Rolf Bjerkvig

Rolf Bjerkvig

UNVERIFIED PROFILE

Are you Rolf Bjerkvig?   Register this Author

Register author
Rolf Bjerkvig

Rolf Bjerkvig

Publications by authors named "Rolf Bjerkvig"

Are you Rolf Bjerkvig?   Register this Author

98Publications

2532Reads

32Profile Views

Tumor-penetrating peptide for systemic targeting of Tenascin-C.

Sci Rep 2020 Apr 2;10(1):5809. Epub 2020 Apr 2.

Laboratory of Cancer Biology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-020-62760-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118115PMC
April 2020

Reduced expression of proteolipid protein 2 increases ER stress-induced apoptosis and autophagy in glioblastoma.

J Cell Mol Med 2020 Mar 28;24(5):2847-2856. Epub 2019 Nov 28.

Department of Neurosurgery, Qilu Hospital of Shandong University, Shandong Key Laboratory of Brain Functional Remodeling and Brain Science Research Institute, Shandong University, Shandong, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jcmm.14840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077595PMC
March 2020

Interfering with long non-coding RNA MIR22HG processing inhibits glioblastoma progression through suppression of Wnt/β-catenin signalling.

Brain 2020 Feb;143(2):512-530

Department of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University; Shandong Key Laboratory of Brain Function Remodeling, Jinan, 250012, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awz406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009478PMC
February 2020

A validated prognostic nomogram for patients with newly diagnosed lower-grade gliomas in a large-scale Asian cohort.

Neuro Oncol 2020 Feb 6. Epub 2020 Feb 6.

NorLux Neuro-Oncology Laboratory, University of Bergen, Jonas Lies vei, Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/noaa027DOI Listing
February 2020

PMEPA1 isoform a drives progression of glioblastoma by promoting protein degradation of the Hippo pathway kinase LATS1.

Oncogene 2020 Jan 11;39(5):1125-1139. Epub 2019 Oct 11.

Department of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-019-1050-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989403PMC
January 2020

Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma.

EMBO Mol Med 2020 Jan 28;12(1):e10924. Epub 2019 Nov 28.

Shandong Key Laboratory of Brain Function Remodeling, Department of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/emmm.201910924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949512PMC
January 2020

A new chance for EGFR inhibition in glioblastoma?

Neuro Oncol 2019 12;21(12):1487-1488

Department of Biomedicine, University of Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/noz196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917396PMC
December 2019

Long Noncoding RNA Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-κB Signaling.

Clin Cancer Res 2019 Nov 6;25(22):6868-6881. Epub 2019 Sep 6.

Department of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Key Laboratory of Brain Functional Remodeling, Shandong, 107# Wenhua Xi Road, Jinan, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-19-0747DOI Listing
November 2019

Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.

Autophagy 2018 17;14(11):2007-2022. Epub 2018 Aug 17.

a Department of Neurosurgery , Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Key Laboratory of Brain Functional Remodeling , Jinan , Shandong , P.R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15548627.2018.1501133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528PMC
October 2019

Bi-specific tenascin-C and fibronectin targeted peptide for solid tumor delivery.

Biomaterials 2019 Oct 19;219:119373. Epub 2019 Jul 19.

Laboratory of Cancer Biology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, 50411, Tartu, Estonia; Cancer Research Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, 92037, CA, USA; Center for Nanomedicine and Department of Cell, Molecular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, 93106, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biomaterials.2019.119373DOI Listing
October 2019

Peptide-guided nanoparticles for glioblastoma targeting.

J Control Release 2019 Aug 27;308:109-118. Epub 2019 Jun 27.

Laboratory of Cancer Biology, Institute of Biomedicine, Centre of Excellence for Translational Medicine, University of Tartu, Tartu, Estonia; Cancer Research Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, USA; Center for Nanomedicine and Department of Cell, Molecular and Developmental Biology, University of California Santa Barbara, Santa Barbara, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jconrel.2019.06.018DOI Listing
August 2019

Effective Treatment of Metastatic Melanoma by Combining MAPK and PI3K Signaling Pathway Inhibitors.

Int J Mol Sci 2019 Aug 29;20(17). Epub 2019 Aug 29.

Kristian Gerhard Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009 Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20174235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747502PMC
August 2019

Therapeutic Effect of Cabazitaxel and Blood-Brain Barrier opening in a Patient-Derived Glioblastoma Model.

Nanotheranostics 2019 7;3(1):103-112. Epub 2019 Feb 7.

Department of Physics, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7150/ntno.31479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427936PMC
February 2019

Glioblastoma: a prognostic value of AMT-PET?

Neuro Oncol 2019 02;21(2):146-147

Department of Biomedicine, University of Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/noy206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374752PMC
February 2019

Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma.

J Cereb Blood Flow Metab 2018 10 19;38(10):1741-1753. Epub 2017 Jun 19.

7 Norlux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0271678X17714656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168744PMC
October 2018

Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway.

Cancer Med 2018 09 5;7(9):4729-4743. Epub 2018 Aug 5.

Department of Neurosurgery, Qilu Hospital of Shandong University, Brain Science Research Institute, Key Laboratory of Brain Functional Remodeling, Shandong University, Jinan, Shandong, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cam4.1720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143938PMC
September 2018

Six-Transmembrane Epithelial Antigen of Prostate 3 Predicts Poor Prognosis and Promotes Glioblastoma Growth and Invasion.

Neoplasia 2018 06 3;20(6):543-554. Epub 2018 May 3.

Department of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Key Laboratory of Brain Functional Remodeling, Shandong, 107# Wenhua Xi Road, Jinan, 250012, China; K G Jebsen Brain Tumor Research Center, Department of Biomedicine, University of Bergen, 5009, Bergen, Norway. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S14765586173045
Publisher Site
http://dx.doi.org/10.1016/j.neo.2018.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994776PMC
June 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination.

J Exp Clin Cancer Res 2017 09 5;36(1):118. Epub 2017 Sep 5.

Department of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, Jinan, 250012, People's Republic of China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13046-017-0588-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584019PMC
September 2017

Cathepsin L silencing increases AsO toxicity in malignantly transformed pilocytic astrocytoma MPA58 cells by activating caspases 3/7.

Exp Cell Res 2017 07 12;356(1):64-73. Epub 2017 Apr 12.

Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia; Department of Biochemistry, Faculty of Chemistry and Chemical Engineering, University of Ljubljana, Slovenia.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00144827173022
Publisher Site
http://dx.doi.org/10.1016/j.yexcr.2017.04.013DOI Listing
July 2017

Experimental therapies: gene therapies and oncolytic viruses.

Handb Clin Neurol 2016 ;134:183-97

NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg; Department of Biomedicine, University of Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-802997-8.00011-6DOI Listing
December 2016

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

Neuro Oncol 2016 12 10;18(12):1644-1655. Epub 2016 Jun 10.

Department of Biomedicine, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., T.T., K.V., J.A.H., J.V.J., R.J., H.S.S., L.L., T.D., P.Ø.E., R.B., H.M.); KG Jebsen Brain Tumor Research Center, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., K.V., J.A.H., J.V.J., T.D., P. Ø.E., S.P.N., R.B., H.M.); Department of Clinical Science, University of Bergen, Norway (S.K.); Department of Oncology, Haukeland University Hospital, Bergen, Norway (S.K.); Norlux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg (O.K., S.F., S.P.N., R.B.); Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK (A.S.); Department of Clinical Pharmacy, Institute of Pharmacy, Ernst-Moritz-Arndt-University, Greifswald, Germany (S.F., C.A.R.); Department of Neurooncology, University Hospital Heidelberg, Germany (G.S., F.W.); Institute of Scientific Instruments, ASCR, Brno, Czech Republic (R.J.); Edinger-Intsitute, Goethe-University Medical School, Frankfurt am Main, Germany (P.N.H.); Department of Pathology, Haukeland University Hospital, Bergen, Norway (J.A.H., H.M.); Department of Clinical Neurosciences, University of Cambridge, UK (S.G.P., C.W.); Statistics and Computational Biology Laboratory, University of Cambridge, UK (I.S.); Neuro Clinic, Haukeland University Hospital, Bergen, Norway; Department of Experimental Neurology, Charité - Universitätsmedizin Berlin, Germany (P.E.); Department of Systems Medicine, University of Rome «Tor Vergata», Rome, Italy (G.G.); INSERM U1029 - University of Bordeaux, Allée Geoffroy St. Hilaire, Pessac, France (T.D.); Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway (M.L.-J., P. Ø.E.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/now113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791772PMC
December 2016

Rapid Conversion of Mutant IDH1 from Driver to Passenger in a Model of Human Gliomagenesis.

Mol Cancer Res 2016 10 18;14(10):976-983. Epub 2016 Jul 18.

Department of Neurological Surgery, University of California, San Francisco, San Francisco, California.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065766PMC
http://dx.doi.org/10.1158/1541-7786.MCR-16-0141DOI Listing
October 2016

Engraftment of Human Glioblastoma Cells in Immunocompetent Rats through Acquired Immunosuppression.

PLoS One 2015 20;10(8):e0136089. Epub 2015 Aug 20.

K.G. Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, Bergen, Norway; Department of Pathology, Haukeland University Hospital, Bergen, Norway.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136089PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546393PMC
May 2016

Practical Considerations for Omics Experiments in Biomedical Sciences.

Curr Pharm Biotechnol 2016 ;17(1):105-14

Proteomics Unit, Department of Biomedicine, University of Bergen, Norway; Jones Liesvei 91, N-5009 Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1389201016666150817095348DOI Listing
March 2016

Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma.

PLoS One 2015 1;10(5):e0123544. Epub 2015 May 1.

NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health (L.I.H.), Luxembourg, Luxembourg; KG Jebsen Brain Tumour Research Center, Department of Biomedicine, University of Bergen, Bergen, Norway.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123544PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416792PMC
February 2016

Targeted Proteomics to Assess the Response to Anti-Angiogenic Treatment in Human Glioblastoma (GBM).

Mol Cell Proteomics 2016 Feb 4;15(2):481-92. Epub 2015 Aug 4.

From the ‡NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg, Luxembourg; ¶KG Jebsen Brain Tumour Research Center, Department of Biomedicine, University of Bergen, Bergen, Norway

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/mcp.M115.052423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739668PMC
February 2016

Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

FASEB J 2015 Nov 28;29(11):4695-712. Epub 2015 Jul 28.

*Department of Biomedicine, Biomaterials, Department of Clinical Dentistry, and K. G. Jebsen Brain Tumour Research Center, University of Bergen, Bergen, Norway; Department of Pathology and Department of Clinical Medicine, Haukeland University Hospital, Bergen, Norway; and NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health (LIH), Luxembourg, Luxembourg.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.14-268615DOI Listing
November 2015

Melanoma brain metastasis is independent of lactate dehydrogenase A expression.

Neuro Oncol 2015 Oct 19;17(10):1374-85. Epub 2015 Mar 19.

Department of Biomedicine, University of Bergen, Bergen, Norway (T.S., H.E., K.O.S., S.H., E.H., C.B.R., R.Bj., F.T.); Department of Clinical Medicine, University of Bergen, Bergen, Norway (T.S., M.L.-J.); Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway (T.S., M.L.-J.); Edinger-Institute (Neurological Institute), Goethe-University Medical School, Frankfurt am Main, Germany (P.N.H., M.M.); Center for Nuclear Medicine/PET, Department of Oncology and Medical Physics, Haukeland University Hospital, Bergen, Norway (K.E.F.); Department of Dermatology, University Medical Center, Tübingen, Germany (B.W.); Department of Immunology, University of Tübingen, Tübingen, Germany (B.W.); Department of Neuropathology, Institute for Pathology and Neuropathology, University of Tübingen, Tübingen, Germany (R.Be.); Department of Diagnostic and Interventional Neuroradiology, University of Tübingen, Tübingen, Germany (B.B.); NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg (R.Bj.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/nov040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578581PMC
October 2015

Whole genomes redefine the mutational landscape of pancreatic cancer.

Nature 2015 Feb;518(7540):495-501

1] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia [2] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature14169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523082PMC
February 2015

Multimodal imaging of gliomas in the context of evolving cellular and molecular therapies.

Adv Drug Deliv Rev 2014 Sep 28;76:98-115. Epub 2014 Jul 28.

Translational Cancer Research, Department of Biomedicine, University of Bergen, Norway; Molecular Imaging Center, Department of Biomedicine, University of Bergen, Norway; The Kristian Gerhard Jebsen Brain Tumour Research Center, Department of Biomedicine, University of Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.addr.2014.07.010DOI Listing
September 2014

Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?

Biochim Biophys Acta 2014 Aug 18;1846(1):66-74. Epub 2014 Apr 18.

Radboud University Medical Centre, Department of Pathology, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbcan.2014.04.004DOI Listing
August 2014

Bevacizumab treatment for human glioblastoma. Can it induce cognitive impairment?

Neuro Oncol 2014 May;16(5):754-6

Department of Biomedicine, University of Bergen, Norway (P.F., N.O., H.E.,P.Ø.S., R.B); Centre de Recherche Public de la Santé, Luxembourg (D.S., O.K., S.P.N.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/nou013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984560PMC
May 2014

In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways.

Int J Mol Sci 2014 May 16;15(5):8773-94. Epub 2014 May 16.

NorLux Neuro-Oncology Laboratory, Department of Biomedicine, University of Bergen, 5009 Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms15058773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057758PMC
May 2014

Cathepsin L silencing enhances arsenic trioxide mediated in vitro cytotoxicity and apoptosis in glioblastoma U87MG spheroids.

Exp Cell Res 2013 Oct 19;319(17):2637-48. Epub 2013 Aug 19.

Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia; Bia d.o.o., Ljubljana, Slovenia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2013.08.011DOI Listing
October 2013

Loss of adipocyte specification and necrosis augment tumor-associated inflammation.

Adipocyte 2013 Jul 19;2(3):176-83. Epub 2013 Apr 19.

Department of Biomedicine; University of Bergen; Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/adip.24472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756107PMC
July 2013

In vivo animal models for studying brain metastasis: value and limitations.

Clin Exp Metastasis 2013 Jun 16;30(5):695-710. Epub 2013 Jan 16.

NorLux Neuro-Oncology Laboratory, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5019, Bergen, Norway.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10585-013-9566-9
Publisher Site
http://dx.doi.org/10.1007/s10585-013-9566-9DOI Listing
June 2013

Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells.

Brain 2013 May 4;136(Pt 5):1462-75. Epub 2013 Mar 4.

NorLux Neuro-Oncology Laboratory, Centre de Recherche Public de la Santé (CRP-Santé), Department of Oncology NorLux Neuro-Oncology Laboratory 84, Val Fleuri, L- 1526 Luxembourg.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awt025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634193PMC
May 2013

In vivo bioluminescence imaging validation of a human biopsy-derived orthotopic mouse model of glioblastoma multiforme.

Mol Imaging 2013 May;12(3):161-72

Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.

View Article

Download full-text PDF

Source
May 2013

Mesenchymal stem cell signaling in cancer progression.

Cancer Treat Rev 2013 Apr 9;39(2):180-8. Epub 2012 Apr 9.

Department of Biomedicine, University of Bergen, Jonas Lies vei 91, N-5020 Bergen, Norway.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03057372120005
Publisher Site
http://dx.doi.org/10.1016/j.ctrv.2012.03.005DOI Listing
April 2013

The DNA repair protein ALKBH2 mediates temozolomide resistance in human glioblastoma cells.

Neuro Oncol 2013 Mar 20;15(3):269-78. Epub 2012 Dec 20.

Department of Biomedicine, University of Bergen, Jonas Lies vei 91, N-5009, Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/nos301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578482PMC
March 2013

Tumor vasculature: the Achilles' heel of cancer?

Expert Opin Ther Targets 2013 Jan 2;17(1):7-20. Epub 2012 Nov 2.

University of Bergen, Department of Biomedicine, Jonas Lies vei 91, 5009 Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/14728222.2013.730522DOI Listing
January 2013

Spontaneous transformation of stem cells in vitro and the issue of cross-contamination.

Int J Biol Sci 2012 15;8(7):1051-2; discussion 1053-4. Epub 2012 Aug 15.

Department of Biomedicine, University of Bergen, Jonas Lies vei 91, N-5020 Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7150/ijbs.3665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432851PMC
November 2012

The regulation of cysteine cathepsins and cystatins in human gliomas.

Int J Cancer 2012 Oct 9;131(8):1779-89. Epub 2012 Mar 9.

Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.27453DOI Listing
October 2012

Cellular host responses to gliomas.

PLoS One 2012 23;7(4):e35150. Epub 2012 Apr 23.

Department of Neurosciences, City of Hope National Medical Center and Beckman Research Institute, Duarte, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035150PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335155PMC
September 2012

In vivo models of primary brain tumors: pitfalls and perspectives.

Neuro Oncol 2012 Aug 7;14(8):979-93. Epub 2012 Jun 7.

NorLux, Neuro-Oncology Laboratory, Department of Biomedicine, University of Bergen, Bergen, Norway.

View Article

Download full-text PDF

Source
https://academic.oup.com/neuro-oncology/article-lookup/doi/1
Publisher Site
http://dx.doi.org/10.1093/neuonc/nos135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408261PMC
August 2012

The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling.

Blood 2012 Jul 12;120(4):847-57. Epub 2012 Jun 12.

Department of Microbiology, Institute of Clinical Biochemistry and Centre of Molecular Biology and Neuroscience, Oslo University Hospital and University of Oslo, Rikshospitalet, Oslo, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2011-10-388496DOI Listing
July 2012

Molecular mechanisms of temozolomide resistance in glioblastoma multiforme.

Expert Rev Anticancer Ther 2012 May;12(5):635-42

NorLux Neuro-Oncology, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/era.12.37DOI Listing
May 2012

NUMB does not impair growth and differentiation status of experimental gliomas.

Exp Cell Res 2011 Dec 12;317(20):2864-73. Epub 2011 Sep 12.

Department of Biomedicine, University of Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2011.09.002DOI Listing
December 2011

Critical appraisal of the side population assay in stem cell and cancer stem cell research.

Cell Stem Cell 2011 Feb;8(2):136-47

NorLux Neuro-Oncology Laboratory, Oncology Department, Centre de Recherche Public de la Santé, 84 Val Fleuri, Luxembourg.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2011.01.007DOI Listing
February 2011

Subcellular distribution of nuclear import-defective isoforms of the promyelocytic leukemia protein.

BMC Mol Biol 2010 Nov 21;11:89. Epub 2010 Nov 21.

Department of Biomedicine, University of Bergen, Jonas Lies Vei 91, 5009 Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2199-11-89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998510PMC
November 2010

αB-crystallin is elevated in highly infiltrative apoptosis-resistant glioblastoma cells.

Am J Pathol 2010 Oct 2;177(4):1618-28. Epub 2010 Sep 2.

Department of Oncology and Medical Physics, Haukeland University Hospital, Jonas Lies vei 91, 5009 Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2353/ajpath.2010.090063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947259PMC
October 2010

Interstitial fluid: the overlooked component of the tumor microenvironment?

Fibrogenesis Tissue Repair 2010 Jul 23;3:12. Epub 2010 Jul 23.

Department of Biomedicine, University of Bergen, Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1755-1536-3-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920231PMC
July 2010

Glioma cell populations grouped by different cell type markers drive brain tumor growth.

Cancer Res 2010 Jun 11;70(11):4274-9. Epub 2010 May 11.

Oncomatrix Research Lab, Department of Biomedicine and Norlux Neuro-Oncology, Department of Biomedicine, University of Bergen, Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-09-3904DOI Listing
June 2010

Cancer stem cells and angiogenesis.

Semin Cancer Biol 2009 Oct 7;19(5):279-84. Epub 2009 Oct 7.

NorLux Neuro-Oncology, Department of Biomedicine, University of Bergen, N-5009, Bergen, Norway.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcancer.2009.09.001DOI Listing
October 2009