Publications by authors named "Roberto Chiarle"

98Publications

Complete and prolonged response to anti-PD1 therapy in an ALK rearranged lung adenocarcinoma.

Lung Cancer 2020 08 27;146:366-369. Epub 2020 May 27.

Univ Lille, Department of Thoracic Oncology, CHU Lille, F-59000, Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.05.008DOI Listing
August 2020

CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation.

Cell Rep 2019 07;28(5):1307-1322.e8

Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.06.079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684324PMC
July 2019

RHO Family GTPases in the Biology of Lymphoma.

Cells 2019 06 26;8(7). Epub 2019 Jun 26.

Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.

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http://dx.doi.org/10.3390/cells8070646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678807PMC
June 2019

Comment on "ALK is a therapeutic target for lethal sepsis".

Sci Transl Med 2018 12;10(471)

Department of Pathology, Children's Hospital Boston and Harvard Medical School, Boston, MA 02115 USA.

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http://dx.doi.org/10.1126/scitranslmed.aar4321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459396PMC
December 2018

The CRISPR/Cas9 System as a Tool to Engineer Chromosomal Translocation In Vivo.

Adv Exp Med Biol 2018 ;1044:39-48

Department of Pathology, Boston Children's Hospital, Boston, MA, USA.

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http://link.springer.com/10.1007/978-981-13-0593-1_4
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http://dx.doi.org/10.1007/978-981-13-0593-1_4DOI Listing
November 2018

Tumor Resistance against ALK Targeted Therapy-Where It Comes From and Where It Goes.

Cancers (Basel) 2018 Feb 28;10(3). Epub 2018 Feb 28.

Department of Molecular Biotechnology and Health Sciences, University of Turin, Turin 10124, Italy.

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http://dx.doi.org/10.3390/cancers10030062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876637PMC
February 2018

KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS.

Cell 2018 02 11;172(4):857-868.e15. Epub 2018 Jan 11.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.12.020DOI Listing
February 2018

Combined immunodeficiency with EBV positive B cell lymphoma and epidermodysplasia verruciformis due to a novel homozygous mutation in RASGRP1.

Clin Immunol 2017 10 16;183:142-144. Epub 2017 Aug 16.

Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2017.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673555PMC
October 2017

A Braf kinase-inactive mutant induces lung adenocarcinoma.

Nature 2017 08 2;548(7666):239-243. Epub 2017 Aug 2.

Experimental Oncology, Molecular Oncology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO), 28029 Madrid, Spain.

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http://dx.doi.org/10.1038/nature23297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648056PMC
August 2017

Maternal Immunization: New Perspectives on Its Application Against Non-Infectious Related Diseases in Newborns.

Vaccines (Basel) 2017 Aug 1;5(3). Epub 2017 Aug 1.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino 10126, Italy.

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http://dx.doi.org/10.3390/vaccines5030020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620551PMC
August 2017

Developmentally-faithful and effective human erythropoiesis in immunodeficient and Kit mutant mice.

Am J Hematol 2017 Sep 19;92(9):E513-E519. Epub 2017 Jul 19.

Division of Hematology/Oncology, The Manton Center for Orphan Disease Research, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ajh.24805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546987PMC
September 2017

Primary Cutaneous B-Cell Lymphoblastic Lymphoma Arising from a Long-Standing Lesion in a Child and Review of the Literature.

Pediatr Dermatol 2017 Jul 26;34(4):e182-e186. Epub 2017 May 26.

Dermatology Program, Boston Children's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1111/pde.13169DOI Listing
July 2017

Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by single-molecule RNA fluorescence in situ hybridization.

Oncotarget 2017 Mar;8(12):18680-18698

Department of Medical Biochemistry and Biophysics, Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.18632/oncotarget.15727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386639PMC
March 2017

Advances in cancer immunology and cancer immunotherapy.

Discov Med 2016 Feb;21(114):125-33

Department of Pathology, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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February 2016

Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system.

Nat Commun 2016 Mar 9;7:10934. Epub 2016 Mar 9.

Department of Pathology, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ncomms10934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786874PMC
March 2016

Redundant and nonredundant roles for Cdc42 and Rac1 in lymphomas developed in NPM-ALK transgenic mice.

Blood 2016 Mar 8;127(10):1297-306. Epub 2016 Jan 8.

Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy; Center for Experimental Medicine and Clinical Studies, University of Torino, Torino, Italy; Department of Pathology, Boston Children's Hospital, Boston, MA; and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1182/blood-2015-11-683052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786839PMC
March 2016

The anaplastic lymphoma kinase as an oncogene in solid tumors.

Front Biosci (Schol Ed) 2015 Jun 1;7:269-82. Epub 2015 Jun 1.

Department of Pathology, Children's Hospital Boston, Associate Professor in Pathology, Harvard Medical School, Enders 1116.1., 300 Longwood Ave, Boston, MA 02115,

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June 2015

Simple and rapid in vivo generation of chromosomal rearrangements using CRISPR/Cas9 technology.

Cell Rep 2014 Nov 13;9(4):1219-27. Epub 2014 Nov 13.

Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.10.051DOI Listing
November 2014

STAT3β controls inflammatory responses and early tumor onset in skin and colon experimental cancer models.

Am J Cancer Res 2014 6;4(5):484-94. Epub 2014 Sep 6.

Department of Molecular Biotechnology and Health Sciences, University of Turin Turin, 10126, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163613PMC
September 2014

Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts.

Cancer Res 2014 Nov 12;74(21):5978-88. Epub 2014 Sep 12.

Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain. XenOPAT S.L., Business Bioincubator, Bellvitge Health Science Campus, Barcelona, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1606DOI Listing
November 2014

ALK-dependent control of hypoxia-inducible factors mediates tumor growth and metastasis.

Cancer Res 2014 Nov 5;74(21):6094-106. Epub 2014 Sep 5.

Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy. Center for Experimental Research and Medical Studies (CERMS), Torino, Italy. Department of Pathology, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0268DOI Listing
November 2014

IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances.

Proc Natl Acad Sci U S A 2014 Feb 3;111(7):2644-9. Epub 2014 Feb 3.

Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, and Department of Genetics, Harvard Medical School, Boston, MA 02115.

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http://dx.doi.org/10.1073/pnas.1324176111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932927PMC
February 2014

FuseFISH: robust detection of transcribed gene fusions in single cells.

Cell Rep 2014 Jan 27;6(1):18-23. Epub 2013 Dec 27.

Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2013.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214547PMC
January 2014

Translocations in normal B cells and cancers: insights from new technical approaches.

Authors:
Roberto Chiarle

Adv Immunol 2013 ;117:39-71

Department of Pathology, Children's Hospital Boston and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/B978-0-12-410524-9.00002-5DOI Listing
August 2013

Vaccination with ENO1 DNA prolongs survival of genetically engineered mice with pancreatic cancer.

Gastroenterology 2013 May 16;144(5):1098-106. Epub 2013 Jan 16.

Center for Experimental Research and Medical Studies, Città della Salute e della Scienza di Torino, Italy.

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http://dx.doi.org/10.1053/j.gastro.2013.01.020DOI Listing
May 2013

Tissue flow cytometry immunophenotyping in the diagnosis and classification of non-Hodgkin's lymphomas: a retrospective evaluation of 1,792 cases.

Cytometry B Clin Cytom 2013 Mar 16;84(2):82-95. Epub 2013 Jan 16.

Flow Cytometry Unit, Anatomical Pathology Laboratory 2, Molinette Hospital, University of Turin, Italy.

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http://dx.doi.org/10.1002/cyto.b.21065DOI Listing
March 2013

The battle against ALK resistance: successes and setbacks.

Expert Opin Investig Drugs 2012 Dec 25;21(12):1751-4. Epub 2012 Aug 25.

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http://dx.doi.org/10.1517/13543784.2012.717930DOI Listing
December 2012

Calming down T cell acute leukemia.

Cancer Cell 2012 Apr;21(4):449-50

Molecular Biotechnology Center, University of Torino, Torino, Italy.

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http://dx.doi.org/10.1016/j.ccr.2012.03.025DOI Listing
April 2012

FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas.

Nature 2012 Jan;481(7379):90-3

Department of Pathology, NYU Cancer Institute, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1038/nature10688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3344385PMC
January 2012

Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells.

Cell 2011 Sep;147(1):107-19

Howard Hughes Medical Institute, Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.cell.2011.07.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186939PMC
September 2011

Mechanisms that promote and suppress chromosomal translocations in lymphocytes.

Annu Rev Immunol 2011 ;29:319-50

Howard Hughes Medical Institute, Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1146/annurev-immunol-031210-101329DOI Listing
June 2011

Expression of IFNγR2 mutated in a dileucine internalization motif reinstates IFNγ signaling and apoptosis in human T lymphocytes.

Immunol Lett 2010 Nov 13;134(1):17-25. Epub 2010 Aug 13.

Center for Experimental Research and Medical Studies, San Giovanni Battista Hospital, University of Turin, 10126 Turin, Italy.

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http://dx.doi.org/10.1016/j.imlet.2010.08.005DOI Listing
November 2010

NPM-ALK oncogenic tyrosine kinase controls T-cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells.

Cancer Res 2009 Nov 3;69(22):8611-9. Epub 2009 Nov 3.

Department of Biomedical Sciences and Human Oncology, University of Torino, Center for Experimental Research and Medical Studies, ASO San Giovanni Battista, Torino, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784121PMC
November 2009

Anaplastic large cell lymphoma: one or more entities among T-cell lymphoma?

Hematol Oncol 2009 Dec;27(4):161-70

Department of Pathology and Center for Experimental Research and Medical Studies (CeRMS), University of Torino, Italy.

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http://dx.doi.org/10.1002/hon.897DOI Listing
December 2009

Anaplastic lymphoma kinase: an oncogene for tumor vaccination.

J Mol Med (Berl) 2009 Jul 30;87(7):669-77. Epub 2009 Mar 30.

Center for Experimental Research and Medical Studies (CERMS), University of Turin, Via Santena 7, 10126, Turin, Italy.

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http://link.springer.com/content/pdf/10.1007/s00109-009-0460
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http://link.springer.com/10.1007/s00109-009-0460-5
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http://dx.doi.org/10.1007/s00109-009-0460-5DOI Listing
July 2009

The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation.

Cancer Res 2008 Nov;68(21):8899-907

Department of Biomedical Sciences and Human Oncology, Center for Experimental Research and Medical Studies, University of Torino, Turin, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596920PMC
November 2008

Heat shock protein expression in diabetic nephropathy.

Am J Physiol Renal Physiol 2008 Dec 15;295(6):F1817-24. Epub 2008 Oct 15.

Dept. of Internal Medicine, Univ. of Turin, Corso AM Dogliotti 14. Turin, 10126, Italy.

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http://dx.doi.org/10.1152/ajprenal.90234.2008DOI Listing
December 2008

Of alphas and betas: distinct and overlapping functions of STAT3 isoforms.

Front Biosci 2008 May 1;13:6501-14. Epub 2008 May 1.

Molecular Biotechnology Center, University of Turin, Via Nizza 52, 10126 Turin, Italy.

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http://dx.doi.org/10.2741/3170DOI Listing
May 2008

The anaplastic lymphoma kinase is an effective oncoantigen for lymphoma vaccination.

Nat Med 2008 Jun 11;14(6):676-80. Epub 2008 May 11.

Center for Experimental Research and Medical Studies, University of Torino, Via Santena 7, 10126 Torino, Italy.

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http://dx.doi.org/10.1038/nm1769DOI Listing
June 2008

High energy shock waves (HESW) increase paclitaxel efficacy in a syngeneic model of breast cancer.

Technol Cancer Res Treat 2008 Apr;7(2):117-24

Department of Clinical Pathophysiology, University of Torino, Via Genova 3, Torino, Italy.

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http://dx.doi.org/10.1177/153303460800700204DOI Listing
April 2008

The anaplastic lymphoma kinase in the pathogenesis of cancer.

Nat Rev Cancer 2008 Jan;8(1):11-23

Center for Experimental Research and Medical Studies (CERMS), University of Torino, Via Santena 7, 10126, Italy.

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http://dx.doi.org/10.1038/nrc2291DOI Listing
January 2008

Autoantibody signature in human ductal pancreatic adenocarcinoma.

J Proteome Res 2007 Oct 8;6(10):4025-31. Epub 2007 Sep 8.

Center for Experimental Research and Medical Studies and University of Turin, San Giovanni Battista Hospital, Turin, Italy.

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http://dx.doi.org/10.1021/pr070281aDOI Listing
October 2007

Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma.

Proc Natl Acad Sci U S A 2007 Sep 24;104(36):14354-9. Epub 2007 Aug 24.

Dipartimento di Genetica, Biologia e Biochimica, Molecular Biotechnology Center, University of Torino, Via Nizza 52, 10126 Torino, Italy.

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http://dx.doi.org/10.1073/pnas.0703175104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952139PMC
September 2007

The Down syndrome critical region protein TTC3 inhibits neuronal differentiation via RhoA and Citron kinase.

J Cell Sci 2007 Jun 8;120(Pt 11):1859-67. Epub 2007 May 8.

Molecular Biotechnology Center, Department of Genetics, Biology and Biochemistry, University of Turin, Italy.

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http://dx.doi.org/10.1242/jcs.000703DOI Listing
June 2007

Conditional activation of MET in differentiated skeletal muscle induces atrophy.

J Biol Chem 2007 Mar 27;282(9):6812-22. Epub 2006 Dec 27.

Center for Experimental Research and Medical Studies, University of Turin, 10126 Turin, Italy.

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http://dx.doi.org/10.1074/jbc.M610916200DOI Listing
March 2007

In the absence of IGF-1 signaling, IFN-gamma suppresses human malignant T-cell growth.

Blood 2007 Mar 5;109(6):2496-504. Epub 2006 Dec 5.

Center for Experimental Research and Medical Studies (CERMS), San Giovanni Battista Hospital, Turin, Italy.

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http://dx.doi.org/10.1182/blood-2006-07-034231DOI Listing
March 2007

Incestuous paternity detected by STR-typing of chorionic villi isolated from archival formalin-fixed paraffin-embedded abortion material using laser microdissection.

J Forensic Sci 2006 Jan;51(1):90-2

Laboratory of Criminalistic Sciences, Department of Anatomy, Pharmacology and Legal Medicine, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1111/j.1556-4029.2005.00013.xDOI Listing
January 2006

p130Cas mediates the transforming properties of the anaplastic lymphoma kinase.

Blood 2005 Dec 16;106(12):3907-16. Epub 2005 Aug 16.

Center for Experimental Research and Medical Studies and Department of Biomedical Sciences and Human Oncology, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1182/blood-2005-03-1204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895100PMC
December 2005

New and old functions of STAT3: a pivotal target for individualized treatment of cancer.

Cell Cycle 2005 Sep 30;4(9):1131-3. Epub 2005 Sep 30.

Department of Pathology, NYU Cancer Institute, New York University School of Medicine, New York, New York 10016, USA.

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https://www.tandfonline.com/doi/full/10.4161/cc.4.9.1985
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http://dx.doi.org/10.4161/cc.4.9.1985DOI Listing
September 2005

Follicular origin of a subset of CD5+ diffuse large B-cell lymphomas.

Am J Clin Pathol 2005 Aug;124(2):182-90

Center for Experimental Research and Medical Studies and Department of Biomedical Sciences and Human Oncology, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1309/8EX5-B9JF-HPEK-82BUDOI Listing
August 2005

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target.

Nat Med 2005 Jun 15;11(6):623-9. Epub 2005 May 15.

Department of Pathology and NYU Cancer Institute, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1038/nm1249DOI Listing
June 2005

The STAT3 isoforms alpha and beta have unique and specific functions.

Nat Immunol 2004 Apr 14;5(4):401-9. Epub 2004 Mar 14.

Department of Genetics, Biology and Biochemistry, University of Turin, 10126 Turin, Italy.

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http://www.nature.com/articles/ni1052
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http://dx.doi.org/10.1038/ni1052DOI Listing
April 2004

Confocal microscope analysis and tridimensional reconstruction of papillary thyroid carcinoma nuclei.

Virchows Arch 2004 Apr 31;444(4):350-5. Epub 2004 Jan 31.

Department of Biomedical Sciences and Oncology, University of Turin, Via Santena 7, 10126 Turin, Italy.

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http://dx.doi.org/10.1007/s00428-003-0962-4DOI Listing
April 2004

Role of Pax2 in apoptosis resistance and proinvasive phenotype of Kaposi's sarcoma cells.

J Biol Chem 2004 Feb 19;279(6):4136-43. Epub 2003 Nov 19.

Cattedra di Nefrologia, Dipartimento di Medicina Interna and Centro Ricerca Medicina Sperimentale, Università di Torino, Torino 10126, Italy.

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http://dx.doi.org/10.1074/jbc.M306824200DOI Listing
February 2004

NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors.

Blood 2003 Mar 7;101(5):1919-27. Epub 2002 Nov 7.

Department of Pathology and Kaplan Comprehensive Cancer Center, and Department of Pediatric Oncology, New York University School of Medicine, New York, NY 10016, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2002-05-13
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http://dx.doi.org/10.1182/blood-2002-05-1343DOI Listing
March 2003

In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation.

Mol Cell Biol 2002 Dec;22(23):8375-87

Department of Pathology and NYU Cancer Institute. Division of Hematopathology, New York University School of Medicine, New York, New York 10016, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134052PMC
http://dx.doi.org/10.1128/mcb.22.23.8375-8387.2002DOI Listing
December 2002

Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death.

Oncogene 2002 Feb;21(7):1038-47

Department of Pathology and Kaplan Comprehensive Cancer Center, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1038/sj.onc.1205152DOI Listing
February 2002