Roberto Giacomelli

Roberto Giacomelli

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Roberto Giacomelli

Roberto Giacomelli

Publications by authors named "Roberto Giacomelli"

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Prescribing motivations and patients' characteristics related to the use of biologic drugs in adult-onset Still's disease: analysis of a multicentre "real-life" cohort.

Rheumatol Int 2020 Jan 1;40(1):107-113. Epub 2019 Jul 1.

Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, PO box 67100, L'Aquila, Italy.

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http://dx.doi.org/10.1007/s00296-019-04358-wDOI Listing
January 2020

Certolizumab pegol for the treatment of psoriatic arthritis and plaque psoriasis.

Expert Rev Clin Immunol 2020 Jan 9. Epub 2020 Jan 9.

Dermatology Unit, Department of Biotechnological and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1080/1744666X.2020.1713754DOI Listing
January 2020

Hyaluronic acid and platelet-rich plasma, a new therapeutic alternative for scleroderma patients: a prospective open-label study.

Arthritis Res Ther 2019 Dec 13;21(1):286. Epub 2019 Dec 13.

Dipartimento di Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza "G. D'Alessandro", Sezione di Reumatologia, University of Palermo, Palermo, Italy.

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http://dx.doi.org/10.1186/s13075-019-2062-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911298PMC
December 2019

Macrophages with regulatory functions, a possible new therapeutic perspective in autoimmune diseases.

Autoimmun Rev 2019 Oct 9;18(10):102369. Epub 2019 Aug 9.

University of L'Aquila, Department of Biotechnological and Applied Clinical Sciences, Rheumatology Unit, L'Aquila, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S15689972193016
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http://dx.doi.org/10.1016/j.autrev.2019.102369DOI Listing
October 2019

The kaleidoscope of neurological manifestations in primary Sjögren's syndrome.

Clin Exp Rheumatol 2019 May-Jun;37 Suppl 118(3):192-198. Epub 2019 Aug 28.

Rheumatology Unit, Department of Medicine, University of Perugia, Italy.

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October 2019

Vitamin D increases the production of IL-10 by regulatory T cells in patients with systemic sclerosis.

Clin Exp Rheumatol 2019 Jul-Aug;37 Suppl 119(4):76-81. Epub 2019 Oct 3.

Dipartimento Biomedico di Medicina Interna e Specialistica, Sezione di Reumatologia, University of Palermo, Italy.

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October 2019

Mediterranean diet and Psoriatic Arthritis activity: a multicenter cross-sectional study.

Rheumatol Int 2019 Oct 11. Epub 2019 Oct 11.

Rheumatology Unit, Department of Clinical Medicine and Surgery, School of Medicine, University Federico II of Naples, Via S. Pansini 5, 80131, Naples, Italy.

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http://dx.doi.org/10.1007/s00296-019-04458-7DOI Listing
October 2019

Linking myofibroblast generation and microvascular alteration: The role of CD248 from pathogenesis to therapeutic target (Review).

Mol Med Rep 2019 Aug 26;20(2):1488-1498. Epub 2019 Jun 26.

Department of Biotechnological and Applied Clinical Sciences, Rheumatology Unit, School of Medicine, University of L'Aquila, L'Aquila I‑67100, Italy.

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http://dx.doi.org/10.3892/mmr.2019.10429DOI Listing
August 2019

Inflammation and Dysmetabolism in Systemic Autoimmune Diseases.

J Immunol Res 2019 22;2019:5438287. Epub 2019 Jul 22.

Division of Rheumatology, Department of Biotechnological and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1155/2019/5438287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679857PMC
July 2019

The Vessels Contribute to Fibrosis in Systemic Sclerosis.

Isr Med Assoc J 2019 Jul;21(7):471-474

Unit of Rheumatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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July 2019

Post-Translational Modifications of Proteins: Novel Insights in the Autoimmune Response in Rheumatoid Arthritis.

Cells 2019 06 29;8(7). Epub 2019 Jun 29.

Rheumatology Unit, Department of Biotechnological and Applied Clinical Science, School of Medicine, University of L'Aquila, 67100 L'Aquila, Italy.

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http://dx.doi.org/10.3390/cells8070657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678491PMC
June 2019

The effect of non-TNF-targeted biologics on vascular dysfunction in rheumatoid arthritis: A systematic literature review.

Autoimmun Rev 2019 May 4;18(5):501-509. Epub 2019 Mar 4.

Internal Medicine Unit, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1016/j.autrev.2019.03.008DOI Listing
May 2019

Laboratory Assessment of Patients with Suspected Rheumatic Musculoskeletal Diseases: Challenges and Pitfalls.

Curr Rheumatol Rev 2019 ;15(1):27-43

Rheumatology Unit, Department of Biotechnological and Applied Clinical Science, School of Medicine, University of L'Aquila, L'Aquila, AQ, Italy.

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http://dx.doi.org/10.2174/1573397114666180320113603DOI Listing
April 2019

Safety and efficacy of certolizumab pegol in a real-life cohort of patients with psoriasis and psoriatic arthritis.

J Dermatolog Treat 2019 Apr 9:1-6. Epub 2019 Apr 9.

d Dermatology Department, Department of Biotechnological and Applied Clinical Science, School of Medicine , University of L'Aquila , L'Aquila , Italy.

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http://dx.doi.org/10.1080/09546634.2019.1605143DOI Listing
April 2019

Epidermal Growth Factor Like-domain 7 and miR-126 are abnormally expressed in diffuse Systemic Sclerosis fibroblasts.

Sci Rep 2019 Mar 14;9(1):4589. Epub 2019 Mar 14.

Department of Biotechnological and Applied Clinical Science, Rheumatology Unit, School of Medicine, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.

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http://www.nature.com/articles/s41598-019-39485-8
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http://dx.doi.org/10.1038/s41598-019-39485-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418261PMC
March 2019

Adipocytokines in Rheumatoid Arthritis: The Hidden Link between Inflammation and Cardiometabolic Comorbidities.

J Immunol Res 2018 21;2018:8410182. Epub 2018 Nov 21.

Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Delta 6 Building, L'Aquila, PO Box 67100, Italy.

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https://www.hindawi.com/journals/jir/2018/8410182/
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http://dx.doi.org/10.1155/2018/8410182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280248PMC
February 2019

Adipose stromal vascular fraction and regenerative therapy in SSc: response to the article by Magalon .

Ann Rheum Dis 2019 Feb 2. Epub 2019 Feb 2.

Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1136/annrheumdis-2019-215113DOI Listing
February 2019

The Emerging Role of IL-1 Inhibition in Patients Affected by Rheumatoid Arthritis and Diabetes.

Rev Recent Clin Trials 2018;13(3):210-214

Rheumatology Section, Department of Biotechnological and Applied Clinical Sciences, University of L`Aquila, L`Aquila, Italy.

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http://dx.doi.org/10.2174/1574887113666180314102651DOI Listing
December 2018

Prevalence and significance of anti-saccharomyces cerevisiae antibodies in primary Sjögren's syndrome.

Clin Exp Rheumatol 2018 May-Jun;36 Suppl 112(3):73-79. Epub 2017 Jun 29.

Rheumatology Unit, Department of Medicine, University of Perugia, Italy.

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November 2018

The role of extracellular matrix components in angiogenesis and fibrosis: Possible implication for Systemic Sclerosis.

Mod Rheumatol 2018 Nov 15;28(6):922-932. Epub 2018 Feb 15.

a Department of Biotechnological and Applied Clinical Science, Rheumatology Unit, School of Medicine , University of L'Aquila , L'Aquila , Italy.

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http://dx.doi.org/10.1080/14397595.2018.1431004DOI Listing
November 2018

Pathogenesis of adult onset still's disease: current understanding and new insights.

Expert Rev Clin Immunol 2018 11 12;14(11):965-976. Epub 2018 Oct 12.

a Division of Rheumatology, Department of Biotechnological and Applied Clinical Sciences , University of L'Aquila , L'Aquila , Italy.

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http://dx.doi.org/10.1080/1744666X.2018.1533403DOI Listing
November 2018

Cardiovascular and Metabolic Comorbidities in Rheumatoid Arthritis.

Curr Rheumatol Rep 2018 11 5;20(12):81. Epub 2018 Nov 5.

Rheumatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100, L'Aquila, Italy.

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http://link.springer.com/10.1007/s11926-018-0790-9
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http://dx.doi.org/10.1007/s11926-018-0790-9DOI Listing
November 2018

Tailored approach to rheumatoid arthritis treatment with TNF inhibitors: where do we stand?

Rheumatology (Oxford) 2018 10;57(57 Suppl 7):vii1-vii4

Department of Biotechnological and Applied Clinical Science, Rheumatology Unit, School of Medicine, University of L'Aquila, L'Aquila, Italy.

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https://academic.oup.com/rheumatology/article/57/Supplement_
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http://dx.doi.org/10.1093/rheumatology/key259DOI Listing
October 2018

Downregulation of miRNA17-92 cluster marks Vγ9Vδ2 T cells from patients with rheumatoid arthritis.

Arthritis Res Ther 2018 Oct 22;20(1):236. Epub 2018 Oct 22.

Central Laboratory of Advanced Diagnosis and Biomedical Research (CLADIBIOR), Azienda Ospedaliera Universitaria Policlinico P. Giaccone, Palermo, Italy.

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https://arthritis-research.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s13075-018-1740-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235230PMC
October 2018

A comprehensive review on adult onset Still's disease.

J Autoimmun 2018 09 1;93:24-36. Epub 2018 Aug 1.

Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

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http://dx.doi.org/10.1016/j.jaut.2018.07.018DOI Listing
September 2018

Clinical, Epidemiological, and Histopathological Features of Respiratory Involvement in Rheumatoid Arthritis.

Biomed Res Int 2017 7;2017:7915340. Epub 2017 Nov 7.

Rheumatology Unit, Department of Biotechnological and Applied Clinical Science, School of Medicine, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1155/2017/7915340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697381PMC
July 2018

The challenge to interpret conflicting results and the need of a univocal definition for germinal centres in primary Sjögren's syndrome.

Ann Rheum Dis 2018 06 10;77(6):e31. Epub 2017 Aug 10.

Department of Medicine, Rheumatology Unit, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1136/annrheumdis-2017-212108DOI Listing
June 2018

Macrophage Activation Syndrome in Patients Affected by Adult-onset Still Disease: Analysis of Survival Rates and Predictive Factors in the Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale Cohort.

J Rheumatol 2018 06 15;45(6):864-872. Epub 2018 Apr 15.

From the Rheumatology Section, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila; Rheumatology Section, Department of Clinical and Experimental Medicine, Second University of Naples, Naples; Rheumatology Section, Department of Internal Medicine, University of Palermo, Palermo; Department of Experimental and Clinical Medicine, University of Florence, Florence; Department of Health Sciences, University of Catanzaro "Magna Graecia," Catanzaro; Systemic Rheumatic and Autoimmune Diseases Unit, Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Bari, Italy.

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http://dx.doi.org/10.3899/jrheum.170955DOI Listing
June 2018

Oxidized low density lipoproteins: The bridge between atherosclerosis and autoimmunity. Possible implications in accelerated atherosclerosis and for immune intervention in autoimmune rheumatic disorders.

Autoimmun Rev 2018 Apr 7;17(4):366-375. Epub 2018 Feb 7.

Department of Biomedical Sciences and Human Oncology (DIMO), Systemic Rheumatic and Autoimmune Diseases Unit, University of Bari Medical School, Bari, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15689972183003
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http://dx.doi.org/10.1016/j.autrev.2017.11.028DOI Listing
April 2018

The effect of non-TNF-targeted biologics and small molecules on insulin resistance in inflammatory arthritis.

Autoimmun Rev 2018 Apr 13;17(4):399-404. Epub 2018 Feb 13.

Department of Health Sciences, University of Catanzaro "Magna Graecia", Catanzaro, Italy.

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http://dx.doi.org/10.1016/j.autrev.2017.11.030DOI Listing
April 2018

Lymphoma and Lymphomagenesis in Primary Sjögren's Syndrome.

Front Med (Lausanne) 2018 13;5:102. Epub 2018 Apr 13.

Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.3389/fmed.2018.00102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909032PMC
April 2018

Vitamin D and systemic lupus erythematosus - The hype and the hope.

Autoimmun Rev 2018 Jan 3;17(1):19-23. Epub 2017 Nov 3.

Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Faculty of Biology Medicine and Health, The University of Manchester, UK; NIHR Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1016/j.autrev.2017.11.004DOI Listing
January 2018

Macrophage activation syndrome in Still's disease: analysis of clinical characteristics and survival in paediatric and adult patients.

Clin Rheumatol 2017 Dec 15;36(12):2839-2845. Epub 2017 Sep 15.

Division of Rheumatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1007/s10067-017-3830-3DOI Listing
December 2017

Biologic drugs in adult onset Still's disease: a systematic review and meta-analysis of observational studies.

Expert Rev Clin Immunol 2017 11 21;13(11):1089-1097. Epub 2017 Sep 21.

a Division of Rheumatology, Department of Biotechnological and Applied Clinical Sciences , University of L'Aquila , L'Aquila , Italy.

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http://dx.doi.org/10.1080/1744666X.2017.1375853DOI Listing
November 2017

Cytokines in the pathogenesis of rheumatoid arthritis: new players and therapeutic targets.

BMC Rheumatol 2017 28;1. Epub 2017 Nov 28.

1Rheumatology Unit, Department of Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1186/s41927-017-0001-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383595PMC
November 2017

Subclinical atherosclerosis and history of cardiovascular events in Italian patients with rheumatoid arthritis: Results from a cross-sectional, multicenter GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) study.

Medicine (Baltimore) 2017 Oct;96(42):e8180

aRheumatology Section, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila bClinical Medicine and Rheumatology Department, Campus Bio-Medico University of Rome, Rome cRheumatology Section, Department of Internal Medicine, University of Palermo, Palermo dRheumatology Section, Department of Clinical and Experimental Medicine, Second University of Naples, Naples eRheumatology Section, Department of Medical and Surgical Sciences, University of Foggia Medical School, Foggia fDepartment of Experimental and Clinical Medicine, University of Florence, Florence gRheumatology Section, L. Sacco University Hospital, Milan hSystemic Rheumatic and Autoimmune Diseases Unit, Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Bari, Italy.

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http://dx.doi.org/10.1097/MD.0000000000008180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662366PMC
October 2017

International consensus: What else can we do to improve diagnosis and therapeutic strategies in patients affected by autoimmune rheumatic diseases (rheumatoid arthritis, spondyloarthritides, systemic sclerosis, systemic lupus erythematosus, antiphospholipid syndrome and Sjogren's syndrome)?: The unmet needs and the clinical grey zone in autoimmune disease management.

Autoimmun Rev 2017 Sep 11;16(9):911-924. Epub 2017 Jul 11.

Department of Pathophysiology, University of Athens, Athens, Greece.

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http://dx.doi.org/10.1016/j.autrev.2017.07.012DOI Listing
September 2017

Computed Tomography and MR Imaging in Rheumatoid Arthritis.

Radiol Clin North Am 2017 Sep 12;55(5):997-1007. Epub 2017 Jun 12.

Diagnostic and Interventional Radiology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio 1, L'Aquila, Coppito 67100, Italy.

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http://dx.doi.org/10.1016/j.rcl.2017.04.006DOI Listing
September 2017

Correlation between ESSDAI and ClinESSDAI in a real-life cohort of patients with Sjögren's syndrome.

Clin Exp Rheumatol 2017 May-Jun;35(3):546-547. Epub 2017 Feb 10.

Rheumatology Clinic, Department of Medical and Biological Sciences, Azienda Ospedaliero-Universitaria 'S. Maria della Misericordia', Udine, Italy.

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August 2017

Cryoglobulinemia in Sjögren Syndrome: A Disease Subset that Links Higher Systemic Disease Activity, Autoimmunity, and Local B Cell Proliferation in Mucosa-associated Lymphoid Tissue.

J Rheumatol 2017 08 15;44(8):1179-1183. Epub 2017 May 15.

From the Rheumatology Clinic, Department of Medical and Biological Sciences, Azienda Ospedaliero-Universitaria S. Maria della Misericordia, Udine; Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa; Rheumatology Unit, Sapienza University of Rome, Rome; Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Perugia; Rheumatology Unit, University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.3899/jrheum.161465DOI Listing
August 2017

Prevalence of type 2 diabetes and impaired fasting glucose in patients affected by rheumatoid arthritis: Results from a cross-sectional study.

Medicine (Baltimore) 2017 Aug;96(34):e7896

aDivision of Rheumatology, Department of Biotechnological and Applied Clinical Science, University of L'Aquila, L'Aquila bDepartment of Health Sciences, University of Catanzaro "Magna Graecia", Catanzaro cDivision of Rheumatology, Department of Internal Medicine, University of Palermo, Palermo, Italy.

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http://dx.doi.org/10.1097/MD.0000000000007896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572029PMC
August 2017

Persistence of focal lymphocytic sialadenitis in patients with primary Sjögren's syndrome treated with rituximab: a possible role for glandular BAFF.

Clin Exp Rheumatol 2016 Nov-Dec;34(6):1123-1124. Epub 2016 Aug 2.

Department of Biotechnological and Applied Clinical Sciences, Rheumatology Unit, University of L'Aquila, Italy.

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June 2017

Interstitial lung disease in systemic sclerosis: current and future treatment.

Rheumatol Int 2017 Jun 6;37(6):853-863. Epub 2017 Jan 6.

Department of Biotechnological and Applied Clinical Science, Rheumatology Unit, School of Medicine, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.

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http://dx.doi.org/10.1007/s00296-016-3636-7DOI Listing
June 2017

Adult-onset Still's disease: evaluation of prognostic tools and validation of the systemic score by analysis of 100 cases from three centers.

BMC Med 2016 Dec 1;14(1):194. Epub 2016 Dec 1.

Rheumatology Section, Department of Biotechnological and Applied Clinical Science, School of Medicine, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.

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http://dx.doi.org/10.1186/s12916-016-0738-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131497PMC
December 2016

Endothelial progenitor cells: Are they displaying a function in autoimmune disorders?

Mech Ageing Dev 2016 10 3;159:44-48. Epub 2016 May 3.

Dipartimento di Medicina Interna e Specialistica, Sezione di Reumatologia, Università degli Studi di Palermo, Italy.

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http://dx.doi.org/10.1016/j.mad.2016.05.001DOI Listing
October 2016

Mesenchymal Stem Cell Transplantation in Systemic Sclerosis: Comment on the Article by Maria et al.

Arthritis Rheumatol 2016 09;68(9):2348

University of L'Aquila, L'Aquila, Italy.

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http://dx.doi.org/10.1002/art.39754DOI Listing
September 2016

IL-1β at the crossroad between rheumatoid arthritis and type 2 diabetes: may we kill two birds with one stone?

Expert Rev Clin Immunol 2016 Aug 12;12(8):849-55. Epub 2016 Apr 12.

a Division of Rheumatology, Department of Biotechnological and Applied Clinical Science , School of Medicine, University of L'Aquila , L'Aquila , Italy.

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http://dx.doi.org/10.1586/1744666X.2016.1168293DOI Listing
August 2016

Targeting the IL-23/IL-17 axis for the treatment of psoriasis and psoriatic arthritis.

Expert Opin Biol Ther 2015 7;15(12):1727-37. Epub 2015 Sep 7.

a 1 University of Perugia, Department of Medicine , Perugia, Italy.

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http://dx.doi.org/10.1517/14712598.2015.1084284DOI Listing
July 2016

Perivascular Cells in Diffuse Cutaneous Systemic Sclerosis Overexpress Activated ADAM12 and Are Involved in Myofibroblast Transdifferentiation and Development of Fibrosis.

J Rheumatol 2016 07 1;43(7):1340-9. Epub 2016 Jun 1.

From the Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, and the Department of Applied Clinical Sciences and Biotechnology, General Pathology Unit, University of L'Aquila, L'Aquila; Dipartimento Biomedico di Medicina Interna e Specialistica, Sezione di Reumatologia, Università degli Studi di Palermo, Palermo, Italy.P. Cipriani, MD, PhD, Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, University of L'Aquila; P. Di Benedetto, PhD, Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, University of L'Aquila; P. Ruscitti, MD, Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, University of L'Aquila; V. Liakouli, MD, PhD, Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, University of L'Aquila; O. Berardicurti, MD, Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, University of L'Aquila; F. Carubbi, MD, Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, University of L'Aquila; F. Ciccia, MD, PhD, Dipartimento Biomedico di Medicina Interna e Specialistica, Sezione di Reumatologia, Università degli Studi di Palermo; G. Guggino, MD, Dipartimento Biomedico di Medicina Interna e Specialistica, Sezione di Reumatologia, Università degli Studi di Palermo; F. Zazzeroni, PhD, Department of Applied Clinical Sciences and Biotechnology, General Pathology Unit, University of L'Aquila; E. Alesse, MD, PhD, Department of Applied Clinical Sciences and Biotechnology, General Pathology Unit, University of L'Aquila; G. Triolo, MD, PhD, Dipartimento Biomedico di Medicina Interna e Specialistica, Sezione di Reumatologia, Università degli Studi di Palermo; R. Giacomelli, MD, PhD, Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School

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http://dx.doi.org/10.3899/jrheum.150996DOI Listing
July 2016

Anti-SSA/SSB-negative Sjögren's syndrome shows a lower prevalence of lymphoproliferative manifestations, and a lower risk of lymphoma evolution.

Autoimmun Rev 2015 Nov 8;14(11):1019-22. Epub 2015 Jul 8.

Rheumatology Clinic, Department of Medical and Biological Sciences, Azienda Ospedaliero-Universitaria "S. Maria della Misericordia", Udine, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2015.07.002DOI Listing
November 2015

The Endothelial-mesenchymal Transition in Systemic Sclerosis Is Induced by Endothelin-1 and Transforming Growth Factor-β and May Be Blocked by Macitentan, a Dual Endothelin-1 Receptor Antagonist.

J Rheumatol 2015 Oct 15;42(10):1808-16. Epub 2015 Aug 15.

From the Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, and the Department of Applied Clinical Sciences and Biotechnology, General Phatology Unit, University of L'Aquila, L'Aquila; Medical and Scientific Direction, Actelion Pharmaceuticals Italy, Imola, Italy; Drug Discovery Department, Actelion Pharmaceuticals Ltd., Allschwil, Switzerland.P. Cipriani, MD, PhD; P. Di Benedetto, PhD; P. Ruscitti, MD, Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, University of L'Aquila; D. Capece, PhD; F. Zazzeroni, PhD, Department of Applied Clinical Sciences and Biotechnology, General Phatology Unit, University of L'Aquila; V. Liakouli, MD, PhD; I. Pantano, MD; O. Berardicurti, MD; F. Carubbi, MD, Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, University of L'Aquila; G. Pecetti, MD; S. Turricchia, MD, Medical and Scientific Direction, Actelion Pharmaceuticals Italy; E. Alesse, MD, PhD, Department of Applied Clinical Sciences and Biotechnology, General Pathology Unit, University of L'Aquila; M. Iglarz, PhD, Drug Discovery Department, Actelion Pharmaceuticals Ltd.; R. Giacomelli, MD, PhD, Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, University of L'Aquila.

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http://dx.doi.org/10.3899/jrheum.150088DOI Listing
October 2015

Macitentan inhibits the transforming growth factor-β profibrotic action, blocking the signaling mediated by the ETR/TβRI complex in systemic sclerosis dermal fibroblasts.

Arthritis Res Ther 2015 Sep 10;17:247. Epub 2015 Sep 10.

Department of Applied Clinical Sciences and Biotechnology, Rheumatology Unit, School of Medicine, University of L'Aquila, Delta 6 Building, Via dell'Ospedale, 67100, L'Aquila, Italy.

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http://dx.doi.org/10.1186/s13075-015-0754-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566861PMC
September 2015