Publications by authors named "Rola Husain"

5 Publications

  • Page 1 of 1

MRI Evaluation of Various Elbow, Forearm, and Wrist Neuropathies: A Pictorial Review.

Semin Musculoskelet Radiol 2021 Aug 27;25(4):617-627. Epub 2021 Oct 27.

Department of Radiology, Icahn School of Medicine at Mount Sinai Hospital, New York, New York.

Upper extremity entrapment neuropathies are common and can cause pain, sensory loss, and muscle weakness leading to functional disability. We conducted a retrospective review from January 2007 until March 2020 of the magnetic resonance imaging (MRI) features of intrinsic and extrinsic causes of wrist, forearm, and elbow neuropathies of 637 patients who received a diagnosis of neuropathy by means of clinical and electrodiagnostic testing. We discuss cases with varying intrinsic and extrinsic nerve pathologies, including postoperative examples, affecting the median, radial, and ulnar nerve.Our collection of cases demonstrates a diversity of intrinsic and extrinsic causative factors. Intrinsic pathologies include neuritis as well as tumors arising from the nerve. Extrinsic causes resulting in nerve entrapment include masses, acute and chronic posttraumatic cases, anatomical variants, inflammatory and crystal deposition, calcium pyrophosphate deposition disease, and dialysis-related amyloidosis. Finally, we review postsurgical cases, such as carpal tunnel release and ulnar nerve transposition.Although upper extremity neuropathies tend to have a typical clinical presentation, imaging, particularly MRI, plays a vital role in evaluating the etiology and severity of each neuropathy and ultimately helps guide clinical management.
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http://dx.doi.org/10.1055/s-0041-1729961DOI Listing
August 2021

Epiphyseal Ewing Sarcoma in a skeletally mature patient: A case report and review of the literature.

Radiol Case Rep 2021 May 19;16(5):1191-1197. Epub 2021 Mar 19.

Diagnostic, Molecular and Interventional Radiology, Mount Sinai Health System, 1468 Madison Ave, New York, NY, 10029, USA.

While Ewing sarcoma of bone is the second most common primary osseous malignancy in childhood where it typically involves the diaphysis or metadiaphyses of long bones of skeletally immature patients, primary epiphyseal involvement of the long bone in skeletally mature patients is rare with no cases reported in the literature to our knowledge, rendering this case the first of its kind. We present the first case of primary Ewing Sarcoma of the epiphyses of the long bones in a skeletally mature 20-year-old male patient. The patient initially presented with left knee stiffness and pain that was empirically treated with non-steroidal anti-inflammatory medications. His pain progressed despite treatment. An x-ray of the left knee was obtained 5 months later demonstrating an irregular lucent lesion in the medial femoral condyle. A subsequent MRI revealed an enhancing lesion in the medial femoral condyle, and when biopsied it was consistent with Ewing sarcoma (positive for gene rearrangement by fluorescence in situ hybridization). The lesion was resected surgically, and the patient underwent neoadjuvant chemotherapy with a good clinical outcome.
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http://dx.doi.org/10.1016/j.radcr.2021.02.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010574PMC
May 2021

Spontaneous osteonecrosis of the knee (SONK): The role of MR imaging in predicting clinical outcome.

J Orthop 2020 Nov-Dec;22:606-611. Epub 2020 Nov 19.

Diagnostic, Molecular and Interventional Radiology, Mount Sinai Health System, New York, NY, USA.

Background/aim: We try to investigate the association between patterns of imaging findings in patients who had a diagnosis of subchondral fracture around the knee, formerly known as SONK and their clinical outcome.

Materials And Methods: We retrospectively identified 43 knees of 37 patients (28 males, 15 females) who had diagnosis of subchondral fractures around the knee. The mean age is 56-year-old (range 17-83). Musculoskeletal fellowship trained radiologist evaluated all 43 knee MRI in: 1)location of marrow edema 2)peri-osseous edema; 3) subchondral fracture line; 4) subchondral articular surface contour; 5)meniscal tear and extrusion; 6)adjacent soft tissue edema; 7) joint effusion. Independent clinical chart review was performed for clinical outcome with follow up time average of 13.3 months (range 0-88 months). Bad outcome was defined as worsening on imaging, continued complaint with surgical management and knee replacement or another episode of SONK. Chi-square analysis and Student's T tests were conducted to test the statistical significance of association between MR findings and outcomes. Statistical significance was set at p = 0.05 level.

Results: Of 43 knees, 6 patients had another episodes of SONK (14%), 11 patients were not improving or needed injection vs arthroscopy (26%), 4 patients required arthroplasty (9%), 22 patients had no negative outcome (51%). Gender, age, diabetic status, and location of the subchondral fracture show no influence on outcome. Worse outcome group had a significantly higher average BMI (31.7 vs. 28.0, P = 0.02). Positive change of subchondral articular surface contour is the only imaging finding with positive association with worse outcome (80% vs. 39.9%, P = 0.02). Presence of positive findings of above 3), 4), 5) and 6) had higher percentage of bad outcome (77.8%) compared to those with less positive findings (47.2%).

Conclusion: MR imaging findings may help at identifying SONK patient with potential risk of developing bad outcome.
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http://dx.doi.org/10.1016/j.jor.2020.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718131PMC
November 2020

MRI features of pyoderma gangrenosum in a diabetic patient with ulcerative colitis: A case report and review of the literature.

Radiol Case Rep 2020 Dec 6;15(12):2540-2546. Epub 2020 Oct 6.

Diagnostic, Molecular and Interventional Radiology, Mount Sinai Health System, 1468 Madison Ave, New York, NY 10029, USA.

Pyoderma gangrenosum (PG) is a rare noninfectious skin condition which clinical picture can overlap with that of the diabetic foot. Meticulous physical examination along with biopsy and magnetic resonance imaging (MRI) can make the distinction easier, saving the patients from undergoing a debilitating intervention. We report a case of pathologically proven PG in the right ankle region of a 55-year old male with known uncontrolled diabetes mellitus and inflammatory bowel disease. Radiographs revealed increased soft tissue density overlying the lateral melleolus of the right ankle. MRI showed a well-defined soft tissue mass with heterogeneously intrinsically high signal intensity on T1- and on T2-weighted images, and heterogeneous peripheral enhancement on fat-suppressed, contrast-enhanced T1-weighted images. Histologically, diffuse neutrophilic infiltrate throughout the dermis was present without micro-organisms. This is the first report of MRI findings of PG in the ankle. We also summarize the findings of previously reported cases of PG.
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http://dx.doi.org/10.1016/j.radcr.2020.09.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7548426PMC
December 2020

Rhabdomyolysis as a manifestation of a severe case of COVID-19: A case report.

Radiol Case Rep 2020 Sep 7;15(9):1633-1637. Epub 2020 Jul 7.

Diagnostic, Molecular and Interventional Radiology, Mount Sinai Health System, 1468 Madison Ave, 10029, New York, NY, USA.

Since the outbreak of the ongoing pandemic of the novel coronavirus disease (COVID-19) in Wuhan, China, from December 2019, we have learned that multiple organs can be affected with the potential for various complications. Although myalgia is a frequent symptom in COVID-19 patients, no imaging findings of rhabdomyolysis have been featured in the literature. We report a case of presumed rhabdomyolysis in a 38-year-old male with COVID-19 based on the clinical presentation, laboratory results and radiological findings. By discussing the diagnostic rationale and reviewing the relevant literature we hope to advance the existing understanding of this disease and its effects on the musculoskeletal system.
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http://dx.doi.org/10.1016/j.radcr.2020.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340044PMC
September 2020
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