Publications by authors named "Roland Kappler"

68Publications

Sarcopenia is a prognostic outcome marker in children with high-risk hepatoblastoma.

Authors:
Annika Ritz Julian Kolorz Jochen Hubertus Julia Ley-Zaporozhan Dietrich von Schweinitz Sibylle Koletzko Beate Häberle Irene Schmid Roland Kappler Michael Berger Eberhard Lurz

Pediatr Blood Cancer 2021 Jan 12:e28862. Epub 2021 Jan 12.

Department of Pediatrics, Division of Gastroenterology and Hepatology, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Munich, Germany.

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January 2021

A combined clinical and biological risk classification improves prediction of outcome in hepatoblastoma patients.

Authors:
Stefano Cairo Carolina Armengol Rudolf Maibach Beate Häberle Kristina Becker Juan Carrillo-Reixach Catherine Guettier Christian Vokuhl Irene Schmid Marie-Annick Buendia Sophie Branchereau Dietrich von Schweinitz Roland Kappler

Eur J Cancer 2020 Dec 27;141:30-39. Epub 2020 Oct 27.

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Germany. Electronic address:

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December 2020

SP8 Promotes an Aggressive Phenotype in Hepatoblastoma via FGF8 Activation.

Authors:
Alexandra Elisabeth Wagner Thomas Schwarzmayr Beate Häberle Christian Vokuhl Irene Schmid Dietrich von Schweinitz Roland Kappler

Cancers (Basel) 2020 Aug 15;12(8). Epub 2020 Aug 15.

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University, 80337 Munich, Germany.

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August 2020

High expression of IGF2-derived intronic miR-483 predicts outcome in hepatoblastoma.

Authors:
Jakob Benjamin Wilhelm Weiss Alexandra Elisabeth Wagner Corinna Eberherr Beate Häberle Christian Vokuhl Dietrich von Schweinitz Roland Kappler

Cancer Biomark 2020 ;28(3):321-328

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Munich, Germany.

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January 2020

Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications.

Authors:
Juan Carrillo-Reixach Laura Torrens Marina Simon-Coma Laura Royo Montserrat Domingo-Sàbat Jordi Abril-Fornaguera Nicholas Akers Margarita Sala Sonia Ragull Magdalena Arnal Núria Villalmanzo Stefano Cairo Alberto Villanueva Roland Kappler Marta Garrido Laura Guerra Constantino Sábado Gabriela Guillén Mar Mallo David Piñeyro María Vázquez-Vitali Olga Kuchuk María Elena Mateos Gema Ramírez Manuel López Santamaría Yasmina Mozo Aroa Soriano Michael Grotzer Sophie Branchereau Nagore García de Andoin Blanca López-Ibor Ricardo López-Almaraz José Antonio Salinas Bárbara Torres Francisco Hernández José Javier Uriz Monique Fabre Julià Blanco Claudia Paris Viera Bajčiová Geneviève Laureys Helena Masnou Ariadna Clos Cristina Belendez Catherine Guettier Lauro Sumoy Ramón Planas Mireia Jordà Lara Nonell Piotr Czauderna Bruce Morland Daniela Sia Bojan Losic Marie Annick Buendia Maria Rosa Sarrias Josep M Llovet Carolina Armengol

J Hepatol 2020 Aug 30;73(2):328-341. Epub 2020 Mar 30.

Childhood Liver Oncology Group, Germans Trias i Pujol Research Institute (IGTP), Program for Predictive and Personalized Medicine of Cancer (PMPPC), Badalona, Spain; CIBER, Hepatic and Digestive Diseases, Barcelona, Spain. Electronic address:

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August 2020

Downregulation of SFRP1 is a protumorigenic event in hepatoblastoma and correlates with beta-catenin mutations.

Authors:
Ivonne Regel Melanie Eichenmüller Ujjwal Mukund Mahajan Beate Hagl Simone Benitz Beate Häberle Christian Vokuhl Dietrich von Schweinitz Roland Kappler

J Cancer Res Clin Oncol 2020 May 18;146(5):1153-1167. Epub 2020 Mar 18.

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, LMU Munich, Lindwurmstr. 2a, 80337, Munich, Germany.

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May 2020

Lymphatic Leakage after Surgery for Neuroblastoma: A Rare Complication?

Authors:
Alexandra Froeba-Pohl Jakob Muehling Katharina Vill Veit Grote Tim Komm Dorothee Seitz Roland Kappler Dietrich von Schweinitz

Eur J Pediatr Surg 2020 Jan 20. Epub 2020 Jan 20.

Department of Pediatric Surgery, Munich University Hospital Dr von Hauner Children's Hospital, Munchen, Germany.

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January 2020

Vessel adherent growth represents a major challenge in the surgical resection of neuroblastoma and Is associated with adverse outcome.

Authors:
Jakob Mühling Corinna Eberherr Josef Müller Höcker Veit Grote Dietrich von Schweinitz Roland Kappler Alexandra Fröba-Pohl

J Pediatr Surg 2019 Nov 23;54(11):2336-2342. Epub 2019 Jul 23.

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Germany.

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November 2019

Activation of Hedgehog Signaling in Aggressive Hepatic Hemangioma in Newborns and Infants.

Authors:
Danielle Wendling-Keim Christian Vokuhl Christoph Walz Lynn Rieder Rainer Grantzow Dietrich VON Schweinitz Roland Kappler Michael Berger

Anticancer Res 2019 May;39(5):2351-2360

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.

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May 2019

Targeting excessive MYCN expression using MLN8237 and JQ1 impairs the growth of hepatoblastoma cells.

Authors:
Corinna Eberherr Alexander Beck Christian Vokuhl Kristina Becker Beate Häberle Dietrich Von Schweinitz Roland Kappler

Int J Oncol 2019 May 5;54(5):1853-1863. Epub 2019 Mar 5.

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, D‑80337 Munich, Germany.

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May 2019

Author Correction: The landscape of genomic alterations across childhood cancers.

Authors:
Susanne N Gröbner Barbara C Worst Joachim Weischenfeldt Ivo Buchhalter Kortine Kleinheinz Vasilisa A Rudneva Pascal D Johann Gnana Prakash Balasubramanian Maia Segura-Wang Sebastian Brabetz Sebastian Bender Barbara Hutter Dominik Sturm Elke Pfaff Daniel Hübschmann Gideon Zipprich Michael Heinold Jürgen Eils Christian Lawerenz Serap Erkek Sander Lambo Sebastian Waszak Claudia Blattmann Arndt Borkhardt Michaela Kuhlen Angelika Eggert Simone Fulda Manfred Gessler Jenny Wegert Roland Kappler Daniel Baumhoer Stefan Burdach Renate Kirschner-Schwabe Udo Kontny Andreas E Kulozik Dietmar Lohmann Simone Hettmer Cornelia Eckert Stefan Bielack Michaela Nathrath Charlotte Niemeyer Günther H Richter Johannes Schulte Reiner Siebert Frank Westermann Jan J Molenaar Gilles Vassal Hendrik Witt Birgit Burkhardt Christian P Kratz Olaf Witt Cornelis M van Tilburg Christof M Kramm Gudrun Fleischhack Uta Dirksen Stefan Rutkowski Michael Frühwald Katja von Hoff Stephan Wolf Thomas Klingebiel Ewa Koscielniak Pablo Landgraf Jan Koster Adam C Resnick Jinghui Zhang Yanling Liu Xin Zhou Angela J Waanders Danny A Zwijnenburg Pichai Raman Benedikt Brors Ursula D Weber Paul A Northcott Kristian W Pajtler Marcel Kool Rosario M Piro Jan O Korbel Matthias Schlesner Roland Eils David T W Jones Peter Lichter Lukas Chavez Marc Zapatka Stefan M Pfister

Nature 2018 07;559(7714):E10

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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July 2018

Overexpression of promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma.

Authors:
Alexander Beck Franziska Trippel Alexandra Wagner Saskia Joppien Max Felle Christian Vokuhl Thomas Schwarzmayr Tim M Strom Dietrich von Schweinitz Gernot Längst Roland Kappler

Clin Epigenetics 2018 2;10:27. Epub 2018 Mar 2.

1Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Lindwurmstr. 2a, 80337 Munich, Germany.

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February 2019

The landscape of genomic alterations across childhood cancers.

Authors:
Susanne N Gröbner Barbara C Worst Joachim Weischenfeldt Ivo Buchhalter Kortine Kleinheinz Vasilisa A Rudneva Pascal D Johann Gnana Prakash Balasubramanian Maia Segura-Wang Sebastian Brabetz Sebastian Bender Barbara Hutter Dominik Sturm Elke Pfaff Daniel Hübschmann Gideon Zipprich Michael Heinold Jürgen Eils Christian Lawerenz Serap Erkek Sander Lambo Sebastian Waszak Claudia Blattmann Arndt Borkhardt Michaela Kuhlen Angelika Eggert Simone Fulda Manfred Gessler Jenny Wegert Roland Kappler Daniel Baumhoer Stefan Burdach Renate Kirschner-Schwabe Udo Kontny Andreas E Kulozik Dietmar Lohmann Simone Hettmer Cornelia Eckert Stefan Bielack Michaela Nathrath Charlotte Niemeyer Günther H Richter Johannes Schulte Reiner Siebert Frank Westermann Jan J Molenaar Gilles Vassal Hendrik Witt Birgit Burkhardt Christian P Kratz Olaf Witt Cornelis M van Tilburg Christof M Kramm Gudrun Fleischhack Uta Dirksen Stefan Rutkowski Michael Frühwald Katja von Hoff Stephan Wolf Thomas Klingebiel Ewa Koscielniak Pablo Landgraf Jan Koster Adam C Resnick Jinghui Zhang Yanling Liu Xin Zhou Angela J Waanders Danny A Zwijnenburg Pichai Raman Benedikt Brors Ursula D Weber Paul A Northcott Kristian W Pajtler Marcel Kool Rosario M Piro Jan O Korbel Matthias Schlesner Roland Eils David T W Jones Peter Lichter Lukas Chavez Marc Zapatka Stefan M Pfister

Nature 2018 03 28;555(7696):321-327. Epub 2018 Feb 28.

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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March 2018

MiR-492 regulates metastatic properties of hepatoblastoma via CD44.

Authors:
Julia von Frowein Stefanie M Hauck Roland Kappler Philipp Pagel Katrin K Fleischmann Thomas Magg Stefano Cairo Adelbert Roscher Dietrich von Schweinitz Irene Schmid

Liver Int 2018 07 25;38(7):1280-1291. Epub 2018 Jan 25.

Department of Pediatric Hematology and Oncology, Children's Research Center, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.

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July 2018

Expression of Truncated Neurokinin-1 Receptor in Childhood Neuroblastoma is Independent of Tumor Biology and Stage.

Authors:
Alexandra Pohl Roland Kappler Jakob Mühling Dietrich VON Schweinitz Michael Berger

Anticancer Res 2017 11;37(11):6079-6085

Department of Pediatric Surgery, Dr von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany

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November 2017

Transcriptional activation of Hedgehog pathway components in aggressive haemangioma.

Authors:
Danielle S Wendling-Keim Lynn Wanie Dietrich von Schweinitz Rainer Grantzow Roland Kappler

Exp Dermatol 2017 10 15;26(10):934-939. Epub 2017 Aug 15.

Department of Pediatric Surgery, Dr. von Hauner Childrens' Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.

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October 2017

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.

Authors:
Tim Ripperger Stefan S Bielack Arndt Borkhardt Ines B Brecht Birgit Burkhardt Gabriele Calaminus Klaus-Michael Debatin Hedwig Deubzer Uta Dirksen Cornelia Eckert Angelika Eggert Miriam Erlacher Gudrun Fleischhack Michael C Frühwald Astrid Gnekow Gudrun Goehring Norbert Graf Helmut Hanenberg Julia Hauer Barbara Hero Simone Hettmer Katja von Hoff Martin Horstmann Juliane Hoyer Thomas Illig Peter Kaatsch Roland Kappler Kornelius Kerl Thomas Klingebiel Udo Kontny Uwe Kordes Dieter Körholz Ewa Koscielniak Christof M Kramm Michaela Kuhlen Andreas E Kulozik Britta Lamottke Ivo Leuschner Dietmar R Lohmann Andrea Meinhardt Markus Metzler Lüder H Meyer Olga Moser Michaela Nathrath Charlotte M Niemeyer Rainer Nustede Kristian W Pajtler Claudia Paret Mareike Rasche Dirk Reinhardt Olaf Rieß Alexandra Russo Stefan Rutkowski Brigitte Schlegelberger Dominik Schneider Reinhard Schneppenheim Martin Schrappe Christopher Schroeder Dietrich von Schweinitz Thorsten Simon Monika Sparber-Sauer Claudia Spix Martin Stanulla Doris Steinemann Brigitte Strahm Petra Temming Kathrin Thomay Andre O von Bueren Peter Vorwerk Olaf Witt Marcin Wlodarski Willy Wössmann Martin Zenker Stefanie Zimmermann Stefan M Pfister Christian P Kratz

Am J Med Genet A 2017 Apr 7;173(4):1017-1037. Epub 2017 Feb 7.

Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.

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April 2017

Therapeutic Innovations for Targeting Hepatoblastoma.

Authors:
Agnès Garnier Matthias Ilmer Roland Kappler Michael Berger

Anticancer Res 2016 11;36(11):5577-5592

Department of Pediatric Surgery, Research Laboratories, Dr. von Hauner Children's Hospital, Ludwig Maximilians University Munich, Munich, Germany

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November 2016

Association of expression with tumor histology and prognosis in Wilms tumor: Potential for a new prognostic marker.

Authors:
Nadja Apelt Jochen Hubertus Doris Mayr Norbert Graf Rhoikos Furtwängler Dietrich Von Schweinitz Roland Kappler

Oncol Lett 2016 Oct 5;12(4):2854-2859. Epub 2016 Aug 5.

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig Maximilian University of Munich, Munich, 80337 Bavaria, Germany.

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October 2016

Activation of the Wnt/β-catenin pathway is common in wilms tumor, but rarely through β-catenin mutation and APC promoter methylation.

Authors:
Amei Schweigert Carmen Fischer Doris Mayr Dietrich von Schweinitz Roland Kappler Jochen Hubertus

Pediatr Surg Int 2016 Dec 27;32(12):1141-1146. Epub 2016 Sep 27.

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University, Lindwurmstr. 4, 80337, Munich, Germany.

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December 2016