Roberto Pola

Roberto Pola

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Roberto Pola

Roberto Pola

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Differences in Clinical Presentation, Rate of Pulmonary Embolism, and Risk Factors Among Patients With Deep Vein Thrombosis in Unusual Sites.

Clin Appl Thromb Hemost 2019 Jan-Dec;25:1076029619872550

Department of Medicine, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1177/1076029619872550DOI Listing
September 2019

Antithrombotic therapy and intracranial bleeding in subjects with sporadic brain arteriovenous malformations: preliminary results from a retrospective study.

Intern Emerg Med 2018 Dec 30;13(8):1227-1232. Epub 2018 Jul 30.

Institute of Medicine, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

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http://dx.doi.org/10.1007/s11739-018-1918-7DOI Listing
December 2018

Microparticles Carrying Sonic Hedgehog Are Increased in Humans with Peripheral Artery Disease.

Int J Mol Sci 2018 Dec 9;19(12). Epub 2018 Dec 9.

Department of Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.

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http://dx.doi.org/10.3390/ijms19123954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320804PMC
December 2018

Sonic Hedgehog Signaling Pathway in Endothelial Progenitor Cell Biology for Vascular Medicine.

Int J Mol Sci 2018 Oct 5;19(10). Epub 2018 Oct 5.

Department of Regenerative Medicine Science, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 2591193, Japan.

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http://dx.doi.org/10.3390/ijms19103040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213474PMC
October 2018

Microparticles Produced by Activated Platelets Carry a Potent and Functionally Active Angiogenic Signal in Subjects with Crohn's Disease.

Int J Mol Sci 2018 Sep 26;19(10). Epub 2018 Sep 26.

Division of Vascular Medicine, Department of Medicine, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.

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http://dx.doi.org/10.3390/ijms19102921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212893PMC
September 2018

Diagnostic and prognostic role of circulating microparticles in hepatocellular carcinoma.

J Hepatol 2017 Sep 21. Epub 2017 Sep 21.

Internal Medicine, Gastroenterology and Hepatology, Agostino Gemelli Hospital, Rome, Italy.

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http://dx.doi.org/10.1016/j.jhep.2017.07.035DOI Listing
September 2017

Genome-wide association study of sporadic brain arteriovenous malformations.

J Neurol Neurosurg Psychiatry 2016 09 27;87(9):916-23. Epub 2016 Jan 27.

Department of Anesthesia and Perioperative Care, Center for Cerebrovascular Research, University of California, San Francisco, California, USA Department of Epidemiology and Biostatistics, University of California, San Francisco, California, USA Institute for Human Genetics, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1136/jnnp-2015-312272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963303PMC
September 2016

Controversies in venous thromboembolism: the unique case of isolated distal deep vein thrombosis.

Intern Emerg Med 2016 Sep 28;11(6):775-9. Epub 2016 Apr 28.

Division of Internal Medicine and Vascular Diseases, Department of Medicine, A. Gemelli University Hospital, Catholic University School of Medicine, Largo Agostino Gemelli 8, 00168, Rome, Italy.

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http://dx.doi.org/10.1007/s11739-016-1453-3DOI Listing
September 2016

Thromboprophylaxis in patients with stroke: a delicate decision.

Eur J Intern Med 2014 Oct 17;25(8):e93-4. Epub 2014 Jul 17.

Department of Medicine, "Agostino Gemelli" University Hospital, Catholic University School of Medicine 1, Largo A. Gemelli, 00168 Rome, Italy.

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http://dx.doi.org/10.1016/j.ejim.2014.07.001DOI Listing
October 2014

Sonic hedgehog therapy in a mouse model of age-associated impairment of skeletal muscle regeneration.

J Gerontol A Biol Sci Med Sci 2014 Mar 18;69(3):245-52. Epub 2013 Jun 18.

Center of Cancer Systems Biology, CBR4, St. Elizabeth's Medical Center, Tufts University School of Medicine, 736 Cambridge Street, Boston, MA 02135.

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http://dx.doi.org/10.1093/gerona/glt076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976139PMC
March 2014

Angiogenic impairment of the vascular endothelium: a novel mechanism and potential therapeutic target in muscular dystrophy.

Arterioscler Thromb Vasc Biol 2013 Dec 26;33(12):2867-76. Epub 2013 Sep 26.

From the Division of Cardiovascular Research, Department of Medicine (M.P., V.N., R.C.S., M.S., R.P.), and Center of Cancer Systems Biology (R.C.S., L.H., R.P.), St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA; Laboratory of Vascular Biology and Genetics and Department of Medicine, A. Gemelli University Hospital, Catholic University School of Medicine, Rome, Italy (M.P., I.G., V.N., E.G., M.M., I.G., E.S., R.L., R.P.); and Laboratory of Vascular Pathology, IDI Research Institute, Rome, Italy (S.S., M.C.).

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http://dx.doi.org/10.1161/ATVBAHA.112.301172DOI Listing
December 2013

V1-V2-V3-V4 T wave inversion: left or right ventricle?

BMJ Case Rep 2013 Oct 9;2013. Epub 2013 Oct 9.

Department of Internal Medicine, Catholic University of Rome, Roma, Italy.

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http://dx.doi.org/10.1136/bcr-2013-200331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822171PMC
October 2013

Association between the rs1333040 polymorphism on the chromosomal 9p21 locus and sporadic brain arteriovenous malformations.

J Neurol Neurosurg Psychiatry 2013 Sep 19;84(9):1059-62. Epub 2013 Apr 19.

Department of Neurosurgery, Catholic University School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1136/jnnp-2012-304045DOI Listing
September 2013

Single nucleotide polymorphisms associated with sporadic brain arteriovenous malformations: where do we stand?

Brain 2013 Feb 13;136(Pt 2):665-81. Epub 2012 Sep 13.

Department of Neurosurgery, Catholic University School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1093/brain/aws180DOI Listing
February 2013

Combined therapy with sonic hedgehog gene transfer and bone marrow-derived endothelial progenitor cells enhances angiogenesis and myogenesis in the ischemic skeletal muscle.

J Vasc Res 2012 22;49(5):425-31. Epub 2012 Jun 22.

Laboratory of Vascular Biology and Genetics, Department of Medicine, A. Gemelli University Hospital, Catholic University School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1159/000337921DOI Listing
October 2012

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.

J Am Coll Cardiol 2012 Aug;60(8):722-9

Population Genomics, deCODE Genetics, Reykjavik, Iceland.

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http://dx.doi.org/10.1016/j.jacc.2012.01.078DOI Listing
August 2012

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.

Authors:
Solveig Gretarsdottir Annette F Baas Gudmar Thorleifsson Hilma Holm Martin den Heijer Jean-Paul P M de Vries Steef E Kranendonk Clark J A M Zeebregts Steven M van Sterkenburg Robert H Geelkerken Andre M van Rij Michael J A Williams Albert P M Boll Jelena P Kostic Adalbjorg Jonasdottir Aslaug Jonasdottir G Bragi Walters Gisli Masson Patrick Sulem Jona Saemundsdottir Magali Mouy Kristinn P Magnusson Gerard Tromp James R Elmore Natzi Sakalihasan Raymond Limet Jean-Olivier Defraigne Robert E Ferrell Antti Ronkainen Ynte M Ruigrok Cisca Wijmenga Diederick E Grobbee Svati H Shah Christopher B Granger Arshed A Quyyumi Viola Vaccarino Riyaz S Patel A Maziar Zafari Allan I Levey Harland Austin Domenico Girelli Pier Franco Pignatti Oliviero Olivieri Nicola Martinelli Giovanni Malerba Elisabetta Trabetti Lewis C Becker Diane M Becker Muredach P Reilly Daniel J Rader Thomas Mueller Benjamin Dieplinger Meinhard Haltmayer Sigitas Urbonavicius Bengt Lindblad Anders Gottsäter Eleonora Gaetani Roberto Pola Philip Wells Marc Rodger Melissa Forgie Nicole Langlois Javier Corral Vicente Vicente Jordi Fontcuberta Francisco España Niels Grarup Torben Jørgensen Daniel R Witte Torben Hansen Oluf Pedersen Katja K Aben Jacqueline de Graaf Suzanne Holewijn Lasse Folkersen Anders Franco-Cereceda Per Eriksson David A Collier Hreinn Stefansson Valgerdur Steinthorsdottir Thorunn Rafnar Einar M Valdimarsson Hulda B Magnadottir Sigurlaug Sveinbjornsdottir Isleifur Olafsson Magnus Karl Magnusson Robert Palmason Vilhelmina Haraldsdottir Karl Andersen Pall T Onundarson Gudmundur Thorgeirsson Lambertus A Kiemeney Janet T Powell David J Carey Helena Kuivaniemi Jes S Lindholt Gregory T Jones Augustine Kong Jan D Blankensteijn Stefan E Matthiasson Unnur Thorsteinsdottir Kari Stefansson

Nat Genet 2010 Aug 11;42(8):692-7. Epub 2010 Jul 11.

Population Genomics, deCODE Genetics, Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157066PMC
August 2010

Influence of growth hormone receptor d3 and full-length isoforms on biochemical treatment outcomes in acromegaly.

J Clin Endocrinol Metab 2009 Jun 31;94(6):2015-22. Epub 2009 Mar 31.

Division of Endocrinology, Catholic University, School of Medicine, Largo A. Gemelli, 8, Rome 00168, Italy.

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http://dx.doi.org/10.1210/jc.2008-1337DOI Listing
June 2009

Inflammatory markers for ischaemic stroke.

Authors:
Roberto Pola

Thromb Haemost 2009 May;101(5):800-1

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May 2009

Frequency-modulated electromagnetic neural stimulation enhances cutaneous microvascular flow in patients with diabetic neuropathy.

J Diabetes Complications 2009 Jan-Feb;23(1):46-8. Epub 2008 Apr 10.

Department of Medicine, Diabetes and Endocrinology Unit, San Raffaele Scientific Institute and Vita-Salute San Raffaele University, Via Olgettina, 60, 20132 Milan, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S105687270800026
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http://dx.doi.org/10.1016/j.jdiacomp.2008.02.004DOI Listing
February 2009

Selective activation of peroxisome proliferator-activated receptor (PPAR)alpha and PPAR gamma induces neoangiogenesis through a vascular endothelial growth factor-dependent mechanism.

Diabetes 2008 May 11;57(5):1394-404. Epub 2008 Feb 11.

Laboratory of Vascular Biology and Genetics, Department of Medicine, A. Gemelli University Hospital, Catholic University School of Medicine, Rome, Italy.

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http://dx.doi.org/10.2337/db07-0765DOI Listing
May 2008

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm.

Nat Genet 2008 Feb 6;40(2):217-24. Epub 2008 Jan 6.

deCODE Genetics, Sturlugata 8, IS-101 Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.72DOI Listing
February 2008

Analysis of functional polymorphisms of metalloproteinase genes in persons with vascular dementia and Alzheimer's disease.

J Gerontol A Biol Sci Med Sci 2006 Oct;61(10):1065-9

Istituto di Medicina Interna e Geriatria, Policlinico A. Gemelli, Università Cattolica del Sacro Cuore, L.go A. Gemelli 8, 00168 Rome, Italy.

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http://dx.doi.org/10.1093/gerona/61.10.1065DOI Listing
October 2006

Angiogenesis as a novel component of inflammatory bowel disease pathogenesis.

Gastroenterology 2006 Jun;130(7):2060-73

Division of Gastroenterology, Istituto Clinico Humanitas, IRCCS in Gastroenterology, Rozzano, Milan, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S001650850600739
Publisher Site
http://dx.doi.org/10.1053/j.gastro.2006.03.054DOI Listing
June 2006

Hydatid cyst of the spine.

Lancet Infect Dis 2005 Nov;5(11):732

Department of Orthopaedics and Spinal Surgery, A Gemelli University Hospital, Catholic University School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1016/S1473-3099(05)70272-3DOI Listing
November 2005

Responsiveness to cholinesterase inhibitors in Alzheimer's disease: a possible role for the 192 Q/R polymorphism of the PON-1 gene.

Neurosci Lett 2005 Jul 7;382(3):338-41. Epub 2005 Apr 7.

Laboratory of Vascular Biology and Genetics, Department of Medicine, A. Gemelli University Hospital, Catholic University School of Medicine, L.go A. Gemelli 8, 00168 Rome, Italy.

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http://dx.doi.org/10.1016/j.neulet.2005.03.027DOI Listing
July 2005

Homocysteine triggers mucosal microvascular activation in inflammatory bowel disease.

Am J Gastroenterol 2005 Apr;100(4):886-95

Department of Internal Medicine, Institute of General Pathology, Catholic University, Rome, Italy.

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http://dx.doi.org/10.1111/j.1572-0241.2005.41469.xDOI Listing
April 2005

Polymorphisms of the macrophage inhibitory factor and C-reactive protein genes in subjects with Alzheimer's dementia.

Dement Geriatr Cogn Disord 2004 29;18(3-4):261-4. Epub 2004 Jul 29.

Laboratory of Vascular Biology and Genetics, Department of Medicine, A. Gemelli University Hospital, Università Cattolica del Sacro Cuore School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1159/000080026DOI Listing
February 2005

Hyperhomocyst(e)inemia impairs angiogenesis in a murine model of limb ischemia.

Vasc Med 2005 Feb;10(1):15-22

Department of Medicine (Cardiovascular Research), Caritas St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA 02135-2997, USA.

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http://dx.doi.org/10.1191/1358863x05vm585oaDOI Listing
February 2005

Age-dependent VEGF expression and intraneural neovascularization during regeneration of peripheral nerves.

Neurobiol Aging 2004 Nov-Dec;25(10):1361-8

Department of Medicine (Cardiovascular Research), St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2004.02.028DOI Listing
December 2004

Sonic hedgehog induces arteriogenesis in diabetic vasa nervorum and restores function in diabetic neuropathy.

Arterioscler Thromb Vasc Biol 2004 Nov 9;24(11):2102-7. Epub 2004 Sep 9.

Division of Cardiovascular Research, St. Elizabeth Medical Center Boston, Boston, MA 02135, USA.

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http://dx.doi.org/10.1161/01.ATV.0000144813.44650.75DOI Listing
November 2004

Proinflammatory genetic profiles in subjects with history of ischemic stroke.

Stroke 2004 Oct 12;35(10):2270-5. Epub 2004 Aug 12.

Laboratory of Vascular Biology and Genetics, . Gemelli University Hospital, Università Cattolica del Sacro Cuore, School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1161/01.STR.0000140740.19421.feDOI Listing
October 2004

Treatment of ischemic ulcers of the lower limbs with alprostadil (prostaglandin E1).

Dermatol Surg 2004 Aug;30(8):1113-7

Department of Internal Medicine, A. Gemelli University Hospital, Catholic University of Sacred Heart, Rome, Italy.

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http://dx.doi.org/10.1111/j.1524-4725.2004.30336.xDOI Listing
August 2004

Monocyte chemoattractant protein-1 (MCP-1) gene polymorphism and risk of Alzheimer's disease in Italians.

Exp Gerontol 2004 Aug;39(8):1249-52

Laboratory of Vascular Biology and Genetics, Department of Medicine, A. Gemelli University Hospital, Università Cattolica del Sacro Cuore School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1016/j.exger.2004.05.001DOI Listing
August 2004

Age-dependent modifications of expression level of VEGF and its receptors in the inner ear.

Exp Gerontol 2004 Aug;39(8):1253-8

Institute of Otolaryngology, A. Gemelli University Hospital, Università Cattolica del Sacro Cuore School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1016/j.exger.2004.06.003DOI Listing
August 2004

Association between altered circadian blood pressure profile and cardiac end-organ damage in patients with renovascular hypertension.

Cardiology 2003 ;100(3):114-9

Istituto di Patologia Speciale Medica e Semeiotica Medica, Università Cattolica del Sacro Cuore, Rome, Italy.

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http://dx.doi.org/10.1159/000073911DOI Listing
March 2004

Peripheral nerve ischemia: apolipoprotein E deficiency results in impaired functional recovery and reduction of associated intraneural angiogenic response.

Exp Neurol 2003 Nov;184(1):264-73

Laboratory of Vascular Biology and Genetics, A. Gemelli University Hospital, Università Cattolica del Sacro Cuore School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1016/s0014-4886(03)00260-7DOI Listing
November 2003

Postnatal recapitulation of embryonic hedgehog pathway in response to skeletal muscle ischemia.

Circulation 2003 Jul 14;108(4):479-85. Epub 2003 Jul 14.

Department of Medicine (Cardiovascular Research), St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Mass 02135-2997, USA.

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http://dx.doi.org/10.1161/01.CIR.0000080338.60981.FADOI Listing
July 2003

Synergistic effect of -174 G/C polymorphism of the interleukin-6 gene promoter and 469 E/K polymorphism of the intercellular adhesion molecule-1 gene in Italian patients with history of ischemic stroke.

Stroke 2003 Apr 13;34(4):881-5. Epub 2003 Mar 13.

Laboratory of Vascular Biology and Genetics, Department of Geriatric Medicine, A. Gemelli University Hospital, Università Cattolica del Sacro Cuore School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1161/01.STR.0000062346.70983.DFDOI Listing
April 2003

Intercellular adhesion molecule-1 K469E gene polymorphism and Alzheimer's disease.

Neurobiol Aging 2003 Mar-Apr;24(2):385-7

Laboratory of Vascular Biology and Genetics, Istituto di Patologia Speciale Medica, Università Cattolica del Sacro Cuore, A. Gemelli University Hospital, L. go A. Gemelli 8, 00168 Rome, Italy.

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http://dx.doi.org/10.1016/s0197-4580(02)00087-8DOI Listing
March 2003

Lack of association between Alzheimer's disease and Gln-Arg 192 Q/R polymorphism of the PON-1 gene in an Italian population.

Dement Geriatr Cogn Disord 2003 ;15(2):88-91

Laboratory of Vascular Biology and Genetics, A. Gemelli University Hospital, Università Cattolica del Sacro Cuore School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1159/000067975DOI Listing
March 2003

Angiotensin-converting enzyme gene polymorphism may influence blood loss in a geriatric population undergoing total hip arthroplasty.

J Am Geriatr Soc 2002 Dec;50(12):2025-8

Department of Orthopedics, A. Gemelli University Hospital, Università Cattolica del Sacro Cuore, School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1046/j.1532-5415.2002.50616.xDOI Listing
December 2002

The -174 G/C polymorphism of the interleukin-6 gene promoter is associated with Alzheimer's disease in an Italian population [corrected].

Neuroreport 2002 Sep;13(13):1645-7

Laboratory of Vascular Biology and Genetics, A Gemelli University Hospital, Università Cattolica del Sacro Cuore School of Medicine, L.go A. Gemelli 8, 00168 Rome, Italy.

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http://dx.doi.org/10.1097/00001756-200209160-00015DOI Listing
September 2002

-174 G/C interleukin-6 gene polymorphism and increased risk of multi-infarct dementia: a case-control study.

Exp Gerontol 2002 Jul;37(7):949-55

Laboratory of Vascular Biology and Genetics A. Gemelli University Hospital, Università Cattolica del Sacro Cuore School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1016/s0531-5565(02)00031-1DOI Listing
July 2002

Association between intercellular adhesion molecule-1 E/K gene polymorphism and probable vascular dementia in humans.

Neurosci Lett 2002 Jul;326(3):171-4

Laboratory of Vascular Biology and Genetics, A. Gemelli University Hospital, Università Cattolica del Sacro Cuore School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1016/s0304-3940(02)00337-3DOI Listing
July 2002

Tumoral calcinosis.

Lancet 2002 May;359(9320):1818

Department of Orthopedics, School of Medicine, Rome, Italy.

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http://dx.doi.org/10.1016/s0140-6736(02)08712-3DOI Listing
May 2002