Publications by authors named "Rohayu Hami"

5 Publications

  • Page 1 of 1

Knowledge, Awareness, Attitude and Preventive Behaviour on the Transmission of the Pandemic Novel Coronavirus Among Malaysians.

Malays J Med Sci 2021 Apr 21;28(2):106-118. Epub 2021 Apr 21.

Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Pulau Pinang, Malaysia.

Background: Restricted movement and preventive actions have been introduced to break the chain of transmission of a new coronavirus. This study was conducted to determine the level of knowledge, awareness, attitude and preventive behaviour regarding the transmission of the COVID-19.

Methods: A cross-sectional study was conducted among Malaysians aged 20 years old and over, who had accessed the internet and used the WhatsApp application. The sampling method was a convenient snowball from 14 Malaysian states. This study was conducted online using questionnaires during the Movement Control Order due to the pandemic.

Results: Approximately 40.0%, 46.1% and 47.4% of 1,290 participants had a score above the median (good score) for preventive behaviour, attitude and knowledge, respectively. Age was significantly associated with poor knowledge (adjusted odds ratio [AOR] 0.98; 95% confidence interval [CI]: 0.97, 0.99; = 0.026). Males (AOR 1.35; 95% CI: 1.05, 1.74; = 0.021), Malays (AOR 1.41; 95% CI: 1.01, 1.98; = 0.043) and Chinese (AOR 2.19; 95% CI: 1.17, 4.13; = 0.015) were the associated factors for poor attitude. Chinese ethnicity was significantly associated with poor preventive behaviour (AOR 2.80; 95% CI: 1.39, 5.61; = 0.004).

Conclusion: The level of knowledge, attitude and practices were high except for a few questions. The young, males and Malay and Chinese individuals need health education.
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http://dx.doi.org/10.21315/mjms2021.28.2.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075592PMC
April 2021

Multicentre prospective cohort study of unmet supportive care needs among patients with breast cancer throughout their cancer treatment trajectory in Penang: a PenBCNeeds Study protocol.

BMJ Open 2021 03 15;11(3):e044746. Epub 2021 Mar 15.

Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Penang, Malaysia.

Introduction: Proper assessment of unmet supportive care needs of patients with breast cancer and its influencing factors at different treatment intervals will improve the rehabilitation of patients with breast cancer. Therefore, this study aims to determine the prevalence of unmet supportive care needs, changes of needs over time and associated factors during the treatment period.

Methods And Analysis: This multicentre, prospective cohort study will be conducted in three governmental hospitals and one tertiary cancer institute in Penang, Malaysia. Adult women diagnosed with primary or recurrent tumour, node, metastases stage I-IV breast cancer based on pathological biopsy will be eligible for this study. At least 281 samples are required for this study. Participants will undergo follow-up at three time intervals: T1 at breast cancer diagnosis; T2 at 3 months after diagnosis and T3 at 6 months after diagnosis. Patients will complete a set of questionnaires at each time. The primary outcome of this study includes the changes in supportive care needs over three time points, followed by the secondary outcome examining patients' characteristics, coping behaviours and positive psychological components as they affect changes in unmet supportive care needs over time.

Ethics And Dissemination: The study has received ethics approval from the Medical Research and Ethics Committee, Ministry of Health Malaysia (NMRR-19-268-45809 IIR) and the Human Research Ethics Committee of Universiti Sains Malaysia (USM/JEPeM/17100443). The results of the prospective study will be submitted for publication in a peer-reviewed journal.
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http://dx.doi.org/10.1136/bmjopen-2020-044746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959240PMC
March 2021

Depression and anxiety in the Malaysian urban population and their association with demographic characteristics, quality of life, and the emergence of the COVID-19 pandemic.

Curr Psychol 2021 Feb 19:1-12. Epub 2021 Feb 19.

Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200 Kepala Batas, Pulau Pinang Malaysia.

The prevalence of depression and anxiety has been shown to be higher in the urban population compared with the rural population. The present study investigated the prevalence of depression symptoms, anxiety symptoms, and depression with comorbid anxiety symptoms and their associated factors in a random sample drawn from several urban communities in Malaysia. This study also determined the association between the emergence of the COVID-19 pandemic and depression symptoms, anxiety symptoms, and depression with comorbid anxiety symptoms. We recruited 326 participants, who were administered a sociodemographic characteristics questionnaire; the 21-item Depression, Anxiety, and Stress Scale (DASS-21) to assess the presence or absence of depression symptoms, anxiety symptoms, and depression with comorbid anxiety symptoms; and the World Health Organization Quality of Life-BREF (WHOQoL-BREF) to assess their QoL. The following prevalence values were obtained among the participants: depression symptoms, 23.9%; anxiety symptoms, 41.7%; and depression with comorbid anxiety symptoms, 19.9%. Those assessed after the declaration of COVID-19 as a global pandemic showed increased odds of depressive symptoms (adjusted OR = 2.99, 95% CI = 1.41-6.35,  = 0.006) and depressive with comorbid anxiety symptoms (adjusted OR = 3.19, 95% CI = 1.37-7.45,  = 0.005), while the presence of comorbid stress increased the odds of depressive symptoms (adjusted OR = 16.00, 95% CI = 7.84-32.63,  < 0.001), anxiety symptoms (adjusted OR = 19.72, 95% CI = 9.75-39.89,  < 0.001), and depressive with comorbid anxiety symptoms (adjusted OR = 40.44, 95% CI = 15.90-102.87,  < 0.001). Higher psychological QoL reduced the odds of depressive symptoms (adjusted OR = 0.83, 95% CI = 0.69-0.99,  = 0.032) and depressive with comorbid anxiety symptoms (adjusted OR = 0.82, 95% CI = 0.68-0.98,  = 0.041), whereas higher physical health QoL (adjusted OR = 0.85, 95% CI = 0.75-0.97,  = 0.021) and social relationship QoL (adjusted OR = 0.70, 95% CI = 0.55-0.90,  = 0.009) reduced the odds of anxiety symptoms. Based on our findings, we recommended several measures to curb psychological complications among the urban population, particularly as the battle to contain COVID-19 is ongoing.
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http://dx.doi.org/10.1007/s12144-021-01492-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7892323PMC
February 2021

A narrative review of brain-derived neurotrophic factor (BDNF) on cognitive performance in Alzheimer's disease.

Growth Factors 2020 Jun-Jul;38(3-4):210-225. Epub 2021 Jan 11.

Institut Perubatan dan Pengigian Termaju, Lifestyle Science Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Malaysia.

Brain-derived neurotrophic factor (BDNF) is a neurotrophin that is highly expressed in the brain. It influences neuronal survival, growth and acts as a control centre for neurotransmitters. It also plays a crucial role in learning and memory. Current evidence indicates that BDNF may be a possible neurotrophic factor that controls cognitive functions under normal and neuropathological conditions. Recent findings indicate a reduction in cognitive performance in individuals with Alzheimer's disease (AD). This relationship between cognitive performance and AD is important for investigating both the time they overlap and the pathophysiological mechanism in each case. Therefore, this study reviewed the existing knowledge about BDNF and cognitive performance in the AD population. The findings support the idea that this tropic factor may be a potential biomarker for evaluating the changes in cognitive performance in AD.
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http://dx.doi.org/10.1080/08977194.2020.1864347DOI Listing
January 2021

Diagnosis of cancer is not a death sentence: Examining posttraumatic growth and its associated factors in cancer patients.

J Psychosoc Oncol 2019 Sep-Oct;37(5):636-651. Epub 2019 Mar 1.

Lifestyle Science Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia , Kepala Batas , Pulau Pinang , Malaysia.

Posttraumatic growth (PTG) is the experience of positive psychological growth as a result of struggle with highly challenging life crises. This study was conducted to investigate the degree of PTG and its associated factors, as well as to identify which positive psychological parameters most significantly associated with greater PTG among Malaysian cancer patients. This cross-sectional survey included 195 patients with different cancer diagnoses. Perceived spousal support, level of hope, level of optimism, and PTG were measured using various validated indexes. The total mean score for PTG Inventory-Short Form (PTGI-SF) was 39.87 (±9.09). Female gender, Islamic religious belief, and having higher level of hope and greater spousal support were associated with a higher PTGI-SF score, and the most significant predictor was the hope scale. Malaysian cancer patients exhibited a high level of PTG, and hope was the positive psychological factor which was most significantly associated with PTG. Psychosocial interventions that promote positive psychology should be included in the treatment for cancer patients.
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http://dx.doi.org/10.1080/07347332.2019.1574946DOI Listing
February 2020