Roger H Reeves

Roger H Reeves

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Roger H Reeves

Roger H Reeves

Publications by authors named "Roger H Reeves"

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Hydroxyurea Improves Spatial Memory and Cognitive Plasticity in Mice and Has a Mild Effect on These Parameters in a Down Syndrome Mouse Model.

Front Aging Neurosci 2019 14;11:96. Epub 2019 May 14.

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.

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http://dx.doi.org/10.3389/fnagi.2019.00096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527804PMC
May 2019

Hydroxyurea attenuates oxidative, metabolic, and excitotoxic stress in rat hippocampal neurons and improves spatial memory in a mouse model of Alzheimer's disease.

Neurobiol Aging 2018 12 29;72:121-133. Epub 2018 Aug 29.

Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215724PMC
December 2018

Associations Between Medical History, Cognition, and Behavior in Youth With Down Syndrome: A Report From the Down Syndrome Cognition Project.

Am J Intellect Dev Disabil 2018 11;123(6):514-528

Tracie C. Rosser, Emory University; Jamie O. Edgin, University of Arizona; George T. Capone, Kennedy Krieger Institute; Debra R. Hamilton, Emory University; Emily G. Allen, Emory University; Kenneth J. Dooley, Emory University; Payal Anand, University of Arizona; John F. Strang, Children's National Medical Center; A. Chelsea Armour, Children's National Medical Center; Michelle A. Frank-Crawford, Kennedy Krieger Institute; Marie Moore Channell, MIND Institute; Elizabeth I. Pierpont, University of Wisconsin; Eleanor Feingold, University of Pittsburgh; Cheryl L. Maslen, Oregon Health & Science University; Roger H. Reeves, Johns Hopkins University; and Stephanie L. Sherman, Emory University.

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http://dx.doi.org/10.1352/1944-7558-123.6.514DOI Listing
November 2018

The Influence of trisomy 21 on facial form and variability.

Am J Med Genet A 2017 Nov 21;173(11):2861-2872. Epub 2017 Sep 21.

Department of Anthropology, The Pennsylvania State University, University Park, Pennsylvania.

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http://dx.doi.org/10.1002/ajmg.a.38464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679727PMC
November 2017

Increased Sparsity of Hippocampal CA1 Neuronal Ensembles in a Mouse Model of Down Syndrome Assayed by Arc Expression.

Front Neural Circuits 2017 3;11. Epub 2017 Feb 3.

Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of MedicineBaltimore, MD, USA; Department of Neurology, Johns Hopkins University School of MedicineBaltimore, MD, USA.

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http://dx.doi.org/10.3389/fncir.2017.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289947PMC
October 2017

The Arizona Cognitive Test Battery for Down Syndrome: Test-Retest Reliability and Practice Effects.

Am J Intellect Dev Disabil 2017 05;122(3):215-234

Jamie O. Edgin and Payal Anand, University of Arizona; Tracie Rosser, Emory University; Elizabeth I. Pierpont, University of Wisconsin-Madison and University of Minnesota; Carlos Figueroa, University of Arizona; Debra Hamilton and Lillie Huddleston, Georgia State University; Gina Mason, Cornell University; Goffredina Spanò, University of Arizona; Lisa Toole, Johns Hopkins University; Mina Nguyen-Driver, Oregon Health Sciences University; George Capone, Johns Hopkins University; Leonard Abbeduto, University of Wisconsin-Madison and University of California, Davis; Cheryl Maslen, Oregon Health Sciences University; Roger H. Reeves, Johns Hopkins University; and Stephanie Sherman, Emory University.

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http://dx.doi.org/10.1352/1944-7558-122.3.215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215707PMC
May 2017

DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome.

Proc Natl Acad Sci U S A 2017 02 30;114(7):E1224-E1233. Epub 2017 Jan 30.

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1614893114
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http://dx.doi.org/10.1073/pnas.1614893114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321030PMC
February 2017

Increased Skin Tumor Incidence and Keratinocyte Hyper-Proliferation in a Mouse Model of Down Syndrome.

PLoS One 2016 11;11(1):e0146570. Epub 2016 Jan 11.

Department of Physiology and McKusick Nathans Institute for Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0146570PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708994PMC
July 2016

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.

Hum Mol Genet 2016 07 23;25(14):3011-3028. Epub 2016 Jun 23.

Departments of Pediatrics, Pathology, and Human Genetics, The University of Chicago, Chicago, IL 60637, USA,

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http://dx.doi.org/10.1093/hmg/ddw155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181596PMC
July 2016

Editorial: Intellectual Disabilities in Down Syndrome from Birth and Throughout Life: Assessment and Treatment.

Front Behav Neurosci 2016 14;10:120. Epub 2016 Jun 14.

Department of Physiology and McKusick Nathans Institute for Genetic Medicine, Johns Hopkins University School of Medicine Baltimore, MD, USA.

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http://dx.doi.org/10.3389/fnbeh.2016.00120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906652PMC
July 2016

Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier.

Genetics 2016 06 30;203(2):763-70. Epub 2016 Mar 30.

Department of Physiology and Institute for Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205

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http://dx.doi.org/10.1534/genetics.116.188045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896192PMC
June 2016

Chronic up-regulation of sonic hedgehog has little effect on postnatal craniofacial morphology of euploid and trisomic mice.

Dev Dyn 2016 Feb 6;245(2):114-22. Epub 2015 Dec 6.

Department of Anthropology, Pennsylvania State University, University Park, Pennsylvania.

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http://dx.doi.org/10.1002/dvdy.24361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715749PMC
February 2016

Assessing cognitive improvement in people with Down syndrome: important considerations for drug-efficacy trials.

Handb Exp Pharmacol 2015 ;228:335-80

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA,

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http://dx.doi.org/10.1007/978-3-319-16522-6_12DOI Listing
September 2015

The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model.

BMC Dev Biol 2015 Jul 25;15:30. Epub 2015 Jul 25.

Department of Physiology at Johns Hopkins, Biophysics 201, 725 N. Wolfe St., Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1186/s12861-015-0080-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514943PMC
July 2015

Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology.

Dis Model Mech 2015 Mar 24;8(3):271-9. Epub 2014 Dec 24.

Department of Anthropology, Pennsylvania State University, University Park, PA 16802, USA

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http://dx.doi.org/10.1242/dmm.017889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348564PMC
March 2015

Chronic up-regulation of the SHH pathway normalizes some developmental effects of trisomy in Ts65Dn mice.

Mech Dev 2015 Feb 12;135:68-80. Epub 2014 Dec 12.

Department of Physiology and Institute for Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mod.2014.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297701PMC
February 2015

Overlapping trisomies for human chromosome 21 orthologs produce similar effects on skull and brain morphology of Dp(16)1Yey and Ts65Dn mice.

Am J Med Genet A 2014 Aug 1;164A(8):1981-1990. Epub 2014 May 1.

Department of Anthropology, Pennsylvania State University, University Park, Pennsylvania.

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http://dx.doi.org/10.1002/ajmg.a.36594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107150PMC
August 2014

Allelic Interaction between and in the Pathogenesis of Cardiac Atrioventricular Septal Defects.

AIMS Genet 2014 ;1(1):1-19

Department of Physiology and the Institute for Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://www.aimspress.com/article/10.3934/genet.2014.1.1
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http://dx.doi.org/10.3934/genet.2014.1.1#sthash.jksuJTeC.dpufDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200510PMC
January 2014

Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model.

Sci Transl Med 2013 Sep;5(201):201ra120

Department of Physiology and Institute for Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1126/scitranslmed.3005983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006719PMC
September 2013

Size does not always matter: Ts65Dn Down syndrome mice show cerebellum-dependent motor learning deficits that cannot be rescued by postnatal SAG treatment.

J Neurosci 2013 Sep;33(39):15408-13

Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, 1105 BA Amsterdam, The Netherlands, Department of Physiology and Institute for Medical Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21025, and Department of Neuroscience, Erasmus MC Rotterdam, NL-3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1523/JNEUROSCI.2198-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858639PMC
September 2013

Trisomy 21 and facial developmental instability.

Am J Phys Anthropol 2013 May 15;151(1):49-57. Epub 2013 Mar 15.

Department of Anthropology, The Pennsylvania State University, University Park, PA 16802, USA.

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http://dx.doi.org/10.1002/ajpa.22255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744194PMC
May 2013

A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome.

Prog Brain Res 2012 ;197:223-36

Department of Physiology, The McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MA, USA.

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http://dx.doi.org/10.1016/B978-0-444-54299-1.00011-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405118PMC
September 2012

Trisomy 21 and early brain development.

Trends Neurosci 2012 Feb 9;35(2):81-91. Epub 2011 Dec 9.

Department of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA 02118, USA.

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http://dx.doi.org/10.1016/j.tins.2011.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273608PMC
February 2012

Morphological integration of soft-tissue facial morphology in Down Syndrome and siblings.

Am J Phys Anthropol 2011 Dec 14;146(4):560-8. Epub 2011 Oct 14.

The Pennsylvania State University-Anthropology, University Park, PA 16802, USA.

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http://dx.doi.org/10.1002/ajpa.21583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258662PMC
December 2011

The use of mouse models to understand and improve cognitive deficits in Down syndrome.

Dis Model Mech 2011 Sep 4;4(5):596-606. Epub 2011 Aug 4.

Department of Physiology and McKusick-Nathans, Institute for Medical Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1242/dmm.007716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180223PMC
September 2011

Increased survival following tumorigenesis in Ts65Dn mice that model Down syndrome.

Cancer Res 2011 May 5;71(10):3573-81. Epub 2011 Apr 5.

Department of Physiology and McKusick Nathans Institute for Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-4489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096739PMC
May 2011

Increased male reproductive success in Ts65Dn "Down syndrome" mice.

Mamm Genome 2010 Dec 26;21(11-12):543-9. Epub 2010 Nov 26.

Department of Biology, Franklin and Marshall College, P.O. Box 3003, Lancaster, PA 17604, USA.

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http://dx.doi.org/10.1007/s00335-010-9300-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002156PMC
December 2010

Down syndrome: from understanding the neurobiology to therapy.

J Neurosci 2010 Nov;30(45):14943-5

Department of Pediatrics, Intellectual and Developmental Disabilities Research Center, University of Colorado Denver, Aurora, Colorado 80045, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3728-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842485PMC
November 2010

Development and validation of the Arizona Cognitive Test Battery for Down syndrome.

J Neurodev Disord 2010 Sep;2(3):149-164

Department of Psychology, University of Arizona, 1503 E. University Blvd., Tucson, AZ 85721, USA.

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http://dx.doi.org/10.1007/s11689-010-9054-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026140PMC
September 2010

Complex contributions of Ets2 to craniofacial and thymus phenotypes of trisomic "Down syndrome" mice.

Am J Med Genet A 2009 Oct;149A(10):2158-65

Department of Anthropology, Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://dx.doi.org/10.1002/ajmg.a.33012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903219PMC
October 2009

The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome.

J Neurosci 2009 May;29(18):5938-48

Department of Neurology and Neurological Sciences and the Center for Research and Treatment of Down Syndrome, Stanford University Medical Center, Stanford, California 94305-5489, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1547-09.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849469PMC
May 2009

A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog.

Mech Dev 2009 Mar-Apr;126(3-4):212-9. Epub 2008 Nov 21.

Department of Physiology and McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University School of Medicine, Biophysics 201, 725 North Wolfe Street, Baltimore, MD 21205, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S092547730800176
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http://dx.doi.org/10.1016/j.mod.2008.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820727PMC
April 2009

A year of unprecedented progress in Down syndrome basic research.

Ment Retard Dev Disabil Res Rev 2007 ;13(3):215-20

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1002/mrdd.20165DOI Listing
April 2008

Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome.

Nature 2008 Jan;451(7174):73-5

Department of Physiology and The Institute for Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1038/nature06446DOI Listing
January 2008

Differential effects of trisomy on brain shape and volume in related aneuploid mouse models.

Am J Med Genet A 2007 May;143A(10):1060-70

Department of Anthropology, The Pennsylvania State University, University Park, Pennsylvania 16801, USA.

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http://dx.doi.org/10.1002/ajmg.a.31721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246902PMC
May 2007

Effects of aneuploidy on skull growth in a mouse model of Down syndrome.

J Anat 2007 Apr;210(4):394-405

Department of Anthropology, The Pennsylvania State University, PA 16801, USA.

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http://dx.doi.org/10.1111/j.1469-7580.2007.00705.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2100298PMC
April 2007

Microstructure of trabecular bone in a mouse model for Down syndrome.

Anat Rec (Hoboken) 2007 Apr;290(4):414-21

Department of Anthropology, Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://dx.doi.org/10.1002/ar.20494DOI Listing
April 2007

Hippocampal hypocellularity in the Ts65Dn mouse originates early in development.

Brain Res 2006 Aug 7;1104(1):153-9. Epub 2006 Jul 7.

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205-2185, USA.

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http://dx.doi.org/10.1016/j.brainres.2006.05.022DOI Listing
August 2006

Down syndrome mouse models are looking up.

Authors:
Roger H Reeves

Trends Mol Med 2006 Jun 4;12(6):237-40. Epub 2006 May 4.

Johns Hopkins University School of Medicine, Department of Physiology and McKusick-Nathans Institute for Genetic Medicine, Biophysics 201, 725 North Wolfe Street, Baltimore, MD 21025, USA.

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http://dx.doi.org/10.1016/j.molmed.2006.04.005DOI Listing
June 2006

A quantitative trait loci analysis to map genes involved in lipopolysaccharide-induced inflammatory response: identification of macrophage scavenger receptor 1 as a candidate gene.

J Immunol 2006 Mar;176(6):3767-73

Division of Pediatric Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.4049/jimmunol.176.6.3767DOI Listing
March 2006

Understanding the basis for Down syndrome phenotypes.

PLoS Genet 2006 Mar;2(3):e50

Department of Physiology at Johns Hopkins University School of Medicine, and at McKusick-Nathans Institute for Genetic Medicine, Baltimore, Maryland, United States of America.

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https://dx.plos.org/10.1371/journal.pgen.0020050
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http://dx.doi.org/10.1371/journal.pgen.0020050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420680PMC
March 2006

Perinatal loss of Ts65Dn Down syndrome mice.

Genetics 2006 Jan 19;172(1):437-43. Epub 2005 Sep 19.

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1534/genetics.105.050898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456171PMC
January 2006

Defective cerebellar response to mitogenic Hedgehog signaling in Down [corrected] syndrome mice.

Proc Natl Acad Sci U S A 2006 Jan 23;103(5):1452-6. Epub 2006 Jan 23.

Department of Physiology and McKusick-Nathans Institute for Genetic Medicine, Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0510750103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360600PMC
January 2006

IL-10 plasma levels are elevated after LPS injection in splenectomized A/J mice.

J Surg Res 2005 Nov 8;129(1):101-6. Epub 2005 Aug 8.

Division of Pediatric Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1016/j.jss.2005.06.008DOI Listing
November 2005

Protection from lethal endotoxic shock after testosterone depletion is linked to chromosome X.

Shock 2005 Oct;24(4):318-23

Division of Pediatric Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1097/01.shk.0000177639.22863.99DOI Listing
October 2005

Tumor suppressor in lung cancer 1 (TSLC1) alters tumorigenic growth properties and gene expression.

Mol Cancer 2005 Aug 5;4:28. Epub 2005 Aug 5.

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205-2185, USA.

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http://dx.doi.org/10.1186/1476-4598-4-28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208945PMC
August 2005

Long-range chromosomal engineering is more efficient in vitro than in vivo.

Transgenic Res 2005 Jun;14(3):325-32

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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June 2005

Genetic determinants influencing the response to injury, inflammation, and sepsis.

Shock 2005 Jan;23(1):11-7

Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1097/01.shk.0000144134.03598.c5DOI Listing
January 2005

The Collaborative Cross, a community resource for the genetic analysis of complex traits.

Authors:
Gary A Churchill David C Airey Hooman Allayee Joe M Angel Alan D Attie Jackson Beatty William D Beavis John K Belknap Beth Bennett Wade Berrettini Andre Bleich Molly Bogue Karl W Broman Kari J Buck Ed Buckler Margit Burmeister Elissa J Chesler James M Cheverud Steven Clapcote Melloni N Cook Roger D Cox John C Crabbe Wim E Crusio Ariel Darvasi Christian F Deschepper R W Doerge Charles R Farber Jiri Forejt Daniel Gaile Steven J Garlow Hartmut Geiger Howard Gershenfeld Terry Gordon Jing Gu Weikuan Gu Gerald de Haan Nancy L Hayes Craig Heller Heinz Himmelbauer Robert Hitzemann Kent Hunter Hui-Chen Hsu Fuad A Iraqi Boris Ivandic Howard J Jacob Ritsert C Jansen Karl J Jepsen Dabney K Johnson Thomas E Johnson Gerd Kempermann Christina Kendziorski Malak Kotb R Frank Kooy Bastien Llamas Frank Lammert Jean-Michel Lassalle Pedro R Lowenstein Lu Lu Aldons Lusis Kenneth F Manly Ralph Marcucio Doug Matthews Juan F Medrano Darla R Miller Guy Mittleman Beverly A Mock Jeffrey S Mogil Xavier Montagutelli Grant Morahan David G Morris Richard Mott Joseph H Nadeau Hiroki Nagase Richard S Nowakowski Bruce F O'Hara Alexander V Osadchuk Grier P Page Beverly Paigen Kenneth Paigen Abraham A Palmer Huei-Ju Pan Leena Peltonen-Palotie Jeremy Peirce Daniel Pomp Michal Pravenec Daniel R Prows Zhonghua Qi Roger H Reeves John Roder Glenn D Rosen Eric E Schadt Leonard C Schalkwyk Ze'ev Seltzer Kazuhiro Shimomura Siming Shou Mikko J Sillanpää Linda D Siracusa Hans-Willem Snoeck Jimmy L Spearow Karen Svenson Lisa M Tarantino David Threadgill Linda A Toth William Valdar Fernando Pardo-Manuel de Villena Craig Warden Steve Whatley Robert W Williams Tim Wiltshire Nengjun Yi Dabao Zhang Min Zhang Fei Zou

Nat Genet 2004 Nov;36(11):1133-7

The Jackson Laboratory, 600 Main Street Bar Harbor, Maine 04609, USA.

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http://dx.doi.org/10.1038/ng1104-1133DOI Listing
November 2004

Protection from doxorubicin-induced cardiac toxicity in mice with a null allele of carbonyl reductase 1.

Cancer Res 2003 Oct;63(20):6602-6

Johns Hopkins University School of Medicine, Department of Physiology, Baltimore, Maryland 21205, USA

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October 2003

Global disruption of the cerebellar transcriptome in a Down syndrome mouse model.

Hum Mol Genet 2003 Aug;12(16):2013-9

Department of Physiology, Johns Hopkins School of Medicine, Baltimore, MD 21210, USA.

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http://dx.doi.org/10.1093/hmg/ddg217DOI Listing
August 2003

Functional genomics: a time and place for every gene.

Authors:
Roger H Reeves

Nature 2002 Dec;420(6915):518-9

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http://dx.doi.org/10.1038/420518aDOI Listing
December 2002

Genetic and comparative mapping of genes dysregulated in mouse hearts lacking the Hand2 transcription factor gene.

Genomics 2002 Dec;80(6):593-600

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1006/geno.2002.7009DOI Listing
December 2002

The effects of piracetam on cognitive performance in a mouse model of Down's syndrome.

Physiol Behav 2002 Nov;77(2-3):403-9

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Ross 618, 720 Rutland Avenue, Baltimore, MD 21205-2196, USA.

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http://dx.doi.org/10.1016/s0031-9384(02)00873-9DOI Listing
November 2002

Genetic contribution to the septic response in a mouse model.

Shock 2002 Oct;18(4):342-7

Division of Pediatric Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1097/00024382-200210000-00009DOI Listing
October 2002

Comparative genomic sequence analysis of the human chromosome 21 Down syndrome critical region.

Genome Res 2002 Sep;12(9):1323-32

Human Genome Research Group, Genomic Sciences Center, RIKEN Yokohama Institute, 1-7-22, Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, Japan.

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http://dx.doi.org/10.1101/gr.153702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC186650PMC
September 2002

Meeting Report: 15th International Mouse Genome Conference.

Mamm Genome 2002 May;13(5):229-33

National Human Genome Research Institute, National Institutes of Health, Bldg. 49, Rm. 4B67, 49 Convent Dr., Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s00335-002-4001-6DOI Listing
May 2002

Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome.

Am J Med Genet 2002 Feb;107(4):317-24

Department of Anthropology, Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://dx.doi.org/10.1002/ajmg.10175DOI Listing
February 2002