Rolf Stahel

Rolf Stahel

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Rolf Stahel

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Underweight and weight loss are predictors of poor outcome in patients with brain metastasis.

J Neurooncol 2019 Sep 30. Epub 2019 Sep 30.

Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Frauenklinikstrasse 26, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s11060-019-03300-1DOI Listing
September 2019

Intracavitary cisplatin-fibrin chemotherapy after surgery for malignant pleural mesothelioma: A phase I trial.

J Thorac Cardiovasc Surg 2019 Aug 22. Epub 2019 Aug 22.

Department of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.jtcvs.2019.07.073DOI Listing
August 2019

Diagnostic value of F-fluordesoxyglucose positron emission tomography for patients with brain metastasis from unknown primary site.

Eur J Cancer 2018 06 17;96:64-72. Epub 2018 Apr 17.

Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Frauenklinikstrasse 26, CH-8091, Zurich, Switzerland; Neuro-oncology, Department of Neurosurgery, University Hospital Lille, Salengro Hospital, Rue Emile Laine, FR-59037, Lille, France; Neurology, Department of Medical Oncology, Oscar Lambret Center, FR-59020, Lille, France; Inserm U-1192, Villeneuve d'Ascq, France.

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http://dx.doi.org/10.1016/j.ejca.2018.03.010DOI Listing
June 2018

Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression.

Front Oncol 2018 23;8:40. Epub 2018 Feb 23.

Laboratory of Molecular Oncology, Division of Thoracic Surgery, University Hospital Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.3389/fonc.2018.00040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829086PMC
February 2018

PD-1 blockade in advanced NSCLC: A focus on pembrolizumab.

Cancer Treat Rev 2018 Jan 23;62:39-49. Epub 2017 Oct 23.

Department of Oncology, University Hospital Zürich, Rämistrasse 100, 8091 Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2017.10.002DOI Listing
January 2018

A Novel BRCA1-Associated Protein-1 Isoform Affects Response of Mesothelioma Cells to Drugs Impairing BRCA1-Mediated DNA Repair.

J Thorac Oncol 2017 08 4;12(8):1309-1319. Epub 2017 Apr 4.

Laboratory of Molecular Oncology, Division of Thoracic Surgery, University Hospital Zürich, Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2017.03.023DOI Listing
August 2017

Safeguarding the future of independent, academic clinical cancer research in Europe for the benefit of patients.

ESMO Open 2017 3;2(3):e000187. Epub 2017 Aug 3.

European Society for Medical Oncology (ESMO), Clinic of Oncology,University Hospital, Zürich, Zurich, Switzerland.

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http://dx.doi.org/10.1136/esmoopen-2017-000187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634488PMC
August 2017

Propensity matched comparison of extrapleural pneumonectomy and pleurectomy/decortication for mesothelioma patients.

Interact Cardiovasc Thorac Surg 2017 05;24(5):740-746

Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1093/icvts/ivw422DOI Listing
May 2017

Prognostic and predictive value of loss of nuclear RAD51 immunoreactivity in resected non-small cell lung cancer patients.

Lung Cancer 2017 03 18;105:31-38. Epub 2017 Jan 18.

Department of Medical Oncology and Hematology, Cantonal Hospital, CH-9007 St. Gallen, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.01.009DOI Listing
March 2017

Toxicity of concurrent stereotactic radiotherapy and targeted therapy or immunotherapy: A systematic review.

Cancer Treat Rev 2017 Feb 19;53:25-37. Epub 2016 Dec 19.

Department of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.ctrv.2016.11.013DOI Listing
February 2017

Relapse pattern and second-line treatment following multimodality treatment for malignant pleural mesothelioma.

Eur J Cardiothorac Surg 2016 May 20;49(5):1516-23. Epub 2015 Nov 20.

Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland

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http://dx.doi.org/10.1093/ejcts/ezv398DOI Listing
May 2016

Diagnostic accuracy of sequential co-registered PET+MR in comparison to PET/CT in local thoracic staging of malignant pleural mesothelioma.

Lung Cancer 2016 Apr 28;94:40-5. Epub 2016 Jan 28.

Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.01.017DOI Listing
April 2016

Hemithoracic radiotherapy for mesothelioma: lack of benefit or lack of statistical power? - Authors' reply.

Lancet Oncol 2016 Feb;17(2):e44-e45

Department of Oncology, University Hospital, CH-8091 Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)00036-XDOI Listing
February 2016

A New Prognostic Score Supporting Treatment Allocation for Multimodality Therapy for Malignant Pleural Mesothelioma: A Review of 12 Years' Experience.

J Thorac Oncol 2015 Nov;10(11):1634-41

*Division of Thoracic Surgery, †Department of Diagnostic Radiology, University Hospital Zurich, Zurich, Switzerland; ‡Department of Biostatistics, Epidemiology, Biostatistics and Prevention Unit, University Zurich, Zurich, Switzerland; §Division of Thoracic Surgery, Medical University Vienna, Vienna, Austria; and ‖Laboratory of Molecular Oncology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/JTO.0000000000000661DOI Listing
November 2015

Use of computed tomography and positron emission tomography/computed tomography for staging of local extent in patients with malignant pleural mesothelioma.

J Comput Assist Tomogr 2015 Mar-Apr;39(2):160-5

From the *Institute of Diagnostic and Interventional Radiology, †Division of Thoracic Surgery, ‡Clinic of Nuclear Medicine, and §Clinic of Oncology, University Hospital of Zurich, Zurich, Switzerland.

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http://pdfs.journals.lww.com/jcat/2015/03000/Use_of_Computed
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http://dx.doi.org/10.1097/RCT.0000000000000174DOI Listing
May 2015

Prevalence of BRCA-1 associated protein 1 germline mutation in sporadic malignant pleural mesothelioma cases.

Lung Cancer 2015 Jan 6;87(1):77-9. Epub 2014 Nov 6.

Laboratory of Molecular Oncology, Clinic of Oncology, University Hospital of Zürich, Häldeliweg 4, 8044 Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2014.10.017DOI Listing
January 2015

Lungscape: resected non-small-cell lung cancer outcome by clinical and pathological parameters.

J Thorac Oncol 2014 Nov;9(11):1675-84

*Centre Hospitalier Universitaire de Vaud, Lausanne, Switzerland; †Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland; ‡Frontier Science Foundation-Hellas & University of Athens, Athens, Greece; §Aberdeen Royal Infirmary, Aberdeen, United Kingdom; ‖Institute for Pathology, University Hospital Basel, Basel, Switzerland; ¶Department of Oncology, University Hospital, Aarhus, Denmark; #Department of Medical Oncology, St. James's Hospital, Dublin, Ireland; **Medical University of Gdansk, Gdansk, Poland; ††University Hospital KU Leuven, Leuven, Belgium; ‡‡Vall d'Hebron University Hospital, Barcelona, Spain; §§Center of Predictive Molecular Medicine, University Foundation, Chieti, Italy; ‖‖Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China; ¶¶VU University Medical Center, Amsterdam, Netherlands; ##Maastricht University Medical Centre, Maastricht, Netherlands; ***Manchester University and The Christie National Health Services Foundation Trust, Manchester, United Kingdom; †††Netherlands Cancer Institute, Amsterdam, Netherlands; ‡‡‡Department of Medicine, University of Valencia and Department of Medical Oncology, General University Hospital of Valencia, Valencia, Spain; §§§Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain; and ‖‖‖Clinic of Oncology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/JTO.0000000000000320DOI Listing
November 2014

Prevalence and clinical outcomes for patients with ALK-positive resected stage I to III adenocarcinoma: results from the European Thoracic Oncology Platform Lungscape Project.

J Clin Oncol 2014 Sep 28;32(25):2780-7. Epub 2014 Jul 28.

Fiona H. Blackhall and Daisuke Nonaka, Manchester University and The Christie National Health Services Foundation Trust, Manchester; Keith M. Kerr, Aberdeen University Medical School, Aberdeen Royal Infirmary, Aberdeen, United Kingdom; Solange Peters and Igor Letovanec, Centre Hospitalier Universitaire Vaudois, Lausanne; Lukas Bubendorf and Spasenija Savic, Institute for Pathology, University Hospital Basel, Basel; Alex Soltermann and Rolf A. Stahel, University Hospital Zurich, Zurich, Switzerland; Urania Dafni, Frontier Science Foundation-Hellas and University of Athens, Athens, Greece; Henrik Hager, University Hospital, Aarhus, Denmark; Kenneth J. O'Byrne, St James's Hospital, Dublin, Ireland; Christoph Dooms, University Hospital KU Leuven, Leuven, Belgium; Aleksandra Sejda, Medical University of Gdansk, Gdansk, Poland; Javier Hernández-Losa, Vall d'Hebron University Hospital, Barcelona; Miguel Martorell, Universitat de Valencia and Hospital General Universitario de Valencia, Valencia; Rafael Rosell, Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain; Antonio Marchetti, Center of Predictive Molecular Medicine, University Foundation, Chieti, Italy; Qiang Tan, Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China; Erik Thunnissen, VU University Medical Clinic Center; Jeroen de Jong, Netherlands Cancer Institute, Amsterdam; Ernst-Jan M. Speel, Maastricht University Medical Centre, Maastricht, the Netherlands; and Richard Cheney, Roswell Park Cancer Institute, Buffalo, NY.

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http://dx.doi.org/10.1200/JCO.2013.54.5921DOI Listing
September 2014

Determinants of outcome of solitary fibrous tumors of the pleura: an observational cohort study.

BMC Pulm Med 2014 Aug 12;14:138. Epub 2014 Aug 12.

Division of Pulmonology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1186/1471-2466-14-138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134113PMC
August 2014

GAS5 long non-coding RNA in malignant pleural mesothelioma.

Mol Cancer 2014 May 23;13:119. Epub 2014 May 23.

Laboratory of Molecular Oncology, Clinic of Oncology, University Hospital Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1186/1476-4598-13-119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039656PMC
May 2014

Hippo/YAP pathway for targeted therapy.

Transl Lung Cancer Res 2014 Apr;3(2):75-83

Laboratory of Molecular Oncology, Clinic of Oncology, University Hospital of Zürich, Häldeliweg 4, 8044 Zürich, Switzerland.

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http://dx.doi.org/10.3978/j.issn.2218-6751.2014.02.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367659PMC
April 2014

PI3K/mTOR signaling in mesothelioma patients treated with induction chemotherapy followed by extrapleural pneumonectomy.

J Thorac Oncol 2014 Feb;9(2):239-47

*Division of Thoracic Surgery, University Hospital of Zürich, Zürich, Switzerland; †Institute of Surgical Pathology, University Hospital Zürich, Zürich, Switzerland; ‡Laboratory of Molecular Oncology, University of Zürich, Zürich, Switzerland; §Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; ‖Division of Thoracic Surgery, Toronto General Hospital, Toronto, Canada; and ¶Division of Biostatistics, Institute for Social and Preventative Medicine, University of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1097/JTO.0000000000000055DOI Listing
February 2014

Strategies for improving outcomes in NSCLC: a look to the future.

Lung Cancer 2013 Dec 8;82(3):375-82. Epub 2013 Sep 8.

Department of Oncology, University Hospital Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2013.08.025DOI Listing
December 2013

Identification of a seven glycopeptide signature for malignant pleural mesothelioma in human serum by selected reaction monitoring.

Clin Proteomics 2013 Nov 8;10(1):16. Epub 2013 Nov 8.

Department of Biology, Institute of Molecular Systems Biology, Swiss Federal Institute of Technology (ETH) Zürich, Wolfgang-Pauli Strasse 16, 8093 Zürich, Switzerland.

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http://clinicalproteomicsjournal.biomedcentral.com/articles/
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http://dx.doi.org/10.1186/1559-0275-10-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827840PMC
November 2013

Treatment and detection of ALK-rearranged NSCLC.

Lung Cancer 2013 Aug 12;81(2):145-54. Epub 2013 Jun 12.

Department of Oncology, University Hospital of Vaudois (CHUV), Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.lungcan.2013.03.017DOI Listing
August 2013

Pemetrexed-induced neutropenic enteritis and severe cutaneous hyperpigmentation in a patient with malignant pleural mesothelioma.

Lung Cancer 2013 Jun 19;80(3):347-9. Epub 2013 Mar 19.

Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.lungcan.2013.02.019DOI Listing
June 2013

[In Process Citation].

Praxis (Bern 1994) 2013 Apr;102(9):503-12

Klinik und Poliklinik für Innere Medizin, Universitätsspital Zürich.

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http://dx.doi.org/10.1024/1661-8157/a001306DOI Listing
April 2013

Differential effects of lovastatin on cisplatin responses in normal human mesothelial cells versus cancer cells: implication for therapy.

PLoS One 2012 17;7(9):e45354. Epub 2012 Sep 17.

Laboratory of Molecular Oncology, University Hospital of Zürich, University of Zürich, Zürich, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0045354PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444484PMC
February 2013

Survival of patients treated surgically for synchronous single-organ metastatic NSCLC and advanced pathologic TN stage.

Lung Cancer 2012 Dec 3;78(3):234-8. Epub 2012 Oct 3.

Division of Thoracic Surgery, University Hospital Zurich, Rämistrasse 100, CH-8091 Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.lungcan.2012.09.011DOI Listing
December 2012

Inhibition of phosphoinositide-3 kinase pathway down regulates ABCG2 function and sensitizes malignant pleural mesothelioma to chemotherapy.

Lung Cancer 2012 Oct 1;78(1):23-9. Epub 2012 Aug 1.

Molecular Oncology, Clinic for Oncology, University Hospital Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.lungcan.2012.07.005DOI Listing
October 2012

Role of hedgehog signaling in malignant pleural mesothelioma.

Clin Cancer Res 2012 Sep 25;18(17):4646-56. Epub 2012 Jun 25.

Laboratory of Molecular Oncology, Clinic and Policlinic of Oncology, Division of Thoracic Surgery, Institute of Surgical Pathology, University Hospital Zürich, Zurich, Switzerland.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-12-0599DOI Listing
September 2012

ALK translocation and crizotinib in non-small cell lung cancer: an evolving paradigm in oncology drug development.

Eur J Cancer 2012 May 6;48(7):961-73. Epub 2012 Mar 6.

University of Torino San Luigi Hospital, Orbassano, Torino, Italy.

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http://dx.doi.org/10.1016/j.ejca.2012.02.001DOI Listing
May 2012

Biomarker testing in non-small cell lung cancer: to move forward with quality.

Authors:
Rolf Stahel

Clin Transl Oncol 2012 May;14(5):321-2

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http://dx.doi.org/10.1007/s12094-012-0802-6DOI Listing
May 2012

Proteomic surfaceome analysis of mesothelioma.

Lung Cancer 2012 Feb 10;75(2):189-96. Epub 2011 Aug 10.

Clinic of Oncology, University Hospital Zürich, 8044 Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.lungcan.2011.07.009DOI Listing
February 2012

Continued pemetrexed and platin-based chemotherapy in patients with malignant pleural mesothelioma (MPM): value of 18F-FDG-PET/CT.

Eur J Radiol 2012 Jan 3;81(1):e19-25. Epub 2010 Dec 3.

Department of Internal Medicine, Clinic for Medical Oncology, University Hospital Zurich, Switzerland.

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http://linkinghub.elsevier.com/retrieve/pii/S0720048X1000551
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http://dx.doi.org/10.1016/j.ejrad.2010.11.006DOI Listing
January 2012

Treatment decision-making for advanced non-small cell lung cancer and differences among European countries: 1st AIOT-ETOP meeting.

Lung Cancer 2011 Dec 28;74(3):544-8. Epub 2011 Sep 28.

Division of Medical Oncology, S.G. Moscati Hospital, Contrada Amoretta, Avellino, Italy.

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http://dx.doi.org/10.1016/j.lungcan.2011.08.013DOI Listing
December 2011

Inhibition of REV3 expression induces persistent DNA damage and growth arrest in cancer cells.

Neoplasia 2011 Oct;13(10):961-70

Laboratory of Molecular Oncology, Clinic and Polyclinic of Oncology, University Hospital Zurich, Zurich, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201572PMC
http://dx.doi.org/10.1593/neo.11828DOI Listing
October 2011

Pleural mesothelioma side populations have a precursor phenotype.

Carcinogenesis 2011 Sep 5;32(9):1324-32. Epub 2011 Jul 5.

Laboratory of Molecular Oncology, Clinic of Oncology, University Hospital Zürich, Haeldeliweg 4, 8044 Zurich, Switzerland.

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http://dx.doi.org/10.1093/carcin/bgr127DOI Listing
September 2011

Automated ERCC1 immunohistochemistry in non-small cell lung cancer: comparison of anti-ERCC1 antibodies 8F1, D-10, and FL-297.

Appl Immunohistochem Mol Morphol 2011 Mar;19(2):99-105

Institute for Surgical Pathology, Department of Pathology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/PAI.0b013e3181f1feebDOI Listing
March 2011

Induction of senescence markers after neo-adjuvant chemotherapy of malignant pleural mesothelioma and association with clinical outcome: an exploratory analysis.

Eur J Cancer 2011 Jan 29;47(2):326-32. Epub 2010 Oct 29.

Laboratory of Molecular Oncology, Clinic and Policlinic of Oncology, University Hospital of Zürich, Häldeliweg 4, 8044 Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.ejca.2010.09.044DOI Listing
January 2011

Optimized intrapleural cisplatin chemotherapy with a fibrin carrier after extrapleural pneumonectomy: a preclinical study.

J Thorac Cardiovasc Surg 2011 Jan;141(1):65-71

Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.jtcvs.2010.09.032DOI Listing
January 2011

Pneumonectomy is a valuable treatment option after neoadjuvant therapy for stage III non-small-cell lung cancer.

J Thorac Cardiovasc Surg 2010 Jun 24;139(6):1424-30. Epub 2010 Apr 24.

Division of Thoracic Surgery, University Hospital Zurich, CH-8091 Zurich, Switzerland.

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http://linkinghub.elsevier.com/retrieve/pii/S002252231000223
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http://dx.doi.org/10.1016/j.jtcvs.2010.02.039DOI Listing
June 2010

Combined FDG-PET/CT in response evaluation of malignant pleural mesothelioma.

Lung Cancer 2010 Mar 30;67(3):311-7. Epub 2009 May 30.

Department of Medical Radiology, University Hospital Zuerich, Switzerland.

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http://dx.doi.org/10.1016/j.lungcan.2009.04.015DOI Listing
March 2010

Pemetrexed in the treatment of malignant mesothelioma: results from an expanded access program in Germany.

Respir Med 2010 Jan 8;104(1):142-8. Epub 2009 Oct 8.

Department of Pneumology and Thoracic Surgery, Hospital Grosshansdorf, Woehrendamm 80, D-22927 Grosshansdorf, Germany.

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http://dx.doi.org/10.1016/j.rmed.2009.07.019DOI Listing
January 2010

Successful publishing: how to get your paper accepted.

Surg Oncol 2009 Dec 11;18(4):350-6. Epub 2008 Oct 11.

Surgical Oncology, Editor.

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http://dx.doi.org/10.1016/j.suronc.2008.09.001DOI Listing
December 2009

Multimodality strategies in malignant pleural mesothelioma.

Semin Thorac Cardiovasc Surg 2009 ;21(2):172-6

Division of Thoracic Surgery, University Hospital Zurich, Zürich, Switzerland.

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http://dx.doi.org/10.1053/j.semtcvs.2009.07.004DOI Listing
December 2009

Functional inactivation of NF2/merlin in human mesothelioma.

Lung Cancer 2009 May 4;64(2):140-7. Epub 2008 Oct 4.

Laboratory of Molecular Oncology, Clinic and Policlinic of Oncology, University Hospital of Zürich, Häldeliweg 4, 8044 Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.lungcan.2008.08.014DOI Listing
May 2009

Malignant pleural mesothelioma.

Future Oncol 2009 Apr;5(3):391-402

Laboratory of Molecular Oncology, Clinic and Policlinic of Oncology, University Hosptial, CH-8091 Zürich, Switzerland.

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http://dx.doi.org/10.2217/fon.09.7DOI Listing
April 2009

Improving the outcome in malignant pleural mesothelioma: nonaggressive or aggressive approach?

Curr Opin Oncol 2009 Mar;21(2):124-30

Clinic and Policlinic of Oncology and Thoracic Surgery, University Hospital, Zürich CH 8091, Switzerland.

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http://dx.doi.org/10.1097/CCO.0b013e328324bc30DOI Listing
March 2009