Roger N Gunn - Hammersmith Hospital - Professor of Molecular Neuroimaging

Roger N Gunn

Hammersmith Hospital

Professor of Molecular Neuroimaging

London | United Kingdom

Main Specialties: Radiology-Diagnostic

Additional Specialties: Imaging

Roger N Gunn - Hammersmith Hospital - Professor of Molecular Neuroimaging

Roger N Gunn

Introduction

Primary Affiliation: Hammersmith Hospital - London , United Kingdom

Specialties:

Additional Specialties:

Publications

78Publications

1308Reads

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2004PubMed Central Citations

The simplified reference tissue model: model assumption violations and their impact on binding potential.

J Cereb Blood Flow Metab 2015 Feb 26;35(2):304-11. Epub 2014 Nov 26.

1] Imanova, Centre for Imaging Sciences, Imperial College London, Hammersmith Hospital, London, UK [2] Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK [3] Department of Engineering Science, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/jcbfm.2014.202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426748PMC
February 2015
15 Reads
15 Citations
5.410 Impact Factor

Amphetamine induced endogenous opioid release in the human brain detected with [¹¹C]carfentanil PET: replication in an independent cohort.

Int J Neuropsychopharmacol 2014 Dec 7;17(12):2069-74. Epub 2014 May 7.

Division of Brain Science, Faculty of Medicine,Centre for Neuropsychopharmacology, Imperial College London,UK.

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http://dx.doi.org/10.1017/S1461145714000704DOI Listing
December 2014
31 Reads
13 Citations
4.010 Impact Factor

PET neuroimaging: the elephant unpacks his trunk: comment on Cumming: "PET neuroimaging: the white elephant packs his trunk?".

Neuroimage 2014 Jul 31;94:408-410. Epub 2013 Dec 31.

Imanova, Centre for Imaging Sciences, London, UK; Centre for Neuroimaging Sciences, Institute of Psychiatry, King's College, London, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2013.12.042DOI Listing
July 2014
1 Read
6.360 Impact Factor

In Vivo Assessment of Brain White Matter Inflammation in Multiple Sclerosis with (18)F-PBR111 PET.

J Nucl Med 2014 Jul 5;55(7):1112-8. Epub 2014 Jun 5.

Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom Neurosciences, GlaxoSmithKline, Brentford, United Kingdom

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http://dx.doi.org/10.2967/jnumed.113.135129DOI Listing
July 2014
39 Reads
15 Citations
6.160 Impact Factor

PET studies in drug development: Methodological considerations.

Drug Discov Today Technol 2005 ;2(4):311-5

Translational Medicine and Genetics, GlaxoSmithKline, 891-995 Greenford Road, Greenford, Middlesex, UK UB6 7HE.

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http://dx.doi.org/10.1016/j.ddtec.2005.11.003DOI Listing
July 2014
4 Reads
4 Citations

Advances in biomathematical modeling for PET neuroreceptor imaging.

Drug Discov Today Technol 2011 ;8(2-4):e45-51

Imanova Limited, Burlington Danes Building, Imperial College London, Hammersmith Hospital, London, Du Cane Road, W12 0NN, UK.

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http://dx.doi.org/10.1016/j.ddtec.2012.01.001DOI Listing
July 2014
13 Reads

In vivo imaging of cerebral dopamine D3 receptors in alcoholism.

Neuropsychopharmacology 2014 Jun 28;39(7):1703-12. Epub 2014 Jan 28.

Centre for Neuropsychopharmacology, Division of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/npp.2014.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023144PMC
June 2014
20 Reads
20 Citations
7.050 Impact Factor

Determination of [(11)C]PBR28 binding potential in vivo: a first human TSPO blocking study.

J Cereb Blood Flow Metab 2014 Jun 19;34(6):989-94. Epub 2014 Mar 19.

1] Centre for Neuroimaging Sciences, Institute of Psychiatry, King's College London, London, UK [2] Imanova, Centre for Imaging Sciences, London, UK.

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http://dx.doi.org/10.1038/jcbfm.2014.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050243PMC
June 2014
36 Reads
25 Citations
5.410 Impact Factor

Phosphodiesterase 10A PET radioligand development program: from pig to human.

J Nucl Med 2014 Apr 10;55(4):595-601. Epub 2014 Mar 10.

Imanova Ltd., Centre for Imaging Sciences, Hammersmith Hospital, London, United Kingdom.

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http://dx.doi.org/10.2967/jnumed.113.131409DOI Listing
April 2014
39 Reads
5 Citations
6.160 Impact Factor

A generalised spatio-temporal registration framework for dynamic PET data: application to neuroreceptor imaging.

Med Image Comput Comput Assist Interv 2013 ;16(Pt 1):211-8

Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, UK.

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http://link.springer.com/content/pdf/10.1007%2F978-3-642-408
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http://dx.doi.org/10.1007/978-3-642-40811-3_27DOI Listing
February 2014
2 Reads
1 Citation

Spatio-temporal pharmacokinetic model based registration of 4D PET neuroimaging data.

Neuroimage 2014 Jan 28;84:225-35. Epub 2013 Aug 28.

Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, UK; Imanova Limited, Hammersmith Hospital, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2013.08.031DOI Listing
January 2014
35 Reads
1 Citation
6.360 Impact Factor

Quantification of the specific translocator protein signal of 18F-PBR111 in healthy humans: a genetic polymorphism effect on in vivo binding.

J Nucl Med 2013 Nov 26;54(11):1915-23. Epub 2013 Sep 26.

Centre for Imaging Sciences, Imanova, London, United Kingdom.

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http://dx.doi.org/10.2967/jnumed.113.121020DOI Listing
November 2013
55 Reads
18 Citations
6.160 Impact Factor

Non linear mixed effects analysis in PET PK-receptor occupancy studies.

Neuroimage 2013 Aug 18;76:155-66. Epub 2013 Mar 18.

GlaxoSmithKline, Clinical Pharmacology Modelling & Simulation, Stockley Park, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2013.03.006DOI Listing
August 2013
6 Reads
1 Citation
6.360 Impact Factor

Kinetic analysis of drug-target interactions with PET for characterization of pharmacological hysteresis.

J Cereb Blood Flow Metab 2013 May 6;33(5):700-7. Epub 2013 Feb 6.

GlaxoSmithKline, Clinical Imaging Centre, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1038/jcbfm.2012.208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652698PMC
May 2013
22 Reads
2 Citations
5.410 Impact Factor

Mathematical modelling of [¹¹C]-(+)-PHNO human competition studies.

Neuroimage 2013 Mar 30;68:119-32. Epub 2012 Nov 30.

GlaxoSmithKline Clinical Imaging Centre, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2012.11.033DOI Listing
March 2013
19 Reads
15 Citations
6.360 Impact Factor

A non-linear mixed effect modelling approach for metabolite correction of the arterial input function in PET studies.

Neuroimage 2013 Feb 27;66:611-22. Epub 2012 Oct 27.

Department of Information Engineering, University of Padova, Padova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2012.10.048DOI Listing
February 2013
3 Reads
2 Citations
6.360 Impact Factor

Orbitofrontal connectivity with resting-state networks is associated with midbrain dopamine D3 receptor availability.

Cereb Cortex 2012 Dec 19;22(12):2784-93. Epub 2011 Dec 19.

Centre for Neuroscience, Division of Experimental Medicine, Imperial College London, London W12 0NN, UK.

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http://cercor.oxfordjournals.org/content/early/2011/12/19/ce
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http://www.cercor.oxfordjournals.org/cgi/doi/10.1093/cercor/
Publisher Site
http://dx.doi.org/10.1093/cercor/bhr354DOI Listing
December 2012
4 Reads
23 Citations
8.665 Impact Factor

Endogenous opioid release in the human brain reward system induced by acute amphetamine administration.

Biol Psychiatry 2012 Sep 3;72(5):371-7. Epub 2012 Mar 3.

Neuropsychopharmacology Unit, Centre for Pharmacology and Therapeutics, Division of Experimental Medicine, Department of Medicine, Imperial College, London, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2012.01.027DOI Listing
September 2012
17 Reads
27 Citations
10.260 Impact Factor

Affinity and selectivity of [¹¹C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo.

Synapse 2012 Jun 24;66(6):489-500. Epub 2012 Feb 24.

PET Center, Department of Diagnostic Radiology, Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1002/syn.21535DOI Listing
June 2012
11 Reads
32 Citations
2.130 Impact Factor

Combining PET biodistribution and equilibrium dialysis assays to assess the free brain concentration and BBB transport of CNS drugs.

J Cereb Blood Flow Metab 2012 May 25;32(5):874-83. Epub 2012 Jan 25.

GlaxoSmithKline, Clinical Imaging Centre, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1038/jcbfm.2012.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345915PMC
May 2012
8 Reads
7 Citations
5.410 Impact Factor

Identifying improved TSPO PET imaging probes through biomathematics: the impact of multiple TSPO binding sites in vivo.

Neuroimage 2012 Apr 10;60(2):902-10. Epub 2012 Jan 10.

Division of Experimental Medicine, Imperial College London, Hammersmith Hospital, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2011.12.078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314937PMC
April 2012
24 Reads
19 Citations
6.360 Impact Factor

A pharmacokinetic PET study of NK₁ receptor occupancy.

Eur J Nucl Med Mol Imaging 2012 Feb 13;39(2):226-35. Epub 2011 Oct 13.

GlaxoSmithKline, Clinical Pharmacology Modeling & Simulation, Stockley Park, UK.

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http://dx.doi.org/10.1007/s00259-011-1954-2DOI Listing
February 2012
3 Reads
8 Citations
5.383 Impact Factor

Positron emission tomography molecular imaging for drug development.

Br J Clin Pharmacol 2012 Feb;73(2):175-86

GSK Clinical Imaging Centre, GlaxoSmithKline Research and Development Ltd, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1111/j.1365-2125.2011.04085.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269576PMC
February 2012
1 Read
49 Citations
3.880 Impact Factor

An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28.

J Cereb Blood Flow Metab 2012 Jan 19;32(1):1-5. Epub 2011 Oct 19.

Division of Experimental Medicine, Department of Medicine, Imperial College London, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1038/jcbfm.2011.147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323305PMC
January 2012
24 Reads
145 Citations
5.410 Impact Factor

Translational characterization of [11C]GSK931145, a PET ligand for the glycine transporter type 1.

Synapse 2011 Dec 12;65(12):1319-32. Epub 2011 Aug 12.

GlaxoSmithKline, Clinical Imaging Center, Hammersmith Hospital, London, United Kingdom.

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http://dx.doi.org/10.1002/syn.20966DOI Listing
December 2011
18 Reads
11 Citations
2.130 Impact Factor

Characterization of in vivo pharmacological properties and sensitivity to endogenous serotonin of [11C] P943: a positron emission tomography study in Papio anubis.

Synapse 2011 Nov 19;65(11):1119-27. Epub 2011 May 19.

GlaxoSmithKline, Clinical Imaging Centre, London, UK.

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http://dx.doi.org/10.1002/syn.20946DOI Listing
November 2011
26 Reads
8 Citations
2.130 Impact Factor

Radiosynthesis and in vivo evaluation of [(11)C]MP-10 as a positron emission tomography radioligand for phosphodiesterase 10A.

Nucl Med Biol 2011 Aug 30;38(6):875-84. Epub 2011 Mar 30.

GlaxoSmithKline, Clinical Imaging Centre Hammersmith Hospital, London, W12 0NN, UK.

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http://dx.doi.org/10.1016/j.nucmedbio.2011.02.005DOI Listing
August 2011
8 Reads
11 Citations
2.412 Impact Factor

In vivo binding of antipsychotics to D3 and D2 receptors: a PET study in baboons with [11C]-(+)-PHNO.

Neuropsychopharmacology 2011 Mar 22;36(4):887-95. Epub 2010 Dec 22.

Department of Psychiatry, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1038/npp.2010.228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055723PMC
March 2011
30 Reads
15 Citations
7.050 Impact Factor

Imaging dopamine receptors in humans with [11C]-(+)-PHNO: dissection of D3 signal and anatomy.

Neuroimage 2011 Jan 30;54(1):264-77. Epub 2010 Jun 30.

GlaxoSmithKline, Clinical Imaging Centre, Imperial College, London, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2010.06.044DOI Listing
January 2011
31 Reads
106 Citations
6.360 Impact Factor

Mixed-affinity binding in humans with 18-kDa translocator protein ligands.

J Nucl Med 2011 Jan 13;52(1):24-32. Epub 2010 Dec 13.

Division of Experimental Medicine, Imperial College, Hammersmith Hospital, London, United Kingdom.

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http://dx.doi.org/10.2967/jnumed.110.079459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161826PMC
January 2011
31 Reads
80 Citations
6.160 Impact Factor

Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation.

J Cereb Blood Flow Metab 2010 Sep 28;30(9):1608-18. Epub 2010 Apr 28.

Department of Experimental Medicine and Toxicology, Imperial College London, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1038/jcbfm.2010.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949260PMC
September 2010
3 Reads
51 Citations
5.410 Impact Factor

Real-time adaptive sequential design for optimal acquisition of arterial spin labeling MRI data.

Magn Reson Med 2010 Jul;64(1):203-10

Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/mrm.22398DOI Listing
July 2010
17 Reads
5 Citations
3.571 Impact Factor

Evaluation of 11C-GSK189254 as a novel radioligand for the H3 receptor in humans using PET.

J Nucl Med 2010 Jul 16;51(7):1021-9. Epub 2010 Jun 16.

GlaxoSmithKline Clinical Imaging Centre, Imperial College London, Hammersmith Hospital, London, United Kingdom.

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http://jnm.snmjournals.org/content/51/7/1021.full.pdf
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http://jnm.snmjournals.org/cgi/doi/10.2967/jnumed.109.071753
Publisher Site
http://dx.doi.org/10.2967/jnumed.109.071753DOI Listing
July 2010
16 Reads
16 Citations
6.160 Impact Factor

Imaging cortical dopamine D1 receptors using [11C]NNC112 and ketanserin blockade of the 5-HT 2A receptors.

J Cereb Blood Flow Metab 2010 May 23;30(5):985-93. Epub 2009 Dec 23.

Discovery Medicine, Neurosciences Centre of Excellence for Drug Discovery, GlaxoSmithKline, Barcelona, Spain.

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http://dx.doi.org/10.1038/jcbfm.2009.269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949183PMC
May 2010
11 Reads
5 Citations
5.410 Impact Factor

Measuring drug occupancy in the absence of a reference region: the Lassen plot re-visited.

J Cereb Blood Flow Metab 2010 Jan 9;30(1):46-50. Epub 2009 Sep 9.

GlaxoSmithKline, Clinical Imaging Centre, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1038/jcbfm.2009.190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949110PMC
January 2010
2 Reads
59 Citations
5.410 Impact Factor

11C-GSK189254: a selective radioligand for in vivo central nervous system imaging of histamine H3 receptors by PET.

J Nucl Med 2009 Dec 12;50(12):2064-72. Epub 2009 Nov 12.

GlaxoSmithKline, Clinical Imaging Centre, Hammersmith Hospital, London, United Kingdom.

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http://dx.doi.org/10.2967/jnumed.109.062919DOI Listing
December 2009
37 Reads
7 Citations
6.160 Impact Factor

A biomathematical modeling approach to central nervous system radioligand discovery and development.

J Nucl Med 2009 Oct 16;50(10):1715-23. Epub 2009 Sep 16.

Department of Engineering Science, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.2967/jnumed.109.063800DOI Listing
October 2009
3 Reads
13 Citations
6.160 Impact Factor

Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies.

Bioorg Med Chem Lett 2009 Sep 25;19(17):5056-9. Epub 2009 Jul 25.

GlaxoSmithKline Clinical Imaging Centre, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK.

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http://dx.doi.org/10.1016/j.bmcl.2009.07.055DOI Listing
September 2009
24 Reads
5 Citations
2.420 Impact Factor

Within-subject comparison of striatal D2 receptor occupancy measurements using [123I]IBZM SPECT and [11C]Raclopride PET.

Neuroimage 2009 Jun 20;46(2):447-58. Epub 2009 Feb 20.

Psychiatry CPDM, GlaxoSmithKline, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.neuroimage.2009.02.005DOI Listing
June 2009
9 Reads
7 Citations
6.360 Impact Factor

Dynamic positron emission tomography data-driven analysis using sparse Bayesian learning.

IEEE Trans Med Imaging 2008 Sep;27(9):1356-69

Institute of Statistical Science, Academia Sinica, Taipei 11529, Taiwan.

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http://dx.doi.org/10.1109/TMI.2008.922185DOI Listing
September 2008
26 Reads
4 Citations
3.390 Impact Factor

Optimal design of pulsed arterial spin labeling MRI experiments.

Magn Reson Med 2008 Apr;59(4):826-34

Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/mrm.21549DOI Listing
April 2008
4 Reads
8 Citations
3.571 Impact Factor

Modeling sensitization to stimulants in humans: an [11C]raclopride/positron emission tomography study in healthy men.

Arch Gen Psychiatry 2006 Dec;63(12):1386-95

McConnell Brain Imaging Center, Montreal Neurological Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1001/archpsyc.63.12.1386DOI Listing
December 2006
36 Reads
79 Citations
14.480 Impact Factor

Estimation of serotonin transporter parameters with 11C-DASB in healthy humans: reproducibility and comparison of methods.

J Nucl Med 2006 May;47(5):815-26

Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, NY 10032, USA.

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May 2006
4 Reads
27 Citations
6.160 Impact Factor

2-[11C]thymidine positron emission tomography reproducibility in humans.

Clin Cancer Res 2005 Jun;11(12):4341-7

Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-1818DOI Listing
June 2005
6 Reads
1 Citation
8.722 Impact Factor

Wavelet variance components in image space for spatiotemporal neuroimaging data.

Neuroimage 2005 Mar 5;25(1):159-68. Epub 2005 Jan 5.

Institute of Statistical Science, Academia Sinica, 128 Academia Road, Sec 2, Taipei 11529, Taiwan.

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http://dx.doi.org/10.1016/j.neuroimage.2004.10.037DOI Listing
March 2005
8 Reads
6.360 Impact Factor

Statistical maps for EEG dipolar source localization.

IEEE Trans Biomed Eng 2005 Mar;52(3):401-13

Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.

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http://dx.doi.org/10.1109/TBME.2004.841263DOI Listing
March 2005
24 Reads
2.350 Impact Factor

Preferential 5-HT1A autoreceptor occupancy by pindolol is attenuated in depressed patients: effect of treatment or an endophenotype of depression?

Neuropsychopharmacology 2004 Sep;29(9):1688-98

PET Psychiatry, Translational Medicine and Technologies, GlaxoSmithKline, Cambridge, UK.

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http://dx.doi.org/10.1038/sj.npp.1300472DOI Listing
September 2004
2 Reads
5 Citations
7.050 Impact Factor

Parametrically defined cerebral blood vessels as non-invasive blood input functions for brain PET studies.

Phys Med Biol 2004 Mar;49(6):1033-54

Department of Physics and Astronomy, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1088/0031-9155/49/6/013DOI Listing
March 2004
4 Reads
5 Citations
2.761 Impact Factor

Bootstrapped DEPICT for error estimation in PET functional imaging.

Neuroimage 2004 Mar;21(3):1096-104

McConnell Brain Imaging Center, Montréal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.

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http://dx.doi.org/10.1016/j.neuroimage.2003.10.015DOI Listing
March 2004
7 Reads
6.360 Impact Factor

PET quantification of muscarinic cholinergic receptors with [N-11C-methyl]-benztropine and application to studies of propofol-induced unconsciousness in healthy human volunteers.

Synapse 2004 Feb;51(2):91-101

Department of Anesthesiology, McGill University, Montreal, Quebec H3A 1A2, Canada.

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http://dx.doi.org/10.1002/syn.10292DOI Listing
February 2004
20 Reads
3 Citations
2.130 Impact Factor

A bolus/infusion paradigm for the novel NMDA receptor SPET tracer [123I]CNS 1261.

Nucl Med Biol 2004 Feb;31(2):155-64

Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK.

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http://dx.doi.org/10.1016/j.nucmedbio.2003.08.008DOI Listing
February 2004
14 Reads
2 Citations
2.412 Impact Factor

Rank-shaping regularization of exponential spectral analysis for application to functional parametric mapping.

Phys Med Biol 2003 Dec;48(23):3819-41

Hammersmith Imanet, Cyclotron Building, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1088/0031-9155/48/23/002DOI Listing
December 2003
5 Reads
10 Citations
2.761 Impact Factor

Evaluation of NMDA receptors in vivo in schizophrenic patients with [123I]CNS 1261 and SPET: preliminary findings.

Ann N Y Acad Sci 2003 Nov;1003:364-7

Institute of Psychiatry, King's College, London, WC2R 2LS, United Kingdom.

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http://dx.doi.org/10.1196/annals.1300.027DOI Listing
November 2003
16 Reads
1 Citation
4.313 Impact Factor

2-[11C]thymidine positron emission tomography as an indicator of thymidylate synthase inhibition in patients treated with AG337.

J Natl Cancer Inst 2003 May;95(9):675-82

Imperial College School of Medicine, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1093/jnci/95.9.675DOI Listing
May 2003
8 Reads
12 Citations
12.583 Impact Factor

Positron emission tomography compartmental models: a basis pursuit strategy for kinetic modeling.

J Cereb Blood Flow Metab 2002 Dec;22(12):1425-39

McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, 3801 University St., Montreal, Quebec, Canada.

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http://dx.doi.org/10.1097/01.wcb.0000045042.03034.42DOI Listing
December 2002
28 Reads
46 Citations
5.410 Impact Factor

Assessment of proliferation in vivo using 2-[(11)C]thymidine positron emission tomography in advanced intra-abdominal malignancies.

Cancer Res 2002 Oct;62(20):5698-702

Department of Cancer Medicine, Imperial College School of Medicine, Hammersmith Hospital, London W12 0HS, United Kingdom.

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October 2002
6 Reads
7 Citations
9.330 Impact Factor

Evaluation of EMD 128 130 occupancy of the 5-HT1A and the D2 receptor: a human PET study with [11C]WAY-100635 and [11C]raclopride.

J Psychopharmacol 2002 Sep;16(3):195-9

MRC Cyclotron Unit, Hammersmith Hospital, Imperial College School of Medicine, London, UK.

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http://dx.doi.org/10.1177/026988110201600301DOI Listing
September 2002
10 Reads
4 Citations
3.593 Impact Factor

Positron emission tomography partial volume correction: estimation and algorithms.

J Cereb Blood Flow Metab 2002 Aug;22(8):1019-34

McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Quebec, Canada.

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http://dx.doi.org/10.1097/00004647-200208000-00014DOI Listing
August 2002
28 Reads
29 Citations
5.410 Impact Factor

A database of [(11)C]WAY-100635 binding to 5-HT(1A) receptors in normal male volunteers: normative data and relationship to methodological, demographic, physiological, and behavioral variables.

Neuroimage 2002 Mar;15(3):620-32

MRC Cyclotron Unit, Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine, Hammersmith Hospital, London W12 0NN, United Kingdom.

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http://dx.doi.org/10.1006/nimg.2001.0984DOI Listing
March 2002
4 Reads
29 Citations
6.360 Impact Factor

The PET radioligand [carbonyl-(11)C]desmethyl-WAY-100635 binds to 5-HT(1A) receptors and provides a higher radioactive signal than [carbonyl-(11)C]WAY-100635 in the human brain.

J Nucl Med 2002 Mar;43(3):292-303

Psychiatry Section, Department of Clinical Neuroscience, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden.

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March 2002
2 Reads
7 Citations
6.160 Impact Factor

Top co-authors

Eugenii A Rabiner
Eugenii A Rabiner

Institute of Psychiatry

43
Marc Laruelle
Marc Laruelle

Columbia University College of Physicians and Surgeons

20
Vincent J Cunningham
Vincent J Cunningham

School of Medical Sciences

17
Graham E Searle
Graham E Searle

Hammersmith Hospital

16
Mark Slifstein
Mark Slifstein

Columbia University College of Physicians and Surgeons

11
Christophe Plisson
Christophe Plisson

Emory University

9
Paul M Matthews
Paul M Matthews

Imperial College London

9
Qi Guo
Qi Guo

Tianjin Medical University

8
Christine A Parker
Christine A Parker

Imperial College London

8
Cristian A Salinas
Cristian A Salinas

Hammersmith Hospital

8