Robin Lemmens

Robin Lemmens

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Robin Lemmens

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Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

Authors:
Duncan Wilson Gareth Ambler Keon-Joo Lee Jae-Sung Lim Masayuki Shiozawa Masatoshi Koga Linxin Li Caroline Lovelock Hugues Chabriat Michael Hennerici Yuen Kwun Wong Henry Ka Fung Mak Luis Prats-Sánchez Alejandro Martínez-Domeño Shigeru Inamura Kazuhisa Yoshifuji Ethem Murat Arsava Solveig Horstmann Jan Purrucker Bonnie Yin Ka Lam Adrian Wong Young Dae Kim Tae-Jin Song Maarten Schrooten Robin Lemmens Sebastian Eppinger Thomas Gattringer Ender Uysal Zeynep Tanriverdi Natan M Bornstein Einor Ben Assayag Hen Hallevi Jun Tanaka Hideo Hara Shelagh B Coutts Lisa Hert Alexandros Polymeris David J Seiffge Philippe Lyrer Ale Algra Jaap Kappelle Rustam Al-Shahi Salman Hans R Jäger Gregory Y H Lip Heinrich P Mattle Leonidas D Panos Jean-Louis Mas Laurence Legrand Christopher Karayiannis Thanh Phan Sarah Gunkel Nicolas Christ Jill Abrigo Thomas Leung Winnie Chu Francesca Chappell Stephen Makin Derek Hayden David J Williams M Eline Kooi Dianne H K van Dam-Nolen Carmen Barbato Simone Browning Kim Wiegertjes Anil M Tuladhar Noortje Maaijwee Christine Guevarra Chathuri Yatawara Anne-Marie Mendyk Christine Delmaire Sebastian Köhler Robert van Oostenbrugge Ying Zhou Chao Xu Saima Hilal Bibek Gyanwali Christopher Chen Min Lou Julie Staals Régis Bordet Nagaendran Kandiah Frank-Erik de Leeuw Robert Simister Aad van der Lugt Peter J Kelly Joanna M Wardlaw Yannie Soo Felix Fluri Velandai Srikanth David Calvet Simon Jung Vincent I H Kwa Stefan T Engelter Nils Peters Eric E Smith Yusuke Yakushiji Dilek Necioglu Orken Franz Fazekas Vincent Thijs Ji Hoe Heo Vincent Mok Roland Veltkamp Hakan Ay Toshio Imaizumi Beatriz Gomez-Anson Kui Kai Lau Eric Jouvent Peter M Rothwell Kazunori Toyoda Hee-Joon Bae Joan Marti-Fabregas David J Werring

Lancet Neurol 2019 Jul 23;18(7):653-665. Epub 2019 May 23.

Stroke Research Centre, Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(19)30197-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562236PMC
July 2019

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2019 Jul;51(7):1192-1193

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-019-0449-0DOI Listing
July 2019

Anticoagulation in low-risk patients with atrial fibrillation: beyond prevention of ischaemic stroke.

Eur Heart J 2019 Jul;40(28):2336-2338

KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology, Leuven, Belgium.

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http://dx.doi.org/10.1093/eurheartj/ehz414DOI Listing
July 2019

Reduction of ephrin-A5 aggravates disease progression in amyotrophic lateral sclerosis.

Acta Neuropathol Commun 2019 Jul 12;7(1):114. Epub 2019 Jul 12.

Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), KU Leuven - University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1186/s40478-019-0759-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626434PMC
July 2019

Cerebrovascular events after surgery versus conservative therapy for moyamoya disease: a meta-analysis.

Acta Neurol Belg 2019 Jun 18. Epub 2019 Jun 18.

Department of Neurosciences, Experimental Neurology, KU Leuven, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1007/s13760-019-01165-9DOI Listing
June 2019

Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source.

N Engl J Med 2019 05;380(20):1906-1917

From the University Duisburg-Essen and University Hospital Essen, Essen (H.-C.D.), Boehringer Ingelheim Pharma GmbH K.G., Biberach (C.G.), Boehringer Ingelheim International GmbH, Ingelheim, Faculty of Medicine Mannheim of the University of Heidelberg, Mannheim (M.B.), Kreisklinikum Siegen, Siegen, and the University of Marburg, Marburg (M.G.), University Hospital Erlangen, Erlangen (B.K.), and Johannes Wesling Klinikum Minden and Ruhr University Bochum, Minden (P.D.S.) - all in Germany; Miller School of Medicine, University of Miami, Miami (R.L.S.); University of California at San Francisco, San Francisco (J.D.E.), and the Department of Neurology and Comprehensive Stroke Center, University of California at Los Angeles, Los Angeles (J.L.S.) - both in California; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC (C.B.G.); Feinberg School of Medicine of Northwestern University, Chicago (R.A.B.); International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Sanno Medical Center, Tokyo (S.U.), and the National Cerebral and Cardiovascular Center, Osaka (K.T.) - both in Japan; Boehringer Ingelheim, Singapore, Singapore (J. Kreuzer); Boehringer Ingelheim, Burlington, ON, Canada (L.C.); Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT (D.C.); City Clinical Emergency Care Hospital, Kursk (M.C.), and the Military Medical Academy, St. Petersburg (M.O.) - both in Russia; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia (G.D.); Serviço de Neurologia, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Instituto de Medicina Molecular, University of Lisbon, Lisbon, Portugal (J.M.F.); F. Ass. Mutua Terrassa, Terrassa (J. Krupinski), and Servicio de Neurología, Hospital Universitario Ramón y Cajal (IRYCIS), Departamento de Medicina, Universidad de Alcalá, Madrid (J.M.) - both in Spain; Hallym University Sacred Heart Hospital, Seoul, South Korea (B.-C.L.); KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology, VIB Center for Brain & Disease Research, University Hospitals Leuven, Department of Neurology, Leuven, Belgium (R.L.); and Hospital Policlinico Umberto I, Sapienza University, Rome (D.T.).

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http://dx.doi.org/10.1056/NEJMoa1813959DOI Listing
May 2019

Hospital case-volume is associated with case-fatality after aneurysmal subarachnoid hemorrhage.

Int J Stroke 2019 04 18;14(3):282-289. Epub 2018 Jul 18.

1 Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1177/1747493018790073DOI Listing
April 2019

Heterozygous Deletion of EphrinA5 Does Not Improve Functional Recovery After Experimental Stroke.

Stroke 2019 Apr;50(4):e101

From the KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute (LBI), Belgium (A.d.B., A.S., L.R., L.P., W.R., R.L.).

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http://dx.doi.org/10.1161/STROKEAHA.118.023857DOI Listing
April 2019

Torsional internuclear ophthalmoplegia in acute ischemic stroke.

Neurol Clin Pract 2019 Apr;9(2):168-169

Department of Neurology, University Hospitals Leuven, Belgium.

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http://dx.doi.org/10.1212/CPJ.0000000000000569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461415PMC
April 2019

Genetic variation in is associated with white matter hyperintensities (n = 11,226).

Neurology 2019 02 18;92(8):e749-e757. Epub 2019 Jan 18.

From the Department of Clinical Neurosciences, Stroke Research Group (M.T., D.J.T., I.D.C., D.M.L.F., A.O.O., L.R.-J., H.S.M.), University of Cambridge, UK; Department of Cerebrovascular Diseases (G.B.), Fondazione IRCCS Istituto Neurologico "Carlo Besta," Milan, Italy; Institute for Stroke and Dementia Research (M.D.), Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich; German Center for Neurodegenerative Diseases (DZNE) and Munich Cluster for Systems Neurology (SyNergy) (M.D.), Germany; Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND) (R.L.), KU Leuven-University of Leuven; Department of Neurology (R.L.), University Hospitals Leuven; Laboratory of Neurobiology (R.L.), VIB Center for Brain and Disease Research, Leuven, Belgium; Center for Human Genetic Research (J.R.) and Division of Neurocritical Care and Emergency Neurology (J.R.) and J. Philip Kistler Stroke Research Center (J.R., N.S.R.), Department of Neurology, Massachusetts General Hospital, Boston; Nuffield Department of Clinical Neurosciences (Clinical Neurology), Stroke Prevention Research Unit (P.M.R.), University of Oxford; Centre for Clinical Brain Sciences and Institute for Genetics and Molecular Medicine (C.L.M.S.), University of Edinburgh, UK; Stroke Division, Florey Institute of Neuroscience and Mental Health (V.T.), University of Melbourne; and Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000006952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396967PMC
February 2019

Diagnostic accuracy of noncontrast CT imaging markers in cerebral venous thrombosis.

Neurology 2019 Feb 18;92(8):e841-e851. Epub 2019 Jan 18.

From the Departments of Radiology (P.-J.B., P.D.) and Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (S.M.Z., J.M.C.), Amsterdam University Medical Centers, Amsterdam, the Netherlands; Department of Neurology (C.-G.E.), John Hunter Hospital, University of Newcastle, Australia; Stroke Department (M.A.B., A.A.), Instituto Nacional de Neurología y Neurocirugía Dr. Manuel Velasco Suárez, México City, México; Department of Head and Neck (P.C.), Neurology Unit, Fondazione Poliambulanza, Brescia, Italy; Departments of Head and Neck (P.C.) and Clinical and Experimental Sciences (A.P.), Neurology Clinic, University of Brescia, Italy; Neurology Department (I.E., J.M.), University Hospitals Virgen del Rocio and Macarena, Seville; Neurovascular Lab (I.E., J.M.), Instituto de Biomedicina de Sevilla, Spain; Department of Neurology (D.R.), Nîmes University Hospital, France; Department of Neurosciences (R.L.), Experimental Neurology and Leuven Institute for Neuroscience and Disease (LIND), KU Leuven-University of Leuven; Laboratory of Neurobiology (R.L.), Center for Brain & Disease Research, VIB, Leuven, Belgium; Departments of Radiology (N.H.) and Neurology (F.F., T.G.), Medical University of Graz, Austria; Department of Neurology (J.J.C., E.G.-S.), Neurovascular Research Group, IMIM-Hospital del Mar, Barcelona; Universitat Autònoma de Barcelona (J.J.C., E.G.-S.), Spain; Department of Neurology (S.H., J.P., T.T.), Helsinki University Hospital, Finland; Department of Neurology (J.M.), Hospital Universitario Virgen Macarena, Seville, Spain; Department of Neurology (C.W.), University Hospital Essen, Germany; The Florey Institute of Neuroscience and Mental Health (L.C.), University of Melbourne; Australia School of Medicine (H.A.), Faculty of Health, Deakin University; Interventional Neuroradiology Service (H.A.), Radiology Department, Austin Health, Melbourne; Interventional Neuroradiology Service (H.A.), Radiology Department, Monash Health, Melbourne, Australia; Department of Clinical Neuroscience/Neurology (T.T.), Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg; Department of Neurology (T.T.), Sahlgrenska University Hospital, Gothenburg, Sweden; Stroke Division, Florey Institute of Neuroscience and Mental Health (V.T.), University of Melbourne, Heidelberg; and Department of Neurology (V.T.), Austin Health, Heidelberg, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000006959DOI Listing
February 2019

PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome.

Circ Res 2019 Jan;124(1):114-120

From the Department of Neurology, Neurovascular Research Group, Hospital del Mar Medical Research Institute, Universitat Autònoma de Barcelona/DCEXS-Universitat Pompeu Fabra (M.M.-C., C.S.-T., E.G.-S., A.R.-C., A.O., E.C.-G., R.M.V.-H., J.R., J.J.-C.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.31353
Publisher Site
http://dx.doi.org/10.1161/CIRCRESAHA.118.313533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501820PMC
January 2019

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Authors:
Ganesh Chauhan Hieab H H Adams Claudia L Satizabal Joshua C Bis Alexander Teumer Muralidharan Sargurupremraj Edith Hofer Stella Trompet Saima Hilal Albert Vernon Smith Xueqiu Jian Rainer Malik Matthew Traylor Sara L Pulit Philippe Amouyel Bernard Mazoyer Yi-Cheng Zhu Sara Kaffashian Sabrina Schilling Gary W Beecham Thomas J Montine Gerard D Schellenberg Olafur Kjartansson Vilmundur Guðnason David S Knopman Michael E Griswold B Gwen Windham Rebecca F Gottesman Thomas H Mosley Reinhold Schmidt Yasaman Saba Helena Schmidt Fumihiko Takeuchi Shuhei Yamaguchi Toru Nabika Norihiro Kato Kumar B Rajan Neelum T Aggarwal Philip L De Jager Denis A Evans Bruce M Psaty Jerome I Rotter Kenneth Rice Oscar L Lopez Jiemin Liao Christopher Chen Ching-Yu Cheng Tien Y Wong Mohammad K Ikram Sven J van der Lee Najaf Amin Vincent Chouraki Anita L DeStefano Hugo J Aparicio Jose R Romero Pauline Maillard Charles DeCarli Joanna M Wardlaw Maria Del C Valdés Hernández Michelle Luciano David Liewald Ian J Deary John M Starr Mark E Bastin Susana Muñoz Maniega P Eline Slagboom Marian Beekman Joris Deelen Hae-Won Uh Robin Lemmens Henry Brodaty Margaret J Wright David Ames Giorgio B Boncoraglio Jemma C Hopewell Ashley H Beecham Susan H Blanton Clinton B Wright Ralph L Sacco Wei Wen Anbupalam Thalamuthu Nicola J Armstrong Elizabeth Chong Peter R Schofield John B Kwok Jeroen van der Grond David J Stott Ian Ford J Wouter Jukema Meike W Vernooij Albert Hofman André G Uitterlinden Aad van der Lugt Katharina Wittfeld Hans J Grabe Norbert Hosten Bettina von Sarnowski Uwe Völker Christopher Levi Jordi Jimenez-Conde Pankaj Sharma Cathie L M Sudlow Jonathan Rosand Daniel Woo John W Cole James F Meschia Agnieszka Slowik Vincent Thijs Arne Lindgren Olle Melander Raji P Grewal Tatjana Rundek Kathy Rexrode Peter M Rothwell Donna K Arnett Christina Jern Julie A Johnson Oscar R Benavente Sylvia Wasssertheil-Smoller Jin-Moo Lee Quenna Wong Braxton D Mitchell Stephen S Rich Patrick F McArdle Mirjam I Geerlings Yolanda van der Graaf Paul I W de Bakker Folkert W Asselbergs Velandai Srikanth Russell Thomson Rebekah McWhirter Chris Moran Michele Callisaya Thanh Phan Loes C A Rutten-Jacobs Steve Bevan Christophe Tzourio Karen A Mather Perminder S Sachdev Cornelia M van Duijn Bradford B Worrall Martin Dichgans Steven J Kittner Hugh S Markus Mohammad A Ikram Myriam Fornage Lenore J Launer Sudha Seshadri W T Longstreth Stéphanie Debette

Neurology 2019 Jan 16. Epub 2019 Jan 16.

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http://dx.doi.org/10.1212/WNL.0000000000006851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369905PMC
January 2019

MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset.

N Engl J Med 2018 08 16;379(7):611-622. Epub 2018 May 16.

From Klinik und Poliklinik für Neurologie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf (G.T., B. Cheng, S.G., A.G., C.G.), the Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf (J.F.), and ZytoService Deutschland (E.S.), Hamburg, Universitätsklinik für Neurologie, Medizinische Universität Graz, Graz (F.F.), Centrum für Schlaganfallforschung Berlin (I.G., K.G.H., K.V., M. Ebinger, M. Endres, J.B.F.) and Klinik und Hochschulambulanz für Neurologie (K.G.H., L.N., M. Endres), Charité-Universitätsmedizin Berlin, and Neurologie der Rehaklinik Medical Park Humboldtmühle (M. Ebinger), Berlin, Mediri (J. Gregori, M.G.), the Department of Neurology, Medical Faculty Mannheim, University of Heidelberg (M.H.), and Neurologische Klinik, Universitätsklinikum Heidelberg (P. Ringleb), Heidelberg, Fraunhofer MEVIS and University of Bremen, Bremen (M.G.), and Institut für Neuroradiologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck (A.K.) - all in Germany; the Department of Neurology, Aarhus University Hospital, Aarhus (C.Z.S., G.A.), the Department of Neurology, Bispebjerg Hospital, Copenhagen University Hospital, Copenhagen (J.M.), and Department of Neurology, Stroke Unit, Aalborg University Hospital, Aalborg (B.M.) - all in Denmark; Hospices Civils de Lyon, Service de Biostatistique (F.B., P. Roy), the Neuroradiology Department, Neurological Hospital, University Lyon (Y.B.), and the Department of Stroke Medicine, Université Claude Bernard Lyon 1, and Hospices Civils de Lyon (T.-H.C., N.N.), Lyon, and Université Lyon 1 and Centre National de la Recherche Scientifique, UMR 5558, Laboratoire de Biométrie et Biologie Evolutive, Equipe Biostatistique-Santé, Villeurbanne (F.B., P. Roy) - all in France; the Institute of Neuroscience and Psychology (B. Cheripelli, K.W.M.) and the Robertson Centre for Biostatistics (I.F.), University of Glasgow, Glasgow, United Kingdom (I.F.); Fundació Salut Empordà Hospital, Figueres (J. Guibernau), Stroke Unit, Department of Neurosciences, Hospital Universitari Germans Trias i Pujol, Barcelona (N.P.O.), and the Department of Radiology (J.P., S.P.) and the Stroke Unit (J.S.), Hospital Universitari Doctor Josep Trueta, Institut d'Investigació Biomèdica de Girona, Girona - all in Spain; the Department of Neurology, St. Antonius Hospital, Nieuwegein, and University Medical Center Utrecht, Utrecht (W.S.) - both in the Netherlands; the Department of Imaging and Pathology, University of Leuven (S.S.), the Department of Neurology, University Hospitals Leuven (A.W., R.L.), KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology (A.W., R.L.), and the VIB-KU Leuven Center for Brain and Disease Research, Laboratory of Neurobiology (A.W., R.L.), Leuven, Belgium; and Florey Institute of Neuroscience and Mental Health, Heidelberg, VIC, Australia (V.T.).

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http://dx.doi.org/10.1056/NEJMoa1804355DOI Listing
August 2018

Multimodal magnetic resonance imaging to identify stroke onset within 6 h in patients with large vessel occlusions.

Eur Stroke J 2018 Jun 1;3(2):185-192. Epub 2018 Feb 1.

Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1177/2396987317753486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460412PMC
June 2018

Automated DWI analysis can identify patients within the thrombolysis time window of 4.5 hours.

Neurology 2018 05 4;90(18):e1570-e1577. Epub 2018 Apr 4.

From the Departments of Neurosciences (A.W., R. Lemmens), Cognitive Neurology (P.D.), and Electrical Engineering (D.R.), KU Leuven, University of Leuven; VIB Center for Brain & Disease Research (A.W., R. Lemmens); Department of Neurology (A.W., R. Lemmens), University Hospitals Leuven, Leuven, Belgium; Department of Neurology (B.C., G.T.), University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Stanford Stroke Center (S.C., G.W.A.), Stanford University Medical Center, Palo Alto, CA; Department of Neurology (B.N.), Lund University, Sweden; Guided Development GmbH (R. Laage), Heidelberg, Germany; and Florey Institute of Neuroscience and Mental Health (V.N.T.), Heidelberg, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000005413DOI Listing
May 2018

Prediction of Outcome in Patients With Acute Ischemic Stroke Based on Initial Severity and Improvement in the First 24 h.

Front Neurol 2018 7;9:308. Epub 2018 May 7.

Department of Neurosciences, Experimental Neurology, KU Leuven - University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.3389/fneur.2018.00308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950843PMC
May 2018

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2018 04 12;50(4):524-537. Epub 2018 Mar 12.

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-018-0058-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968830PMC
April 2018

Are there opportunities for a closer collaboration on clinical stroke research in Europe?

Eur Stroke J 2018 Mar 11;3(1):22-28. Epub 2017 Dec 11.

Stroke Service, Mater University Hospital, and Stroke Clinical Trials Network Ireland, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1177/2396987317747456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453236PMC
March 2018

Anti-inflammatory approaches to ischaemic stroke prevention.

J Neurol Neurosurg Psychiatry 2018 02 21;89(2):211-218. Epub 2017 Sep 21.

Institute of Neuroscience, Newcastle University, Newcastle, UK.

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http://dx.doi.org/10.1136/jnnp-2016-314817DOI Listing
February 2018

The Role of Colchicine in the Prevention of Cerebrovascular Ischemia.

Curr Pharm Des 2018 ;24(6):668-674

Health Research Board Irish Stroke Clinical Trials Network and Mater University Hospital/ University College Dublin, Ireland.

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http://www.eurekaselect.com/159083/article
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http://dx.doi.org/10.2174/1381612824666180116100310DOI Listing
January 2018

Moyamoya disease and systemic sclerosis (MoSys syndrome): a combination of two rare entities: comment to the authors.

Clin Exp Rheumatol 2017 Sep-Oct;35 Suppl 106(4):216. Epub 2017 Feb 23.

Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), Leuven; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven; and Department of Neurology, Leuven, Belgium.

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December 2017

Non-REM sleep EEG pattern in acute bithalamic paramedian infarction.

Acta Neurol Belg 2017 12 20;117(4):921-924. Epub 2017 May 20.

Department of Neurology, University Hospitals Leuven, Herestraat 49, B-3000, Louvain, Belgium.

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http://dx.doi.org/10.1007/s13760-017-0783-xDOI Listing
December 2017

Brain microbleeds, anticoagulation, and hemorrhage risk: Meta-analysis in stroke patients with AF.

Neurology 2017 Dec 8;89(23):2317-2326. Epub 2017 Nov 8.

From the J. Philip Kistler Stroke Research Center (A.C.), Department of Neurology, Massachusetts General Hospital; Harvard Medical School (A.C.), Boston, MA; META-MICROBLEEDS Initiative/Consortium (A.C.); Stroke and Ageing Research Centre (C.K., S.M.G., T.G.P., R.V.C., V.S.), Department of Medicine, School for Clinical Sciences at Monash Health, Monash University, Melbourne, Australia; Department of Neurology (J.H.H.), Yonsei University College of Medicine, Seoul, Korea; Sisli Hamidiye Etfal Education and Research Hospital (D.N.O.), Department of Neurology, Istanbul, Turkey; Department of Neurology (V.T.), Austin Health and Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria, Australia; Department of Neurology (J.K.), CHA Bundang Medical Centre, CHA University, Seongnam, Korea; Stroke Unit (T.G.P., V.S.), Neurosciences, and Neuroradiology Service (C.S., R.V.C., L.-A.S.), Monash Imaging, Monash Health, Melbourne, Australia; Department of Neurology (S.H.), Mayo Clinic, Rochester, MN; Department of Medicine and Therapeutics (V.M., K.T.L., L.K.S.W., Y.S.), Chinese University of Hong Kong; Department of Neurology (S.H., R.V., T.I.), University of Heidelberg, Germany; Department of Internal Medicine (Y.K., N.S., N.H., T.S.), Cardiovascular, Respiratory and Neurology Division, Asahikawa Medical University, Japan; Department of Stroke Medicine (R.V.), Division of Brain Sciences, Imperial College London, UK; Department of Neurosurgery (K.D.F.), Kushiro City General Hospital, Hokkaido, Japan; KU Leuven-University of Leuven (R.L.), Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease; VIB (R.L.), Vesalius Research Center, Laboratory of Neurobiology; University Hospitals Leuven (R.L.), Department of Neurology, Belgium; and Department of Neurology (T.-J.S.), College of Medicine, Ewha Woman's University, Yangcheon-gu, Seoul, Korea.

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http://dx.doi.org/10.1212/WNL.0000000000004704DOI Listing
December 2017

Unknown onset ischemic strokes in patients last-seen-well >4.5 h: differences between wake-up and daytime-unwitnessed strokes.

Acta Neurol Belg 2017 Sep 12;117(3):637-642. Epub 2017 Aug 12.

Department of Neurology, Haaglanden Medical Center, Lijnbaan 32, 2512 VA, The Hague, The Netherlands.

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http://dx.doi.org/10.1007/s13760-017-0830-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565646PMC
September 2017

Effect of informed consent on patient characteristics in a stroke thrombolysis trial.

Neurology 2017 Sep 25;89(13):1400-1407. Epub 2017 Aug 25.

From Klinik und Poliklinik für Neurologie, Kopf- und Neurozentrum (G.T., C.H., B.C., C.G.), and Klinik und Poliklinik für Neuroradiologische Diagnostik und Intervention, Diagnostikzentrum (J.F.), Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany; Service de Biostatistique (F.B., P.R.) and Department of Neurology (N.N., T.-H.C.), Hospices Civils de Lyon; Université Lyon 1 (F.B., P.R.), Villeurbanne; CNRS, UMR 5558 (F.B., P.R.), Laboratoire de Biométrie et Biologie Evolutive, Equipe Biostatistique-Santé, Villeurbanne, France; Centrum für Schlaganfallforschung Berlin (CSB) (J.B.F., M. Ebinger, M. Endres) and Klinik und Hochschulambulanz für Neurologie (M. Ebinger, M. Endres), Charité-Universitätsmedizin Berlin, Germany; Department of Neurology (C.Z.S.), Aarhus University Hospital, Denmark; Department of Radiology (S.P., J.P.), Institut de Diagnostic per la Image (IDI), Hospital Dr Josep Trueta, Institut d'Investgació Biomèdica de Girona (IDIBGI), Girona, Spain; Department of Neurosciences, Experimental Neurology, and Leuven Research Institute for Neuroscience and Disease (LIND) (R.L.), KU Leuven-University of Leuven; VIB, Laboratory of Neurobiology (R.L.), Center for Brain & Disease Research, Leuven; Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Institute of Neuroscience & Psychology (K.W.M.) and Robertson Centre for Biostatistics (I.F.), University of Glasgow, UK; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health; and Department of Neurology (V.T.), Austin Health, Heidelberg, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000004414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649757PMC
September 2017

Postoperative atrial fibrillation: Target for stroke prevention?

Eur Stroke J 2017 Sep 5;2(3):222-228. Epub 2017 Jul 5.

Department of Cardiology, University Hospitals Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1177/2396987317719363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454826PMC
September 2017

Pocket Pain and Neuromodulation: Negligible or Neglected?

Neuromodulation 2017 Aug 12;20(6):600-605. Epub 2017 Jul 12.

Department of Neurosurgery, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1111/ner.12637DOI Listing
August 2017

Individualized risk prediction of major bleeding in secondary stroke prevention: Are we there yet?

Neurology 2017 08 2;89(9):882-883. Epub 2017 Aug 2.

From the Department of Neurosciences (R.L.), Experimental Neurology and Leuven Institute for Neuroscience and Disease (LIND), KU Leuven-University of Leuven; Laboratory of Neurobiology (R.L.), Center for Brain & Disease Research, VIB, Leuven; Department of Neurology (R.L.), University Hospitals Leuven, Belgium; and Centre for Clinical Brain Sciences (R.A.S.), University of Edinburgh, UK.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000004303DOI Listing
August 2017

Identification and characterization of Nanobodies targeting the EphA4 receptor.

J Biol Chem 2017 07 19;292(27):11452-11465. Epub 2017 May 19.

From the KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), 3000 Leuven, Belgium,

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http://dx.doi.org/10.1074/jbc.M116.774141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500810PMC
July 2017

Internal carotid artery dissection coincides with celiac artery dissection.

Acta Neurol Belg 2017 03 5;117(1):333-335. Epub 2016 Aug 5.

Department of Neurology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1007/s13760-016-0681-7DOI Listing
March 2017

Stroke With Unknown Time of Symptom Onset: Baseline Clinical and Magnetic Resonance Imaging Data of the First Thousand Patients in WAKE-UP (Efficacy and Safety of MRI-Based Thrombolysis in Wake-Up Stroke: A Randomized, Doubleblind, Placebo-Controlled Trial).

Stroke 2017 03 7;48(3):770-773. Epub 2017 Feb 7.

From the Klinik und Poliklinik für Neurologie, Kopf- und Neurozentrum (G.T., B.C., C.G.) and Klinik und Poliklinik für Neuroradiologische Diagnostik und Intervention, Diagnostikzentrum (J.F.), Universitätsklinikum Hamburg-Eppendorf, Germany; Service de Biostatistique, Hospices Civils de Lyon, France (F.B., P.R.); Université Lyon 1, Villeurbanne, France (F.B., P.R.); CNRS, UMR 5558, Laboratoire de Biométrie et Biologie Evolutive, Equipe Biostatistique-Santé, Villeurbanne, France (F.B., P.R.); Centrum für Schlaganfallforschung Berlin (CSB) (J.B.F., I.G., M. Ebinger, M. Endres) and Klinik und Hochschulambulanz für Neurologie (M. Ebinger, M. Endres), Charité-Universitätsmedizin Berlin, Germany; Department of Neurology, Aarhus University Hospital, Denmark (C.Z.S.); Department of Neurology, Hospices Civils de Lyon, France (N.N., T.-H.C.); Department of Radiology, Institut de Diagnostic per la Image (IDI), Hospital Dr Josep Trueta, Institut d'Investgació Biomèdica de Girona (IDIBGI), Spain (S.P., J.P.); Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, VIB Center for Brain & Disease Research, and Department of Neurology, University Hospitals Leuven, Belgium (R.L.); Institute of Neuroscience and Psychology (K.W.M.) and Robertson Centre for Biostatistics (I.F.), University of Glasgow, United Kingdom; and Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria, Australia (V.T.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015233DOI Listing
March 2017

Prediction of Stroke Onset Is Improved by Relative Fluid-Attenuated Inversion Recovery and Perfusion Imaging Compared to the Visual Diffusion-Weighted Imaging/Fluid-Attenuated Inversion Recovery Mismatch.

Stroke 2016 10 6;47(10):2559-64. Epub 2016 Sep 6.

From the Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven-University of Leuven, B-3000 Leuven, Belgium (A.W., R. Lemmens); VIB, Vesalius Research Center, Laboratory of Neurobiology, B-3000 Leuven, Belgium (A.W., R. Lemmens); Department of Neurology, University Hospitals Leuven, B-3000 Leuven, Belgium (A.W., R. Lemmens); Laboratory for Cognitive Neurology, KU Leuven, Herestraat 49, 3000 Leuven, Belgium (P.D.); Department of Clinical Sciences, Section of Neurology, Lund University, Sweden (B.N.); Guided Development GmbH, Heidelberg, Germany (R. Laage); Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Neurologie, Kopf-und Neurozentrum, Hamburg, Germany (G.T.); Stroke Center, Stanford University, Palo Alto, CA (G.W.A.); and Department of Neurology Austin Health, and Melbourne Brain Center, Florey Institute of Neuroscience and Mental Health, Heidelberg, Australia (V.T.).

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http://dx.doi.org/10.1161/STROKEAHA.116.013903DOI Listing
October 2016

Detection of Atrial Fibrillation Among Patients With Stroke Due to Large or Small Vessel Disease: A Meta-Analysis.

J Am Heart Assoc 2016 Sep 26;5(9). Epub 2016 Sep 26.

KU Leuven-University of Leuven, Department of Neurosciences Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium VIB, Vesalius Research Center Laboratory of Neurobiology, Leuven, Belgium University Hospitals Leuven, Department of Neurology, Leuven, Belgium

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http://dx.doi.org/10.1161/JAHA.116.004151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079054PMC
September 2016

Genetic ablation of IP3 receptor 2 increases cytokines and decreases survival of SOD1G93A mice.

Hum Mol Genet 2016 08 4;25(16):3491-3499. Epub 2016 Jul 4.

KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND)

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http://dx.doi.org/10.1093/hmg/ddw190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179944PMC
August 2016

Association Between Time From Stroke Onset and Fluid-Attenuated Inversion Recovery Lesion Intensity Is Modified by Status of Collateral Circulation.

Stroke 2016 Apr 25;47(4):1018-22. Epub 2016 Feb 25.

From the Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven-University of Leuven, Leuven, Belgium (A.W., R.L.); Laboratory of Neurobiology, VIB, Vesalius Research Center, Leuven, Belgium (A.W., R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (A.W., R.L.); Laboratory for Cognitive Neurology, KU Leuven, Leuven, Belgium (P.D.); Department of Neurology, Stroke Center, Stanford University, Palo Alto, CA (S.C., G.A.); Section of Neurology, Department of Clinical Sciences, Lund University, Lund, Sweden (B.N.); Guided Development GmbH, Heidelberg, Germany (R.L.); Uinversitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Neurologie, Kopf-und Neurozentrum, Hamburg, Germany (G.T.); and Department of Neurology Austin Health, Melbourne Brain Center, Florey Institute of Neuroscience and Mental Health, Heidelberg, Australia (V.T.).

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http://dx.doi.org/10.1161/STROKEAHA.115.012010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811703PMC
April 2016

Aphasia 1 Week After Carotid Endarterectomy: Hypoperfusion or Hyperperfusion?

Stroke 2016 Apr 8;47(4):e63-5. Epub 2016 Mar 8.

From the Departments of Neurology (K.S., R.L.) and Radiology (P.D.), University Hospitals Leuven, Leuven, Belgium; Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, University of Leuven, Leuven, Belgium (R.L.); and Laboratory of Neurobiology, VIB, Vesalius Research Center, Leuven, Belgium (R.L.).

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http://dx.doi.org/10.1161/STROKEAHA.115.012263DOI Listing
April 2016

Non-infective endocarditis with systemic embolization and recurrent stroke in systemic sclerosis.

Rheumatology (Oxford) 2016 Mar 6;55(3):589-91. Epub 2015 Nov 6.

Department of Neurology and Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease, KU Leuven and VIB, Vesalius Research Center, Laboratory of Neurobiology, Leuven, Belgium

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http://dx.doi.org/10.1093/rheumatology/kev381DOI Listing
March 2016

Enhanced phasic GABA inhibition during the repair phase of stroke: a novel therapeutic target.

Brain 2016 Feb 18;139(Pt 2):468-80. Epub 2015 Dec 18.

1 Department of Neurosurgery, Stanford University, Stanford, CA, USA 2 Stanford Stroke Centre, Palo Alto, CA 94304, USA 3 Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA

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http://dx.doi.org/10.1093/brain/awv360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805083PMC
February 2016

Effect of endovascular reperfusion in relation to site of arterial occlusion.

Neurology 2016 Feb 22;86(8):762-70. Epub 2016 Jan 22.

From KU Leuven, University of Leuven, Belgium, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (R.L.); University Hospitals Leuven, Department of Neurology (R.L.); VIB, Vesalius Research Center, Laboratory of Neurobiology (R.L.); Stanford Stroke Center (S.A.H., M.P.M., G.W.A., M.G.L.), Stanford University of Medicine, CA; Neurovascular Imaging Research Core and Department of Neurology and Comprehensive Stroke Center (D.S.L., J.L.S.), and Division of Interventional Neuroradiology, Department of Radiology, David Geffen School of Medicine (R.J.), University of California, Los Angeles; Departments of Radiology (T.A.T.) and Neurology (J.P.B.), University of Cincinnati Medical Center, OH; Departments of Clinical Neurosciences and Radiology (A.M.D.), Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Canada; Departments of Neurology, Neurosurgery, and Radiology (R.G.N.), Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA; Department of Diagnostic and Interventional Neuroradiology (J.G.), University Hospital Bern, Switzerland; Division of Diagnostic and Interventional Neuroradiology (A.J.Y.), Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston; Department of Public Health Sciences (S.D.Y., Y.Y.P.), Medical University of South Carolina, Charleston; and Division of Neuroradiology, Department of Medical Imaging, and Division of Neurosurgery, Department of Surgery (V.M.P.), Toronto Western Hospital, University Health Network, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000002399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763803PMC
February 2016

Magnetic resonance imaging-based endovascular versus medical stroke treatment for symptom onset up to 12 h.

Int J Stroke 2016 Jan;11(1):127-33

KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium VIB, Vesalius Research Center, Laboratory of Neurobiology, Leuven, Belgium University Hospitals Leuven, Department of Neurology, Leuven, Belgium.

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http://dx.doi.org/10.1177/1747493015607503DOI Listing
January 2016

Limb-shaking TIA during balloon test occlusion of the internal carotid artery.

Acta Neurol Belg 2015 Sep 5;115(3):449-51. Epub 2014 Oct 5.

Department of Neurology, University Hospitals Leuven, University of Leuven and VIB, Herestraat 49, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1007/s13760-014-0366-zDOI Listing
September 2015

Recommendations from the international stroke genetics consortium, part 2: biological sample collection and storage.

Stroke 2015 Jan 9;46(1):285-90. Epub 2014 Dec 9.

From the Center for Human Genetic Research (T.W.K.B., V.V., S.B.K., C.K., C.D.A., G.J.F., J.R.), Division of Neurocritical Care and Emergency Neurology (T.W.K.B., C.K., C.D.A., G.J.F., J.R.), and Department of Neurology (F.J.M.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute, Cambridge (T.W.K.B., C.K., C.D.A., G.J.F., J.R.); School of Systems Biomedical Science, Soongsil University, Seoul, South Korea (C.L.); Department of Neurology, Institut Hospital del Mar d'Investigacions Mèdiques, Universitat Autonoma de Barcelona, Barcelona, Spain (J.J.-C.); Stroke Pharmacogenomics and Genetics Fundacio Docencia i Recerca MutuaTerrassa, Hospital Mutua de Terrassa, Terrassa, Spain (I.F.-C.); Department of Pathology and Molecular Medicine, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada (G.P.); Miller School of Medicine, University of Miami (T.R.); Departments of Anesthesiology and Neurology, Duke University, Durham (M.L.J.); Department of Neurosciences, VIB-Vesalius Research Center, Experimental Neurology-Laboratory of Neurobiology, KU Leuven, University of Leuven, Leuven, Belgium (R.L.); Department of Neurology, University Hospitals Leuven, Leuven, Belgium (R.L.); Department of Neurology, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan (T.-H.L.); Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (T.T.); Department of Neurology, Veterans Administration Medical Center and University of Maryland School of Medicine, Baltimore (S.J.K.); Department of Clinical Sciences, Neurology, Lund University and Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (A.L.); Department of Neurology, Brigham and Women's Hospital, Boston (A.L.B.); School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (E.G.H.); Hunter Medical Research Institute, Newcastle, New South Wales

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http://dx.doi.org/10.1161/STROKEAHA.114.006851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276505PMC
January 2015

Pathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network.

Stroke 2014 Dec 6;45(12):3589-96. Epub 2014 Nov 6.

From the Department of Radiology, AA Martinos Center for Biomedical Imaging (H.A., E.M.A., T.B.), Stroke Service, Department of Neurology (H.A., J.R.), and Center for Human Genetic Research (J.R.), Massachusetts General Hospital, Harvard Medical School, Boston; Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (G.A., H.D., A.L., O.M., B.N.); Department of Neurology, Mayo Clinic Rochester, MN (R.D.B.); Department of Neurology (S.N.C., B.B.W.), Center for Public Health Genomics (S.S.R.), and Department of Public Health Sciences (B.B.W.), University of Virginia, Charlottesville; Department of Neurology (J.W.C., S.J.K.) and Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine (P.F.M.), University of Maryland School of Medicine, Baltimore; Institute for Stroke and Dementia Research (ISD), Klinikum der Universität München, Ludwig-Maximilians-University, München, Germany (M.D., M.L.); Department of Clinical Science, Lund University, Malmö, Sweden (G.E., B.N.); Department of Neurology, Neurovascular Research Group, IMIM-Hospital del Mar, Universitat Autonoma de Barcelona/DCEXS-Universitat Pompeu Fabra, Spain (E.G.-S., J.J.-C., J.R.); Neuroscience Institute, Saint Francis Medical Center, Trenton, NJ (R.P.G., L.R.P.); National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (K.G.); Institute of Biomedicine (C.J., A.P.) and Institute of Neuroscience and Physiology (K.J.), Sahlgrenska Academy at University of Gothenburg, Sweden; Department of Neurology, University of Miami Miller School of Medicine, FL (M.K., T.R., R.L.S.); Department of Neurology, University of Cincinnati College of Medicine, OH (B.K., D.O.K.); Department of Neurology, Stern Stroke Center, Albert Einstein College of Medicine, Bronx, NY (D.L.L.); Department of Neuroscience and Sensory Organs, Policlinico Hospital Foundation IRCCS Cà Granda, Milan, Italy (S.L.); Department of Neurology, Washington U

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http://dx.doi.org/10.1161/STROKEAHA.114.007362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286169PMC
December 2014

Wake-up stroke and stroke of unknown onset: a critical review.

Front Neurol 2014 12;5:153. Epub 2014 Aug 12.

KU Leuven Department of Neurosciences and Experimental Neurology, KU Leuven , Leuven , Belgium ; Department of Neurology, University Hospital Leuven , Leuven , Belgium ; Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven , Leuven , Belgium ; Laboratory of Neurobiology, Vesalius Research Center , Leuven , Belgium.

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http://dx.doi.org/10.3389/fneur.2014.00153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129498PMC
August 2014

Genetic ablation of phospholipase C delta 1 increases survival in SOD1(G93A) mice.

Neurobiol Dis 2013 Dec 19;60:11-7. Epub 2013 Aug 19.

Laboratory of Neurobiology, Belgium; Leuven Research Institute of Neuroscience and Disease (LIND), KU Leuven, Belgium; Vesalius Research Center, VIB, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2013.08.006DOI Listing
December 2013

Stem cell therapy for acute cerebral injury: what do we know and what will the future bring?

Curr Opin Neurol 2013 Dec;26(6):617-25

aLaboratory of Neurobiology, Vesalius Research Center, VIB bExperimental Neurology and Leuven Research Institute for Neurodegenerative Diseases (LIND), University of Leuven cDepartment of Neurology, University Hospitals Leuven, Leuven, Belgium dDepartment of Neurosurgery, Stanford Stroke Center, and Stanford Institute for Neuro-Innovation & Translational Neurosciences, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1097/WCO.0000000000000023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465754PMC
December 2013

Modifying expression of EphA4 and its downstream targets improves functional recovery after stroke.

Hum Mol Genet 2013 Jun 14;22(11):2214-20. Epub 2013 Feb 14.

Laboratory of Neurobiology, Vesalius Research Center, VIB, Leuven, Belgium.

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http://dx.doi.org/10.1093/hmg/ddt073DOI Listing
June 2013

Clinical scores for predicting recurrence after transient ischemic attack or stroke: how good are they?

Stroke 2013 Apr 12;44(4):1198-203. Epub 2013 Mar 12.

Laboratory of Neurobiology, Vesalius Research Center, VIB, Leuven, Belgium.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.111.000141
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April 2013

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.

Lancet Neurol 2012 Nov 5;11(11):951-62. Epub 2012 Oct 5.

Stroke and Dementia Research Centre, St George's University of London, London, UK.

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http://dx.doi.org/10.1016/S1474-4422(12)70234-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490334PMC
November 2012

Transient hemiparesis caused by spontaneous cervical epidural hematoma.

Acta Neurol Belg 2012 Sep 8;112(3):291-3. Epub 2012 May 8.

Laboratory for Neurobiology, Experimental Neurology, KU Leuven, and Vesalius Research Center, VIB, Leuven, Belgium.

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http://dx.doi.org/10.1007/s13760-012-0079-0DOI Listing
September 2012

Postpartum RCVS and PRES with normal initial imaging findings.

Acta Neurol Belg 2012 Jun 9;112(2):189-92. Epub 2012 Mar 9.

Laboratory for Neurobiology, Experimental Neurology, KU Leuven, and Vesalius Research Center, VIB, Leuven, Belgium.

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http://dx.doi.org/10.1007/s13760-012-0051-zDOI Listing
June 2012

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.

Nat Genet 2012 Feb 5;44(3):328-33. Epub 2012 Feb 5.

Wellcome Trust Centre for Human Genetics, University of Oxford, UK.

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http://www.nature.com/articles/ng.1081
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http://dx.doi.org/10.1038/ng.1081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303115PMC
February 2012

Genetics of atrial fibrillation and possible implications for ischemic stroke.

Stroke Res Treat 2011 27;2011:208694. Epub 2011 Jul 27.

Department of Neurology and Laboratory for Neurobiology, Section of Experimental Neurology, School of Medicine, University of Leuven, Herestraat 49, 3000 Leuven, Belgium.

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http://dx.doi.org/10.4061/2011/208694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148589PMC
November 2011

Unilateral white matter involvement in Krabbe disease.

Arch Neurol 2011 Jan;68(1):130-1

Department of Neurology, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1001/archneurol.2010.331DOI Listing
January 2011

Microbleeds and the risk of recurrent stroke.

Stroke 2010 Sep 22;41(9):2005-9. Epub 2010 Jul 22.

Department of Neurology, Vesalius Research Center, University Hospitals, Herestraat 49, B3000 Leuven, Belgium.

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http://dx.doi.org/10.1161/STROKEAHA.110.588020DOI Listing
September 2010

RNA metabolism and the pathogenesis of motor neuron diseases.

Trends Neurosci 2010 May 11;33(5):249-58. Epub 2010 Mar 11.

Department of Neurology (University Hospitals Leuven) and Laboratory for Neurobiology, Section of Experimental Neurology, School of Medicine, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1016/j.tins.2010.02.003DOI Listing
May 2010

Is there a decline in the vascular event rate after transient ischemic attack or stroke in antiplatelet trials?

Cerebrovasc Dis 2009 8;28(5):439-47. Epub 2009 Sep 8.

Department of Neurology, University Hospitals Leuven, Belgium.

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https://www.karger.com/Article/FullText/235988
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January 2010