Romel Somwar

Romel Somwar

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Romel Somwar

Romel Somwar

Publications by authors named "Romel Somwar"

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Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers.

J Thorac Oncol 2019 May 1;14(5):802-815. Epub 2019 Mar 1.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.12.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486868PMC
May 2019

Integrative Genomic Analyses Identifies GGA2 as a Cooperative Driver of EGFR-Mediated Lung Tumorigenesis.

J Thorac Oncol 2019 Apr 19;14(4):656-671. Epub 2018 Dec 19.

Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada; Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440869PMC
April 2019

A blast from the past: on the brain.

Oncotarget 2019 Mar 1;10(18):1664-1666. Epub 2019 Mar 1.

Department of Pediatrics, Oregon Health Sciences University, Beaverton, OR, USA.

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http://dx.doi.org/10.18632/oncotarget.26752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422201PMC
March 2019

Spatiotemporal dynamics of triglyceride storage in unilocular adipocytes.

Mol Biol Cell 2014 Dec 8;25(25):4096-105. Epub 2014 Oct 8.

Divisions of Diabetes, Obesity, and Metabolism and Developmental and Reproductive Science, Beaverton, OR 97006

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http://dx.doi.org/10.1091/mbc.E14-06-1085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263452PMC
December 2014

Protein interaction discovery using parallel analysis of translated ORFs (PLATO).

Nat Biotechnol 2013 Apr 17;31(4):331-334. Epub 2013 Mar 17.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1038/nbt.2539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110636PMC
April 2013

Dosimetry of 18F-labeled tyrosine kinase inhibitor SKI-249380, a dasatinib-tracer for PET imaging.

Mol Imaging Biol 2012 Feb;14(1):25-31

Nuclear Medicine Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Room H-214B, Box 77, New York, NY 10065, USA.

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http://dx.doi.org/10.1007/s11307-010-0462-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113455PMC
February 2012

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines.

Proc Natl Acad Sci U S A 2011 Sep 19;108(39):16375-80. Epub 2011 Sep 19.

High Throughput Screening Core Facility, and Organic Synthesis Core Facility, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. or

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http://dx.doi.org/10.1073/pnas.1113554108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182729PMC
September 2011

Live-cell imaging demonstrates rapid cargo exchange between lipid droplets in adipocytes.

FEBS Lett 2011 Jun 12;585(12):1946-50. Epub 2011 May 12.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, United States.

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http://dx.doi.org/10.1016/j.febslet.2011.05.016DOI Listing
June 2011

Single-cell analysis of insulin-regulated fatty acid uptake in adipocytes.

Am J Physiol Endocrinol Metab 2010 Sep 22;299(3):E486-96. Epub 2010 Jun 22.

Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, 97006, USA.

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http://dx.doi.org/10.1152/ajpendo.00330.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944284PMC
September 2010

Identification and preliminary characterization of novel small molecules that inhibit growth of human lung adenocarcinoma cells.

J Biomol Screen 2009 Dec;14(10):1176-84

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://journals.sagepub.com/doi/10.1177/1087057109350919
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http://dx.doi.org/10.1177/1087057109350919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146390PMC
December 2009

Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas.

PLoS Med 2007 Oct;4(10):e294

Pao Laboratory, Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.0040294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001209PMC
October 2007

Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors.

Clin Cancer Res 2006 Nov;12(21):6494-501

Human Oncology and Pathogenesis Program, Thoracic Oncology Service, Varmus Lab, Department of Pathology, Memorial Sloan-Kettering Cancer Center, Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-1570DOI Listing
November 2006

Maturation of the regulation of GLUT4 activity by p38 MAPK during L6 cell myogenesis.

J Biol Chem 2003 May 11;278(20):17953-62. Epub 2003 Mar 11.

Programme in Cell Biology, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.

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http://dx.doi.org/10.1074/jbc.M211136200DOI Listing
May 2003

Activation of the glucose transporter GLUT4 by insulin.

Biochem Cell Biol 2002 ;80(5):569-78

Programme in Cell Biology, Hospital for Sick Children, University of Toronto, ON, Canada.

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http://dx.doi.org/10.1139/o02-156DOI Listing
April 2003

Sustained exposure of L6 myotubes to high glucose and insulin decreases insulin-stimulated GLUT4 translocation but upregulates GLUT4 activity.

Diabetes 2002 Jul;51(7):2090-8

Programme in Cell Biology, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8.

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http://dx.doi.org/10.2337/diabetes.51.7.2090DOI Listing
July 2002