Roger W Chapman

Roger W Chapman

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Roger W Chapman

Roger W Chapman

Publications by authors named "Roger W Chapman"

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Pre-clinical development of U3-1784, a novel FGFR4 antibody against cancer, and avoidance of its on-target toxicity.

Authors:
René Bartz Keisuke Fukuchi Toshiaki Ohtsuka Tanja Lange Katrin Gruner Ichiro Watanabe Shinko Hayashi Yoko Oda Reimi Kawaida Hironobu Komori Yoshinori Kashimoto Peter Wirtz Jan-Peter A Mayer Mauricio Redondo-Müller Shuntaro Saito Mizuki Takahashi Hiroyuki Hanzawa Emi Imai Alberto Martinez Masaharu Hanai Dieter Häussinger Roger W Chapman Toshinori Agatsuma Johannes Bange Reimar Abraham

Mol Cancer Ther 2019 Jul 26. Epub 2019 Jul 26.

Antibody Development, Lead Discovery Center GmbH

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http://dx.doi.org/10.1158/1535-7163.MCT-18-0048DOI Listing
July 2019

Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System.

Authors:
Elizabeth C Goode Allan B Clark George F Mells Brijesh Srivastava Kelly Spiess William T H Gelson Palak J Trivedi Kate D Lynch Edit Castren Mette N Vesterhus Tom H Karlsen Sun-Gou Ji Carl A Anderson Douglas Thorburn Mark Hudson Michael A Heneghan Mark A Aldersley Andrew Bathgate Richard N Sandford Graeme J Alexander Roger W Chapman Martine Walmsley Gideon M Hirschfield Simon M Rushbrook

Hepatology 2019 May 4;69(5):2120-2135. Epub 2019 Mar 4.

Norfolk and Norwich University Hospital, Norwich, United Kingdom.

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http://dx.doi.org/10.1002/hep.30479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519245PMC
May 2019

Effects of Vedolizumab in Patients with Primary Sclerosing Cholangitis and Inflammatory Bowel Diseases.

Authors:
Kate D Lynch Roger W Chapman Satish Keshav Aldo J Montano-Loza Andrew L Mason Andreas E Kremer Marcel Vetter Manon de Krijger Cyriel Y Ponsioen Palak Trivedi Gideon Hirschfield Christoph Schramm Chung Heng Liu Christopher L Bowlus Derek J Estes Daniel Pratt Charlotte Hedin Annika Bergquist Annemarie C de Vries C Janneke van der Woude Lei Yu David N Assis James Boyer Henriette Ytting Emina Hallibasic Michael Trauner Hanns-Ulrich Marschall Luigi M Daretti Marco Marzioni Kidist K Yimam Nicola Perin Annarosa Floreani Benedetta Terziroli Beretta-Piccoli Jennifer K Rogers Cynthia Levy

Clin Gastroenterol Hepatol 2019 May 14. Epub 2019 May 14.

Division of Hepatology, University of Miami, Miami, Florida. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2019.05.013DOI Listing
May 2019

The Use of Biologics in Patients with Inflammatory Bowel Disease and Primary Sclerosing Cholangitis.

Authors:
Kate D Lynch Satish Keshav Roger W Chapman

Curr Hepatol Rep 2019 7;18(1):115-126. Epub 2019 Mar 7.

Translational Gastroenterology Unit, Nuffield Department of Medicine, Level 5, John Radcliffe Hospital, University of Oxford, Headley Way, Headington, Oxford, OX3 9DU UK.

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http://dx.doi.org/10.1007/s11901-019-00456-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445403PMC
March 2019

Evolving role of magnetic resonance techniques in primary sclerosing cholangitis.

Authors:
Emmanuel A Selvaraj Emma L Culver Helen Bungay Adam Bailey Roger W Chapman Michael Pavlides

World J Gastroenterol 2019 Feb;25(6):644-658

Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom.

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http://dx.doi.org/10.3748/wjg.v25.i6.644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378540PMC
February 2019

A novel prognostic model for transplant-free survival in primary sclerosing cholangitis.

Authors:
Elisabeth M de Vries Junfeng Wang Kate D Williamson Mariska M Leeflang Kirsten Boonstra Rinse K Weersma Ulrich Beuers Roger W Chapman Ronald B Geskus Cyriel Y Ponsioen

Gut 2018 10 24;67(10):1864-1869. Epub 2017 Jul 24.

Department of Gastroenterology & Hepatology, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/gutjnl-2016-313681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145288PMC
October 2018

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.

Authors:
Rudi Alberts Elisabeth M G de Vries Elizabeth C Goode Xiaojun Jiang Fotis Sampaziotis Krista Rombouts Katrin Böttcher Trine Folseraas Tobias J Weismüller Andrew L Mason Weiwei Wang Graeme Alexander Domenico Alvaro Annika Bergquist Niklas K Björkström Ulrich Beuers Einar Björnsson Kirsten Muri Boberg Christopher L Bowlus Maria C Bragazzi Marco Carbone Olivier Chazouillères Angela Cheung Georgios Dalekos John Eaton Bertus Eksteen David Ellinghaus Martti Färkkilä Eleonora A M Festen Annarosa Floreani Irene Franceschet Daniel Nils Gotthardt Gideon M Hirschfield Bart van Hoek Kristian Holm Simon Hohenester Johannes Roksund Hov Floris Imhann Pietro Invernizzi Brian D Juran Henrike Lenzen Wolfgang Lieb Jimmy Z Liu Hanns-Ulrich Marschall Marco Marzioni Espen Melum Piotr Milkiewicz Tobias Müller Albert Pares Christian Rupp Christian Rust Richard N Sandford Christoph Schramm Stefan Schreiber Erik Schrumpf Mark S Silverberg Brijesh Srivastava Martina Sterneck Andreas Teufel Ludovic Vallier Joanne Verheij Arnau Vich Vila Boudewijn de Vries Kalliopi Zachou Roger W Chapman Michael P Manns Massimo Pinzani Simon M Rushbrook Konstantinos N Lazaridis Andre Franke Carl A Anderson Tom H Karlsen Cyriel Y Ponsioen Rinse K Weersma

Gut 2018 08 4;67(8):1517-1524. Epub 2017 Aug 4.

Department of Gastroenterology and Hepatology, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1136/gutjnl-2016-313598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797498PMC
August 2018

Cost effectiveness of using ursodeoxycholic acid to treat primary biliary cholangitis.

Authors:
Roger W Chapman

Br J Hosp Med (Lond) 2018 Aug;79(8):460-464

Emeritus Consultant in Hepatology, Nuffield Department of Medicine, Oxford University and Translational Gastroenterology Unit, Oxford University Hospital, Oxford OX3 9DU.

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http://dx.doi.org/10.12968/hmed.2018.79.8.460DOI Listing
August 2018

NI-0801, an anti-chemokine (C-X-C motif) ligand 10 antibody, in patients with primary biliary cholangitis and an incomplete response to ursodeoxycholic acid.

Authors:
Kathy L de Graaf Geneviève Lapeyre Florence Guilhot Walter Ferlin Stuart M Curbishley Marco Carbone Paul Richardson Sulleman Moreea C Anne McCune Stephen D Ryder Roger W Chapman Annarosa Floreani David E Jones Cristina de Min David H Adams Pietro Invernizzi

Hepatol Commun 2018 May 23;2(5):492-503. Epub 2018 Mar 23.

Division of Gastroenterology and Program for Autoimmune Liver Diseases, International Center for Digestive Health, Department of Medicine and Surgery University of Milan-Bicocca Milan Italy.

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http://dx.doi.org/10.1002/hep4.1170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944576PMC
May 2018

Th1 and Innate Lymphoid Cells Accumulate in Primary Sclerosing Cholangitis-associated Inflammatory Bowel Disease.

Authors:
Agnes Gwela Priya Siddhanathi Roger W Chapman Simon Travis Fiona Powrie Carolina V Arancibia-Cárcamo Alessandra Geremia

J Crohns Colitis 2017 Sep;11(9):1124-1134

Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/ecco-jcc/jjx050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637950PMC
September 2017

Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis.

Authors:
Tobias J Weismüller Palak J Trivedi Annika Bergquist Mohamad Imam Henrike Lenzen Cyriel Y Ponsioen Kristian Holm Daniel Gotthardt Martti A Färkkilä Hanns-Ulrich Marschall Douglas Thorburn Rinse K Weersma Johan Fevery Tobias Mueller Olivier Chazouillères Kornelius Schulze Konstantinos N Lazaridis Sven Almer Stephen P Pereira Cynthia Levy Andrew Mason Sigrid Naess Christopher L Bowlus Annarosa Floreani Emina Halilbasic Kidist K Yimam Piotr Milkiewicz Ulrich Beuers Dep K Huynh Albert Pares Christine N Manser George N Dalekos Bertus Eksteen Pietro Invernizzi Christoph P Berg Gabi I Kirchner Christoph Sarrazin Vincent Zimmer Luca Fabris Felix Braun Marco Marzioni Brian D Juran Karouk Said Christian Rupp Kalle Jokelainen Maria Benito de Valle Francesca Saffioti Angela Cheung Michael Trauner Christoph Schramm Roger W Chapman Tom H Karlsen Erik Schrumpf Christian P Strassburg Michael P Manns Keith D Lindor Gideon M Hirschfield Bettina E Hansen Kirsten M Boberg

Gastroenterology 2017 06 6;152(8):1975-1984.e8. Epub 2017 Mar 6.

Norwegian PSC Research Center and Section for Gastroenterology, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.02.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546611PMC
June 2017

Update on primary sclerosing cholangitis.

Authors:
Roger W Chapman

Clin Liver Dis (Hoboken) 2017 May 26;9(5):107-110. Epub 2017 May 26.

Nuffield Department of Medicine Oxford University Oxford United Kingdom.

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http://dx.doi.org/10.1002/cld.633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467155PMC
May 2017

Are Dominant Strictures in Primary Sclerosing Cholangitis a Risk Factor for Cholangiocarcinoma?

Authors:
Roger W Chapman Kate D Williamson

Curr Hepatol Rep 2017 27;16(2):124-129. Epub 2017 Apr 27.

Nuffield Department of Medicine, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1007/s11901-017-0341-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486581PMC
April 2017

Validation of the prognostic value of histologic scoring systems in primary sclerosing cholangitis: An international cohort study.

Authors:
Elisabeth M G de Vries Manon de Krijger Martti Färkkilä Johanna Arola Peter Schirmacher Daniel Gotthardt Benjamin Goeppert Palak J Trivedi Gideon M Hirschfield Henriette Ytting Ben Vainer Henk R van Buuren Katharina Biermann Maren H Harms Olivier Chazouilleres Dominique Wendum Astrid D Kemgang Roger W Chapman Lai Mun Wang Kate D Williamson Annette S H Gouw Valerie Paradis Christine Sempoux Ulrich Beuers Stefan G Hübscher Joanne Verheij Cyriel Y Ponsioen

Hepatology 2017 03 11;65(3):907-919. Epub 2017 Jan 11.

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.28963DOI Listing
March 2017

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.

Authors:
Sun-Gou Ji Brian D Juran Sören Mucha Trine Folseraas Luke Jostins Espen Melum Natsuhiko Kumasaka Elizabeth J Atkinson Erik M Schlicht Jimmy Z Liu Tejas Shah Javier Gutierrez-Achury Kirsten M Boberg Annika Bergquist Severine Vermeire Bertus Eksteen Peter R Durie Martti Farkkila Tobias Müller Christoph Schramm Martina Sterneck Tobias J Weismüller Daniel N Gotthardt David Ellinghaus Felix Braun Andreas Teufel Mattias Laudes Wolfgang Lieb Gunnar Jacobs Ulrich Beuers Rinse K Weersma Cisca Wijmenga Hanns-Ulrich Marschall Piotr Milkiewicz Albert Pares Kimmo Kontula Olivier Chazouillères Pietro Invernizzi Elizabeth Goode Kelly Spiess Carmel Moore Jennifer Sambrook Willem H Ouwehand David J Roberts John Danesh Annarosa Floreani Aliya F Gulamhusein John E Eaton Stefan Schreiber Catalina Coltescu Christopher L Bowlus Velimir A Luketic Joseph A Odin Kapil B Chopra Kris V Kowdley Naga Chalasani Michael P Manns Brijesh Srivastava George Mells Richard N Sandford Graeme Alexander Daniel J Gaffney Roger W Chapman Gideon M Hirschfield Mariza de Andrade Simon M Rushbrook Andre Franke Tom H Karlsen Konstantinos N Lazaridis Carl A Anderson

Nat Genet 2017 Feb 19;49(2):269-273. Epub 2016 Dec 19.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.

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http://dx.doi.org/10.1038/ng.3745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540332PMC
February 2017

IgG4-related hepatobiliary disease: an overview.

Authors:
Emma L Culver Roger W Chapman

Nat Rev Gastroenterol Hepatol 2016 10 14;13(10):601-12. Epub 2016 Sep 14.

Translational Gastroenterology Unit, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK.

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http://dx.doi.org/10.1038/nrgastro.2016.132DOI Listing
October 2016

Immunoglobulin G4(+) B-cell receptor clones distinguish immunoglobulin G 4-related disease from primary sclerosing cholangitis and biliary/pancreatic malignancies.

Authors:
Marieke E Doorenspleet Lowiek M Hubers Emma L Culver Lucas J Maillette de Buy Wenniger Paul L Klarenbeek Roger W Chapman Frank Baas Stan F van de Graaf Joanne Verheij Thomas M van Gulik Eleanor Barnes Ulrich Beuers Niek de Vries

Hepatology 2016 08 8;64(2):501-7. Epub 2016 Jun 8.

Amsterdam Rheumatology and Immunology Center, Department of Clinical Immunology & Rheumatology, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hep.28568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017301PMC
August 2016

Elevated Serum IgG4 Levels in Diagnosis, Treatment Response, Organ Involvement, and Relapse in a Prospective IgG4-Related Disease UK Cohort.

Authors:
Emma L Culver Ross Sadler Dawn Simpson Tamsin Cargill Mateusz Makuch Adrian C Bateman Anthony J Ellis Jane Collier Roger W Chapman P Klenerman Eleanor Barnes Berne Ferry

Am J Gastroenterol 2016 05 19;111(5):733-43. Epub 2016 Apr 19.

Clinical Immunology Department, Churchill Hospital, Oxford, UK.

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http://dx.doi.org/10.1038/ajg.2016.40DOI Listing
May 2016

Surrogate endpoints for clinical trials in primary sclerosing cholangitis: Review and results from an International PSC Study Group consensus process.

Authors:
Cyriel Y Ponsioen Roger W Chapman Olivier Chazouillères Gideon M Hirschfield Tom H Karlsen Ansgar W Lohse Massimo Pinzani Erik Schrumpf Michael Trauner Gregory J Gores

Hepatology 2016 Apr 23;63(4):1357-67. Epub 2015 Dec 23.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1002/hep.28256DOI Listing
April 2016

New Thoughts on Immunoglobulin G4-Related Sclerosing Cholangitis.

Authors:
Wouter L Smit Emma L Culver Roger W Chapman

Clin Liver Dis 2016 Feb 6;20(1):47-65. Epub 2015 Oct 6.

Translational Gastroenterology Unit, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK; Nuffield Department of Medicine, University of Oxford, Old Road Campus, Oxford OX3 7BN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2015.08.004DOI Listing
February 2016

New Therapeutic Strategies for Primary Sclerosing Cholangitis.

Authors:
Kate D Williamson Roger W Chapman

Semin Liver Dis 2016 Feb 12;36(1):5-14. Epub 2016 Feb 12.

Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, United Kingdom.

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http://dx.doi.org/10.1055/s-0035-1571274DOI Listing
February 2016

Primary sclerosing cholangitis: a clinical update.

Authors:
Kate D Williamson Roger W Chapman

Br Med Bull 2015 Jun 16;114(1):53-64. Epub 2015 May 16.

Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, UK

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http://dx.doi.org/10.1093/bmb/ldv019DOI Listing
June 2015

Primary sclerosing cholangitis.

Authors:
Kate D Williamson Roger W Chapman

Dig Dis 2014 23;32(4):438-45. Epub 2014 Jun 23.

Nuffield Department of Medicine, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1159/000358150DOI Listing
February 2015

Serum immunoglobulin G4 and immunoglobulin G1 for distinguishing immunoglobulin G4-associated cholangitis from primary sclerosing cholangitis.

Authors:
Kirsten Boonstra Emma L Culver Lucas Maillette de Buy Wenniger Marianne J van Heerde Karel J van Erpecum Alexander C Poen Karin M J van Nieuwkerk B W Marcel Spanier Ben J M Witteman Hans A R E Tuynman Nan van Geloven Henk van Buuren Roger W Chapman Eleanor Barnes Ulrich Beuers Cyriel Y Ponsioen

Hepatology 2014 May 1;59(5):1954-63. Epub 2014 Apr 1.

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1002/hep.26977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489327PMC
May 2014

Malignancy in primary sclerosing cholangitis: Bile duct, liver, and colon.

Authors:
Roger W Chapman

Clin Liver Dis (Hoboken) 2014 Apr 28;3(4):83-85. Epub 2014 Apr 28.

Consultant Hepatologist Oxford University Hospitals Oxford UK.

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http://dx.doi.org/10.1002/cld.334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448705PMC
April 2014

The resurgence of serum alkaline phosphatase as a surrogate biomarker for prognosis in primary sclerosing cholangitis.

Authors:
Jayant A Talwalkar Roger W Chapman

Clin Gastroenterol Hepatol 2013 Jul 13;11(7):847-9. Epub 2013 Apr 13.

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http://dx.doi.org/10.1016/j.cgh.2013.03.029DOI Listing
July 2013

The genetics of complex cholestatic disorders.

Authors:
Gideon M Hirschfield Roger W Chapman Tom H Karlsen Frank Lammert Konstantinos N Lazaridis Andrew L Mason

Gastroenterology 2013 Jun 10;144(7):1357-74. Epub 2013 Apr 10.

Centre for Liver Research, National Institute for Health Research Biomedical Research Unit, University of Birmingham, Birmingham, England.

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http://dx.doi.org/10.1053/j.gastro.2013.03.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705954PMC
June 2013

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

Authors:
Jimmy Z Liu Johannes Roksund Hov Trine Folseraas Eva Ellinghaus Simon M Rushbrook Nadezhda T Doncheva Ole A Andreassen Rinse K Weersma Tobias J Weismüller Bertus Eksteen Pietro Invernizzi Gideon M Hirschfield Daniel Nils Gotthardt Albert Pares David Ellinghaus Tejas Shah Brian D Juran Piotr Milkiewicz Christian Rust Christoph Schramm Tobias Müller Brijesh Srivastava Georgios Dalekos Markus M Nöthen Stefan Herms Juliane Winkelmann Mitja Mitrovic Felix Braun Cyriel Y Ponsioen Peter J P Croucher Martina Sterneck Andreas Teufel Andrew L Mason Janna Saarela Virpi Leppa Ruslan Dorfman Domenico Alvaro Annarosa Floreani Suna Onengut-Gumuscu Stephen S Rich Wesley K Thompson Andrew J Schork Sigrid Næss Ingo Thomsen Gabriele Mayr Inke R König Kristian Hveem Isabelle Cleynen Javier Gutierrez-Achury Isis Ricaño-Ponce David van Heel Einar Björnsson Richard N Sandford Peter R Durie Espen Melum Morten H Vatn Mark S Silverberg Richard H Duerr Leonid Padyukov Stephan Brand Miquel Sans Vito Annese Jean-Paul Achkar Kirsten Muri Boberg Hanns-Ulrich Marschall Olivier Chazouillères Christopher L Bowlus Cisca Wijmenga Erik Schrumpf Severine Vermeire Mario Albrecht John D Rioux Graeme Alexander Annika Bergquist Judy Cho Stefan Schreiber Michael P Manns Martti Färkkilä Anders M Dale Roger W Chapman Konstantinos N Lazaridis Andre Franke Carl A Anderson Tom H Karlsen

Nat Genet 2013 Jun 21;45(6):670-5. Epub 2013 Apr 21.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.2616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667736PMC
June 2013

Improvement of serum alkaline phosphatase to <1.5 upper limit of normal predicts better outcome and reduced risk of cholangiocarcinoma in primary sclerosing cholangitis.

Authors:
Said Al Mamari Jelena Djordjevic John S Halliday Roger W Chapman

J Hepatol 2013 Feb 22;58(2):329-34. Epub 2012 Oct 22.

Transitional Gastroenterology Unit, Oxford University Hospitals, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.jhep.2012.10.013DOI Listing
February 2013

Cholangiocarcinoma complicating secondary sclerosing cholangitis from cryptosporidiosis in an adult patient with CD40 ligand deficiency: case report and review of the literature.

Authors:
Monira Rahman Helen Chapel Roger W Chapman Jane D Collier

Int Arch Allergy Immunol 2012 1;159(2):204-8. Epub 2012 Jun 1.

Department of Hepatology, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1159/000337457DOI Listing
December 2012

Fine mapping and replication of genetic risk loci in primary sclerosing cholangitis.

Authors:
Brijesh Srivastava George F Mells Heather J Cordell Agnes Muriithi Matthew Brown Eva Ellinghaus Andre Franke Tom H Karlsen Richard N Sandford Graeme J Alexander Roger W Chapman Simon M Rushbrook Espen Melum

Scand J Gastroenterol 2012 Jul 4;47(7):820-6. Epub 2012 May 4.

Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.3109/00365521.2012.682090DOI Listing
July 2012

A rare cause of an ileocaecal mass and lymphadenopathy.

Authors:
Emma L Culver Eleanor Barnes David Delaney Antony J Ellis Bruce George Roger W Chapman

Gut 2012 Jun 3;61(6):819-20, 917. Epub 2011 Sep 3.

Gastroenterology Specialist Registrar and Wellcome Trust Research Training Fellow, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1136/gutjnl-2011-300838DOI Listing
June 2012

Risk for colorectal neoplasia in patients with colonic Crohn's disease and concomitant primary sclerosing cholangitis.

Authors:
Barbara Braden Johnny Halliday Sanjeewa Aryasingha Yalda Sharifi Davide Checchin Bryan F Warren Taya Kitiyakara Simon P L Travis Roger W Chapman

Clin Gastroenterol Hepatol 2012 Mar 28;10(3):303-8. Epub 2011 Oct 28.

Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.cgh.2011.10.020DOI Listing
March 2012

Primary sclerosing cholangitis: is any treatment worthwhile?

Authors:
Ashley Barnabas Roger W Chapman

Curr Gastroenterol Rep 2012 Feb;14(1):17-24

Translational Gastroenterology unit, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK.

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http://dx.doi.org/10.1007/s11894-011-0230-8DOI Listing
February 2012

No more pilots, a phase III trial of fibrates in primary biliary cirrhosis is long overdue!

Authors:
John S Halliday Roger W Chapman

J Gastroenterol Hepatol 2011 Sep;26(9):1345-6

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http://dx.doi.org/10.1111/j.1440-1746.2011.06837.xDOI Listing
September 2011

The clinical impact of primary sclerosing cholangitis in patients with an ileal pouch-anal anastomosis for ulcerative colitis.

Authors:
Monira Rahman Paul Desmond Neil Mortensen Roger W Chapman

Int J Colorectal Dis 2011 May 29;26(5):553-9. Epub 2011 Jan 29.

Department of Gastroenterology, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1007/s00384-011-1140-9DOI Listing
May 2011

Overlap syndromes: the International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue.

Authors:
Kirsten Muri Boberg Roger W Chapman Gideon M Hirschfield Ansgar W Lohse Michael P Manns Erik Schrumpf

J Hepatol 2011 Feb 18;54(2):374-85. Epub 2010 Sep 18.

Clinic for Specialized Medicine and Surgery, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1016/j.jhep.2010.09.002DOI Listing
February 2011

The diagnostic significance of serum IgG4 levels in patients with autoimmune pancreatitis: a UK study.

Authors:
Ross Sadler Roger W Chapman Dawn Simpson Zahir F Soonawalla Elizabeth L Waldegrave John M Burden Siraj A Misbah Berne L Ferry

Eur J Gastroenterol Hepatol 2011 Feb;23(2):139-45

Department of Immunology, Churchill Hospital, John Radcliffe Hospital, Oxford Radcliffe Trust, Oxford, UK.

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http://dx.doi.org/10.1097/meg.0b013e3283423486DOI Listing
February 2011

Biliary tract: microbiological analysis of bile during cholangiography.

Authors:
Antony J Ellis Roger W Chapman

Nat Rev Gastroenterol Hepatol 2010 Dec;7(12):655-6

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http://dx.doi.org/10.1038/nrgastro.2010.167DOI Listing
December 2010

Management of patients with biliary sphincter of Oddi disorder without sphincter of Oddi manometry.

Authors:
Evangelos Kalaitzakis Tim Ambrose Jane Phillips-Hughes Jane Collier Roger W Chapman

BMC Gastroenterol 2010 Oct 22;10:124. Epub 2010 Oct 22.

Department of Gastroenterology, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1186/1471-230X-10-124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975654PMC
October 2010

Fatigue measurements in patients with primary biliary cirrhosis and the risk of mortality during follow-up.

Authors:
Einar Björnsson Evangelos Kalaitzakis Matthias Neuhauser Felicity Enders Hardy Maetzel Roger W Chapman Jayant Talwalkar Keith Lindor Roberta Jorgensen

Liver Int 2010 Feb 17;30(2):251-8. Epub 2009 Nov 17.

Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/j.1478-3231.2009.02160.xDOI Listing
February 2010

Primary sclerosing cholangitis: what is the role of ursodeoxycholic acid in therapy for PSC?

Authors:
Roger W Chapman

Nat Rev Gastroenterol Hepatol 2010 Feb;7(2):74-5

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http://dx.doi.org/10.1038/nrgastro.2009.235DOI Listing
February 2010

High-dose ursodeoxycholic acid in the treatment of primary sclerosing cholangitis: throwing the urso out with the bathwater?

Authors:
Roger W Chapman

Hepatology 2009 Sep;50(3):671-3

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http://dx.doi.org/10.1002/hep.23174DOI Listing
September 2009

Autoimmune pancreatitis/IgG4-associated cholangitis and primary sclerosing cholangitis--overlapping or separate diseases?

Authors:
George J M Webster Stephen P Pereira Roger W Chapman

J Hepatol 2009 Aug 12;51(2):398-402. Epub 2009 May 12.

Department of Gastroenterology, University College Hospital, 235 Euston Road, London NW1, UK.

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http://dx.doi.org/10.1016/j.jhep.2009.04.010DOI Listing
August 2009

Addition of senna improves quality of colonoscopy preparation with magnesium citrate.

Authors:
Stergios Vradelis Evangelos Kalaitzakis Yalda Sharifi Otto Buchel Satish Keshav Roger W Chapman Barbara Braden

World J Gastroenterol 2009 Apr;15(14):1759-63

Gastroenterology Department, John Radcliffe Hospital, Headley Way, Oxford, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668782PMC
http://dx.doi.org/10.3748/wjg.15.1759DOI Listing
April 2009

High dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis is safe and effective.

Authors:
Susan N Cullen Christian Rust Kenneth Fleming Cathryn Edwards Ulrich Beuers Roger W Chapman

J Hepatol 2008 May 14;48(5):792-800. Epub 2008 Feb 14.

Gastroenterology Department, Wycombe General Hospital, High Wycombe, UK.

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http://dx.doi.org/10.1016/j.jhep.2007.12.023DOI Listing
May 2008

An update on primary sclerosing cholangitis.

Authors:
James Rl Maggs Roger W Chapman

Curr Opin Gastroenterol 2008 May;24(3):377-83

Department of Gastroenterology, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1097/MOG.0b013e3282f9e239DOI Listing
May 2008

The natural history of small-duct primary sclerosing cholangitis.

Authors:
Einar Björnsson Rolf Olsson Annika Bergquist Stefan Lindgren Barbara Braden Roger W Chapman Kirsten M Boberg Paul Angulo

Gastroenterology 2008 Apr 17;134(4):975-80. Epub 2008 Jan 17.

Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1053/j.gastro.2008.01.042DOI Listing
April 2008

Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection.

Authors:
Scott M Ward Bridget C Fox Philip J Brown Joy Worthington Stephen B Fox Roger W Chapman Kenneth A Fleming Alison H Banham Paul Klenerman

J Hepatol 2007 Sep 12;47(3):316-24. Epub 2007 Apr 12.

Peter Medawar Building for Pathogen Research, Nuffield Department of Clinical Medicine, University of Oxford, South Parks Road, Oxford, UK.

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http://dx.doi.org/10.1016/j.jhep.2007.03.023DOI Listing
September 2007

Sclerosing cholangitis.

Authors:
James Rl Maggs Roger W Chapman

Curr Opin Gastroenterol 2007 May;23(3):310-6

Department of Gastroenterology, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1097/MOG.0b013e32805867e6DOI Listing
May 2007

Sclerosing cholangitis.

Authors:
George R MacFaul Roger W Chapman

Curr Opin Gastroenterol 2006 May;22(3):288-93

Department of Gastroenterology, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1097/01.mog.0000218966.78558.67DOI Listing
May 2006

The medical management of primary sclerosing cholangitis.

Authors:
Susan N Cullen Roger W Chapman

Semin Liver Dis 2006 Feb;26(1):52-61

Wycombe General Hospital, High Wycombe, United Kingdom.

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http://dx.doi.org/10.1055/s-2006-933563DOI Listing
February 2006

Sclerosing cholangitis.

Authors:
George R MacFaul Roger W Chapman

Curr Opin Gastroenterol 2005 May;21(3):348-53

Department of Gastroenterology, John Radcliffe Hospital, Oxford, UK.

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May 2005

Fatigue is not a specific symptom in patients with primary biliary cirrhosis.

Authors:
Einar Björnsson Magnus Simren Rolf Olsson Roger W Chapman

Eur J Gastroenterol Hepatol 2005 Mar;17(3):351-7

Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg Sweden.

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http://pdfs.journals.lww.com/eurojgh/2005/03000/Fatigue_is_n
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http://dx.doi.org/10.1097/00042737-200503000-00015DOI Listing
March 2005

Sclerosing cholangitis.

Authors:
George R MacFaul Roger W Chapman

Curr Opin Gastroenterol 2004 May;20(3):275-80

Department of Gastroenterology, John Radcliffe Hospital, Oxford, United Kingdom.

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May 2004

Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1.

Authors:
Xuesong Yang Susan N Cullen Jin H Li Roger W Chapman Derek P Jewell

J Hepatol 2004 Mar;40(3):375-9

Gastroenterology Unit, Gibson Laboratories, Nuffield Department of Medicine, University of Oxford, 2nd Floor, Radcliffe Infirmary, Oxford OX2 6HE, UK.

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http://dx.doi.org/10.1016/j.jhep.2003.11.009DOI Listing
March 2004

Digenic inheritance of mutations in HAMP and HFE results in different types of haemochromatosis.

Authors:
Alison T Merryweather-Clarke Estelle Cadet Adrian Bomford Dominique Capron Vip Viprakasit Anne Miller Paddy J McHugh Roger W Chapman Jennifer J Pointon Victoria L C Wimhurst Karen J Livesey Voravarn Tanphaichitr Jacques Rochette Kathryn J H Robson

Hum Mol Genet 2003 Sep 15;12(17):2241-7. Epub 2003 Jul 15.

MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Headley Way, Oxford OX3 9DS, UK.

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http://dx.doi.org/10.1093/hmg/ddg225DOI Listing
September 2003

Sclerosing cholangitis.

Authors:
Einar Björnsson Roger W Chapman

Curr Opin Gastroenterol 2003 May;19(3):270-5

Department of Internal Medicine, Section of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden.

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May 2003

The management of primary sclerosing cholangitis.

Authors:
Roger W Chapman

Curr Gastroenterol Rep 2003 Feb;5(1):9-17

Department of Hepatology and Gastroenterology, Oxford Radcliffe Hospital, Oxford OX3 9DU, UK.

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February 2003

Small duct primary sclerosing cholangitis.

Authors:
Roger W Chapman

J Hepatol 2002 May;36(5):692-4

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http://dx.doi.org/10.1016/s0168-8278(02)00085-5DOI Listing
May 2002