Publications by authors named "Roland P Kuiper"

76Publications

Natural gene therapy in hematopoietic disorders: GATA too.

Blood 2020 Aug;136(8):923-924

Princess Máxima Center for Pediatric Oncology.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood.2020007001DOI Listing
August 2020

Outcomes of patients with childhood B-cell precursor acute lymphoblastic leukaemia with late bone marrow relapses: long-term follow-up of the ALLR3 open-label randomised trial.

Lancet Haematol 2019 Apr 27;6(4):e204-e216. Epub 2019 Feb 27.

Childrens Cancer Group, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; Tata Translational Cancer Research Centre, Tata Medical Center, New Town, Kolkata, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2352-3026(19)30003-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445853PMC
April 2019

Somatic reversion events point towards as a novel disease gene in a condition resembling Diamond-Blackfan anemia.

Haematologica 2018 12 13;103(12):e607-e609. Epub 2018 Sep 13.

Department of Human Genetics, Radboud university medical center and Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2018.200683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269308PMC
December 2018

NTHL1 and MUTYH polyposis syndromes: two sides of the same coin?

J Pathol 2018 02 14;244(2):135-142. Epub 2017 Dec 14.

Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/path.5002DOI Listing
February 2018

Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer.

Science 2017 10 14;358(6360):234-238. Epub 2017 Sep 14.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, 3584CT Utrecht, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aao3130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038908PMC
October 2017

Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early-onset colorectal cancer.

Genes Chromosomes Cancer 2016 11 7;55(11):855-63. Epub 2016 Jul 7.

Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22385DOI Listing
November 2016

Recognition of genetic predisposition in pediatric cancer patients: An easy-to-use selection tool.

Eur J Med Genet 2016 Mar 26;59(3):116-25. Epub 2016 Jan 26.

Department of Human Genetics, Radboud University Medical Center and Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejmg.2016.01.008DOI Listing
March 2016

NTHL1 defines novel cancer syndrome.

Oncotarget 2015 Oct;6(33):34069-70

Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.5864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741436PMC
October 2015

Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases.

World J Gastroenterol 2015 Apr;21(14):4136-49

Jun-Xiao Zhang, Richarda M de Voer, Marc-Manuel Hahn, Eugène TP Verwiel, Marjolijn JL Ligtenberg, Nicoline Hoogerbrugge, Roland P Kuiper, Ad Geurts van Kessel, Department of Human Genetics, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3748/wjg.v21.i14.4136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394074PMC
April 2015

Perivascular epithelioid cell tumor of gastrointestinal tract: case report and review of the literature.

Medicine (Baltimore) 2015 Jan;94(3):e393

From the Guangdong Institute of Gastroenterology and the Sixth Affiliated Hospital, (BL, CW, JZ, MS, XZ, SS, JW, HL); Guangdong Key Laboratory of Colorectal and Pelvic Floor Diseases, (BL, CW, JZ, MS, XZ, JW, HL); Institute of Human Virology, (BL, CW, JZ, MS, XZ, HL) Key Laboratory of Tropical Disease Control (Ministry of Education); Sun Yat-sen University, Guangzhou (BL, CW, JZ, MS, XZ, HL); Dongguan Health School, Dongguan, China (BL); Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands (JZ, RPK, AGK); and Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan (AI).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000000393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602642PMC
January 2015

DNA copy number alterations mark disease progression in paediatric chronic myeloid leukaemia.

Br J Haematol 2014 Jul 27;166(2):250-3. Epub 2014 Mar 27.

Division of Paediatric Oncology/Haematology, Department of Paediatrics, Beatrix Children's Hospital, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.12850DOI Listing
July 2014

A RAG driver on the road to pediatric ALL.

Nat Genet 2014 Feb;46(2):96-8

Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands, and with the Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2879DOI Listing
February 2014

EPCAM deletion carriers constitute a unique subgroup of Lynch syndrome patients.

Fam Cancer 2013 Jun;12(2):169-74

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10689-012-9591-xDOI Listing
June 2013

The epigenetics of (hereditary) colorectal cancer.

Cancer Genet Cytogenet 2010 Nov;203(1):1-6

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Centre for Oncology, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cancergencyto.2010.08.013DOI Listing
November 2010

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes.

Nat Genet 2010 Aug 4;42(8):665-7. Epub 2010 Jul 4.

Department of Laboratory Medicine, Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.620DOI Listing
August 2010

Germline copy number variation and cancer risk.

Curr Opin Genet Dev 2010 Jun 8;20(3):282-9. Epub 2010 Apr 8.

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gde.2010.03.005DOI Listing
June 2010

BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia.

Blood 2010 Jun 30;115(23):4810-9. Epub 2010 Mar 30.

Department of Pediatrics, Laboratory of Pediatric Oncology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/content/115/23/4810.full.pdf
Web Search
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2009-05-22
Publisher Site
http://dx.doi.org/10.1182/blood-2009-05-223081DOI Listing
June 2010

Acquired mutations in TET2 are common in myelodysplastic syndromes.

Nat Genet 2009 Jul 31;41(7):838-42. Epub 2009 May 31.

Department of Hematology and Central Hematology Laboratory, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.391DOI Listing
July 2009

Mapping of constitutional translocation breakpoints in renal cell cancer patients: identification of KCNIP4 as a candidate gene.

Cancer Genet Cytogenet 2007 Nov;179(1):11-8

Department of Human Genetics, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cancergencyto.2007.07.005DOI Listing
November 2007

Regulation of the MiTF/TFE bHLH-LZ transcription factors through restricted spatial expression and alternative splicing of functional domains.

Nucleic Acids Res 2004 26;32(8):2315-22. Epub 2004 Apr 26.

Department of Human Genetics, University Medical Center Nijmegen, Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkh571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC419459PMC
May 2004

Upregulation of the transcription factor TFEB in t(6;11)(p21;q13)-positive renal cell carcinomas due to promoter substitution.

Hum Mol Genet 2003 Jul;12(14):1661-9

Department of Human Genetics, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddg178DOI Listing
July 2003

Cell-type-specific and selectively induced expression of members of the p24 family of putative cargo receptors.

J Cell Sci 2002 Mar;115(Pt 5):1049-58

Department of Molecular Animal Physiology, Nijmegen Center for Molecular Life Sciences (NCMLS), University of Nijmegen, Geert Grooteplein Zuid 28, 6525 GA Nijmegen, The Netherlands.

View Article

Download full-text PDF

Source
March 2002