Roger Stupp

Roger Stupp

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Roger Stupp

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Overcoming the Blood-Brain Barrier with an Implantable Ultrasound Device.

Clin Cancer Res 2019 Jul 10;25(13):3750-3752. Epub 2019 May 10.

Malnati Brain Tumor Institute, Lurie Comprehensive Cancer Center and Departments of Neurological Surgery and Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-0932DOI Listing
July 2019

Are Integrins Still Practicable Targets for Anti-Cancer Therapy?

Cancers (Basel) 2019 Jul 12;11(7). Epub 2019 Jul 12.

Pathology Unit, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Chemin du Musée 18, Per 17, CH-1700 Fribourg, Switzerland.

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http://dx.doi.org/10.3390/cancers11070978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678560PMC
July 2019

Use of metformin and outcome of patients with newly diagnosed glioblastoma: Pooled analysis.

Int J Cancer 2019 Apr 13. Epub 2019 Apr 13.

Department of Neurology and Wilhelm Sander-NeuroOncology Unit, Regensburg University Hospital, Regensburg, Germany.

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http://dx.doi.org/10.1002/ijc.32337DOI Listing
April 2019

Improving survival in molecularly selected glioblastoma.

Lancet 2019 02 14;393(10172):615-617. Epub 2019 Feb 14.

Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1016/S0140-6736(18)33211-2DOI Listing
February 2019

Drug development for glioma: are we repeating the same mistakes?

Authors:
Roger Stupp

Lancet Oncol 2019 Jan 3;20(1):10-12. Epub 2018 Dec 3.

Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183082
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http://dx.doi.org/10.1016/S1470-2045(18)30827-1DOI Listing
January 2019

Associations of anticoagulant use with outcome in newly diagnosed glioblastoma.

Eur J Cancer 2018 09 20;101:95-104. Epub 2018 Jul 20.

Department of Neurology & Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.ejca.2018.06.029DOI Listing
September 2018

Treatment strategies and outcome of surgery for synchronous colorectal liver metastases.

Swiss Med Wkly 2017 15;147:w14486. Epub 2017 Aug 15.

Department of Oncology, Swiss HPB-Centre, University Hospital Zurich, Switzerland.

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http://dx.doi.org/10.4414/smw.2017.14486DOI Listing
June 2018

Diagnostic value of F-fluordesoxyglucose positron emission tomography for patients with brain metastasis from unknown primary site.

Eur J Cancer 2018 06 17;96:64-72. Epub 2018 Apr 17.

Department of Neurology and Brain Tumor Center, University Hospital and University of Zurich, Frauenklinikstrasse 26, CH-8091, Zurich, Switzerland; Neuro-oncology, Department of Neurosurgery, University Hospital Lille, Salengro Hospital, Rue Emile Laine, FR-59037, Lille, France; Neurology, Department of Medical Oncology, Oscar Lambret Center, FR-59020, Lille, France; Inserm U-1192, Villeneuve d'Ascq, France.

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http://dx.doi.org/10.1016/j.ejca.2018.03.010DOI Listing
June 2018

B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma.

Diagn Pathol 2018 Jun 5;13(1):37. Epub 2018 Jun 5.

Departments of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Tarry 2-705, 300 East Superior Street, Chicago, IL, 60611, USA.

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http://dx.doi.org/10.1186/s13000-018-0717-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989478PMC
June 2018

Do statins, ACE inhibitors or sartans improve outcome in primary glioblastoma?

J Neurooncol 2018 May 8;138(1):163-171. Epub 2018 Feb 8.

Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.

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http://link.springer.com/10.1007/s11060-018-2786-8
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http://dx.doi.org/10.1007/s11060-018-2786-8DOI Listing
May 2018

Quality of Life in Patients With Glioblastoma Treated With Tumor-Treating Fields-Reply.

Authors:
Roger Stupp Zvi Ram

JAMA 2018 05;319(17):1823

Department of Neurosurgery, Tel Aviv Medical Center, Tel Aviv, Israel.

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http://dx.doi.org/10.1001/jama.2018.1862DOI Listing
May 2018

CAR T-Cell Therapies in Glioblastoma: A First Look.

Clin Cancer Res 2018 02 20;24(3):535-540. Epub 2017 Nov 20.

Center for Cellular Immunotherapies and Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-2871DOI Listing
February 2018

Primary Central Nervous System Lymphoma-PART 2: Modern Therapeutic Management and Future Directions.

Oncology (Williston Park) 2018 02 15;32(2):e11-e19. Epub 2018 Feb 15.

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February 2018

Ipilimumab and early signs of pulmonary toxicity in patients with metastastic melanoma: a prospective observational study.

Cancer Immunol Immunother 2018 01 5;67(1):127-134. Epub 2017 Oct 5.

Department of Pulmonology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00262-017-2071-2DOI Listing
January 2018

Hospital volume and group expertise in newly diagnosed glioblastoma management.

J Neurooncol 2018 Jan 7;136(1):213-214. Epub 2017 Oct 7.

Northwestern University, 710 N. Lake Shore Drive, Abbott Hall 710, Chicago, IL, 60611, USA.

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http://dx.doi.org/10.1007/s11060-017-2632-4DOI Listing
January 2018

MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma.

Cancer Cell 2017 Dec;32(6):840-855.e8

Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA; The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734934PMC
December 2017

Lomustine and Bevacizumab in Progressive Glioblastoma.

N Engl J Med 2017 11;377(20):1954-1963

From the University Medical Center and German Cancer Research Center, Heidelberg, Germany (W.W., M.B., F.S., I.H., A.D., M.P.); the European Organization for Research and Treatment of Cancer, Brussels (T.G., V.G.), and Leuven Cancer Institute-KU Leuven, Leuven (P.M.C.) - both in Belgium; Haaglanden Medical Center, The Hague (M.T.), Erasmus MC Cancer Institute, Rotterdam (W.T., J.C.B., M.J.B.), and VU University Medical Center, Amsterdam (M.K.) - all in the Netherlands; the Medical Oncology Department, Azienda Unità Sanitaria Locale di Bologna-IRCCS Istituto delle Scienze Neurologiche, Bologna, Italy (A.A.B.); Institut Gustave Roussy, Villejuif (J.D.), Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Service de Neurologie 2-Mazarin, INSERM Unité 1127, Centre National de la Recherche Scientifique Unité Mixte de Recherche (UMR) 7225, Sorbonne Universités, University Pierre and Marie Curie 06 UMR S1127, and Institut du Cerveau et de la Moelle Épinière, Paris (A.I.), Institut de Cancerologie de l'Ouest-Centre Rene Gauducheau, Saint-Herblain (M.C.), Institut Régional du Cancer Montpellier, Montpellier (M.F.), and Centre Hospitalier Régional Universitaire de Lille, Lille (E.L.R., F.D.) - all in France; and the Departments of Oncology and Neurology, University Hospital and University of Zurich, Zurich, Switzerland (R.S., M.W.).

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http://dx.doi.org/10.1056/NEJMoa1707358DOI Listing
November 2017

Is more better? The impact of extended adjuvant temozolomide in newly diagnosed glioblastoma: a secondary analysis of EORTC and NRG Oncology/RTOG.

Neuro Oncol 2017 Aug;19(8):1119-1126

Tel-Aviv Sourasky Medical Center, Tel-Aviv University; European Organization for Research and Treatment of Cancer, Brussels (EORTC); National Institutes of Health (M.R.M.); University of Alabama at Birmingham; Princess Margaret Cancer Centre, University of Toronto; Lausanne University Hospital; NRG Oncology Statistics and Data Management Center; Odette Cancer Centre and Sunnybrook Health Sciences Centre, University of Toronto; Samsung Medical Center, Sungkyunkwan University School of Medicine; Edinburgh Cancer Centre; Mayo Clinic; Robert-Janker Clinic at the University of Bonn Medical Centre, and MAASTRO clinic, GROW School for Oncology, Maastricht University Medical Centre; Miami Cancer Institute; Erasmus University Hospital; Dana-Farber Cancer Institute and Harvard Medical School; University of Zurich.

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http://dx.doi.org/10.1093/neuonc/nox025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570239PMC
August 2017

Evidence-based management of adult patients with diffuse glioma - Authors' reply.

Lancet Oncol 2017 08 26;18(8):e430-e431. Epub 2017 Jul 26.

Neurology Clinic and National Centre for Tumour Diseases, University Hospital Heidelberg, Heidelberg, Germany; German Consortium of Translational Cancer Research, Clinical Cooperation Unit Neurooncology, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1016/S1470-2045(17)30515-6DOI Listing
August 2017

European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas.

Lancet Oncol 2017 06 5;18(6):e315-e329. Epub 2017 May 5.

Neurology Clinic and National Centre for Tumour Diseases, University Hospital Heidelberg, Heidelberg, Germany; German Consortium of Translational Cancer Research (DKTK), Clinical Cooperation Unit Neurooncology, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1016/S1470-2045(17)30194-8DOI Listing
June 2017

Biological activity of tumor-treating fields in preclinical glioma models.

Cell Death Dis 2017 04 20;8(4):e2753. Epub 2017 Apr 20.

Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/cddis.2017.171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477589PMC
April 2017

Toxicity of concurrent stereotactic radiotherapy and targeted therapy or immunotherapy: A systematic review.

Cancer Treat Rev 2017 Feb 19;53:25-37. Epub 2016 Dec 19.

Department of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.ctrv.2016.11.013DOI Listing
February 2017

Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.

Lancet Oncol 2016 Nov 27;17(11):1533-1542. Epub 2016 Sep 27.

Department of Medical Oncology and Cancer Centre, University Hospital Zurich, Zurich, Switzerland; Department of Radiation-Oncology (MAASTRO), Maastricht University Medical Centre (MUMC) and GROW (School for Oncology), Maastricht, Netherlands; Department of Radiation-Oncology, MediClin Robert-Janker-Clinic, Clinical Cooperation Unit Neuro-oncology, University Bonn Medical Centre, Bonn, Germany.

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http://dx.doi.org/10.1016/S1470-2045(16)30305-9DOI Listing
November 2016

Tumor treating fields: a novel treatment modality and its use in brain tumors.

Neuro Oncol 2016 10;18(10):1338-49

CHUV University Hospital and Lausanne University, Departments of Clinical Neurosciences and Oncology, Lausanne, Switzerland (A.F.H., P.P.); University Hospital Zurich and University of Zurich, Department of Oncology, Zurich, Switzerland (R.S.)

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http://dx.doi.org/10.1093/neuonc/now182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035531PMC
October 2016

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016.

Authors:
Christian Dittrich Michael Kosty Svetlana Jezdic Doug Pyle Rossana Berardi Jonas Bergh Nagi El-Saghir Jean-Pierre Lotz Pia Österlund Nicholas Pavlidis Gunta Purkalne Ahmad Awada Susana Banerjee Smita Bhatia Jan Bogaerts Jan Buckner Fatima Cardoso Paolo Casali Edward Chu Julia Lee Close Bertrand Coiffier Roisin Connolly Sarah Coupland Luigi De Petris Maria De Santis Elisabeth G E de Vries Don S Dizon Jennifer Duff Linda R Duska Alexandru Eniu Marc Ernstoff Enriqueta Felip Martin F Fey Jill Gilbert Nicolas Girard Andor W J M Glaudemans Priya K Gopalan Axel Grothey Stephen M Hahn Diana Hanna Christian Herold Jørn Herrstedt Krisztian Homicsko Dennie V Jones Lorenz Jost Ulrich Keilholz Saad Khan Alexander Kiss Claus-Henning Köhne Rainer Kunstfeld Heinz-Josef Lenz Stuart Lichtman Lisa Licitra Thomas Lion Saskia Litière Lifang Liu Patrick J Loehrer Merry Jennifer Markham Ben Markman Marius Mayerhoefer Johannes G Meran Olivier Michielin Elizabeth Charlotte Moser Giannis Mountzios Timothy Moynihan Torsten Nielsen Yuichiro Ohe Kjell Öberg Antonio Palumbo Fedro Alessandro Peccatori Michael Pfeilstöcker Chandrajit Raut Scot C Remick Mark Robson Piotr Rutkowski Roberto Salgado Lidia Schapira Eva Schernhammer Martin Schlumberger Hans-Joachim Schmoll Lowell Schnipper Cristiana Sessa Charles L Shapiro Julie Steele Cora N Sternberg Friedrich Stiefel Florian Strasser Roger Stupp Richard Sullivan Josep Tabernero Luzia Travado Marcel Verheij Emile Voest Everett Vokes Jamie Von Roenn Jeffrey S Weber Hans Wildiers Yosef Yarden

ESMO Open 2016 29;1(5):e000097. Epub 2016 Sep 29.

Department of General Medical Oncology , University Hospitals Leuven , Leuven , Belgium.

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http://dx.doi.org/10.1136/esmoopen-2016-000097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070299PMC
September 2016

Treatment for Patients With Newly Diagnosed Glioblastoma--Reply.

JAMA 2016 Jun;315(21):2348-9

Department of Translational Neuro-Oncology and Neurotherapeutics, John Wayne Cancer Institute, Santa Monica, California.

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http://dx.doi.org/10.1001/jama.2016.1847DOI Listing
June 2016

Corticosteroids compromise survival in glioblastoma.

Brain 2016 05 28;139(Pt 5):1458-71. Epub 2016 Mar 28.

2 Department of Neurosciences at the Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, 44195, USA 3 Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA

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http://brain.oxfordjournals.org/content/brain/early/2016/03/
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http://pdfs.journals.lww.com/neurosurgery/2016/10000/Do_Cort
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http://dx.doi.org/10.1093/brain/aww046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006251PMC
May 2016

Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma.

J Clin Oncol 2016 Mar 19;34(7):731-9. Epub 2016 Jan 19.

Caroline Happold, Patrick Roth, Roger Stupp, and Michael Weller, University Hospital Zurich; Monika Hegi, University Hospital Lausanne, Switzerland; Thierry Gorlia, EORTC Data Centre, Brussels, Belgium; Olivier Chinot, Aix-Marseille University, Marseille, France; Mark R. Gilbert, The University of Texas MD Anderson Cancer Center, Houston, TX; L. Burt Nabors, University of Alabama at Birmingham, Birmingham, AL; Wolfgang Wick, University of Heidelberg & German Cancer Research Center, Heidelberg, Germany; Stephanie L. Pugh, NRG Oncology Statistics and Data Management Center, Philadelphia, PA; Timothy Cloughesy, UCLA Neuro-Oncology Program, Los Angeles, CA; David A. Reardon, Dana-Farber Cancer Institute, Boston, MA; James R. Perry, University of Toronto, Toronto, Ontario, Canada; and Minesh P. Mehta, University of Maryland, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2015.63.6563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070573PMC
March 2016

[Gliomas – What I Have to Know in ten Questions].

Praxis (Bern 1994) 2016 Mar;105(6):330-7

1 Hirntumorzentrum, Universitätsspital Zürich.

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http://dx.doi.org/10.1024/1661-8157/a002303DOI Listing
March 2016

Withholding temozolomide in glioblastoma patients with unmethylated MGMT promoter--still a dilemma?

Neuro Oncol 2015 Nov 15;17(11):1425-7. Epub 2015 Sep 15.

Neuroscience Research Center, and Service of Neurosurgery, Lausanne University Hospital, Lausanne (CHUV) (M.E.H); Department of Oncology, University Hospital Zurich, Zurich, Switzerland (R.S).

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http://dx.doi.org/10.1093/neuonc/nov198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648310PMC
November 2015

Glioma.

Nat Rev Dis Primers 2015 07 16;1:15017. Epub 2015 Jul 16.

Department of Neuropathology, Heinrich Heine University Düsseldorf, and German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ) Heidelberg, partner site Essen/Düsseldorf, Germany.

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http://dx.doi.org/10.1038/nrdp.2015.17DOI Listing
July 2015

Does cilengitide deserve another chance?-Authors' reply.

Lancet Oncol 2014 Dec 24;15(13):e585-e586. Epub 2014 Nov 24.

University Hospital Zurich, 8006 Zurich, Switzerland; European Organisation for Research and Treatment of Cancer, Brussels, Belgium.

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http://dx.doi.org/10.1016/S1470-2045(14)71121-0DOI Listing
December 2014

Addition of lomustine for bevacizumab-refractory recurrent glioblastoma.

Acta Oncol 2014 Oct 26;53(10):1436-40. Epub 2014 May 26.

Department of Neurology, University Hospital Zurich , Zurich , Switzerland.

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http://dx.doi.org/10.3109/0284186X.2014.920960DOI Listing
October 2014

The level of patient-reported outcome reporting in randomised controlled trials of brain tumour patients: a systematic review.

Eur J Cancer 2014 Sep 14;50(14):2432-48. Epub 2014 Jul 14.

Italian Group for Adult Hematologic Diseases (GIMEMA), Data Center and Health Outcomes Research Unit, Rome, Italy.

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http://dx.doi.org/10.1016/j.ejca.2014.06.016DOI Listing
September 2014

European perspective for effective cancer drug development.

Nat Rev Clin Oncol 2014 08 17;11(8):492-8. Epub 2014 Jun 17.

UniversitaetsSpital Zurich, Division of Oncology, Raemistrasse 100, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1038/nrclinonc.2014.98DOI Listing
August 2014

EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma.

Lancet Oncol 2014 Aug;15(9):e395-403

Department of Neurooncology, Neurology Clinic & National Center for Tumor Diseases, University Hospital Heidelberg, Germany; German Consortium of Translational Cancer Research, Clinical Cooperation Unit Neurooncology, German Cancer Research Center, Heidelberg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S14702045147001
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http://dx.doi.org/10.1016/S1470-2045(14)70011-7DOI Listing
August 2014

Clinical management and outcome of histologically verified adult brainstem gliomas in Switzerland: a retrospective analysis of 21 patients.

J Neurooncol 2014 Jun 16;118(2):321-328. Epub 2014 Apr 16.

Department of Neurology, and Brain Tumor Center, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s11060-014-1434-1DOI Listing
June 2014

The changing world of drug development: an academic research organization's perspective on the "Seven Wonders" of the future world of anticancer drug development.

Chin Clin Oncol 2014 Jun;3(2):19

European Organisation for Research and Treatment of Cancer (EORTC), Brussels, Belgium; Department of Oncology and Cancer Center, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.3978/j.issn.2304-3865.2014.05.06DOI Listing
June 2014

Levetiracetam and pregabalin for antiepileptic monotherapy in patients with primary brain tumors. A phase II randomized study.

Neuro Oncol 2014 Apr 4;16(4):584-8. Epub 2013 Dec 4.

Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne, Lausanne, Switzerland (A.O.R., J.N., R.S.); Multidisciplinary Oncology Center, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne, Lausanne, Switzerland (S.J.); Department of Neurology, Universitätspital Zürich, Zurich, Switzerland (P.R., M.W.).

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http://dx.doi.org/10.1093/neuonc/not170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956345PMC
April 2014

Treatment of primary CNS lymphoma.

Curr Treat Options Neurol 2014 Jan;16(1):277

Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091, Zurich, Switzerland,

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http://dx.doi.org/10.1007/s11940-013-0277-yDOI Listing
January 2014

Standards of care and novel approaches in the management of glioblastoma multiforme.

Chin J Cancer 2014 Jan;33(1):32-9

Department of Clinical Neuroscience, Lausanne University Hospital, Lausanne 1011, Switzerland.

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http://dx.doi.org/10.5732/cjc.013.10207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905088PMC
January 2014

Malignant astrocytoma in elderly patients: where do we stand?

Curr Opin Neurol 2013 Dec;26(6):693-700

aDepartment of Neurology bDepartment of Medical Oncology, University Hospital Zurich, Zurich, Switzerland cDepartment of Neurooncology, National Center for Tumor Disease and Neurology Clinic, University Hospital Heidelberg, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1097/WCO.0000000000000037DOI Listing
December 2013

Molecular imaging in the development of a novel treatment paradigm for glioblastoma (GBM): an integrated multidisciplinary commentary.

Drug Discov Today 2013 Nov 20;18(21-22):1052-66. Epub 2013 Jun 20.

Department of Physiology and Medical Physics & Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.drudis.2013.06.004DOI Listing
November 2013

New validated prognostic models and prognostic calculators in patients with low-grade gliomas diagnosed by central pathology review: a pooled analysis of EORTC/RTOG/NCCTG phase III clinical trials.

Neuro Oncol 2013 Nov 18;15(11):1568-79. Epub 2013 Sep 18.

Corresponding Author: M. Thierry Gorlia, The European Organisation for Research and Treatment of Cancer (EORTC) Headquarters, 83 Avenue E. Mounier, 1200 Brussels, Belgium.

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http://dx.doi.org/10.1093/neuonc/not117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813419PMC
November 2013

Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.

J Clin Oncol 2013 Nov 7;31(32):4085-91. Epub 2013 Oct 7.

Mark R. Gilbert, Kenneth D. Aldape, Terri S. Armstrong, Jeffrey S. Wefel, Anita Mahajan, and Paul D. Brown, University of Texas MD Anderson Cancer Center; Terri S. Armstrong, University of Texas Health Science Center-School of Nursing, Houston, TX; Meihua Wang and Minhee Won, Radiation Therapy Oncology Group Statistical Center, Philadelphia, PA; Roger Stupp and Monika E. Hegi, Lausanne University Hospitals, Lausanne, Switzerland; Kurt A. Jaeckle, Mayo Clinic Florida, Jacksonville, FL; Deborah T. Blumenthal, Tel Aviv Medical Center, Tel Aviv; Tzahala Tzuk-Shina, Rambam Medical Center, Haifa, Israel; Christopher J. Schultz, Medical College of Wisconsin, Milwaukee, WI; Sara Erridge, University of Edinburgh, Edinburgh, Scotland; Brigitta G. Baumert, Maastricht University Medical Center, Maastricht, the Netherlands; Kristen I. Hopkins, University Hospitals Bristol, Bristol, United Kingdom; Arnab Chakravarti, Arthur G. James Cancer Hospital/Ohio State University Comprehensive Cancer Center, Columbus, OH; Walter J. Curran Jr, Emory University Winship Cancer Center, Atlanta, GA; and Minesh P. Mehta, University of Maryland, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2013.49.6968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816958PMC
November 2013

Neuro-oncology: in search of molecular markers of glioma in elderly patients.

Nat Rev Neurol 2013 Aug 2;9(8):424-5. Epub 2013 Jul 2.

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http://dx.doi.org/10.1038/nrneurol.2013.127DOI Listing
August 2013

Molecular neuro-oncology in clinical practice: a new horizon.

Lancet Oncol 2013 Aug;14(9):e370-9

Department of Neurology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/S1470-2045(13)70168-2DOI Listing
August 2013

Cancer clinical trials--do we need a new algorithm in the age of stratified medicine?

Oncologist 2013 Jun;18(6):651-2

Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1634/theoncologist.2013-0190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063387PMC
June 2013

PET Imaging in Glioma: The Neuro-Oncologist's Expectations.

PET Clin 2013 Apr 28;8(2):117-28. Epub 2012 Nov 28.

Department of Clinical Neurosciences, Lausanne University Hospital, Rue du Bugnon 46, Lausanne 1011, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cpet.2012.09.006DOI Listing
April 2013

Brain cancer in 2012: Molecular characterization leads the way.

Nat Rev Clin Oncol 2013 Feb 8;10(2):69-70. Epub 2013 Jan 8.

Division of Neurosurgery, Department of Clinical Neurosciences, University of Lausanne Hospital, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/nrclinonc.2012.240DOI Listing
February 2013

Brain metastasis: opportunity for drug development?

Curr Opin Neurol 2012 Dec;25(6):786-94

Department of Medicine I and Comprehensive Cancer Center CNS Unit, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1097/WCO.0b013e328359320dDOI Listing
December 2012

Personalized care in neuro-oncology coming of age: why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice.

Neuro Oncol 2012 Sep;14 Suppl 4:iv100-8

Department of Neurology, University Hospital Zurich and Center for Neurosciences, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1093/neuonc/nos206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480248PMC
September 2012