Romano Danesi

Romano Danesi

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Romano Danesi

Romano Danesi

Publications by authors named "Romano Danesi"

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Management of adverse events associated with tyrosine kinase inhibitors: Improving outcomes for patients with hepatocellular carcinoma.

Cancer Treat Rev 2019 May 15;77:20-28. Epub 2019 May 15.

Department of Hepatology, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Université Lyon 1, 103 Grande rue de la Croix Rousse, Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2019.05.004DOI Listing
May 2019

The increase in activating EGFR mutation in plasma is an early biomarker to monitor response to osimertinib: a case report.

BMC Cancer 2019 Apr 30;19(1):410. Epub 2019 Apr 30.

Unit of Respiratory Medicine, Department of Critical Area and Surgical, Medical and Molecular Pathology, University Hospital of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1186/s12885-019-5604-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492432PMC
April 2019

Drug-drug interactions in breast cancer patients treated with CDK4/6 inhibitors.

Cancer Treat Rev 2019 Mar 19;74:21-28. Epub 2019 Jan 19.

Unit of Clinical Pharmacology and Pharmacogenetics, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1016/j.ctrv.2019.01.006DOI Listing
March 2019

The emerging role of liquid biopsy in diagnosis, prognosis and treatment monitoring of pancreatic cancer.

Pharmacogenomics 2019 Jan 6;20(1):49-68. Epub 2018 Dec 6.

Unit of Clinical Pharmacology & Pharmacogenetics, Department of Clinical & Experimental Medicine, University of Pisa, Italy.

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http://dx.doi.org/10.2217/pgs-2018-0149DOI Listing
January 2019

Rebuttal letter: Different underlying mechanism might explain the absence of a significant difference in AUC of linezolid for different ABCB1 genotypes.

Ther Drug Monit 2019 Jan 9. Epub 2019 Jan 9.

Department of Medical Sciences, University of Turin Laboratory of Clinical Pharmacology and Pharmacogenetics,Turin, Italy.

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http://dx.doi.org/10.1097/FTD.0000000000000596DOI Listing
January 2019

Radiomics and liquid biopsy in oncology: the holons of systems medicine.

Insights Imaging 2018 Dec 14;9(6):915-924. Epub 2018 Nov 14.

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://link.springer.com/10.1007/s13244-018-0657-7
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http://dx.doi.org/10.1007/s13244-018-0657-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269342PMC
December 2018

The amount of activating EGFR mutations in circulating cell-free DNA is a marker to monitor osimertinib response.

Br J Cancer 2018 Nov 6;119(10):1252-1258. Epub 2018 Nov 6.

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://www.nature.com/articles/s41416-018-0238-z
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http://dx.doi.org/10.1038/s41416-018-0238-zDOI Listing
November 2018

A Common mdr1 Gene Polymorphism is Associated With Changes in Linezolid Clearance.

Ther Drug Monit 2018 10;40(5):602-609

Department of Medical Sciences, University of Turin-ASL "Città di Torino," Laboratory of Clinical Pharmacology and Pharmacogenetics Padiglione Q, Amedeo di Savoia Hospital, Turin, Italy.

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http://dx.doi.org/10.1097/FTD.0000000000000536DOI Listing
October 2018

The use of intravenous versus subcutaneous monoclonal antibodies in the treatment of severe asthma: a review.

Respir Res 2018 Aug 16;19(1):154. Epub 2018 Aug 16.

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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https://respiratory-research.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s12931-018-0859-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097430PMC
August 2018

Clinical pharmacology of intravitreal anti-VEGF drugs.

Eye (Lond) 2018 06 5;32(6):1010-1020. Epub 2018 Feb 5.

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1038/s41433-018-0021-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997665PMC
June 2018

EGFR-TKIs in non-small-cell lung cancer: focus on clinical pharmacology and mechanisms of resistance.

Pharmacogenomics 2018 06 22;19(8):727-740. Epub 2018 May 22.

Clinical Pharmacology & Pharmacogenetics Unit, Department of Clinical & Experimental Medicine, University of Pisa, Italy.

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http://dx.doi.org/10.2217/pgs-2018-0038DOI Listing
June 2018

Concise Review: Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer: The Role of Cancer Stem Cells.

Stem Cells 2018 05 5;36(5):633-640. Epub 2018 Feb 5.

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1002/stem.2787DOI Listing
May 2018

Pharmacogenetics of androgen signaling in prostate cancer: Focus on castration resistance and predictive biomarkers of response to treatment.

Crit Rev Oncol Hematol 2018 May 6;125:51-59. Epub 2018 Mar 6.

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2018.03.002DOI Listing
May 2018

Pharmacogenetics and Metabolism from Science to Implementation in Clinical Practice: The Example of Dihydropyrimidine Dehydrogenase.

Curr Pharm Des 2017 ;23(14):2028-2034

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.2174/1381612823666170125155530DOI Listing
April 2018

Individualized dosing with axitinib: rationale and practical guidance.

Future Oncol 2018 Apr 21;14(9):861-875. Epub 2017 Dec 21.

Medical Oncology Department, University of Lyon, Centre Léon Bérard, Lyon, France.

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http://dx.doi.org/10.2217/fon-2017-0455DOI Listing
April 2018

Phosphorylation of AKT and ERK1/2 and mutations of PIK3CA and PTEN are predictive of breast cancer cell sensitivity to everolimus in vitro.

Cancer Chemother Pharmacol 2018 04 23;81(4):745-754. Epub 2018 Feb 23.

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, 55, Via Roma, 56126, Pisa, Italy.

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http://dx.doi.org/10.1007/s00280-018-3543-6DOI Listing
April 2018

Management of Adverse Events Associated with Cabozantinib Therapy in Renal Cell Carcinoma.

Oncologist 2018 Mar 16;23(3):306-315. Epub 2017 Nov 16.

Clinical Pharmacology and Pharmacogenetic Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1634/theoncologist.2017-0335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905684PMC
March 2018

Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment.

Stem Cells Transl Med 2018 Mar 8;7(3):305-314. Epub 2018 Feb 8.

Unit of Clinical Pharmacology and Pharmacogenetics, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1002/sctm.17-0175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827745PMC
March 2018

Implications of KRAS mutations in acquired resistance to treatment in NSCLC.

Oncotarget 2018 01 21;9(5):6630-6643. Epub 2017 Dec 21.

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.18632/oncotarget.23553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814239PMC
January 2018

Detection of ALK and KRAS Mutations in Circulating Tumor DNA of Patients With Advanced ALK-Positive NSCLC With Disease Progression During Crizotinib Treatment.

Clin Lung Cancer 2017 11 18;18(6):692-697. Epub 2017 May 18.

Clinical Pharmacology and Pharmacogenetic Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1016/j.cllc.2017.04.013DOI Listing
November 2017

Early changes in plasma DNA levels of mutant KRAS as a sensitive marker of response to chemotherapy in pancreatic cancer.

Sci Rep 2017 08 11;7(1):7931. Epub 2017 Aug 11.

Unit of Clinical Pharmacology and Pharmacogenetics, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1038/s41598-017-08297-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554237PMC
August 2017

Sunitinib in Metastatic Renal Cell Carcinoma: The Pharmacological Basis of the Alternative 2/1 Schedule.

Front Pharmacol 2017 7;8:523. Epub 2017 Aug 7.

Department of Clinical and Experimental Medicine, University of PisaPisa, Italy.

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http://dx.doi.org/10.3389/fphar.2017.00523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545583PMC
August 2017

Should CYP2D6 be genotyped when treating with tamoxifen?

Pharmacogenomics 2017 Jun 8;18(8):755-756. Epub 2017 Jun 8.

Clinical Pharmacology & Pharmacogenetics Unit, Department of Clinical & Experimental Medicine, University of Pisa, Italy.

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http://dx.doi.org/10.2217/pgs-2017-0065DOI Listing
June 2017

Protein kinase inhibitors for the treatment of advanced and progressive radiorefractory thyroid tumors: From the clinical trials to the real life.

Best Pract Res Clin Endocrinol Metab 2017 06 15;31(3):319-334. Epub 2017 Jun 15.

Unit of Endocrinology, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Via Paradisa 2, 56124 Pisa, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1521690X173007
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http://dx.doi.org/10.1016/j.beem.2017.06.001DOI Listing
June 2017

The Language of Biosimilars: Clarification, Definitions, and Regulatory Aspects.

Drugs 2017 Apr;77(6):671-677

Pfizer Inc, 235 East 42nd Street, New York, NY, 10017-5755, USA.

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http://dx.doi.org/10.1007/s40265-017-0717-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375962PMC
April 2017

Determinants of bone specific metastasis in prostate cancer.

Crit Rev Oncol Hematol 2017 Apr 16;112:59-66. Epub 2017 Feb 16.

Medical Oncology Department, Campus Bio-Medico University, Via Alvaro del Portillo 200, 00128 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2017.02.013DOI Listing
April 2017

The role of drug-drug interactions in prostate cancer treatment: Focus on abiraterone acetate/prednisone and enzalutamide.

Cancer Treat Rev 2017 Apr 9;55:71-82. Epub 2017 Mar 9.

Department of Clinical and Experimental Medicine, University of Pisa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2017.03.001DOI Listing
April 2017

Unusual gastrointestinal and cutaneous toxicities by bleomycin, etoposide, and cisplatin: a case report with pharmacogenetic analysis to personalize treatment.

EPMA J 2017 Mar 7;8(1):69-73. Epub 2017 Mar 7.

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, 55, Via Roma, 56126 Pisa, Italy.

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http://dx.doi.org/10.1007/s13167-017-0080-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471801PMC
March 2017

Topoisomerase 1 Promoter Variants and Benefit from Irinotecan in Metastatic Colorectal Cancer Patients.

Oncology 2016 31;91(5):283-288. Epub 2016 Aug 31.

Unit of Clinical Pharmacology and Pharmacogenetics, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1159/000448004DOI Listing
January 2017

Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins.

Int J Mol Sci 2017 Jan 6;18(1). Epub 2017 Jan 6.

Clinical Pharmacology and Pharmacogenetic Unit, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126 Pisa, Italy.

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http://dx.doi.org/10.3390/ijms18010104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297738PMC
January 2017

ATP-binding cassette transmembrane transporters and their epigenetic control in cancer: an overview.

Expert Opin Drug Metab Toxicol 2016 Dec 3;12(12):1419-1432. Epub 2016 Aug 3.

a Section of Pharmacology, Department of Clinical and Experimental Medicine , University of Pisa , Pisa , Italy.

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http://dx.doi.org/10.1080/17425255.2016.1215423DOI Listing
December 2016

Should CYP2D6 be genotyped when treating with tamoxifen?

Pharmacogenomics 2016 12 24;17(18):1967-1969. Epub 2016 Nov 24.

Clinical Pharmacology & Pharmacogenetics Unit, Department of Clinical & Experimental Medicine, University of Pisa, 55 Via Roma, 56126 Pisa, Italy.

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http://dx.doi.org/10.2217/pgs-2016-0162DOI Listing
December 2016

Uncommon dihydropyrimidine dehydrogenase mutations and toxicity by fluoropyrimidines: a lethal case with a new variant.

Pharmacogenomics 2016 14;17(1):5-9. Epub 2015 Dec 14.

Departmental Unit of Medical Oncology, IRCCS Fondazione Maugeri, 4, Via Salvatore Maugeri, I-27100 Pavia, Italy.

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http://dx.doi.org/10.2217/pgs.15.146DOI Listing
September 2016

Recent advances in epigenomics in NSCLC: real-time detection and therapeutic implications.

Epigenomics 2016 08 1;8(8):1151-67. Epub 2016 Aug 1.

Department of Clinical & Experimental Medicine, University of Pisa, Via Roma 55, 56126 Pisa, Italy.

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http://dx.doi.org/10.2217/epi.16.10DOI Listing
August 2016

Pegfilgrastim for the prevention of chemotherapy-induced febrile neutropenia in patients with solid tumors.

Expert Opin Biol Ther 2015 21;15(12):1799-817. Epub 2015 Oct 21.

a Department of Medical Oncology, U.O. Oncologia Medica 2 , IRCCS AOU San Martino - IST , 16132 Genoa , Italy.

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http://dx.doi.org/10.1517/14712598.2015.1101063DOI Listing
July 2016

Incidence and relative risk of adverse events of special interest in patients with castration resistant prostate cancer treated with CYP-17 inhibitors: A meta-analysis of published trials.

Crit Rev Oncol Hematol 2016 May 27;101:12-20. Epub 2016 Feb 27.

Unit of molecular therapy and pharmacogenomic, AO Azienda Istituti Ospitalieri di Cremona, Viale Concordia 1, 26100 Cremona, Italy; Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129 Trieste, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2016.02.013DOI Listing
May 2016

Methods: for studying pharmacogenetic profiles of combination chemotherapeutic drugs.

Expert Opin Drug Metab Toxicol 2015 3;11(8):1253-67. Epub 2015 Jun 3.

University of Pisa, Department of Clinical and Experimental Medicine, Via Roma 55, 56126 Pisa , Italy +39 050 2218755 ; +39 050 2218758 ;

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http://dx.doi.org/10.1517/17425255.2015.1053460DOI Listing
March 2016

Mathematical modeling of drug resistance due to KRAS mutation in colorectal cancer.

J Theor Biol 2016 Jan 6;389:263-73. Epub 2015 Nov 6.

Clinical Pharmacology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.

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http://dx.doi.org/10.1016/j.jtbi.2015.10.019DOI Listing
January 2016

Pathophysiology and pharmacological targets of VEGF in diabetic macular edema.

Pharmacol Res 2016 Jan 1;103:149-57. Epub 2015 Dec 1.

Department of Clinical and Experimental Medicine, University of Pisa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2015.11.003DOI Listing
January 2016

Refining sorafenib therapy: lessons from clinical practice.

Future Oncol 2015 31;11(3):449-65. Epub 2014 Oct 31.

Division of Internal Medicine, Department of Medical & Surgical Sciences, University of Bologna, S Orsola-Malpighi Hospital, Bologna, Italy.

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http://dx.doi.org/10.2217/fon.14.261DOI Listing
November 2015

Circulating DNA in diagnosis and monitoring EGFR gene mutations in advanced non-small cell lung cancer.

Transl Lung Cancer Res 2015 Oct;4(5):584-97

1 Medical Oncology Unit, University Hospital of Parma, Parma, Italy ; 2 Department of Clinical and Experimental Medicine, Clinical Pharmacology Unit, University of Pisa, Italy.

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http://dx.doi.org/10.3978/j.issn.2218-6751.2015.08.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630520PMC
October 2015

Comment on "High expression of CD39/ENTPD1 in malignant epithelial cells of human rectal adenocarcinoma".

Tumour Biol 2015 Sep 17;36(10):7397-8. Epub 2015 Sep 17.

Division of Pharmacology and Chemotherapy, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126, Pisa, Italy.

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http://dx.doi.org/10.1007/s13277-015-4030-xDOI Listing
September 2015

Pharmacogenetics of BCR/ABL Inhibitors in Chronic Myeloid Leukemia.

Int J Mol Sci 2015 Sep 21;16(9):22811-29. Epub 2015 Sep 21.

Department of Clinical and Experimental Medicine, Section of Pharmacology, University of Pisa, Via Roma 55, 56126 Pisa, Italy.

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http://dx.doi.org/10.3390/ijms160922811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613337PMC
September 2015

Lessons from the first ecancer symposium on angiogenesis in gastric cancer.

Ecancermedicalscience 2015 21;9:553. Epub 2015 Jul 21.

European Institute of Oncology, Milan 20146, Italy; University of Milan, Italy; University of Glasgow, G12 8QQ, United Kingdom; University of Wales, Cardiff, South Glam CF10 3NS, United Kingdom; Founding editor of ecancer.org.

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http://dx.doi.org/10.3332/ecancer.2015.553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531128PMC
August 2015

Investigational therapies targeting signal transducer and activator of transcription 3 for the treatment of cancer.

Expert Opin Investig Drugs 2015 Jun 7;24(6):809-24. Epub 2015 Mar 7.

Polytechnic University of the Marche Region, Medical Oncology, AOU Ospedali Riuniti , via Conca 71, 60126 Ancona , Italy +39 0715964263 ; +39 0715964269 ;

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http://www.tandfonline.com/doi/full/10.1517/13543784.2015.10
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http://dx.doi.org/10.1517/13543784.2015.1020370DOI Listing
June 2015

Steroids in prostate cancer: the jury is still out... and even more confused.

Eur Urol 2015 Apr 20;67(4):680-1. Epub 2014 Nov 20.

Clinical Pharmacology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1016/j.eururo.2014.11.002DOI Listing
April 2015

EPMA position paper in cancer: current overview and future perspectives.

EPMA J 2015 15;6(1). Epub 2015 Apr 15.

Department of Neurology, University of Tennessee Center for Health Science, Memphis, USA.

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http://dx.doi.org/10.1186/s13167-015-0030-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407842PMC
April 2015

Genetic variation: effect on prostate cancer.

Biochim Biophys Acta 2014 Dec 6;1846(2):446-56. Epub 2014 Sep 6.

Department of Clinical and Experimental Medicine, University of Pisa, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S0304419X140008
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http://dx.doi.org/10.1016/j.bbcan.2014.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260983PMC
December 2014

Effects of amiodarone, thyroid hormones and CYP2C9 and VKORC1 polymorphisms on warfarin metabolism: a review of the literature.

Endocr Pract 2013 Nov-Dec;19(6):1043-9

Department of Clinical and Experimental Medicine, Section of Endocrinology, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.4158/EP13093.RADOI Listing
July 2014

Different recommendations for daptomycin dosing over time in patients with severe infections.

Clin Infect Dis 2014 Jun 11;58(12):1788-9. Epub 2014 Apr 11.

Department of Clinical and Experimental Medicine, University of Pisa.

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http://dx.doi.org/10.1093/cid/ciu230DOI Listing
June 2014

Molecular analysis of cell-free circulating DNA for the diagnosis of somatic mutations associated with resistance to tyrosine kinase inhibitors in non-small-cell lung cancer.

Expert Rev Mol Diagn 2014 May 11;14(4):453-68. Epub 2014 Apr 11.

Department of Clinical and Experimental Medicine, Clinical Pharmacology Unit, Pisa University, Pisa, Italy.

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http://dx.doi.org/10.1586/14737159.2014.908120DOI Listing
May 2014

CLM3, a multitarget tyrosine kinase inhibitor with antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo.

J Clin Endocrinol Metab 2014 Apr 1;99(4):E572-81. Epub 2014 Jan 1.

Departments of Clinical and Experimental Medicine (A.A., G.B., P.F., S.M.F., C.M., A.F., T.D.D., R.D.), Pharmacy (C.L.M., S.S., F.D.S.), Translational Research and New Technologies in Medicine and Surgery (A.C., S.P.), and Surgical, Medical, Molecular Pathology, and Critical Area (G.M., C.S., G.F., P.M.), University of Pisa, 56126 Pisa, Italy; and Istituto Toscano Tumori (G.B.), 50139 Florence, Italy.

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http://dx.doi.org/10.1210/jc.2013-2321DOI Listing
April 2014

Breast lymphomas around breast implants.

Ann Surg 2014 Jan;259(1):e4

Plastic and Reconstructive Surgery Unit Hospital of Pisa, Italy Division of Pharmacology Department of Internal Medicine University Hospital of Pisa, Italy Plastic and Reconstructive Surgery Unit Hospital of Pisa, Italy Division of Pharmacology Department of Internal Medicine University Hospital of Pisa, Italy.

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http://dx.doi.org/10.1097/SLA.0b013e3182a59875DOI Listing
January 2014

Oral and intravenously administered mTOR inhibitors for metastatic renal cell carcinoma: pharmacokinetic considerations and clinical implications.

Cancer Treat Rev 2013 Nov 30;39(7):784-92. Epub 2013 Jan 30.

Department of Clinical and Experimental Medicine, University of Pisa, Italy.

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http://dx.doi.org/10.1016/j.ctrv.2012.12.012DOI Listing
November 2013

Population pharmacokinetics of daptomycin in patients affected by severe Gram-positive infections.

Int J Antimicrob Agents 2013 Sep 25;42(3):250-5. Epub 2013 Jul 25.

Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126 Pisa, Italy.

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http://dx.doi.org/10.1016/j.ijantimicag.2013.06.006DOI Listing
September 2013

DPYD IVS14+1G>A and 2846A>T genotyping for the prediction of severe fluoropyrimidine-related toxicity: a meta-analysis.

Pharmacogenomics 2013 Aug;14(11):1255-72

Dipartimento di Scienze del Farmaco & Centro di Ricerca Interdipartimentale di Farmacogenetica e Farmacogenomica-CRIFF, Università del Piemonte Orientale "A. Avogadro", Largo Donegani 2, 28100 Novara, Italy.

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http://dx.doi.org/10.2217/pgs.13.116DOI Listing
August 2013

The pharmacological bases of the antiangiogenic activity of paclitaxel.

Angiogenesis 2013 Jul 7;16(3):481-92. Epub 2013 Feb 7.

Division of Pharmacology, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126 Pisa, Italy.

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http://dx.doi.org/10.1007/s10456-013-9334-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682088PMC
July 2013

Clinical pharmacokinetics of antibacterials in cerebrospinal fluid.

Clin Pharmacokinet 2013 Jul;52(7):511-42

Division of Pharmacology, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, 56126, Pisa, Italy.

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http://dx.doi.org/10.1007/s40262-013-0062-9DOI Listing
July 2013

Author's reply: To PMID 22443211.

Expert Opin Ther Targets 2013 Apr;17(4):474-5

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April 2013