Ronald H A Plasterk

Ronald H A Plasterk

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Ronald H A Plasterk

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Substrate requirements for let-7 function in the developing zebrafish embryo.

Nucleic Acids Res 2016 07 11;44(12):5993. Epub 2016 Mar 11.

The Hubrecht Laboratory, Centre for Biomedical Genetics, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkw173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937305PMC
July 2016

The zebrafish reference genome sequence and its relationship to the human genome.

Authors:
Kerstin Howe Matthew D Clark Carlos F Torroja James Torrance Camille Berthelot Matthieu Muffato John E Collins Sean Humphray Karen McLaren Lucy Matthews Stuart McLaren Ian Sealy Mario Caccamo Carol Churcher Carol Scott Jeffrey C Barrett Romke Koch Gerd-Jörg Rauch Simon White William Chow Britt Kilian Leonor T Quintais José A Guerra-Assunção Yi Zhou Yong Gu Jennifer Yen Jan-Hinnerk Vogel Tina Eyre Seth Redmond Ruby Banerjee Jianxiang Chi Beiyuan Fu Elizabeth Langley Sean F Maguire Gavin K Laird David Lloyd Emma Kenyon Sarah Donaldson Harminder Sehra Jeff Almeida-King Jane Loveland Stephen Trevanion Matt Jones Mike Quail Dave Willey Adrienne Hunt John Burton Sarah Sims Kirsten McLay Bob Plumb Joy Davis Chris Clee Karen Oliver Richard Clark Clare Riddle David Elliot David Eliott Glen Threadgold Glenn Harden Darren Ware Sharmin Begum Beverley Mortimore Beverly Mortimer Giselle Kerry Paul Heath Benjamin Phillimore Alan Tracey Nicole Corby Matthew Dunn Christopher Johnson Jonathan Wood Susan Clark Sarah Pelan Guy Griffiths Michelle Smith Rebecca Glithero Philip Howden Nicholas Barker Christine Lloyd Christopher Stevens Joanna Harley Karen Holt Georgios Panagiotidis Jamieson Lovell Helen Beasley Carl Henderson Daria Gordon Katherine Auger Deborah Wright Joanna Collins Claire Raisen Lauren Dyer Kenric Leung Lauren Robertson Kirsty Ambridge Daniel Leongamornlert Sarah McGuire Ruth Gilderthorp Coline Griffiths Deepa Manthravadi Sarah Nichol Gary Barker Siobhan Whitehead Michael Kay Jacqueline Brown Clare Murnane Emma Gray Matthew Humphries Neil Sycamore Darren Barker David Saunders Justene Wallis Anne Babbage Sian Hammond Maryam Mashreghi-Mohammadi Lucy Barr Sancha Martin Paul Wray Andrew Ellington Nicholas Matthews Matthew Ellwood Rebecca Woodmansey Graham Clark James D Cooper James Cooper Anthony Tromans Darren Grafham Carl Skuce Richard Pandian Robert Andrews Elliot Harrison Andrew Kimberley Jane Garnett Nigel Fosker Rebekah Hall Patrick Garner Daniel Kelly Christine Bird Sophie Palmer Ines Gehring Andrea Berger Christopher M Dooley Zübeyde Ersan-Ürün Cigdem Eser Horst Geiger Maria Geisler Lena Karotki Anette Kirn Judith Konantz Martina Konantz Martina Oberländer Silke Rudolph-Geiger Mathias Teucke Christa Lanz Günter Raddatz Kazutoyo Osoegawa Baoli Zhu Amanda Rapp Sara Widaa Cordelia Langford Fengtang Yang Stephan C Schuster Nigel P Carter Jennifer Harrow Zemin Ning Javier Herrero Steve M J Searle Anton Enright Robert Geisler Ronald H A Plasterk Charles Lee Monte Westerfield Pieter J de Jong Leonard I Zon John H Postlethwait Christiane Nüsslein-Volhard Tim J P Hubbard Hugues Roest Crollius Jane Rogers Derek L Stemple

Nature 2013 Apr 17;496(7446):498-503. Epub 2013 Apr 17.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature12111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703927PMC
April 2013

Proteins interacting with Caenorhabditis elegans Galpha subunits.

Comp Funct Genomics 2003 ;4(5):479-91

Hubrecht Laboratory, Uppsalalaan 8, Utrecht 3584 CT, The Netherlands.

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http://dx.doi.org/10.1002/cfg.318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447299PMC
June 2010

Shotgun cloning of transposon insertions in the genome of Caenorhabditis elegans.

Comp Funct Genomics 2004 ;5(3):225-9

Hubrecht Laboratory, Uppsalalaan 8, Utrecht 3584 CT, The Netherlands.

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http://www.hindawi.com/journals/ijg/2004/569342/abs/
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http://dx.doi.org/10.1002/cfg.392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447444PMC
June 2010

C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging.

PLoS Genet 2008 Mar 21;4(3):e1000027. Epub 2008 Mar 21.

Department of Genetics, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1000027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265412PMC
March 2008

RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans.

EMBO J 2007 Dec 8;26(24):5083-92. Epub 2007 Nov 8.

Department of Physiological Chemistry, Centre for Biomedical Genetics, UMC Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/sj.emboj.7601922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140109PMC
December 2007

Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans.

Nat Struct Mol Biol 2007 Oct 23;14(10):927-33. Epub 2007 Sep 23.

Hubrecht Institute, Koninklijke Nederlandse Akademie van Wetenschappen, Utrecht, 3584 CT, The Netherlands.

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http://dx.doi.org/10.1038/nsmb1308DOI Listing
October 2007

Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway.

Genes Dev 2007 May 16;21(9):1075-85. Epub 2007 Apr 16.

Medical Research Council Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, Scotland, United Kingdom.

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http://dx.doi.org/10.1101/gad.417707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855233PMC
May 2007

Secondary siRNAs result from unprimed RNA synthesis and form a distinct class.

Science 2007 Jan 7;315(5809):244-7. Epub 2006 Dec 7.

Hubrecht Laboratory (NIOB-KNAW), Uppsalalaan 8, 3584 CT, the Netherlands.

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http://dx.doi.org/10.1126/science.1136699DOI Listing
January 2007

Diversity of microRNAs in human and chimpanzee brain.

Nat Genet 2006 Dec 29;38(12):1375-7. Epub 2006 Oct 29.

Hubrecht Laboratory-KNAW, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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https://www.umcg.nl/EN/Research/ERIBA/Documents/Publications
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http://www.nature.com/doifinder/10.1038/ng1914
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December 2006

Mapping determinants of gene expression plasticity by genetical genomics in C. elegans.

PLoS Genet 2006 Dec 13;2(12):e222. Epub 2006 Nov 13.

Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands.

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http://dx.plos.org/10.1371/journal.pgen.0020222
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http://dx.doi.org/10.1371/journal.pgen.0020222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1756913PMC
December 2006

Knocking out the Argonautes.

Cell 2006 Nov;127(4):667-8

Hubrecht Laboratory-KNAW, Utrecht, 3584 CT, The Netherlands.

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http://dx.doi.org/10.1016/j.cell.2006.11.004DOI Listing
November 2006

The diverse functions of microRNAs in animal development and disease.

Dev Cell 2006 Oct;11(4):441-50

Hubrecht Laboratory, Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S153458070600402
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http://dx.doi.org/10.1016/j.devcel.2006.09.009DOI Listing
October 2006

Differences in vertebrate microRNA expression.

Proc Natl Acad Sci U S A 2006 Sep 18;103(39):14385-9. Epub 2006 Sep 18.

Hubrecht Laboratory, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1073/pnas.0603529103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1599972PMC
September 2006

Gene expression: long-term gene silencing by RNAi.

Nature 2006 Aug;442(7105):882

Hubrecht Laboratory-KNAW, University of Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/442882aDOI Listing
August 2006

Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi.

Curr Biol 2006 Jul;16(13):1344-50

Hubrecht Laboratory, Center for Biomedical Genetics, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.cub.2006.05.047DOI Listing
July 2006

Introduction of Double-Stranded RNA in C. elegans by Injection.

CSH Protoc 2006 Jun 1;2006(1). Epub 2006 Jun 1.

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http://dx.doi.org/10.1101/pdb.prot4315DOI Listing
June 2006

Introduction of Double-Stranded RNA in C. elegans by Soaking.

CSH Protoc 2006 Jun 1;2006(1). Epub 2006 Jun 1.

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http://dx.doi.org/10.1101/pdb.prot4316DOI Listing
June 2006

Introduction of Double-Stranded RNA in C. elegans by Feeding.

CSH Protoc 2006 Jun 1;2006(1). Epub 2006 Jun 1.

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http://dx.doi.org/10.1101/pdb.prot4317DOI Listing
June 2006

Cosuppression in C. elegans.

CSH Protoc 2006 Jun 1;2006(1). Epub 2006 Jun 1.

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http://www.cshprotocols.org/lookup/doi/10.1101/pdb.prot4318
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http://dx.doi.org/10.1101/pdb.prot4318DOI Listing
June 2006

Isolation of RNA from C. elegans.

CSH Protoc 2006 Jun 1;2006(1). Epub 2006 Jun 1.

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http://dx.doi.org/10.1101/pdb.prot4321DOI Listing
June 2006

Approaches to microRNA discovery.

Nat Genet 2006 Jun;38 Suppl:S2-7

Hubrecht Laboratory, Uppsalalaan 8, 3584CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/ng1794DOI Listing
June 2006

Cloning and expression of new microRNAs from zebrafish.

Nucleic Acids Res 2006 12;34(9):2558-69. Epub 2006 May 12.

Hubrecht Laboratory, Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkl278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303176PMC
May 2006

Genetic variation in the zebrafish.

Genome Res 2006 Apr 13;16(4):491-7. Epub 2006 Mar 13.

Hubrecht Laboratory, Netherlands Institute for Developmental Biology, 3584CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1101/gr.4791006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1457036PMC
April 2006

Micro RNAs in animal development.

Cell 2006 Mar;124(5):877-81

Hubrecht Laboratory (KNAW), Utrecht University, 3584CT Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.cell.2006.02.030DOI Listing
March 2006

RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain.

RNA 2006 Feb 22;12(2):187-91. Epub 2005 Dec 22.

Division of Neuropathology and Department of Pathology & Laboratory Medicine, University of Pennsylvania School of Medicine, 605A Stellar-Chance Bldg., 421 Curie Blvd., Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1261/rna.2258506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370897PMC
February 2006

In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes.

Nat Methods 2006 Jan;3(1):27-9

Hubrecht Laboratory, Center for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nmeth843DOI Listing
January 2006

MicroRNA function in animal development.

FEBS Lett 2005 Oct 10;579(26):5911-22. Epub 2005 Aug 10.

Hubrecht Laboratory, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://doi.wiley.com/10.1016/j.febslet.2005.07.070
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http://dx.doi.org/10.1016/j.febslet.2005.07.070DOI Listing
October 2005

Camels and zebrafish, viruses and cancer: a microRNA update.

Hum Mol Genet 2005 Oct;14 Spec No. 2:R183-90

Hubrecht Laboratory, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/hmg/ddi271DOI Listing
October 2005

RNA interference spreading in C. elegans.

Methods Enzymol 2005 ;392:308-15

Hubrecht Laboratory, CT Utrecht, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S007668790492018
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http://dx.doi.org/10.1016/S0076-6879(04)92018-6DOI Listing
April 2005

Chromatin and RNAi factors protect the C. elegans germline against repetitive sequences.

Genes Dev 2005 Apr 17;19(7):782-7. Epub 2005 Mar 17.

Hubrecht Laboratory, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1101/gad.332305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1074315PMC
April 2005

Target-selected gene inactivation in zebrafish.

Methods Cell Biol 2004 ;77:69-90

Hubrecht Laboratory, Center for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/s0091-679x(04)77004-1DOI Listing
February 2005

RDE-2 interacts with MUT-7 to mediate RNA interference in Caenorhabditis elegans.

Nucleic Acids Res 2005 13;33(1):347-55. Epub 2005 Jan 13.

Hubrecht Laboratory, Centre for Biomedical Genetics Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/nar/gki183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC546165PMC
February 2005

Substrate requirements for let-7 function in the developing zebrafish embryo.

Nucleic Acids Res 2004 7;32(21):6284-91. Epub 2004 Dec 7.

The Hubrecht Laboratory, Centre for Biomedical Genetics, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkh968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC535676PMC
December 2004

Genomic instability and cancer: scanning the Caenorhabditis elegans genome for tumor suppressors.

Oncogene 2004 Nov;23(51):8366-75

Hubrecht Laboratory, Center for Biomedical Genetics, Uppsalalaan 8, Utrecht 3584 CT, The Netherlands.

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http://dx.doi.org/10.1038/sj.onc.1208011DOI Listing
November 2004

Processing of primary microRNAs by the Microprocessor complex.

Nature 2004 Nov 7;432(7014):231-5. Epub 2004 Nov 7.

Cold Spring Harbor Laboratory, Watson School of Biological Sciences, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.

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http://cancan.cshl.edu/publications/Denli_2004_15531879.pdf
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http://www.nature.com/doifinder/10.1038/nature03049
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http://dx.doi.org/10.1038/nature03049DOI Listing
November 2004

What's new about RNAi? Meeting on siRNAs and miRNAs.

EMBO Rep 2004 Aug 23;5(8):762-5. Epub 2004 Jul 23.

Hubrecht Laboratory, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/sj.embor.7400207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1299118PMC
August 2004

Gene interactions in the DNA damage-response pathway identified by genome-wide RNA-interference analysis of synthetic lethality.

Proc Natl Acad Sci U S A 2004 Aug 23;101(35):12992-6. Epub 2004 Aug 23.

Hubrecht Laboratory, Center for Biomedical Genetics, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1073/pnas.0403131101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC516506PMC
August 2004

RNAi protects the Caenorhabditis elegans germline against transposition.

Trends Genet 2004 Jul;20(7):314-9

The Hubrecht Laboratory and Center for Biomedical Genetics, Uppsalalaan 8, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.tig.2004.04.011DOI Listing
July 2004

Genetic variation in coding regions between and within commonly used inbred rat strains.

Genome Res 2004 Jul;14(7):1285-90

Hubrecht Laboratory, The Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1101/gr.2155004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC442143PMC
July 2004

Single nucleotide polymorphisms associated with rat expressed sequences.

Genome Res 2004 Jul;14(7):1438-43

Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1101/gr.2154304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC442160PMC
July 2004

Dicers at RISC; the mechanism of RNAi.

Cell 2004 Apr;117(1):1-3

Hubrecht Laboratory, Centre for Biomedical Genetics, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/s0092-8674(04)00293-4DOI Listing
April 2004

Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation.

Proc Natl Acad Sci U S A 2004 Apr 14;101(17):6403-8. Epub 2004 Apr 14.

Division of Functional Genomics, Hubrecht Laboratories/Netherlands Institute for Developmental Biology, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1073/pnas.0307697101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC404057PMC
April 2004

Target-selected mutagenesis of the rat.

Genomics 2004 Feb;83(2):332-4

Functional Genomics Group, Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.ygeno.2003.08.010DOI Listing
February 2004

Homologous gene targeting in Caenorhabditis elegans by biolistic transformation.

Nucleic Acids Res 2004 Feb 24;32(4):e40. Epub 2004 Feb 24.

Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gnh033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC390312PMC
February 2004

CONREAL: conserved regulatory elements anchored alignment algorithm for identification of transcription factor binding sites by phylogenetic footprinting.

Genome Res 2004 Jan 12;14(1):170-8. Epub 2003 Dec 12.

Hubrecht Laboratory, Netherlands Institute for Developmental Biology, 3584 CT, Utrecht, The Netherlands.

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http://www.genome.org/cgi/doi/10.1101/gr.1642804
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http://dx.doi.org/10.1101/gr.1642804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC314294PMC
January 2004

Genes required for systemic RNA interference in Caenorhabditis elegans.

Curr Biol 2004 Jan;14(2):111-6

Hubrecht Laboratory, Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.cub.2003.12.029DOI Listing
January 2004

Efficient target-selected mutagenesis in zebrafish.

Genome Res 2003 Dec 12;13(12):2700-7. Epub 2003 Nov 12.

Hubrecht Laboratory, The Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1101/gr.1725103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC403812PMC
December 2003

Characterization of Sleeping Beauty transposition and its application to genetic screening in mice.

Mol Cell Biol 2003 Dec;23(24):9189-207

Collaborative Research Center for Advanced Science and Technology, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC309709PMC
http://dx.doi.org/10.1128/mcb.23.24.9189-9207.2003DOI Listing
December 2003

The microRNA-producing enzyme Dicer1 is essential for zebrafish development.

Nat Genet 2003 Nov 5;35(3):217-8. Epub 2003 Oct 5.

Department of Functional Genomics, Hubrecht Laboratory, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/ng1251DOI Listing
November 2003

Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi.

Nature 2003 Nov;426(6964):310-4

Hubrecht Laboratory, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nature02107DOI Listing
November 2003

The Wnt/beta-catenin pathway regulates cardiac valve formation.

Nature 2003 Oct;425(6958):633-7

Netherlands Institute for Developmental Biology, Hubrecht Laboratory and Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nature02028DOI Listing
October 2003

A micrococcal nuclease homologue in RNAi effector complexes.

Nature 2003 Sep;425(6956):411-4

Cold Spring Harbor Laboratory, Watson School of Biological Sciences, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.

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http://www.nature.com/articles/nature01956
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http://dx.doi.org/10.1038/nature01956DOI Listing
September 2003

Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics.

Nat Biotechnol 2003 Aug 13;21(8):927-31. Epub 2003 Jul 13.

Center for Biomedical Genetics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Sorbonnelaan 16, 3584 CA Utrecht, The Netherlands.

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http://proteome.sysbiol.cam.ac.uk/lecture_and_papers/Papers/
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http://www.nature.com/doifinder/10.1038/nbt848
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http://dx.doi.org/10.1038/nbt848DOI Listing
August 2003

A genome-wide screen identifies 27 genes involved in transposon silencing in C. elegans.

Curr Biol 2003 Aug;13(15):1311-6

Hubrecht Laboratory and Center for Biomedical Genetics, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/s0960-9822(03)00539-6DOI Listing
August 2003

The genetics of RNA silencing.

Annu Rev Genet 2002 11;36:489-519. Epub 2002 Jun 11.

Hubrecht Laboratory, Center for Biomedical Genetics, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1146/annurev.genet.36.043002.091619DOI Listing
July 2003

Continuous exchange of sequence information between dispersed Tc1 transposons in the Caenorhabditis elegans genome.

Genetics 2003 May;164(1):127-34

Hubrecht Laboratory, Center for Biomedical Genetics, 3584 CT Utrecht, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462561PMC
May 2003

Hyperactivation of the G12-mediated signaling pathway in Caenorhabditis elegans induces a developmental growth arrest via protein kinase C.

Curr Biol 2003 Mar;13(6):516-21

Hubrecht Laboratory, Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/s0960-9822(03)00164-7DOI Listing
March 2003

Characterization of Caenorhabditis elegans homologs of the Down syndrome candidate gene DYRK1A.

Genetics 2003 Feb;163(2):571-80

Department of Biochemistry and Molecular Biophysics, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462454PMC
February 2003

X-ray absorption spectroscopic studies of zinc in the N-terminal domain of HIV-2 integrase and model compounds.

J Synchrotron Radiat 2003 Jan 24;10(Pt 1):86-95. Epub 2002 Dec 24.

Department of Organic Chemistry, NSR Center, University of Nijmegen, Toernooiveld, The Netherlands.

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http://dx.doi.org/10.1107/s0909049502016205DOI Listing
January 2003

GENOTRACE: cDNA-based local GENOme assembly from TRACE archives.

Bioinformatics 2002 Oct;18(10):1396-7

Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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October 2002

PPW-1, a PAZ/PIWI protein required for efficient germline RNAi, is defective in a natural isolate of C. elegans.

Curr Biol 2002 Sep;12(17):1535-40

Hubrecht Laboratory, Center for Biomedical Genetics, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/s0960-9822(02)01110-7DOI Listing
September 2002

Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi.

Curr Biol 2002 Aug;12(15):1317-9

Hubrecht Laboratory, Center for Biomedical Genetics, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/s0960-9822(02)01041-2DOI Listing
August 2002

Target-selected inactivation of the zebrafish rag1 gene.

Science 2002 Jul;297(5578):99-102

Hubrecht Laboratory, Center for Biomedical Genetics, Uppsalalaan 8, 3584 CT, Utrecht, Netherlands.

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http://dx.doi.org/10.1126/science.1071762DOI Listing
July 2002

Frequent germline mutations and somatic repeat instability in DNA mismatch-repair-deficient Caenorhabditis elegans.

Genetics 2002 Jun;161(2):651-60

Hubrecht Laboratory, Centre for Biomedical Genetics, 3584 CT, Utrecht, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462132PMC
June 2002

Ronald H.A. Plasterk. Interview by Suzanne Berry.

Trends Biotechnol 2002 May;20(5):224-5

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http://dx.doi.org/10.1016/s0167-7799(02)01958-3DOI Listing
May 2002

RNA silencing: the genome's immune system.

Science 2002 May;296(5571):1263-5

Hubrecht Laboratory, Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, Netherlands.

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http://dx.doi.org/10.1126/science.1072148DOI Listing
May 2002

Functional characterization of the adenylyl cyclase gene sgs-1 by analysis of a mutational spectrum in Caenorhabditis elegans.

Genetics 2002 May;161(1):133-42

Hubrecht Laboratory, Centre for Biomedical Genetics, 3584 CT, Utrecht, The Netherlands.

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May 2002

The G-protein gamma subunit gpc-1 of the nematode C.elegans is involved in taste adaptation.

EMBO J 2002 Mar;21(5):986-94

MGC Department of Cell Biology and Genetics and Centre for Biomedical Genetics, Erasmus University Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125897PMC
March 2002

RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs.

Science 2002 Jan;295(5555):694-7

Hubrecht Laboratory, Center for Biomedical Genetics, Uppsalalaan 8, 3584 CT, Utrecht, Netherlands.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1067534
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January 2002