Robyn Sussman

Robyn Sussman

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Robyn Sussman

Robyn Sussman

Publications by authors named "Robyn Sussman"

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Development and Validation of Molecular Assays for Limited Tissue Samples.

Acta Cytol 2019 Apr 17:1-8. Epub 2019 Apr 17.

Center for Personalized Diagnostics, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA,

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https://www.karger.com/Article/FullText/499109
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http://dx.doi.org/10.1159/000499109DOI Listing
April 2019

Validation of a next-generation sequencing oncology panel optimized for low input DNA.

Cancer Genet 2018 12 19;228-229:55-63. Epub 2018 Sep 19.

Hospital of the University of Pennsylvania, Division of Precision and Computational Diagnostics, Department of Pathology & Laboratory Medicine, 3020 Market Street, Suite 220, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2018.08.004DOI Listing
December 2018

Differential killing of CD56-expressing cells by drug-conjugated human antibodies targeting membrane-distal and membrane-proximal non-overlapping epitopes.

MAbs 2016 May-Jun;8(4):799-810. Epub 2016 Feb 24.

a Protein Interactions Section, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute , Frederick , MD , USA.

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http://dx.doi.org/10.1080/19420862.2016.1155014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966860PMC
November 2017

Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma.

Cancer Cell 2017 09;32(3):295-309.e12

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Colket Translational Research Building, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600520PMC
September 2017

Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation.

Mol Cell 2017 Apr 11;66(2):247-257.e5. Epub 2017 Apr 11.

Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412717PMC
April 2017

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy.

Cancer Discov 2015 Dec 29;5(12):1282-95. Epub 2015 Oct 29.

Division of Cancer Pathobiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Immunology Graduate Group, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Cell & Molecular Biology Graduate Group, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Department of Pathology & Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/2159-8290.CD-15-1020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670800PMC
December 2015

USP22 regulates oncogenic signaling pathways to drive lethal cancer progression.

Cancer Res 2014 Jan 6;74(1):272-86. Epub 2013 Nov 6.

Authors' Affiliations: Departments of Cancer Biology, Urology, Radiation Oncology, Pathology, and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania; Sidney Kimmel Comprehensive Cancer Center; Department of Pathology, Johns Hopkins University, Baltimore, Maryland; and Institute of Biomedical Technology, University of Tampere and Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947329PMC
January 2014

The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2).

J Biol Chem 2013 Aug 12;288(33):24234-46. Epub 2013 Jun 12.

Department of Cancer Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1074/jbc.M113.469783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745368PMC
August 2013

Enzymatic assays for assessing histone deubiquitylation activity.

Methods 2011 Jul 12;54(3):339-47. Epub 2011 Apr 12.

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/j.ymeth.2011.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118937PMC
July 2011

Chemotherapy-resistant side-population of colon cancer cells has a higher sensitivity to TRAIL than the non-SP, a higher expression of c-Myc and TRAIL-receptor DR4.

Cancer Biol Ther 2007 Sep 17;6(9):1490-5. Epub 2007 Aug 17.

Laboratory of Molecular Oncology and Cell Cycle Regulation, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.4161/cbt.6.9.4905DOI Listing
September 2007