Roger J Hajjar

Roger J Hajjar

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Roger J Hajjar

Publications by authors named "Roger J Hajjar"

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Surgical and physiological challenges in the development of left and right heart failure in rat models.

Heart Fail Rev 2019 Sep;24(5):759-777

Cardiovascular Research Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai, 1470 Madison Ave., Box 1030, New York, NY, 10029-6574, USA.

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http://dx.doi.org/10.1007/s10741-019-09783-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698228PMC
September 2019

MicroRNA-25 upregulation protects spinal cords, yet is bad for the heart: The dark side of noncoding RNAS.

J Thorac Cardiovasc Surg 2019 Sep 16;158(3):e87-e88. Epub 2019 Apr 16.

Department of Cardiology, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1016/j.jtcvs.2019.03.054DOI Listing
September 2019

Allele-Specific Silencing Ameliorates Restrictive Cardiomyopathy Attributable to a Human Myosin Regulatory Light Chain Mutation.

Circulation 2019 Aug 18;140(9):765-778. Epub 2019 Jul 18.

Division of Cardiovascular Medicine (K.Z.-R., A.D., P.C., G.R., C.S., J.L., T.F., W.N.P., S.S., K.S., N.S., N.J., Y.H., M.T.W., E.A.A.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036965DOI Listing
August 2019

Experimental models of cardiac physiology and pathology.

Heart Fail Rev 2019 Jul;24(4):601-615

Icahn School of Medicine at Mount Sinai, New York, USA.

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http://dx.doi.org/10.1007/s10741-019-09769-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561792PMC
July 2019

Animal model of left atrial thrombus in congestive heart failure in rats.

Am J Physiol Heart Circ Physiol 2019 Jul 10;317(1):H63-H72. Epub 2019 May 10.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai , New York, New York.

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http://dx.doi.org/10.1152/ajpheart.00086.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692738PMC
July 2019

Sarco/Endoplasmic Reticulum Ca-ATPase is a more effective calcium remover than Sodium-Calcium Exchanger in human embryonic stem cell-derived cardiomyocytes.

Am J Physiol Heart Circ Physiol 2019 Jul 26. Epub 2019 Jul 26.

Ming Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Hong Kong.

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http://dx.doi.org/10.1152/ajpheart.00540.2018DOI Listing
July 2019

CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy.

Int J Mol Sci 2019 May 8;20(9). Epub 2019 May 8.

Department of Physiology and Biophysics, College of Medicine, Howard University, Washington, DC 20060, USA.

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http://dx.doi.org/10.3390/ijms20092267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539363PMC
May 2019

Speckle-Tracking Echocardiographic Strain Analysis Reliably Estimates Degree of Acute LV Unloading During Mechanical LV Support by Impella.

J Cardiovasc Transl Res 2019 Apr 29;12(2):135-141. Epub 2018 May 29.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1030, New York, NY, 10029-6574, USA.

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http://dx.doi.org/10.1007/s12265-018-9812-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692910PMC
April 2019

Role of the PRC2-Six1-miR-25 signaling axis in heart failure.

J Mol Cell Cardiol 2019 Apr 13;129:58-68. Epub 2019 Feb 13.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.01.017DOI Listing
April 2019

Child Health Promotion in Underserved Communities: The FAMILIA Trial.

J Am Coll Cardiol 2019 Apr;73(16):2011-2021

Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07351097193369
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http://dx.doi.org/10.1016/j.jacc.2019.01.057DOI Listing
April 2019

Ischemic Model of Heart Failure in Rats and Mice.

Methods Mol Biol 2018 ;1816:175-182

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8597-5_13DOI Listing
March 2019

Conventional Method of Transverse Aortic Constriction in Mice.

Methods Mol Biol 2018 ;1816:183-193

Department of Cardiology/Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8597-5_14DOI Listing
March 2019

Characterization of the Differential Progression of Left Ventricular Remodeling in a Rat Model of Pressure Overload Induced Heart Failure. Does Clip Size Matter?

Methods Mol Biol 2018 ;1816:195-206

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8597-5_15DOI Listing
March 2019

Pulmonary Artery Hypertension Model in Rats by Monocrotaline Administration.

Methods Mol Biol 2018 ;1816:233-241

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8597-5_18DOI Listing
March 2019

The Sugen 5416/Hypoxia Mouse Model of Pulmonary Arterial Hypertension.

Methods Mol Biol 2018 ;1816:243-252

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8597-5_19DOI Listing
March 2019

A Pig Model of Myocardial Infarction: Catheter-Based Approaches.

Methods Mol Biol 2018 ;1816:281-294

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8597-5_22DOI Listing
March 2019

Swine Model of Mitral Regurgitation Induced Heart Failure.

Methods Mol Biol 2018 ;1816:327-335

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8597-5_25DOI Listing
March 2019

Chronic Pulmonary Artery Embolization Models in Large Animals.

Methods Mol Biol 2018 ;1816:353-366

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8597-5_28DOI Listing
March 2019

Modeling Pulmonary Hypertension: A Pig Model of Postcapillary Pulmonary Hypertension.

Methods Mol Biol 2018 ;1816:367-383

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-4939-8597-5_29DOI Listing
March 2019

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats.

J Vis Exp 2019 Mar 8(145). Epub 2019 Mar 8.

Cardiovascular Research Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai;

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https://www.jove.com/video/59050/the-left-pneumonectomy-comb
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http://dx.doi.org/10.3791/59050DOI Listing
March 2019

Lentiviral-Mediated Interleukin-10 Gene Therapy for Lung Transplantation.

J Thorac Cardiovasc Surg 2019 Feb;157(2):817-818

Department of Cardiology, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1016/j.jtcvs.2018.07.052DOI Listing
February 2019

Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer.

J Cardiovasc Dev Dis 2019 Feb 15;6(1). Epub 2019 Feb 15.

Cardiovascular Research Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.3390/jcdd6010008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462990PMC
February 2019

Enhancing atrial-specific gene expression using a calsequestrin cis-regulatory module 4 with a sarcolipin promoter.

J Gene Med 2018 12 4;20(12):e3060. Epub 2018 Dec 4.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1002/jgm.3060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519042PMC
December 2018

PLN Foundation.

Circ Res 2018 12;123(12):1276-1278

Department of Cardiology, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York (R.J.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.118.314014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363126PMC
December 2018

A role for calcium in resistin transcriptional activation in diabetic hearts.

Sci Rep 2018 10 23;8(1):15633. Epub 2018 Oct 23.

Cardiovascular Research Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, 10029, USA.

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http://www.nature.com/articles/s41598-018-34112-4
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http://dx.doi.org/10.1038/s41598-018-34112-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199245PMC
October 2018

Of Mice and Men.

Circ Res 2018 10;123(10):1109-1111

From the Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.313990DOI Listing
October 2018

Pharmacological inhibition of the mitochondrial NADPH oxidase 4/PKCα/Gal-3 pathway reduces left ventricular fibrosis following myocardial infarction.

Transl Res 2018 09 23;199:4-23. Epub 2018 Apr 23.

Cardiology Department, Clinic and Universitary Hospital Virgen de la Arrixaca, Murcia, Spain; CIBER in Cardiovascular Diseases (CIBERCV), Madrid, Spain.

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http://dx.doi.org/10.1016/j.trsl.2018.04.004DOI Listing
September 2018

Direct measurement of left atrial and pulmonary artery pressure in rats with pulmonary hypertension.

J Thorac Cardiovasc Surg 2018 09;156(3):1161-1163

Cardiovascular Research Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1016/j.jtcvs.2018.05.026DOI Listing
September 2018

Technique of Complete Heart Isolation with Continuous Cardiac Perfusion During Cardiopulmonary Bypass: New Opportunities for Gene Therapy.

J Extra Corpor Technol 2018 09;50(3):193-198

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146280PMC
September 2018

Mitral Valve Prolapse: A Disease of Valve and Ventricle.

J Am Coll Cardiol 2018 08;72(8):835-837

Cardiovascular Research Center, Mount Sinai Medical School, New York, New York.

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http://dx.doi.org/10.1016/j.jacc.2018.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168064PMC
August 2018

Human Cardiac Gene Therapy.

Circ Res 2018 08;123(5):601-613

From the Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1161/CIRCRESAHA.118.311587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390977PMC
August 2018

Highlighting the Field of Cardiovascular Regenerative Medicine.

Mol Ther 2018 07 19;26(7):1595. Epub 2018 Jun 19.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036328PMC
July 2018

Coronary capillary blood flow in a rat model of congestive heart failure.

J Appl Physiol (1985) 2018 03 19;124(3):632-640. Epub 2017 Oct 19.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai , New York, New York.

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http://dx.doi.org/10.1152/japplphysiol.00741.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899272PMC
March 2018

Stem cell therapy for acute myocardial infarction: on the horizon or still a dream?

Coron Artery Dis 2018 03;29(2):89-91

Icahn School of Medicine at Mount Sinai, Cardiovascular Research Center, New York, New York, USA.

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http://dx.doi.org/10.1097/MCA.0000000000000589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796866PMC
March 2018

miR-25 Tough Decoy Enhances Cardiac Function in Heart Failure.

Mol Ther 2018 03 26;26(3):718-729. Epub 2017 Nov 26.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2017.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910658PMC
March 2018

Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility.

Circ Res 2018 03 15;122(7):933-944. Epub 2018 Feb 15.

From the Cardiovascular Research Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY (J.M., D.K.C., P.A.G., P.M., J.F.M., S.I.S., F.S., S.S., R.J.H., K.D.C.); and Interdisciplinary Stem Cell Institute, Department of Cardiology, University of Miami Miller School of Medicine, Miami, FL (J.M.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.118.312420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986183PMC
March 2018

Echocardiographic and hemodynamic assessment for predicting early clinical events in severe acute mitral regurgitation.

Int J Cardiovasc Imaging 2018 Feb 22;34(2):171-175. Epub 2017 Jul 22.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1030, New York, NY, 10029-6574, USA.

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http://dx.doi.org/10.1007/s10554-017-1215-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885285PMC
February 2018

Reduced longitudinal contraction is associated with ischemic mitral regurgitation after posterior MI.

Am J Physiol Heart Circ Physiol 2018 02 3;314(2):H322-H329. Epub 2017 Nov 3.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai , New York, New York.

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http://dx.doi.org/10.1152/ajpheart.00546.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867658PMC
February 2018

Myocardial Cannabinoid Receptor Imaging in Obesity.

JACC Cardiovasc Imaging 2018 02;11(2 Pt 2):333-335

Icahn School of Medicine at Mount Sinai, Cardiovascular Research Center, New York, New York.

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http://dx.doi.org/10.1016/j.jcmg.2017.12.001DOI Listing
February 2018

Current Methods in Cardiac Gene Therapy: Overview.

Methods Mol Biol 2017 ;1521:3-14

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1030, New York, NY, 10029-6574, USA.

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http://dx.doi.org/10.1007/978-1-4939-6588-5_1DOI Listing
January 2018

Generation of Efficient miRNA Inhibitors Using Tough Decoy Constructs.

Methods Mol Biol 2017 ;1521:41-53

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, Box 1030, New York, NY, 10029-6574, USA.

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http://dx.doi.org/10.1007/978-1-4939-6588-5_3DOI Listing
January 2018

Gene Transfer in Cardiomyocytes Derived from ES and iPS Cells.

Methods Mol Biol 2017 ;1521:183-193

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, Box 1030, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/978-1-4939-6588-5_12DOI Listing
January 2018

Gene Transfer to Rodent Hearts In Vivo.

Methods Mol Biol 2017 ;1521:195-204

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1030, New York, NY, 10029-6574, USA.

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http://dx.doi.org/10.1007/978-1-4939-6588-5_13DOI Listing
January 2018

Cardiac Gene Delivery in Large Animal Models: Antegrade Techniques.

Methods Mol Biol 2017 ;1521:227-235

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1030, New York, NY, 10029-6574, USA.

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http://dx.doi.org/10.1007/978-1-4939-6588-5_16DOI Listing
January 2018

Direct Myocardial Injection of Vectors.

Methods Mol Biol 2017 ;1521:237-248

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1030, New York, NY, 10029-6574, USA.

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http://dx.doi.org/10.1007/978-1-4939-6588-5_17DOI Listing
January 2018

Inhaled Gene Transfer for Pulmonary Circulation.

Methods Mol Biol 2017 ;1521:339-349

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, #1030, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/978-1-4939-6588-5_24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019269PMC
January 2018

SDF-1 induces TNF-mediated apoptosis in cardiac myocytes.

Apoptosis 2018 01;23(1):79-91

Department of Physiology and Biophysics, Howard University College of Medicine, 520 W Street, NW, Suite 2420, Washington, DC, 20059, USA.

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http://dx.doi.org/10.1007/s10495-017-1438-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019273PMC
January 2018

Pulmonary hypertension arising from left heart disease causes intrapulmonary venous arterialization in rats.

J Thorac Cardiovasc Surg 2018 Jan;155(1):281-282

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1016/j.jtcvs.2017.08.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021011PMC
January 2018

Atrial Infarction and Ischemic Mitral Regurgitation Contribute to Post-MI Remodeling of the Left Atrium.

J Am Coll Cardiol 2017 Dec;70(23):2878-2889

Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain; CIBER de enfermedades CardioVasculares, Madrid, Spain; Cardiology Department, IIS-Fundación Jiménez Díaz Hospital, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.10.013DOI Listing
December 2017

Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai Translational Mission.

Circ Res 2017 12;121(12):1316-1319

From the Cardiovascular Institute, Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937980PMC
December 2017

Gene Therapy in Heart Failure.

Handb Exp Pharmacol 2017 ;243:395-421

Icahn School of Medicine at Mount Sinai, Cardiovascular Research Center, New York, NY, USA.

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http://dx.doi.org/10.1007/164_2016_81DOI Listing
October 2017

Heart Isolation Featuring Closed Loop Recirculation: The Gold Standard for Optimum Cardiac Gene Transfer?

Adv Tech Biol Med 2017 6;5(4). Epub 2017 Oct 6.

Cardiovascular Research Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://dx.doi.org/10.4172/2379-1764.1000241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905412PMC
October 2017

Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice.

Nat Commun 2017 10 20;8(1):1068. Epub 2017 Oct 20.

Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA.

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http://dx.doi.org/10.1038/s41467-017-01146-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648780PMC
October 2017

Use of Adeno-Associated Virus Vector for Cardiac Gene Delivery in Large-Animal Surgical Models of Heart Failure.

Hum Gene Ther Clin Dev 2017 09 19;28(3):157-164. Epub 2017 Jul 19.

Cardiovascular Research Center , Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1089/humc.2017.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655838PMC
September 2017

Variability in coronary artery anatomy affects consistency of cardiac damage after myocardial infarction in mice.

Am J Physiol Heart Circ Physiol 2017 Aug 26;313(2):H275-H282. Epub 2017 May 26.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York

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http://dx.doi.org/10.1152/ajpheart.00127.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582916PMC
August 2017

Experimental and Computational Insight Into Human Mesenchymal Stem Cell Paracrine Signaling and Heterocellular Coupling Effects on Cardiac Contractility and Arrhythmogenicity.

Circ Res 2017 Aug 22;121(4):411-423. Epub 2017 Jun 22.

From the Cardiovascular Research Center (J.M., T.J.C., D.K.C., D.S., S.S., R.J.H., K.D.C.), Department of Developmental and Regenerative Biology (D.A.K.), and Department of Pharmacology and Systems Therapeutics (E.A.S.), Icahn School of Medicine at Mount Sinai, New York; Department of Medicine, University of Washington Seattle (B.V.J.); and The Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, FL (J.M.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.310796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899516PMC
August 2017

CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response.

Stem Cell Res 2017 08 8;23:77-86. Epub 2017 Jul 8.

Department of Physiology and Biophysics, College of Medicine, Howard University, Washington, DC 20060, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2017.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859259PMC
August 2017

Cytokine-Like 1 Regulates Cardiac Fibrosis via Modulation of TGF-β Signaling.

PLoS One 2016 11;11(11):e0166480. Epub 2016 Nov 11.

College of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166480PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105950PMC
June 2017

Functional Human Beige Adipocytes From Induced Pluripotent Stem Cells.

Diabetes 2017 06 7;66(6):1470-1478. Epub 2017 Mar 7.

Sorbonne Universités, Université Pierre et Marie Curie, INSERM UMR_S938, Centre de Recherche Saint-Antoine, Institute of Cardiometabolism and Nutrition, Paris, France.

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http://dx.doi.org/10.2337/db16-1107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440013PMC
June 2017

Optimizing Cardiac Delivery of Modified mRNA.

Mol Ther 2017 06 4;25(6):1306-1315. Epub 2017 Apr 4.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2017.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474881PMC
June 2017

Increased afterload following myocardial infarction promotes conduction-dependent arrhythmias that are unmasked by hypokalemia.

JACC Basic Transl Sci 2017 Jun 26;2(3):258-269. Epub 2017 Jun 26.

Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1016/j.jacbts.2017.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547890PMC
June 2017

Angiogenic Mechanisms of Human CD34 Stem Cell Exosomes in the Repair of Ischemic Hindlimb.

Circ Res 2017 Apr 15;120(9):1466-1476. Epub 2017 Mar 15.

From the Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York (P.M., Y.L., D.K., R.J.H., S.S.); Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL (D.K., S.M., T.T., C.E.K., E.K., D.W.L., S.S.); and Caladrius Biosciences, New York (D.W.L.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.310557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420547PMC
April 2017

Synthetic MicroRNAs Stimulate Cardiac Repair.

Circ Res 2017 04;120(8):1222-1223

From the Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York.

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http://dx.doi.org/10.1161/CIRCRESAHA.117.310863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834342PMC
April 2017

Pericardial Fluid Exosomes: A New Material to Treat Cardiovascular Disease.

Mol Ther 2017 03 16;25(3):568-569. Epub 2017 Feb 16.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2017.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363198PMC
March 2017

The Phospholamban Journey 4 Decades After Setting Out for Ithaka.

Circ Res 2017 03;120(5):781-783

From the Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, OH (E.G.K.); and Cardiovascular Research Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY (R.J.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.310007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338645PMC
March 2017

Introducing Genes to the Heart: All About Delivery.

Circ Res 2017 01;120(1):33-35

From the Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.310039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221570PMC
January 2017

Cardiac fibrosis and miR-433.

Ann Transl Med 2016 Dec;4(24):511

College of Life Sciences, Gwangju Institute of Science and Technology, Gwangju, Korea.

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http://dx.doi.org/10.21037/atm.2016.11.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233473PMC
December 2016

Genomic correction of familial cardiomyopathy in human engineered cardiac tissues.

Eur Heart J 2016 Nov 22;37(43):3282-3284. Epub 2016 Jul 22.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, PO Box 1030, New York, NY 10029, USA.

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http://dx.doi.org/10.1093/eurheartj/ehw307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425468PMC
November 2016

The Probability of Inconstancy in Assessment of Cardiac Function Post-Myocardial Infarction in Mice.

Cardiovasc Pharm Open Access 2016 9;5(5). Epub 2016 Sep 9.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130155PMC
September 2016

A series of robust genetic indicators for definitive identification of cardiomyocytes.

J Mol Cell Cardiol 2016 08 3;97:278-85. Epub 2016 Jun 3.

Department of Developmental and Regenerative Biology, The Black Family Stem Cell Institute, and The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2016.06.003DOI Listing
August 2016

Cardiac Stim1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC2/Akt Signaling.

Circulation 2016 Apr 2;133(15):1458-71; discussion 1471. Epub 2016 Mar 2.

From Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY (L.B., J.G.O., M.C., A.L., M.N., D.S.M., E.K., C.W.K., R.J.H., J.-S.H.); and Sorbonne Universités, UPMC Univ Paris 06, AP-HP, Institute of Cardiometabolism and Nutrition (ICAN), Pitié-Salpêtrière Hospital, Paris, France (C.P., J.-S.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829441PMC
April 2016