Ronald J Quinn

Ronald J Quinn

UNVERIFIED PROFILE

Are you Ronald J Quinn?   Register this Author

Register author
Ronald J Quinn

Ronald J Quinn

Publications by authors named "Ronald J Quinn"

Are you Ronald J Quinn?   Register this Author

100Publications

2162Reads

46Profile Views

Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein.

Acta Pharmacol Sin 2020 Apr 4;41(4):483-498. Epub 2019 Oct 4.

Griffith Institute for Drug Discovery, Griffith University, Brisbane Innovation Park, Don Young Road, Nathan, QLD, 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41401-019-0304-yDOI Listing
April 2020

A Phenotarget Approach for Identifying an Alkaloid Interacting with the Tuberculosis Protein Rv1466.

Mar Drugs 2020 Mar 5;18(3). Epub 2020 Mar 5.

Griffith Institute for Drug Discovery, Griffith University, Brisbane, Queensland 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/md18030149DOI Listing
March 2020

Genome-based mining of new antimicrobial meroterpenoids from the phytopathogenic fungus Bipolaris sorokiniana strain 11134.

Appl Microbiol Biotechnol 2020 Mar 26. Epub 2020 Mar 26.

Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD, 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-020-10522-1DOI Listing
March 2020

Fragment-based screening with natural products for novel anti-parasitic disease drug discovery.

Expert Opin Drug Discov 2019 12 12;14(12):1283-1295. Epub 2019 Sep 12.

Griffith Institute for Drug Discovery, Griffith University , Brisbane , Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/17460441.2019.1653849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816479PMC
December 2019

Is it time for artificial intelligence to predict the function of natural products based on 2D-structure.

Medchemcomm 2019 Oct 6;10(10):1667-1677. Epub 2019 Jun 6.

Griffith Institute for Drug Discovery , Griffith University , Brisbane , Qld 4111 , Australia . Email: ; Tel: +61 7 3735 6006.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c9md00128jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836574PMC
October 2019

Comprehensive TCM molecular networking based on MS/MS in silico spectra with integration of virtual screening and affinity MS screening for discovering functional ligands from natural herbs.

Anal Bioanal Chem 2019 Sep 24;411(22):5785-5797. Epub 2019 Jun 24.

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin, 300353, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00216-019-01962-4DOI Listing
September 2019

Traditional Chinese medicine extraction method by ethanol delivers drug-like molecules.

Chin J Nat Med 2019 Sep;17(9):713-720

Griffith Institute of Drug Discovery (GRIDD), Griffith University, Queensland 4111, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1875-5364(19)30086-XDOI Listing
September 2019

Genome- and MS-based mining of antibacterial chlorinated chromones and xanthones from the phytopathogenic fungus Bipolaris sorokiniana strain 11134.

Appl Microbiol Biotechnol 2019 Jul 19;103(13):5167-5181. Epub 2019 Apr 19.

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-019-09821-zDOI Listing
July 2019

Potential of marine natural products against drug-resistant bacterial infections.

Lancet Infect Dis 2019 Jul 25;19(7):e237-e245. Epub 2019 Apr 25.

Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1473-3099(18)30711-4DOI Listing
July 2019

Development of an HPLC-based guanosine monophosphate kinase assay and application to Plasmodium vivax guanylate kinase.

Anal Biochem 2019 06 31;575:63-69. Epub 2019 Mar 31.

Griffith Institute for Drug Discovery, Griffith University, Brisbane, Queensland, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ab.2019.03.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494078PMC
June 2019

Identification of a New α-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening.

ACS Chem Neurosci 2019 06 4;10(6):2683-2691. Epub 2019 Jun 4.

Griffith Institute for Drug Discovery , Griffith University , Don Young Road , Nathan , QLD 4111 , Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acschemneuro.9b00092DOI Listing
June 2019

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

Nat Prod Rep 2019 01 13;36(1):35-107. Epub 2018 Jul 13.

Center for Natural Product Technologies (CENAPT), Program for Collaborative Research in the Pharmaceutical Sciences (PCRPS), Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 S. Wood St., Chicago, IL 60612, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c7np00064bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350634PMC
January 2019

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

Nat Prod Rep 2019 01 23;36(1):248-249. Epub 2018 Nov 23.

Center for Natural Product Technologies (CENAPT), Program for Collaborative Research in the Pharmaceutical Sciences (PCRPS), Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 S. Wood St., Chicago, IL 60612, USA.

View Article

Download full-text PDF

Source
http://xlink.rsc.org/?DOI=C8NP90041H
Publisher Site
http://dx.doi.org/10.1039/c8np90041hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474672PMC
January 2019

5,6,7,3',4',5'-Hexamethoxyflavone from the Australian plant Eremophila debilis (Myoporaceae).

Fitoterapia 2018 Apr 1;126:90-92. Epub 2017 Aug 1.

Griffith Institute for Drug Discovery, Griffith University, Brisbane, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fitote.2017.07.014DOI Listing
April 2018

Structural Searching of Biosynthetic Enzymes to Predict Protein Targets of Natural Products.

Planta Med 2018 Mar 3;84(5):304-310. Epub 2017 Nov 3.

Laboratory of Therapeutic Innovation, Medalis Drug Discovery Center, University of Strasbourg, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0043-121992DOI Listing
March 2018

Identification of natural products as novel ligands for the human 5-HT receptor.

Biophys Rep 2018 9;4(1):50-61. Epub 2018 Mar 9.

1National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101 China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s41048-018-0047-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860131PMC
March 2018

Harnessing the Properties of Natural Products.

Annu Rev Pharmacol Toxicol 2018 01 2;58:451-470. Epub 2017 Oct 2.

Griffith Institute for Drug Discovery, Griffith University, Brisbane, Queensland 4111, Australia; email: ,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-pharmtox-010716-105029DOI Listing
January 2018

A systems approach using OSMAC, Log P and NMR fingerprinting: An approach to novelty.

Synth Syst Biotechnol 2017 Dec 21;2(4):276-286. Epub 2017 Oct 21.

Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD, 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.synbio.2017.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851912PMC
December 2017

Achyrodimer F, a tyrosyl-DNA phosphodiesterase I inhibitor from an Australian fungus of the family Cortinariaceae.

Bioorg Med Chem Lett 2017 09 24;27(17):4007-4010. Epub 2017 Jul 24.

Griffith Institute for Drug Discovery, Griffith University, Brisbane QLD 4111, Australia. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0960894X173076
Publisher Site
http://dx.doi.org/10.1016/j.bmcl.2017.07.062DOI Listing
September 2017

Dereplication of cytotoxic compounds from different parts of Sophora pachycarpa using an integrated method of HPLC, LC-MS and H-NMR techniques.

Nat Prod Res 2017 Jun 3;31(11):1270-1276. Epub 2016 Oct 3.

a School of Pharmacy, Biotechnology Research Center , Mashhad University of Medical Sciences , Mashhad , Iran.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14786419.2016.1239095DOI Listing
June 2017

Actinomycete Metabolome Induction/Suppression with N-Acetylglucosamine.

J Nat Prod 2017 04 29;80(4):828-836. Epub 2017 Mar 29.

Eskitis Institute for Drug Discovery, Griffith University , Brisbane, QLD 4111 Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.6b00673DOI Listing
April 2017

Potential of marine natural products against drug-resistant fungal, viral, and parasitic infections.

Lancet Infect Dis 2017 Feb 13;17(2):e30-e41. Epub 2016 Dec 13.

Department of Botany II, Julius-von-Sachs-Institute for Biological Sciences, University of Würzburg, Würzburg, Germany; GEOMAR Helmholtz Centre for Ocean Research, RD3 Marine Microbiology, Kiel, Germany; Christian-Albrechts University of Kiel, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1473-3099(16)30323-1DOI Listing
February 2017

Cytotoxic ethnic Yao medicine Baizuan, leaves of Schisandra viridis A. C. Smith.

J Ethnopharmacol 2016 Dec 13;194:146-152. Epub 2016 Sep 13.

Eskitis Institute, Griffith University, 170 Kessels Road, Brisbane QLD 4111, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jep.2016.09.016DOI Listing
December 2016

Merosesquiterpene Congeners from the Australian Sponge Hyrtios digitatus as Potential Drug Leads for Atherosclerosis Disease.

Mar Drugs 2016 Dec 27;15(1). Epub 2016 Dec 27.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/md15010006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295226PMC
December 2016

Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity.

Appl Microbiol Biotechnol 2016 Oct 20;100(19):8349-57. Epub 2016 May 20.

Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-016-7488-6DOI Listing
October 2016

Comparing atom-based with residue-based descriptors in predicting binding site similarity: do backbone atoms matter?

Future Med Chem 2016 Oct 15;8(15):1871-1885. Epub 2016 Sep 15.

UMR 7200 CNRS/Université de Strasbourg, MEDALIS Drug Discovery Center, 74 Route du Rhin, 67401, Illkirch, France.

View Article

Download full-text PDF

Source
http://www.future-science.com/doi/10.4155/fmc-2016-0077
Publisher Site
http://dx.doi.org/10.4155/fmc-2016-0077DOI Listing
October 2016

Optimization of Electrospray Ionization by Statistical Design of Experiments and Response Surface Methodology: Protein-Ligand Equilibrium Dissociation Constant Determinations.

J Am Soc Mass Spectrom 2016 09 25;27(9):1520-30. Epub 2016 May 25.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Queensland, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13361-016-1417-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972871PMC
September 2016

Linckosides enhance proliferation and induce morphological changes in human olfactory ensheathing cells.

Mol Cell Neurosci 2016 09 22;75:1-13. Epub 2016 Jun 22.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mcn.2016.06.005DOI Listing
September 2016

Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation.

Synth Syst Biotechnol 2016 Sep 1;1(3):187-194. Epub 2016 Jul 1.

Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.synbio.2016.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640788PMC
September 2016

A model to predict anti-tuberculosis activity: value proposition for marine microorganisms.

J Antibiot (Tokyo) 2016 Aug 13;69(8):594-9. Epub 2016 Jul 13.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, QLD, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ja.2016.87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399163PMC
August 2016

A Grand Challenge. 2. Phenotypic Profiling of a Natural Product Library on Parkinson's Patient-Derived Cells.

J Nat Prod 2016 08 22;79(8):1982-9. Epub 2016 Jul 22.

Eskitis Institute for Drug Discovery, Griffith University , Brisbane, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.6b00258DOI Listing
August 2016

Tyrosinase inhibitory properties of phenylpropanoid glycosides and flavonoids from L. var. .

Iran J Basic Med Sci 2016 Aug;19(8):804-811

Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048114PMC
August 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Native Mass Spectrometry in Fragment-Based Drug Discovery.

Molecules 2016 Jul 28;21(8). Epub 2016 Jul 28.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane 4111, Queensland, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules21080984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274484PMC
July 2016

Lignans from the Australian Endemic Plant Austrobaileya scandens.

J Nat Prod 2016 06 23;79(6):1514-23. Epub 2016 May 23.

Eskitis Institute for Drug Discovery, Griffith University , Brisbane, Queensland 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.5b00988DOI Listing
June 2016

The Small Molecule R-(-)-β-O-Methylsynephrine Binds to Nucleoporin 153 kDa and Inhibits Angiogenesis.

Int J Biol Sci 2015 16;11(9):1088-99. Epub 2015 Jul 16.

1. Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea ; 6. Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, Republic of Korea.

View Article

Download full-text PDF

Source
http://www.ijbs.com/v11p1088.htm
Publisher Site
http://dx.doi.org/10.7150/ijbs.10603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515819PMC
May 2016

Capturing nature's diversity.

PLoS One 2015 22;10(4):e0120942. Epub 2015 Apr 22.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Queensland, Australia.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120942PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406718PMC
April 2016

Unique Polybrominated Hydrocarbons from the Australian Endemic Red Alga Ptilonia australasica.

J Nat Prod 2016 Mar 23;79(3):570-7. Epub 2016 Feb 23.

Eskitis Institute for Drug Discovery, Griffith University , Brisbane, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.5b00989DOI Listing
March 2016

Lipoxygenase inhibitors from the latex of Calotropis Procera.

Arch Pharm Res 2016 Mar 9. Epub 2016 Mar 9.

Department of Botany and Microbiology, Faculty of Science, Assiut University, Assiut, Egypt.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12272-016-0725-9DOI Listing
March 2016

Bioaffinity Mass Spectrometry Screening.

J Biomol Screen 2016 Feb;21(2):194-200

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Australia

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1087057115622605DOI Listing
February 2016

A Grand Challenge: Unbiased Phenotypic Function of Metabolites from Jaspis splendens against Parkinson's Disease.

J Nat Prod 2016 Feb 17;79(2):353-61. Epub 2016 Feb 17.

Eskitis Institute for Drug Discovery, Griffith University , Brisbane, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.5b00987DOI Listing
February 2016

Dereplication of antioxidant compounds in Bene (Pistacia atlantica subsp. mutica) hull using a multiplex approach of HPLC-DAD, LC-MS and (1)H NMR techniques.

J Pharm Biomed Anal 2016 Jan 8;117:352-62. Epub 2015 Sep 8.

Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpba.2015.09.005DOI Listing
January 2016

TCM, brain function and drug space.

Nat Prod Rep 2016 Jan;33(1):6-25

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia. and Eskitis-SIMM Joint Laboratory for Drug Discovery, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c5np00049aDOI Listing
January 2016

Elicitation of secondary metabolism in actinomycetes.

Biotechnol Adv 2015 Nov 15;33(6 Pt 1):798-811. Epub 2015 Jun 15.

Department of Botany II, Julius-von-Sachs-Institute for Biological Sciences, University of Würzburg, Julius-von-Sachs-Platz 3, 97082 Würzburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biotechadv.2015.06.003DOI Listing
November 2015

Cytotoxic cardenolides from the latex of Calotropis procera.

Bioorg Med Chem Lett 2015 Oct 21;25(20):4615-20. Epub 2015 Aug 21.

Department of Botany and Microbiology, Faculty of Science, Assiut University, Assiut, Egypt. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2015.08.044DOI Listing
October 2015

Tyrosyl-DNA Phosphodiesterase I Inhibitors from the Australian Plant Macropteranthes leichhardtii.

J Nat Prod 2015 Jul 7;78(7):1756-60. Epub 2015 Jul 7.

†Eskitis Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.5b00211DOI Listing
July 2015

Isolation and Total Synthesis of Stolonines A-C, Unique Taurine Amides from the Australian Marine Tunicate Cnemidocarpa stolonifera.

Mar Drugs 2015 Jul 22;13(7):4556-75. Epub 2015 Jul 22.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Queensland 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/md13074556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515633PMC
July 2015

LAT Transport Inhibitors from Pittosporum venulosum Identified by NMR Fingerprint Analysis.

J Nat Prod 2015 Jun 18;78(6):1215-20. Epub 2015 May 18.

†Eskitis Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/np500968tDOI Listing
June 2015

Similarity between Flavonoid Biosynthetic Enzymes and Flavonoid Protein Targets Captured by Three-Dimensional Computing Approach.

Planta Med 2015 Apr 26;81(6):467-73. Epub 2015 Feb 26.

Laboratory of Therapeutic Innovation, Medalis Drug Discovery Center, Université de Strasbourg, Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0035-1545697DOI Listing
April 2015

In silico Driven Pharmacognosy: Forth, Back and Reverse.

Planta Med 2015 Apr 4;81(6):427-8. Epub 2015 May 4.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0035-1545940DOI Listing
April 2015

Eco-taxonomic insights into actinomycete symbionts of termites for discovery of novel bioactive compounds.

Adv Biochem Eng Biotechnol 2015 ;147:111-35

Faculty of Science, Health, Education and Engineering, University of the Sunshine Coast, Maroochydore DC, QLD, 4558, Australia,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/10_2014_270DOI Listing
March 2015

The re-emergence of natural products for drug discovery in the genomics era.

Nat Rev Drug Discov 2015 Feb 23;14(2):111-29. Epub 2015 Jan 23.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Queensland 4111, Australia.

View Article

Download full-text PDF

Source
http://www.nature.com/nrd/journal/v14/n2/pdf/nrd4510.pdf?WT.
Web Search
http://dx.doi.org/10.1038/nrd4510DOI Listing
February 2015

Total synthesis of clavatadine A.

J Nat Prod 2015 Jan 17;78(1):120-4. Epub 2014 Dec 17.

Department of Chemistry, Central Washington University , 400 East University Way, Ellensburg, Washington 98926-7539, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/np500772uDOI Listing
January 2015

Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii.

J Asian Nat Prod Res 2014 Dec 31;16(12):1148-52. Epub 2014 Oct 31.

a Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences , Mashhad , Iran.

View Article

Download full-text PDF

Source
http://www.tandfonline.com/doi/abs/10.1080/10286020.2014.969
Publisher Site
http://dx.doi.org/10.1080/10286020.2014.969717DOI Listing
December 2014

Two new antioxidant actinosporin analogues from the calcium alginate beads culture of sponge-associated Actinokineospora sp. strain EG49.

Bioorg Med Chem Lett 2014 Nov 6;24(21):5089-92. Epub 2014 Sep 6.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2014.08.068DOI Listing
November 2014

Chemical constituents of kino extract from Corymbia torelliana.

Molecules 2014 Nov 4;19(11):17862-71. Epub 2014 Nov 4.

Genecology Research Centre, Faculty of Science, Health, Education and Engineering, University of the Sunshine Coast, Maroochydore DC, Queensland 4558, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules191117862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270844PMC
November 2014

The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer.

Oncotarget 2014 Oct;5(19):9362-81

Australian Prostate Cancer Research Centre - Queensland, Institute of Health and Biomedical Innovation, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Brisbane,Australia. Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Vancouver, Canada.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253440PMC
http://dx.doi.org/10.18632/oncotarget.2433DOI Listing
October 2014

Predicting natural product value, an exploration of anti-TB drug space.

Nat Prod Rep 2014 Aug;31(8):990-8

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Queensland, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c4np00021hDOI Listing
August 2014

ApoE secretion modulating bromotyrosine derivative from the Australian marine sponge Callyspongia sp.

Bioorg Med Chem Lett 2014 Aug 2;24(15):3537-40. Epub 2014 Jun 2.

Eskitis Institute, Griffith University, Brisbane, QLD 4111, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2014.05.054DOI Listing
August 2014

Monoterpene glycoside ESK246 from Pittosporum targets LAT3 amino acid transport and prostate cancer cell growth.

ACS Chem Biol 2014 Jun 5;9(6):1369-76. Epub 2014 May 5.

Origins of Cancer Laboratory and ‡Gene & Stem Cell Therapy Program, Centenary Institute , Camperdown NSW 2050, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/cb500120xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068216PMC
June 2014

Potent cytotoxic peptides from the Australian marine sponge Pipestela candelabra.

Mar Drugs 2014 Jun 4;12(6):3399-415. Epub 2014 Jun 4.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Queensland 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/md12063399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071583PMC
June 2014

Aplysinellamides A-C, bromotyrosine-derived metabolites from an Australian Aplysinella sp. marine sponge.

J Nat Prod 2014 May 23;77(5):1210-4. Epub 2014 Apr 23.

Eskitis Institute, Griffith University , Brisbane, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/np500119eDOI Listing
May 2014

Natural products as lead structures: chemical transformations to create lead-like libraries.

Drug Discov Today 2014 Mar 27;19(3):215-21. Epub 2013 Oct 27.

Eskitis Institute, Griffith University, Brisbane, QLD 4111, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drudis.2013.10.013DOI Listing
March 2014

Nature Bank and the Queensland Compound Library: unique international resources at the Eskitis Institute for Drug Discovery.

Comb Chem High Throughput Screen 2014 Mar;17(3):201-9

Eskitis Institute for Drug Discovery, Griffith University, Nathan Campus QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1386207317666140109120515DOI Listing
March 2014

N¹,N¹-Dimethyl-N³-(3-(trifluoromethyl)phenethyl)propane-1,3-diamine, a new lead for the treatment of human African trypanosomiasis.

Eur J Med Chem 2014 Mar 9;74:541-51. Epub 2014 Jan 9.

Eskitis Institute for Drug Discovery, Griffith University, Nathan Campus, Brisbane, Queensland 4111, Australia. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S02235234140001
Publisher Site
http://dx.doi.org/10.1016/j.ejmech.2013.12.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296322PMC
March 2014

Chemoinformatic analysis as a tool for prioritization of trypanocidal marine derived lead compounds.

Mar Drugs 2014 Mar 4;12(3):1169-84. Epub 2014 Mar 4.

Eskitis Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/md12031169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967203PMC
March 2014

Dereplication strategies for targeted isolation of new antitrypanosomal actinosporins A and B from a marine sponge associated-Actinokineospora sp. EG49.

Mar Drugs 2014 Mar 6;12(3):1220-44. Epub 2014 Mar 6.

Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, The John Arbuthnott Building, 161 Cathedral Street, Glasgow G4 0NR, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/md12031220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967206PMC
March 2014

Endophytic Streptomyces sp. Y3111 from traditional Chinese medicine produced antitubercular pluramycins.

Appl Microbiol Biotechnol 2014 Feb 5;98(3):1077-85. Epub 2013 Nov 5.

Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100190, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-013-5335-6DOI Listing
February 2014

Cardenolide glycosides from Elaeodendron australe var. integrifolium.

Phytochemistry 2014 Feb 19;98:160-3. Epub 2013 Dec 19.

Eskitis Institute, Griffith University, Brisbane, Queensland 4111, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phytochem.2013.11.024DOI Listing
February 2014

Plasmodium gametocyte inhibition identified from a natural-product-based fragment library.

ACS Chem Biol 2013 Dec 3;8(12):2654-9. Epub 2013 Oct 3.

Eskitis Institute for Drug Discovery, Griffith University , Brisbane, Queensland, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/cb400582bDOI Listing
December 2013

Chemical investigation of an antimalarial Chinese medicinal herb Picrorhiza scrophulariiflora.

Bioorg Med Chem Lett 2013 Nov 27;23(21):5915-8. Epub 2013 Aug 27.

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2013.08.077DOI Listing
November 2013

Trikentramides A-D, indole alkaloids from the Australian sponge Trikentrion flabelliforme.

J Nat Prod 2013 Nov 4;76(11):2100-5. Epub 2013 Nov 4.

Eskitis Institute, Griffith University , Brisbane, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/np400617hDOI Listing
November 2013

Thiaplakortones A-D: antimalarial thiazine alkaloids from the Australian marine sponge Plakortis lita.

J Org Chem 2013 Oct 25;78(19):9608-13. Epub 2013 Sep 25.

Eskitis Institute, Griffith University , Nathan, Queensland 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo400988yDOI Listing
October 2013

ent-Labdane diterpenes from the stems of Mallotus japonicus.

J Nat Prod 2013 Sep 30;76(9):1580-5. Epub 2013 Aug 30.

State Key Laboratory of Drug Research & SIMM-CUHK Joint Research Laboratory for Promoting Globalization of Traditional Chinese Medicines, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 555 Zu-Chong-Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/np400241pDOI Listing
September 2013

Bromotyrosine alkaloids from the Australian marine sponge Pseudoceratina verrucosa.

J Nat Prod 2013 Apr 14;76(4):516-23. Epub 2013 Mar 14.

Eskitis Institute, Griffith University, Brisbane, Queensland 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/np300648dDOI Listing
April 2013

Front-loading natural-product-screening libraries for log P: background, development, and implementation.

Chem Biodivers 2013 Apr;10(4):524-37

Eskitis Institute, Griffith University, Brisbane, Queensland 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cbdv.201200302DOI Listing
April 2013

Cytotoxic cyclic depsipeptides from the Australian marine sponge Neamphius huxleyi.

J Nat Prod 2012 Dec 6;75(12):2200-8. Epub 2012 Dec 6.

Eskitis Institute, Griffith University, Brisbane, Queensland 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/np3006474DOI Listing
December 2012

Unequivocal 13C NMR assignment of cyclohexadienyl rings in bromotyrosine-derived metabolites from marine sponges.

Magn Reson Chem 2012 Nov 10;50(11):749-54. Epub 2012 Sep 10.

Eskitis Institute, Griffith University, Brisbane, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrc.3868DOI Listing
November 2012

Structural insights into the molecular basis of the ligand promiscuity.

J Chem Inf Model 2012 Sep 5;52(9):2410-21. Epub 2012 Sep 5.

UMR 7200 CNRS/Université de Strasbourg, MEDALIS Drug Discovery Center, 74 Route du Rhin, 67401 Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ci300196gDOI Listing
September 2012

Thrombin inhibitors from the freshwater cyanobacterium Anabaena compacta.

J Nat Prod 2012 Sep 5;75(9):1546-52. Epub 2012 Sep 5.

Division of Environmental Materials Science, Graduate School of Environmental Science, Hokkaido University, Sapporo 060-0810, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/np300282aDOI Listing
September 2012

Iotrochamides A and B, antitrypanosomal compounds from the Australian marine sponge Iotrochota sp.

Bioorg Med Chem Lett 2012 Jul 17;22(14):4873-6. Epub 2012 May 17.

Eskitis Institute, Griffith University, Brisbane, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2012.05.029DOI Listing
July 2012

Guiding principles for natural product drug discovery.

Future Med Chem 2012 Jun;4(9):1067-84

Eskitis Institute, Griffith University, Brisbane, Queensland 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4155/fmc.12.55DOI Listing
June 2012

Design and synthesis of screening libraries based on the muurolane natural product scaffold.

Org Biomol Chem 2012 May 15;10(20):4015-23. Epub 2012 Mar 15.

Eskitis Institute, Griffith University, Nathan, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c2ob00029fDOI Listing
May 2012

Ianthelliformisamines A-C, antibacterial bromotyrosine-derived metabolites from the marine sponge Suberea ianthelliformis.

J Nat Prod 2012 May 19;75(5):1001-5. Epub 2012 Apr 19.

Eskitis Institute, Griffith University , Brisbane, QLD 4111, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/np300147dDOI Listing
May 2012