Roger N Rosenberg

Roger N Rosenberg

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Roger N Rosenberg

Roger N Rosenberg

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Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gena Roschupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019

Active full-length DNA Aβ immunization in 3xTg-AD mice reduces not only amyloid deposition but also tau pathology.

Alzheimers Res Ther 2018 11 20;10(1):115. Epub 2018 Nov 20.

Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center Dallas, 5323 Harry Hines Boulevard, Dallas, TX, 75390-8813, USA.

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https://alzres.biomedcentral.com/articles/10.1186/s13195-018
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http://dx.doi.org/10.1186/s13195-018-0441-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245829PMC
November 2018

Intradermal active full-length DNA Aβ42 immunization via electroporation leads to high anti-Aβ antibody levels in wild-type mice.

J Neuroimmunol 2018 Sep 11;322:15-25. Epub 2018 Jun 11.

Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center Dallas, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2018.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192700PMC
September 2018

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.3916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669039PMC
September 2017

Laquinimod has no effects on brain volume or cellular CNS composition in the F1 3xTg-AD/C3H mouse model of Alzheimer's disease.

J Neuroimmunol 2017 08 26;309:100-110. Epub 2017 May 26.

Department of Neurology and Neurotherapeutics, the University of Texas Southwestern Medical Center at Dallas, USA; Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Germany; Neurology Section, VA North Texas Health Care System, Medical Service Dallas, VA Medical Center, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2017.05.017DOI Listing
August 2017

Evaluation of a DNA Aβ42 vaccine in adult rhesus monkeys (Macaca mulatta): antibody kinetics and immune profile after intradermal immunization with full-length DNA Aβ42 trimer.

Alzheimers Res Ther 2017 Apr 26;9(1):30. Epub 2017 Apr 26.

Department of Neurology and Neurotherapeutics, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390-8813, USA.

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http://dx.doi.org/10.1186/s13195-017-0257-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405538PMC
April 2017

JAMA Neurology at the Forefront, 1997-2016.

JAMA Neurol 2016 12;73(12):1392-1394

Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas2Editor, JAMA Neurology.

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http://dx.doi.org/10.1001/jamaneurol.2016.3943DOI Listing
December 2016

Genomics of Alzheimer Disease: A Review.

JAMA Neurol 2016 Jul;73(7):867-74

Geriatric Research, Education and Clinical Center, Bedford Veterans Hospital, Bedford, Massachusetts5Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaneurol.2016.0301DOI Listing
July 2016

Circuits and Circuit Disorders: Approaches to Neuromodulation.

JAMA Neurol 2015 Nov;72(11):1232

Department of Neurology, University of Texas Southwestern Medical Center, Dallas2Editor, JAMA Neurology.

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http://dx.doi.org/10.1001/jamaneurol.2015.2624DOI Listing
November 2015

The Human Alzheimer Disease Project: A New Call to Arms.

JAMA Neurol 2015 Jun;72(6):626-8

Alzheimer's Disease Research Center, Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota.

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http://www.bu.edu/alzresearch/files/2015/04/Rosenberg-and-Pe
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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
Publisher Site
http://dx.doi.org/10.1001/jamaneurol.2015.67DOI Listing
June 2015

Defining amyloid pathology in persons with and without dementia syndromes: making the right diagnosis.

JAMA 2015 May;313(19):1913-4

University of Texas Southwestern Medical Center at Dallas, Department of Neurology and the Alzheimer's Disease Center, Dallas2Editor, JAMA Neurology.

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http://dx.doi.org/10.1001/jama.2015.5361DOI Listing
May 2015

A noninflammatory immune response in aged DNA Aβ42-immunized mice supports its safety for possible use as immunotherapy in AD patients.

Neurobiol Aging 2015 Mar 12;36(3):1274-81. Epub 2014 Dec 12.

Department of Neurology and Neurotherapeutics, Alzheimer's Disease Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389281PMC
March 2015

Rarity of the Alzheimer disease-protective APP A673T variant in the United States.

Authors:
Li-San Wang Adam C Naj Robert R Graham Paul K Crane Brian W Kunkle Carlos Cruchaga Josue D Gonzalez Murcia Lisa Cannon-Albright Clinton T Baldwin Henrik Zetterberg Kaj Blennow Walter A Kukull Kelley M Faber Nicole Schupf Maria C Norton JoAnn T Tschanz Ronald G Munger Christopher D Corcoran Ekaterina Rogaeva Chiao-Feng Lin Beth A Dombroski Laura B Cantwell Amanda Partch Otto Valladares Hakon Hakonarson Peter St George-Hyslop Robert C Green Alison M Goate Tatiana M Foroud Regina M Carney Eric B Larson Timothy W Behrens John S K Kauwe Jonathan L Haines Lindsay A Farrer Margaret A Pericak-Vance Richard Mayeux Gerard D Schellenberg Marilyn S Albert Roger L Albin Liana G Apostolova Steven E Arnold Robert Barber Michael Barmada Lisa L Barnes Thomas G Beach James T Becker Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Steven L Carroll Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Steven T DeKosky F Yesim Demirci Malcolm Dick Dennis W Dickson Ranjan Duara Nilufer Ertekin-Taner Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Jonathan D Glass Neill R Graff-Radford John H Growdon Ronald L Hamilton Kara L Hamilton-Nelson Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun Gyungah Jun M Ilyas Kamboh Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Gei Li Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Constantine G Lyketsos Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee W Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Jill R Murrell John M Olichney Joseph E Parisi William Perry Elaine Peskind Ronald C Petersen Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Howard J Rosen Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Linda J Van Eldik Badri N Vardarajan Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Sarah Wishnek Randall L Woltjer Clinton B Wright Steven G Younkin Chang-En Yu Lei Yu

JAMA Neurol 2015 Feb;72(2):209-16

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1001/jamaneurol.2014.2157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324097PMC
February 2015

Co-stimulation with TNF receptor superfamily 4/25 antibodies enhances in-vivo expansion of CD4+CD25+Foxp3+ T cells (Tregs) in a mouse study for active DNA Aβ42 immunotherapy.

J Neuroimmunol 2015 Jan 10;278:90-9. Epub 2014 Dec 10.

Department of Neurology and Neurotherapeutics, Alzheimer's Disease Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1016/j.jneuroim.2014.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303183PMC
January 2015

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

Authors:
Adam C Naj Gyungah Jun Christiane Reitz Brian W Kunkle William Perry Yo Son Park Gary W Beecham Ruchita A Rajbhandary Kara L Hamilton-Nelson Li-San Wang John S K Kauwe Matthew J Huentelman Amanda J Myers Thomas D Bird Bradley F Boeve Clinton T Baldwin Gail P Jarvik Paul K Crane Ekaterina Rogaeva M Michael Barmada F Yesim Demirci Carlos Cruchaga Patricia L Kramer Nilufer Ertekin-Taner John Hardy Neill R Graff-Radford Robert C Green Eric B Larson Peter H St George-Hyslop Joseph D Buxbaum Denis A Evans Julie A Schneider Kathryn L Lunetta M Ilyas Kamboh Andrew J Saykin Eric M Reiman Philip L De Jager David A Bennett John C Morris Thomas J Montine Alison M Goate Deborah Blacker Debby W Tsuang Hakon Hakonarson Walter A Kukull Tatiana M Foroud Eden R Martin Jonathan L Haines Richard P Mayeux Lindsay A Farrer Gerard D Schellenberg Margaret A Pericak-Vance Marilyn S Albert Roger L Albin Liana G Apostolova Steven E Arnold Robert Barber Lisa L Barnes Thomas G Beach James T Becker Duane Beekly Eileen H Bigio James D Bowen Adam Boxer James R Burke Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Minerva M Carrasquillo Steven L Carroll Helena C Chui David G Clark Jason Corneveaux David H Cribbs Elizabeth A Crocco Charles DeCarli Steven T DeKosky Malcolm Dick Dennis W Dickson Ranjan Duara Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Jonathan D Glass John H Growdon Ronald L Hamilton Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gregory A Jicha Lee-Way Jin Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Chiao-Feng Lin Oscar L Lopez Constantine G Lyketsos Wendy J Mack Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Jill R Murrell John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson Elaine Peskind Ronald C Petersen Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg John M Ringman Erik D Roberson Howard J Rosen Roger N Rosenberg Mary Sano Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Otto Valladares Vivianna M Van Deerlin Linda J Van Eldik Badri N Vardarajan Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Sarah Wishnek Randall L Woltjer Clinton B Wright Steven G Younkin Chang-En Yu Lei Yu

JAMA Neurol 2014 Nov;71(11):1394-404

Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois.

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http://dx.doi.org/10.1001/jamaneurol.2014.1491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314944PMC
November 2014

Effect of leukocyte telomere length on total and regional brain volumes in a large population-based cohort.

JAMA Neurol 2014 Oct;71(10):1247-54

Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas3Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.

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http://dx.doi.org/10.1001/jamaneurol.2014.1926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479062PMC
October 2014

Advancing neurotherapeutics in the 21st century.

JAMA 2014 Apr 23-30;311(16):1620-1

University of California at Los Angeles, Neurology, Los Angeles, California4Associate Editor, JAMA.

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http://dx.doi.org/10.1001/jama.2014.4084DOI Listing
May 2014

Anti-amyloid beta to tau - based immunization: Developments in immunotherapy for Alzheimer disease.

Immunotargets Ther 2013 Aug;2013(2):105-114

Department of Neurology and Neurotherapeutics, Alzheimer's Disease Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.2147/ITT.S31428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051350PMC
August 2013

The new look of JAMA Neurology!

JAMA Neurol 2013 Jul;70(7):827

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http://dx.doi.org/10.1001/jamaneurol.2013.3566DOI Listing
July 2013

From the genetic code to neuromics.

JAMA Neurol 2013 Jun;70(6):684-5

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http://dx.doi.org/10.1001/jamaneurol.2013.2854DOI Listing
June 2013

DNA Aβ42 vaccination as possible alternative immunotherapy for Alzheimer disease.

JAMA Neurol 2013 Jun;70(6):772-3

Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9036, USA.

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http://dx.doi.org/10.1001/jamaneurol.2013.1502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077322PMC
June 2013

Advances in the development of vaccines for Alzheimer's disease.

Discov Med 2013 May;15(84):319-26

Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696351PMC
May 2013

A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease.

J Neuroimmunol 2013 Jan 1;254(1-2):63-8. Epub 2012 Oct 1.

Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, United States.

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http://dx.doi.org/10.1016/j.jneuroim.2012.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084825PMC
January 2013

Active DNA Aβ42 vaccination as immunotherapy for Alzheimer disease.

Transl Neurosci 2012 Dec;3(4):307-313

Department of Neurology and Neurotherapeutics, Alzheimer's Disease Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.2478/s13380-012-0037-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670794PMC
December 2012

Novel late-onset Alzheimer disease loci variants associate with brain gene expression.

Authors:
Mariet Allen Fanggeng Zou High Seng Chai Curtis S Younkin Julia Crook V Shane Pankratz Minerva M Carrasquillo Christopher N Rowley Asha A Nair Sumit Middha Sooraj Maharjan Thuy Nguyen Li Ma Kimberly G Malphrus Ryan Palusak Sarah Lincoln Gina Bisceglio Constantin Georgescu Debra Schultz Fariborz Rakhshan Christopher P Kolbert Jin Jen Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner Liana G Apostolova Steven E Arnold Clinton T Baldwin Robert Barber Michael M Barmada Thomas Beach Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Jacqueline Buros Joseph D Buxbaum Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Paul K Crane Carlos Cruchaga Jeffrey L Cummings Philip L De Jager Charles DeCarli Steven T DeKosky F Yesim Demirci Ramon Diaz-Arrastia Malcolm Dick Beth A Dombroski Ranjan Duara William D Ellis Denis Evans Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Tatiana M Foroud Matthew Frosch Douglas R Galasko Paul J Gallins Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass Alison M Goate Robert C Green John H Growdon Hakon Hakonarson Ronald L Hamilton John Hardy Lindy E Harrell Elizabeth Head Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun M Ilyas Kamboh Jason Karlawish Anna Karydas John S K Kauwe Jeffrey A Kaye Nancy Kennedy Ronald Kim Edward H Koo Neil W Kowall Patricia Kramer Walter A Kukull James J Lah Eric B Larson Allan I Levey Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Amanda J Myers Adam C Naj Petra Nowotny Joseph E Parisi Daniel P Perl Elaine Peskind Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Ruchita A Rajbhandary Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Peter St George-Hyslop Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Badri Narayan Vardarajan Harry V Vinters Jean Paul Vonsattel Li-San Wang Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer

Neurology 2012 Jul 20;79(3):221-8. Epub 2012 Jun 20.

Department of Neuroscience, Biostatistics Unit, Mayo Clinic Florida, Jacksonville, FL, USA.

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http://dx.doi.org/10.1212/WNL.0b013e3182605801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398432PMC
July 2012

JAMA Neurology 2013: A New Beginning.

Arch Neurol 2012 Jul;69(7):818

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http://dx.doi.org/10.1001/archneurol.2012.1837DOI Listing
July 2012

The evolution of academic neurology: new information will bring new meaning.

Arch Neurol 2012 Mar 14;69(3):308-14. Epub 2011 Nov 14.

Department of Neurosciences, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0752, USA.

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http://dx.doi.org/10.1001/archneurol.2011.1858DOI Listing
March 2012

Online first all the time and more continuing medical education credit too!

Arch Neurol 2012 Jan 2;69(1):21. Epub 2012 Jan 2.

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http://dx.doi.org/10.1001/archneurol.2011.2250DOI Listing
January 2012

Treat Alzheimer disease before it is symptomatic.

Arch Neurol 2011 Oct 13;68(10):1237-8. Epub 2011 Jun 13.

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http://dx.doi.org/10.1001/archneurol.2011.135DOI Listing
October 2011

The relationship of cardiovascular risk factors to Alzheimer disease in Choctaw Indians.

Am J Geriatr Psychiatry 2011 May;19(5):423-9

Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390-9129, USA.

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http://dx.doi.org/10.1097/JGP.0b013e3181e89a46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603831PMC
May 2011

Expedited publication initiative.

Arch Neurol 2011 May 10;68(5):563. Epub 2011 Jan 10.

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http://dx.doi.org/10.1001/archneurol.2010.353DOI Listing
May 2011

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Authors:
Adam C Naj Gyungah Jun Gary W Beecham Li-San Wang Badri Narayan Vardarajan Jacqueline Buros Paul J Gallins Joseph D Buxbaum Gail P Jarvik Paul K Crane Eric B Larson Thomas D Bird Bradley F Boeve Neill R Graff-Radford Philip L De Jager Denis Evans Julie A Schneider Minerva M Carrasquillo Nilufer Ertekin-Taner Steven G Younkin Carlos Cruchaga John S K Kauwe Petra Nowotny Patricia Kramer John Hardy Matthew J Huentelman Amanda J Myers Michael M Barmada F Yesim Demirci Clinton T Baldwin Robert C Green Ekaterina Rogaeva Peter St George-Hyslop Steven E Arnold Robert Barber Thomas Beach Eileen H Bigio James D Bowen Adam Boxer James R Burke Nigel J Cairns Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Jeffrey L Cummings Charles DeCarli Steven T DeKosky Ramon Diaz-Arrastia Malcolm Dick Dennis W Dickson William G Ellis Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass John H Growdon Ronald L Hamilton Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gregory A Jicha Lee-Way Jin Nancy Johnson Jason Karlawish Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall James J Lah Allan I Levey Andrew P Lieberman Oscar L Lopez Wendy J Mack Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Joseph E Parisi Daniel P Perl Elaine Peskind Ronald C Petersen Wayne W Poon Joseph F Quinn Ruchita A Rajbhandary Murray Raskind Barry Reisberg John M Ringman Erik D Roberson Roger N Rosenberg Mary Sano Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer Laura B Cantwell Beth A Dombroski Duane Beekly Kathryn L Lunetta Eden R Martin M Ilyas Kamboh Andrew J Saykin Eric M Reiman David A Bennett John C Morris Thomas J Montine Alison M Goate Deborah Blacker Debby W Tsuang Hakon Hakonarson Walter A Kukull Tatiana M Foroud Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg

Nat Genet 2011 May 3;43(5):436-41. Epub 2011 Apr 3.

The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.

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http://dx.doi.org/10.1038/ng.801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090745PMC
May 2011

[Aβ42 gene vaccine for prevention and treatment of Alzheimer's disease].

Rinsho Shinkeigaku 2010 Nov;50(11):838

University of Texas Southwestern Medical Center at Dallas, Texas 75390, USA.

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November 2010

Translational research in neurology and neuroscience 2010-2011.

Arch Neurol 2010 Oct;67(10):1176

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http://dx.doi.org/10.1001/archneurol.2010.247DOI Listing
October 2010

Analysis of three plasmid systems for use in DNA A beta 42 immunization as therapy for Alzheimer's disease.

Vaccine 2010 Jul 4;28(32):5280-7. Epub 2010 Jun 4.

Alzheimer's Disease Center, Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9036, USA.

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http://dx.doi.org/10.1016/j.vaccine.2010.05.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926979PMC
July 2010

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

Authors:
Vivianna M Van Deerlin Patrick M A Sleiman Maria Martinez-Lage Alice Chen-Plotkin Li-San Wang Neill R Graff-Radford Dennis W Dickson Rosa Rademakers Bradley F Boeve Murray Grossman Steven E Arnold David M A Mann Stuart M Pickering-Brown Harro Seelaar Peter Heutink John C van Swieten Jill R Murrell Bernardino Ghetti Salvatore Spina Jordan Grafman John Hodges Maria Grazia Spillantini Sid Gilman Andrew P Lieberman Jeffrey A Kaye Randall L Woltjer Eileen H Bigio Marsel Mesulam Safa Al-Sarraj Claire Troakes Roger N Rosenberg Charles L White Isidro Ferrer Albert Lladó Manuela Neumann Hans A Kretzschmar Christine Marie Hulette Kathleen A Welsh-Bohmer Bruce L Miller Ainhoa Alzualde Adolfo Lopez de Munain Ann C McKee Marla Gearing Allan I Levey James J Lah John Hardy Jonathan D Rohrer Tammaryn Lashley Ian R A Mackenzie Howard H Feldman Ronald L Hamilton Steven T Dekosky Julie van der Zee Samir Kumar-Singh Christine Van Broeckhoven Richard Mayeux Jean Paul G Vonsattel Juan C Troncoso Jillian J Kril John B J Kwok Glenda M Halliday Thomas D Bird Paul G Ince Pamela J Shaw Nigel J Cairns John C Morris Catriona Ann McLean Charles DeCarli William G Ellis Stefanie H Freeman Matthew P Frosch John H Growdon Daniel P Perl Mary Sano David A Bennett Julie A Schneider Thomas G Beach Eric M Reiman Bryan K Woodruff Jeffrey Cummings Harry V Vinters Carol A Miller Helena C Chui Irina Alafuzoff Päivi Hartikainen Danielle Seilhean Douglas Galasko Eliezer Masliah Carl W Cotman M Teresa Tuñón M Cristina Caballero Martínez David G Munoz Steven L Carroll Daniel Marson Peter F Riederer Nenad Bogdanovic Gerard D Schellenberg Hakon Hakonarson John Q Trojanowski Virginia M-Y Lee

Nat Genet 2010 Mar 14;42(3):234-9. Epub 2010 Feb 14.

[1] Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. [2] These authors contributed equally to this work.

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http://dx.doi.org/10.1038/ng.536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828525PMC
March 2010

Notice of incomplete referencing.

Arch Neurol 2009 Oct;66(10):1299-300; author reply 300

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http://dx.doi.org/10.1001/archneurol.2009.215DOI Listing
October 2009

Unreported financial disclosure.

Arch Neurol 2009 Oct;66(10):1300

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http://dx.doi.org/10.1001/archneurol.2009.226DOI Listing
October 2009

DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model.

JAMA 2009 Oct;302(16):1796-802

Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9108, USA.

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http://dx.doi.org/10.1001/jama.2009.1547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896011PMC
October 2009

Exercised against dementia.

Arch Neurol 2009 Mar;66(3):311-2

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http://dx.doi.org/10.1001/archneurol.2008.577DOI Listing
March 2009

Consciousness, coma, and brain death--2009.

JAMA 2009 Mar;301(11):1172-4

Department of Neurology and Alzheimer's Disease Center, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1001/jama.2009.224DOI Listing
March 2009

200 years after Darwin.

Arch Neurol 2009 Feb;66(2):153-5

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http://dx.doi.org/10.1001/archneurol.2008.580DOI Listing
February 2009

200 years after Darwin.

JAMA 2009 Feb;301(6):660-2

Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390-9108, USA.

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http://dx.doi.org/10.1001/jama.2009.80DOI Listing
February 2009

Atherosclerosis risk factors in American Indians with Alzheimer disease: preliminary findings.

Alzheimer Dis Assoc Disord 2008 Jul-Sep;22(3):245-8

Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1097/WAD.0b013e318169d701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176329PMC
November 2008

Neuromics.

Arch Neurol 2008 Mar;65(3):304

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http://dx.doi.org/10.1001/archneur.65.3.304DOI Listing
March 2008

Neuromics and neurological disease.

Arch Neurol 2008 Mar;65(3):307-8

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http://dx.doi.org/10.1001/archneur.65.3.307DOI Listing
March 2008

Genome-wide association studies in Alzheimer disease.

Arch Neurol 2008 Mar;65(3):329-34

Department of Epidemiology, The University of Texas School of Public Health, 1200 Herman Pressler, RAS-E629, Houston, TX 77030, USA.

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http://dx.doi.org/10.1001/archneur.65.3.329DOI Listing
March 2008

Prion proteins: physiological functions and role in neurological disorders.

J Neurol Sci 2008 Jan 17;264(1-2):1-8. Epub 2007 Aug 17.

Department of Neurology, University of Texas Southwestern Medical Center at Dallas, TX 75390-9036, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S0022510X0700400
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http://dx.doi.org/10.1016/j.jns.2007.06.019DOI Listing
January 2008

Abeta42 gene vaccine prevents Abeta42 deposition in brain of double transgenic mice.

J Neurol Sci 2007 Sep 15;260(1-2):204-13. Epub 2007 Jun 15.

Alzheimer's Disease Center, Department of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9036, USA.

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http://dx.doi.org/10.1016/j.jns.2007.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587214PMC
September 2007

Treating Alzheimer disease: Time matters.

Arch Neurol 2006 Jul;63(7):926-8

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http://dx.doi.org/10.1001/archneur.63.7.926DOI Listing
July 2006

Time will be of the essence in treating Alzheimer disease.

JAMA 2006 Jul;296(3):327-9

Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1001/jama.296.3.327DOI Listing
July 2006

Increased risk for heterozygotes in recessive Parkinson disease.

Arch Neurol 2006 Jun;63(6):807-8

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http://dx.doi.org/10.1001/archneur.63.6.807DOI Listing
June 2006

Abeta42 gene vaccination reduces brain amyloid plaque burden in transgenic mice.

J Neurol Sci 2006 May 6;244(1-2):151-8. Epub 2006 Mar 6.

Alzheimer's Diseases Center, Department of Neurology, University of Texas Southwestern Medical Center, 5323, Harry Hines, Dallas, 75390-9036, USA.

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http://dx.doi.org/10.1016/j.jns.2006.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1531642PMC
May 2006

Performance of elderly Native Americans and Caucasians on the CERAD Neuropsychological Battery.

Alzheimer Dis Assoc Disord 2005 Apr-Jun;19(2):74-8

Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8846, USA.

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January 2006

Platelet amyloid precursor protein processing: a bio-marker for Alzheimer's disease.

J Neurol Sci 2006 Jan 26;240(1-2):53-8. Epub 2005 Oct 26.

Department of Neurology, University of Texas Southwestern Medical Center at Dallas, United States.

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http://dx.doi.org/10.1016/j.jns.2005.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479090PMC
January 2006

FMRI of working memory in patients with mild cognitive impairment and probable Alzheimer's disease.

Eur Radiol 2006 Jan 14;16(1):193-206. Epub 2005 Jun 14.

Department of Radiology and Alzheimer's Disease Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-8896, USA.

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http://dx.doi.org/10.1007/s00330-005-2794-xDOI Listing
January 2006

New presenilin 1 mutation with Alzheimer disease and Lewy bodies.

Arch Neurol 2005 Dec;62(12):1808

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http://dx.doi.org/10.1001/archneur.62.12.1808DOI Listing
December 2005

Translational research on the way to effective therapy for Alzheimer disease.

Arch Gen Psychiatry 2005 Nov;62(11):1186-92

Department of Neurology and the Alzheimer's Disease Center, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9036, USA.

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http://dx.doi.org/10.1001/archpsyc.62.11.1186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479851PMC
November 2005

Immunotherapy for Alzheimer disease: the promise and the problem.

Arch Neurol 2005 Oct;62(10):1506-7

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http://dx.doi.org/10.1001/archneur.62.10.1506DOI Listing
October 2005

Gene vaccination to bias the immune response to amyloid-beta peptide as therapy for Alzheimer disease.

Arch Neurol 2004 Dec;61(12):1859-64

Center for Biomedical Inventions, Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, 5232 Harry Hines Boulevard, Dallas, TX 75390-9036, USA.

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http://dx.doi.org/10.1001/archneur.61.12.1859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1482312PMC
December 2004

West Nile virus encephalomyelitis in transplant recipients.

Arch Neurol 2004 Aug;61(8):1181

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http://dx.doi.org/10.1001/archneur.61.8.1181DOI Listing
August 2004

Genes for movement.

Arch Neurol 2004 Aug;61(8):1182

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http://dx.doi.org/10.1001/archneur.61.8.1182DOI Listing
August 2004

West Nile virus encephalomyelitis in transplant recipients.

JAMA 2004 Aug;292(7):859-60

Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1001/jama.292.7.859DOI Listing
August 2004

Genes for movement.

Arch Neurol 2004 Jul;61(7):1006

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http://dx.doi.org/10.1001/archneur.61.7.1006DOI Listing
July 2004

Positive potential of fetal nigral implants for Parkinson disease.

Arch Neurol 2004 Jun;61(6):837-8

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http://dx.doi.org/10.1001/archneur.61.6.837DOI Listing
June 2004

Can alzheimer's disease and dementias with Lewy bodies be distinguished clinically?

J Geriatr Psychiatry Neurol 2003 Dec;16(4):245-50

Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas 75390-9070, USA.

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http://dx.doi.org/10.1177/0891988703258671DOI Listing
December 2003

Metal chelation therapy for Alzheimer disease.

Arch Neurol 2003 Dec;60(12):1678-9

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http://dx.doi.org/10.1001/archneur.60.12.1678DOI Listing
December 2003

Comparison of Alzheimer's disease in Native Americans and Whites.

Int Psychogeriatr 2003 Dec;15(4):367-75

Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9070, USA.

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December 2003

Pain 2003.

Arch Neurol 2003 Nov;60(11):1520

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http://dx.doi.org/10.1001/archneur.60.11.1520DOI Listing
November 2003

Comment on "American Indians/Alaska natives and dementia".

Alzheimer Dis Assoc Disord 2003 Apr-Jun;17(2):132; author reply 132

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August 2003

Evolutionary time and human memory.

JAMA 2002 Dec;288(23):3045-7

Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1001/jama.288.23.3045DOI Listing
December 2002

Time and memory.

Arch Neurol 2002 Nov;59(11):1699-700

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November 2002

Mitochondrial therapy for Parkinson disease.

Arch Neurol 2002 Oct;59(10):1523

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October 2002

Explaining the cause of the amyloid burden in Alzheimer disease.

Arch Neurol 2002 Sep;59(9):1367-8

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September 2002