Roderick H J Houwen

J Lipid Res 2019 Oct 17;60(10):1787-1800. Epub 2019 Jul 17.

Division of Pediatrics, Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands

J Pediatr Gastroenterol Nutr 2019 Sep;69(3):310-316

Department of Paediatric Gastroenterology, Hepatology and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Liver Int 2019 Sep 26;39(9):1768-1775. Epub 2019 Jun 26.

Department of Pediatric Gastroenterology, Erasmus University Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands.

Liver Int 2019 Jun 17. Epub 2019 Jun 17.

University Medical Library, University of Basel, Basel, Switzerland.

J Cyst Fibros 2019 Mar 29;18(2):286-293. Epub 2018 Sep 29.

Pediatric Gastroenterology and Hepatology, Department of Pediatrics, University of Groningen, Beatrix Children's Hospital - University Medical Center Groningen, PO Box 30001, 9700 RB Groningen, the Netherlands. Electronic address:

JAMA Neurol 2019 Mar;76(3):342-350

Institute of Human Genetics, University Medical Center Leipzig, Leipzig, Germany.

Genet Med 2019 02 6;21(2):319-330. Epub 2018 Jun 6.

Department of Metabolic Diseases, Wilhelmina Children's Hospital, University Medical Center Utrecht, Lundlaan 6, Utrecht, 3584 EA, The Netherlands.

Clin Res Hepatol Gastroenterol 2019 02 17;43(1):20-36. Epub 2018 Sep 17.

Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center, Utrecht, Netherlands. Electronic address:

Cell Rep 2019 Feb;26(7):1701-1708.e3

Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht University, 3584 EA Utrecht, the Netherlands. Electronic address:

Hum Mol Genet 2019 01;28(1):96-104

Department of Pediatrics, University Medical Center Utrecht, Utrecht University, Utrecht CX, The Netherlands.

Br J Nutr 2019 Jan 16;121(2):195-201. Epub 2018 Nov 16.

1Department of Paediatric Gastroenterology,University Medical Centre Utrecht,KE.04.133.1,P.O. Box 85500,3508 GA Utrecht,The Netherlands.

Eur Respir J 2018 09 17;52(3). Epub 2018 Sep 17.

Dept of Pediatric Pulmonology, Wilhelmina Children's Hospital - University Medical Center, Utrecht University, Utrecht, The Netherlands.

Gastroenterology 2018 07 29;155(1):130-143.e15. Epub 2018 Mar 29.

Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria; St. Anna Kinderspital and Children's Cancer Research Institute, Department of Pediatrics, Medical University of Vienna, Vienna, Austria. Electronic address:

APMIS 2018 Mar 31;126(3):186-190. Epub 2018 Jan 31.

Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.

Curr Opin Pulm Med 2017 11;23(6):551-555

aDepartment of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands bPediatric Gastroenterology, Hadassah University Hospital, Jerusalem, Israel.

J Pediatr Gastroenterol Nutr 2017 10;65(4):425-429

*Department of Paediatric Gastroenterology, University Medical Centre-Wilhelmina Children's Hospital, Utrecht†Department of Paediatric Gastroenterology, University Medical Centre Groningen, University of Groningen, Groningen‡Department of Paediatric Gastroenterology, Maxima Medical Centre, Veldhoven§Department of Paediatric Gastroenterology, Radboud University Medical Centre-Amalia Children's Hospital, Nijmegen||Department of Paediatric Gastroenterology, Emma Children's Hospital, Academic Medical Center, Amsterdam¶Department of Paediatric Gastroenterology, Erasmus Medical Centre-Sophia Children's Hospital, Rotterdam, The Netherlands.

Surg Endosc 2017 08 18;31(8):3122-3129. Epub 2016 Nov 18.

Department of Pediatric Surgery, Wilhelmina Children's Hospital, University Medical Center Utrecht, Room: KE.04.140.5, PO Box 85090, 3508 AB, Utrecht, The Netherlands.

Surg Endosc 2017 07 1;31(7):2910-2917. Epub 2016 Nov 1.

Department of Pediatric Surgery, Wilhelmina Children's Hospital, University Medical Center Utrecht, Room: KE.04.140.5, PO Box 85090, 3508 AB, Utrecht, The Netherlands.

N Engl J Med 2017 07 28;377(1):52-61. Epub 2017 Jun 28.

From the Section of Molecular Development of the Immune System, Laboratory of Immunology (A.O., W.A.C., A.R.M., H.F.M., M.J.L.), the Clinical Genomics Program (A.O., W.A.C., A.R.M., Y.Z., H.F.M., H.C.S., M.J.L.), and the Human Immunological Diseases Section, Laboratory of Host Defenses (Y.Z., H.C.S.), National Institute of Allergy and Infectious Diseases, the Laboratory of Pathology, National Cancer Institute (S.P.), and Radiology and Imaging Sciences, Clinical Center (L.R.F.), National Institutes of Health, Bethesda, MD; the Department of Pediatrics, Division of Allergy and Immunology (A.O., E.K.-A., S.B., A. Kiykim, I.O.), and the Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition (E.T., D.E.), Marmara University, Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases (A.O., E.K.-A., S.B., A. Kiykim, I.O.), and the Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, İstanbul University Cerrahpaşa Faculty of Medicine (Ö.F.B., T.E.), Istanbul, and the Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Gazi University (B.D., S.S.), the Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Faculty of Medicine, Başkent University (F.O., Z.B., M.G.), and the Pediatric Gastroenterology Clinic, Dr. Sami Ulus Children's Hospital (A.U.A.), Ankara - all in Turkey; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases and the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (R.C.A., C.D.C., N.K.S., A. Krolo, K.B.), Clinical Institute of Pathology (R.K.), the Department of Pediatrics and Adolescent Medicine (K.B.), and St. Anna Kinderspital and Children's Cancer Research Institute, Department of Pediatrics (K.B.), Medical University of Vienna, Vienna; Merck Research Laboratories (J.J.M.), and the Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Harvard Medical School (S.B.S.), Boston; and the Department of Pediatric Gastroenterology, University Medical Center-Wilhelmina Children's Hospital (R.H.J.H.), and the Department of Rheumatology and Clinical Immunology, University Medical Center (H.L.L.), Utrecht, the Netherlands.

J Cyst Fibros 2017 May 7;16(3):410-417. Epub 2017 Mar 7.

Department of Paediatric Gastroenterology, and Cystic Fibrosis Centre, University Medical Centre Utrecht, KE.04.133.1, P.O. Box 85500, 3508 GA Utrecht, The Netherlands.

J Biol Chem 2017 05 16;292(19):7904-7920. Epub 2017 Mar 16.

From the Division of Pediatrics, Wilhelmina Children's Hospital,

Nutr Clin Pract 2017 Feb 10;32(1):130-132. Epub 2016 Jul 10.

4 Department of Pediatric Gastroenterology, and Cystic Fibrosis Center Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands.

J Cyst Fibros 2016 11;15(6):834-838

Department of Pediatric Gastroenterology, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

Clin Nutr 2016 06 23;35(3):654-9. Epub 2015 Apr 23.

Department of Paediatric Gastroenterology, and Cystic Fibrosis Centre, University Medical Centre Utrecht, KE.04.133.1, P.O. Box 85500, 3508 GA Utrecht, The Netherlands.

J Hepatol 2016 06 12;64(6):1339-47. Epub 2016 Feb 12.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands; Department of Gastroenterology & Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

Sci Transl Med 2016 06;8(344):344ra84

Department of Pediatric Pulmonology, Wilhelmina Children's Hospital, University Medical Center Utrecht, 3584 EA Utrecht, Netherlands. Laboratory of Translational Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, 3584 EA Utrecht, Netherlands. Regenerative Medicine Center Utrecht, University Medical Center Utrecht, 3584 CX Utrecht, Netherlands.

Dis Model Mech 2016 Jan;9(1):25-38

Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 104, 3584 CM Utrecht, The Netherlands.

J Pediatr Gastroenterol Nutr 2015 Sep;61(3):355-60

*Internal Medicine and Dermatology, Dietetics †Department of Paediatric Pulmonology ‡Department of Paediatric Gastroenterology, Cystic Fibrosis Centre Utrecht, University Medical Centre Utrecht, Utrecht, the Netherlands.

J Pediatr Gastroenterol Nutr 2015 Jul;61(1):113-8

*Department of Pediatric Gastroenterology and Hepatology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen †Department of Pediatric Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands.

World J Gastroenterol 2015 Jun;21(24):7553-7

Amani Mubarak, Victorien M Wolters, Roderick HJ Houwen, Department of Pediatric Gastroenterology, University Medical Center Utrecht, Wilhelmina Children's Hospital, 3508 AB Utrecht, The Netherlands.

Hepatology 2015 Apr 23;61(4):1382-91. Epub 2015 Feb 23.

Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands; Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.

Br J Nutr 2015 Apr 12;113(7):1096-101. Epub 2015 Mar 12.

Department of Paediatric Gastroenterology and Cystic Fibrosis Centre,University Medical Centre Utrecht,Internal Address KE.04.133.1, PO Box 85500,3508GAUtrecht,The Netherlands.

J Gastroenterol Hepatol 2015 Mar;30(3):535-9

Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, The Netherlands.

Gut 2015 Jan 26;64(1):6-8. Epub 2014 May 26.

Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.

N Engl J Med 2014 Nov;371(20):1900-7

From the Division of Pediatrics, Department of Metabolic Diseases (P.M.H., G.V.), and the Division of Pediatrics, Department of Pediatric Gastroenterology (R.H.J.H.), Wilhelmina Children's Hospital, and the Center for Molecular Medicine, Department of Medical Genetics (G.R.M., M.J.G., K.D., M.H., B.Z., J.J.S., N.M.V.-D., G.H.), University Medical Center Utrecht, Utrecht, Laboratory Genetic Metabolic Diseases, Departments of Clinical Chemistry and Pediatrics, Academic Medical Center, Amsterdam (S.F., J.P.N.R., M.T., R.J.A.W.), the Division of Pediatrics, Department of Metabolic Diseases, and Laboratory Genetic Metabolic Diseases, Maastricht University Medical Center, Maastricht (M.E.R.-G.), and the Department of Pediatrics, Nijmegen Center for Mitochondrial Disorders, Radboud University Medical Center, Nijmegen (M.C.V.) - all in the Netherlands; the National Centre for Inherited Metabolic Disorders, Children's University Hospital, Dublin, Ireland (A.A.M.); the Department of Pediatric Metabolism and Nutrition, Gazi University School of Medicine, Ankara, Turkey (I.O.); and the Department of Paediatric Metabolic Medicine, Sheffield Children's Hospital, Sheffield (M.J.S.), the Department of Metabolic Medicine, Great Ormond Street Hospital NHS Foundation Trust, London (M.C.), Chemical Pathology, Department of Laboratory Medicine, Salisbury (N.O.), and the Department of Clinical Biochemistry, Southampton General Hospital, Southampton (V.W.) - all in the United Kingdom.

PLoS One 2013 19;8(11):e80553. Epub 2013 Nov 19.

Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands ; Department of Metabolic Diseases, University Medical Center Utrecht, Utrecht, The Netherlands.

Gastroenterology 2014 Jul 12;147(1):65-68.e10. Epub 2014 Apr 12.

Division of Pediatrics, Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

Ann Surg 2014 Feb;259(2):388-93

*Department of Pediatric Surgery, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands †Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands; and ‡Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.

Acta Paediatr 2014 Feb 18;103(2):162-7. Epub 2013 Nov 18.

Internal Medicine and Dermatology, Dietetics and, Cystic Fibrosis Centre Utrecht, University Medical Centre Utrecht, Utrecht, The Netherlands.

World J Gastroenterol 2013 Nov;19(41):7114-20

Amani Mubarak, Victorien M Wolters, Roderick HJ Houwen, Department of Pediatric Gastroenterology, University Medical Center Utrecht, Wilhelmina Children's Hospital, 3508 AB Utrecht, The Netherlands.

Clin Gastroenterol Hepatol 2013 Aug 28;11(8):1028-35.e1-2. Epub 2013 Mar 28.

Department of Gastroenterology, University Hospital Heidelberg, Heidelberg, Germany.

J Pediatr (Rio J) 2012 Mar-Apr;88(2):173-6. Epub 2012 Mar 20.

Catharina Hospital, Eindhoven, the Netherlands.

World J Gastroenterol 2012 Aug;18(32):4399-403

Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands.

Metallomics 2012 Jul 4;4(7):606-13. Epub 2012 May 4.

Department of Metabolic Diseases, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands.

Clin Gastroenterol Hepatol 2011 Dec 4;9(12):1086-91. Epub 2011 Aug 4.

Department of Pediatric Gastroenterology and Hepatology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

J Gastrointest Surg 2011 Oct 29;15(10):1872-8. Epub 2011 Jul 29.

Department of Pediatric Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

Dig Liver Dis 2011 Sep 17;43(9):682-7. Epub 2011 Mar 17.

Department of Pediatric Surgery, Wilhelmina Children's Hospital Utrecht, The Netherlands.

Pediatrics 2011 Sep 22;128(3):547-52. Epub 2011 Aug 22.

Department of Pediatric Gastroenterology, Leiden University Medical Centre, Leiden, Netherlands.

Curr Gastroenterol Rep 2011 Jun;13(3):265-70

Department of Pediatric Gastroenterology [KE.04.133.1], University Medical Center Utrecht, Postbox 85090, 3508 AB Utrecht, The Netherlands.

J Pediatr Gastroenterol Nutr 2011 May;52(5):554-7

Department of Pediatric Gastroenterology, University Medical Center Utrecht, The Netherlands.

Nat Med 2011 Apr;17(4):413; author reply 413-4

Ned Tijdschr Geneeskd 2010 ;154:A1904

Leids Universitair Medisch Centrum, afd. Kindergeneeskunde, Leiden, the Netherlands.

J Pediatr Gastroenterol Nutr 2010 Nov;51(5):603-9

Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands.

Best Pract Res Clin Gastroenterol 2010 Oct;24(5):541-53

Department of Paediatric Gastroenterology (KE.01.144.3), Wilhelmina Children's Hospital, University Medical Centre Utrecht, Post-Box 85090, 3508 AB Utrecht, The Netherlands.

Hepatology 2010 Jun;51(6):2049-60

Department of Membrane Enzymology, Bijvoet Center and Institute of Biomembranes, Utrecht University, the Netherlands.

Nat Genet 2010 Apr 28;42(4):295-302. Epub 2010 Feb 28.

Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

J Hepatol 2010 Feb 21;52(2):258-71. Epub 2009 Nov 21.

Department of Paediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands.

Hepatology 2010 Jan;51(1):286-96

Department of Metabolic and Endocrine Diseases, University Medical Center (UMC) Utrecht, The Netherlands.

Hepatology 2009 Dec;50(6):1783-95

Department of Metabolic and Endocrine Diseases, University Medical Center Utrecht, and the Netherlands Metabolomics Center, Utrecht, The Netherlands.

Hum Mol Genet 2009 Nov 31;18(21):4195-203. Epub 2009 Jul 31.

Department of Human Genetics, Institute for Genetic and Metabolic Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

J Pediatr 2009 Nov 14;155(5):629-33. Epub 2009 Aug 14.

Department of Pediatric Gastroenterology, University Medical Center Utrecht, Utrecht, The Netherlands.

Hepatology 2009 Nov;50(5):1442-52

Department of Neurology, University Medical Center, Utrecht, The Netherlands.

Proc Natl Acad Sci U S A 2009 Jun 28;106(24):9709-14. Epub 2009 May 28.

Department of Pediatric Gastroenterology, University Medical Center Utrecht, Utrecht, The Netherlands.

J Pediatr Gastroenterol Nutr 2009 May;48(5):566-70

Department of Paediatric Gastroenterology, University Medical Centre Utrecht, P.O. Box 85090, Utrecht 3508 AB, The Netherlands.

Pediatrics 2008 Apr;121(4):e857-63

Department of Pediatrics, Wilhelmina Children's Hospital, University Medical Center Utrecht, Lundlaan 6, 3584EA, Utrecht, The Netherlands.

Arch Dis Child 2007 Mar;92(3):250

Department of Paediatrics, Maxima Medical Centre, Veldhoven, The Netherlands.

J Cyst Fibros 2007 Jan 19;6(1):35-40. Epub 2006 Jun 19.

Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, P.O. Box 85090, 3508 AB Utrecht, The Netherlands.

J Pediatr Gastroenterol Nutr 2006 Nov;43(5):646-50

Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, UMC Utrecht, The Netherlands.

Hum Genet 2006 Oct 1;120(3):396-409. Epub 2006 Aug 1.

Section of Medical and Molecular Genetics, Norton Court, Birmingham Women's Hospital, University of Birmingham, B15 2TG, Edgbaston, Birmingham, UK.

J Pediatr 2006 Jul;149(1):144; author reply 144-5

Hepatology 2006 Jan;43(1):51-3

Department of Pediatric Gastroenterology, University Medical Center Utrecht, The Netherlands.

Pediatr Res 2004 Dec 20;56(6):981-7. Epub 2004 Oct 20.

Department of Pediatric Gastroenterology, University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands.

J Hepatol 2004 Nov;41(5):758-63

Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center, P.O. Box 85090, 3508 AB Utrecht, The Netherlands.

Eur J Hum Genet 2004 Sep;12(9):782-5

Department of Biomedical Genetics, University Medical Centre Utrecht, Utrecht, The Netherlands.

J Autoimmun 2004 Sep;23(2):183-90

Department of Biomedical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.

Gastroenterology 2004 Aug;127(2):379-84

Department of Metabolic and Endocrine Diseases, University Medical Center, Utrecht, The Netherlands.

J Pediatr Gastroenterol Nutr 2004 Jul;39(1):46-52

Emma Children's Hospital/Academic Medical Centre, Amsterdam, The Netherlands.

Hepatology 2004 Jul;40(1):27-38

Department of Metabolic and Endocrine Diseases, University Medical Center, Utrecht, The Netherlands.

Nat Genet 2004 Apr 28;36(4):400-4. Epub 2004 Mar 28.

Section of Medical and Molecular Genetics, University of Birmingham, and Liver Unit, Birmingham Children's Hospital, UK.

Am J Gastroenterol 2004 Mar;99(3):466-71

Department of Biomedical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.

Gastroenterology 2003 Oct;125(4):1032-41

Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.

Hepatology 2003 Sep;38(3):775-6; author reply 776-7

J Pediatr Gastroenterol Nutr 2003 Mar;36(3):407-9

Department of Pediatric Gastroenterolgy, Wilhelmina Children's Hospital, University Medical Center Utrecht, The Netherlands.

J Hepatol 2002 Mar;36(3):439-43

Department of Gastroenterology, Gastrointestinal Research Unit, University Medical Center, PO Box 85500, 3508, Utrecht GA, The Netherlands.