Robyn Reynolds

Robyn Reynolds

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Robyn Reynolds

Robyn Reynolds

Publications by authors named "Robyn Reynolds"

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Three new genetic loci (R1210C in CFH, variants in COL8A1 and RAD51B) are independently related to progression to advanced macular degeneration.

PLoS One 2014 31;9(1):e87047. Epub 2014 Jan 31.

Channing Laboratory, Brigham and Women's Hospital and Harvard School of Public Health, Harvard University, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087047PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909074PMC
October 2014

Whole-exome sequencing identifies rare, functional CFH variants in families with macular degeneration.

Hum Mol Genet 2014 Oct 20;23(19):5283-93. Epub 2014 May 20.

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, MA, USA Department of Ophthalmology, Tufts University School of Medicine, Boston, MA, USA Sackler School of Graduate Medical Sciences, Tufts University, Boston, MA, USA

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http://dx.doi.org/10.1093/hmg/ddu226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159152PMC
October 2014

Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration.

Nat Genet 2013 Nov 15;45(11):1366-70. Epub 2013 Sep 15.

1] Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, Massachusetts, USA. [2] Department of Ophthalmology, Tufts University School of Medicine, Boston, Massachusetts, USA. [3] Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.2741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902040PMC
November 2013

Dietary omega-3 fatty acids, other fat intake, genetic susceptibility, and progression to incident geographic atrophy.

Ophthalmology 2013 May 5;120(5):1020-8. Epub 2013 Mar 5.

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Department of Ophthalmology, Tufts Medical Center, Boston, Massachusetts 02111, USA.

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http://dx.doi.org/10.1016/j.ophtha.2012.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758110PMC
May 2013

Validation of a prediction algorithm for progression to advanced macular degeneration subtypes.

JAMA Ophthalmol 2013 Apr;131(4):448-55

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Tufts Medical Center, Boston, MA 02111, USA.

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http://dx.doi.org/10.1001/jamaophthalmol.2013.2578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547827PMC
April 2013

Seven new loci associated with age-related macular degeneration.

Authors:
Lars G Fritsche Wei Chen Matthew Schu Brian L Yaspan Yi Yu Gudmar Thorleifsson Donald J Zack Satoshi Arakawa Valentina Cipriani Stephan Ripke Robert P Igo Gabriëlle H S Buitendijk Xueling Sim Daniel E Weeks Robyn H Guymer Joanna E Merriam Peter J Francis Gregory Hannum Anita Agarwal Ana Maria Armbrecht Isabelle Audo Tin Aung Gaetano R Barile Mustapha Benchaboune Alan C Bird Paul N Bishop Kari E Branham Matthew Brooks Alexander J Brucker William H Cade Melinda S Cain Peter A Campochiaro Chi-Chao Chan Ching-Yu Cheng Emily Y Chew Kimberly A Chin Itay Chowers David G Clayton Radu Cojocaru Yvette P Conley Belinda K Cornes Mark J Daly Baljean Dhillon Albert O Edwards Evangelos Evangelou Jesen Fagerness Henry A Ferreyra James S Friedman Asbjorg Geirsdottir Ronnie J George Christian Gieger Neel Gupta Stephanie A Hagstrom Simon P Harding Christos Haritoglou John R Heckenlively Frank G Holz Guy Hughes John P A Ioannidis Tatsuro Ishibashi Peronne Joseph Gyungah Jun Yoichiro Kamatani Nicholas Katsanis Claudia N Keilhauer Jane C Khan Ivana K Kim Yutaka Kiyohara Barbara E K Klein Ronald Klein Jaclyn L Kovach Igor Kozak Clara J Lee Kristine E Lee Peter Lichtner Andrew J Lotery Thomas Meitinger Paul Mitchell Saddek Mohand-Saïd Anthony T Moore Denise J Morgan Margaux A Morrison Chelsea E Myers Adam C Naj Yusuke Nakamura Yukinori Okada Anton Orlin M Carolina Ortube Mohammad I Othman Chris Pappas Kyu Hyung Park Gayle J T Pauer Neal S Peachey Olivier Poch Rinki Ratna Priya Robyn Reynolds Andrea J Richardson Raymond Ripp Guenther Rudolph Euijung Ryu José-Alain Sahel Debra A Schaumberg Hendrik P N Scholl Stephen G Schwartz William K Scott Humma Shahid Haraldur Sigurdsson Giuliana Silvestri Theru A Sivakumaran R Theodore Smith Lucia Sobrin Eric H Souied Dwight E Stambolian Hreinn Stefansson Gwen M Sturgill-Short Atsushi Takahashi Nirubol Tosakulwong Barbara J Truitt Evangelia E Tsironi André G Uitterlinden Cornelia M van Duijn Lingam Vijaya Johannes R Vingerling Eranga N Vithana Andrew R Webster H-Erich Wichmann Thomas W Winkler Tien Y Wong Alan F Wright Diana Zelenika Ming Zhang Ling Zhao Kang Zhang Michael L Klein Gregory S Hageman G Mark Lathrop Kari Stefansson Rando Allikmets Paul N Baird Michael B Gorin Jie Jin Wang Caroline C W Klaver Johanna M Seddon Margaret A Pericak-Vance Sudha K Iyengar John R W Yates Anand Swaroop Bernhard H F Weber Michiaki Kubo Margaret M Deangelis Thierry Léveillard Unnur Thorsteinsdottir Jonathan L Haines Lindsay A Farrer Iris M Heid Gonçalo R Abecasis

Nat Genet 2013 Apr 3;45(4):433-9, 439e1-2. Epub 2013 Mar 3.

Institute of Human Genetics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/ng.2578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739472PMC
April 2013

Genetic factors for choroidal neovascularization associated with high myopia.

Invest Ophthalmol Vis Sci 2012 Jul 27;53(8):5004-9. Epub 2012 Jul 27.

Faculté de Médecine Henri Mondor, Department of Ophthalmology, APHP-Assistance Publique Hôpitaux Paris, Groupe Hospitalier Albert Chenevier-Henri Mondor, University Paris Est, Creteil, France.

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http://dx.doi.org/10.1167/iovs.12-9538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410690PMC
July 2012

Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate Markov models.

Invest Ophthalmol Vis Sci 2012 Mar 21;53(3):1548-56. Epub 2012 Mar 21.

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Department of Ophthalmology, Tufts Medical Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1167/iovs.11-8657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339916PMC
March 2012

Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors.

Ophthalmology 2011 Nov 29;118(11):2203-11. Epub 2011 Sep 29.

Ophthalmic Epidemiology and Genetics Service, Tufts University School of Medicine and Tufts Medical Center, New England Eye Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.ophtha.2011.04.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097877PMC
November 2011

Automated discovery and quantification of image-based complex phenotypes: a twin study of drusen phenotypes in age-related macular degeneration.

Invest Ophthalmol Vis Sci 2011 Nov 25;52(12):9195-206. Epub 2011 Nov 25.

Institute for Vision Research, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1167/iovs.10-6793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302481PMC
November 2011

Kidney function, albuminuria and age-related macular degeneration in NHANES III.

Nephrol Dial Transplant 2011 Oct 21;26(10):3159-65. Epub 2011 Feb 21.

Division of Nephrology, Department of Medicine, Tufts Medical Center and Tufts University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1093/ndt/gfr022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247860PMC
October 2011

Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration.

Invest Ophthalmol Vis Sci 2011 Jun 28;52(7):4663-70. Epub 2011 Jun 28.

Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts Medical Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1167/iovs.10-7070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175969PMC
June 2011

ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration.

Am J Ophthalmol 2011 Feb 3;151(2):345-52.e3. Epub 2010 Dec 3.

Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.ajo.2010.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763907PMC
February 2011

Associations of smoking, body mass index, dietary lutein, and the LIPC gene variant rs10468017 with advanced age-related macular degeneration.

Mol Vis 2010 Nov 17;16:2412-24. Epub 2010 Nov 17.

Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, and Channing Laboratory, Brigham and Women's Hospital, Boston, MA 02111, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994762PMC
November 2010

Serum lipid biomarkers and hepatic lipase gene associations with age-related macular degeneration.

Ophthalmology 2010 Oct;117(10):1989-95

Ophthalmic Epidemiology and Genetics Service, New England Eye Center, Department of Ophthalmology, Tufts Medical Center, Boston, Massachusetts 02111, USA.

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http://dx.doi.org/10.1016/j.ophtha.2010.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081670PMC
October 2010

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

Proc Natl Acad Sci U S A 2010 Apr 12;107(16):7401-6. Epub 2010 Apr 12.

Center for Statistical Genetics, Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1073/pnas.0912702107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867722PMC
April 2010

Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes.

Invest Ophthalmol Vis Sci 2009 Dec 6;50(12):5818-27. Epub 2009 Aug 6.

Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts University School of Medicine, Tufts Medical Center, Boston, Massachusetts 02111, USA.

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http://dx.doi.org/10.1167/iovs.09-3928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826794PMC
December 2009

Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables.

Invest Ophthalmol Vis Sci 2009 May 30;50(5):2044-53. Epub 2008 Dec 30.

Ophthalmic Epidemiology and Genetics Service, Tufts University School of Medicine and Tufts Medical Center, Boston, Massachusetts 02111, USA.

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http://iovs.arvojournals.org/data/Journals/IOVS/932959/z7g00
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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.0
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http://dx.doi.org/10.1167/iovs.08-3064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772781PMC
May 2009

Peripheral retinal drusen and reticular pigment: association with CFHY402H and CFHrs1410996 genotypes in family and twin studies.

Invest Ophthalmol Vis Sci 2009 Feb 20;50(2):586-91. Epub 2008 Oct 20.

Ophthalmic Epidemiology and Genetics Service, Department of Ophthalmology, Tufts University School of Medicine and Tufts Medical Center, New England Eye Center, Boston, Massachusetts 02111, USA.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.0
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http://dx.doi.org/10.1167/iovs.08-2514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498874PMC
February 2009

Variation near complement factor I is associated with risk of advanced AMD.

Eur J Hum Genet 2009 Jan 6;17(1):100-4. Epub 2008 Aug 6.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/ejhg.2008.140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2985963PMC
January 2009

CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration.

Ophthalmology 2008 Jun;115(6):1019-25

Macular Degeneration Center, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016164200800103
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http://dx.doi.org/10.1016/j.ophtha.2008.01.036DOI Listing
June 2008

Variation in complement factor 3 is associated with risk of age-related macular degeneration.

Nat Genet 2007 Oct 2;39(10):1200-1. Epub 2007 Sep 2.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://www.nature.com/articles/ng2131
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http://dx.doi.org/10.1038/ng2131DOI Listing
October 2007

Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: comparison with ritonavir.

Clin Pharmacol Ther 2006 Mar 7;79(3):243-54. Epub 2006 Feb 7.

Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, and Tufts-New England Medical Center, Boston, Mass 02111, USA.

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http://dx.doi.org/10.1016/j.clpt.2005.11.009DOI Listing
March 2006

Ginkgo biloba does not alter clearance of flurbiprofen, a cytochrome P450-2C9 substrate.

J Clin Pharmacol 2006 Feb;46(2):214-21

Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA.

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http://dx.doi.org/10.1177/0091270005283465DOI Listing
February 2006