Publications by authors named "Romain Wolf"

17Publications

Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors.

ACS Med Chem Lett 2017 Sep 25;8(9):975-980. Epub 2017 Aug 25.

Global Discovery Chemistry, PK Sciences, Chemical Biology and Therapeutics, and Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002 Basel, Switzerland.

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September 2017

Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors.

ACS Med Chem Lett 2016 Aug 2;7(8):762-7. Epub 2016 Jun 2.

Global Discovery Chemistry, Center for Proteomic Chemistry, Metabolism and Pharmacokinetics, Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research , Novartis Campus, CH-4002 Basel, Switzerland.

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August 2016

Extracting ligands from receptors by reversed targeted molecular dynamics.

Authors:
Romain M Wolf

J Comput Aided Mol Des 2015 Nov 5;29(11):1025-34. Epub 2015 Aug 5.

Novartis Institutes for Biomedical Research, NIBR, Novartis Pharma AG, Basel, Switzerland.

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November 2015

MM/GBSA binding energy prediction on the PDBbind data set: successes, failures, and directions for further improvement.

J Chem Inf Model 2013 Jan 27;53(1):201-9. Epub 2012 Dec 27.

Novartis Institutes for Biomedical Research, Novartis Pharma AG, Forum 1, Novartis Campus, CH 4056 Basel, Switzerland.

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January 2013

Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183).

J Biol Chem 2012 Oct 8;287(42):35470-83. Epub 2012 Aug 8.

Laboratory for Molecular Pharmacology, Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark.

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October 2012

Improved model building and assessment of the Calcium-sensing receptor transmembrane domain.

Proteins 2008 Apr;71(1):215-26

Department of Molecular Biology (TPC6), The Scripps Research Institute, La Jolla, California 92037, USA.

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April 2008

Receptors for protons or lipid messengers or both?

J Recept Signal Transduct Res 2006 ;26(5-6):599-610

Novartis Institutes for Biomedical Research, Basel, Switzerland.

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March 2007

Development and testing of a general amber force field.

J Comput Chem 2004 Jul;25(9):1157-74

Encysive Pharmaceuticals Inc., 7000 Fannin, Houston, Texas 77030, USA.

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July 2004

Homology modeling of the transmembrane domain of the human calcium sensing receptor and localization of an allosteric binding site.

J Biol Chem 2004 Feb 2;279(8):7254-63. Epub 2003 Dec 2.

Department of Biology, Syracuse University, Syracuse, New York 13244, USA.

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February 2004

Proton-sensing G-protein-coupled receptors.

Nature 2003 Sep;425(6953):93-8

Novartis Institutes for Biomedical Research, CH-4002 Basel, Switzerland.

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September 2003

Simulation of the different biological activities of diethylstilbestrol (DES) on estrogen receptor alpha and estrogen-related receptor gamma.

Biopolymers 2003 Jan;68(1):130-8

Novartis/UMDNJ Predoctoral Fellowship Program, Graduate School of Biomedical Sciences, University of Medicine, 625 Hoes Lane, Piscataway, NJ 08855, USA.

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January 2003

Dual Recognition of Double-Stranded DNA by 2'-Aminoethoxy-Modified Oligonucleotides.

Angew Chem Int Ed Engl 1998 May;37(9):1288-1291

Novartis Horsham Research Centre, Wimblehurst road, Horsham, West Sussex, RH12 4AB (UK), Fax: (+44) 1403-32 33 07.

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May 1998