Roland Penzel

Roland Penzel

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Roland Penzel

Roland Penzel

Publications by authors named "Roland Penzel"

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Genetic profiling of melanoma in routine diagnostics: assay performance and molecular characteristics in a consecutive series of 274 cases.

Pathology 2018 Dec 20;50(7):703-710. Epub 2018 Oct 20.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany; German Cancer Consortium (DKTK), Partner Site, Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pathol.2018.08.004DOI Listing
December 2018

Targeted molecular profiling reveals genetic heterogeneity of poromas and porocarcinomas.

Pathology 2018 Apr 18;50(3):327-332. Epub 2017 Dec 18.

Institute of Pathology, University of Heidelberg, Heidelberg, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pathol.2017.10.011DOI Listing
April 2018

Analysis of the proliferative activity in lung adenocarcinomas with specific driver mutations.

Pathol Res Pract 2018 Mar 2;214(3):408-416. Epub 2018 Jan 2.

Institute of Pathology, University Heidelberg, Heidelberg, Germany; Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2017.12.018DOI Listing
March 2018

Screening for Helicobacter pylori in Idiopathic Pulmonary Fibrosis Lung Biopsies.

Respiration 2016 9;91(1):3-8. Epub 2015 Dec 9.

Centre for Interstitial and Rare Lung Diseases, Department of Pneumology and Respiratory Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000442449DOI Listing
October 2016

Microsatellite instability in pulmonary adenocarcinomas: a comprehensive study of 480 cases.

Virchows Arch 2016 Mar 4;468(3):313-9. Epub 2015 Dec 4.

Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00428-015-1892-7DOI Listing
March 2016

Genetic heterogeneity in synchronous colorectal cancers impacts genotyping approaches and therapeutic strategies.

Genes Chromosomes Cancer 2016 Mar 9;55(3):268-77. Epub 2015 Dec 9.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/gcc.22330DOI Listing
March 2016

High-throughput diagnostic profiling of clinically actionable gene fusions in lung cancer.

Genes Chromosomes Cancer 2016 Jan 23;55(1):30-44. Epub 2015 Sep 23.

Institute of Pathology, University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1002/gcc.22297DOI Listing
January 2016

NUT carcinoma of the thorax: Case report and review of the literature.

Lung Cancer 2015 Dec 9;90(3):484-91. Epub 2015 Oct 9.

Institute of Pathology, University Hospital Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.10.001DOI Listing
December 2015

ALK-FISH borderline cases in non-small cell lung cancer: Implications for diagnostics and clinical decision making.

Lung Cancer 2015 Dec 23;90(3):465-71. Epub 2015 Oct 23.

Institute of Pathology, Charité Universitätsmedizin, Charitéplatz 1, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.09.022DOI Listing
December 2015

Semiconductor-based sequencing of formalin-fixed, paraffin-embedded colorectal cancer samples.

Oncologist 2015 May 10;20(5):e10-1. Epub 2015 Apr 10.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany; National Center for Tumor Diseases, Heidelberg, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany.

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http://dx.doi.org/10.1634/theoncologist.2014-0280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425379PMC
May 2015

Multicenter immunohistochemical ALK-testing of non-small-cell lung cancer shows high concordance after harmonization of techniques and interpretation criteria.

J Thorac Oncol 2014 Nov;9(11):1685-92

*Institute of Pathology, Charité BERLIN, Berlin, Germany; †Institute of Pathology, University of Heidelberg, Heidelberg, Germany; ‡Department of Pathology, Aberdeen University Medical School, Aberdeen, United Kingdom; §Department of Pathology and Cytology, Karolinska University Hospital, Solna, Stockholm, Sweden; ‖Department of Pathology, University Hospital Cologne, Cologne, Germany; ¶Laboratorio de Dianas Terapeuticas, Hospital Universitario Sanchinarro, Madrid, Spain; #Institute of Pathology, Klinikum Großhadern Ludwig-Maximilians-Universität, Munich, Germany; **Institute of Pathology, UZ ANTWERPEN, Edegem, Belgium; ††Institute of Pathology, Klinikum rechts der Isar, TU, Munich, Germany; ‡‡Institute of Pathology, University Hospital Carl Gustav Carus, Dresden, Germany; §§Institute of Pathology, Universitätsspital Basel, Basel, Germany; ‖‖Institute of Pathology, HSK Dr.-Horst-Schmidt-Kliniken GmbH, Wiesbaden, Germany; ¶¶Institute of Pathology, Universitäts Spital Zürich, Zurich, Switzerland; ##Institute of Pathology, Centre Jean Perrin, Clermont-Ferrand, France; ***Patologisk Institut, Århus Universitetshospital, Århus, Denmark; †††Pathology-Berlin, Bioptisches Institut Gemeinschaftspraxis für Pathologie, Berlin, Germany.

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http://dx.doi.org/10.1097/JTO.0000000000000332DOI Listing
November 2014

Comparison of molecular abnormalities in vulvar and vaginal melanomas.

Mod Pathol 2014 Oct 7;27(10):1386-93. Epub 2014 Mar 7.

Department of Gynecology, Tuebingen University Hospital, Tuebingen, Germany.

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http://dx.doi.org/10.1038/modpathol.2013.211DOI Listing
October 2014

Multicenter ALK testing in non-small-cell lung cancer: results of a round robin test.

J Thorac Oncol 2014 Oct;9(10):1464-9

*Institute of Pathology, Humboldt University Berlin, Campus Charité Mitte, Charité Universitätsmedizin, Berlin, Germany; and †Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/JTO.0000000000000307DOI Listing
October 2014

ROS1 expression and translocations in non-small-cell lung cancer: clinicopathological analysis of 1478 cases.

Histopathology 2014 Aug 3;65(2):187-94. Epub 2014 Apr 3.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1111/his.12379DOI Listing
August 2014

A current perspective on the pathological assessment of FOXL2 in adult-type granulosa cell tumours of the ovary.

Histopathology 2014 Feb 6;64(3):380-8. Epub 2013 Nov 6.

Department of Obstetrics and Gynaecology, Eberhard Karls Universität Tübingen, Tübingen, Germany; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://doi.wiley.com/10.1111/his.12253
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http://dx.doi.org/10.1111/his.12253DOI Listing
February 2014

Targeting the BRAF V600E mutation in multiple myeloma.

Cancer Discov 2013 Aug 23;3(8):862-9. Epub 2013 Apr 23.

Department of General Pathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0014DOI Listing
August 2013

Application of a BRAF V600E mutation-specific antibody for the diagnosis of hairy cell leukemia.

Am J Surg Pathol 2012 Dec;36(12):1796-800

Department of General Pathology, Institute of Pathology, Ruprecht-Karls-University Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/PAS.0b013e3182549b50DOI Listing
December 2012

MicroRNA profiling of primary high-grade soft tissue sarcomas.

Genes Chromosomes Cancer 2012 Nov 18;51(11):982-96. Epub 2012 Jul 18.

Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1002/gcc.21980DOI Listing
November 2012

Transitions between flat epithelial atypia and low-grade ductal carcinoma in situ of the breast.

Am J Surg Pathol 2012 Aug;36(8):1247-52

Institute of Pathology, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.1097/PAS.0b013e31825f9d6aDOI Listing
August 2012

A novel EML4-ALK variant: exon 6 of EML4 fused to exon 19 of ALK.

J Thorac Oncol 2012 Jul;7(7):1198-9

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/JTO.0b013e3182598af3DOI Listing
July 2012

Clonality of multifocal nonsmall cell lung cancer: implications for staging and therapy.

Eur Respir J 2012 Jun 10;39(6):1437-42. Epub 2011 Nov 10.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1183/09031936.00105911DOI Listing
June 2012

Optimized algorithm for Sanger sequencing-based EGFR mutation analyses in NSCLC biopsies.

Virchows Arch 2012 Apr 15;460(4):407-14. Epub 2012 Mar 15.

Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 220/221, 69120, Heidelberg, Germany.

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http://link.springer.com/10.1007/s00428-012-1219-x
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http://dx.doi.org/10.1007/s00428-012-1219-xDOI Listing
April 2012

Molecular heterogeneity of TFE3 activation in renal cell carcinomas.

Mod Pathol 2012 Feb 28;25(2):308-15. Epub 2011 Oct 28.

Institute of Pathology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/modpathol.2011.169DOI Listing
February 2012

Stimulation of the calcium-sensing receptor stabilizes the podocyte cytoskeleton, improves cell survival, and reduces toxin-induced glomerulosclerosis.

Kidney Int 2011 Sep 20;80(5):483-92. Epub 2011 Apr 20.

Division of Pediatric Nephrology, Center for Pediatric and Adolescent Medicine, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/ki.2011.105DOI Listing
September 2011

Selective downregulation of retinoic acid-inducible gene I within the intestinal epithelial compartment in Crohn's disease.

Inflamm Bowel Dis 2011 Sep 6;17(9):1943-54. Epub 2011 Jan 6.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ibd.21572DOI Listing
September 2011

Expression and mutation analysis of EGFR, c-KIT, and β-catenin in pulmonary blastoma.

J Clin Pathol 2011 Apr 3;64(4):349-53. Epub 2011 Feb 3.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1136/jcp.2010.085696DOI Listing
April 2011

Moesin-dependent cytoskeleton remodelling is associated with an anaplastic phenotype of pancreatic cancer.

J Cell Mol Med 2010 May 11;14(5):1166-79. Epub 2009 May 11.

Department of General Surgery, Technische Universität München, Ismaningerstrasse 22, 81675 Munich, Germany.

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http://dx.doi.org/10.1111/j.1582-4934.2009.00772.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822753PMC
May 2010

Reduction of CD44(+)/CD24(-) breast cancer cells by conventional cytotoxic chemotherapy.

Hum Pathol 2010 Apr 11;41(4):574-81. Epub 2009 Dec 11.

Institute of Pathology, Heidelberg University, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.humpath.2009.08.023DOI Listing
April 2010

Invasive ductal breast cancer within a malignant phyllodes tumor: case report and assessment of clonality.

Hum Pathol 2010 Feb 6;41(2):293-6. Epub 2009 Nov 6.

Institute of Pathology, Heidelberg University, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.humpath.2009.08.006DOI Listing
February 2010

A primary malignant ependymoma of the abdominal cavity: a case report and review of the literature.

Virchows Arch 2009 Apr 24;454(4):475-8. Epub 2009 Feb 24.

Department of General Pathology, University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00428-009-0744-8DOI Listing
April 2009

Clonality of lobular carcinoma in situ (LCIS) and metachronous invasive breast cancer.

Breast Cancer Res Treat 2008 Feb 23;107(3):331-5. Epub 2007 Mar 23.

Department of Pathology, University of Heidelberg, Im Neuenheimer Feld 220, 69120, Heidelberg, Germany.

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http://link.springer.com/10.1007/s10549-007-9557-0
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http://dx.doi.org/10.1007/s10549-007-9557-0DOI Listing
February 2008

Adrenomedullin is induced by hypoxia and enhances pancreatic cancer cell invasion.

Int J Cancer 2007 Jul;121(1):21-32

Department of General Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.22596DOI Listing
July 2007

Correlation of glypican-1 expression with TGF-beta, BMP, and activin receptors in pancreatic ductal adenocarcinoma.

Int J Oncol 2006 Nov;29(5):1139-48

Department of General Surgery, University of Heidelberg, D-69120 Heidelberg, Germany.

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November 2006

Recurrent herpes simplex virus hepatitis after liver retransplantation despite acyclovir therapy.

Liver Transpl 2005 Oct;11(10):1289-94

Institute of Pathology, Department of General Pathology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/lt.20567DOI Listing
October 2005