Ron A A Mathôt

Ron A A Mathôt

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Ron A A Mathôt

Ron A A Mathôt

Publications by authors named "Ron A A Mathôt"

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The effects of fasting on drug metabolism.

Expert Opin Drug Metab Toxicol 2020 Jan 24;16(1):79-85. Epub 2019 Dec 24.

Department of Medicine, Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1080/17425255.2020.1706728DOI Listing
January 2020

Efficacy and safety of FOLFIRINOX as salvage treatment in advanced biliary tract cancer: an open-label, single arm, phase 2 trial.

Br J Cancer 2020 Jan 10. Epub 2020 Jan 10.

Amsterdam UMC, Department of Medical Oncology, University of Amsterdam, Cancer Center Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41416-019-0698-9DOI Listing
January 2020

Tumor necrosis factor-mediated disposition of infliximab in ulcerative colitis patients.

J Pharmacokinet Pharmacodyn 2019 Dec 5;46(6):543-551. Epub 2019 Sep 5.

Hospital Pharmacy, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10928-019-09652-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868113PMC
December 2019

Pharmacokinetics and population pharmacokinetics in pediatric oncology.

Pediatr Blood Cancer 2019 Dec 25:e28132. Epub 2019 Dec 25.

Department of Hospital Pharmacy, Amsterdam University Medical Centers, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/pbc.28132DOI Listing
December 2019

Differential effects of a 40-hour fast and bile acid supplementation on human GLP-1 and FGF19 responses.

Am J Physiol Endocrinol Metab 2019 Sep 25;317(3):E494-E502. Epub 2019 Jun 25.

Department of Endocrinology and Metabolism, Amsterdam University Medical Centers, The Netherlands.

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http://dx.doi.org/10.1152/ajpendo.00534.2018DOI Listing
September 2019

Population Pharmacokinetics of Ganciclovir in Critically Ill Patients.

Ther Drug Monit 2019 Aug 16. Epub 2019 Aug 16.

Department of Hospital Pharmacy, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/FTD.0000000000000689DOI Listing
August 2019

External Evaluation of Population Pharmacokinetic Models of Vancomycin in Large Cohorts of Intensive Care Unit Patients.

Antimicrob Agents Chemother 2019 05 25;63(5). Epub 2019 Apr 25.

Department of Intensive Care Medicine, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Amsterdam Medical Data Science (AMDS), Research VUmc Intensive Care (REVIVE), Amsterdam Cardiovascular Sciences (ACS), Amsterdam, The Netherlands.

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http://dx.doi.org/10.1128/AAC.02543-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496102PMC
May 2019

Strategies for Individualized Dosing of Clotting Factor Concentrates and Desmopressin in Hemophilia A and B.

Ther Drug Monit 2019 04;41(2):192-212

Department of Hospital Pharmacy-Clinical Pharmacology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1097/FTD.0000000000000625DOI Listing
April 2019

Population Pharmacokinetics with Monte Carlo Simulations of Gentamicin in a Population of Severely Ill Adult Patients from Sub-Saharan Africa.

Antimicrob Agents Chemother 2019 04 27;63(4). Epub 2019 Mar 27.

Amsterdam UMC, University of Amsterdam, Department of Hospital Pharmacy, Division of Clinical Pharmacology, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1128/AAC.02328-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437512PMC
April 2019

Strategies for individualized dosing of clotting factor concentrates and desmopressin in hemophilia A and B.

Ther Drug Monit 2019 Feb 26. Epub 2019 Feb 26.

Hospital Pharmacy-Clinical Pharmacology, Amsterdam UMC, University of Amsterdam, the Netherlands.

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http://dx.doi.org/10.1097/FTD.0000000000000625DOI Listing
February 2019

Clinical Pharmacokinetic and Pharmacodynamic Considerations in the Treatment of Ulcerative Colitis.

Clin Pharmacokinet 2019 01;58(1):15-37

Department Hospital Pharmacy, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40262-018-0676-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326086PMC
January 2019

Combining Brain Microdialysis and Translational Pharmacokinetic Modeling to Predict Drug Concentrations in Pediatric Severe Traumatic Brain Injury: The Next Step Toward Evidence-Based Pharmacotherapy?

J Neurotrauma 2019 01 6;36(1):111-117. Epub 2018 Sep 6.

3 Division of Neurosurgery and Neuroscience Institute, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1089/neu.2017.5588DOI Listing
January 2019

Nutritional Status Differentially Alters Cytochrome P450 3A4 (CYP3A4) and Uridine 5'-Diphospho-Glucuronosyltransferase (UGT) Mediated Drug Metabolism: Effect of Short-Term Fasting and High Fat Diet on Midazolam Metabolism.

Eur J Drug Metab Pharmacokinet 2018 Dec;43(6):751-767

Department of Hospital Pharmacy, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s13318-018-0487-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244726PMC
December 2018

Positioning extended half-life concentrates for future use: a practical proposal.

Haemophilia 2018 09 24;24(5):e369-e372. Epub 2018 Aug 24.

Department of Paediatric Haematology, Erasmus University Medical Centre - Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/hae.13588DOI Listing
September 2018

Pharmacokinetics and pharmacodynamic target attainment of ceftriaxone in adult severely ill sub-Saharan African patients: a population pharmacokinetic modelling study.

J Antimicrob Chemother 2018 06;73(6):1620-1629

Academic Medical Centre (AMC), University of Amsterdam, Department of Hospital Pharmacy, Division of Clinical Pharmacology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/jac/dky071DOI Listing
June 2018

Short-Term Fasting Alters Pharmacokinetics of Cytochrome P450 Probe Drugs: Does Protein Binding Play a Role?

Eur J Drug Metab Pharmacokinet 2018 Apr;43(2):251-257

Department of Hospital Pharmacy, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s13318-017-0437-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854751PMC
April 2018

Pharmacokinetics and Pharmacodynamic Target Attainment of Benzylpenicillin in an Adult Severely Ill Sub-Saharan African Patient Population.

Clin Infect Dis 2018 04;66(8):1261-1269

Department of Internal Medicine, Division of Infectious Diseases, Academic Medical Center, University of Amsterdam, The Netherlands.

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https://academic.oup.com/cid/article/66/8/1261/4588729
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http://dx.doi.org/10.1093/cid/cix961DOI Listing
April 2018

Pharmacokinetic Modelling to Predict FVIII:C Response to Desmopressin and Its Reproducibility in Nonsevere Haemophilia A Patients.

Thromb Haemost 2018 04 19;118(4):621-629. Epub 2018 Feb 19.

Department of Hospital Pharmacy, Academic Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1160/TH17-06-0390DOI Listing
April 2018

Population pharmacodynamic modelling of midazolam induced sedation in terminally ill adult patients.

Br J Clin Pharmacol 2018 02 26;84(2):320-330. Epub 2017 Oct 26.

Hospital Pharmacy - Clinical Pharmacology, Academic Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/bcp.13442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777431PMC
February 2018

CNS penetration of ART in HIV-infected children.

J Antimicrob Chemother 2018 02;73(2):484-489

Department of Pediatric Infectious Diseases, Emma Children's Hospital/Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/jac/dkx396DOI Listing
February 2018

Paracetamol clinical dosing routine leads to paracetamol underexposure in an adult severely ill sub-Saharan African hospital population: a drug concentration measurement study.

BMC Res Notes 2017 Dec 4;10(1):671. Epub 2017 Dec 4.

Division of Infectious Diseases, Department of Internal Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13104-017-3016-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715499PMC
December 2017

Pharmacokinetics of S-ketamine during prolonged sedation at the pediatric intensive care unit.

Paediatr Anaesth 2017 Nov;27(11):1098-1107

Department of Hospital Pharmacy, Academic Medical Center, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1111/pan.13239
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http://dx.doi.org/10.1111/pan.13239DOI Listing
November 2017

Effect of Short-Term Fasting on Systemic Cytochrome P450-Mediated Drug Metabolism in Healthy Subjects: A Randomized, Controlled, Crossover Study Using a Cocktail Approach.

Clin Pharmacokinet 2017 10;56(10):1231-1244

Department of Hospital Pharmacy, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40262-017-0515-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591816PMC
October 2017

Hypoalbuminaemia and decreased midazolam clearance in terminally ill adult patients, an inflammatory effect?

Br J Clin Pharmacol 2017 08 31;83(8):1701-1712. Epub 2017 Mar 31.

Hospital Pharmacy - Clinical Pharmacology, Academic Medical Centre, Amsterdam, Netherlands.

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http://dx.doi.org/10.1111/bcp.13259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510071PMC
August 2017

Population pharmacokinetics of intravenous clonidine for sedation during paediatric extracorporeal membrane oxygenation and continuous venovenous hemofiltration.

Br J Clin Pharmacol 2017 06 27;83(6):1227-1239. Epub 2017 Feb 27.

Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, P.O. Box 2060, 3000, CB, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/bcp.13235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427246PMC
June 2017

Quantitative Method for Simultaneous Analysis of Acetaminophen and 6 Metabolites.

Ther Drug Monit 2017 04;39(2):172-179

Departments of *Hospital Pharmacy and †Medicine, Academic Medical Center, Amsterdam, the Netherlands.

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http://Insights.ovid.com/crossref?an=00007691-201704000-0001
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http://dx.doi.org/10.1097/FTD.0000000000000373DOI Listing
April 2017

Determinants of gentamicin concentrations in critically ill patients: a population pharmacokinetic analysis.

Int J Antimicrob Agents 2017 Feb 16;49(2):204-211. Epub 2016 Dec 16.

Department of Hospital Pharmacy & Clinical Pharmacology, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ijantimicag.2016.10.022DOI Listing
February 2017

Population Pharmacokinetics and Dosing Considerations for Gentamicin in Newborns with Suspected or Proven Sepsis Caused by Gram-Negative Bacteria.

Antimicrob Agents Chemother 2017 01 27;61(1). Epub 2016 Dec 27.

Department of Neonatology, Emma Children's Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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http://aac.asm.org/lookup/doi/10.1128/AAC.01304-16
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http://dx.doi.org/10.1128/AAC.01304-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192127PMC
January 2017

Quantitative Method for Simultaneous Analysis of a 5-Probe Cocktail for Cytochrome P450 Enzymes.

Ther Drug Monit 2016 12;38(6):761-768

Departments of *Hospital Pharmacy, †Medicine, ‡Endocrinology and Metabolism, and §Medical Oncology, Academic Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1097/FTD.0000000000000338DOI Listing
December 2016

Pharmacodynamics and Pharmacokinetics of Morphine After Cardiac Surgery in Children With and Without Down Syndrome.

Pediatr Crit Care Med 2016 10;17(10):930-938

1Intensive Care and Department of Pediatric Surgery, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, The Netherlands.2Division of Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.3Department of Anesthesia and Critical Care Medicine, Our Lady's Children's Hospital, Dublin, Ireland.4Department of Pharmacy, Academic Medical Center, Amsterdam, The Netherlands.5Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands.

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http://pdfs.journals.lww.com/pccmjournal/2016/10000/Pharmaco
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http://dx.doi.org/10.1097/PCC.0000000000000904DOI Listing
October 2016

The Effect of Weight and CYP3A5 Genotype on the Population Pharmacokinetics of Tacrolimus in Stable Paediatric Renal Transplant Recipients.

Clin Pharmacokinet 2016 09;55(9):1129-43

Department of Hospital Pharmacy-Clinical Pharmacology Unit, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s40262-016-0390-7DOI Listing
September 2016

Pharmacokinetic-guided dosing of factor VIII concentrate in a patient with haemophilia during renal transplantation.

BMJ Case Rep 2016 Sep 22;2016. Epub 2016 Sep 22.

Department of Paediatric Haematology, Erasmus University Medical Center-Sophia Childrens Hospital Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1136/bcr-2016-217069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051365PMC
September 2016

Prevalence and Implications of Abnormal Laboratory Results in Patients in the Terminal Phase of Life.

J Palliat Med 2016 08;19(8):822-9

5 Department of Hospital Pharmacy, Erasmus Medical Centre , Rotterdam, the Netherlands .

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http://dx.doi.org/10.1089/jpm.2015.0548DOI Listing
August 2016

A short-term high fat diet increases exposure to midazolam and omeprazole in healthy subjects.

Expert Opin Drug Metab Toxicol 2016 Jul 3;12(7):715-20. Epub 2016 Jun 3.

a Department of Internal Medicine, Academic Medical Center , University of Amsterdam , Amsterdam , The Netherlands.

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http://dx.doi.org/10.1080/17425255.2016.1192126DOI Listing
July 2016

Medication use during end-of-life care in a palliative care centre.

Int J Clin Pharm 2015 Oct 9;37(5):767-75. Epub 2015 Apr 9.

Pain Expertise Centre, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11096-015-0094-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594093PMC
October 2015

The "OPTI-CLOT" trial. A randomised controlled trial on periOperative PharmacokineTIc-guided dosing of CLOTting factor concentrate in haemophilia A.

Thromb Haemost 2015 Aug 11;114(3):639-44. Epub 2015 Jun 11.

M. H. Cnossen, MD, PhD, Department of Paediatric Haematology, Erasmus University Medical Centre, Sophia Children's Hospital Rotterdam, P. O. Box 2040, 3000 CA Rotterdam, the Netherlands, E-mail:

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http://dx.doi.org/10.1160/TH14-11-0925DOI Listing
August 2015

Short-term fasting alters cytochrome P450-mediated drug metabolism in humans.

Drug Metab Dispos 2015 Jun 20;43(6):819-28. Epub 2015 Mar 20.

Departments of Hospital Pharmacy (L.A.L., R.A.A.M.), Medicine (R.A., J.A.R.), Endocrinology and Metabolism (E.M.d.V., F.S.v.N., M.R.S., A.B.), and Medical Oncology (H.-J.K.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1124/dmd.114.062299DOI Listing
June 2015

Clinical evaluation of vancomycin dosage in pediatric oncology patients.

Pediatr Infect Dis J 2014 Jul;33(7):731-3

From the *Department of Clinical Pharmacy; †Department of Pediatric Infectious Diseases; and ‡Department of Pediatric Oncology, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/INF.0000000000000268DOI Listing
July 2014

Population pharmacokinetics of paracetamol across the human age-range from (pre)term neonates, infants, children to adults.

J Clin Pharmacol 2014 Jun 23;54(6):619-29. Epub 2014 Jan 23.

Division of Pharmacology, LACDR, Leiden University, Leiden, The Netherlands; Erasmus MC Sophia Children's Hospital, Intensive Care and Department of Paediatric Intensive Care, Rotterdam, The Netherlands.

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http://doi.wiley.com/10.1002/jcph.259
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http://dx.doi.org/10.1002/jcph.259DOI Listing
June 2014

Pharmacokinetic-pharmacodynamic modeling of the antihypertensive effect of eprosartan in Black and White hypertensive patients.

Clin Pharmacokinet 2013 Sep;52(9):793-803

Department of Clinical Pharmacy, Academic Medical Center, University of Amsterdam, Meibergdreef 9, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands.

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http://link.springer.com/10.1007/s40262-013-0073-6
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http://dx.doi.org/10.1007/s40262-013-0073-6DOI Listing
September 2013

Effect of hypothermia and extracorporeal life support on drug disposition in neonates.

Semin Fetal Neonatal Med 2013 Feb 15;18(1):23-7. Epub 2012 Nov 15.

Intensive Care and Department of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.siny.2012.10.002DOI Listing
February 2013

Intra-patient variability in tacrolimus trough concentrations and renal function decline in pediatric renal transplant recipients.

Pediatr Transplant 2012 Sep 13;16(6):613-8. Epub 2012 Jun 13.

Department of Pediatric Nephrology, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1399-3046.2012.01727.xDOI Listing
September 2012

Sample collection, biobanking, and analysis.

Handb Exp Pharmacol 2011 ;205:203-17

Department of Clinical Pharmacy, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/978-3-642-20195-0_10DOI Listing
February 2012

Ultrafast selective quantification of methotrexate in human plasma by high-throughput MALDI-isotope dilution mass spectrometry.

Bioanalysis 2011 Jun;3(12):1369-78

Laboratories of Neuro-Oncology & Clinical & Cancer Proteomics, Department of Neurology, University Medical Center Rotterdam (ErasmusMC), Dr. Molewaterplein 50, Room Ee-1981, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.4155/bio.11.113DOI Listing
June 2011

Acute liver failure after recommended doses of acetaminophen in patients with myopathies.

Crit Care Med 2011 Apr;39(4):678-82

Intensive Care and Department of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/CCM.0b013e318206cc8fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209512PMC
April 2011

Therapeutic drug monitoring for the individualization of docetaxel dosing: a randomized pharmacokinetic study.

Clin Cancer Res 2011 Jan 11;17(2):353-62. Epub 2011 Jan 11.

Department of Medical Oncology, Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1636DOI Listing
January 2011

High within-patient variability in the clearance of tacrolimus is a risk factor for poor long-term outcome after kidney transplantation.

Nephrol Dial Transplant 2010 Aug 26;25(8):2757-63. Epub 2010 Feb 26.

Department of Hospital Pharmacy, Molewaterplein 40, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gfq096DOI Listing
August 2010

Methotrexate-induced side effects are not due to differences in pharmacokinetics in children with Down syndrome and acute lymphoblastic leukemia.

Haematologica 2010 Jul 23;95(7):1106-13. Epub 2010 Apr 23.

Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands.

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http://dx.doi.org/10.3324/haematol.2009.019778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895034PMC
July 2010

Population pharmacokinetics of midazolam and its metabolites during venoarterial extracorporeal membrane oxygenation in neonates.

Clin Pharmacokinet 2010 Jun;49(6):407-19

Department of Hospital Pharmacy (Clinical Pharmacology Unit), Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.2165/11319970-000000000-00000DOI Listing
June 2010

Quantification of levetiracetam in plasma of neonates by ultra performance liquid chromatography-tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2010 Mar 29;878(7-8):675-81. Epub 2010 Jan 29.

Department of Hospital Pharmacy, Erasmus University Medical Center, 's-Gravendijkwal 230, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S157002321000059
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http://dx.doi.org/10.1016/j.jchromb.2010.01.037DOI Listing
March 2010

Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients.

J Pharmacokinet Pharmacodyn 2009 Dec 11;36(6):541-64. Epub 2009 Nov 11.

Department of Hospital Pharmacy, Erasmus University Medical Center, 's-Gravendijkwal 230, 3015CE, Rotterdam, The Netherlands.

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http://link.springer.com/10.1007/s10928-009-9136-6
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http://dx.doi.org/10.1007/s10928-009-9136-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784070PMC
December 2009

Limited sampling strategies drawn within 3 hours postdose poorly predict mycophenolic acid area-under-the-curve after enteric-coated mycophenolate sodium.

Ther Drug Monit 2009 Oct;31(5):585-91

Department of Hospital Pharmacy, Clinical Pharmacology Unit, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/FTD.0b013e3181b8679aDOI Listing
October 2009

Pharmacokinetic modelling of the plasma protein binding of mycophenolic acid in renal transplant recipients.

Clin Pharmacokinet 2009 ;48(7):463-76

Department of Hospital Pharmacy, Erasmus Medical Centre, 3000 CA Rotterdam, the Netherlands.

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http://dx.doi.org/10.2165/11312600-000000000-00000DOI Listing
September 2009

Limited sampling strategies for therapeutic drug monitoring of mycophenolate mofetil therapy in patients with autoimmune disease.

Ther Drug Monit 2009 Jun;31(3):382-90

Department of Hospital Pharmacy, Erasmus University Medical Center, Room L-056, PO Box 2040, Rotterdam 3000 CA, The Netherlands.

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http://dx.doi.org/10.1097/FTD.0b013e3181a23f1aDOI Listing
June 2009

Combination therapy of advanced invasive pulmonary aspergillosis in transiently neutropenic rats using human pharmacokinetic equivalent doses of voriconazole and anidulafungin.

Antimicrob Agents Chemother 2009 May 23;53(5):2005-13. Epub 2009 Feb 23.

Erasmus MC, University Medical Center Rotterdam, Department of Medical Microbiology and Infectious Diseases, s-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1128/AAC.01556-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681552PMC
May 2009

Pharmacokinetics and analgesic effects of intravenous propacetamol vs rectal paracetamol in children after major craniofacial surgery.

Paediatr Anaesth 2008 Jul 8;18(7):582-92. Epub 2008 May 8.

Department of Pediatric Surgery, Erasmus MC, Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1460-9592.2008.02619.xDOI Listing
July 2008

Caspofungin prolongs survival of transiently neutropenic rats with advanced-stage invasive pulmonary aspergillosis.

Antimicrob Agents Chemother 2008 Apr 14;52(4):1345-50. Epub 2008 Jan 14.

Erasmus MC, University Medical Center Rotterdam, Department of Medical Microbiology & Infectious Diseases, 's-Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1128/AAC.00536-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292535PMC
April 2008

Influence of ketoconazole on the fecal and urinary disposition of docetaxel.

Cancer Chemother Pharmacol 2007 Sep 26;60(4):569-79. Epub 2007 Jan 26.

Department of Medical Oncology, Erasmus MC - Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00280-006-0412-5DOI Listing
September 2007

Pharmacokinetics of aztreonam in healthy subjects and patients with cystic fibrosis and evaluation of dose-exposure relationships using monte carlo simulation.

Antimicrob Agents Chemother 2007 Sep 18;51(9):3049-55. Epub 2007 Jun 18.

Pediatric Pharmacology Research Unit, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 6018, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1128/AAC.01522-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043218PMC
September 2007

Irinotecan chemotherapy during valproic acid treatment: pharmacokinetic interaction and hepatotoxicity.

Cancer Biol Ther 2007 Sep 13;6(9):1368-74. Epub 2007 Jun 13.

Department of Medical Oncology, Erasmus MC University Medical Center-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.4161/cbt.6.9.4567DOI Listing
September 2007

Therapeutic drug monitoring of mycophenolic acid: does it improve patient outcome?

Expert Opin Drug Metab Toxicol 2007 Apr;3(2):251-61

Erasmus Medical Center, Department of Hospital Pharmacy, Clinical Pharmacology Unit, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1517/17425255.3.2.251DOI Listing
April 2007

Medicinal cannabis does not influence the clinical pharmacokinetics of irinotecan and docetaxel.

Oncologist 2007 Mar;12(3):291-300

Department of Medical Oncology, Erasmus MC University Medical Center Rotterdam - Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1634/theoncologist.12-3-291DOI Listing
March 2007

Alternative drug formulations of docetaxel: a review.

Anticancer Drugs 2007 Feb;18(2):95-103

Department of Medical Oncology, Erasmus MC, Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/CAD.0b013e3280113338DOI Listing
February 2007

Influence of high-dose ketoconazole on the pharmacokinetics of docetaxel.

Cancer Biol Ther 2006 Jul 22;5(7):833-9. Epub 2006 Jul 22.

Department of Medical Oncology, Daniel den Hoed Cancer Center, Erasmus MC, Rotterdam, the Netherlands.

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http://dx.doi.org/10.4161/cbt.5.7.2839DOI Listing
July 2006

Population pharmacokinetics and pharmacodynamics of nelfinavir and its active metabolite M8 in HIV-1-infected children.

Pediatr Infect Dis J 2006 Jun;25(6):538-43

Department of Pharmacy & Pharmacology, Slotervaart Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/01.inf.0000215242.70300.95DOI Listing
June 2006

Caspofungin: antifungal activity in vitro, pharmacokinetics, and effects on fungal load and animal survival in neutropenic rats with invasive pulmonary aspergillosis.

J Antimicrob Chemother 2006 Apr 7;57(4):732-40. Epub 2006 Feb 7.

Department of Medical Microbiology & Infectious Diseases, Erasmus MC, University Medical Center Rotterdam, The Netherlands.

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http://dx.doi.org/10.1093/jac/dkl015DOI Listing
April 2006

Individualization of mycophenolate mofetil dose in renal transplant recipients.

Expert Opin Pharmacother 2006 Mar;7(4):361-76

Department of Hospital Pharmacy, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1517/14656566.7.4.361DOI Listing
March 2006

Population pharmacokinetics of mycophenolic acid in renal transplant recipients.

Clin Pharmacokinet 2005 ;44(10):1083-96

Clinical Pharmacology Unit, Department of Hospital Pharmacy, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.2165/00003088-200544100-00006DOI Listing
January 2006

Estimation of the glomerular filtration rate in children: which algorithm should be used?

Pediatr Nephrol 2005 Dec 24;20(12):1769-75. Epub 2005 Aug 24.

Department of Hospital Pharmacy, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00467-005-2001-yDOI Listing
December 2005

Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2.

Am J Transplant 2005 May;5(5):987-94

Department of Internal Medicine, Renal Transplant Unit, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://doi.wiley.com/10.1046/j.1600-6143.2005.00779.x
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http://dx.doi.org/10.1046/j.1600-6143.2005.00779.xDOI Listing
May 2005

Mycophenolic acid in diabetic renal transplant recipients: pharmacokinetics and application of a limited sampling strategy.

Ther Drug Monit 2004 Dec;26(6):620-5

Department of Hospital Pharmacy, Clinical Pharmacology Unit, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/00007691-200412000-00006DOI Listing
December 2004

Pharmacogenetics in immunosuppressive therapy: the best thing since TDM?

Ther Drug Monit 2004 Aug;26(4):343-6

Department of Hospital Pharmacy, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/00007691-200408000-00001DOI Listing
August 2004

Bayesian pharmacokinetically guided dosing of paclitaxel in patients with non-small cell lung cancer.

Clin Cancer Res 2004 Apr;10(7):2237-44

Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute, Slotervaart Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1158/1078-0432.ccr-03-0060DOI Listing
April 2004