Roger J Daly

Roger J Daly

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Roger J Daly

Publications by authors named "Roger J Daly"

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The pseudokinases SgK269 and SgK223: A novel oncogenic alliance in human cancer.

Cell Adh Migr 2018 21;12(6):524-528. Epub 2017 Dec 21.

a Cancer Program, Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology , Monash University , Melbourne , Victoria , Australia.

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http://dx.doi.org/10.1080/19336918.2017.1394570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363038PMC
July 2019

Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target.

Neoplasia 2019 04 20;21(4):389-400. Epub 2019 Mar 20.

Cancer Program, Biomedicine Discovery Institute, Monash University, Victoria, Australia; Department of Biochemistry and Molecular Biology, Monash University, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2019.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426874PMC
April 2019

iLearn: an integrated platform and meta-learner for feature engineering, machine-learning analysis and modeling of DNA, RNA and protein sequence data.

Brief Bioinform 2019 Apr 24. Epub 2019 Apr 24.

Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1093/bib/bbz041DOI Listing
April 2019

Type IV Secretion System and Its Adhesin Subunit, CagL, Mediate Potent Inflammatory Responses in Primary Human Endothelial Cells.

Front Cell Infect Microbiol 2018 6;8:22. Epub 2018 Feb 6.

Infection & Immunity Program, Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.3389/fcimb.2018.00022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808116PMC
January 2019

Impact of the Anticancer Drug NT157 on Tyrosine Kinase Signaling Networks.

Mol Cancer Ther 2018 05 12;17(5):931-942. Epub 2018 Feb 12.

Cancer Program, Biomedicine Discovery Institute, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0377DOI Listing
May 2018

Effect of FAK inhibitor VS-6063 (defactinib) on docetaxel efficacy in prostate cancer.

Prostate 2018 03 5;78(4):308-317. Epub 2018 Jan 5.

Signalling Network Laboratory, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1002/pros.23476DOI Listing
March 2018

Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice.

Endocrinology 2018 03;159(3):1339-1351

Diabetes and Metabolism Division, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1210/en.2017-00851DOI Listing
March 2018

Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity.

Nucleic Acids Res 2017 Dec;45(21):12340-12353

Department of Biochemistry and Molecular Biology, Cancer Program, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1093/nar/gkx904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716096PMC
December 2017

Signalome-wide assessment of host cell response to hepatitis C virus.

Nat Commun 2017 05 8;8:15158. Epub 2017 May 8.

Infection &Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton Victoria 3800, Australia.

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http://dx.doi.org/10.1038/ncomms15158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424167PMC
May 2017

Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases.

J Biol Chem 2016 Oct 16;291(41):21571-21583. Epub 2016 Aug 16.

From the Cancer Program, Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Level 1, Building 77, Monash University, Clayton, Victoria 3800,

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http://dx.doi.org/10.1074/jbc.M116.748897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076828PMC
October 2016

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling.

Mol Cell Proteomics 2016 08 3;15(8):2671-85. Epub 2016 Jun 3.

¶Cancer Program, Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Level 1, Building 77, Monash University, VIC 3800, Australia;

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http://dx.doi.org/10.1074/mcp.M116.058313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974343PMC
August 2016

PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells.

J Cell Sci 2016 Apr 12;129(7):1340-54. Epub 2016 Feb 12.

The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia St. Vincent's Clinical School, Faculty of Medicine, UNSW, Darlinghurst 2010, New South Wales, Australia

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http://dx.doi.org/10.1242/jcs.179754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852720PMC
April 2016

The kinome 'at large' in cancer.

Nat Rev Cancer 2016 Feb;16(2):83-98

Cancer Program, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1038/nrc.2015.18DOI Listing
February 2016

Dataset from the global phosphoproteomic mapping of early mitotic exit in human cells.

Data Brief 2015 Dec 24;5:45-52. Epub 2015 Aug 24.

The Kinghorn Cancer Center, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia ; Department of Biochemistry and Molecular Biology, School of Biomedical Sciences Monash University, Clatyon, VIC 3800, Australia.

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http://dx.doi.org/10.1016/j.dib.2015.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564385PMC
December 2015

Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation Motifs.

Mol Cell Proteomics 2015 Aug 8;14(8):2194-212. Epub 2015 Jun 8.

¶St. Vincent's Clinical School, Faculty of Medicine, UNSW, Darlinghurst, NSW, Australia; From the ‡The Kinghorn Cancer Center, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia;

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http://www.mcponline.org/lookup/doi/10.1074/mcp.M114.046938
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http://dx.doi.org/10.1074/mcp.M114.046938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528247PMC
August 2015

The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling.

Mol Cancer 2015 Jul 29;14:139. Epub 2015 Jul 29.

Cancer Research Division, The Kinghorn Cancer Centre, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, NSW, 2010, Australia.

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http://dx.doi.org/10.1186/s12943-015-0412-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517651PMC
July 2015

FAK signaling in human cancer as a target for therapeutics.

Pharmacol Ther 2015 Feb 12;146:132-49. Epub 2014 Oct 12.

St. Vincent's Clinical School, Faculty of Medicine, University of New South Wales, St. Vincent's Hospital, Darlinghurst, NSW 2010, Australia; Department of Biochemistry and Molecular Biology, Faculty of Biomedical and Psychological Sciences, Monash University, Clayton, VIC 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2014.10.001DOI Listing
February 2015

The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking.

Sci Signal 2015 Feb 17;8(364):ra18. Epub 2015 Feb 17.

Centre for Cancer Biology, an Alliance between SA Pathology and University of South Australia, Adelaide, South Australia 5000, Australia. Discipline of Biochemistry, School of Molecular and Biomedical Science, The University of Adelaide, Adelaide, South Australia 5005, Australia. Department of Medicine, The University of Adelaide, Adelaide, South Australia 5005, Australia.

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http://dx.doi.org/10.1126/scisignal.2005547DOI Listing
February 2015

Grb10 deletion enhances muscle cell proliferation, differentiation and GLUT4 plasma membrane translocation.

J Cell Physiol 2014 Nov;229(11):1753-64

Diabetes and Obesity Research Program, The Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

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http://doi.wiley.com/10.1002/jcp.24628
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http://dx.doi.org/10.1002/jcp.24628DOI Listing
November 2014

Phosphoproteomic profiling identifies focal adhesion kinase as a mediator of docetaxel resistance in castrate-resistant prostate cancer.

Mol Cancer Ther 2014 Jan 5;13(1):190-201. Epub 2013 Nov 5.

Corresponding Author: Roger J. Daly, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Level 1, Building 77, Monash University, VIC 3800, Australia. Telephone: 61-3-990-29301;

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0225-TDOI Listing
January 2014

Professor Robert Sutherland FAA, AO (1947-2012).

Horm Mol Biol Clin Investig 2013 Dec;16(3):113-4

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http://dx.doi.org/10.1515/hmbci-2013-0046DOI Listing
December 2013

Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway.

Cancer Res 2013 Mar 1;73(6):1969-80. Epub 2013 Feb 1.

Cancer Research Program, The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1472DOI Listing
March 2013

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.

Authors:
Andrew V Biankin Nicola Waddell Karin S Kassahn Marie-Claude Gingras Lakshmi B Muthuswamy Amber L Johns David K Miller Peter J Wilson Ann-Marie Patch Jianmin Wu David K Chang Mark J Cowley Brooke B Gardiner Sarah Song Ivon Harliwong Senel Idrisoglu Craig Nourse Ehsan Nourbakhsh Suzanne Manning Shivangi Wani Milena Gongora Marina Pajic Christopher J Scarlett Anthony J Gill Andreia V Pinho Ilse Rooman Matthew Anderson Oliver Holmes Conrad Leonard Darrin Taylor Scott Wood Qinying Xu Katia Nones J Lynn Fink Angelika Christ Tim Bruxner Nicole Cloonan Gabriel Kolle Felicity Newell Mark Pinese R Scott Mead Jeremy L Humphris Warren Kaplan Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Angela Chou Venessa T Chin Lorraine A Chantrill Amanda Mawson Jaswinder S Samra James G Kench Jessica A Lovell Roger J Daly Neil D Merrett Christopher Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Nipun Kakkar Fengmei Zhao Yuan Qing Wu Min Wang Donna M Muzny William E Fisher F Charles Brunicardi Sally E Hodges Jeffrey G Reid Jennifer Drummond Kyle Chang Yi Han Lora R Lewis Huyen Dinh Christian J Buhay Timothy Beck Lee Timms Michelle Sam Kimberly Begley Andrew Brown Deepa Pai Ami Panchal Nicholas Buchner Richard De Borja Robert E Denroche Christina K Yung Stefano Serra Nicole Onetto Debabrata Mukhopadhyay Ming-Sound Tsao Patricia A Shaw Gloria M Petersen Steven Gallinger Ralph H Hruban Anirban Maitra Christine A Iacobuzio-Donahue Richard D Schulick Christopher L Wolfgang Richard A Morgan Rita T Lawlor Paola Capelli Vincenzo Corbo Maria Scardoni Giampaolo Tortora Margaret A Tempero Karen M Mann Nancy A Jenkins Pedro A Perez-Mancera David J Adams David A Largaespada Lodewyk F A Wessels Alistair G Rust Lincoln D Stein David A Tuveson Neal G Copeland Elizabeth A Musgrove Aldo Scarpa James R Eshleman Thomas J Hudson Robert L Sutherland David A Wheeler John V Pearson John D McPherson Richard A Gibbs Sean M Grimmond

Nature 2012 Nov 24;491(7424):399-405. Epub 2012 Oct 24.

The Kinghorn Cancer Centre, 370 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/nature11547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530898PMC
November 2012

Grb10 regulates the development of fiber number in skeletal muscle.

FASEB J 2012 Sep 23;26(9):3658-69. Epub 2012 May 23.

Diabetes and Obesity Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.1096/fj.11-199349DOI Listing
September 2012

The PDZ-binding motif of MCC is phosphorylated at position -1 and controls lamellipodia formation in colon epithelial cells.

Biochim Biophys Acta 2012 Jun 28;1823(6):1058-67. Epub 2012 Mar 28.

Cancer Research Program, Garvan Institute of Medical Research, Sydney, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S01674889120007
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http://dx.doi.org/10.1016/j.bbamcr.2012.03.011DOI Listing
June 2012

Targeting the human kinome for cancer therapy.

Authors:
Roger J Daly

Crit Rev Oncog 2012 ;17(1):vi-vii

St Vincent's Hospital Clinical School, Department of Medicine, University of New South Wales, Australia.

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http://dx.doi.org/10.1615/critrevoncog.v17.i1.10DOI Listing
May 2012

Targeting the human kinome for cancer therapy: current perspectives.

Crit Rev Oncog 2012 ;17(2):233-46

Garvan Institute of Medical Research, Australia.

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http://dx.doi.org/10.1615/critrevoncog.v17.i2.70DOI Listing
May 2012

Signalling through the grapevine.

EMBO Rep 2012 Mar 1;13(3):178-80. Epub 2012 Mar 1.

Goethe University Medical School, Frankfurt, Germany.

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http://dx.doi.org/10.1038/embor.2012.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323131PMC
March 2012

Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells.

Cancer Res 2010 Nov 21;70(22):9391-401. Epub 2010 Sep 21.

Cancer Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital Clinical School and Bioanalytical Mass Spectrometry Facility, University of New South Wales, Sydney, New South Wales, Australia.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-10-0911DOI Listing
November 2010

Docking proteins.

FEBS J 2010 Nov 30;277(21):4356-69. Epub 2010 Sep 30.

Centre for Biological Systems Analysis (ZBSA), Albert-Ludwigs-University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07865.xDOI Listing
November 2010

Growth factor receptor-bound protein 14: a new modulator of photoreceptor-specific cyclic-nucleotide-gated channel.

EMBO Rep 2010 Nov 1;11(11):861-7. Epub 2010 Oct 1.

Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.

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http://embor.embopress.org/cgi/doi/10.1038/embor.2010.142
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http://dx.doi.org/10.1038/embor.2010.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966952PMC
November 2010

DUSP26 negatively affects the proliferation of epithelial cells, an effect not mediated by dephosphorylation of MAPKs.

Biochim Biophys Acta 2010 Sep 27;1803(9):1003-12. Epub 2010 Mar 27.

Garvan Institute of Medical Research, Darlinghurst, NSW, 2010 Australia.

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http://dx.doi.org/10.1016/j.bbamcr.2010.03.014DOI Listing
September 2010

PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality.

Int J Cancer 2010 Mar;126(5):1121-31

Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.1002/ijc.24831DOI Listing
March 2010

Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasis.

Mol Endocrinol 2009 Sep 18;23(9):1406-14. Epub 2009 Jun 18.

Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1210/me.2008-0386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737556PMC
September 2009

Function, regulation and pathological roles of the Gab/DOS docking proteins.

Cell Commun Signal 2009 Sep 8;7:22. Epub 2009 Sep 8.

Centre for Biological Systems Analysis (ZBSA), Albert-Ludwigs-University of Freiburg, Germany.

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http://dx.doi.org/10.1186/1478-811X-7-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747914PMC
September 2009

Molecular determinants of Grb14-mediated inhibition of insulin signaling.

Mol Endocrinol 2009 Jul 9;23(7):1043-51. Epub 2009 Apr 9.

Institut Cochin, Université Paris Descartes, Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche (UMR) 8104, Paris, France.

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http://dx.doi.org/10.1210/me.2008-0360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419176PMC
July 2009

How to Grb2 a Gab.

Structure 2009 Jun;17(6):779-81

Spemann Graduate School of Biology and Medicine, Albert-Ludwigs-University, 79104 Freiburg, Germany.

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http://dx.doi.org/10.1016/j.str.2009.05.003DOI Listing
June 2009

Dual-specificity phosphatases: critical regulators with diverse cellular targets.

Biochem J 2009 Mar;418(3):475-89

Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst 2010, Sydney, NSW, Australia.

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http://dx.doi.org/10.1042/bj20082234DOI Listing
March 2009

KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling.

Biochim Biophys Acta 2008 Mar 9;1783(3):383-93. Epub 2008 Jan 9.

Development Group, Cancer Research Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.1016/j.bbamcr.2007.12.007DOI Listing
March 2008

Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin.

Mol Biol Cell 2008 Jan 24;19(1):17-29. Epub 2007 Oct 24.

Departament de Biologia Cellular, Facultat de Medicina, Universitat de Barcelona, Casanova 143, 08036-Barcelona, Spain.

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http://dx.doi.org/10.1091/mbc.e07-05-0411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174165PMC
January 2008

Cell cycle control in breast cancer cells.

J Cell Biochem 2006 Feb;97(2):261-74

Cancer Research Program, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW 2010, Australia.

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http://doi.wiley.com/10.1002/jcb.20690
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http://dx.doi.org/10.1002/jcb.20690DOI Listing
February 2006

Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein.

J Biol Chem 2006 Jan 27;281(1):626-37. Epub 2005 Oct 27.

Cancer Research Program, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1074/jbc.M509567200DOI Listing
January 2006

Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14.

Mol Cell 2005 Oct;20(2):325-33

Structural Biology Program, Skirball Institute of Biomolecular Medicine and Department of Pharmacology, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1016/j.molcel.2005.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526137PMC
October 2005

Adapter protein connections: the MRL and Grb7 protein families.

Growth Factors 2005 Sep;23(3):193-201

Garvan Institute of Medical Research, St Vincent's Hospital, Cancer Research Program, Sydney, NSW, Australia.

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http://dx.doi.org/10.1080/08977190500196267DOI Listing
September 2005

Hormonal regulation of the Grb14 signal modulator and its role in cell cycle progression of MCF-7 human breast cancer cells.

J Cell Physiol 2005 Apr;203(1):85-93

Cancer Research Program, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1002/jcp.20199DOI Listing
April 2005

Distinction at the leading edge of the cell.

Bioessays 2005 Apr;27(4):349-52

Cancer Research Program, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, Australia.

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http://dx.doi.org/10.1002/bies.20213DOI Listing
April 2005

Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor.

Cancer Res 2005 Apr;65(8):3273-80

Cancer Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-2118DOI Listing
April 2005

Cortactin signalling and dynamic actin networks.

Authors:
Roger J Daly

Biochem J 2004 Aug;382(Pt 1):13-25

Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Sydney, NSW 2010, Australia.

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http://biochemj.org/lookup/doi/10.1042/BJ20040737
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http://dx.doi.org/10.1042/BJ20040737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133910PMC
August 2004

Solution structure of the human Grb7-SH2 domain/erbB2 peptide complex and structural basis for Grb7 binding to ErbB2.

J Biomol NMR 2003 Nov;27(3):205-19

Department of Biochemistry, University of Vermont College of Medicine Burlington, VT 05405, U.S.A.

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http://dx.doi.org/10.1023/a:1025498409113DOI Listing
November 2003

p27(Kip1) induces quiescence and growth factor insensitivity in tamoxifen-treated breast cancer cells.

Cancer Res 2003 Aug;63(15):4322-6

Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia.

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August 2003

A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton.

J Biol Chem 2003 Jun 2;278(24):21805-13. Epub 2003 Apr 2.

Cancer Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1074/jbc.M211407200DOI Listing
June 2003

Grb7-based molecular therapeutics in cancer.

Expert Rev Mol Med 2003 May 10;5(14):1-11. Epub 2003 May 10.

Department of Surgery and the Vermont Cancer Center, University of Vermont School of Medicine, Given Medical Building, Burlington, VT 05405, USA.

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http://dx.doi.org/10.1017/S1462399403006227DOI Listing
May 2003

Cyclin D1, EMS1 and 11q13 amplification in breast cancer.

Breast Cancer Res Treat 2003 Apr;78(3):323-35

Cancer Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1023/a:1023033708204DOI Listing
April 2003

The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer.

Oncogene 2002 Aug;21(33):5175-81

Cancer Research Program, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.1038/sj.onc.1205522DOI Listing
August 2002

Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7.

J Biol Chem 2002 Apr 24;277(14):11918-26. Epub 2002 Jan 24.

Department of Surgery and the Vermont Cancer Center, University of Vermont School of Medicine, Burlington, Vermont 05405, USA.

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http://www.jbc.org/content/early/2002/01/24/jbc.M111816200.f
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http://www.jbc.org/lookup/doi/10.1074/jbc.M111816200
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http://dx.doi.org/10.1074/jbc.M111816200DOI Listing
April 2002

PKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2.

EMBO J 2002 Jan;21(1-2):72-82

Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125816PMC
http://dx.doi.org/10.1093/emboj/21.1.72DOI Listing
January 2002