Robin Allshire

: A fast and efficient CRISPR/Cas9 method for fission yeast.

Authors:

Sito Torres-Garcia Lorenza Di Pompeo Luke Eivers Baptiste Gaborieau Sharon A White Alison L Pidoux Paulina Kanigowska Imtiyaz Yaseen Yizhi Cai Robin C Allshire

Wellcome Open Res 2020 24;5:274. Epub 2020 Nov 24.

Wellcome Centre for Cell Biology and Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Mayfield Road, Edinburgh, EH9 3BF, UK.

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November 2020

Large domains of heterochromatin direct the formation of short mitotic chromosome loops.

Authors:

Maximilian H Fitz-James Pin Tong Alison L Pidoux Hakan Ozadam Liyan Yang Sharon A White Job Dekker Robin C Allshire

Elife 2020 09 11;9. Epub 2020 Sep 11.

Wellcome Centre for Cell Biology and Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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September 2020

Epigenetic gene silencing by heterochromatin primes fungal resistance.

Authors:

Sito Torres-Garcia Imtiyaz Yaseen Manu Shukla Pauline N C B Audergon Sharon A White Alison L Pidoux Robin C Allshire

Nature 2020 09 9;585(7825):453-458. Epub 2020 Sep 9.

Wellcome Centre for Cell Biology, Institute of Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.

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September 2020

TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing.

Authors:

Theresa Schöpp Ansgar Zoch Rebecca V Berrens Tania Auchynnikava Yuka Kabayama Lina Vasiliauskaitė Juri Rappsilber Robin C Allshire Dónal O'Carroll

Nat Commun 2020 07 27;11(1):3739. Epub 2020 Jul 27.

Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK.

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July 2020

SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation.

Authors:

Ansgar Zoch Tania Auchynnikava Rebecca V Berrens Yuka Kabayama Theresa Schöpp Madeleine Heep Lina Vasiliauskaitė Yuvia A Pérez-Rico Atlanta G Cook Alena Shkumatava Juri Rappsilber Robin C Allshire Dónal O'Carroll

Nature 2020 08 16;584(7822):635-639. Epub 2020 Jul 16.

Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.

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August 2020

Hap2-Ino80-facilitated transcription promotes de novo establishment of CENP-A chromatin.

Authors:

Puneet P Singh Manu Shukla Sharon A White Marcel Lafos Pin Tong Tatsiana Auchynnikava Christos Spanos Juri Rappsilber Alison L Pidoux Robin C Allshire

Genes Dev 2020 02 9;34(3-4):226-238. Epub 2020 Jan 9.

Wellcome Centre for Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh EH9 3BF, United Kingdom.

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February 2020

Interspecies conservation of organisation and function between nonhomologous regional centromeres.

Authors:

Pin Tong Alison L Pidoux Nicholas R T Toda Ryan Ard Harald Berger Manu Shukla Jesus Torres-Garcia Carolin A Müller Conrad A Nieduszynski Robin C Allshire

Nat Commun 2019 05 28;10(1):2343. Epub 2019 May 28.

Wellcome Centre for Cell Biology and Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Mayfield Road, Edinburgh, EH9 3BF, UK.

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May 2019

Fitness Landscape of the Fission Yeast Genome.

Authors:

Leanne Grech Daniel C Jeffares Christoph Y Sadée María Rodríguez-López Danny A Bitton Mimoza Hoti Carolina Biagosch Dimitra Aravani Maarten Speekenbrink Christopher J R Illingworth Philipp H Schiffer Alison L Pidoux Pin Tong Victor A Tallada Robin Allshire Henry L Levin Jürg Bähler

Mol Biol Evol 2019 08;36(8):1612-1623

Department of Genetics, Evolution and Environment, University College London, London, United Kingdom.

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August 2019

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis.

Authors:

Marcos Morgan Yuka Kabayama Christian Much Ivayla Ivanova Monica Di Giacomo Tatsiana Auchynnikava Jack Michael Monahan Dimitrios Michael Vitsios Lina Vasiliauskaitė Stefano Comazzetto Juri Rappsilber Robin Campbell Allshire Bo Torben Porse Anton James Enright Dónal O'Carroll

Cell Res 2019 03 7;29(3):221-232. Epub 2019 Jan 7.

MRC Centre for Regenerative Medicine, School of Biological Sciences, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK.

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March 2019

Centromere DNA Destabilizes H3 Nucleosomes to Promote CENP-A Deposition during the Cell Cycle.

Authors:

Manu Shukla Pin Tong Sharon A White Puneet P Singh Angus M Reid Sandra Catania Alison L Pidoux Robin C Allshire

Curr Biol 2018 12 29;28(24):3924-3936.e4. Epub 2018 Nov 29.

Wellcome Centre for Cell Biology and Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh EH9 3BF, UK. Electronic address:

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December 2018

Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions.

Nat Genet 2019 01 26;51(1):96-105. Epub 2018 Nov 26.

MRC Human Genetics Unit, IGMM, University of Edinburgh, Edinburgh, UK.

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January 2019

Ten principles of heterochromatin formation and function.

Authors:

Robin C Allshire Hiten D Madhani

Nat Rev Mol Cell Biol 2018 04 13;19(4):229-244. Epub 2017 Dec 13.

Chan-Zuckerberg BioHub, San Francisco, California 94158, USA.

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April 2018

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit.

Authors:

Laura Milligan Camille Sayou Alex Tuck Tatsiana Auchynnikava Jane Ea Reid Ross Alexander Flavia de Lima Alves Robin Allshire Christos Spanos Juri Rappsilber Jean D Beggs Grzegorz Kudla David Tollervey

Elife 2017 10 13;6. Epub 2017 Oct 13.

Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, Scotland.

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October 2017

Emerging Properties and Functional Consequences of Noncoding Transcription.

Authors:

Ryan Ard Robin C Allshire Sebastian Marquardt

Genetics 2017 10;207(2):357-367

Copenhagen Plant Science Centre, Department of Plant and Environmental Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark

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October 2017

Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in .

Authors:

Rajesh K Yadav Carolyn M Jablonowski Alfonso G Fernandez Brandon R Lowe Ryan A Henry David Finkelstein Kevin J Barnum Alison L Pidoux Yin-Ming Kuo Jie Huang Matthew J O'Connell Andrew J Andrews Arzu Onar-Thomas Robin C Allshire Janet F Partridge

Elife 2017 07 18;6. Epub 2017 Jul 18.

Department of Pathology, St. Jude Children's Research Hospital, Memphis, United States.

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July 2017

Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution.

Authors:

Matthew P Davis Claudia Carrieri Harpreet K Saini Stijn van Dongen Tommaso Leonardi Giovanni Bussotti Jack M Monahan Tania Auchynnikava Angelo Bitetti Juri Rappsilber Robin C Allshire Alena Shkumatava Dónal O'Carroll Anton J Enright

EMBO Rep 2017 07 12;18(7):1231-1247. Epub 2017 May 12.

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK

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July 2017

Transcription-coupled changes to chromatin underpin gene silencing by transcriptional interference.

Authors:

Ryan Ard Robin C Allshire

Nucleic Acids Res 2016 12 8;44(22):10619-10630. Epub 2016 Sep 8.

Wellcome Trust Centre for Cell Biology and Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh EH9 3BF, Scotland, UK

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December 2016