35(7):1281-98. Epub 2015 Jan 26.

Center for Mitochondrial and Epigenomic Medicine, Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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http://dx.doi.org/10.1128/MCB.01156-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355525PMC
April 2015

Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism.

Cell Metab 2015 Apr;21(4):628-36

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393848PMC
April 2015

Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs.

Proc Natl Acad Sci U S A 2015 Jan 6;112(3):E297-302. Epub 2015 Jan 6.

Gene Expression Laboratory, Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037

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http://dx.doi.org/10.1073/pnas.1424028112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311831PMC
January 2015

The commonly used antimicrobial additive triclosan is a liver tumor promoter.

Proc Natl Acad Sci U S A 2014 Dec 17;111(48):17200-5. Epub 2014 Nov 17.

Laboratory of Environmental Toxicology, Departments of Chemistry & Biochemistry and Pharmacology, and

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http://www.pnas.org/lookup/doi/10.1073/pnas.1419119111
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http://dx.doi.org/10.1073/pnas.1419119111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260592PMC
December 2014

Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.

Nature 2014 Sep 16;513(7518):436-9. Epub 2014 Jul 16.

1] Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA [2] Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nature13540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184286PMC
September 2014

Methylome, transcriptome, and PPAR(γ) cistrome analyses reveal two epigenetic transitions in fat cells.

Epigenetics 2014 Sep 10;9(9):1195-206. Epub 2014 Jul 10.

Research Center for Stem Cell Engineering; National Institute of Advanced Industrial Science and Technology (AIST); Tsukuba, Japan.

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http://dx.doi.org/10.4161/epi.29856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169011PMC
September 2014

The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages.

Genes Dev 2014 Jul;28(14):1562-77

Department of Biochemistry and Molecular Biology, University of Debrecen, Debrecen H-4032, Hungary; MTA-DE Lendület Immunogenomics Research Group, University of Debrecen, Debrecen H-4032, Hungary.

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http://dx.doi.org/10.1101/gad.242685.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102764PMC
July 2014

Nuclear receptors and metabolism: from feast to famine.

Diabetologia 2014 May 12;57(5):860-7. Epub 2014 Mar 12.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.

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http://link.springer.com/10.1007/s00125-014-3209-9
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http://dx.doi.org/10.1007/s00125-014-3209-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980036PMC
May 2014

Nuclear receptors rock around the clock.

EMBO Rep 2014 May 15;15(5):518-28. Epub 2014 Apr 15.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.

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http://dx.doi.org/10.1002/embr.201338271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210094PMC
May 2014

Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene.

Am J Physiol Heart Circ Physiol 2014 Apr 31;306(7):H1001-10. Epub 2014 Jan 31.

Department of Anesthesiology and Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota; and.

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http://www.physiology.org/doi/10.1152/ajpheart.00761.2013
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http://dx.doi.org/10.1152/ajpheart.00761.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962632PMC
April 2014

Metabolism: Tick, tock, a high-fat clock.

Nat Rev Endocrinol 2014 Apr 4;10(4):191-2. Epub 2014 Mar 4.

Howard Hughes Medical Institute, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1038/nrendo.2014.23DOI Listing
April 2014

Nuclear Receptors, RXR, and the Big Bang.

Cell 2014 Mar;157(1):255-66

Howard Hughes Medical Institute; The Department of Pharmacology, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029515PMC
March 2014

Journal of Molecular Endocrinology 25th anniversary special issue.

Authors:
Ronald M Evans

J Mol Endocrinol 2013 Dec 26;51(3):E1-3. Epub 2013 Nov 26.

Investigator, Howard Hughes Medical Institute and Professor, Salk Institute for Biological Studies, La Jolla, CA, USA.

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December 2013

Road to exercise mimetics: targeting nuclear receptors in skeletal muscle.

J Mol Endocrinol 2013 Dec 26;51(3):T87-T100. Epub 2013 Nov 26.

Gene Expression Laboratory Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, California 92037, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936671PMC
December 2013

Hepatic actions of vitamin D receptor ligands: a sunshine option for chronic liver disease?

Expert Rev Clin Pharmacol 2013 Nov;6(6):597-9

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California, USA.

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http://dx.doi.org/10.1586/17512433.2013.841078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160153PMC
November 2013

Rescue of a primary myelofibrosis model by retinoid-antagonist therapy.

Proc Natl Acad Sci U S A 2013 Nov 4;110(47):18820-5. Epub 2013 Nov 4.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839709PMC
November 2013

Microbiology: Wealth management in the gut.

Nature 2013 Aug;500(7464):538-9

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August 2013

PPARγ signaling and metabolism: the good, the bad and the future.

Nat Med 2013 May 7;19(5):557-66. Epub 2013 May 7.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nm.3159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870016PMC
May 2013

Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease.

Proc Natl Acad Sci U S A 2013 May 7;110(21):8555-60. Epub 2013 May 7.

Department of Medicine and Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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May 2013

Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice.

J Lipid Res 2013 Mar 3;54(3):806-15. Epub 2013 Jan 3.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.

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March 2013

SRF'ing around the clock.

Cell 2013 Jan;152(3):381-2

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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January 2013

Targeting the pregnane X receptor in liver injury.

Expert Opin Ther Targets 2012 Nov 23;16(11):1075-83. Epub 2012 Aug 23.

The Salk Institute for Biological Studies, Gene Expression Laboratory, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319648PMC
November 2012