Roland Kolbeck

Roland Kolbeck

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Roland Kolbeck

Roland Kolbeck

Publications by authors named "Roland Kolbeck"

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Benralizumab for -Negative Hypereosinophilic Syndrome.

N Engl J Med 2019 04;380(14):1336-1346

From the Laboratory of Parasitic Diseases (F.L.K., F.L., M.M., J.W., L.W., T.B., T.M., B.P., P.Y., P.K., A.D.K.) and Biostatistics Research Branch (M.P.F.), National Institute of Allergy and Infectious Diseases, the Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (H.A., S.K.), and the Laboratory of Pathology, National Cancer Institute (A.P., M.Q.), National Institutes of Health (NIH), and the Departments of Laboratory Medicine (J.H.E., X.S., I.M.) and Transfusion Medicine (S.R.P.), NIH Clinical Center, Bethesda, Washington Adventist Hospital, Takoma Park (T.M.), and MedImmune (N.L., R.K.) and AstraZeneca (P.N., M.G.), Gaithersburg - all in Maryland; the Department of Veteran Affairs, Tennessee Valley Healthcare System, Chattanooga (J.H.E.); and MedImmune, South San Francisco, CA (L.Y.).

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http://dx.doi.org/10.1056/NEJMoa1812185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557265PMC
April 2019

Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond.

Adv Drug Deliv Rev 2019 Feb 13;141:92-103. Epub 2018 Dec 13.

MedImmune, Gaithersburg, MD 20878, United States. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2018.12.005DOI Listing
February 2019

Lifelong memory responses perpetuate humoral T2 immunity and anaphylaxis in food allergy.

J Allergy Clin Immunol 2017 Dec 16;140(6):1604-1615.e5. Epub 2017 Feb 16.

McMaster Immunology Research Centre (MIRC), Department of Pathology & Molecular Medicine, McMaster University, Hamilton, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749173023
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http://dx.doi.org/10.1016/j.jaci.2017.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298600PMC
December 2017

IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression.

J Immunol 2017 11 22;199(9):3316-3325. Epub 2017 Sep 22.

Department of Oncology Research, MedImmune, Gaithersburg, MD 20878; and

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http://dx.doi.org/10.4049/jimmunol.1700152DOI Listing
November 2017

Plasmacytoid dendritic cells in autoimmunity.

Curr Opin Immunol 2017 Feb 14;44:20-25. Epub 2016 Nov 14.

Dept of Respiratory, Inflammation & Autoimmunity, MedImmune LLC, Gaithersburg, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2016.10.006DOI Listing
February 2017

Pathogenic mechanisms of IgE-mediated inflammation in self-destructive autoimmune responses.

Autoimmunity 2017 Feb;50(1):25-36

a Department of Respiratory , Inflammation & Autoimmunity, MedImmune LLC , Gaithersburg , MD , USA.

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http://dx.doi.org/10.1080/08916934.2017.1280670DOI Listing
February 2017

Monoclonal antibody therapy for the treatment of asthma and chronic obstructive pulmonary disease with eosinophilic inflammation.

Pharmacol Ther 2017 01 20;169:57-77. Epub 2016 Oct 20.

MedImmune LLC, Gaithersburg, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2016.10.016DOI Listing
January 2017

RAGE Enhances TLR Responses through Binding and Internalization of RNA.

J Immunol 2016 11 19;197(10):4118-4126. Epub 2016 Oct 19.

Institute of Innate Immunity, University Hospital, University of Bonn, 53127 Bonn, Germany;

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http://dx.doi.org/10.4049/jimmunol.1502169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062438PMC
November 2016

Complement C5a induces PD-L1 expression and acts in synergy with LPS through Erk1/2 and JNK signaling pathways.

Sci Rep 2016 09 14;6:33346. Epub 2016 Sep 14.

Department of Respiratory, Inflammation and Autoimmunity, MedImmune, LLC. One Medimmune Way, Gaithersburg, MD 20878, USA.

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http://dx.doi.org/10.1038/srep33346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022031PMC
September 2016

Role of IgE in autoimmunity.

J Allergy Clin Immunol 2016 06 27;137(6):1651-1661. Epub 2016 Apr 27.

Respiratory, Inflammation & Autoimmunity Department, Research, MedImmune, Gaithersburg, Md.

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http://dx.doi.org/10.1016/j.jaci.2016.04.007DOI Listing
June 2016

Complement C5a potentiates uric acid crystal-induced IL-1β production.

Eur J Immunol 2014 Dec 28;44(12):3669-79. Epub 2014 Oct 28.

Department of Respiratory, Inflammation and Autoimmune Diseases, MedImmune, LLC, Gaithersburg, MD, USA.

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http://dx.doi.org/10.1002/eji.201444560DOI Listing
December 2014

Cigarette smoke primes the pulmonary environment to IL-1α/CXCR-2-dependent nontypeable Haemophilus influenzae-exacerbated neutrophilia in mice.

J Immunol 2014 Sep 4;193(6):3134-45. Epub 2014 Aug 4.

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario L8S 4K1, Canada; Department of Medicine, Firestone Institute for Respiratory Health at St. Joseph's Healthcare, McMaster University, Hamilton, Ontario L8N 4A6, Canada.

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http://dx.doi.org/10.4049/jimmunol.1302412DOI Listing
September 2014

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model.

J Exp Med 2014 Sep 1;211(10):1977-91. Epub 2014 Sep 1.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110

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http://dx.doi.org/10.1084/jem.20132620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172228PMC
September 2014

Pharmacological inhibition of type I interferon signaling protects mice against lethal sepsis.

J Infect Dis 2014 Mar 11;209(6):960-70. Epub 2013 Nov 11.

Inflammation Research Center, Flanders Institute for Biotechnology.

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http://dx.doi.org/10.1093/infdis/jit600DOI Listing
March 2014

Noncanonical autophagy: one small step for LC3, one giant leap for immunity.

Curr Opin Immunol 2014 Feb 30;26:69-75. Epub 2013 Nov 30.

RIA, Research Department, MedImmune, Gaithersburg, MD 20878, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2013.10.012DOI Listing
February 2014

Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia.

J Allergy Clin Immunol 2013 Nov 16;132(5):1086-1096.e5. Epub 2013 Jul 16.

Faculté de médecine, département de médecine, Université Laval, Quebec City, Quebec, Canada. Electronic address:

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http://linkinghub.elsevier.com/retrieve/pii/S009167491300838
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http://dx.doi.org/10.1016/j.jaci.2013.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172321PMC
November 2013

Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands.

Eur J Immunol 2013 Jul 8;43(7):1727-34. Epub 2013 May 8.

Respiratory, Inflammatory, and Autoimmune Diseases Research, MedImmune, LLC, Gaithersburg, MD 20878, USA.

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http://dx.doi.org/10.1002/eji.201242779DOI Listing
July 2013

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization.

J Allergy Clin Immunol 2013 Jan 21;131(1):187-200.e1-8. Epub 2012 Sep 21.

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jaci.2012.08.002DOI Listing
January 2013

Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice.

Respir Res 2012 Sep 19;13:81. Epub 2012 Sep 19.

Department of Pathology and Molecular Medicine, McMaster Immunology Research Centre, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1186/1465-9921-13-81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519608PMC
September 2012

Role of YKL-40 in bronchial smooth muscle remodeling in asthma.

Am J Respir Crit Care Med 2012 Apr 26;185(7):715-22. Epub 2012 Jan 26.

Université Bordeaux, Centre de Recherche Cardio-Thoracique de Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1164/rccm.201105-0915OCDOI Listing
April 2012

Shifting of immune responsiveness to house dust mite by influenza A infection: genomic insights.

J Immunol 2012 Jan 14;188(2):832-43. Epub 2011 Dec 14.

Division of Respiratory Diseases and Allergy, Center for Gene Therapeutics, McMaster University, Hamilton, Ontario L8S 4K1, Canada.

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http://dx.doi.org/10.4049/jimmunol.1102349DOI Listing
January 2012

IL-5 receptor α levels in patients with marked eosinophilia or mastocytosis.

J Allergy Clin Immunol 2011 Nov 16;128(5):1086-92.e1-3. Epub 2011 Jul 16.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.

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http://dx.doi.org/10.1016/j.jaci.2011.05.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205313PMC
November 2011

IL-9 is a Th17-derived cytokine that limits pathogenic activity in organ-specific autoimmune disease.

Eur J Immunol 2011 Apr 24;41(4):952-62. Epub 2011 Feb 24.

Respiratory, Inflammation and Autoimmune Diseases Research, MedImmune, LLC, Gaithersburg, MD, USA.

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http://dx.doi.org/10.1002/eji.201040879DOI Listing
April 2011

Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease.

Am J Respir Crit Care Med 2010 May 4;181(9):917-27. Epub 2010 Feb 4.

Institut National de la Santé et de la Recherche Médicale (INSERM) U700, Physiopathologie et Epidémiologie de l'Insuffisance Respiratoire, Paris, France.

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http://dx.doi.org/10.1164/rccm.200903-0340OCDOI Listing
May 2010

Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF.

Nat Neurosci 2008 Feb 20;11(2):131-3. Epub 2008 Jan 20.

Biozentrum, University of Basel, Klingelbergstrasse 50/70, CH-4056 Basel, Switzerland.

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http://dx.doi.org/10.1038/nn2038DOI Listing
February 2008

Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8.

Mol Pharmacol 2007 Aug;72(2):327-40

Laboratory for Molecular Pharmacology, Department of Pharmacology, The Panum Institute, Copenhagen University, Blegdamsvej 2, 2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1124/mol.106.035543DOI Listing
August 2007

Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8.

J Med Chem 2007 Feb;50(3):566-84

Department of Medicinal Chemistry, Department of Pharmacology, and Drug Safety and Disposition, Millennium Pharmaceuticals, 40 Landsdowne Street, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1021/jm061118eDOI Listing
February 2007

Major reduction of atherosclerosis in fractalkine (CX3CL1)-deficient mice is at the brachiocephalic artery, not the aortic root.

Proc Natl Acad Sci U S A 2004 Dec 13;101(51):17795-800. Epub 2004 Dec 13.

Laboratory of Biochemical Genetics and Metabolism, The Rockefeller University, New York, NY 10021, USA.

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http://dx.doi.org/10.1073/pnas.0408096101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC539720PMC
December 2004

Absence of CCR8 does not impair the response to ovalbumin-induced allergic airway disease.

J Immunol 2003 Feb;170(4):2138-46

Departamento de Inmunología y Oncología, Centro Nacional de Biotecnología/Consejo Superior de Investigaciones Cientificas, Universidad Autónoma de Madrid, Cantoblanco, 28040-Madrid, Spain.

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http://dx.doi.org/10.4049/jimmunol.170.4.2138DOI Listing
February 2003