Robyn L Ward

Robyn L Ward

UNVERIFIED PROFILE

Are you Robyn L Ward?   Register this Author

Register author
Robyn L Ward

Robyn L Ward

Publications by authors named "Robyn L Ward"

Are you Robyn L Ward?   Register this Author

100Publications

1953Reads

36Profile Views

Evaluation of the transferability of survival calculators for stage II/III colon cancer across healthcare systems.

Int J Cancer 2019 07 20;145(1):132-142. Epub 2019 Jan 20.

Systems Biology and Personalised Medicine Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/ijc.32100
Publisher Site
http://dx.doi.org/10.1002/ijc.32100DOI Listing
July 2019

Scarcity of Recurrent Regulatory Driver Mutations in Colorectal Cancer Revealed by Targeted Deep Sequencing.

JNCI Cancer Spectr 2019 Jun 16;3(2):pkz012. Epub 2019 Apr 16.

Prince of Wales Clinical School and Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jncics/pkz012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649856PMC
June 2019

Predictors of care for patients with cancer of unknown primary site in three Australian hospitals.

Asia Pac J Clin Oncol 2018 Oct 3;14(5):e512-e520. Epub 2017 Nov 3.

Cancer Epidemiology Research Unit, Centre for Big Data Research in Health, University of New South Wales, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajco.12815DOI Listing
October 2018

Cost-effectiveness analysis of germ-line BRCA testing in women with breast cancer and cascade testing in family members of mutation carriers.

Genet Med 2018 09 4;20(9):985-994. Epub 2018 Jan 4.

Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/gim.2017.231DOI Listing
September 2018

Disruption of a -35 kb Enhancer Impairs CTCF Binding and Expression in Colorectal Cells.

Clin Cancer Res 2018 09 13;24(18):4602-4611. Epub 2018 Jun 13.

Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, UNSW Sydney, Sydney, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-17-3678DOI Listing
September 2018

Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.

Lancet Gastroenterol Hepatol 2018 09 2;3(9):635-643. Epub 2018 Jul 2.

Oxford Centre for Cancer Gene Research, Wellcome Trust Centre for Human Genetics, Oxford, UK; Genomic Medicine Theme, National Institute for Health Research Oxford Biomedical Research Centre, Wellcome Trust Centre for Human Genetics, Oxford, UK; Cancer Genetics and Evolution Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2468-1253(18)30117-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088509PMC
September 2018

Long-term survival in trastuzumab-treated patients with HER2-positive metastatic breast cancer: real-world outcomes and treatment patterns in a whole-of-population Australian cohort (2001-2016).

Breast Cancer Res Treat 2018 Aug 7;171(1):151-159. Epub 2018 May 7.

Medicines Policy Research Unit, Centre for Big Data Research in Health, UNSW, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-018-4804-0DOI Listing
August 2018

Quality and impact of eviQ Cancer Treatments Online (www.eviq.org.au): the medical oncologist's perspective.

Asia Pac J Clin Oncol 2018 Apr 25;14(2):e203-e210. Epub 2017 May 25.

Cabrini Health, Malvern, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajco.12689DOI Listing
April 2018

Trastuzumab for metastatic breast cancer: Real world outcomes from an Australian whole-of-population cohort (2001-2016).

Breast 2018 Apr 21;38:7-13. Epub 2017 Nov 21.

Medicines Policy Research Unit, Centre for Big Data Research in Health, UNSW, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.breast.2017.11.007DOI Listing
April 2018

Factors associated with participation in colorectal cancer screening in Australia: Results from the 45 and Up Study cohort.

Prev Med 2018 01 3;106:185-193. Epub 2017 Nov 3.

Prince of Wales Clinical School, University of NSW, New South Wales, Australia; Cancer Research Division, Cancer Council NSW, New South Wales, Australia; School of Public Health, Sydney Medical School, University of Sydney, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ypmed.2017.10.032DOI Listing
January 2018

Retrospective comparison of Australia's Pharmaceutical Benefits Scheme claims data with prescription data in HER2-positive early breast cancer patients, 2008-2012.

Public Health Res Pract 2017 Dec 7;27(5). Epub 2017 Dec 7.

Medicines Policy Research Unit, Centre for Big Data Research in Health, UNSW Sydney, Australia; Menzies Centre for Health Policy, University of Sydney, NSW, Australia; Faculty of Pharmacy, University of Sydney, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17061/phrp2751744DOI Listing
December 2017

Guidance for Modifying the Definition of Diseases: A Checklist.

JAMA Intern Med 2017 07;177(7):1020-1025

Centre for Research in Evidence Based Practice, Bond University, Gold Coast, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamainternmed.2017.1302DOI Listing
July 2017

Validation of specificity of antibodies for immunohistochemistry: the case of ROR2.

Virchows Arch 2017 Jan 8;470(1):99-108. Epub 2016 Sep 8.

Adult Cancer Program, Level 2, Metastasis Research Group, Lowy Cancer Research Centre and School of Women's and Children's Health, University of New South Wales, Sydney, NSW, 2052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-016-2019-5DOI Listing
January 2017

Defining the criteria for identifying constitutional epimutations.

Clin Epigenetics 2016 18;8:39. Epub 2016 Apr 18.

Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, UNSW Australia, Kensington, Sydney, New South Wales 2052 Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-016-0207-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835913PMC
December 2016

Erratum to: Validation of specificity of antibodies for immunohistochemistry: the case of ROR2.

Virchows Arch 2016 Dec 29;469(6):717. Epub 2016 Oct 29.

Adult Cancer Program, Level 2, Metastasis Research Group, Lowy Cancer Research Centre and School of Women's and Children's Health, University of New South Wales, Sydney, NSW, 2052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-016-2036-4DOI Listing
December 2016

Pathogenic germline MCM9 variants are rare in Australian Lynch-like syndrome patients.

Cancer Genet 2016 Nov 11;209(11):497-500. Epub 2016 Oct 11.

Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, UNSW Australia, Sydney, New South Wales 2052, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cancergen.2016.10.001DOI Listing
November 2016

ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration.

BMC Cancer 2016 07 20;16:508. Epub 2016 Jul 20.

Metastasis Research Group, Adult Cancer Program, School of Women's and Children's Health, Lowy Cancer Research Centre, UNSW Australia, Sydney, NSW, 2052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-016-2576-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955198PMC
July 2016

The molecular characteristics of colonic neoplasms in serrated polyposis: a systematic review and meta-analysis.

J Pathol Clin Res 2016 Jul 22;2(3):127-37. Epub 2016 Apr 22.

Prince of Wales Clinical School, University of New South WalesSydney, Australia; Office of the Deputy Vice-Chancellor (Research), University of QueenslandBrisbane, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cjp2.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958734PMC
July 2016

Understanding the Pathogenicity of Noncoding Mismatch Repair Gene Promoter Variants in Lynch Syndrome.

Hum Mutat 2016 May 18;37(5):417-26. Epub 2016 Mar 18.

Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, UNSW Australia, Sydney, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.22971DOI Listing
May 2016

The Impact of Mismatch Repair Status in Colorectal Cancer on the Decision to Treat With Adjuvant Chemotherapy: An Australian Population-Based Multicenter Study.

Oncologist 2016 05 23;21(5):618-25. Epub 2016 Mar 23.

Prince of Wales Clinical School, UNSW Australia, Sydney, New South Wales, Australia University of Queensland, St. Lucia, Queensland, Australia

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/theoncologist.2015-0530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861373PMC
May 2016

Establishing the clinical utility of epigenetic markers in cancer: many challenges ahead.

Epigenomics 2013 ;5(5):513-23

Adult Cancer Program, Lowy Cancer Research Centre & Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales 2052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi.13.53DOI Listing
April 2016

Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr.

Mol Cell Biol 2016 Apr 31;36(8):1222-36. Epub 2016 Mar 31.

Adult Cancer Program, Prince of Wales Clinical School, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia Department of Haematology, Prince of Wales Hospital, Sydney, NSW, Australia

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.01035-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836279PMC
April 2016

PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells.

Proc Natl Acad Sci U S A 2016 Apr 4;113(16):E2306-15. Epub 2016 Apr 4.

Lowy Cancer Research Centre, University of New South Wales (UNSW) Australia, Sydney, NSW 2052, Australia; The Prince of Wales Clinical School, UNSW Australia, Sydney, NSW 2052, Australia; Department of Haematology, The Prince of Wales Hospital, Sydney, NSW 2032, Australia

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1518244113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843430PMC
April 2016

A cryptic paracentric inversion of MSH2 exons 2-6 causes Lynch syndrome.

Carcinogenesis 2016 Jan 24;37(1):10-17. Epub 2015 Oct 24.

Adult Cancer Program , Lowy Cancer Research Centre and Prince of Wales Clinical School, UNSW Australia , Sydney New South Wales 2052 , Australia.

View Article

Download full-text PDF

Source
https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
Publisher Site
http://dx.doi.org/10.1093/carcin/bgv154DOI Listing
January 2016

TREATMENT SWITCHING IN CANCER TRIALS: ISSUES AND PROPOSALS.

Int J Technol Assess Health Care 2016 Jan;32(3):167-74

University of Queensland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S026646231600009XDOI Listing
January 2016

Mosaic Epigenetic Inheritance as a Cause of Early-Onset Colorectal Cancer.

JAMA Oncol 2015 Oct;1(7):953-7

Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia4Brian Wilson Chancellery, University of Queensland, Brisbane, Queensland, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaoncol.2015.1484DOI Listing
October 2015

Development and Use of Disease-Specific (Reference) Models for Economic Evaluations of Health Technologies: An Overview of Key Issues and Potential Solutions.

Pharmacoeconomics 2015 Aug;33(8):777-81

Divison of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Science Faculty, Utrecht University, PO Box 80 082, 3508 TB, Utrecht, The Netherlands,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40273-015-0274-yDOI Listing
August 2015

Health service utilisation and investigations before diagnosis of cancer of unknown primary (CUP): A population-based nested case-control study in Australian Government Department of Veterans' Affairs clients.

Cancer Epidemiol 2015 Aug 16;39(4):585-92. Epub 2015 Jun 16.

Adult Cancer Program, Prince of Wales Clinical School, University of New South Wales, NSW, Australia; Faculty of Pharmacy, University of Sydney, NSW, Australia; Sydney Medical School, School of Public Health, University of Sydney, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canep.2015.02.006DOI Listing
August 2015

Patterns of care and survival after a cancer of unknown primary (CUP) diagnosis: A population-based nested cohort study in Australian Government Department of Veterans' Affairs clients.

Cancer Epidemiol 2015 Aug 20;39(4):578-84. Epub 2015 Jun 20.

Adult Cancer Program, Prince of Wales Clinical School, University of New South Wales, NSW 2052, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canep.2015.02.007DOI Listing
August 2015

Lynch syndrome associated with two MLH1 promoter variants and allelic imbalance of MLH1 expression.

Hum Mutat 2015 Jun 17;36(6):622-30. Epub 2015 Apr 17.

Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, UNSW Australia, Sydney, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/humu.22785
Publisher Site
http://dx.doi.org/10.1002/humu.22785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682451PMC
June 2015

Cost of cancer care for patients undergoing chemotherapy: The Elements of Cancer Care study.

Asia Pac J Clin Oncol 2015 Jun 13;11(2):178-86. Epub 2015 Apr 13.

Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, UNSW Australia, Sydney, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajco.12354DOI Listing
June 2015

Single nucleotide polymorphism array profiling identifies distinct chromosomal aberration patterns across colorectal adenomas and carcinomas.

Genes Chromosomes Cancer 2015 May 27;54(5):303-14. Epub 2015 Feb 27.

Adult Cancer Program, Prince of Wales Clinical School, Lowy Cancer Research Centre, UNSW, Sydney, NSW 2052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22243DOI Listing
May 2015

Discrimination of pseudogene and parental gene DNA methylation using allelic bisulfite sequencing.

Methods Mol Biol 2014 ;1167:265-74

Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, University of New South Wales, Kensington, Sydney, NSW, 2227, Australia,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-0835-6_18DOI Listing
January 2015

Institutional biobanking: an integral part of contemporary pathology practice.

Pathology 2015 Jan;47(1):4-6

1Prince of Wales Clinical School, UNSW, Sydney 2Anatomical Pathology Department, South Eastern Area Laboratory Services (SEALS), NSW Health Pathology 3POW Cancer Centre, Prince of Wales Hospital, Sydney 4School of Medical Sciences, UNSW, Sydney, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PAT.0000000000000185DOI Listing
January 2015

The importance of distinguishing pseudogenes from parental genes.

Clin Epigenetics 2014 31;6(1):90. Epub 2014 Dec 31.

Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, UNSW, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-014-0033-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280768PMC
January 2015

Cohesin Rad21 mediates loss of heterozygosity and is upregulated via Wnt promoting transcriptional dysregulation in gastrointestinal tumors.

Cell Rep 2014 Dec 20;9(5):1781-1797. Epub 2014 Nov 20.

Differentiation and Transcription Laboratory, Peter MacCallum Cancer Centre (PMCC), East Melbourne, VIC 3002, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC 3000, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2014.10.059DOI Listing
December 2014

Nucleosome positioning is unaltered at MLH1 splice site mutations in cells derived from Lynch syndrome patients.

Clin Epigenetics 2014 13;6(1):32. Epub 2014 Dec 13.

Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, University of New South Wales, Sydney, NSW Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13148-014-0032-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272815PMC
December 2014

Altered promoter nucleosome positioning is an early event in gene silencing.

Epigenetics 2014 Oct;9(10):1422-30

a Adult Cancer Program; Lowy Cancer Research Center and Prince of Wales Clinical School; UNSW ; Sydney , Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/15592294.2014.970077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622968PMC
October 2014

Human papillomavirus (HPV) genotypes in an Australian sample of anal cancers.

Int J Cancer 2014 Aug 4;135(4):996-1001. Epub 2014 Feb 4.

Western Sydney Sexual Health Centre, University of Sydney, Westmead Hospital, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.28730DOI Listing
August 2014

Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia.

Epigenetics 2014 Aug 16;9(8):1092-100. Epub 2014 May 16.

Adult Cancer Program; Lowy Cancer Research Centre and Prince of Wales Clinical School; Sydney, NSW Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/epi.29222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164494PMC
August 2014

An audit of cancer of unknown primary notifications: A cautionary tale for population health research using cancer registry data.

Cancer Epidemiol 2014 Aug 11;38(4):460-4. Epub 2014 Jun 11.

Faculty of Pharmacy, University of Sydney, Australia; School of Public Health, University of Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canep.2014.05.004DOI Listing
August 2014

The evidence for functional non-CpG methylation in mammalian cells.

Epigenetics 2014 Jun 9;9(6):823-8. Epub 2014 Apr 9.

Adult Cancer Program; Lowy Cancer Research Centre and Prince of Wales Clinical School; University of New South Wales; Sydney, NSW Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/epi.28741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065179PMC
June 2014

The MLH1 c.-27C>A and c.85G>T variants are linked to dominantly inherited MLH1 epimutation and are borne on a European ancestral haplotype.

Eur J Hum Genet 2014 May 2;22(5):617-24. Epub 2013 Oct 2.

1] Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, Australia [2] Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2013.200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992563PMC
May 2014

Introducing research initiatives into healthcare: what do doctors think?

Biopreserv Biobank 2014 Apr;12(2):91-8

1 Prince of Wales Clinical School, University of New South Wales , Sydney, Australia .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/bio.2013.0069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995354PMC
April 2014

Minimal excess risk of cancer and reduced risk of death from cancer in Australian Department of Veterans' Affairs clients: a record linkage study.

Aust N Z J Public Health 2014 Feb;38(1):30-4

Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1753-6405.12168DOI Listing
February 2014

A decade of promises in personalised cancer medicine: is the honeymoon over?

Authors:
Robyn L Ward

Med J Aust 2014 Feb;200(3):132-3

Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5694/mja14.00018DOI Listing
February 2014

Reassembly of nucleosomes at the MLH1 promoter initiates resilencing following decitabine exposure.

PLoS Genet 2013 25;9(7):e1003636. Epub 2013 Jul 25.

Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1003636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723495PMC
January 2014

Prohibitin expression is associated with high grade breast cancer but is not a driver of amplification at 17q21.33.

Pathology 2013 12;45(7):629-36

*Sydney Medical School - Westmead, University of Sydney, Westmead †Westmead Institute for Cancer Research, Westmead ‡Westmead Millennium Institute, Westmead §Tissue Pathology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead ||Translational Oncology, Sydney West Cancer Network, Western Sydney and Nepean Blue Mountains Local Health Districts, Westmead ¶Anatomical Pathology, St Vincent's Hospital, Darlinghurst **Prince of Wales Clinical School, University of New South Wales, Randwick ††School of Medical Sciences University of New South Wales, Randwick ‡‡School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia §§Genetics Branch, National Cancer Institute, Bethesda MD USA ||||these authors contributed equally to this work.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00313025163147
Publisher Site
http://dx.doi.org/10.1097/PAT.0000000000000004DOI Listing
December 2013

The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis.

Int J Cancer 2013 Aug 10;133(4):779-87. Epub 2013 Jan 10.

Wnt Signaling & Metastasis Group, Lowy Cancer Research Centre and Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.27984DOI Listing
August 2013

Trastuzumab therapy in Australia: which patients with HER2+ metastatic breast cancer are assessed for cardiac function?

Breast 2013 Aug 9;22(4):482-7. Epub 2013 May 9.

Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09609776130009
Publisher Site
http://dx.doi.org/10.1016/j.breast.2013.04.011DOI Listing
August 2013

The Wnt gatekeeper SFRP4 modulates EMT, cell migration and downstream Wnt signalling in serous ovarian cancer cells.

PLoS One 2013 11;8(1):e54362. Epub 2013 Jan 11.

Wnt Signalling & Metastasis Group, Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054362PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543420PMC
July 2013

Population-based molecular screening for Lynch syndrome: implications for personalized medicine.

J Clin Oncol 2013 Jul 3;31(20):2554-62. Epub 2013 Jun 3.

Lowy Cancer Research Centre, Prince of Wales Hospital, Randwick NSW 2031, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2012.46.8454DOI Listing
July 2013

The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer.

BMC Cancer 2013 Apr 2;13:174. Epub 2013 Apr 2.

Adult Cancer Program, Level 2, Lowy Cancer Research Centre and Prince of Wales Clinical School, University of New South Wales, New South Wales 2052, Australia.

View Article

Download full-text PDF

Source
http://bmccancer.biomedcentral.com/articles/10.1186/1471-240
Publisher Site
http://dx.doi.org/10.1186/1471-2407-13-174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621642PMC
April 2013

Identification of constitutional MLH1 epimutations and promoter variants in colorectal cancer patients from the Colon Cancer Family Registry.

Genet Med 2013 Jan 9;15(1):25-35. Epub 2012 Aug 9.

Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Kensington, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/gim.2012.91DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908650PMC
January 2013

A reinvestigation of somatic hypermethylation at the PTEN CpG island in cancer cell lines.

Biol Proced Online 2012 Apr 10;14(1). Epub 2012 Apr 10.

Adult Cancer Program, Lowy Cancer Research Centre and Prince of Wales Clinical School, University of New South Wales, Sydney, NSW 2052, Australia.

View Article

Download full-text PDF

Source
http://biologicalproceduresonline.biomedcentral.com/articles
Publisher Site
http://dx.doi.org/10.1186/1480-9222-14-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342897PMC
April 2012

Mutated in colorectal cancer protein modulates the NFκB pathway.

Anticancer Res 2012 Jan;32(1):73-9

Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Sydney NSW 2010, Australia.

View Article

Download full-text PDF

Source
January 2012

Dominantly inherited constitutional epigenetic silencing of MLH1 in a cancer-affected family is linked to a single nucleotide variant within the 5'UTR.

Cancer Cell 2011 Aug;20(2):200-13

Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine at the University of New South Wales, NSW 2052, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2011.07.003DOI Listing
August 2011

A systematic review and meta-analysis of KRAS status as the determinant of response to anti-EGFR antibodies and the impact of partner chemotherapy in metastatic colorectal cancer.

Eur J Cancer 2011 Jun 5;47(9):1343-54. Epub 2011 May 5.

Lowy Cancer Centre and Prince of Wales Clinical School, Faculty of Medicine, University of NSW, NSW 2052, Australia.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S095980491100245
Publisher Site
http://dx.doi.org/10.1016/j.ejca.2011.03.031DOI Listing
June 2011

Quantitative analysis of tissue folate using ultra high-performance liquid chromatography tandem mass spectrometry.

Anal Biochem 2011 Apr 28;411(2):210-7. Epub 2010 Dec 28.

Prince of Wales Clinical School and Adult Cancer Program, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW 2052, Australia.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S000326971000820
Publisher Site
http://dx.doi.org/10.1016/j.ab.2010.12.033DOI Listing
April 2011

Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer.

Mod Pathol 2011 Mar 19;24(3):396-411. Epub 2010 Nov 19.

School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/modpathol2010212
Publisher Site
http://dx.doi.org/10.1038/modpathol.2010.212DOI Listing
March 2011

The role of BRCA mutation testing in determining breast cancer therapy.

Nat Rev Clin Oncol 2010 Dec 9;7(12):708-17. Epub 2010 Nov 9.

Jack Brockhoff Familial Cancer Centre, Peter MacCallum Cancer Centre, 10 St Andrews Place, East Melbourne, VIC 3002, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrclinonc.2010.175DOI Listing
December 2010

Detection of allelic imbalance in MLH1 expression by pyrosequencing serves as a tool for the identification of germline defects in Lynch syndrome.

Fam Cancer 2010 Sep;9(3):345-56

Medical Epigenetics Laboratory, Integrated Cancer Research Group, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, 2052, Australia.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10689-009-9314-0
Publisher Site
http://dx.doi.org/10.1007/s10689-009-9314-0DOI Listing
September 2010

Epimutations and cancer predisposition: importance and mechanisms.

Curr Opin Genet Dev 2010 Jun 31;20(3):290-8. Epub 2010 Mar 31.

Lowy Cancer Research Centre and Prince of Wales Clinical School, University of New South Wales, Kensington, New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gde.2010.02.005DOI Listing
June 2010

Standardizing care in medical oncology: are Web-based systems the answer?

Cancer 2009 Dec;115(23):5579-88

University of New South Wales Cancer Research Centre, University of New South Wales, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.24600DOI Listing
December 2009

Favoritism in DNA methylation.

Cancer Prev Res (Phila) 2009 Oct 29;2(10):847-9. Epub 2009 Sep 29.

Level 1, EBB POW Hospital, High Street, Randwick, 2031, Sydney, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1940-6207.CAPR-09-0178DOI Listing
October 2009

Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers.

Diagn Mol Pathol 2009 Jun;18(2):62-71

Medical Oncology Department, St Vincent's Hospital Sydney, Darlinghurst, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PDM.0b013e318182af52DOI Listing
June 2009

Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out.

Cancer Res 2009 Apr 7;69(8):3650-6. Epub 2009 Apr 7.

Department of Nephrology, Section of Preventive Medicine, Albert-Ludwigs University, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/content/early/2009/04/07/0
Web Search
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-08-4057DOI Listing
April 2009

Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer.

Cancer Res 2007 Oct;67(19):9107-16

Department of Medical Oncology, St. Vincent's Hospital, Victoria Street, Darlinghurst, New South Wales 2010, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-07-0869DOI Listing
October 2007

Trastuzumab and metastatic breast cancer: trastuzumab use in Australia--monitoring the effect of an expensive medicine access program.

J Clin Oncol 2007 Aug;25(24):3688-93

School of Medicine, University of New South Wales, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2007.11.2516DOI Listing
August 2007

Inheritance of a cancer-associated MLH1 germ-line epimutation.

N Engl J Med 2007 Feb;356(7):697-705

Department of Medical Oncology, St. Vincent's Hospital, Sydney, Australia.

View Article

Download full-text PDF

Source
http://www.nejm.org/doi/abs/10.1056/NEJMoa064522
Publisher Site
http://dx.doi.org/10.1056/NEJMoa064522DOI Listing
February 2007

Off-label use of medicines: consensus recommendations for evaluating appropriateness.

Med J Aust 2006 Nov;185(10):544-8

University of New South Wales, Sydney, NSW, Australia.

View Article

Download full-text PDF

Source
November 2006