Ron M A Heeren

Ron M A Heeren

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Ron M A Heeren

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Glutamine deprivation counteracts hypoxia-induced chemoresistance.

Neoplasia 2020 Jan 22;22(1):22-32. Epub 2019 Nov 22.

Department of General, Visceral and Transplantation Surgery, RWTH University Hospital Aachen, Aachen, Germany; Department of Surgery, Maastricht University Medical Center, Maastricht, the Netherlands; ESCAM - European Surgery Center Aachen Maastricht, Aachen, Germany; ESCAM - European Surgery Center Aachen Maastricht, Maastricht, the Netherlands; NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2019.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883317PMC
January 2020

Tissue classification by rapid evaporative ionization mass spectrometry (REIMS): comparison between a diathermic knife and CO laser sampling on classification performance.

Anal Bioanal Chem 2019 Dec 11;411(30):7943-7955. Epub 2019 Nov 11.

Maastricht MultiModal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry, Maastricht University, Universiteitssingel 50, 6229ER, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00216-019-02148-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920236PMC
December 2019

Evaluation of lipid coverage and high spatial resolution MALDI-imaging capabilities of oversampling combined with laser post-ionisation.

Anal Bioanal Chem 2019 Dec 26. Epub 2019 Dec 26.

Maastricht MultiModal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry, Maastricht University, Universiteitssingel 50, 6629, ER, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00216-019-02290-3DOI Listing
December 2019

Maintenance of Deep Lung Architecture and Automated Airway Segmentation for 3D Mass Spectrometry Imaging.

Sci Rep 2019 Dec 27;9(1):20160. Epub 2019 Dec 27.

Department of Microbial Pathogenesis, University of Maryland School of Dentistry, Baltimore, 21201, USA.

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http://dx.doi.org/10.1038/s41598-019-56364-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934789PMC
December 2019

Deciphering Metabolic Heterogeneity by Single-Cell Analysis.

Anal Chem 2019 Nov 8;91(21):13314-13323. Epub 2019 Oct 8.

Medical Systems Biophysics and Bioengineering, Leiden Academic Centre for Drug Research, Faculty of Mathematics and Natural Sciences , Leiden University , Einsteinweg 55 , 2333 CC Leiden , The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.9b02410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922888PMC
November 2019

MALDI-Mass Spectrometry Imaging to Investigate Lipid and Bile Acid Modifications Caused by Lentil Extract Used as a Potential Hypocholesterolemic Treatment.

J Am Soc Mass Spectrom 2019 Oct 5;30(10):2041-2050. Epub 2019 Aug 5.

The Maastricht MultiModal Molecular Imaging Institute (M4I), Division of Imaging Mass Spectrometry, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s13361-019-02265-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805814PMC
October 2019

Cellular resolution in clinical MALDI mass spectrometry imaging: the latest advancements and current challenges.

Clin Chem Lab Med 2019 Oct 30. Epub 2019 Oct 30.

Unit Health, Flemish Institute for Technological Research (VITO), Mol, Belgium.

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http://dx.doi.org/10.1515/cclm-2019-0858DOI Listing
October 2019

MALDI-Mass Spectrometry Imaging to Investigate Lipid and Bile Acid Modifications Caused by Lentil Extract Used as a Potential Hypocholesterolemic Treatment.

J Am Soc Mass Spectrom 2019 Oct;30(10):2041-2050

The Maastricht MultiModal Molecular Imaging Institute (M4I), Division of Imaging Mass Spectrometry , Maastricht University , Maastricht , The Netherlands.

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October 2019

Precise co-registration of mass spectrometry imaging, histology, and laser microdissection-based omics.

Anal Bioanal Chem 2019 Sep 1;411(22):5647-5653. Epub 2019 Jul 1.

Maastricht Multimodal Molecular Imaging Institute (M4I), Maastricht University, Universiteitssingel 50, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00216-019-01983-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704276PMC
September 2019

Ion mobility spectrometry combined with multivariate statistical analysis: revealing the effects of a drug candidate for Alzheimer's disease on Aβ1-40 peptide early assembly.

Anal Bioanal Chem 2019 Sep 12;411(24):6353-6363. Epub 2019 Aug 12.

The Maastricht Multimodal Molecular Imaging institute M4I- Division of Imaging Mass Spectrometry, Maastricht University, Minderbroedersberg 4-6, 6211 LK, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00216-019-02030-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718366PMC
September 2019

Enhanced Sensitivity Using MALDI Imaging Coupled with Laser Postionization (MALDI-2) for Pharmaceutical Research.

Anal Chem 2019 Aug 9;91(16):10840-10848. Epub 2019 Aug 9.

The Maastricht MultiModal Molecular Imaging Institute (M4I), Division of Imaging Mass Spectrometry , Maastricht University , Universiteitssingel 50 , 6229 ER Maastricht , The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.9b02495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706868PMC
August 2019

Trends in mass spectrometry imaging for cardiovascular diseases.

Anal Bioanal Chem 2019 Jul 12;411(17):3709-3720. Epub 2019 Apr 12.

Maastricht MultiModal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00216-019-01780-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594994PMC
July 2019

Mass Spectrometry-Based Tissue Imaging: The Next Frontier in Clinical Diagnostics?

Clin Chem 2019 04 8;65(4):510-513. Epub 2019 Feb 8.

Professor, Department of Chemistry, Purdue University, West Lafayette, IN.

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http://www.clinchem.org/lookup/doi/10.1373/clinchem.2018.289
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http://dx.doi.org/10.1373/clinchem.2018.289694DOI Listing
April 2019

Three-Dimensional Mass Spectrometry Imaging Identifies Lipid Markers of Medulloblastoma Metastasis.

Sci Rep 2019 Feb 18;9(1):2205. Epub 2019 Feb 18.

Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA.

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http://dx.doi.org/10.1038/s41598-018-38257-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379434PMC
February 2019

A patch-based super resolution algorithm for improving image resolution in clinical mass spectrometry.

Sci Rep 2019 Feb 27;9(1):2915. Epub 2019 Feb 27.

Maastricht MultiModal Molecular Imaging institute (M4I), Maastricht, 6229 ER, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-38914-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393664PMC
February 2019

Integrative Clustering in Mass Spectrometry Imaging for Enhanced Patient Stratification.

Proteomics Clin Appl 2019 01 4;13(1):e1800137. Epub 2019 Jan 4.

Maastricht MultiModal Molecular Imaging institute (M4I), Maastricht University, 6229 ER, Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/prca.201800137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590511PMC
January 2019

Tumor classification with MALDI-MSI data of tissue microarrays: A case study.

Methods 2018 12 12;151:21-27. Epub 2018 Apr 12.

The Maastricht MultiModal Molecular Imaging Institute (M4I), Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands; AMOLF, Science Park 104, 1098 XG Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2018.04.004DOI Listing
December 2018

Understanding Detrimental and Beneficial Grain Boundary Effects in Halide Perovskites.

Adv Mater 2018 Dec 26;30(52):e1804792. Epub 2018 Oct 26.

Center for Nanophotonics, AMOLF, Science Park 104, 1098, XG, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/adma.201804792
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http://dx.doi.org/10.1002/adma.201804792DOI Listing
December 2018

Targeted Drug and Metabolite Imaging: Desorption Electrospray Ionization Combined with Triple Quadrupole Mass Spectrometry.

Anal Chem 2018 11 6;90(22):13229-13235. Epub 2018 Nov 6.

Maastricht Multimodal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry , Maastricht University , 6229 ER Maastricht , The Netherlands.

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http://pubs.acs.org/doi/10.1021/acs.analchem.8b03857
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http://dx.doi.org/10.1021/acs.analchem.8b03857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256344PMC
November 2018

Cross-Species Molecular Imaging of Bile Salts and Lipids in Liver: Identification of Molecular Structural Markers in Health and Disease.

Anal Chem 2018 10 4;90(20):11835-11846. Epub 2018 Oct 4.

Maastricht Multimodal Molecular Imaging Institute (M4I) , University of Maastricht , Universiteitssingel 50 , 6229 ER Maastricht , The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.8b01378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193250PMC
October 2018

Round robin study of formalin-fixed paraffin-embedded tissues in mass spectrometry imaging.

Anal Bioanal Chem 2018 Sep 3;410(23):5969-5980. Epub 2018 Jul 3.

The Maastricht MultiModal Molecular Imaging Institute (M4I), Maastricht University, Universiteitssingel 50, Pigeon Hole 57, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00216-018-1216-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096706PMC
September 2018

NF-κB-mediated metabolic remodelling in the inflamed heart in acute viral myocarditis.

Biochim Biophys Acta Mol Basis Dis 2018 Aug 3;1864(8):2579-2589. Epub 2018 May 3.

Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; Department of Physiology, CARIM, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.bbadis.2018.04.022DOI Listing
August 2018

Mass Spectrometry Imaging with Isomeric Resolution Enabled by Ozone-Induced Dissociation.

Angew Chem Int Ed Engl 2018 08 19;57(33):10530-10534. Epub 2018 Jun 19.

M4I, The Maastricht Multimodal Molecular Imaging Institute, Division of Imaging Mass Spectrometry, Maastricht University, Postbus 616, 6200, MD, Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/anie.201802937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100449PMC
August 2018

Identification and High-Resolution Imaging of α-Tocopherol from Human Cells to Whole Animals by TOF-SIMS Tandem Mass Spectrometry.

J Am Soc Mass Spectrom 2018 08 12;29(8):1571-1581. Epub 2018 Jun 12.

M4i, The Maastricht Multi Modal Molecular Imaging Institute, Maastricht University, 6229 ER, Maastricht, The Netherlands.

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http://link.springer.com/10.1007/s13361-018-1979-x
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http://dx.doi.org/10.1007/s13361-018-1979-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060986PMC
August 2018

Digestion-Free Analysis of Peptides from 30-year-old Formalin-Fixed, Paraffin-Embedded Tissue by Mass Spectrometry Imaging.

Anal Chem 2018 08 18;90(15):9272-9280. Epub 2018 Jul 18.

Maastricht MultiModal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry , Maastricht University , Universiteitssingel 50 , 6229ER Maastricht , The Netherlands.

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http://pubs.acs.org/doi/10.1021/acs.analchem.8b01838
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http://dx.doi.org/10.1021/acs.analchem.8b01838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150647PMC
August 2018

Automated, parallel mass spectrometry imaging and structural identification of lipids.

Nat Methods 2018 07 21;15(7):515-518. Epub 2018 May 21.

The Maastricht Multimodal Molecular Imaging Institute (M4I), Division of Imaging Mass Spectrometry, Maastricht University, Maastricht, the Netherlands.

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http://dx.doi.org/10.1038/s41592-018-0010-6DOI Listing
July 2018

Evaluation of Thin-Layer Chromatography-Laser Desorption Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometric Imaging for Visualization of Crude Oil Interactions.

Energy Fuels 2018 Jul 7;32(7):7347-7357. Epub 2018 Jun 7.

Maastricht MultiModal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry, Maastricht University, Maastricht, The Netherlands.

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http://pubs.acs.org/doi/10.1021/acs.energyfuels.8b00639
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http://dx.doi.org/10.1021/acs.energyfuels.8b00639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156098PMC
July 2018

Mass Spectrometry Imaging in Nanomedicine: Unraveling the Potential of MSI for the Detection of Nanoparticles in Neuroscience.

Curr Pharm Des 2017 ;23(13):1974-1984

The Maastricht MultiModal Molecular Imaging Institute, Maastricht University, Universitetitssingel 50, 6229 HX Maastricht, Netherlands.

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http://dx.doi.org/10.2174/1381612823666170111112550DOI Listing
April 2018

Spatial Systems Lipidomics Reveals Nonalcoholic Fatty Liver Disease Heterogeneity.

Anal Chem 2018 04 3;90(8):5130-5138. Epub 2018 Apr 3.

Maastricht Multimodal Molecular Imaging Institute (M4I) , Maastricht University , Universiteitssingel 50 , 6229 ER Maastricht , The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.7b05215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906754PMC
April 2018

Solvent effects on differentiation of mouse brain tissue using laser microdissection 'cut and drop' sampling with direct mass spectral analysis.

Rapid Commun Mass Spectrom 2018 Mar;32(5):414-422

Mass Spectrometry and Laser Spectroscopy Group, Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37831-6131, USA.

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http://dx.doi.org/10.1002/rcm.8053DOI Listing
March 2018

Mass Spectrometry Imaging of Drugs of Abuse in Hair.

Methods Mol Biol 2017 ;1618:137-147

Maastricht Multimodal Molecular Imaging Institute (M4I), University of Maastricht, Universiteitssingel 50, 6229, ER, Maastricht, The Netherlands.

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http://link.springer.com/10.1007/978-1-4939-7051-3_12
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http://dx.doi.org/10.1007/978-1-4939-7051-3_12DOI Listing
February 2018

ToF-SIMS Parallel Imaging MS/MS of Lipid Species in Thin Tissue Sections.

Methods Mol Biol 2017 ;1618:165-173

Maastricht MultiModal Molecular Imaging (M4I) Institute, Maastricht University, Universiteitssingel 50, 6229, ER, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/978-1-4939-7051-3_14DOI Listing
February 2018

Simultaneous lipidomic and transcriptomic profiling in mouse brain punches of acute epileptic seizure model compared to controls.

J Lipid Res 2018 02 5;59(2):283-297. Epub 2017 Dec 5.

University Medical Center of Johannes Gutenberg University Mainz, Institute of Physiological Chemistry, 55128 Mainz, Germany; and

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http://www.jlr.org/lookup/doi/10.1194/jlr.M080093
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http://dx.doi.org/10.1194/jlr.M080093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794423PMC
February 2018

Host-based lipid inflammation drives pathogenesis in infection.

Proc Natl Acad Sci U S A 2017 11 6;114(47):12596-12601. Epub 2017 Nov 6.

Department of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD 21201;

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http://dx.doi.org/10.1073/pnas.1712887114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703311PMC
November 2017

Integration of Ion Mobility MS after Fully Automated, Online, High-Resolution Liquid Extraction Surface Analysis Micro-Liquid Chromatography.

Anal Chem 2017 10 6;89(20):11143-11150. Epub 2017 Oct 6.

Maastricht Multimodal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry, Maastricht University , Maastricht, The Netherlands.

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http://pubs.acs.org/doi/10.1021/acs.analchem.7b03512
Publisher Site
http://dx.doi.org/10.1021/acs.analchem.7b03512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677252PMC
October 2017

Oxygen-Dependent Lipid Profiles of Three-Dimensional Cultured Human Chondrocytes Revealed by MALDI-MSI.

Anal Chem 2017 09 14;89(17):9438-9444. Epub 2017 Aug 14.

The Maastricht Multimodal Molecular Imaging Institute (M4I), Division of Imaging Mass Spectrometry, Maastricht University , 6229 ER Maastricht, The Netherlands.

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http://pubs.acs.org/doi/10.1021/acs.analchem.7b02265
Publisher Site
http://dx.doi.org/10.1021/acs.analchem.7b02265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588094PMC
September 2017

The Composition of Poly(Ethylene Terephthalate) (PET) Surface Precipitates Determined at High Resolving Power by Tandem Mass Spectrometry Imaging.

Microsc Microanal 2017 08 7;23(4):843-848. Epub 2017 Jun 7.

2Maastricht Multi-Modal Molecular Imaging (M4I) Institute,Maastricht University,6211 ER Maastricht,The Netherlands.

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http://dx.doi.org/10.1017/S1431927617000654DOI Listing
August 2017

Sequencing and Identification of Endogenous Neuropeptides with Matrix-Enhanced Secondary Ion Mass Spectrometry Tandem Mass Spectrometry.

Anal Chem 2017 08 3;89(16):8223-8227. Epub 2017 Aug 3.

Maastricht MultiModal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry, Maastricht University , Maastricht, 6229 ER, The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.7b02573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566790PMC
August 2017

Mass spectrometry imaging for clinical research - latest developments, applications, and current limitations.

Analyst 2017 Jul;142(15):2690-2712

Maastricht MultiModal Molecular Imaging (M4I) institute, Division of Imaging Mass Spectrometry, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.

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http://dx.doi.org/10.1039/c7an00565bDOI Listing
July 2017

Efficient Functionalization of Additives at Supramolecular Material Surfaces.

Adv Mater 2017 Feb 29;29(5). Epub 2016 Nov 29.

Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600, MB, Eindhoven, The Netherlands.

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http://dx.doi.org/10.1002/adma.201604652DOI Listing
February 2017

Derivatization Strategies for the Detection of Triamcinolone Acetonide in Cartilage by Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging.

Anal Chem 2016 12 2;88(24):12051-12059. Epub 2016 Dec 2.

The Maastricht Multimodal Molecular Imaging Institute (M4I), Division of Imaging Mass Spectrometry, Maastricht University , Universiteitssingel 50, 6229 ER Maastricht, The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.6b02491DOI Listing
December 2016

Multimodal Spectroscopic Study of Amyloid Fibril Polymorphism.

J Phys Chem B 2016 09 17;120(34):8809-17. Epub 2016 Aug 17.

FOM Institute AMOLF , Science Park 104, 1098 XG Amsterdam, The Netherlands.

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http://dx.doi.org/10.1021/acs.jpcb.6b05339DOI Listing
September 2016

The Impact of N-terminal Acetylation of α-Synuclein on Phospholipid Membrane Binding and Fibril Structure.

J Biol Chem 2016 Sep 16;291(40):21110-21122. Epub 2016 Aug 16.

From the Nanoscale Biophysics Group, FOM Institute AMOLF, Amsterdam, the Nanobiophysics Group, MESA+ Institute for Nanotechnology, University of Twente, Enschede, the Vrije Universiteit Amsterdam, De Boelelaan 1105, 1081 HV Amsterdam, The Netherlands

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http://dx.doi.org/10.1074/jbc.M116.726612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076520PMC
September 2016

Norharmane Matrix Enhances Detection of Endotoxin by MALDI-MS for Simultaneous Profiling of Pathogen, Host, and Vector Systems.

Pathog Dis 2016 Sep 19. Epub 2016 Sep 19.

Department of Microbial Pathogenesis, School of Dentistry, University of Maryland Baltimore, Baltimore, Maryland, USA

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http://dx.doi.org/10.1093/femspd/ftw097DOI Listing
September 2016

Enhanced capabilities for imaging gangliosides in murine brain with matrix-assisted laser desorption/ionization and desorption electrospray ionization mass spectrometry coupled to ion mobility separation.

Methods 2016 07 23;104:69-78. Epub 2016 Feb 23.

M4I, The Maastricht MultiModal Molecular Imaging Institute, University of Maastricht, Maastricht, The Netherlands; FOM-Institute AMOLF, Amsterdam, The Netherlands; TI-COAST, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2016.02.014DOI Listing
July 2016

More from less: high-throughput dual polarity lipid imaging of biological tissues.

Analyst 2016 Jun 4;141(12):3832-41. Epub 2016 Apr 4.

M4I, The Maastricht Multimodal Molecular Imaging Institute, 6229 ER Maastricht, The Netherlands.

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http://dx.doi.org/10.1039/c6an00169fDOI Listing
June 2016

Spatial Autocorrelation in Mass Spectrometry Imaging.

Anal Chem 2016 06 24;88(11):5871-8. Epub 2016 May 24.

Maastricht MultiModal Molecular Imaging Institute (M4I), Maastricht University , Universiteitssingel 50, P.O. Box 616, 6200 MD Maastricht, The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.6b00672DOI Listing
June 2016

A New Method and Mass Spectrometer Design for TOF-SIMS Parallel Imaging MS/MS.

Anal Chem 2016 06 23;88(12):6433-40. Epub 2016 May 23.

Multi-Modal Molecular Imaging (M4I) Institute, Maastricht University , 6211 ER Maastricht, Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.6b01022DOI Listing
June 2016

Mass Spectrometry Imaging of the Hypoxia Marker Pimonidazole in a Breast Tumor Model.

Anal Chem 2016 Mar 29;88(6):3107-14. Epub 2016 Feb 29.

FOM Institute AMOLF , 1098 XG Amsterdam, The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.5b04032DOI Listing
March 2016

An ambient detection system for visualization of charged particles generated with ionization methods at atmospheric pressure.

Rapid Commun Mass Spectrom 2016 Feb;30(3):352-8

FOM Institute AMOLF, Science Park 104, 1098 XG, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/rcm.7442DOI Listing
February 2016

Mass Spectrometry Imaging of Drug Related Crystal-Like Structures in Formalin-Fixed Frozen and Paraffin-Embedded Rabbit Kidney Tissue Sections.

J Am Soc Mass Spectrom 2016 Jan 18;27(1):117-23. Epub 2015 Sep 18.

M4I, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s13361-015-1254-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686544PMC
January 2016

Screening and Quantification of Aliphatic Primary Alkyl Corrosion Inhibitor Amines in Water Samples by Paper Spray Mass Spectrometry.

Anal Chem 2016 Jan 4;88(2):1391-400. Epub 2016 Jan 4.

Department of Chemistry and Biochemistry, The Ohio State University , Columbus, Ohio 43210, United States.

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http://dx.doi.org/10.1021/acs.analchem.5b03992DOI Listing
January 2016

Use of advantageous, volatile matrices enabled by next-generation high-speed matrix-assisted laser desorption/ionization time-of-flight imaging employing a scanning laser beam.

Rapid Commun Mass Spectrom 2015 Dec;29(23):2195-203

M4I, The Maastricht Multimodal Molecular Imaging Institute, 6229 ER Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/rcm.7379DOI Listing
December 2015

Preparation of longitudinal sections of hair samples for the analysis of cocaine by MALDI-MS/MS and TOF-SIMS imaging.

Drug Test Anal 2015 Oct 18;7(10):859-65. Epub 2015 May 18.

FOM-Institute AMOLF, Science Park 104, 1098 XG, Amsterdam, the Netherlands.

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October 2015

Hand-held portable desorption atmospheric pressure chemical ionization ion source for in situ analysis of nitroaromatic explosives.

Anal Chem 2015 Oct 9;87(19):10047-55. Epub 2015 Sep 9.

Chemistry Department, Purdue University , West Lafayette, Indiana 47907, United States.

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http://dx.doi.org/10.1021/acs.analchem.5b02684DOI Listing
October 2015

MALDI-Mass Spectrometric Imaging Revealing Hypoxia-Driven Lipids and Proteins in a Breast Tumor Model.

Anal Chem 2015 Jun 4;87(12):5947-5956. Epub 2015 Jun 4.

Division of Cancer Imaging Research, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820759PMC
June 2015

Direct ion imaging approach for investigation of ion dynamics in multipole ion guides.

Anal Chem 2015 Apr 23;87(7):3714-20. Epub 2015 Mar 23.

†FOM Institute AMOLF, Science Park 104, 1098 XG Amsterdam, The Netherlands.

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http://dx.doi.org/10.1021/ac5041764DOI Listing
April 2015

Differentiation of mesenchymal stem cells under hypoxia and normoxia: lipid profiles revealed by time-of-flight secondary ion mass spectrometry and multivariate analysis.

Anal Chem 2015 Apr 19;87(7):3981-8. Epub 2015 Mar 19.

†Developmental BioEngineering, MIRA Institute for Biomedical Technology and Technical Medicine, Faculty of Science and Technology, University of Twente, 7522 NB Enschede, The Netherlands.

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http://dx.doi.org/10.1021/acs.analchem.5b00114DOI Listing
April 2015

A micropixelated ion-imaging detector for mass resolution enhancement of a QMS instrument.

Anal Bioanal Chem 2015 Mar 1;407(8):2055-62. Epub 2014 Oct 1.

FOM Institute AMOLF, Science Park 104, 1098 XG, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00216-014-8158-0DOI Listing
March 2015

Distributed computing strategies for processing of FT-ICR MS imaging datasets for continuous mode data visualization.

Anal Bioanal Chem 2015 Mar 2;407(8):2321-7. Epub 2014 Oct 2.

FOM Institute AMOLF, Science Park 104, 1098 XG, Amsterdam, The Netherlands,

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March 2015

Discussion point: reporting guidelines for mass spectrometry imaging.

Anal Bioanal Chem 2015 Mar;407(8):2035-45

Center for Proteomics and Metabolomics, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands,

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March 2015

Protein classification and distribution in osteoarthritic human synovial tissue by matrix-assisted laser desorption ionization mass spectrometry imaging.

Anal Bioanal Chem 2015 Mar 13;407(8):2213-22. Epub 2014 Dec 13.

Biomolecular Imaging Mass Spectrometry (BIMS) Department FOM-AMOLF, Science Park 104, 1098 XG, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00216-014-8342-2DOI Listing
March 2015

Mass spectrometry imaging of biological tissue: an approach for multicenter studies.

Anal Bioanal Chem 2015 Mar 10;407(8):2329-35. Epub 2015 Jan 10.

Institute of Inorganic and Analytical Chemistry, Justus Liebig University, Schubertstrasse 60, Bldg. 16, 35392, Giessen, Germany,

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March 2015

Characterization of lipidic markers of chondrogenic differentiation using mass spectrometry imaging.

Proteomics 2015 Feb 3;15(4):702-13. Epub 2015 Jan 3.

Rheumatology Division, ProteoRed/ISCIII Proteomics Group, INIBIC - Hospital Universitario de A Coruña, A Coruña, Spain.

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http://doi.wiley.com/10.1002/pmic.201400260
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February 2015

The use of mass spectrometry imaging to predict treatment response of patient-derived xenograft models of triple-negative breast cancer.

J Proteome Res 2015 Feb 20;14(2):1069-75. Epub 2015 Jan 20.

Biomolecular Imaging Mass Spectrometry, FOM Institute AMOLF , Science Park 104, 1098 XG Amsterdam, The Netherlands.

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http://dx.doi.org/10.1021/pr501067zDOI Listing
February 2015

Experimental investigation of the 2D ion beam profile generated by an ESI octopole-QMS system.

J Am Soc Mass Spectrom 2014 Oct 12;25(10):1780-7. Epub 2014 Aug 12.

FOM Institute AMOLF, Science Park 104, 1098 XG, Amsterdam, The Netherlands.

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October 2014

"Afterlife experiment": use of MALDI-MS and SIMS imaging for the study of the nitrogen cycle within plants.

Anal Chem 2014 Oct 30;86(20):10071-7. Epub 2014 Sep 30.

Biomedical Research Centre, City Campus, Sheffield Hallam University , Howard Street, Sheffield S1 1WB, United Kingdom.

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http://dx.doi.org/10.1021/ac501191wDOI Listing
October 2014

Hydrogen peroxide reactions on cocaine in hair using imaging mass spectrometry.

Forensic Sci Int 2014 Sep 7;242:103-110. Epub 2014 Jul 7.

FOM-Institute AMOLF, Science Park 104, 1098 XG Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.forsciint.2014.06.035DOI Listing
September 2014

Automatic generic registration of mass spectrometry imaging data to histology using nonlinear stochastic embedding.

Anal Chem 2014 Sep 26;86(18):9204-11. Epub 2014 Aug 26.

Division of Image Processing, Department of Radiology, ‡Center for Proteomics and Metabolomics, §Department of Human Genetics, ∥Department of Neurology, and ⊥Department of Pathology, Leiden University Medical Center , 2333 ZA Leiden, The Netherlands.

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http://dx.doi.org/10.1021/ac502170fDOI Listing
September 2014

Gold sputtered fiducial markers for combined secondary ion mass spectrometry and MALDI imaging of tissue samples.

Anal Chem 2014 Jul 25;86(14):6781-5. Epub 2014 Jun 25.

Jozef Stefan Institute , Jamova 39, SI-1000 Ljubljana, Slovenia.

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http://dx.doi.org/10.1021/ac500308sDOI Listing
July 2014

Top-down mass spectrometry imaging of intact proteins by laser ablation ESI FT-ICR MS.

Proteomics 2014 May 12;14(10):1283-9. Epub 2014 Feb 12.

FOM Institute AMOLF, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/pmic.201300306DOI Listing
May 2014

Matrix-assisted laser desorption ionization mass spectrometry imaging for peptide and protein analyses: a critical review of on-tissue digestion.

J Proteome Res 2014 Feb 27;13(2):325-35. Epub 2013 Nov 27.

FOM Institute AMOLF, Biomolecular Imaging Mass Spectrometry (BIMS) , AMOLF Science Park 104, 1098 XG Amsterdam, The Netherlands.

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http://dx.doi.org/10.1021/pr400743aDOI Listing
February 2014

Label-free characterization of biomembranes: from structure to dynamics.

Chem Soc Rev 2014 Feb;43(3):887-900

Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands.

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http://dx.doi.org/10.1039/c3cs60243eDOI Listing
February 2014

A critical evaluation of the current state-of-the-art in quantitative imaging mass spectrometry.

Anal Bioanal Chem 2014 Feb 27;406(5):1275-89. Epub 2013 Nov 27.

FOM Institute AMOLF, Science Park 104, 1098 XG, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00216-013-7478-9DOI Listing
February 2014

MALDI mass spectrometry imaging in microscope mode with infrared lasers: bypassing the diffraction limits.

Anal Chem 2014 Jan 10;86(1):321-5. Epub 2013 Dec 10.

FOM Institute AMOLF , Science Park 104, 1098 XG Amsterdam, The Netherlands.

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http://dx.doi.org/10.1021/ac403421vDOI Listing
January 2014

Absorption mode FTICR mass spectrometry imaging.

Anal Chem 2013 Dec 14;85(23):11180-4. Epub 2013 Nov 14.

FOM Institute AMOLF , Science Park 104, Amsterdam, North Holland, 1098 XG The Netherlands.

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http://dx.doi.org/10.1021/ac403039tDOI Listing
December 2013

Characterization of phosphatidylcholine oxidation products by MALDI MS(n).

Anal Chem 2013 Dec 20;85(23):11410-9. Epub 2013 Nov 20.

Department of Chemistry, University of Florida , Gainesville, Florida 32611-7200, United States.

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December 2013

Cluster secondary ion mass spectrometry microscope mode mass spectrometry imaging.

Rapid Commun Mass Spectrom 2013 Dec;27(24):2745-50

FOM Institute AMOLF, Science Park 104, 1098 XG, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/rcm.6719DOI Listing
December 2013

Multiorder correction algorithms to remove image distortions from mass spectrometry imaging data sets.

Anal Chem 2013 Nov 25;85(21):10249-54. Epub 2013 Oct 25.

Institute of Mathematics, University of Zurich , Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

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http://dx.doi.org/10.1021/ac402018eDOI Listing
November 2013

Enhanced detection of high-mass proteins by using an active pixel detector.

Angew Chem Int Ed Engl 2013 Oct 3;52(43):11261-4. Epub 2013 Sep 3.

Biomolecular Imaging Mass Spectrometry, FOM Institute AMOLF, Science Park 104, 1098 XG Amsterdam (The Netherlands).

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http://dx.doi.org/10.1002/anie.201305501DOI Listing
October 2013

A MASSive laboratory tour. An interactive mass spectrometry outreach activity for children.

J Am Soc Mass Spectrom 2013 Jul 17;24(7):979-82. Epub 2013 May 17.

FOM-Institute AMOLF, Science Park 104, 1098 XG, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s13361-013-0663-4DOI Listing
July 2013

High mass accuracy and high mass resolving power FT-ICR secondary ion mass spectrometry for biological tissue imaging.

Anal Bioanal Chem 2013 Jul 19;405(18):6069-76. Epub 2013 May 19.

FOM Institute AMOLF, Science Park 104, 1098 XG, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00216-013-7048-1DOI Listing
July 2013