Ron H N van Schaik

Ron H N van Schaik

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Ron H N van Schaik

Publications by authors named "Ron H N van Schaik"

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Differences in CYP3A genotypes of a liver transplant recipient and the donor liver graft and adjustment of tacrolimus dose.

Br J Clin Pharmacol 2019 Aug 12;85(8):1852-1854. Epub 2019 Jun 12.

Department of Hospital Pharmacy, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/bcp.13958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624396PMC
August 2019

Donor-derived cell-free DNA detects kidney transplant rejection during nivolumab treatment.

J Immunother Cancer 2019 Jul 12;7(1):182. Epub 2019 Jul 12.

Department of Internal Medicine, Division of Nephrology and Transplantation, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/s40425-019-0653-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626432PMC
July 2019

Serum magnesium, hepatocyte nuclear factor 1β genotype and post-transplant diabetes mellitus: a prospective study.

Nephrol Dial Transplant 2019 Jul 30. Epub 2019 Jul 30.

Department of Internal Medicine, Division of Nephrology & Transplantation, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gfz145DOI Listing
July 2019

Confirmation practice in pharmacogenetic testing; how good is good enough?

Clin Chim Acta 2019 Mar 21;490:77-80. Epub 2018 Dec 21.

Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2018.12.023DOI Listing
March 2019

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.

Authors:
Fredrick R Schumacher Ali Amin Al Olama Sonja I Berndt Sara Benlloch Mahbubl Ahmed Edward J Saunders Tokhir Dadaev Daniel Leongamornlert Ezequiel Anokian Clara Cieza-Borrella Chee Goh Mark N Brook Xin Sheng Laura Fachal Joe Dennis Jonathan Tyrer Kenneth Muir Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis J Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail P Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Håkansson Catharine M L West Alison M Dunning Neil Burnet Lorelei A Mucci Edward Giovannucci Gerald L Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry S Rosenstein Sarah L Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weischer Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Sandeep Singhal Chavdar Slavov Vanio Mitev Matthew Parliament Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Zuxi Cui Peter Kraft Christopher I Amos David V Conti Douglas F Easton Fredrik Wiklund Stephen J Chanock Brian E Henderson Zsofia Kote-Jarai Christopher A Haiman Rosalind A Eeles

Nat Genet 2019 02;51(2):363

Institute of Cancer Research, London, UK.

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http://www.nature.com/articles/s41588-018-0330-6
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http://dx.doi.org/10.1038/s41588-018-0330-6DOI Listing
February 2019

A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy.

Eur J Cancer 2019 Jan 11;107:60-67. Epub 2018 Dec 11.

Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Clinical Pharmacology, Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S09598049183147
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http://dx.doi.org/10.1016/j.ejca.2018.11.010DOI Listing
January 2019

Toward harmonization of clinical molecular diagnostic reports: findings of an international survey.

Clin Chem Lab Med 2018 Dec;57(1):78-88

The Chinese University of Hong Kong, Department of Chemical Pathology, Hong Kong SAR, P.R. China.

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http://dx.doi.org/10.1515/cclm-2017-1080DOI Listing
December 2018

Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants.

Eur J Pharm Sci 2018 Nov 30;124:217-227. Epub 2018 Aug 30.

Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, Wytemaweg 80, 3015CN Rotterdam, the Netherlands; Department of Pharmacology and Toxicology, Radboud University, Geert Grooteplein 21, 6525 EZ Nijmegen, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S09280987183040
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http://dx.doi.org/10.1016/j.ejps.2018.08.042DOI Listing
November 2018

DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis.

Lancet Oncol 2018 11 19;19(11):1459-1467. Epub 2018 Oct 19.

Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam, Netherlands; Department of Clinical Pharmacology, Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183068
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http://dx.doi.org/10.1016/S1470-2045(18)30686-7DOI Listing
November 2018

Individualization of Irinotecan Treatment: A Review of Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics.

Clin Pharmacokinet 2018 10;57(10):1229-1254

Department of Medical Oncology, Erasmus MC Cancer Institute, 's-Gravendijkwal 230, 3015, Rotterdam, The Netherlands.

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http://link.springer.com/10.1007/s40262-018-0644-7
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http://dx.doi.org/10.1007/s40262-018-0644-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132501PMC
October 2018

Liquid Biopsies to Monitor Solid Organ Transplant Function: A Review of New Biomarkers.

Ther Drug Monit 2018 10;40(5):515-525

Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam.

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http://dx.doi.org/10.1097/FTD.0000000000000549DOI Listing
October 2018

No Effect of Dose Adjustment to the Genotype in Patients With Severe Mental Illness.

Front Psychiatry 2018 7;9:349. Epub 2018 Aug 7.

School of Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.

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http://dx.doi.org/10.3389/fpsyt.2018.00349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090167PMC
August 2018

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.

Authors:
Fredrick R Schumacher Ali Amin Al Olama Sonja I Berndt Sara Benlloch Mahbubl Ahmed Edward J Saunders Tokhir Dadaev Daniel Leongamornlert Ezequiel Anokian Clara Cieza-Borrella Chee Goh Mark N Brook Xin Sheng Laura Fachal Joe Dennis Jonathan Tyrer Kenneth Muir Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis J Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail P Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Håkansson Catharine M L West Alison M Dunning Neil Burnet Lorelei A Mucci Edward Giovannucci Gerald L Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry S Rosenstein Sarah L Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weischer Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Sandeep Singhal Chavdar Slavov Vanio Mitev Matthew Parliament Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Zuxi Cui Peter Kraft Christopher I Amos David V Conti Douglas F Easton Fredrik Wiklund Stephen J Chanock Brian E Henderson Zsofia Kote-Jarai Christopher A Haiman Rosalind A Eeles

Nat Genet 2018 07 11;50(7):928-936. Epub 2018 Jun 11.

Institute of Cancer Research, London, UK.

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http://dx.doi.org/10.1038/s41588-018-0142-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568012PMC
July 2018

Enantioselective pharmacokinetics of tramadol and its three main metabolites; impact of , , and genotype.

Pharmacol Res Perspect 2018 07 5;6(4):e00419. Epub 2018 Jul 5.

Department of Forensic Genetics and Forensic Toxicology National Board of Forensic Medicine Linköping Sweden.

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http://dx.doi.org/10.1002/prp2.419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034060PMC
July 2018

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

Authors:
Tokhir Dadaev Edward J Saunders Paul J Newcombe Ezequiel Anokian Daniel A Leongamornlert Mark N Brook Clara Cieza-Borrella Martina Mijuskovic Sarah Wakerell Ali Amin Al Olama Fredrick R Schumacher Sonja I Berndt Sara Benlloch Mahbubl Ahmed Chee Goh Xin Sheng Zhuo Zhang Kenneth Muir Koveela Govindasami Artitaya Lophatananon Victoria L Stevens Susan M Gapstur Brian D Carter Catherine M Tangen Phyllis Goodman Ian M Thompson Jyotsna Batra Suzanne Chambers Leire Moya Judith Clements Lisa Horvath Wayne Tilley Gail Risbridger Henrik Gronberg Markus Aly Tobias Nordström Paul Pharoah Nora Pashayan Johanna Schleutker Teuvo L J Tammela Csilla Sipeky Anssi Auvinen Demetrius Albanes Stephanie Weinstein Alicja Wolk Niclas Hakansson Catharine West Alison M Dunning Neil Burnet Lorelei Mucci Edward Giovannucci Gerald Andriole Olivier Cussenot Géraldine Cancel-Tassin Stella Koutros Laura E Beane Freeman Karina Dalsgaard Sorensen Torben Falck Orntoft Michael Borre Lovise Maehle Eli Marie Grindedal David E Neal Jenny L Donovan Freddie C Hamdy Richard M Martin Ruth C Travis Tim J Key Robert J Hamilton Neil E Fleshner Antonio Finelli Sue Ann Ingles Mariana C Stern Barry Rosenstein Sarah Kerns Harry Ostrer Yong-Jie Lu Hong-Wei Zhang Ninghan Feng Xueying Mao Xin Guo Guomin Wang Zan Sun Graham G Giles Melissa C Southey Robert J MacInnis Liesel M FitzGerald Adam S Kibel Bettina F Drake Ana Vega Antonio Gómez-Caamaño Laura Fachal Robert Szulkin Martin Eklund Manolis Kogevinas Javier Llorca Gemma Castaño-Vinyals Kathryn L Penney Meir Stampfer Jong Y Park Thomas A Sellers Hui-Yi Lin Janet L Stanford Cezary Cybulski Dominika Wokolorczyk Jan Lubinski Elaine A Ostrander Milan S Geybels Børge G Nordestgaard Sune F Nielsen Maren Weisher Rasmus Bisbjerg Martin Andreas Røder Peter Iversen Hermann Brenner Katarina Cuk Bernd Holleczek Christiane Maier Manuel Luedeke Thomas Schnoeller Jeri Kim Christopher J Logothetis Esther M John Manuel R Teixeira Paula Paulo Marta Cardoso Susan L Neuhausen Linda Steele Yuan Chun Ding Kim De Ruyck Gert De Meerleer Piet Ost Azad Razack Jasmine Lim Soo-Hwang Teo Daniel W Lin Lisa F Newcomb Davor Lessel Marija Gamulin Tomislav Kulis Radka Kaneva Nawaid Usmani Chavdar Slavov Vanio Mitev Matthew Parliament Sandeep Singhal Frank Claessens Steven Joniau Thomas Van den Broeck Samantha Larkin Paul A Townsend Claire Aukim-Hastie Manuela Gago-Dominguez Jose Esteban Castelao Maria Elena Martinez Monique J Roobol Guido Jenster Ron H N van Schaik Florence Menegaux Thérèse Truong Yves Akoli Koudou Jianfeng Xu Kay-Tee Khaw Lisa Cannon-Albright Hardev Pandha Agnieszka Michael Andrzej Kierzek Stephen N Thibodeau Shannon K McDonnell Daniel J Schaid Sara Lindstrom Constance Turman Jing Ma David J Hunter Elio Riboli Afshan Siddiq Federico Canzian Laurence N Kolonel Loic Le Marchand Robert N Hoover Mitchell J Machiela Peter Kraft Matthew Freedman Fredrik Wiklund Stephen Chanock Brian E Henderson Douglas F Easton Christopher A Haiman Rosalind A Eeles David V Conti Zsofia Kote-Jarai

Nat Commun 2018 06 11;9(1):2256. Epub 2018 Jun 11.

The Institute of Cancer Research, London, SW7 3RP, UK.

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http://dx.doi.org/10.1038/s41467-018-04109-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995836PMC
June 2018

Pharmacogenetic Information in Clinical Guidelines: The European Perspective.

Clin Pharmacol Ther 2018 05 30;103(5):795-801. Epub 2018 Mar 30.

Department of Clinical Pharmacy & Toxicology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/cpt.1049DOI Listing
May 2018

Accurate determination of the CYP2D6 (*1/*4)xN genotype by quantitative PCR.

Drug Metab Pers Ther 2018 Mar;33(1):33-39

Department of Clinical Chemistry, St Jansdal Hospital, Harderwijk, the Netherlands.

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http://dx.doi.org/10.1515/dmpt-2017-0007DOI Listing
March 2018

Creation of the Swiss group of Pharmacogenomics and personalised Therapy (SPT).

Drug Metab Pers Ther 2017 Dec;32(4):173-174

CANSEARCH Research Laboratory, Geneva University Medical School, Geneva, Switzerland.

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http://dx.doi.org/10.1515/dmpt-2017-0033DOI Listing
December 2017

Effect of Short-Term Fasting on Systemic Cytochrome P450-Mediated Drug Metabolism in Healthy Subjects: A Randomized, Controlled, Crossover Study Using a Cocktail Approach.

Clin Pharmacokinet 2017 10;56(10):1231-1244

Department of Hospital Pharmacy, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40262-017-0515-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591816PMC
October 2017

Reply.

Pain 2017 08;158(8):1623

aDepartment of Clinical Chemistry, Erasmus MC-University Medical Centre Rotterdam, Rotterdam, the Netherlands bIntensive Care and Department of Paediatric Surgery, Erasmus MC-University Medical Centre Rotterdam, Sophia Children's Hospital, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1097/j.pain.0000000000000945DOI Listing
August 2017

A Prospective Population Pharmacokinetic Study on Morphine Metabolism in Cancer Patients.

Clin Pharmacokinet 2017 07;56(7):733-746

Department of Medical Oncology, Erasmus MC Cancer Institute, Groene Hilledijk 301, 3075 EA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40262-016-0471-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5488155PMC
July 2017

Analgesia and Opioids: A Pharmacogenetics Shortlist for Implementation in Clinical Practice.

Clin Chem 2017 Jul;63(7):1204-1213

Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, the Netherlands;

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http://dx.doi.org/10.1373/clinchem.2016.264986DOI Listing
July 2017

Inter-Subject Variability in OCT1 Activity in 27 Batches of Cryopreserved Human Hepatocytes and Association with OCT1 mRNA Expression and Genotype.

Pharm Res 2017 06 31;34(6):1309-1319. Epub 2017 Mar 31.

Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Campus Gasthuisberg O&N II Herestraat 49 Box 921, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1007/s11095-017-2148-9DOI Listing
June 2017

Pre-examination factors affecting molecular diagnostic test results and interpretation: A case-based approach.

Clin Chim Acta 2017 Apr 16;467:59-69. Epub 2016 Jun 16.

Institute for Medical Laboratory Diagnostics, Centre for Clinical and Translational Research (CCTR), HELIOS Hospital, Heusnerstraße 40, 42283 Wuppertal, Witten/Herdecke University, Germany.

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http://dx.doi.org/10.1016/j.cca.2016.06.018DOI Listing
April 2017

CYP2C19 Genotype-Dependent Pharmacokinetic Drug Interaction Between Voriconazole and Ritonavir-Boosted Atazanavir in Healthy Subjects.

J Clin Pharmacol 2017 02 23;57(2):235-246. Epub 2016 Aug 23.

Exploratory Clinical and Translational Research, Bristol-Myers Squibb, Hopewell, NJ, USA.

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http://dx.doi.org/10.1002/jcph.798DOI Listing
February 2017

Prognostic Value of N-Terminal Pro-B-Type Natriuretic Peptide, Troponin-T, and Growth-Differentiation Factor 15 in Adult Congenital Heart Disease.

Circulation 2017 Jan 3;135(3):264-279. Epub 2016 Nov 3.

From Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands (V.J.M.B., A.E.v.d.B., J.A.E., A.-R.W.S., J.A.A.E.C., M.W., F.Z., E.B., J.W.R.-H.); Cardiovascular Research School COEUR, Rotterdam, the Netherlands (V.J.M.B., J.A.E., E.B.); Department of Clinical Chemistry, Erasmus Medical Center, Rotterdam, the Netherlands (M.d.W., R.H.N.v.S.); and Department of Clinical Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands (E.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.023255DOI Listing
January 2017

Genetic variants associated with thermal pain sensitivity in a paediatric population.

Pain 2016 11;157(11):2476-2482

aDepartment of Clinical Chemistry, Erasmus MC-University Medical Centre Rotterdam, Rotterdam, the Netherlands bIntensive Care and Department of Paediatric Surgery, Erasmus MC-University Medical Centre Rotterdam, Sophia Children's Hospital, Rotterdam, the Netherlands cDepartment of Pharmacology and Toxicology, Radboud University Medical Centre, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1097/j.pain.0000000000000664DOI Listing
November 2016

Implication of UGT2B15 Genotype Polymorphism on Postoperative Anxiety Levels in Patients Receiving Lorazepam Premedication.

Anesth Analg 2016 11;123(5):1109-1115

From the Departments of *Anesthesiology and †Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1213/ANE.0000000000001508DOI Listing
November 2016

The Effect of Roux-en-Y Gastric Bypass Surgery in Morbidly Obese Patients on Pharmacokinetics of (Acetyl)Salicylic Acid and Omeprazole: the ERY-PAO Study.

Obes Surg 2016 09;26(9):2051-2058

Department of Clinical Pharmacy and Pharmacology, University Medical Centre Groningen Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s11695-016-2065-8DOI Listing
September 2016

The Effect of Weight and CYP3A5 Genotype on the Population Pharmacokinetics of Tacrolimus in Stable Paediatric Renal Transplant Recipients.

Clin Pharmacokinet 2016 09;55(9):1129-43

Department of Hospital Pharmacy-Clinical Pharmacology Unit, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40262-016-0390-7DOI Listing
September 2016

Genetic Predisposition to Poor Opioid Response in Preterm Infants: Impact of KCNJ6 and COMT Polymorphisms on Pain Relief After Endotracheal Intubation.

Ther Drug Monit 2016 08;38(4):525-33

*Department Clinical Chemistry, Erasmus University Medical Center, Rotterdam, the Netherlands; †Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium; ‡Unit of Pediatrics, Department of Clinical Sciences, Lund, Lund University and Skåne University Hospital, Lund, Sweden; §Department of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska Institutet at Karolinska University Hospital, Huddinge, Stockholm, Sweden; and ¶Children's Hospital, University of Helsinki and Helsinki University Hospital, Finland.

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http://dx.doi.org/10.1097/FTD.0000000000000301DOI Listing
August 2016

SLC22A1/OCT1 Genotype Affects O-desmethyltramadol Exposure in Newborn Infants.

Ther Drug Monit 2016 08;38(4):487-92

*Department of Clinical Chemistry, Erasmus University Medical Centre; Departments of †Intensive Care and ‡Paediatric Surgery, Sophia Children's Hospital, Erasmus University Medical Centre, Rotterdam, the Netherlands; §Integrated PharmacoMetrics, PharmacoGenomics and PharmacoKinetics, Louvain Drug Research Institute, Université Catholique de Louvain, Brussels; ¶Center for Clinical Pharmacology, University Hospitals Leuven & Department of Pharmaceutical and Pharmacological Sciences, University Hospitals; ‖Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven; and **Neonatal Intensive Care Unit, University Hospitals, Leuven, Belgium.

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http://dx.doi.org/10.1097/FTD.0000000000000307DOI Listing
August 2016

Population Pharmacokinetics of Prednisolone in Relation to Clinical Outcome in Children With Nephrotic Syndrome.

Ther Drug Monit 2016 08;38(4):534-45

*Department of Pediatrics, Division of Nephrology, Erasmus University Medical Centre, Sophia Children's Hospital, Rotterdam; †Centre for Human Drug Research, Leiden; ‡Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Centre; §Department of Clinical Chemistry, Laboratory of Endocrinology, Academic Medical Center, Amsterdam; Departments of ¶Clinical Chemistry, ‖Internal Medicine, and **Hospital Pharmacy, Erasmus University Medical Centre, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1097/FTD.0000000000000308DOI Listing
August 2016

Predicting paclitaxel-induced neutropenia using the DMET platform.

Pharmacogenomics 2015 12;16(11):1231-41. Epub 2015 Aug 12.

Department of Clinical Chemistry, Erasmus University Medical Center, s-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands.

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http://dx.doi.org/10.2217/pgs.15.68DOI Listing
June 2016

Elevated Plasma Cardiac Troponin T Levels Caused by Skeletal Muscle Damage in Pompe Disease.

Circ Cardiovasc Genet 2016 Feb 19;9(1):6-13. Epub 2016 Jan 19.

From the Department of Neurology (S.C.A.W., E.B., P.A.v.D.), Center for Lysosomal and Metabolic Diseases (S.C.A.W., G.J.S., M.E.K., T.J.M.v.G., S.G., J.P., E.B., A.T.v.d.P., P.A.v.D., W.W.M.P.P.), Molecular Stem Cell Biology, Department of Clinical Genetics (G.J.S., T.J.M.v.G., S.G., J.P., W.W.M.P.P.), Department of Cardiology (M.M.), Department of Clinical Chemistry (R.H.N.v.S.), Erasmus MC University Medical Center, Rotterdam, The Netherlands; Division of Metabolic Diseases and Genetics, Department of Pediatrics, Erasmus MC-Sophia, Rotterdam, The Netherlands (G.J.S., T.J.M.v.G., S.G., J.P., A.T.v.d.P., W.W.M.P.P.); Proteomics Center, Erasmus MC University Medical Center, Rotterdam, The Netherlands (D.H.W.D., J.A.A.D.); Netherlands Proteomics Center, Rotterdam, The Netherlands (D.H.W.D., J.A.A.D.); and NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands (L.B.V.).

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February 2016

4β-hydroxycholesterol as an endogenous CYP3A marker in cancer patients treated with taxanes.

Br J Clin Pharmacol 2015 Sep 12;80(3):560-8. Epub 2015 Aug 12.

Department of Clinical Chemistry, Erasmus University Medical Center, 's-Gravendijkwal 230, 3015CE, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1111/bcp.12707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574840PMC
September 2015

The Effect of Tamoxifen Dose Increment in Patients With Impaired CYP2D6 Activity.

Ther Drug Monit 2015 Aug;37(4):501-7

*Department of Pharmacy, Radboud University Medical Center, Nijmegen; †Department of Clinical Oncology; ‡Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center; §Department of Clinical Chemistry, Erasmus Medical Center, Rotterdam; ¶Department of Medical Oncology, Radboud University Medical Center, Nijmegen; and ‖Department of Medical Oncology, Academic Medical Center, University of Amsterdam, the Netherlands.

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http://dx.doi.org/10.1097/FTD.0000000000000195DOI Listing
August 2015

Effect of UGT2B7 -900G>A (-842G>A; rs7438135) on morphine glucuronidation in preterm newborns: results from a pilot cohort.

Pharmacogenomics 2014 ;15(12):1589-97

Department Clinical Chemistry, Erasmus MC - University Medical Center Rotterdam, The Netherlands.

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http://dx.doi.org/10.2217/pgs.14.115DOI Listing
June 2015

Pharmacokinetically based dosing of weekly paclitaxel to reduce drug-related neurotoxicity based on a single sample strategy.

Cancer Chemother Pharmacol 2015 May 12;75(5):975-83. Epub 2015 Mar 12.

Institute of Pharmacy, Clinical Pharmacy, University of Bonn, An der Immenburg 4, 53121, Bonn, Germany.

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May 2015

High-sensitive troponin-T in adult congenital heart disease.

Int J Cardiol 2015 Apr 25;184:405-11. Epub 2015 Feb 25.

Department of cardiology, Thorax Center, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ijcard.2015.02.027DOI Listing
April 2015

POR*28 SNP is associated with lipid response to atorvastatin in children and adolescents with familial hypercholesterolemia.

Pharmacogenomics 2014 Dec;15(16):1963-72

Unit of Metabolic Diseases, 1st Department of Pediatrics, Choremio Research Laboratory, Aghia Sophia Children's Hospital, Medical School, University of Athens, Athens, Greece.

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http://dx.doi.org/10.2217/pgs.14.138DOI Listing
December 2014

Do Asian renal transplant patients need another mycophenolate mofetil dose compared with Caucasian or African American patients?

Transpl Int 2014 Oct 22;27(10):994-1004. Epub 2014 Aug 22.

Department of Hospital Pharmacy, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands; Department of Pharmacy, China-Japan Friendship Hospital, Beijing, China.

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http://dx.doi.org/10.1111/tri.12382DOI Listing
October 2014

Genetic variance in ABCB1 and CYP3A5 does not contribute toward the development of chronic kidney disease after liver transplantation.

Pharmacogenet Genomics 2014 Sep;24(9):427-35

Departments of aGastroenterology and Hepatology bInternal Medicine cClinical Chemistry dSurgery eHospital Pharmacy, Clinical Pharmacology Unit; Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/FPC.0000000000000063DOI Listing
September 2014

New challenges for pharmacogenomics.

Drug Metabol Drug Interact 2013 ;28(4):191-2

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http://dx.doi.org/10.1515/dmdi-2013-0060DOI Listing
August 2014

Using tramadol to measure CYP2D6 metabolism in critically ill adults.

Intensive Care Med 2014 Aug 27;40(8):1177-8. Epub 2014 Jun 27.

Division of Clinical Sciences: Intensive Care, St George's, University of London, London, SW17 0RE, UK,

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http://link.springer.com/10.1007/s00134-014-3372-y
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August 2014

No association between CYP3A4*22 and statin effectiveness in reducing the risk for myocardial infarction.

Pharmacogenomics 2014 Aug;15(11):1471-7

Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

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https://www.futuremedicine.com/doi/10.2217/pgs.14.90
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August 2014

Rescue morphine in mechanically ventilated newborns associated with combined OPRM1 and COMT genotype.

Pharmacogenomics 2014 Jul;15(10):1287-95

Department of Clinical Chemistry, Erasmus MC - University Medical Center Rotterdam, The Netherlands.

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http://dx.doi.org/10.2217/pgs.14.100DOI Listing
July 2014

Genetic polymorphisms in IL-2, IL-10, TGF-β1, and IL-2RB and acute rejection in renal transplant patients.

Clin Transplant 2014 Jun 3;28(6):649-55. Epub 2014 Jun 3.

Department of Hospital Pharmacy, Erasmus MC, Rotterdam, The Netherlands; Department of Hospital Pharmacy, Beijing Jishuitan Hospital, Beijing, China.

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http://dx.doi.org/10.1111/ctr.12346DOI Listing
June 2014

Personalized pharmacogenomics profiling using whole-genome sequencing.

Pharmacogenomics 2014 Jun;15(9):1223-34

Laboratory of Molecular Genetics, Department of Physiology & Biochemistry, University of Malta, Msida, Malta.

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http://dx.doi.org/10.2217/pgs.14.102DOI Listing
June 2014

Calcineurin inhibitors and hypertension: a role for pharmacogenetics?

Pharmacogenomics 2014 Jun;15(9):1243-51

Department of Internal Medicine, Nephrology & Transplantation, Erasmus  Medical Center, PO Box 2040 - Room H-438, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.2217/pgs.14.87DOI Listing
June 2014

P450 oxidoreductase *28 (POR*28) and tacrolimus disposition in pediatric kidney transplant recipients--a pilot study.

Ther Drug Monit 2014 Apr;36(2):152-8

*Intensive Care and Department of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands; †Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, ON, Canada; ‡Department of Clinical Chemistry, Erasmus MC, Rotterdam, The Netherlands; Departments of §Oncology; ¶Medicine; ‖Pharmacology; **Physiology; ††Biophysics, Georgetown University Medical Center, Washington, DC; and ‡‡Department of Medicine, University of Western Ontario, London, ON, Canada.

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http://dx.doi.org/10.1097/FTD.0b013e3182a3f282DOI Listing
April 2014

Clinical implementation of pharmacogenetics in kidney transplantation: calcineurin inhibitors in the starting blocks.

Br J Clin Pharmacol 2014 Apr;77(4):715-28

Louvain Drug Research Institute (LDRI), Université Catholique de Louvain (UCL), Brussels, Belgium; Department of Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam.

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http://doi.wiley.com/10.1111/bcp.12253
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http://dx.doi.org/10.1111/bcp.12253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971987PMC
April 2014

A guide to the current Web-based resources in pharmacogenomics.

Methods Mol Biol 2013 ;1015:293-310

Queensland Institute of Medical Research, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1007/978-1-62703-435-7_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795434PMC
February 2014

Evidence based drug dosing and pharmacotherapeutic recommendations per genotype.

Methods Mol Biol 2013 ;1015:345-54

Department of Clinical Pharmacy, St. Antonius Ziekenhuis Nieuwegein, Nieuwegein, The Netherlands.

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http://dx.doi.org/10.1007/978-1-62703-435-7_23DOI Listing
February 2014

Impact of POR*28 on the pharmacokinetics of tacrolimus and cyclosporine A in renal transplant patients.

Ther Drug Monit 2014 Feb;36(1):71-9

*Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, the Netherlands; †Louvain Centre for Toxicology and Applied Pharmacology (LTAP) Department, Université catholique de Louvain, Brussels, Belgium; ‡Department of Internal Medicine and §Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, the Netherlands; ¶Department of Nephrology, Charite University, Berlin, Germany; ‖Department of Nephrology, Leiden University Medical Centre, Leiden, the Netherlands; **Surgery and Abdominal Transplantation Unit Cliniques universitaires St Luc, Université catholique de Louvain, Brussels, Belgium; and ††Department of Nephrology, University of Leuven, Leuven, Belgium.

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http://pdfs.journals.lww.com/drug-monitoring/2014/02000/Impa
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http://dx.doi.org/10.1097/FTD.0b013e31829da6ddDOI Listing
February 2014

The role of pharmacogenetics in the disposition of and response to tacrolimus in solid organ transplantation.

Clin Pharmacokinet 2014 Feb;53(2):123-39

Division of Nephrology and Renal Transplantation, Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Room D-427, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands,

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http://link.springer.com/10.1007/s40262-013-0120-3
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February 2014

Single-nucleotide polymorphisms in P450 oxidoreductase and peroxisome proliferator-activated receptor-α are associated with the development of new-onset diabetes after transplantation in kidney transplant recipients treated with tacrolimus.

Pharmacogenet Genomics 2013 Dec;23(12):649-57

Departments of aClinical Chemistry bHospital Pharmacy cInternal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam dDepartment of Hospital Pharmacy, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands eLouvain Centre for Toxicology and Applied Pharmacology (LTAP), Institute for Clinical and Experimental Researches (IREC), Catholic University of Louvain (UCL), Brussels, Belgium.

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http://dx.doi.org/10.1097/FPC.0000000000000001DOI Listing
December 2013

Hot flashes are not predictive for serum concentrations of tamoxifen and its metabolites.

BMC Cancer 2013 Dec 28;13:612. Epub 2013 Dec 28.

Department of Pharmacy & Pharmacology, Slotervaart Hospital/The Netherlands Cancer Institute, Louwesweg 6, 1066 EC Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/1471-2407-13-612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880169PMC
December 2013

Impact of CYP3A4*22 allele on tacrolimus pharmacokinetics in early period after renal transplantation: toward updated genotype-based dosage guidelines.

Ther Drug Monit 2013 Oct;35(5):608-16

*Louvain centre for Toxicology and Applied Pharmacology, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium; †Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands; and ‡Laboratory of Analytical Biochemistry, §Surgery and Abdominal Transplantation Division, and ¶Laboratory of Immuno-haematology, Cliniques universitaires St Luc, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.1097/FTD.0b013e318296045bDOI Listing
October 2013

A pharmacogenetic predictive model for paclitaxel clearance based on the DMET platform.

Clin Cancer Res 2013 Sep 5;19(18):5210-7. Epub 2013 Aug 5.

Authors' Affiliations: Departments of Medical Oncology, Clinical Chemistry, and Trials and Statistics, Erasmus University Medical Center, Erasmus MC Cancer Institute, Rotterdam, the Netherlands; Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, Tennessee; and Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0487DOI Listing
September 2013

Genetic polymorphisms in ABCB1 influence the pharmacodynamics of tacrolimus.

Ther Drug Monit 2013 Aug;35(4):459-65

Department of Internal Medicine, University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1097/FTD.0b013e31828c1581DOI Listing
August 2013

CYP3A4*22: promising newly identified CYP3A4 variant allele for personalizing pharmacotherapy.

Pharmacogenomics 2013 Jan;14(1):47-62

Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.2217/pgs.12.187DOI Listing
January 2013

CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin.

Pharmacogenomics 2013 Jan;14(2):137-49

Department of Clinical Chemistry, Erasmus University Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.2217/pgs.12.202DOI Listing
January 2013

Pharmacogenetics in kidney transplantation: recent updates and potential clinical applications.

Mol Diagn Ther 2012 Dec;16(6):331-45

Department of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40291-012-0012-5DOI Listing
December 2012

ABCB1 and ABCC3 gene polymorphisms are associated with first-year response to methotrexate in juvenile idiopathic arthritis.

J Rheumatol 2012 Oct 1;39(10):2032-40. Epub 2012 Aug 1.

Department of Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.3899/jrheum.111593DOI Listing
October 2012

Multi-center analytical performance evaluation of the Access Hybritech® p2PSA immunoassay.

Clin Chim Acta 2012 Aug 20;413(15-16):1279-83. Epub 2012 Apr 20.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, United States.

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http://dx.doi.org/10.1016/j.cca.2012.04.015DOI Listing
August 2012